AutismKB 2.0

Annotation Detail for MAGEE1


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Basic Information Top
Gene Symbol:MAGEE1 ( DAMAGE,HCA1,KIAA1587 )
Gene Full Name: melanoma antigen family E, 1
Band: Xq13.3
Quick LinksEntrez ID:57692; OMIM: 300759; Uniprot ID:MAGE1_HUMAN; ENSEMBL ID: ENSG00000198934; HGNC ID: 24934
Relate to Another Database: SFARIGene; denovo-db
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of MAGEE1 mRNAdecreases expression 18648102
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of MAGEE1 mRNAaffects expression 17484886
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 3.003712494
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 6.091440618 11289319
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.5416192424 16227642 16050911 15673190 18705752 15721981 10355542 15700767 16011737 16124888 16097048 3786805
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 3.153581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 3.1518788625
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.867296757
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 3.087505956
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 3.5119486331 9022650
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.558970840 8156756 2524372 18759878 11298694 12868966 14531868 11906362
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 4.103621924 2952479
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 4.2418692083 7440962 18289764 6679447 11289319 9653073 6482804 18648102 9022650 16192314 1440618 8291058 9328219
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 4.2410915739 9327722 6884620 4309450 7120509 19085960 7179309 15968718 10092053 17522070 19336974 21278145 6623471 16177239 3732212 2869522 15027814 16227642 15998439 7440962 11566570 3786805
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.193581430
MESH:D005234 Fatty Liver Carbon Tetrachloride 3.7216239168 12631006 17595544 12795759 16045604 15959796 19224547 61145
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 6.096705139
MESH:D005355 Fibrosis Carbon Tetrachloride 4.2218705752
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.647505956
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 11.576705139
MESH:D006505 Hepatitis Carbon Tetrachloride 11.5719900420 19110552
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 5.4216899240
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.7015034207
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.8515338365
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 6.099022650 8074119
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.406582329
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 3.0411408273 17334410 17174718 11903743 21278145 16943688 17157831 16239168 16221502
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.4715034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 1.7613678700 17869086 17976157 17481882 17721639 12632514 20821823 15925388 12586293 17761835 12741479 15338365 15730626 17900296 12667390 17823541 18418968 14620537 11481614 16033810 18156304 18376398 15650968 16248980 15996030 17557913 18205269 15370692 16116963 14748882 18317297 18277467 17565644 12389079 15893842 16097048 14724832 16015684 17640975 18054572 16192424 14716496 12632512 18472332 17631135 18412020 16027843 14716833 15876570 12898905 15959796 18006644 18279442 18472094 12445421 17922224 12958196 18395914 18429990 17805973 17766677 12649538 18263696 16638106 12546737 18210741 15052691 16136751 16011737 12445418 15123356 17714472 15673190 18251166 15362042 12666154 17525996 17708605 18339082 14512876 18187930 15818738 10355542 15931870 15057751 17698563 18166357 17944888 12609069 18395095 18705752 18420326 18481824
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.1716964402 15720792 17285989 15830285 16246199
MESH:D017093 Liver Failure Carbon Tetrachloride 4.9315123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 4.2016899240 14706259
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 2.3619294768
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 6.86598648 1399818 3712494 6587162
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 6.8612014681 15583823
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.623581430
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.216679447
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.926482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 6.093988306
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 4.247296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.546228378
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.743692021
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.266587162 6582329 1399818 7505956 3712494
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.428074119
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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