AutismKB 2.0

Annotation Detail for PTPRJ


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PTPRJ ( CD148,DEP1,HPTPeta,R-PTP-ETA,SCC1 )
Gene Full Name: protein tyrosine phosphatase, receptor type, J
Band: 11p11.2
Quick LinksEntrez ID:5795; OMIM: 600925; Uniprot ID:PTPRJ_HUMAN; ENSEMBL ID: ENSG00000149177; HGNC ID: 9673
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04520Adherens junction
No data
Pathway IDPathway Name
200032Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
200127PDGFR-beta signaling pathway
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1860Brain tumor
1944Breast cancer
2129Thyroid cancer
2136Hypothyroidism
2207Deafness
Desease Name
CANCER
thyroid cancer
No data
Desease Name
Colon cancer, somatic
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of PTPRJ mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of PTPRJ mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PTPRJ mRNAaffects expression 16483693
C526219 apple polyphenol extract apple polyphenol extract results in increased expression of PTPRJ mRNAincreases expression 18351577
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of PTPRJ mRNAdecreases expression 20064835
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of PTPRJ mRNAincreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of PTPRJ mRNAdecreases expression 19150397
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of PTPRJ mRNAaffects expression 17484886
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of PTPRJ mRNAaffects cotreatment|affects expression 17602206
D016572 Cyclosporine Cyclosporine results in increased expression of PTPRJ mRNAincreases expression 20106945
C007262 deoxynivalenol deoxynivalenol results in increased expression of PTPRJ mRNAincreases expression 15371230
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of PTPRJ mRNAaffects cotreatment|affects expression 17602206
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PTPRJ mRNAaffects cotreatment|increases expression 17942748
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of PTPRJ mRNAaffects cotreatment|increases expression 17183730
D010936 Plant Extracts Plant Extracts results in increased expression of PTPRJ mRNAincreases expression 18351577
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PTPRJ mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of PTPRJ mRNAdecreases expression 19933214
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of PTPRJ mRNAaffects cotreatment|increases expression 17183730
C025643 vinclozolin vinclozolin affects the expression of PTPRJ mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.2814514962 11752688 15322242
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 8.288875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.9119490988
MESH:D000138 Acidosis Ammonium Chloride 3.5518287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9417505938
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.1620127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.1614692618
MESH:D000236 Adenoma Benzo(a)pyrene 6.596695378
MESH:D000236 Adenoma Diethylnitrosamine 6.5910737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 10.0316434500 17620307 17162532 19052882 18056438 19061943
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.0316835633
MESH:D000544 Alzheimer Disease Plant Extracts 3.0116962711
MESH:D000550 Amblyopia Valproic Acid 5.2317688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9311748828
MESH:D000799 Angioedema Acetaminophen 3.8410982225
MESH:D001008 Anxiety Disorders Valproic Acid 8.8017497229
MESH:D001008 Anxiety Disorders vinclozolin 8.8019015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.0619183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.4815885639
MESH:D001169 Arthritis, Experimental Plant Extracts 7.4814686799
MESH:D001321 Autistic Disorder Acetaminophen 1.8518445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8518985861 18396377 15238991 18940202 18558336 17157402 20603192 16609825 17507914 18177632 18316065 19232924 19460635 18775368 17688650
MESH:D001714 Bipolar Disorder Valproic Acid 3.0620046352 17594078
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.0212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.9815746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.988888407
MESH:D002545 Brain Ischemia Plant Extracts 4.7216041641
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.8020146248 17474063
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.8017474063
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.8020435547
MESH:D002057 Burns, Chemical Plant Extracts 5.349625245
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.7716011737 18705752 16097048 15673190 16050911 15700767 16124888 15721981 10355542 16227642 3786805 16192424
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7816835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 8.8516705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 8.853084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 8.8518788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 8.8516540662 17162532 19394651 18494052 19335982 18393292 19701751 17055752 3581430 20514400 20007298 16328049 16779866 16935385 21159647 19052882 16698587 19208518 16288022 16569478 18971187 16502159 17428255 16878318 19822196 20214788 11831363 19919837 18506893 18978308 18056438 19107877 16830150 18788625 10737359 18210153 20935162 10672840 3084413 17761372 18665156 20101231 18785209 20512989 19171122 19383236 20432363 20727157 16807293 20524982 19418558 18691550 17978847 19519916 17173139 16681979 17138121 19539802 20084675
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 8.8518834353
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.0420419170
MESH:D006332 Cardiomegaly Plant Extracts 6.9417645561
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.9418850075 18670907 16120746
MESH:D002386 Cataract Acetaminophen 2.5710977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 11.0620889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 11.0612371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 11.0621159647 2727394 17174075 7505956
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.7020734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.2619052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.2616835633
MESH:D002779 Cholestasis Cyclosporine 7.7219486331
MESH:D002779 Cholestasis Ethinyl Estradiol 7.7217681005 11677210 16105132 16919318 15861022 17110522 17333356
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0915668235 16354765 8697196 12621046 15340226
MESH:D015179 Colorectal Neoplasms marker/mechanism
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0417141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4715322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Valproic Acid 2.478888407 17688650 16575769
MESH:D003456 Cryptorchidism vinclozolin 4.3214966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.0018551238
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.2020387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.2017107852
MESH:D003928 Diabetic Nephropathies Plant Extracts 4.3919706694
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 15.1921346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 15.1919923254 12540782 17522070 11287661 11834606 18713872 16177239 11529661 19164858 16485898 15968718 12153990 19085960 10774834 11421492 11739529 12958197 12705907 17906064 17562736 16109766 16393943 2444490 10663392 19739265 12392966 11461765 14550746 19420014 11743745 14986274 18071297 16781746 19370779 16227642 10915739 19416960 14725611 15619225 16081117 12594235
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 15.1915998439 17522070 3786805 15027814 16177239 15968718 19336974 21278145 19085960 4309450 7120509 10915739 11566570 9327722 16227642 2869522 7440962 10092053 6623471 6884620 3732212 7179309
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 15.1919107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 15.1920420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 15.1919641884 1733752
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1019426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7411462148
MESH:D004421 Dystonia Valproic Acid 4.031851702
MESH:D004487 Edema Plant Extracts 6.9712787963
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.9711000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9015322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.1712538720
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.009294722 10568697
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 5.6815268973
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.1417275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 3.923922381 16628512
MESH:D004827 Epilepsy Plant Extracts 6.9419439326 19700373
MESH:D004827 Epilepsy Valproic Acid 6.9418234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.577562514 6426943 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.287750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.063659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.1216302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.3320426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.3316530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0011564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 30.5317595544 12631006 16045604 12795759 16239168 19224547 61145 15959796
MESH:D005234 Fatty Liver Cyclosporine 30.5319224547
MESH:D005234 Fatty Liver Diethylnitrosamine 30.5321071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 30.5315345470
MESH:D005234 Fatty Liver Plant Extracts 30.5315975614
MESH:D005234 Fatty Liver Valproic Acid 30.5314986274 19224547
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4411858732
MESH:D005315 Fetal Diseases Valproic Acid 4.8916575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.118888407 18558336
MESH:D005355 Fibrosis Carbon Tetrachloride 14.6418705752
MESH:D005355 Fibrosis Cyclosporine 14.6412639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.6420067830
MESH:D005756 Gastritis Acetaminophen 3.6816983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.9316973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.3016417039
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.218708960
MESH:D005922 Glomerulonephritis, IGA deoxynivalenol 4.9916524712 15173396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5910696789
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.4120471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.4110048152 11294989
MESH:D006333 Heart Failure Plant Extracts 3.8518097624
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.4115720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3211000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.5819900420 19110552
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.8816120746 15340226 12621046
MESH:D006561 Herpes Simplex Plant Extracts 4.6210715843
MESH:D015658 HIV Infections Plant Extracts 3.6712878215
MESH:D019584 Hot Flashes Plant Extracts 4.7517454163 16566672 14716179
MESH:D006849 Hydrocephalus Valproic Acid 4.8617688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.058697196 18606429 16354765 16959395 15340226
MESH:D006930 Hyperalgesia Acetaminophen 2.6816870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.5216899240
MESH:D020138 Hyperhomocysteinemia Plant Extracts 4.4416484555
MESH:D006949 Hyperlipidemias Plant Extracts 4.4515268973 15975614
MESH:D006973 Hypertension Cyclosporine 4.9210903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.9218850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.0715338365
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.6116612254
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8016569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4412013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.6117937319
MESH:D007248 Infertility, Male vinclozolin 6.6116467254
MESH:D007249 Inflammation Diethylnitrosamine 8.3318785209
MESH:D007249 Inflammation Plant Extracts 8.3312787963 16366677 15997105 19332304
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.3312200463 12878042
MESH:D007414 Intestinal Neoplasms Plant Extracts 4.6012584176 12351151 12628509
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3216580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.4415604871
MESH:D007674 Kidney Diseases Acetaminophen 5.7512587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 5.758314463 10903974 18776723
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 7.2116705839
MESH:D007680 Kidney Neoplasms Cyclosporine 7.2112371664
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1517596541 16294345
MESH:D007984 Leydig Cell Tumor vinclozolin 4.7216417039
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 11.0711903743 16239168 16943688 16221502 11408273 17157831 21278145 17174718 17334410
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 11.0718522880 20032147 18407596 19638242 18665156
MESH:D008103 Liver Cirrhosis Plant Extracts 11.0717157831
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 3.5514716496 14748882 15818738 18277467 17714472 17565644 18412020 16136751 17557913 16638106 18251166 17900296 12445418 15893842 17805973 20821823 14620537 15650968 15123356 14724832 18205269 18156304 17721639 18472094 18054572 17922224 16248980 16011737 17708605 15931870 18395914 16097048 12546737 16033810 18376398 17976157 17823541 17766677 18210741 17869086 15673190 17525996 18006644 14716833 15730626 12667390 15370692 12741479 17698563 18187930 15925388 15052691 17761835 18418968 12632514 18166357 18279442 18481824 18429990 15959796 12898905 12649538 12389079 17631135 18339082 18263696 15338365 12632512 14512876 16192424 12666154 11481614 10355542 18420326 16027843 15876570 15362042 12586293 16015684 12445421 17481882 17640975 12609069 18472332 18317297 17944888 13678700 15996030 12958196 15057751 18705752 16116963 18395095
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 3.5515479170
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.5512878042
MESH:D008107 Liver Diseases Acetaminophen 9.3716610002 19014921 12587719 19784758 11587558 16611625 19460945 12969438
MESH:D008107 Liver Diseases Carbon Tetrachloride 9.3715720792 17285989 15830285 16964402 16246199
MESH:D008107 Liver Diseases Diethylnitrosamine 9.3717034775
MESH:D008107 Liver Diseases Plant Extracts 9.3717034775
MESH:D017093 Liver Failure Carbon Tetrachloride 4.1515123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.3516871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.3516899240 14706259
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 17.9020195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 17.9019294768
MESH:D008113 Liver Neoplasms Clofibric Acid 17.9017602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 17.9019850985 19426721 20434301 19090486 20452335 12112319 21167192 9163691 18644402 18978307 20583210 20118626 15175105 19833225 19254457 16942905 15885732 12771043 18754104 21278145 19294768 19996281 20101389 21071580 18648771 19256749 19812893 19255062 18977376 21047994 19551842 19638242 19642983 19427195 20137499 19499222 2862719 20405173 19690152 20501860 10737359 20492335 19073162 2422723
MESH:D008113 Liver Neoplasms Plant Extracts 17.9019168119
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.9016984957
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 9.7212014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 9.7217942915 21159647 18282651 18308698 19126423 16267830 17174075 19539802 18093689 18544905 19519916 18775883 18253720 18079962 3124819 17854601 18164116 16842330 2563599 19009564 19004024 9362446
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.7212151625
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.2617228818
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 4.8418816296 20064080 18520028 20135361 20464547 20869020 17053015 6695378 18569708
MESH:D008175 Lung Neoplasms Diethylnitrosamine 4.8420970405 6695378 20512841 21163286
MESH:D008175 Lung Neoplasms Plant Extracts 4.8420869020
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.8419555203 11884234
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5519513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7916801185
MESH:D008881 Migraine Disorders Valproic Acid 3.1718765137 18803445
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.1716381670
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.018888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.1417596541
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0012213967
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.8518551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.563581430 9029167
MESH:D009369 Neoplasms Benzo(a)pyrene 2.1611141357
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.4417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2719348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.2014600291
MESH:D009436 Neural Tube Defects Valproic Acid 3.1116359493 8888407
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 5.1717168769
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.1218514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 8.1220387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.1220387270
MESH:D009765 Obesity Plant Extracts 3.1419056576 20132043
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.4116049721 12819281
MESH:D010146 Pain Acetaminophen 2.3716870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.4116540662
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6711578682
MESH:D010212 Papilloma Plant Extracts 4.4815173996 16517061
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2512520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5418163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.8812371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.882563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 16.2011118676 11896295 11222880 11399792
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 16.2020603192
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 16.2019015723 18042343 18220299
MESH:D011469 Prostatic Diseases vinclozolin 4.9318220299
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.4817292933
MESH:D011471 Prostatic Neoplasms Plant Extracts 3.4814666653 17804756
MESH:D011472 Prostatitis vinclozolin 4.9318629315
MESH:D011537 Pruritus Ethinyl Estradiol 3.3016919318 15861022
MESH:D019310 Pseudolymphoma Valproic Acid 4.5411422049 12752131
MESH:D011565 Psoriasis Cyclosporine 2.2216882103
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8218990726
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.1619155313
MESH:D012559 Schizophrenia Valproic Acid 2.0715737665 19110320
MESH:D012640 Seizures 2,4-dinitrotoluene 5.8918551238
MESH:D012640 Seizures Valproic Acid 5.8916876388 1511512 15475178 14763951 17978042 3137016 11738929 11044598
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 9.4510029692 19755658
MESH:D012878 Skin Neoplasms Plant Extracts 9.4516517061 15173996
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.4516192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.9416709447
MESH:D016135 Spinal Dysraphism Valproic Acid 3.7619490988
MESH:D013226 Status Epilepticus Valproic Acid 4.5412833885
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.332093021 20155912
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.3318456281
MESH:D013276 Stomach Ulcer Plant Extracts 3.8818237397 18193104 17135157 12787963 15255614
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 5.4817997062
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1315669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9012697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 2.977505956
MESH:D014178 Translocation, Genetic Valproic Acid 5.2317262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.513119515
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 4.9416049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 4.9417053015
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.638888407
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.3110091137
MESH:D014581 Urticaria Acetaminophen 2.9610982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2814692618
MESH:D014605 Uveitis Cyclosporine 3.981336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5912125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5214671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 4.7318097624
MESH:D020257 Ventricular Remodeling Plant Extracts 5.3118097624
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2515886252
MESH:D014947 Wounds and Injuries Plant Extracts 4.2319894650 20213670
MESH:D014985 Xerophthalmia Cyclosporine 4.4417120751
Pathway ID Pathway Name
KEGG:04520 Adherens junction
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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