AutismKB 2.0

Annotation Detail for GPAM


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Basic Information Top
Gene Symbol:GPAM ( GPAT,GPAT1,KIAA1560,MGC26846 )
Gene Full Name: glycerol-3-phosphate acyltransferase, mitochondrial
Band: 10q25.2
Quick LinksEntrez ID:57678; OMIM: 602395; Uniprot ID:GPAT1_HUMAN; ENSEMBL ID: ENSG00000119927; HGNC ID: 24865
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY4FS-8phosphatidylglycerol biosynthesis II (non-plastidic)
TRIGLSYN-PWYtriacylglycerol biosynthesis
PWY-5667CDP-diacylglycerol biosynthesis I
Pathway IDPathway Name
hsa00561Glycerolipid metabolism
hsa00564Glycerophospholipid metabolism
hsa01100Metabolic pathways
Pathway IDPathway Name
Metabolism of lipids and lipoproteins
Pathway IDPathway Name
200045Validated targets of C-MYC transcriptional activation
No data
Pathway IDPathway Name
500875Triglyceride Biosynthesis
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of GPAM mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of GPAM mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in increased expression of GPAM mRNAincreases expression 11264010
D000638 Amiodarone Amiodarone results in increased expression of GPAM mRNAincreases expression 19224547
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GPAM mRNAaffects expression 16483693
C065179 atorvastatin atorvastatin inhibits the reaction [Fructose results in increased expression of GPAM mRNA]decreases reaction|increases expression 19053045
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GPAM mRNAaffects cotreatment|decreases expression 18164116
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of GPAM mRNAdecreases expression 20382639
D002104 Cadmium Cadmium results in increased expression of GPAM mRNAincreases expression 17066326
D019256 Cadmium Chloride Cadmium Chloride results in increased expression of GPAM mRNAincreases expression 17066326
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of GPAM mRNAaffects expression 17484886
D020111 Chlorodiphenyl (54% Chlorine) Chlorodiphenyl (54% Chlorine) results in increased expression of GPAM mRNAincreases expression 18178546
D002994 Clofibrate Clofibrate results in increased expression of GPAM mRNAincreases expression 19224547
D003474 Curcumin Curcumin inhibits the reaction [Dietary Fats results in increased expression of GPAM mRNA]decreases reaction|increases expression 19297423
D003474 Curcumin Curcumin results in decreased expression of GPAM mRNAdecreases expression 19297423
D016572 Cyclosporine Cyclosporine results in decreased expression of GPAM mRNAdecreases expression 20106945
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GPAM mRNAaffects cotreatment|increases expression 16054899
D003907 Dexamethasone EGF protein inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GPAM mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D003907 Dexamethasone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GPAM mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D004041 Dietary Fats Curcumin inhibits the reaction [Dietary Fats results in increased expression of GPAM mRNA]decreases reaction|increases expression 19297423
D004041 Dietary Fats Dietary Fats results in increased expression of GPAM mRNAincreases expression 17932310
19297423
18042831
D004041 Dietary Fats PPARGC1B protein promotes the reaction [Dietary Fats results in increased expression of GPAM mRNA]increases expression|increases reaction 17932310
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GPAM mRNAaffects cotreatment|decreases expression 18164116
C045651 epigallocatechin gallate epigallocatechin gallate results in decreased expression of GPAM mRNAdecreases expression 16988119
D004958 Estradiol Estradiol results in decreased expression of GPAM mRNAdecreases expression 20106945
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GPAM mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of GPAM mRNAdecreases expression 15576828
D011345 Fenofibrate Fenofibrate results in increased expression of GPAM mRNAincreases expression 16707586
D005485 Flutamide Flutamide results in decreased expression of GPAM mRNAdecreases expression 17702527
D005632 Fructose atorvastatin inhibits the reaction [Fructose results in increased expression of GPAM mRNA]decreases reaction|increases expression 19053045
D005632 Fructose Fructose results in increased expression of GPAM mRNAincreases expression 19053045
18346472
C056933 fumonisin B1 fumonisin B1 results in decreased expression of GPAM mRNAdecreases expression 16221962
D019266 Iron, Dietary Iron, Dietary affects the expression of GPAM mRNAaffects expression 15637178
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GPAM mRNAaffects cotreatment|increases expression 16054899
D015056 1-Methyl-3-isobutylxanthine EGF protein inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GPAM mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D015056 1-Methyl-3-isobutylxanthine Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GPAM mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D007657 Ketone Bodies Ketone Bodies results in decreased expression of GPAM mRNAdecreases expression 16807920
