AutismKB 2.0

Annotation Detail for TSHZ3


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Basic Information Top
Gene Symbol:TSHZ3 ( FLJ54422,KIAA1474,TSH3,ZNF537 )
Gene Full Name: teashirt zinc finger homeobox 3
Band: 19q12
Quick LinksEntrez ID:57616; OMIM: NA; Uniprot ID:TSH3_HUMAN; ENSEMBL ID: ENSG00000121297; HGNC ID: 30700
Relate to Another Database: SFARIGene; denovo-db
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Related Diseases/Disorders Top
No data
No data
Desease Name
NEUROLOGICAL
Cognitive performance
Desease Name
Cognitive performance
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TSHZ3 mRNAdecreases expression 20382639
D007501 Iron Iron deficiency results in increased expression of TSHZ3 mRNAincreases expression 20368581
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 6.5416640825
MESH:D000544 Alzheimer Disease Iron 3.0816563566 16640825
MESH:D000740 Anemia Iron 4.8716434484 16566752
MESH:D018798 Anemia, Iron-Deficiency Iron 5.1517375513 16569441 17163184 17147795 17162259
MESH:D000756 Anemia, Sideroblastic Iron 5.3616910769
MESH:D001145 Arrhythmias, Cardiac Iron 4.8716604332
MESH:D001260 Ataxia Telangiectasia Iron 6.3415336622
MESH:D050197 Atherosclerosis Iron 3.9616632123 16640825
MESH:D001321 Autistic Disorder Iron 2.7617352947
MESH:D001424 Bacterial Infections Iron 6.0816640825
MESH:D009202 Cardiomyopathies Iron 4.3416640825
MESH:D002311 Cardiomyopathy, Dilated Iron 3.5816604332
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0420889678
MESH:D003110 Colonic Neoplasms Iron 2.9516640825
MESH:D003920 Diabetes Mellitus Iron 4.9216604332 16640825
MESH:D003922 Diabetes Mellitus, Type 1 Iron 3.4716506275
MESH:D003924 Diabetes Mellitus, Type 2 Iron 3.1716506275
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1620426865
MESH:D005234 Fatty Liver Iron 4.6316640825
MESH:D005621 Friedreich Ataxia Iron 6.1916604332 16640825
MESH:D006432 Hemochromatosis Iron 4.8316640825 17053826 17236123 16574947 16604332 17255318
MESH:D006486 Hemosiderosis Iron 6.2816604332
MESH:D006525 Hepatitis, Viral, Human Iron 6.5416640825
MESH:D006527 Hepatolenticular Degeneration Iron 5.7017182432
MESH:D006529 Hepatomegaly Iron 5.0816890145
MESH:D015658 HIV Infections Iron 3.8816597321
MESH:D007006 Hypogonadism Iron 4.7316640825
MESH:D007037 Hypothyroidism Iron 5.8516640825
MESH:D019189 Iron Metabolism Disorders Iron 5.6417163184
MESH:D020961 Lewy Body Disease Iron 6.1916563566
MESH:D008103 Liver Cirrhosis Iron 3.9516640825
MESH:D008108 Liver Diseases, Alcoholic Iron 5.7717207112 16737972
MESH:D008113 Liver Neoplasms Iron 3.2816640825 20302851
MESH:D008175 Lung Neoplasms Iron 2.6716640825
MESH:D008268 Macular Degeneration Iron 4.2116640825
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 6.7417086897
MESH:D009181 Mycoses Iron 6.5416640825
MESH:D017202 Myocardial Ischemia Iron 4.8516604332
MESH:D015428 Myocardial Reperfusion Injury Iron 4.6516604332
MESH:D009404 Nephrotic Syndrome Iron 4.9817178036
MESH:D019636 Neurodegenerative Diseases Iron 4.6816604332 17296847
MESH:D010003 Osteoarthritis Iron 4.2316640825
MESH:D010024 Osteoporosis Iron 4.1316648989 16640825
MESH:D010212 Papilloma Iron 5.2412065085
MESH:D020447 Parasomnias Iron 7.0917352947
MESH:D010300 Parkinson Disease Iron 3.4616640825 16563566
MESH:D010900 Pituitary Diseases Iron 6.7416604332
MESH:D011041 Poisoning Iron 4.8916604332
MESH:D017119 Porphyria Cutanea Tarda Iron 5.6616640825
MESH:D011225 Pre-Eclampsia Iron 4.8116640825
MESH:D011528 Protozoan Infections Iron 7.0916640825
MESH:D012148 Restless Legs Syndrome Iron 4.9116930377
MESH:D012878 Skin Neoplasms Iron 3.6512065085
MESH:D013398 Sudden Infant Death Iron 6.3416640825
MESH:D014376 Tuberculosis Iron 4.3616597321
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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