AutismKB 2.0

Annotation Detail for SLC4A10


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Basic Information Top
Gene Symbol:SLC4A10 ( NBCn2,NCBE )
Gene Full Name: solute carrier family 4, sodium bicarbonate transporter, member 10
Band: 2q24.2
Quick LinksEntrez ID:57282; OMIM: 605556; Uniprot ID:S4A10_HUMAN; ENSEMBL ID: ENSG00000144290; HGNC ID: 13811
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Transmembrane transport of small molecules
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SLC4A10 mRNAaffects expression 16483693
D008345 Manganese Manganese results in decreased expression of SLC4A10 mRNAdecreases expression 17175027
C025340 manganese chloride manganese chloride results in decreased expression of SLC4A10 mRNAdecreases expression 17175027
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.3018287403
MESH:D000756 Anemia, Sideroblastic Manganese 12.6916910769
MESH:D000756 Anemia, Sideroblastic manganese chloride 12.6916910769
MESH:D017029 Epilepsy, Complex Partial marker/mechanism
MESH:D005909 Glioblastoma Manganese 4.1817043766
MESH:D020149 Manganese Poisoning Manganese 6.3919453300 16568477 16551646
MESH:D008607 Mental Retardation marker/mechanism
MESH:D009069 Movement Disorders Manganese 5.5416551646
MESH:D009410 Nerve Degeneration Manganese 4.6216551646
MESH:D010300 Parkinson Disease Manganese 3.5011181820
MESH:D020734 Parkinsonian Disorders Manganese 4.9216140633
Pathway ID Pathway Name
REACT:15518 Transmembrane transport of small molecules
Pharmacogenomics Knowledge Base Top
Drug Bank Top
No data
No data
Drugbank ID Action Drug Name Description
DB01390 substrate Woodward's Gripe Water Antidiarrheals
No data

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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