Annotation Detail for HECW2
Basic Information
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| Gene Symbol: | HECW2 ( DKFZp686M17164,NEDL2 ) |
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| Gene Full Name: | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 |
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| Band: | 2q32.3 |
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| Quick Links | Entrez ID:57520; OMIM: NA; Uniprot ID:HECW2_HUMAN; ENSEMBL ID: ENSG00000138411; HGNC ID: 29853 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of HECW2 mRNA | affects expression | 17562736
|
| D001151 |
Arsenic |
Arsenic results in decreased expression of HECW2 mRNA | decreases expression | 19654921
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D018246 |
Adrenocortical Adenoma |
|
Arsenic |
6.28 | 17306315 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.91 | 10982225 |
| MESH:D020261 |
Arsenic Poisoning |
|
Arsenic |
2.97 | 12569548 18414634 16835338 16251483 |
| MESH:D050197 |
Atherosclerosis |
|
Arsenic |
3.51 | 12928151 19371607 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.39 | 18445737 |
| MESH:D002280 |
Carcinoma, Basal Cell |
|
Arsenic |
3.83 | 15504454 17687452 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
3.18 | 3084413 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Arsenic |
3.18 | 17306315 16507464 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Arsenic |
2.79 | 18922899 15504454 17687452 |
| MESH:D002295 |
Carcinoma, Transitional Cell |
|
Arsenic |
4.58 | 18640142 |
| MESH:D002318 |
Cardiovascular Diseases |
|
Arsenic |
3.77 | 15738583 19152805 17938729 |
| MESH:D002340 |
Carotid Artery Diseases |
|
Arsenic |
4.78 | 18022660 16973168 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.83 | 10977129 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
1.68 | 16227642 16485898 19416960 11529661 16109766 14725611 11287661 16393943 10915739 19370779 19739265 15619225 12958197 19164858 12705907 17562736 18071297 18713872 11461765 2444490 19085960 19923254 14986274 12540782 16081117 10774834 11834606 12153990 16177239 12594235 17906064 11739529 15968718 10663392 11421492 12392966 19420014 11743745 17522070 16781746 14550746 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
5.17 | 19426721 |
| MESH:D005534 |
Foot Diseases |
|
Arsenic |
6.63 | 6392382 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.74 | 16983495 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
3.11 | 16870215 |
| MESH:D017488 |
Hyperkeratosis, Epidermolytic |
|
Arsenic |
4.96 | 17050553 |
| MESH:D006973 |
Hypertension |
|
Arsenic |
3.01 | 16076760 9931084 11953799 |
| MESH:D006987 |
Hypesthesia |
|
Arsenic |
6.63 | 16093927 |
| MESH:D007642 |
Keratosis |
|
Arsenic |
5.88 | 16930632 12749816 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.44 | 12587719 15629191 |
| MESH:D015473 |
Leukemia, Promyelocytic, Acute |
|
Arsenic |
3.85 | 17339181 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
4.38 | 12969438 16611625 19460945 16610002 19784758 11587558 19014921 12587719 |
| MESH:D008107 |
Liver Diseases |
|
Arsenic |
4.38 | 11134558 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.74 | 17185352 16871587 |
| MESH:D008113 |
Liver Neoplasms |
|
Arsenic |
2.82 | 16368122 |
| MESH:D008175 |
Lung Neoplasms |
|
Arsenic |
2.21 | 19168569 17306315 17976673 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.33 | 19513568 |
| MESH:D017202 |
Myocardial Ischemia |
|
Arsenic |
4.39 | 15371236 |
| MESH:D009436 |
Neural Tube Defects |
|
Arsenic |
3.75 | 16620997 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.31 | 18514411 |
| MESH:D020078 |
Neurogenic Inflammation |
|
Arsenic |
4.98 | 17056641 |
| MESH:D010051 |
Ovarian Neoplasms |
|
Arsenic |
2.86 | 17306315 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.82 | 16870215 |
| MESH:D010523 |
Peripheral Nervous System Diseases |
|
Arsenic |
4.85 | 16093927 |
| MESH:D016491 |
Peripheral Vascular Diseases |
|
Arsenic |
5.88 | 16905509 6392382 15371236 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Arsenic |
3.54 | 16140617 |
| MESH:D011507 |
Proteinuria |
|
Arsenic |
4.61 | 21343184 |
| MESH:D012871 |
Skin Diseases |
|
Arsenic |
2.84 | 17548696 19834688 17453740 16702368 17050553 17938729 16353154 18709164 15952646 6392382 16759981 |
| MESH:D012878 |
Skin Neoplasms |
|
Arsenic |
3.19 | 17029826 16251483 17976673 17050553 15504454 19538983 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Arsenic |
2.96 | 11144890 18640142 17976673 19429237 19322015 17306315 15987713 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.58 | 10982225 |
| MESH:D014652 |
Vascular Diseases |
|
Arsenic |
5.62 | 17056641 |
Related Pathway Information