Gene Symbol:	GPR158 ( FLJ37801,KIAA1136,RP11-59G22.1 )
Gene Full Name:	G protein-coupled receptor 158
Band:	10p12.1
Quick Links	Entrez ID:57512; OMIM: NA; Uniprot ID:GP158_HUMAN; ENSEMBL ID: ENSG00000151025; HGNC ID: 23689
Relate to Another Database:	SFARIGene; denovo-db

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
C023514	2,6-dinitrotoluene	2,6-dinitrotoluene results in decreased expression of GPR158 mRNA	decreases expression	20406850
D000082	Acetaminophen	Acetaminophen affects the expression of GPR158 mRNA	affects expression	17562736
D016572	Cyclosporine	Cyclosporine results in increased expression of GPR158 mRNA	increases expression	20106945

Disease ID	Disease Name	Inference Chemical Name	Inference Score	Publication
MESH:D000799	Angioedema	Acetaminophen	4.71	10982225
MESH:D001321	Autistic Disorder	Acetaminophen	1.39	18445737
MESH:D006528	Carcinoma, Hepatocellular	2,6-dinitrotoluene	2.97	16705839
MESH:D006528	Carcinoma, Hepatocellular	Acetaminophen	2.97	3084413
MESH:D002386	Cataract	Acetaminophen	2.81	10977129
MESH:D002471	Cell Transformation, Neoplastic	2,6-dinitrotoluene	7.56	6135515
MESH:D002471	Cell Transformation, Neoplastic	Cyclosporine	7.56	12371664
MESH:D002779	Cholestasis	Cyclosporine	3.24	19486331
MESH:D003490	Cyanosis	2,6-dinitrotoluene	4.67	18551238
MESH:D056486	Drug-Induced Liver Injury	2,6-dinitrotoluene	4.05	18551238 21346803
MESH:D056486	Drug-Induced Liver Injury	Acetaminophen	4.05	10663392 19416960 19420014 16109766 2444490 19085960 19923254 14986274 15619225 17522070 16485898 10915739 17562736 16177239 10774834 19739265 19164858 12705907 18713872 11834606 12594235 16081117 19370779 16393943 12153990 12392966 11739529 14725611 12540782 11421492 11529661 16227642 14550746 11461765 11743745 16781746 17906064 18071297 12958197 11287661 15968718
MESH:D056487	Drug-Induced Liver Injury, Chronic	Acetaminophen	4.96	19426721
MESH:D005234	Fatty Liver	Cyclosporine	3.34	19224547
MESH:D005355	Fibrosis	Cyclosporine	3.79	12168785 12639820
MESH:D005756	Gastritis	Acetaminophen	4.54	16983495
MESH:D005885	Gingival Hyperplasia	Cyclosporine	4.96	8708960
MESH:D006457	Hemoglobinuria, Paroxysmal	Cyclosporine	5.16	15720958
MESH:D006930	Hyperalgesia	Acetaminophen	3.06	16870215
MESH:D006973	Hypertension	Cyclosporine	2.23	10903974
MESH:D007638	Keratoconjunctivitis Sicca	Cyclosporine	5.31	15604871
MESH:D007674	Kidney Diseases	Acetaminophen	6.55	15629191 12587719
MESH:D007674	Kidney Diseases	Cyclosporine	6.55	18776723 10903974 8314463
MESH:D007680	Kidney Neoplasms	2,6-dinitrotoluene	8.59	16705839
MESH:D007680	Kidney Neoplasms	Cyclosporine	8.59	12371664
MESH:D008107	Liver Diseases	Acetaminophen	1.71	11587558 12969438 16611625 19014921 16610002 19460945 12587719 19784758
MESH:D017114	Liver Failure, Acute	Acetaminophen	3.68	17185352 16871587
MESH:D008113	Liver Neoplasms	2,6-dinitrotoluene	2.28	7678174
MESH:D008114	Liver Neoplasms, Experimental	2,6-dinitrotoluene	2.79	2876784 2876786 6135515
MESH:D008546	Melanoma, Experimental	Acetaminophen	4.22	19513568
MESH:D008664	Metal Metabolism, Inborn Errors	Cyclosporine	5.65	16801185
MESH:D009336	Necrosis	2,6-dinitrotoluene	4.60	18551238 7678174
MESH:D009402	Nephrosis, Lipoid	Cyclosporine	5.31	17954296
MESH:D009404	Nephrotic Syndrome	Cyclosporine	3.70	18481113 19348381
MESH:D019636	Neurodegenerative Diseases	Acetaminophen	3.26	18514411
MESH:D009784	Occupational Diseases	2,6-dinitrotoluene	3.88	16049721
MESH:D010146	Pain	Acetaminophen	2.77	16870215
MESH:D011230	Precancerous Conditions	Cyclosporine	3.64	12371664
MESH:D011565	Psoriasis	Cyclosporine	2.34	16882103
MESH:D012640	Seizures	2,6-dinitrotoluene	2.82	18551238
MESH:D001749	Urinary Bladder Neoplasms	2,6-dinitrotoluene	2.42	16049721
MESH:D014571	Urologic Neoplasms	2,6-dinitrotoluene	5.06	10091137
MESH:D014581	Urticaria	Acetaminophen	3.50	10982225
MESH:D014605	Uveitis	Cyclosporine	4.85	1336536
MESH:D014985	Xerophthalmia	Cyclosporine	5.31	17120751

AutismKB 2.0

Annotation Detail for GPR158

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics