AutismKB 2.0

Annotation Detail for PTMS


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Basic Information Top
Gene Symbol:PTMS ( ParaT )
Gene Full Name: parathymosin
Band: 12p13
Quick LinksEntrez ID:5763; OMIM: 168440; Uniprot ID:PTMS_HUMAN; ENSEMBL ID: ENSG00000159335; HGNC ID: 9629
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of PTMS proteinaffects expression 20106945
D000638 Amiodarone Amiodarone affects the expression of PTMS mRNAaffects expression 19483382
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PTMS mRNAaffects expression 16483693
D001553 Benzbromarone Benzbromarone affects the expression of PTMS mRNAaffects expression 19483382
D001554 Benzene [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of PTMS mRNAaffects cotreatment|decreases expression 17905399
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of PTMS mRNAdecreases expression 20106945
C095105 bexarotene bexarotene results in increased expression of PTMS mRNAincreases expression 16648578
D019256 Cadmium Chloride Cadmium Chloride results in increased expression of PTMS mRNAincreases expression 12760830
D002994 Clofibrate Clofibrate affects the expression of PTMS mRNAaffects expression 19483382
D002995 Clofibric Acid Clofibric Acid affects the expression of PTMS mRNAaffects expression 17602206
D003024 Clozapine Clozapine results in increased expression of PTMS mRNAincreases expression 14647396
D016572 Cyclosporine Cyclosporine results in decreased expression of PTMS mRNAdecreases expression 20106945
D004391 Dust Dust results in decreased expression of PTMS mRNAdecreases expression 17805423
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of PTMS mRNAaffects expression 17555576
D005001 Ethionine Ethionine affects the expression of PTMS mRNAaffects expression 19483382
D005419 Flavonoids Flavonoids results in decreased expression of PTMS mRNAdecreases expression 18035473
D019833 Genistein Genistein results in decreased expression of PTMS mRNAdecreases expression 16705744
D006220 Haloperidol Haloperidol results in increased expression of PTMS mRNAincreases expression 14647396
D006861 Hydrogen Peroxide Hydrogen Peroxide results in decreased expression of PTMS mRNAdecreases expression 12419474
D007657 Ketone Bodies Ketone Bodies results in increased expression of PTMS mRNAincreases expression 16807920
C030957 methylmercury II [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of PTMS mRNAaffects cotreatment|decreases expression 17905399
D009853 Omeprazole Omeprazole affects the expression of PTMS mRNAaffects expression 19483382
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of PTMS mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid affects the expression of PTMS mRNAaffects expression 19483382
D011441 Propylthiouracil Propylthiouracil affects the expression of PTMS mRNAaffects expression 19483382
D012643 Selenium Selenium results in increased expression of PTMS mRNAincreases expression 19244175
D013629 Tamoxifen Tamoxifen affects the expression of PTMS mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of PTMS mRNAdecreases expression 16054898
D013853 Thioacetamide Thioacetamide affects the expression of PTMS mRNAaffects expression 19483382
D014241 Trichloroethylene [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of PTMS mRNAaffects cotreatment|decreases expression 17905399
D014810 Vitamin E Vitamin E results in increased expression of PTMS mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.2614745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.5711752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.2818287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.6617505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.8618653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 6.6120127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.6114692618
MESH:D000230 Adenocarcinoma Genistein 6.6111473722
MESH:D000236 Adenoma Benzo(a)pyrene 2.496695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.9716434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.9716835633
MESH:D000380 Agranulocytosis Clozapine 4.7812649775 14617031 16160616
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7111748828
MESH:D000741 Anemia, Aplastic Benzene 4.1611369114 17661222 14761424
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.8019183758
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.5620041841 18057881 18218290
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.1911256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.4915885639
MESH:D001281 Atrial Fibrillation Amiodarone 3.7019698954 18651412
