Annotation Detail for ZDBF2
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C472791 |
3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid |
3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of ZDBF2 mRNA | decreases expression | 16788091
|
| D016572 |
Cyclosporine |
Cyclosporine results in increased expression of ZDBF2 mRNA | increases expression | 20106945
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ZDBF2 mRNA | affects binding|increases activity|increases expression | 19710929
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.64 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.22 | 16434500 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.63 | 19483382 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
2.82 | 12371664 |
| MESH:D002779 |
Cholestasis |
|
Cyclosporine |
8.86 | 19486331 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
8.86 | 19176532 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.59 | 18249437 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.96 | 12083418 |
| MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
9.21 | 19224547 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
9.21 | 20131406 19236843 |
| MESH:D005355 |
Fibrosis |
|
Cyclosporine |
3.79 | 12168785 12639820 |
| MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
4.96 | 8708960 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.78 | 20558911 |
| MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
5.16 | 15720958 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.64 | 19772884 19176532 16221962 18467677 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.63 | 20558911 |
| MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.23 | 10903974 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.90 | 16306350 |
| MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
5.31 | 15604871 |
| MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
2.56 | 8314463 18776723 10903974 |
| MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
3.12 | 12371664 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.94 | 15890375 16377806 20007298 |
| MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.65 | 16801185 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.16 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.29 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.29 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.12 | 17405874 |
| MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
5.31 | 17954296 |
| MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.70 | 19348381 18481113 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.89 | 20558911 |
| MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.64 | 12371664 |
| MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.34 | 16882103 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.56 | 19058328 |
| MESH:D014605 |
Uveitis |
|
Cyclosporine |
4.85 | 1336536 |
| MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
5.31 | 17120751 |
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