AutismKB 2.0

Annotation Detail for MIB1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MIB1 ( DIP-1,DKFZp686I0769,DKFZp761M1710,FLJ90676,MGC129659,MGC129660,MIB,ZZANK2,ZZZ6 )
Gene Full Name: mindbomb homolog 1 (Drosophila)
Band: 18q11.2
Quick LinksEntrez ID:57534; OMIM: 608677; Uniprot ID:MIB1_HUMAN; ENSEMBL ID: ENSG00000101752; HGNC ID: 21086
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
No data
Pathway IDPathway Name
200013Notch signaling pathway
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1860Brain tumor
2035Brain disease
2223Central nervous system disease
2242Nervous system tumor
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of MIB1 mRNAaffects expression 21346803
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MIB1 mRNAdecreases expression 20018196
D004041 Dietary Fats Dietary Fats results in increased expression of MIB1 mRNAincreases expression 18042831
D002117 Calcitriol Calcitriol results in increased expression of MIB1 mRNAincreases expression 16002434
C041786 palm oil palm oil results in increased expression of MIB1 mRNAincreases expression 18042831
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D001161 Arteriosclerosis Dietary Fats 4.3715238619
MESH:D001943 Breast Neoplasms Calcitriol 2.2911237771
MESH:D001943 Breast Neoplasms Dietary Fats 2.2920435547
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 1.7916705839
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 2.7011237771
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 7.446135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.4420889678
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.5018551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 2.0418551238 21346803
MESH:D050171 Dyslipidemias Dietary Fats 3.7018367378
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 4.3715138306
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1420426865
MESH:D005234 Fatty Liver Dietary Fats 3.6119551842 17967931 19004024 18296743
MESH:D005355 Fibrosis Dietary Fats 4.0118296743
MESH:D006937 Hypercholesterolemia Dietary Fats 3.9721332399
MESH:D006949 Hyperlipidemias Dietary Fats 4.0221332399
MESH:D007249 Inflammation Dietary Fats 2.5920412841
MESH:D007333 Insulin Resistance Dietary Fats 3.3218457598 11836018
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.2816705839
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0518296743
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.257678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.746135515 2876784 2876786
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.407678174 18551238
MESH:D009765 Obesity Dietary Fats 2.3517217161 18674790 20132043 11836018 21332399 19632207 20518802 16723640 18457598
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.7816049721
MESH:D011470 Prostatic Hyperplasia Calcitriol 5.3215572423
MESH:D011471 Prostatic Neoplasms Calcitriol 3.4918247401 16289102 15754350 16644109 12479363
MESH:D012640 Seizures 2,6-dinitrotoluene 2.7618551238
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.4016049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.8610091137
MESH:D015430 Weight Gain Dietary Fats 4.0616723640
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved