AutismKB 2.0

Annotation Detail for SLC4A5


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Basic Information Top
Gene Symbol:SLC4A5 ( MGC129662,NBC4 )
Gene Full Name: solute carrier family 4, sodium bicarbonate cotransporter, member 5
Band: 2p13.1
Quick LinksEntrez ID:57835; OMIM: 606757; Uniprot ID:S4A5_HUMAN; ENSEMBL ID: ENSG00000188687; HGNC ID: 18168
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Transmembrane transport of small molecules
No data
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Related Diseases/Disorders Top
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Desease Name
blood pressure, arterial
CARDIOVASCULAR
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SLC4A5 mRNAdecreases expression 20382639
D003010 Clorgyline Clorgyline results in increased expression of SLC4A5 mRNAincreases expression 19691856
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0420889678
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1620426865
MESH:D011471 Prostatic Neoplasms Clorgyline 4.2219691856
Pathway ID Pathway Name
KEGG:04976 Bile secretion
REACT:15518 Transmembrane transport of small molecules
Pharmacogenomics Knowledge Base Top
Drug Bank Top
No data
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Drugbank ID Action Drug Name Description
DB01390 substrate Woodward's Gripe Water Antidiarrheals
No data

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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