AutismKB 2.0

Annotation Detail for KIAA1522


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Basic Information Top
Gene Symbol:KIAA1522 ( - )
Gene Full Name: KIAA1522
Band: 1p35.1
Quick LinksEntrez ID:57648; OMIM: NA; Uniprot ID:K1522_HUMAN; ENSEMBL ID: ENSG00000162522; HGNC ID: 29301
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C006632 arsenic trioxide arsenic trioxide results in increased expression of KIAA1522 mRNAincreases expression 20458559
D019833 Genistein Genistein results in decreased expression of KIAA1522 mRNAdecreases expression 16705744
D014810 Vitamin E Vitamin E results in decreased expression of KIAA1522 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma arsenic trioxide 4.8211798837 19825857
MESH:D000230 Adenocarcinoma Genistein 4.8211473722
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 4.1516206674
MESH:D001943 Breast Neoplasms Genistein 2.4817200150 16541309 16873071
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.8611589617
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.5816050911
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 3.3315073043 14691202 15553829 16217749 11135700
MESH:D006528 Carcinoma, Hepatocellular Genistein 3.3316924424
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.7419014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.5712490120
MESH:D002318 Cardiovascular Diseases Genistein 3.5916332659
MESH:D003110 Colonic Neoplasms Genistein 2.3417182828
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8720501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.7712609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.8110525206
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.8119769572
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.6315213294
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 2.5616647724
MESH:C538011 Eales disease Vitamin E 5.579068938
MESH:D004714 Endometrial Hyperplasia Genistein 5.3316402032
MESH:D016889 Endometrial Neoplasms Genistein 3.6311473722
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.3912903497
MESH:D005234 Fatty Liver arsenic trioxide 3.7715073043
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.8516904648
MESH:D005909 Glioblastoma Genistein 3.5216598420
MESH:D006330 Heart Defects, Congenital Vitamin E 3.1816080930
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.8216490937 16863852
MESH:D019584 Hot Flashes Vitamin E 4.8414716179
MESH:D007251 Influenza, Human Vitamin E 5.0816624496
MESH:D007674 Kidney Diseases Vitamin E 3.0312488133
MESH:D007938 Leukemia arsenic trioxide 7.0615070760
MESH:D007938 Leukemia Genistein 7.0617468513 18980019
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.2812560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 5.0516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.7514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.2419077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1916467208 19850784 20471514 16968895 17050201
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.4819075265 15622746 16112521 19225113 16823087 16331271 17649720 16966277 17107899 16330433 9834237 12018890 19035177 15336539 15213294 17869043 11468182 17217047 16891316 15748426 19642359 11161223 17712046 12679006 12712474
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.9416882451
MESH:D008106 Liver Cirrhosis, Experimental Genistein 2.7417823541
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 2.7416169303
MESH:D008113 Liver Neoplasms arsenic trioxide 2.4714682389
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 2.9820377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.6915213294
MESH:D008171 Lung Diseases Vitamin E 3.4516863852
MESH:D008175 Lung Neoplasms arsenic trioxide 2.6311798837 19825857
MESH:D008175 Lung Neoplasms Vitamin E 2.6311062179
MESH:D008325 Mammary Neoplasms, Experimental Genistein 3.2012929590 14578162
MESH:D009101 Multiple Myeloma arsenic trioxide 3.4119417148 15949261 14977855 11468182 19549372
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.5418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3616105982 16882451
MESH:D009203 Myocardial Infarction Genistein 3.0017141266
MESH:D015428 Myocardial Reperfusion Injury Genistein 4.0017141266
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.5416624393
MESH:D009421 Nervous System Malformations Genistein 4.6116427766
MESH:D009436 Neural Tube Defects arsenic trioxide 3.3810525206
MESH:D010024 Osteoporosis Genistein 3.5019401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 4.6116169203
MESH:D010051 Ovarian Neoplasms arsenic trioxide 5.3319769630 12452020 16624393
MESH:D010051 Ovarian Neoplasms Genistein 5.3319005980
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6415580305
MESH:D010235 Paraganglioma arsenic trioxide 4.6919927285
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.5519131511
MESH:D011471 Prostatic Neoplasms Genistein 2.5516925846 15256057 15378649
MESH:D011471 Prostatic Neoplasms Vitamin E 2.5515084515
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.5416646077
MESH:D012871 Skin Diseases Vitamin E 2.5218709164
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D020521 Stroke Vitamin E 3.8816517955
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.4319014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.7015213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 2.6120435036 11780464 12973940 12845720
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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