AutismKB 2.0

Annotation Detail for USP29


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Basic Information Top
Gene Symbol:USP29 ( HOM-TES-84/86,MGC163266,MGC163270 )
Gene Full Name: ubiquitin specific peptidase 29
Band: 19q13.43
Quick LinksEntrez ID:57663; OMIM: 609546; Uniprot ID:UBP29_HUMAN; ENSEMBL ID: ENSG00000131864; HGNC ID: 18563
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D005038 Ethylnitrosourea Ethylnitrosourea results in increased mutagenesis of USP29 exonincreases mutagenesis 16300676
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of USP29 mRNAaffects binding|decreases expression|increases activity 19710929
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.7218653653
MESH:D000236 Adenoma Ethylnitrosourea 3.976695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.3716434500
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.7019483382
MESH:D001927 Brain Diseases Ethylnitrosourea 5.3914991843
MESH:D001932 Brain Neoplasms Ethylnitrosourea 4.8015144691 16651633 16357521 16436596 18412241
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 4.0416003739
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 7.0517160924
MESH:D002779 Cholestasis pirinixic acid 3.1919176532
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.6118249437
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 7.0518357618
MESH:D004487 Edema pirinixic acid 3.0212083418
MESH:D005234 Fatty Liver pirinixic acid 3.3120131406 19236843
MESH:D005909 Glioblastoma Ethylnitrosourea 4.1216436596
MESH:D005910 Glioma Ethylnitrosourea 3.6418412241 16651633 16357521
MESH:D006333 Heart Failure pirinixic acid 2.8120558911
MESH:D006529 Hepatomegaly pirinixic acid 3.7619176532 18467677 19772884 16221962
MESH:D006943 Hyperglycemia pirinixic acid 3.6920558911
MESH:D007333 Insulin Resistance pirinixic acid 2.9316306350
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 4.3617379185
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008113 Liver Neoplasms pirinixic acid 1.9520007298 15890375 16377806
MESH:D008175 Lung Neoplasms Ethylnitrosourea 2.6316271038 17703301 16019985 6695378
MESH:D008223 Lymphoma Ethylnitrosourea 4.2815790496
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 5.8115375218
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 3.8018041768 10838139 10767621
MESH:D008579 Meningioma Ethylnitrosourea 7.0517943659
MESH:D009135 Muscular Diseases pirinixic acid 4.2716239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.3019151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.3316411023
MESH:D009369 Neoplasms pirinixic acid 2.1417405874
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 5.1616707424
MESH:D009442 Neurilemmoma Ethylnitrosourea 6.3017160924 16003739 16651423
MESH:D009765 Obesity pirinixic acid 1.9020558911
MESH:D009837 Oligodendroglioma Ethylnitrosourea 7.0517160924
MESH:D015427 Reperfusion Injury pirinixic acid 2.5819058328
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 6.0515790496
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018