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of GPAM mRNAdecreases expression 16847310
C041786 palm oil palm oil results in increased expression of GPAM mRNAincreases expression 18042831
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of GPAM mRNAincreases expression 17681415
D010634 Phenobarbital Phenobarbital results in increased expression of GPAM mRNAincreases expression 19270015
C006253 pirinixic acid ACAA1B protein inhibits the reaction [pirinixic acid results in increased expression of GPAM mRNA]decreases reaction|increases expression 19772884
C006253 pirinixic acid pirinixic acid results in increased expression of GPAM mRNAincreases expression 11798191
18301758
15302862
17426115
16221962
19772884
15777286
C006253 pirinixic acid PPARA protein affects the reaction [pirinixic acid results in increased expression of GPAM mRNA]affects reaction|increases expression 15777286
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GPAM mRNAaffects cotreatment|increases expression 16054899
C089730 rosiglitazone EGF protein inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GPAM mRNA]affects cotreatment|decreases reaction|increases expression 16054899
C089730 rosiglitazone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GPAM mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D012402 Rotenone Rotenone results in decreased expression of GPAM mRNAdecreases expression 17702527
C009250 sevoflurane sevoflurane affects the expression of GPAM mRNAaffects expression 15967596
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GPAM mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GPAM mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of GPAM mRNAdecreases expression 18295293
C423915 TO-901317 TO-901317 results in increased expression of GPAM mRNAincreases expression 15302862
C052342 topiramate topiramate results in decreased expression of GPAM mRNAdecreases expression 16979414
D014280 Triglycerides GPAM protein results in increased chemical synthesis of Triglyceridesincreases chemical synthesis 19053045
D014635 Valproic Acid Valproic Acid results in increased expression of GPAM mRNAincreases expression 19224547
D015032 Zinc Zinc affects the expression of GPAM mRNAaffects expression 17181878
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 11.716195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 11.7115322242 11752688 14514962
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 11.718875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.5419490988
MESH:D000138 Acidosis Ammonium Chloride 3.1318287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5017505938
MESH:D000169 Acrodermatitis Zinc 4.9717202136 17190629 16889938
MESH:D055371 Acute Lung Injury Lipopolysaccharides 7.7311850527 18653653
MESH:D055371 Acute Lung Injury pirinixic acid 7.7318653653
MESH:D000230 Adenocarcinoma Estradiol 3.8011473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 3.8014692618
MESH:D000236 Adenoma beta-Naphthoflavone 6.0219389873
MESH:D000236 Adenoma Diethylnitrosamine 6.0210737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 21.3117162532 19061943 16434500 17620307 18056438 19052882
MESH:D018248 Adenoma, Liver Cell Phenobarbital 21.3117620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 21.3116434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 21.3116835633
MESH:D000437 Alcoholism topiramate 4.6919331489 17925516 18552399
MESH:D019973 Alcohol-Related Disorders Curcumin 4.6417887948
MESH:D000544 Alzheimer Disease Curcumin 6.1315590663
MESH:D000544 Alzheimer Disease rosiglitazone 6.1319621015
MESH:D000544 Alzheimer Disease Zinc 6.1317119284 16325427 16410023 16580781
MESH:D000550 Amblyopia Valproic Acid 4.7917688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.5811748828
MESH:D000755 Anemia, Sickle Cell Zinc 4.4916916123
MESH:D000799 Angioedema Acetaminophen 3.4010982225
MESH:D001008 Anxiety Disorders Valproic Acid 3.2317497229
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.4320041841 18218290 18057881
MESH:D001161 Arteriosclerosis Dietary Fats 8.5115238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 8.5111256880
MESH:D001169 Arthritis, Experimental Dexamethasone 6.4717659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.4715885639
MESH:D001172 Arthritis, Rheumatoid Curcumin 2.6316807698
MESH:D001249 Asthma epigallocatechin gallate 4.9616516891
MESH:D001249 Asthma Zinc 4.9617085522
MESH:D050197 Atherosclerosis Cadmium 6.1815687053
MESH:D050197 Atherosclerosis Curcumin 6.1818704882
MESH:D001281 Atrial Fibrillation Amiodarone 3.5818651412 19698954
MESH:D001321 Autistic Disorder Acetaminophen 1.8618445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8618316065 15238991 17688650 17157402 17507914 18396377 20603192 19232924 18558336 16609825 18985861 19460635 18177632 18940202 18775368
MESH:D001327 Autoimmune Diseases Curcumin 9.7119761891
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 9.7119761891
MESH:D001714 Bipolar Disorder Valproic Acid 2.8517594078 20046352
MESH:D001778 Blood Coagulation Disorders Amiodarone 18.8319483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 18.8319483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 18.8319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 18.8312125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.0815746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.088888407
MESH:D001930 Brain Injuries Zinc 4.2717109824
MESH:D002545 Brain Ischemia Curcumin 3.9016770732
MESH:D001932 Brain Neoplasms Curcumin 3.5717596214
MESH:D001943 Breast Neoplasms Curcumin 2.1716243823 18593918 18462866 19250217
MESH:D001943 Breast Neoplasms Dietary Fats 2.1720435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.1717474063
MESH:D001943 Breast Neoplasms Estradiol 2.1717289903 19861407 18497071 17018787 12948864 14630087 16675129 17261762
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.1720435547
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0316111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.3618705752 15700767 15673190 15721981 16227642 16097048 3786805 16124888 16192424 16011737 16050911 10355542
MESH:D002277 Carcinoma Curcumin 7.1618593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.1616835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 10.2816705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 10.283084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 10.2818788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 10.2818971187 19919837 10737359 17978847 18665156 16830150 20512989 17138121 19418558 10672840 3581430 16935385 19335982 16288022 21159647 20214788 18978308 16878318 16698587 3084413 11831363 16502159 16779866 20727157 20432363 19701751 18494052 17173139 20007298 19052882 16681979 19539802 18691550 16569478 18056438 18506893 20101231 19171122 19822196 16328049 17162532 16540662 19107877 20514400 19383236 17055752 19394651 18393292 20084675 19208518 20524982 18210153 20935162 18788625 18785209 19519916 17428255 16807293 17761372
MESH:D006528 Carcinoma, Hepatocellular Estradiol 10.2816924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 10.2820935162 17173139 6705139 1701930 20007298
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.8218414057
MESH:D002294 Carcinoma, Squamous Cell Curcumin 4.5818462866
MESH:D002294 Carcinoma, Squamous Cell Zinc 4.5816543248
MESH:D006332 Cardiomegaly atorvastatin 6.3818360054
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.3816120746 18850075 18670907
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.7319225199 15710769
MESH:D002318 Cardiovascular Diseases Zinc 3.3616936243
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.6518974383
MESH:D002386 Cataract Acetaminophen 2.3210977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 22.4620889678
MESH:D002471 Cell Transformation, Neoplastic Cadmium 22.4617332340
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 22.461399818
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 22.4612371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 22.4617174075 2727394 21159647 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 22.4618566989
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.834080065
MESH:D002659 Child Development Disorders, Pervasive topiramate 5.8515650499
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 5.8520734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.1219052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.1216835633
MESH:D002779 Cholestasis Cyclosporine 11.4919486331
MESH:D002779 Cholestasis Ethinyl Estradiol 11.4917681005 17110522 16919318 16105132 17333356 15861022 11677210
MESH:D002779 Cholestasis pirinixic acid 11.4919176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.9112621046 8697196 16354765 15340226 15668235
MESH:D003092 Colitis Curcumin 3.7616804969 16782535 18200517
MESH:D003103 Coloboma Curcumin 4.1618809619
MESH:D003110 Colonic Neoplasms Curcumin 3.7116340194 19359593
MESH:D003110 Colonic Neoplasms Dexamethasone 3.7115824018
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7014669216 17141729
MESH:D016510 Corneal Neovascularization Curcumin 4.4718497527
MESH:D003324 Coronary Artery Disease atorvastatin 3.9816368305
MESH:D003327 Coronary Disease Fructose 4.1918504504
MESH:D019465 Craniofacial Abnormalities Dexamethasone 4.9717728286
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.9710048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Valproic Acid 4.978888407 17688650 16575769
MESH:D019465 Craniofacial Abnormalities Zinc 4.9719302082
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.5918551238
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 3.0112438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2218249437
MESH:D003920 Diabetes Mellitus rosiglitazone 8.3817446233
MESH:D003920 Diabetes Mellitus Zinc 8.3816479319
MESH:D003921 Diabetes Mellitus, Experimental Fructose 4.1418603373
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 19.0918403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 19.0920387270
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 19.0916988119
MESH:D003924 Diabetes Mellitus, Type 2 Fructose 19.0918603373
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 19.0912642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 19.0917107852
MESH:D003924 Diabetes Mellitus, Type 2 topiramate 19.0916979414
MESH:D003928 Diabetic Nephropathies Curcumin 7.8418204486
MESH:D003928 Diabetic Nephropathies Estradiol 7.8419279558
MESH:D003967 Diarrhea Dexamethasone 3.307237001
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 23.0221346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 23.0211421492 11287661 17522070 11834606 16393943 11461765 12392966 18071297 15968718 19416960 19164858 16227642 12540782 10915739 14550746 14986274 11743745 12958197 10774834 16177239 12594235 16109766 12153990 12705907 11739529 16081117 19370779 19085960 19923254 19739265 15619225 14725611 2444490 16781746 19420014 10663392 16485898 11529661 17906064 17562736 18713872
MESH:D056486 Drug-Induced Liver Injury Amiodarone 23.0215265979 18218290
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 23.0215968718 19336974 19085960 6884620 17522070 15998439 9327722 7179309 10915739 3786805 7440962 4309450 16227642 7120509 21278145 6623471 16177239 3732212 2869522 11566570 15027814 10092053
MESH:D056486 Drug-Induced Liver Injury Chlorodiphenyl (54% Chlorine) 23.0217851650
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 23.0219107877
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 23.0216221962
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 23.0220420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 23.021733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6619426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.4411462148
MESH:D004381 Duodenal Ulcer Curcumin 3.6417351913
MESH:D050171 Dyslipidemias Clofibrate 12.8416707586
MESH:D050171 Dyslipidemias Dietary Fats 12.8418367378
MESH:D050171 Dyslipidemias Fenofibrate 12.8416707586
MESH:D004421 Dystonia Phenobarbital 9.111851702
MESH:D004421 Dystonia Valproic Acid 9.111851702
MESH:D004485 Eczema Dexamethasone 4.0512438553
MESH:D004487 Edema Dexamethasone 17.6219703484
MESH:D004487 Edema perfluorooctanoic acid 17.6212083418 17259670
MESH:D004487 Edema pirinixic acid 17.6212083418
MESH:D004487 Edema rosiglitazone 17.6212083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 17.6212711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.4615322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 2.7812538720
MESH:D016889 Endometrial Neoplasms Estradiol 6.8211473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Fenofibrate 6.8216569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.6510568697 9294722
MESH:D019446 Endotoxemia Lipopolysaccharides 3.9717637181 15821434 15328337
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 9.393659116
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 9.3917275665 3659116
MESH:D004828 Epilepsies, Partial Phenobarbital 8.523922381 11558140
MESH:D004828 Epilepsies, Partial Valproic Acid 8.523922381 16628512
MESH:D004827 Epilepsy Phenobarbital 9.8620417680
MESH:D004827 Epilepsy topiramate 9.8619148780
MESH:D004827 Epilepsy Valproic Acid 9.8618234410 20417680
MESH:D004832 Epilepsy, Absence Phenobarbital 7.666401628
MESH:D004832 Epilepsy, Absence Valproic Acid 7.666426943 6254150 7562514
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 9.907750514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 9.907750514
MESH:D004833 Epilepsy, Temporal Lobe topiramate 5.8316499746
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 9.053659116
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 9.053659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6816302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.2420426865
MESH:D004938 Esophageal Neoplasms Zinc 4.2416543248
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.6911564622
MESH:D005234 Fatty Liver Amiodarone 60.2914986274
MESH:D005234 Fatty Liver Carbon Tetrachloride 60.2961145 12795759 16239168 15959796 17595544 16045604 19224547 12631006
MESH:D005234 Fatty Liver Clofibrate 60.2919224547
MESH:D005234 Fatty Liver Curcumin 60.2919297423
MESH:D005234 Fatty Liver Cyclosporine 60.2919224547
MESH:D005234 Fatty Liver Dietary Fats 60.2918296743 19551842 17967931 19004024
MESH:D005234 Fatty Liver Diethylnitrosamine 60.2920387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 60.2915345470
MESH:D005234 Fatty Liver Fructose 60.2919196556 18395287 18641190
MESH:D005234 Fatty Liver pirinixic acid 60.2920131406 19236843
MESH:D005234 Fatty Liver rosiglitazone 60.2919196556
MESH:D005234 Fatty Liver Valproic Acid 60.2919224547 14986274
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0411858732
MESH:D005315 Fetal Diseases Valproic Acid 4.4516575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.7218558336 8888407
MESH:D005334 Fever Lipopolysaccharides 3.6411852909 9205823
MESH:D005355 Fibrosis Carbon Tetrachloride 29.0518705752
MESH:D005355 Fibrosis Curcumin 29.0518705752
MESH:D005355 Fibrosis Cyclosporine 29.0512639820 12168785
