Annotation Detail for CCNB1IP1
Basic Information Top
| Gene Symbol: | CCNB1IP1 ( C14orf18,HEI10 ) |
|---|---|
| Gene Full Name: | cyclin B1 interacting protein 1 |
| Band: | 14q11.2 |
| Quick Links | Entrez ID:57820; OMIM: 608249; Uniprot ID:CIP1_HUMAN; ENSEMBL ID: ENSG00000100814; HGNC ID: 19437 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of CCNB1IP1 mRNA | decreases expression | 20106945 |
| C053541 | bicalutamide | bicalutamide results in increased expression of CCNB1IP1 mRNA | increases expression | 15638997 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of CCNB1IP1 mRNA | decreases expression | 20678512 |
| C051890 | irinotecan | CCNB1IP1 protein results in increased susceptibility to irinotecan | increases response to substance | 16734730 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000230 | Adenocarcinoma | Benzo(a)pyrene | 2.06 | 20127859 20464547 | |
| MESH:D000236 | Adenoma | Benzo(a)pyrene | 2.86 | 6695378 | |
| MESH:D017544 | Aortic Aneurysm, Abdominal | Benzo(a)pyrene | 4.64 | 19183758 | |
| MESH:D001862 | Bone Resorption | bisphenol A | 4.29 | 11985600 | |
| MESH:D001943 | Breast Neoplasms | Benzo(a)pyrene | 2.14 | 20146248 17474063 | |
| MESH:D001943 | Breast Neoplasms | bisphenol A | 2.14 | 17123778 | |
| MESH:D002278 | Carcinoma in Situ | bisphenol A | 5.62 | 17123778 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Benzo(a)pyrene | 2.13 | 20419170 | |
| MESH:D003110 | Colonic Neoplasms | irinotecan | 2.64 | 17725105 17287894 | |
| MESH:D015179 | Colorectal Neoplasms | irinotecan | 2.36 | 17454858 16391804 18509181 17159606 16303861 15273666 18259882 | |
| MESH:D004938 | Esophageal Neoplasms | Benzo(a)pyrene | 2.08 | 16530937 | |
| MESH:D006330 | Heart Defects, Congenital | Benzo(a)pyrene | 2.83 | 20471113 | |
| MESH:D007333 | Insulin Resistance | bisphenol A | 3.53 | 16393666 | |
| MESH:D008113 | Liver Neoplasms | Benzo(a)pyrene | 2.15 | 21137059 20195826 | |
| MESH:D008175 | Lung Neoplasms | Benzo(a)pyrene | 1.57 | 18569708 20869020 18816296 20064080 18520028 20464547 6695378 17053015 20135361 | |
| MESH:D009062 | Mouth Neoplasms | Benzo(a)pyrene | 3.50 | 16381670 | |
| MESH:D052016 | Mucositis | irinotecan | 5.64 | 17159606 | |
| MESH:D009362 | Neoplasm Metastasis | irinotecan | 3.30 | 18259882 | |
| MESH:D009369 | Neoplasms | Benzo(a)pyrene | 2.33 | 11141357 | |
| MESH:D009421 | Nervous System Malformations | bisphenol A | 4.48 | 11399458 16427766 | |
| MESH:D009447 | Neuroblastoma | irinotecan | 3.65 | 8761367 | |
| MESH:D017599 | Neuroectodermal Tumors | irinotecan | 5.36 | 8761367 | |
| MESH:D010049 | Ovarian Diseases | bisphenol A | 5.62 | 11985600 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | bisphenol A | 4.58 | 10548101 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | bisphenol A | 4.63 | 20887781 | |
| MESH:D011471 | Prostatic Neoplasms | Benzo(a)pyrene | 2.63 | 17292933 | |
| MESH:D011471 | Prostatic Neoplasms | bicalutamide | 2.63 | 19011039 19240160 15638997 18487222 17914592 | |
| MESH:D011471 | Prostatic Neoplasms | bisphenol A | 2.63 | 16740699 | |
| MESH:D011629 | Puberty, Precocious | bisphenol A | 5.42 | 10548101 | |
| MESH:D012878 | Skin Neoplasms | Benzo(a)pyrene | 2.52 | 10029692 19755658 | |
| MESH:D013274 | Stomach Neoplasms | Benzo(a)pyrene | 2.63 | 20155912 2093021 | |
| MESH:D013274 | Stomach Neoplasms | irinotecan | 2.63 | 15723263 | |
| MESH:D019966 | Substance-Related Disorders | bisphenol A | 4.61 | 16045194 16684133 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Benzo(a)pyrene | 2.30 | 17053015 | |
| MESH:D014591 | Uterine Diseases | bisphenol A | 5.73 | 14652134 |
| No data |