MESH:D001321 Autistic Disorder Haloperidol 2.7718080171 19368416
MESH:D001778 Blood Coagulation Disorders Amiodarone 53.3819483382
MESH:D001778 Blood Coagulation Disorders Benzbromarone 53.3819483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 53.3819483382
MESH:D001778 Blood Coagulation Disorders Ethionine 53.3819483382
MESH:D001778 Blood Coagulation Disorders Omeprazole 53.3819483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 53.3819483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 53.3819483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 53.3812125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 53.3819483382
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5915746008
MESH:D001855 Bone Marrow Diseases Benzene 4.9516183116
MESH:D001943 Breast Neoplasms Benzene 3.5817162533 11921183
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 3.5820146248 17474063
MESH:D001943 Breast Neoplasms bexarotene 3.5816344269 16818667
MESH:D001943 Breast Neoplasms Genistein 3.5816873071 16541309 17200150
MESH:D001943 Breast Neoplasms Tamoxifen 3.5816202921 20859285 19487384 18629630 19155303 19103187 19189212 18984771 20135344 19200415 19189210 19289846 17440819 19244106 16873071 21152245 19084267 20065188 15668708 18855134 15565566 19066611 21138602 18997820 19410462 20005174 19115204 18425577 11161223 16818667 18351453 20390343 17049068 18821012 19011961 19288272 17893378 16273361 18815881 17242785 19142967 17261762 20544844 19059307 19221464
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.5820435547
MESH:D001943 Breast Neoplasms Trichloroethylene 3.5815986119
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.6616050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.5816835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.2319066611
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 8.3812907637 21507988 12619106
MESH:D006528 Carcinoma, Hepatocellular Benzbromarone 8.381701930
MESH:D006528 Carcinoma, Hepatocellular Genistein 8.3816924424
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 8.3816924424
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 8.3817997003
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.1316247446
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 1.9720419170
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.3717572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2116120746 18670907 18850075
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.8015710769 19225199
MESH:D002318 Cardiovascular Diseases Genistein 6.8916332659
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 6.8916936243
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.8018974383
MESH:D002375 Catalepsy Haloperidol 4.6315215559 1977408
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 6.221399818
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 6.2212371664
MESH:D002637 Chest Pain Omeprazole 4.8215447763
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.7716835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 8.7718291259
MESH:D002779 Cholestasis Cyclosporine 12.1619486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.1616919318 15861022 17681005 11677210 16105132 17333356 17110522
MESH:D002779 Cholestasis pirinixic acid 12.1619176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.998697196 12621046 15340226 15668235 16354765
MESH:D003072 Cognition Disorders Clozapine 4.6917123785
MESH:D003092 Colitis Selenium 3.5117936198
MESH:D003110 Colonic Neoplasms Genistein 2.2417182828
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8317141729 14669216
MESH:D019465 Craniofacial Abnormalities Benzene 3.6615643154
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.6620055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Vitamin E 3.6619769572
MESH:D016757 Death, Sudden, Cardiac Haloperidol 4.5820210726
MESH:D003704 Dementia Haloperidol 4.3311575062
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0919031437
MESH:D003872 Dermatitis Benzene 4.4915902427
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3018249437
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 6.7816402076
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 6.7816647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.7817107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.2419279558
MESH:D006970 Disorders of Excessive Somnolence Clozapine 5.2715331141
MESH:D056486 Drug-Induced Liver Injury Amiodarone 11.1115265979 18218290
MESH:D056486 Drug-Induced Liver Injury Selenium 11.1115131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.1120420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 11.1112963478
MESH:D056486 Drug-Induced Liver Injury Trichloroethylene 11.117120509
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.5611462148
MESH:D004381 Duodenal Ulcer Omeprazole 4.0621218061 17151854 16613094 15991576
MESH:D050171 Dyslipidemias Clofibrate 8.4316707586
MESH:D050171 Dyslipidemias Clozapine 8.4316402076
MESH:C538011 Eales disease Vitamin E 4.429068938
MESH:D004487 Edema pirinixic acid 5.7212083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.7211000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.6218230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.0612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.0619031437
MESH:D004714 Endometrial Hyperplasia Genistein 4.3116402032
MESH:D016889 Endometrial Neoplasms Genistein 6.9311473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 6.9317893378 19155303 20544844 16202921
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.7810568697 9294722
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 1.9416530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8111564622
MESH:D005218 Fat Necrosis Thioacetamide 5.4416456712
MESH:D005234 Fatty Liver Amiodarone 27.4714986274
MESH:D005234 Fatty Liver Clofibrate 27.4719224547
MESH:D005234 Fatty Liver Cyclosporine 27.4719224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 27.4715345470
MESH:D005234 Fatty Liver pirinixic acid 27.4719236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 27.4719224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.0716709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1811858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.2514745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.9019069698
MESH:D005355 Fibrosis Cyclosporine 7.5712639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 7.5720067830
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.948708960
MESH:D005909 Glioblastoma Genistein 3.0816598420
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3110696789
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 10.2520471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.2510048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 10.2516080930
MESH:D006333 Heart Failure pirinixic acid 6.3820558911
MESH:D006333 Heart Failure Selenium 6.3817162251
MESH:D006402 Hematologic Diseases Benzene 4.4016183116
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.1415720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0911000095
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.3217276928 18665440 15929193
MESH:D006505 Hepatitis Thioacetamide 3.9516456712
MESH:D006529 Hepatomegaly Amiodarone 12.8315265979
MESH:D006529 Hepatomegaly pirinixic acid 12.8319176532 16221962 19772884 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 12.8315340226 12621046 16120746
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6016490937 16863852
MESH:D019584 Hot Flashes Vitamin E 3.6914716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.7616354765 8697196 18606429 15340226 16959395
MESH:D006937 Hypercholesterolemia Amiodarone 3.629751232 8137927
MESH:D006943 Hyperglycemia pirinixic acid 2.9420558911
MESH:D006948 Hyperkinesis Clozapine 4.6316046005
MESH:D006973 Hypertension Benzene 7.9817940673
MESH:D006973 Hypertension Cyclosporine 7.9810903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.9818670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.5416569931 16945680
MESH:D007037 Hypothyroidism Amiodarone 10.7018020914 17991464
MESH:D007037 Hypothyroidism Propylthiouracil 10.708137927 18031379
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2012013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.3117937319
MESH:D007249 Inflammation Flavonoids 7.4517296493
MESH:D007249 Inflammation Tamoxifen 7.4519457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.4512878042 12200463
MESH:D007251 Influenza, Human Selenium 10.0116624496
MESH:D007251 Influenza, Human Vitamin E 10.0116624496
MESH:D007333 Insulin Resistance pirinixic acid 2.4516306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.0916580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.1615604871
MESH:D007674 Kidney Diseases Cadmium Chloride 9.2416962696
MESH:D007674 Kidney Diseases Cyclosporine 9.2418776723 8314463 10903974
MESH:D007674 Kidney Diseases Vitamin E 9.2412488133
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 9.2016518626
MESH:D007676 Kidney Failure, Chronic Selenium 9.2016518626
MESH:D007680 Kidney Neoplasms Cyclosporine 6.5512371664
MESH:D007680 Kidney Neoplasms Tamoxifen 6.5518625569
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 3.8719248655
MESH:D007938 Leukemia Benzene 6.1715935818 18335105 17119257 14694614
MESH:D007938 Leukemia Genistein 6.1718980019 17468513
MESH:D007951 Leukemia, Myeloid Benzene 4.0717506065
MESH:D015470 Leukemia, Myeloid, Acute Benzene 2.6519478238
MESH:D008064 Lipidoses Amiodarone 12.0915342952 17567588
MESH:D008064 Lipidoses Clozapine 12.0917567588
MESH:D008064 Lipidoses Tamoxifen 12.0917567588 15342952
MESH:D008106 Liver Cirrhosis, Experimental Genistein 8.2517823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 8.2515474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 8.2518564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 8.2512878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 8.2515716488 15316131 12557150 17292413 16511523 15334695 12679928 18295389 15465738 17355460 18615449 11682029 18606216 16098781 18458672 17629604 16097051 15095483 14739098 17127702 15362042 18380797 12891558 15288473 16248980 11172339 18395095 15474484 12175628 15078482 10677585 16343077 12531686 16126171 18031379 15288472 15075984 18032466 11481614 18263696 18416461 16489207 12085344 17050028 15158331
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 8.2516169303
MESH:D008107 Liver Diseases Thioacetamide 2.6415158337 18374380 16337175
MESH:D017114 Liver Failure, Acute Thioacetamide 4.0717276928 15633222 12479984 15313186
MESH:D008113 Liver Neoplasms Aflatoxin B1 16.569163691 15890375 18177683 2125692
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 16.5620195826 21137059
MESH:D008113 Liver Neoplasms Clofibric Acid 16.5617602206
MESH:D008113 Liver Neoplasms pirinixic acid 16.5620007298 16377806 15890375
MESH:D008113 Liver Neoplasms Tamoxifen 16.5616684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 16.5616984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 12.788603461
MESH:D008114 Liver Neoplasms, Experimental Benzene 12.7812562636
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 12.7812151625
MESH:D008114 Liver Neoplasms, Experimental Trichloroethylene 12.787955063
MESH:D008133 Long QT Syndrome Amiodarone 3.3717391786 11989578 15350150
MESH:D008171 Lung Diseases Amiodarone 6.9012587719
MESH:D008171 Lung Diseases Vitamin E 6.9016863852
MESH:D017563 Lung Diseases, Interstitial Amiodarone 10.5218516814
MESH:D017563 Lung Diseases, Interstitial Benzene 10.5214698565
MESH:D008175 Lung Neoplasms Aflatoxin B1 10.1314755239
MESH:D008175 Lung Neoplasms Benzene 10.1312562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 10.1318569708 20064080 20135361 17053015 18816296 20869020 20464547 18520028 6695378
MESH:D008175 Lung Neoplasms bexarotene 10.1317849452
MESH:D008175 Lung Neoplasms Tamoxifen 10.1318625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 10.1311884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 10.1311062179
MESH:D008223 Lymphoma Benzene 3.5417584886 17119257
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.8711161223
MESH:D015674 Mammary Neoplasms, Animal Benzene 9.1412562636
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 9.1419428831
MESH:D008325 Mammary Neoplasms, Experimental Benzene 16.9511921183
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 16.9519196722 15591091 19196723
MESH:D008325 Mammary Neoplasms, Experimental Genistein 16.9514578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Selenium 16.9515318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 16.9514580682 16827153 11731420 19196723 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 4.2619453300
MESH:D008545 Melanoma Tamoxifen 1.8419393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.9015990972
MESH:D001523 Mental Disorders Clozapine 7.4416856516
MESH:D001523 Mental Disorders Haloperidol 7.4416856516
MESH:D008654 Mesothelioma Selenium 2.6815107826
MESH:D024821 Metabolic Syndrome X Clozapine 4.1819142101
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5016801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.9816381670
MESH:D009101 Multiple Myeloma Benzene 3.4717119195
MESH:D009135 Muscular Diseases pirinixic acid 3.2316239165
MESH:D009181 Mycoses Amiodarone 4.6217974566 12754197
MESH:D009203 Myocardial Infarction Genistein 5.2817141266
MESH:D009203 Myocardial Infarction pirinixic acid 5.2819151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8012213967
MESH:D015428 Myocardial Reperfusion Injury Genistein 7.6917141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.6916411023
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.4419393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4219410462
MESH:D009369 Neoplasms Benzo(a)pyrene 7.5311141357
MESH:D009369 Neoplasms pirinixic acid 7.5317405874
MESH:D009369 Neoplasms Trichloroethylene 7.5311911487
