AutismKB 2.0

Annotation Detail for ZNF410


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Basic Information Top
Gene Symbol:ZNF410 ( APA-1,APA1 )
Gene Full Name: zinc finger protein 410
Band: 14q24.3
Quick LinksEntrez ID:57862; OMIM: NA; Uniprot ID:ZN410_HUMAN; ENSEMBL ID: ENSG00000119725; HGNC ID: 20144
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ZNF410 mRNAdecreases expression 19150397
D016572 Cyclosporine Cyclosporine results in increased expression of ZNF410 mRNAincreases expression 20106945
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of ZNF410 mRNAdecreases expression 15953391
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.8117505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8914692618
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.1211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.9115885639
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.5420889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.5412371664
MESH:D002779 Cholestasis Cyclosporine 8.8819486331
MESH:D002779 Cholestasis Ethinyl Estradiol 8.8817110522 11677210 16105132 17681005 16919318 15861022 17333356
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.7712538720
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1520426865
MESH:D005234 Fatty Liver Cyclosporine 9.2319224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 9.2315345470
MESH:D005355 Fibrosis Cyclosporine 3.7912639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.968708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.1615720958
MESH:D006973 Hypertension Cyclosporine 2.2310903974
MESH:D007021 Hypospadias Ethinyl Estradiol 4.4616945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7617937319
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.3115604871
MESH:D007674 Kidney Diseases Cyclosporine 2.568314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 3.1212371664
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.6516801185
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.3117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.7019348381 18481113
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.2211578682
MESH:D011230 Precancerous Conditions Cyclosporine 3.6412371664
MESH:D011537 Pruritus Ethinyl Estradiol 4.0516919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.3416882103
MESH:D013088 Spermatocele Ethinyl Estradiol 4.8116709447
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.1511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5715669648
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8814692618
MESH:D014605 Uveitis Cyclosporine 4.851336536
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 4.0215869587 14671159
MESH:D014985 Xerophthalmia Cyclosporine 5.3117120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018