AutismKB 2.0

Annotation Detail for AMIGO1


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Basic Information Top
Gene Symbol:AMIGO1 ( AMIGO,AMIGO-1 )
Gene Full Name: adhesion molecule with Ig-like domain 1
Band: 1p13.3
Quick LinksEntrez ID:57463; OMIM: NA; Uniprot ID:AMGO1_HUMAN; ENSEMBL ID: ENSG00000181754; HGNC ID: 20824
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000638 Amiodarone Amiodarone results in increased expression of AMIGO1 mRNAincreases expression 19774075
D000643 Ammonium Chloride Ammonium Chloride affects the expression of AMIGO1 mRNAaffects expression 16483693
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of AMIGO1 mRNAdecreases expression 17484886
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.3018287403
MESH:D001145 Arrhythmias, Cardiac Amiodarone 4.2518057881 20041841 18218290
MESH:D001281 Atrial Fibrillation Amiodarone 4.2319698954 18651412
MESH:D001778 Blood Coagulation Disorders Amiodarone 4.3819483382
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.4318705752 15721981 3786805 15673190 10355542 16227642 16011737 15700767 16097048 16192424 16124888 16050911
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 1.8618788625
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 3.0119225199 15710769
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.8318974383
MESH:D056486 Drug-Induced Liver Injury Amiodarone 4.3715265979 18218290
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 4.3719085960 7120509 4309450 3732212 15968718 15998439 11566570 15027814 16227642 3786805 2869522 6623471 17522070 10092053 16177239 10915739 7440962 6884620 9327722 21278145 19336974 7179309
MESH:D005234 Fatty Liver Amiodarone 9.6014986274
MESH:D005234 Fatty Liver Carbon Tetrachloride 9.6012631006 16239168 12795759 15959796 19224547 16045604 61145 17595544
MESH:D005355 Fibrosis Carbon Tetrachloride 4.1018705752
MESH:D006505 Hepatitis Carbon Tetrachloride 4.1819110552 19900420
MESH:D006529 Hepatomegaly Amiodarone 4.4015265979
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 5.2716899240
MESH:D006937 Hypercholesterolemia Amiodarone 4.368137927 9751232
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.7415338365
MESH:D007037 Hypothyroidism Amiodarone 5.1718020914 17991464
MESH:D008064 Lipidoses Amiodarone 3.8217567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 3.0211903743 17334410 16943688 21278145 16239168 17174718 16221502 11408273 17157831
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 1.7518395914 12389079 18705752 17761835 10355542 15818738 18205269 18006644 15996030 14620537 18429990 12649538 18481824 15925388 17766677 17922224 18156304 16638106 12632514 16136751 18317297 12445418 18418968 17708605 12586293 14716496 17631135 12666154 15893842 17481882 17565644 17823541 18339082 14512876 15338365 15370692 12546737 18376398 13678700 18251166 16027843 17869086 12898905 18054572 16192424 17714472 18166357 15931870 17805973 17698563 12958196 18472094 15057751 11481614 16248980 17976157 17944888 14716833 15362042 14748882 16116963 17900296 12741479 18472332 17557913 15959796 17721639 15052691 17525996 18420326 15876570 16033810 17640975 16097048 18210741 16011737 18279442 20821823 12667390 12609069 12445421 18395095 15673190 18277467 18412020 14724832 18187930 16015684 15730626 15650968 12632512 18263696 15123356
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.1617285989 15830285 15720792 16246199 16964402
MESH:D017093 Liver Failure Carbon Tetrachloride 4.8215123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 4.1414706259 16899240
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 2.3519294768
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 2.8612014681 15583823
MESH:D008133 Long QT Syndrome Amiodarone 3.9217391786 11989578 15350150
MESH:D008171 Lung Diseases Amiodarone 3.6512587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 5.3418516814
MESH:D009181 Mycoses Amiodarone 5.7717974566 12754197
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9812490602 12832656 11597910
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.8318724381
MESH:D013276 Stomach Ulcer Amiodarone 3.7918087811
MESH:D013610 Tachycardia Amiodarone 4.8711238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.7719225199
MESH:D013959 Thyroid Diseases Amiodarone 5.6219731979
MESH:D013971 Thyrotoxicosis Amiodarone 5.5118020914 19584973
MESH:D016171 Torsades de Pointes Amiodarone 4.9311989578 17467628
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018