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 9.9919196722
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 9.9919189210 19200415 19196722
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.1617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.0518481113 19348381
MESH:D009421 Nervous System Malformations Genistein 8.7216427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.7214600291
MESH:D009436 Neural Tube Defects Benzene 3.4915643154
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 4.669802331
MESH:D009765 Obesity Clozapine 4.4619142110 18515891
MESH:D009765 Obesity pirinixic acid 4.4620558911
MESH:D009784 Occupational Diseases Benzene 3.9415612468 17479406 15576619 15935809 17119257 17178637 16737584 15913788 15727169
MESH:D010024 Osteoporosis Genistein 3.0819401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.8316169203
MESH:D010051 Ovarian Neoplasms Benzene 4.8712562636
MESH:D010051 Ovarian Neoplasms Genistein 4.8719005980
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4311578682
MESH:D010212 Papilloma Hydrogen Peroxide 3.8212065085
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9612520081
MESH:D010954 Plasmacytoma Selenium 4.6015087411
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2918163543
MESH:D011230 Precancerous Conditions Cyclosporine 2.9912371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.9111399792 11896295 11222880 11118676
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.1217292933
MESH:D011471 Prostatic Neoplasms Genistein 2.1215378649 15256057 16925846
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.1215067354
MESH:D011471 Prostatic Neoplasms Vitamin E 2.1215084515
MESH:D011537 Pruritus Ethinyl Estradiol 3.0316919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.1316882103
MESH:D011595 Psychomotor Agitation Haloperidol 4.6811575062
MESH:D011618 Psychotic Disorders Clozapine 8.5015331141
MESH:D011618 Psychotic Disorders Haloperidol 8.5011575062
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.7512832656 12490602 11597910
MESH:D015427 Reperfusion Injury pirinixic acid 2.2519058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5718990726
MESH:D012559 Schizophrenia Clozapine 3.9511151749 11763009 19369910 20580759 20521320 17667964 16141801 20168265 20521326 20107430 20452607 18855531 17123785 17726453 18806925
MESH:D012559 Schizophrenia Haloperidol 3.9518513383 20107430 1830565 19369910
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.8018724381
MESH:D012871 Skin Diseases Vitamin E 2.3718709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 8.6719755658 10029692
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 8.6712065085
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.6716192470
MESH:D013088 Spermatocele Ethinyl Estradiol 10.6116709447
MESH:D013088 Spermatocele Tamoxifen 10.6116709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.7619457130
MESH:D013272 Stomach Diseases Omeprazole 4.3318545984
MESH:D013274 Stomach Neoplasms Benzene 2.5012562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.502093021 20155912
MESH:D013276 Stomach Ulcer Amiodarone 6.7618087811
MESH:D013276 Stomach Ulcer Omeprazole 6.7616755016 18237397 17977527 11906479 10750652 15991576
MESH:D020521 Stroke Vitamin E 3.3016517955
MESH:D013610 Tachycardia Amiodarone 4.0211238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 9.6519225199
MESH:D017180 Tachycardia, Ventricular Haloperidol 9.6520210726
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9215669648
MESH:D013953 Thymus Neoplasms Benzene 4.6810850423
MESH:D013959 Thyroid Diseases Amiodarone 11.1019731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 11.1012697716
MESH:D013964 Thyroid Neoplasms Propylthiouracil 3.4715710170
MESH:D013971 Thyrotoxicosis Amiodarone 4.5919584973 18020914
MESH:D016171 Torsades de Pointes Amiodarone 3.9117467628 11989578
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 4.6317053015
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 4.638653321 16712894 17572228
MESH:D014594 Uterine Neoplasms Benzene 8.6912562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.6914692618
MESH:D014605 Uveitis Cyclosporine 3.701336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3112125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2915869587 14671159
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9615886252
MESH:D015430 Weight Gain Clozapine 4.2320521320 17502770 20564506 16141801 16402076 20107430
MESH:D015431 Weight Loss Clozapine 4.8017933447
MESH:D014985 Xerophthalmia Cyclosporine 4.1617120751
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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