AutismKB 2.0

Annotation Detail for MTUS1


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Basic Information Top
Gene Symbol:MTUS1 ( ATBP,ATIP,DKFZp586D1519,DKFZp686F20243,FLJ14295,KIAA1288,MP44,MTSG1 )
Gene Full Name: microtubule associated tumor suppressor 1
Band: 8p22
Quick LinksEntrez ID:57509; OMIM: 609589; Uniprot ID:MTUS1_HUMAN; ENSEMBL ID: ENSG00000129422; HGNC ID: 29789
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of MTUS1 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of MTUS1 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of MTUS1 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of MTUS1 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of MTUS1 mRNAaffects expression 16483693
D016589 Astemizole Astemizole results in decreased expression of MTUS1 mRNAdecreases expression 20221588
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MTUS1 mRNAaffects cotreatment|increases expression 18164116
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of MTUS1 mRNAdecreases expression 20106945
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of MTUS1 mRNAdecreases expression 20504355
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MTUS1 mRNAdecreases expression 19150397
20018196
C055494 caffeic acid phenethyl ester caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of MTUS1 mRNA]decreases reaction|increases expression 20360939
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of MTUS1 mRNAaffects expression 17484886
D016572 Cyclosporine Cyclosporine results in decreased expression of MTUS1 mRNAdecreases expression 20106945
C041517 dibenzo(a,l)pyrene dibenzo(a,l)pyrene results in increased expression of MTUS1 mRNAincreases expression 15735009
D004041 Dietary Fats Dietary Fats results in increased expression of MTUS1 mRNAincreases expression 18042831
D004052 Diethylnitrosamine caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of MTUS1 mRNA]decreases reaction|increases expression 20360939
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MTUS1 mRNAaffects cotreatment|increases expression 18164116
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of MTUS1 mRNAincreases expression 20360939
D002117 Calcitriol Calcitriol results in decreased expression of MTUS1 mRNAdecreases expression 16002434
D004958 Estradiol Estradiol results in decreased expression of MTUS1 mRNAdecreases expression 20106945
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of MTUS1 mRNAincreases expression 17557909
D005047 Etoposide MTUS1 protein affects the susceptibility to Etoposideaffects response to substance 16217747
C016599 mono-(2-ethylhexyl)phthalate mono-(2-ethylhexyl)phthalate results in increased expression of MTUS1 mRNAincreases expression 16809437
C041786 palm oil palm oil results in increased expression of MTUS1 mRNAincreases expression 18042831
C073402 PD 123319 PD 123319 affects the reaction [AGT protein promotes the reaction [PTPN6 protein binds to MTUS1 protein]]affects binding|affects reaction|increases reaction 17068200
C006253 pirinixic acid pirinixic acid results in increased expression of MTUS1 mRNAincreases expression 18301758
C004648 testosterone enanthate testosterone enanthate affects the expression of MTUS1 mRNAaffects expression 17440010
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of MTUS1 mRNAdecreases expression 19490992
D019772 Topotecan MTUS1 protein affects the susceptibility to Topotecanaffects response to substance 16217747
C081489 valsartan valsartan promotes the reaction [AGT protein promotes the reaction [PTPN6 protein binds to MTUS1 protein]]affects binding|increases reaction 17068200
D015032 Zinc Zinc results in increased expression of MTUS1 mRNAincreases expression 17074742
D019287 Zinc Sulfate Zinc Sulfate results in increased expression of MTUS1 mRNAincreases expression 17074742
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.5914514962 15322242 11752688
MESH:D000138 Acidosis Ammonium Chloride 9.7418287403
MESH:D000138 Acidosis Zinc Sulfate 9.747265320
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.6817505938
MESH:D000169 Acrodermatitis Zinc 5.1417202136 17190629 16889938
MESH:D055371 Acute Lung Injury pirinixic acid 2.8818653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 6.5920127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 6.5911473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.5914692618
MESH:D000236 Adenoma Benzo(a)pyrene 10.336695378
MESH:D000236 Adenoma beta-Naphthoflavone 10.3319389873
MESH:D000236 Adenoma Diethylnitrosamine 10.336695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 15.7517162532 19052882 16434500 19061943 18056438 17620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 15.7516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 15.7516835633
MESH:D000544 Alzheimer Disease Zinc 2.7016410023 16325427 16580781 17119284
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7211748828
MESH:D000755 Anemia, Sickle Cell Zinc 4.6516916123
MESH:D000799 Angioedema Acetaminophen 11.1410982225
MESH:D000799 Angioedema Astemizole 11.142883202
MESH:D000860 Anoxia Zinc Sulfate 4.767265320
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.8219183758
MESH:D001161 Arteriosclerosis Dietary Fats 9.0515238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.0511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5015885639
MESH:D001249 Asthma Zinc 2.8817085522
MESH:D001321 Autistic Disorder Acetaminophen 1.4418445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 7.9919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 7.9912125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6015746008
MESH:D019046 Bone Marrow Neoplasms Etoposide 4.8914601052
MESH:D001930 Brain Injuries Zinc 4.4317109824
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 3.5920146248 17474063
MESH:D001943 Breast Neoplasms Calcitriol 3.5911237771
MESH:D001943 Breast Neoplasms Dietary Fats 3.5920435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 3.5917474063
MESH:D001943 Breast Neoplasms Estradiol 3.5919861407 14630087 17289903 16675129 18497071 17261762 12948864 17018787
MESH:D001943 Breast Neoplasms Etoposide 3.5916322251
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.5920435547
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.2016111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.5216050911 15673190 16124888 16227642 16192424 15721981 16097048 10355542 16011737 18705752 15700767 3786805
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.5916835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 13.3816705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 13.3816705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 13.383084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 13.3812907637 12619106 21507988
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 13.3818788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 13.3819519916 10672840 17162532 18788625 16830150 18971187 20935162 18506893 19822196 19701751 16540662 19052882 11831363 16878318 20512989 20727157 18978308 18665156 18494052 16681979 16807293 18393292 17978847 10737359 18785209 16288022 19107877 20514400 19383236 19208518 20101231 20432363 17428255 18210153 21159647 19418558 20524982 17055752 19171122 3084413 19335982 19919837 19394651 16328049 3581430 18056438 20084675 16569478 16779866 16502159 16698587 18691550 19539802 16935385 17138121 17761372 20007298 20214788 17173139
MESH:D006528 Carcinoma, Hepatocellular Estradiol 13.3816924424
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.1620419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 7.1611237771
MESH:D002294 Carcinoma, Squamous Cell Zinc 7.1616543248
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.6416120746 18670907 18850075
MESH:D006332 Cardiomegaly valsartan 6.6419597038
MESH:D009202 Cardiomyopathies valsartan 4.2716247790
MESH:D002318 Cardiovascular Diseases valsartan 7.3511230374
MESH:D002318 Cardiovascular Diseases Zinc 7.3516936243
MESH:D002386 Cataract Acetaminophen 2.4310977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 19.186135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 19.1820889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 19.1812371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 19.1817174075 2727394 21159647 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 19.1818566989
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.5919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.5916835633
MESH:D002779 Cholestasis Cyclosporine 12.2319486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.2316105132 17681005 16919318 17110522 15861022 17333356 11677210
MESH:D002779 Cholestasis pirinixic acid 12.2319176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.9912621046 15340226 15668235 8697196 16354765
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8414669216 17141729
MESH:D003324 Coronary Artery Disease valsartan 3.8017719468
MESH:D003384 Coxsackievirus Infections valsartan 5.5820392896
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.5920055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Zinc 2.5919302082
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.0318551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.0318551238
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3018249437
MESH:D003920 Diabetes Mellitus Zinc 3.9816479319
MESH:D003921 Diabetes Mellitus, Experimental valsartan 4.3911508273
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 3.9920387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.9917107852
MESH:D003928 Diabetic Nephropathies Estradiol 8.5919279558
MESH:D003928 Diabetic Nephropathies valsartan 8.5911427623 18630688
MESH:D004244 Dizziness Astemizole 6.203105558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 14.1918551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 14.1918551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 14.1911739529 15968718 19420014 19085960 11743745 16177239 12540782 11421492 17562736 17522070 12153990 11834606 15619225 12594235 16781746 17906064 19923254 18071297 10774834 10915739 14550746 14986274 19370779 12958197 11529661 16109766 2444490 12705907 12392966 19164858 14725611 11287661 16393943 16227642 11461765 16081117 19416960 19739265 10663392 18713872 16485898
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 14.1915027814 6884620 17522070 19336974 16177239 3786805 7179309 7120509 7440962 15998439 10915739 11566570 4309450 6623471 21278145 10092053 16227642 9327722 19085960 3732212 2869522 15968718
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 14.1919107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 14.1920420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.8319426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.5711462148
MESH:D050171 Dyslipidemias Dietary Fats 3.2718367378
MESH:D004487 Edema pirinixic acid 5.7712083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.7712711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.6415322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 8.2615138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.2612538720
MESH:D016889 Endometrial Neoplasms Estradiol 2.8111473722 19148513 18566989
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.8010568697 9294722
MESH:D004802 Eosinophilia Astemizole 4.551355641
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.8516302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.8720426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 6.8716530937
MESH:D004938 Esophageal Neoplasms Zinc 6.8716543248
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8211564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 27.6516045604 12631006 15959796 12795759 17595544 19224547 16239168 61145
MESH:D005234 Fatty Liver Cyclosporine 27.6519224547
MESH:D005234 Fatty Liver Dietary Fats 27.6517967931 19004024 18296743 19551842
MESH:D005234 Fatty Liver Diethylnitrosamine 27.6520387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 27.6515345470
MESH:D005234 Fatty Liver pirinixic acid 27.6520131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2011858732
MESH:D005355 Fibrosis Carbon Tetrachloride 25.0018705752
MESH:D005355 Fibrosis Cyclosporine 25.0012639820 12168785
MESH:D005355 Fibrosis Dietary Fats 25.0018296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 25.0020067830
MESH:D005355 Fibrosis valsartan 25.0016893502
MESH:D005499 Folliculitis Astemizole 5.651671328
MESH:D005756 Gastritis Acetaminophen 10.2816983495
MESH:D005756 Gastritis Zinc 10.2817241300
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.958708960
MESH:D015432 Glomerulonephritis, Membranoproliferative valsartan 5.2916928621
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3310696789
MESH:D006130 Growth Disorders Zinc 3.8017217573
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 5.9920471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.9911294989 10048152
MESH:D006333 Heart Failure pirinixic acid 11.0720558911
MESH:D006333 Heart Failure valsartan 11.0719027736
MESH:D006333 Heart Failure Zinc 11.0717162251
MESH:D006335 Heart Injuries Zinc 5.5017074742
MESH:D016481 Helicobacter Infections Zinc 4.2917241300
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.1615720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1011000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.3519900420 19110552
MESH:D006527 Hepatolenticular Degeneration Zinc 10.4617276780
MESH:D006527 Hepatolenticular Degeneration Zinc Sulfate 10.4617063115
MESH:D006529 Hepatomegaly pirinixic acid 7.4119176532 16221962 19772884 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.4112621046 15340226 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.7615709030
MESH:D006561 Herpes Simplex Etoposide 4.3010809021
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.4817440010
MESH:D006689 Hodgkin Disease Etoposide 3.6615147373 18180244 17606976 16135485 16200630
MESH:D019584 Hot Flashes Estradiol 3.4917088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.788697196 16354765 15340226 18606429 16959395
MESH:D006930 Hyperalgesia Acetaminophen 2.5016870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.2716899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.3621332399
MESH:D006943 Hyperglycemia pirinixic acid 2.9620558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.3721332399
MESH:D006973 Hypertension Cyclosporine 8.1010903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.1018850075 18670907
MESH:D006973 Hypertension valsartan 8.1020102058 12850387 18344623 18390891 16475468 10903974 11427623 12692753
MESH:D006974 Hypertension, Malignant valsartan 6.1411560862
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.8315338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.5516945680 16569931
MESH:D007022 Hypotension Zinc Sulfate 4.237265320
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.3217937319
MESH:D007249 Inflammation Dietary Fats 7.4820412841
MESH:D007249 Inflammation Diethylnitrosamine 7.4818785209
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.4812200463 12878042
MESH:D007333 Insulin Resistance Dietary Fats 11.3111836018 18457598
MESH:D007333 Insulin Resistance Estradiol 11.3116393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 11.3116306350
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.3610783313
MESH:D007511 Ischemia Zinc 4.3716584753
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1016580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.1715604871
MESH:D007674 Kidney Diseases Acetaminophen 21.9212587719 15629191
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 21.9215369732
MESH:D007674 Kidney Diseases Cyclosporine 21.928314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 21.9215618244
MESH:D007674 Kidney Diseases valsartan 21.9210903974 12164870 16893502
MESH:D007674 Kidney Diseases Zinc 21.9216960431
MESH:D007676 Kidney Failure, Chronic Zinc 4.1816518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 16.0016705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 16.0016705839
MESH:D007680 Kidney Neoplasms Cyclosporine 16.0012371664
MESH:D007680 Kidney Neoplasms Estradiol 16.0015610895
MESH:D016773 Leishmaniasis, Cutaneous Zinc Sulfate 4.0515237267
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 3.8216766008
MESH:D017513 Lichen Nitidus Astemizole 6.202563723
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.1817157831 16943688 17334410 11903743 21278145 11408273 16239168 17174718 16221502
MESH:D008103 Liver Cirrhosis Dietary Fats 10.1818296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 10.1818522880 19638242 18665156 18407596 20032147
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 6.3712389079 17721639 18054572 18395095 17805973 18317297 15876570 17944888 17761835 14748882 16248980 14716833 18006644 18205269 18412020 18420326 15730626 16033810 14512876 18279442 13678700 16027843 15370692 14724832 14716496 15996030 15925388 17869086 18418968 15650968 12667390 10355542 17557913 12958196 15818738 15893842 17698563 18277467 15673190 17481882 16015684 18263696 17823541 16097048 16638106 12741479 12445421 18472332 18395914 20821823 14620537 16136751 18210741 11481614 17640975 17900296 17766677 18339082 18156304 12586293 18472094 15123356 18187930 17976157 18376398 16011737 15931870 12649538 17922224 18481824 12666154 15362042 17714472 12609069 12898905 18166357 17708605 17565644 12546737 15052691 12445418 15959796 12632514 18429990 18251166 18705752 15338365 15057751 17525996 16116963 17631135 16192424 12632512
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.3714659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.3715474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.3712878042
MESH:D008106 Liver Cirrhosis, Experimental valsartan 6.3715504291 15619341 16872305
MESH:D008107 Liver Diseases Acetaminophen 6.0519784758 19014921 12969438 16611625 16610002 19460945 11587558 12587719
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.0517285989 15720792 16964402 16246199 15830285
MESH:D008107 Liver Diseases Diethylnitrosamine 6.0517034775
MESH:D017093 Liver Failure Carbon Tetrachloride 3.9115123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.6516871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.6516899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 24.187678174
MESH:D008113 Liver Neoplasms Aflatoxin B1 24.189163691 2125692 18177683 15890375
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 24.1820195826 21137059
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 24.1819389873 21295105
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 24.1819294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 24.1820405173 2422723 15885732 19426721 12112319 20501860 12771043 18648771 20583210 21071580 19256749 18978307 19255062 18644402 9163691 18977376 16942905 19254457 19833225 19812893 19427195 21278145 21167192 15175105 19996281 19499222 19073162 20452335 20137499 20101389 20434301 19090486 21047994 19294768 19690152 20118626 19850985 19638242 20492335 19551842 10737359 18754104 19642983 2862719
MESH:D008113 Liver Neoplasms pirinixic acid 24.1820007298 16377806 15890375
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 24.1816984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 21.256135515 2876786 2876784
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 21.258603461
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 21.2518164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 21.2512014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 21.2518164116 19009564 18282651 16267830 18093689 18544905 19126423 17174075 18308698 2563599 19519916 18775883 16842330 18079962 17854601 19004024 3124819 19539802 17942915 9362446 18253720 21159647
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 21.2512151625
MESH:D008133 Long QT Syndrome Astemizole 4.4018472280 11989578
MESH:D008175 Lung Neoplasms Aflatoxin B1 4.5514755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 4.5518520028 17053015 20464547 6695378 18569708 20869020 20064080 18816296 20135361
MESH:D008175 Lung Neoplasms Diethylnitrosamine 4.5520970405 20512841 21163286 6695378
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.5519555203 11884234
MESH:D008223 Lymphoma Etoposide 3.7412854902 12556972
MESH:D008288 Malaria Astemizole 4.5716816845
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 5.6616891317 11807958 17203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Zinc 5.6612773700
MESH:D020149 Manganese Poisoning Estradiol 4.2219453300
MESH:D008546 Melanoma, Experimental Acetaminophen 3.3119513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5216801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.9916381670
