AutismKB 2.0

Annotation Detail for USP31


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Basic Information Top
Gene Symbol:USP31 ( KIAA1203 )
Gene Full Name: ubiquitin specific peptidase 31
Band: 16p12.2
Quick LinksEntrez ID:57478; OMIM: NA; Uniprot ID:UBP31_HUMAN; ENSEMBL ID: ENSG00000103404; HGNC ID: 20060
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen MAP3K5 protein affects the reaction [Acetaminophen results in increased expression of USP31 mRNA]affects reaction|increases expression 18700144
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of USP31 mRNAdecreases expression 20018196
D016572 Cyclosporine Cyclosporine results in increased expression of USP31 mRNAincreases expression 20106945
C004648 testosterone enanthate testosterone enanthate affects the expression of USP31 mRNAaffects expression 17440010
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.4420889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.4412371664
MESH:D002779 Cholestasis Cyclosporine 3.2119486331
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6719923254 15968718 11834606 18071297 16485898 11461765 19420014 10663392 10774834 14725611 16081117 19739265 16177239 16781746 17562736 17522070 14986274 11421492 16227642 12705907 19164858 17906064 12392966 11739529 16393943 14550746 12594235 11529661 19370779 12958197 15619225 11743745 2444490 12540782 16109766 10915739 19085960 11287661 12153990 18713872 19416960
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1520426865
MESH:D005234 Fatty Liver Cyclosporine 3.2819224547
MESH:D005355 Fibrosis Cyclosporine 3.7012639820 12168785
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.858708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.0515720958
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 6.4717440010
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D006973 Hypertension Cyclosporine 2.2110903974
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.1615604871
MESH:D007674 Kidney Diseases Acetaminophen 6.4815629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 6.4810903974 18776723 8314463
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0812371664
MESH:D008107 Liver Diseases Acetaminophen 1.7012969438 11587558 19784758 16610002 16611625 12587719 19014921 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6317185352 16871587
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.5116801185
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.1617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6519348381 18481113
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D011230 Precancerous Conditions Cyclosporine 3.5912371664
MESH:D011565 Psoriasis Cyclosporine 2.3316882103
MESH:D014581 Urticaria Acetaminophen 3.4410982225
MESH:D014605 Uveitis Cyclosporine 4.711336536
MESH:D014985 Xerophthalmia Cyclosporine 5.1617120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018