AutismKB 2.0

Annotation Detail for BAI2


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Basic Information Top
Gene Symbol:BAI2 ( - )
Gene Full Name: brain-specific angiogenesis inhibitor 2
Band: 1p35
Quick LinksEntrez ID:576; OMIM: 602683; Uniprot ID:BAI2_HUMAN; ENSEMBL ID: ENSG00000121753; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of BAI2 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BAI2 mRNAaffects cotreatment|increases expression 17942748
D020849 Raloxifene Raloxifene affects the expression of BAI2 mRNAaffects expression 14699072
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BAI2 mRNAaffects cotreatment|increases expression 17942748
D014635 Valproic Acid Valproic Acid results in increased expression of BAI2 mRNAincreases expression 19101580
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 10.5011752688 14514962 15322242
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 10.508875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.3519490988
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.6617505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8814692618
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 4.0116835633
MESH:D000419 Albuminuria Raloxifene 5.1017451421 17308373
MESH:D000544 Alzheimer Disease Raloxifene 2.6015800139
MESH:D000550 Amblyopia Valproic Acid 5.9617688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.3411748828
MESH:D001008 Anxiety Disorders Valproic Acid 3.9017497229
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.0211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8915885639
MESH:D001321 Autistic Disorder Valproic Acid 1.9817688650 17507914 18177632 20603192 18775368 18396377 16609825 18558336 18316065 18940202 17157402 18985861 15238991 19460635 19232924
MESH:D001714 Bipolar Disorder Valproic Acid 3.2420046352 17594078
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.4712125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.5115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 8.8015746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 8.808888407
MESH:D001930 Brain Injuries Raloxifene 5.0416580743
MESH:D001943 Breast Neoplasms Raloxifene 2.0917440819 17595753 15758505 17261762 15775269 16837676 17893378 17952589 16912660 17049068 17242785 15572757
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.0920435547
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 3.1216835633
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 4.4717572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.5616120746 18670907 18850075
MESH:D002318 Cardiovascular Diseases Raloxifene 3.7115775269
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8220734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.5316835633
MESH:D002779 Cholestasis Ethinyl Estradiol 3.1711677210 16919318 17333356 17681005 17110522 16105132 15861022
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.2416354765 12621046 15340226 15668235 8697196
MESH:D003072 Cognition Disorders Raloxifene 5.1815800139
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.4314669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.5610048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Valproic Acid 2.5617688650 16575769 8888407
MESH:D003865 Depressive Disorder, Major Raloxifene 4.5317474826
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7417107852
MESH:D003928 Diabetic Nephropathies Raloxifene 4.3017308373 15920148 17451421
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 4.0820420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 4.0819641884 1733752
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 3.0511462148
MESH:D004421 Dystonia Valproic Acid 4.511851702
MESH:D004487 Edema Raloxifene 8.2915860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 8.2911000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.6218230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 10.8512538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 10.8515845917
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.429294722 10568697
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.713659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 4.643922381 16628512
MESH:D004827 Epilepsy Valproic Acid 3.1118234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.966426943 6254150 7562514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.867750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.693659116
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.3111564622
MESH:D005234 Fatty Liver Ethinyl Estradiol 15.7715345470
MESH:D005234 Fatty Liver Raloxifene 15.7717473493
MESH:D005234 Fatty Liver Valproic Acid 15.7714986274 19224547
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 4.0211858732
MESH:D005315 Fetal Diseases Valproic Acid 5.6116575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.6418558336 8888407
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.5120067830
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.3210696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.5110048152 11294989
MESH:D006331 Heart Diseases Raloxifene 3.8011110106
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.7611000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.4515340226 12621046 16120746
MESH:D006849 Hydrocephalus Valproic Acid 5.5017688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.7715340226 18606429 8697196 16354765 16959395
MESH:D006973 Hypertension Raloxifene 5.6317577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.6318850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 4.3716569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7317937319
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 2.0312878042 12200463
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.7616580747
MESH:D007889 Leiomyoma Raloxifene 4.9616973256
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.2016294345 17596541
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 1.2512878042
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 1.8316984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.3312151625
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.9817228818
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 1.2419555203 11884234
MESH:D008881 Migraine Disorders Valproic Acid 3.4718803445 18765137
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 6.2815863610
MESH:D009101 Multiple Myeloma Raloxifene 3.7116497877
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.458888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3517596541
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.3412213967
MESH:D009232 Myxoma Raloxifene 6.2816343187
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.7214600291
MESH:D009436 Neural Tube Defects Valproic Acid 3.378888407 16359493
MESH:D010024 Osteoporosis Raloxifene 3.6115775268 19059307 17882678
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.6915579764 17893378 17823083 15758505
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.1511578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.9712520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 4.0718163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 11.6611222880 11118676 11399792 11896295
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 11.6620603192
MESH:D011471 Prostatic Neoplasms Raloxifene 3.5416536755 16220300 15731164
MESH:D011537 Pruritus Ethinyl Estradiol 3.9415861022 16919318
MESH:D019310 Pseudolymphoma Valproic Acid 5.2612752131 11422049
MESH:D011693 Purpura Raloxifene 6.2815770314
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.3518990726
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.6419155313
MESH:D012559 Schizophrenia Valproic Acid 2.1015737665 19110320
MESH:D012640 Seizures Valproic Acid 2.9914763951 11738929 3137016 16876388 11044598 1511512 15475178 17978042
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.2016192470
MESH:D013088 Spermatocele Ethinyl Estradiol 4.6616709447
MESH:D016135 Spinal Dysraphism Valproic Acid 4.0919490988
MESH:D013226 Status Epilepticus Valproic Acid 5.2612833885
MESH:D020521 Stroke Raloxifene 4.1516837676
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.0811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5215669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.6212697716
MESH:D013978 Tibial Fractures Raloxifene 5.9319048282
MESH:D014178 Translocation, Genetic Valproic Acid 5.9617262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 5.153119515
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 2.9317572228
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.208888407
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8014692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.3212125929
MESH:D054556 Venous Thromboembolism Raloxifene 5.9316837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.9714671159 15869587
MESH:D014846 Vulvar Neoplasms Raloxifene 6.2816343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.9715886252
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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