MESH:D005355 Fibrosis Dietary Fats 29.0518296743
MESH:D005355 Fibrosis Fructose 29.0518504504
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 29.0520067830
MESH:D005756 Gastritis Acetaminophen 9.7016983495
MESH:D005756 Gastritis Zinc 9.7017241300
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.2718462866
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.798708960
MESH:D005909 Glioblastoma Curcumin 3.1917596214
MESH:D018149 Glucose Intolerance Fructose 4.9319165636
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1510696789
MESH:D006130 Growth Disorders Zinc 3.6817217573
MESH:D006258 Head and Neck Neoplasms Curcumin 3.3618462866 18829502
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.1010048152 11294989
MESH:D006333 Heart Failure atorvastatin 10.4516360360
MESH:D006333 Heart Failure pirinixic acid 10.4520558911
MESH:D006333 Heart Failure Zinc 10.4517162251
MESH:D006335 Heart Injuries Zinc 5.3317074742
MESH:D016481 Helicobacter Infections Zinc 4.1417241300
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.9915720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.0116366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9511000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.1919900420 19110552
MESH:D006527 Hepatolenticular Degeneration Zinc 4.2717276780
MESH:D006529 Hepatomegaly Amiodarone 28.3015265979
MESH:D006529 Hepatomegaly fumonisin B1 28.3016221962
MESH:D006529 Hepatomegaly perfluorooctanoic acid 28.303609246
MESH:D006529 Hepatomegaly Phenobarbital 28.3016109766
MESH:D006529 Hepatomegaly pirinixic acid 28.3016221962 19176532 19772884 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 28.3015340226 12621046 16120746
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.6217701891
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.917520565
MESH:D006558 Herpes Genitalis Estradiol 4.5915709030
MESH:D019584 Hot Flashes Estradiol 3.3217088409
MESH:D006849 Hydrocephalus Valproic Acid 4.4317688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.618697196 18606429 15340226 16959395 16354765
MESH:D006930 Hyperalgesia Acetaminophen 11.2216870215
MESH:D006930 Hyperalgesia perfluorooctanoic acid 11.2212083418
MESH:D006930 Hyperalgesia rosiglitazone 11.2212083418
MESH:D017588 Hyperandrogenism Flutamide 5.0215356085
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.1016899240
MESH:D006937 Hypercholesterolemia Amiodarone 18.728137927 9751232
MESH:D006937 Hypercholesterolemia atorvastatin 18.7211583720
MESH:D006937 Hypercholesterolemia Curcumin 18.7218704882
MESH:D006937 Hypercholesterolemia Dietary Fats 18.7221332399
MESH:D006943 Hyperglycemia pirinixic acid 2.8120558911
MESH:D006946 Hyperinsulinism Fructose 4.5418360027 18563319 15752949 19008412 14757778
MESH:D006949 Hyperlipidemias Dietary Fats 8.2421332399
MESH:D006949 Hyperlipidemias Fructose 8.2415752949
MESH:D006938 Hyperlipoproteinemia Type II atorvastatin 4.8216238680
MESH:D006973 Hypertension atorvastatin 14.5117042910
MESH:D006973 Hypertension Cyclosporine 14.5110903974
MESH:D006973 Hypertension Dexamethasone 14.5117042910
MESH:D006973 Hypertension Fructose 14.5114568997 14573337 14633139 16843071 19008412
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 14.5118670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.6715338365
MESH:D015228 Hypertriglyceridemia Fructose 10.1319342510 19799862
MESH:D015228 Hypertriglyceridemia Triglycerides 10.1316979400 16238453
MESH:D007021 Hypospadias Ethinyl Estradiol 3.3916569931 16945680
MESH:D007037 Hypothyroidism Amiodarone 4.0917991464 18020914
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 5.0018306037
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.0712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.2017937319
MESH:D007249 Inflammation atorvastatin 28.5316908763
MESH:D007249 Inflammation Curcumin 28.5316956363 18403477 17151092
MESH:D007249 Inflammation Dexamethasone 28.538960868 11099482
MESH:D007249 Inflammation Dietary Fats 28.5320412841
MESH:D007249 Inflammation Diethylnitrosamine 28.5318785209
MESH:D007249 Inflammation Lipopolysaccharides 28.5317255318 17237260 17963957 12878042 9205823
MESH:D007249 Inflammation perfluorooctanoic acid 28.5312083418
MESH:D007249 Inflammation rosiglitazone 28.5312083418
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 28.5312200463 12878042
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.0318200517 18596194
MESH:D007333 Insulin Resistance Dietary Fats 20.1711836018 18457598
MESH:D007333 Insulin Resistance Estradiol 20.1716393666 16627594
MESH:D007333 Insulin Resistance Fructose 20.1714573337 14757778 18563319 19799862 18981581 19342510 18057795 19008412 19586609 17133782 14633139
MESH:D007333 Insulin Resistance pirinixic acid 20.1716306350
MESH:D007333 Insulin Resistance rosiglitazone 20.1716306350
MESH:D007414 Intestinal Neoplasms Curcumin 3.8510783313
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.2317255318
MESH:D007511 Ischemia Zinc 4.2116584753
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.9516580747
