AutismKB 2.0

Annotation Detail for CADM3


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Basic Information Top
Gene Symbol:CADM3 ( BIgR,FLJ10698,IGSF4B,NECL1,Necl-1,TSLL1,synCAM3 )
Gene Full Name: cell adhesion molecule 3
Band: 1q23.2
Quick LinksEntrez ID:57863; OMIM: 609743; Uniprot ID:CADM3_HUMAN; ENSEMBL ID: ENSG00000162706; HGNC ID: 17601
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04514Cell adhesion molecules (CAMs)
Pathway IDPathway Name
Cell junction organization
No data
No data
Pathway IDPathway Name
500121Nectin/Necl trans heterodimerization
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of CADM3 mRNAaffects expression 17484886
C017947 sodium arsenite sodium arsenite affects the expression of CADM3 mRNAaffects expression 19590694
C025643 vinclozolin vinclozolin affects the expression of CADM3 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 5.5715276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 5.7717306315 16712894
MESH:D001008 Anxiety Disorders vinclozolin 4.0019015723
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.4316192424 18705752 10355542 15700767 16097048 15673190 16050911 16227642 3786805 15721981 16011737 16124888
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 3.2218788625
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 3.2217306315 16507464 15276417
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 2.4718572023
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 3.2819524636 20056578
MESH:D003456 Cryptorchidism vinclozolin 4.9314966744
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 2.136623471 10915739 15998439 4309450 3732212 17522070 19336974 16227642 7120509 19085960 16177239 15968718 11566570 9327722 7440962 10092053 3786805 6884620 15027814 2869522 7179309 21278145
MESH:D005234 Fatty Liver Carbon Tetrachloride 3.6517595544 12795759 16045604 19224547 16239168 61145 15959796 12631006
MESH:D005355 Fibrosis Carbon Tetrachloride 4.1018705752
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.6816973722
MESH:D005832 Genital Diseases, Male vinclozolin 6.1716417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 5.4216452187
MESH:D006505 Hepatitis Carbon Tetrachloride 4.1819900420 19110552
MESH:D006689 Hodgkin Disease sodium arsenite 3.5612676792
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 5.2716899240
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.7415338365
MESH:D007248 Infertility, Male sodium arsenite 7.7915346721 12646999
MESH:D007248 Infertility, Male vinclozolin 7.7916467254
MESH:D007674 Kidney Diseases sodium arsenite 3.0220008137
MESH:D007984 Leydig Cell Tumor vinclozolin 5.4716417039
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 3.0216943688 16221502 11408273 16239168 11903743 17174718 21278145 17334410 17157831
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 1.7517698563 18429990 17565644 18412020 18277467 18418968 15931870 15818738 17922224 12666154 16638106 15673190 18472094 18205269 16116963 13678700 18006644 17805973 14748882 16015684 18317297 17557913 17481882 16027843 16011737 18210741 16136751 12632514 12649538 14620537 18472332 10355542 17976157 14512876 17869086 17714472 15925388 18251166 18263696 18156304 12389079 16248980 15959796 17640975 15052691 12546737 12609069 15338365 17766677 12898905 18395095 12445421 11481614 18054572 15123356 18395914 12741479 12445418 18420326 15876570 12586293 18279442 16097048 14716496 14724832 17823541 12958196 12667390 15996030 15370692 15650968 17761835 18705752 15730626 15057751 17708605 15893842 18376398 17944888 17721639 14716833 17525996 16033810 12632512 17900296 16192424 17631135 18481824 18166357 15362042 18339082 18187930 20821823
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.1615720792 15830285 16246199 17285989 16964402
MESH:D017093 Liver Failure Carbon Tetrachloride 4.8215123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 4.1416899240 14706259
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 5.0819294768
MESH:D008113 Liver Neoplasms sodium arsenite 5.0815276417 16712894
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 2.8612014681 15583823
MESH:D008171 Lung Diseases sodium arsenite 3.4519095001
MESH:D008175 Lung Neoplasms sodium arsenite 1.9016712894 17077188 19931552 17306315 15276417
MESH:D008545 Melanoma sodium arsenite 2.0716487513 19082730
MESH:D009369 Neoplasms sodium arsenite 2.6811559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 4.3220056578
MESH:D009436 Neural Tube Defects sodium arsenite 3.4112854658
MESH:D010051 Ovarian Neoplasms sodium arsenite 2.5415276417 17306315
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.6418220299 18042343 19015723
MESH:D011469 Prostatic Diseases vinclozolin 5.6818220299
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.2316039940
MESH:D011472 Prostatitis vinclozolin 5.6818629315
MESH:D012878 Skin Neoplasms sodium arsenite 2.8718572023 19524636
MESH:D016135 Spinal Dysraphism sodium arsenite 4.1412854658
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 2.6417306315 11723127 16712894 16452187
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 4.2111813266
MESH:D014652 Vascular Diseases sodium arsenite 5.1717056641
Pathway ID Pathway Name
KEGG:04514 Cell adhesion molecules (CAMs)
REACT:20676 Cell junction organization
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA162380906
    • No data
    Releated disease ID Related disease Name
    PA443250Acquired Immunodeficiency Syndrome
    No data
    Drug Bank Top

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    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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