AutismKB 2.0

Annotation Detail for LRFN1


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Basic Information Top
Gene Symbol:LRFN1 ( KIAA1484,SALM2 )
Gene Full Name: leucine rich repeat and fibronectin type III domain containing 1
Band: 19q13.2
Quick LinksEntrez ID:57622; OMIM: 612807; Uniprot ID:LRFN1_HUMAN; ENSEMBL ID: ENSG00000128011; HGNC ID: 29290
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of LRFN1 mRNAaffects cotreatment|increases expression 17183730
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of LRFN1 mRNAaffects cotreatment|increases expression 17183730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 4.378875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.4819490988
MESH:D000550 Amblyopia Valproic Acid 6.3017688650
MESH:D001008 Anxiety Disorders Valproic Acid 3.9817497229
MESH:D001321 Autistic Disorder Valproic Acid 1.9818775368 18316065 18940202 20603192 16609825 18558336 18396377 18985861 17688650 17507914 15238991 19232924 18177632 17157402 19460635
MESH:D001714 Bipolar Disorder Valproic Acid 3.2820046352 17594078
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.698888407
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8420734317
MESH:D019465 Craniofacial Abnormalities Valproic Acid 1.918888407 16575769 17688650
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 2.2719641884 1733752
MESH:D004421 Dystonia Valproic Acid 4.661851702
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.923659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 4.983922381 16628512
MESH:D004827 Epilepsy Valproic Acid 3.1420417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 4.066426943 7562514 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 5.067750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.953659116
MESH:D005234 Fatty Liver Valproic Acid 3.8519224547 14986274
MESH:D005315 Fetal Diseases Valproic Acid 5.9616575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.8118558336 8888407
MESH:D006849 Hydrocephalus Valproic Acid 5.7517688650
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 5.3916612254
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.2116294345 17596541
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 5.3317228818
MESH:D008881 Migraine Disorders Valproic Acid 3.5318765137 18803445
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.588888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.4017596541
MESH:D009436 Neural Tube Defects Valproic Acid 3.4216359493 8888407
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 4.7120603192
MESH:D019310 Pseudolymphoma Valproic Acid 5.6111422049 12752131
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.7819155313
MESH:D012559 Schizophrenia Valproic Acid 2.1119110320 15737665
MESH:D012640 Seizures Valproic Acid 3.051511512 16876388 3137016 17978042 11044598 14763951 11738929 15475178
MESH:D016135 Spinal Dysraphism Valproic Acid 4.1719490988
MESH:D013226 Status Epilepticus Valproic Acid 5.6112833885
MESH:D014178 Translocation, Genetic Valproic Acid 6.3017262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 5.413119515
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.418888407
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018