Annotation Detail for SHROOM4
Basic Information Top
| Gene Symbol: | SHROOM4 ( KIAA1202,SHAP ) |
|---|---|
| Gene Full Name: | shroom family member 4 |
| Band: | Xp11.22 |
| Quick Links | Entrez ID:57477; OMIM: 300579; Uniprot ID:SHRM4_HUMAN; ENSEMBL ID: ENSG00000158352; HGNC ID: 29215 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| No data |
| No data |
| No data |
| No data |
| Desease Name |
|---|
| Stocco dos Santos X-linked mental retardation syndrome |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of SHROOM4 mRNA | affects expression | 17562736 |
| D004041 | Dietary Fats | Dietary Fats results in increased expression of SHROOM4 mRNA | increases expression | 18042831 |
| C041786 | palm oil | palm oil results in increased expression of SHROOM4 mRNA | increases expression | 18042831 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.71 | 10982225 | |
| MESH:D001161 | Arteriosclerosis | Dietary Fats | 4.54 | 15238619 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D001943 | Breast Neoplasms | Dietary Fats | 2.24 | 20435547 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.81 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 19420014 16781746 10774834 12705907 19085960 12594235 15619225 17906064 15968718 14725611 11287661 12540782 12958197 12153990 10915739 14550746 11421492 16393943 11834606 19164858 16081117 18713872 19739265 11739529 16177239 18071297 14986274 19416960 17522070 16485898 16109766 11529661 12392966 2444490 16227642 17562736 19370779 19923254 11461765 10663392 11743745 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.96 | 19426721 | |
| MESH:D050171 | Dyslipidemias | Dietary Fats | 3.76 | 18367378 | |
| MESH:D005234 | Fatty Liver | Dietary Fats | 3.72 | 18296743 17967931 19551842 19004024 | |
| MESH:D005355 | Fibrosis | Dietary Fats | 4.17 | 18296743 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.54 | 16983495 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.06 | 16870215 | |
| MESH:D006937 | Hypercholesterolemia | Dietary Fats | 4.08 | 21332399 | |
| MESH:D006949 | Hyperlipidemias | Dietary Fats | 4.14 | 21332399 | |
| MESH:D007249 | Inflammation | Dietary Fats | 2.62 | 20412841 | |
| MESH:D007333 | Insulin Resistance | Dietary Fats | 3.37 | 11836018 18457598 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.42 | 15629191 12587719 | |
| MESH:D008103 | Liver Cirrhosis | Dietary Fats | 3.09 | 18296743 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 12969438 19460945 16611625 16610002 11587558 19014921 12587719 19784758 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.68 | 17185352 16871587 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.22 | 19513568 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.26 | 18514411 | |
| MESH:D009765 | Obesity | Dietary Fats | 2.36 | 20518802 20132043 19632207 18457598 21332399 11836018 18674790 17217161 16723640 | |
| MESH:D010146 | Pain | Acetaminophen | 2.77 | 16870215 | |
| OMIM:300434 | STOCCO DOS SANTOS X-LINKED MENTAL RETARDATION SYNDROME | marker/mechanism | |||
| MESH:D014581 | Urticaria | Acetaminophen | 3.50 | 10982225 | |
| MESH:D015430 | Weight Gain | Dietary Fats | 4.15 | 16723640 |
| No data |