MESH:D009135 Muscular Diseases pirinixic acid 3.2516239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.0319151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.5916810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.5916411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 9.4718551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 9.4718551238 7678174
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.469029167 3581430
MESH:D009369 Neoplasms Benzo(a)pyrene 4.3911141357
MESH:D009369 Neoplasms pirinixic acid 4.3917405874
MESH:D009389 Neovascularization, Pathologic Estradiol 3.4717289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.1717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.0618481113 19348381
MESH:D009421 Nervous System Malformations Estradiol 8.6316427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.6314600291
MESH:D009447 Neuroblastoma Topotecan 3.7115176712
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.4818514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.4820387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.8520387270
MESH:D009759 Nystagmus, Pathologic Astemizole 6.206135121
MESH:D009765 Obesity Dietary Fats 4.2019632207 18457598 20132043 16723640 11836018 17217161 18674790 21332399 20518802
MESH:D009765 Obesity pirinixic acid 4.2020558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 8.1312819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.1316049721
MESH:D010051 Ovarian Neoplasms Estradiol 2.1419401270
MESH:D010146 Pain Acetaminophen 2.1916870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.2316540662
MESH:D010190 Pancreatic Neoplasms Etoposide 5.2319003803
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4411578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9812520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3118163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.2112371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.212563599
MESH:D011225 Pre-Eclampsia Zinc 3.9817114810
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.9311896295 11399792 11118676 11222880
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.5215572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.6520887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.9017292933
MESH:D011471 Prostatic Neoplasms Calcitriol 1.9012479363 18247401 16289102 15754350 16644109
MESH:D011471 Prostatic Neoplasms Estradiol 1.9016740699
MESH:D011471 Prostatic Neoplasms Etoposide 1.9017172428
MESH:D011471 Prostatic Neoplasms Zinc 1.9012429649 16700911 16517595 16606632
MESH:D011507 Proteinuria valsartan 4.6117664856 18344623 12164870
MESH:D011537 Pruritus Ethinyl Estradiol 3.0516919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.1416882103
MESH:D011658 Pulmonary Fibrosis valsartan 3.7117241526
MESH:D015427 Reperfusion Injury pirinixic acid 2.2619058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5918990726
MESH:D012162 Retinal Degeneration Zinc 3.9316584753
MESH:D012221 Rhinitis, Allergic, Perennial Astemizole 5.1610822083
MESH:D012512 Sarcoma, Ewing's Etoposide 4.4514601052
MESH:D012640 Seizures 2,4-dinitrotoluene 5.2818551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.2818551238
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.0619755658 10029692
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.0616192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.6816709447
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.262093021 20155912
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.2618456281
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9315669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6412697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 2.797505956
MESH:D013978 Tibial Fractures Estradiol 4.4219048282
MESH:D014062 Tongue Neoplasms Zinc 4.1716543248
MESH:D016171 Torsades de Pointes Astemizole 4.949583453 8256756
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 7.6516049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 7.6516049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 7.6517053015
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.1110091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.1110091137
MESH:D014581 Urticaria Acetaminophen 8.2310982225
MESH:D014581 Urticaria Astemizole 8.232859714 3097109 3134034 1976298 2883202 3080510 2568013 2565098 1683191 2885854 2568189 2147912
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.0514692618
MESH:D014605 Uveitis Cyclosporine 3.721336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3312125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3014671159 15869587
MESH:D020257 Ventricular Remodeling valsartan 5.4319027736
MESH:D014717 Vertigo Astemizole 6.203105558
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9815886252
MESH:D015430 Weight Gain Dietary Fats 3.5216723640
MESH:D014985 Xerophthalmia Cyclosporine 4.1717120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA134968054
    • Releated gene ID Related gene Name
    PA44AGTR2
    No data
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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