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 5.0018306037
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0015604871
MESH:D007674 Kidney Diseases Acetaminophen 20.5312587719 15629191
MESH:D007674 Kidney Diseases Cadmium 20.5316962696 16322080 16226777
MESH:D007674 Kidney Diseases Cadmium Chloride 20.5316962696
MESH:D007674 Kidney Diseases Cyclosporine 20.538314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 20.5315618244
MESH:D007674 Kidney Diseases Zinc 20.5316960431
MESH:D007676 Kidney Failure, Chronic Zinc 4.0416518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 10.3516705839
MESH:D007680 Kidney Neoplasms Cyclosporine 10.3512371664
MESH:D007680 Kidney Neoplasms Estradiol 10.3515610895
MESH:D007859 Learning Disorders sevoflurane 4.3519212262
MESH:D007889 Leiomyoma Curcumin 4.1718555241
MESH:D007938 Leukemia Curcumin 3.0218462866
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 3.8216106398
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.0716294345 17596541
MESH:D015458 Leukemia, T-Cell Curcumin 4.3516106398
MESH:D007970 Leukopenia Lipopolysaccharides 4.2715821434
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 4.808812269
MESH:D008064 Lipidoses Amiodarone 3.2015342952 17567588
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 13.7211408273 16221502 16943688 17157831 17334410 21278145 16239168 17174718 11903743
MESH:D008103 Liver Cirrhosis Dietary Fats 13.7218296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 13.7220032147 18407596 18522880 18665156 19638242
MESH:D008103 Liver Cirrhosis Phenobarbital 13.7221047994
MESH:D008106 Liver Cirrhosis, Experimental atorvastatin 19.3417347453
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 19.3412958196 14620537 15123356 17708605 17525996 18472094 18187930 17557913 15362042 18412020 12667390 12741479 18418968 18251166 18420326 18210741 18481824 18006644 15876570 17805973 11481614 18376398 12609069 17698563 18395095 12898905 17640975 15730626 12445421 16015684 20821823 12389079 16027843 15925388 17766677 12649538 16192424 16248980 15996030 18395914 17631135 15931870 18429990 15818738 18156304 16638106 18263696 14748882 14716833 17922224 15959796 12445418 17944888 12586293 16097048 18472332 14724832 17761835 17900296 16136751 18279442 12632514 18339082 17869086 10355542 17481882 17721639 12546737 12632512 17714472 16033810 15673190 18705752 18054572 15057751 15338365 13678700 18277467 18205269 15052691 18166357 17976157 16011737 18317297 17565644 15370692 15893842 15650968 17823541 14716496 14512876 12666154 16116963
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 19.3418705752 18006644 17355460
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 19.3416718785
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 19.3417481882
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 19.3414716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Fenofibrate 19.3415474484
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 19.3412878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 19.3415474484
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 19.3415980055 17347453
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 19.3412878042
MESH:D008107 Liver Diseases Acetaminophen 11.1312969438 11587558 19014921 16610002 19460945 12587719 19784758 16611625
MESH:D008107 Liver Diseases Carbon Tetrachloride 11.1315720792 17285989 16964402 15830285 16246199
MESH:D008107 Liver Diseases Curcumin 11.1316956363
MESH:D008107 Liver Diseases Diethylnitrosamine 11.1317034775
MESH:D008107 Liver Diseases Phenobarbital 11.1319363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.7415123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.1717185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.1716899240 14706259
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 22.7919389873 21295105
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 22.7919294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 22.7920118626 20101389 19642983 19499222 18978307 15175105 19833225 19255062 19850985 12771043 20434301 19690152 19551842 19254457 2422723 19996281 20583210 18977376 21167192 19638242 19427195 20452335 19090486 21278145 19073162 18644402 2862719 12112319 16942905 19294768 15885732 20137499 21047994 18754104 21071580 18648771 20501860 19426721 20405173 20492335 19256749 19812893 9163691 10737359
MESH:D008113 Liver Neoplasms Fenofibrate 22.7918978307
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 22.7914757943 18709148
MESH:D008113 Liver Neoplasms Phenobarbital 22.7915975961 19812893 19482888 8742319 19073162 21047994
MESH:D008113 Liver Neoplasms pirinixic acid 22.7920007298 16377806 15890375
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 22.7916984957
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 19.7918164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 19.7912014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 19.7921159647 16267830 17854601 18775883 2563599 19519916 16842330 19539802 9362446 19009564 18308698 18079962 18093689 18544905 19004024 17942915 19126423 18253720 3124819 18164116 18282651 17174075
MESH:D008114 Liver Neoplasms, Experimental Fenofibrate 19.7918775883 18253720
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 19.7917172636 1399818 2563599 18308698 6150874
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 19.7912151625
MESH:D008133 Long QT Syndrome Amiodarone 3.2515350150 17391786 11989578
MESH:D008171 Lung Diseases Amiodarone 3.0812587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 9.8018516814
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 9.8017228818
MESH:D055370 Lung Injury Lipopolysaccharides 3.5921114838
MESH:D008175 Lung Neoplasms Curcumin 4.3818462866 19359593 16243823
MESH:D008175 Lung Neoplasms Dexamethasone 4.3815824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 4.3820512841 20970405 6695378 21163286
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.3819555203 11884234
MESH:D008223 Lymphoma Curcumin 3.2818462866
MESH:D016399 Lymphoma, T-Cell Curcumin 4.2716173963
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 8.5011408345 11807958 17203775 16891317
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 8.5016827153
MESH:D008325 Mammary Neoplasms, Experimental Zinc 8.5012773700
MESH:D020149 Manganese Poisoning Estradiol 4.0419453300
MESH:D008545 Melanoma Curcumin 3.5918462866 17885582
MESH:D008545 Melanoma epigallocatechin gallate 3.5911746506 17992120
MESH:D008546 Melanoma, Experimental Acetaminophen 3.1519513568
MESH:D008569 Memory Disorders Curcumin 8.6017263510
MESH:D008569 Memory Disorders sevoflurane 8.6019212262
MESH:D024821 Metabolic Syndrome X Fructose 8.8718497449 19165636 16815490 17098227 17261469
MESH:D024821 Metabolic Syndrome X rosiglitazone 8.8717261469
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.3516801185
MESH:D008881 Migraine Disorders topiramate 7.0216942474 18803445 18759728 18765137
MESH:D008881 Migraine Disorders Valproic Acid 7.0218803445 18765137
MESH:D009101 Multiple Myeloma Curcumin 6.5619372569
MESH:D009101 Multiple Myeloma Dexamethasone 6.5615744524 15867202 16118317
MESH:D009134 Muscular Atrophy, Spinal Curcumin 11.2117962980
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 11.2117962980
MESH:D009135 Muscular Diseases atorvastatin 9.3516239165
MESH:D009135 Muscular Diseases pirinixic acid 9.3516239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.648888407
MESH:D009181 Mycoses Amiodarone 4.4612754197 17974566
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 6.719809623
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 6.7117596541
MESH:D009203 Myocardial Infarction pirinixic acid 1.9619151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.1516810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.1516411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.0417484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.4318551238
MESH:D009361 Neoplasm Invasiveness Curcumin 3.9618495463
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.399029167 3581430
MESH:D009369 Neoplasms pirinixic acid 1.7417405874
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 4.1012497104
MESH:D009389 Neovascularization, Pathologic Estradiol 3.3017289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0017954296
MESH:D009404 Nephrotic Syndrome atorvastatin 8.5219348381
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.5219348381 18481113
MESH:D009410 Nerve Degeneration Rotenone 3.5515790535 17356569 18619942
MESH:D009421 Nervous System Malformations Estradiol 8.1111399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.1114600291
MESH:D009423 Nervous System Neoplasms Curcumin 5.1918462866
MESH:D009436 Neural Tube Defects Valproic Acid 2.848888407 16359493
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.0218514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.0220387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6820387270
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 10.669802331
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 10.669802331
MESH:D009765 Obesity Curcumin 9.6719297423
MESH:D009765 Obesity Dietary Fats 9.6717217161 18674790 19632207 11836018 21332399 16723640 18457598 20518802 20132043
MESH:D009765 Obesity Fructose 9.6718585860 17707055
MESH:D009765 Obesity pirinixic acid 9.6720558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.0616049721 12819281
MESH:D010018 Osteomalacia Phenobarbital 3.9317016548
MESH:D010024 Osteoporosis Curcumin 3.2018719352
MESH:D010051 Ovarian Neoplasms Curcumin 4.4818462866 19020741
MESH:D010051 Ovarian Neoplasms Estradiol 4.4819401270
MESH:D010146 Pain Acetaminophen 2.0616870215
MESH:D010190 Pancreatic Neoplasms Curcumin 7.6719401701 19196508 17440100
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 7.6716540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 7.6716965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2911578682
MESH:D010300 Parkinson Disease Rotenone 2.8119114014 16140633 18191903 16412576 11535288 18619942 15451049 19232380 11445065
MESH:D020734 Parkinsonian Disorders Rotenone 3.7015795934 15574749 15927086 18197244
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8112520081
MESH:D016491 Peripheral Vascular Diseases Cadmium 4.9515687053
MESH:D011014 Pneumonia Lipopolysaccharides 4.1212224865 11605937
MESH:D011085 Polycystic Ovary Syndrome Flutamide 4.6215356085
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1518163543
MESH:D011230 Precancerous Conditions Cyclosporine 13.1812371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 13.182563599
MESH:D011230 Precancerous Conditions Phenobarbital 13.182563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.3021297632
MESH:D011225 Pre-Eclampsia Zinc 3.8417114810
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 13.8117132714
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 13.8111399792 11118676 11222880 11896295
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 13.8120603192
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.5020887781
MESH:D011471 Prostatic Neoplasms Cadmium 1.9517075824
MESH:D011471 Prostatic Neoplasms Curcumin 1.9515129424 10851300 18226269 12497104 11398177 18156803 18769126
MESH:D011471 Prostatic Neoplasms Estradiol 1.9516740699
MESH:D011471 Prostatic Neoplasms Flutamide 1.953169114
MESH:D011471 Prostatic Neoplasms Zinc 1.9516606632 16517595 16700911 12429649
MESH:D011537 Pruritus Ethinyl Estradiol 2.8916919318 15861022
MESH:D019310 Pseudolymphoma Phenobarbital 10.7312752131
MESH:D019310 Pseudolymphoma Valproic Acid 10.7312752131 11422049
MESH:D011565 Psoriasis Cyclosporine 2.0716882103
MESH:D011656 Pulmonary Emphysema Curcumin 4.1519168576
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.6811597910 12490602 12832656
MESH:D015427 Reperfusion Injury pirinixic acid 2.1719058328
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 7.9918379247 10666014
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 7.9911700416 18379247
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.4410835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4318990726
MESH:D012162 Retinal Degeneration Zinc 3.8016584753
MESH:D012208 Rhabdomyosarcoma Valproic Acid 3.7819155313
MESH:D012509 Sarcoma Curcumin 3.7418462866
MESH:D012559 Schizophrenia Valproic Acid 2.0119110320 15737665
MESH:D012640 Seizures 2,4-dinitrotoluene 11.7118551238
MESH:D012640 Seizures Phenobarbital 11.714039156 11442880 16876388 3137016
MESH:D012640 Seizures topiramate 11.7116499746
MESH:D012640 Seizures Valproic Acid 11.711511512 15475178 11044598 16876388 3137016 11738929 14763951 17978042
MESH:D003294 Seizures, Febrile Phenobarbital 4.396407741
MESH:D018805 Sepsis Curcumin 3.7218389075
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.6518724381
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 1.8416192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.5016709447
MESH:D016135 Spinal Dysraphism Valproic Acid 3.4519490988
MESH:D013226 Status Epilepticus Valproic Acid 4.1012833885
MESH:D013272 Stomach Diseases Dexamethasone 3.8915472012
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7518456281
MESH:D013276 Stomach Ulcer Amiodarone 9.9518087811
MESH:D013276 Stomach Ulcer Curcumin 9.9516631530 19188055
MESH:D013276 Stomach Ulcer Dexamethasone 9.9515138204
MESH:D013610 Tachycardia Amiodarone 3.8811238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 3.7819225199
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.7915821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7915669648
MESH:D013959 Thyroid Diseases Amiodarone 10.5919731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 10.5912697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 6.107505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 6.101399818
MESH:D013971 Thyrotoxicosis Amiodarone 4.4418020914 19584973
MESH:D013978 Tibial Fractures Estradiol 4.2519048282
MESH:D014062 Tongue Neoplasms Zinc 4.0216543248
MESH:D016171 Torsades de Pointes Amiodarone 3.7611989578 17467628
MESH:D014178 Translocation, Genetic Valproic Acid 4.7917262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.093119515
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 4.6316049721
MESH:D001749 Urinary Bladder Neoplasms Curcumin 4.6318593936
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.228888407
MESH:D014565 Urogenital Neoplasms Curcumin 4.8318462866
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.8810091137
MESH:D014581 Urticaria Acetaminophen 2.5810982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.8914692618
MESH:D014605 Uveitis Cyclosporine 10.301336536
MESH:D014605 Uveitis Dexamethasone 10.301336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1512125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.1514671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8115886252
MESH:D015430 Weight Gain Dietary Fats 3.3816723640
MESH:D014985 Xerophthalmia Cyclosporine 4.0017120751
Pathway ID Pathway Name
KEGG:00561 Glycerolipid metabolism
KEGG:00564 Glycerophospholipid metabolism
KEGG:01100 Metabolic pathways
REACT:22258 Metabolism of lipids and lipoproteins
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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