AutismKB 2.0

Annotation Detail for PZP


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Basic Information Top
Gene Symbol:PZP ( CPAMD6,MGC133093 )
Gene Full Name: pregnancy-zone protein
Band: 12p13.31
Quick LinksEntrez ID:5858; OMIM: 176420; Uniprot ID:; ENSEMBL ID: ENSG00000126838; HGNC ID: 9750
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of PZP mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of PZP mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of PZP mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen affects the expression of PZP proteinaffects expression 16099942
D000638 Amiodarone Amiodarone affects the expression of PZP mRNAaffects expression 19483382
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PZP mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in decreased expression of PZP mRNAdecreases expression 20458559
D001553 Benzbromarone Benzbromarone affects the expression of PZP mRNAaffects expression 19483382
C032036 bromobenzene bromobenzene results in decreased expression of PZP mRNAdecreases expression 12628495
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PZP mRNAaffects cotreatment|decreases expression 20360939
D002330 Carmustine Carmustine results in decreased expression of PZP mRNAdecreases expression 15980968
D002994 Clofibrate Clofibrate affects the expression of PZP mRNAaffects expression 19483382
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PZP mRNAaffects cotreatment|decreases expression 20360939
D004958 Estradiol Estradiol results in decreased expression of PZP mRNAdecreases expression 16705744
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PZP mRNAaffects cotreatment|increases expression 17942748
D005001 Ethionine Ethionine affects the expression of PZP mRNAaffects expression 19483382
D005419 Flavonoids Flavonoids results in increased expression of PZP mRNAincreases expression 18035473
C056933 fumonisin B1 fumonisin B1 results in decreased expression of PZP mRNAdecreases expression 16221962
D019833 Genistein Genistein results in increased expression of PZP mRNAincreases expression 16705744
D009853 Omeprazole Omeprazole affects the expression of PZP mRNAaffects expression 19483382
C006253 pirinixic acid pirinixic acid affects the expression of PZP mRNAaffects expression 19483382
D011441 Propylthiouracil Propylthiouracil affects the expression of PZP mRNAaffects expression 19483382
C017947 sodium arsenite sodium arsenite affects the expression of PZP mRNAaffects expression 17450228
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PZP mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of PZP mRNAdecreases expression 18178546
D013853 Thioacetamide Thioacetamide affects the expression of PZP mRNAaffects expression 19483382
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.6815322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.3918287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7717505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.9618653653
MESH:D000230 Adenocarcinoma arsenic trioxide 9.8111798837 19825857
MESH:D000230 Adenocarcinoma Estradiol 9.8111473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 9.8114692618
MESH:D000230 Adenocarcinoma Genistein 9.8111473722
MESH:D000236 Adenoma Diethylnitrosamine 2.7510737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 16.2817162532 19061943 18056438 19052882 17620307 16434500
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.2816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.2816835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.5315276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.7317306315 16712894
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8011748828
MESH:D000799 Angioedema Acetaminophen 3.6710982225
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.6518218290 20041841 18057881
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2911256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5615885639
MESH:D001281 Atrial Fibrillation Amiodarone 3.7818651412 19698954
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001778 Blood Coagulation Disorders Amiodarone 63.0019483382
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 63.0016206674
MESH:D001778 Blood Coagulation Disorders Benzbromarone 63.0019483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 63.0019483382
MESH:D001778 Blood Coagulation Disorders Ethionine 63.0019483382
MESH:D001778 Blood Coagulation Disorders Omeprazole 63.0019483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 63.0019483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 63.0019483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 63.0012125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 63.0019483382
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6515746008
MESH:D001932 Brain Neoplasms Carmustine 4.2416187019
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.9117474063
MESH:D001943 Breast Neoplasms Estradiol 1.9112948864 16675129 14630087 17018787 17289903 19861407 17261762 18497071
MESH:D001943 Breast Neoplasms Genistein 1.9116873071 16541309 17200150
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9120435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1711589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.2916111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6616835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 22.4216705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 22.4216705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 22.423084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 22.4215553829 16217749 15073043 11135700 14691202
MESH:D006528 Carcinoma, Hepatocellular Benzbromarone 22.421701930
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 22.4219208518 10737359 10672840 17428255 19539802 20084675 16935385 18210153 16878318 19418558 16698587 20935162 16830150 19822196 18494052 17761372 18978308 19335982 20214788 20432363 19383236 19394651 18788625 20512989 17978847 3581430 19701751 11831363 20727157 21159647 19107877 16807293 17162532 19519916 20101231 16779866 17055752 18393292 18506893 18971187 19919837 18056438 16569478 18691550 20514400 16681979 16502159 18785209 16328049 19052882 16540662 20007298 19171122 3084413 17138121 18665156 16288022 20524982 17173139
MESH:D006528 Carcinoma, Hepatocellular Estradiol 22.4216924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 22.4216924424
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 22.4216507464 17306315 15276417
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 22.4217997003
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7019014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9712490120
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 2.3318572023
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2716120746 18850075 18670907
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.8315710769 19225199
MESH:D002318 Cardiovascular Diseases Genistein 3.1916332659
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.9118974383
MESH:D002386 Cataract Acetaminophen 2.4810977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 19.866135515
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 19.861399818
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 19.8621159647 2727394 7505956 17174075
MESH:D002471 Cell Transformation, Neoplastic Estradiol 19.8618566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 19.8620056578 19524636
MESH:D002637 Chest Pain Omeprazole 4.9315447763
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 15.2819052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 15.2816835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 15.2818291259
MESH:D002779 Cholestasis Ethinyl Estradiol 7.3217681005 15861022 17333356 16919318 16105132 11677210 17110522
MESH:D002779 Cholestasis pirinixic acid 7.3219176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0316354765 8697196 15668235 12621046 15340226
MESH:D003110 Colonic Neoplasms Genistein 2.2617182828
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9114669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 4.0212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.4210525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4210048152 20055451 15322242
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.3318551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.3318551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9315213294
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3518249437
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.8520387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 6.8516647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.8517107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.2719279558
MESH:D056486 Drug-Induced Liver Injury marker/mechanism 16099942
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 24.9618551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 24.9621346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 24.9619923254 11421492 12153990 16109766 12705907 17522070 19164858 16485898 11529661 19416960 12594235 16227642 2444490 18071297 12540782 11461765 11739529 10774834 10663392 11834606 11743745 12392966 10915739 16177239 11287661 17562736 17906064 14986274 14550746 16081117 15619225 19370779 18713872 16781746 19420014 14725611 12958197 19739265 19085960 15968718 16393943
MESH:D056486 Drug-Induced Liver Injury Amiodarone 24.9618218290 15265979
MESH:D056486 Drug-Induced Liver Injury bromobenzene 24.9610092053 12628495
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 24.9619107877
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 24.9616221962
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 24.9620420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 24.9612963478
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9319426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6311462148
MESH:D004381 Duodenal Ulcer Omeprazole 4.1617151854 15991576 21218061 16613094
MESH:D050171 Dyslipidemias Clofibrate 3.9416707586
MESH:D004487 Edema pirinixic acid 6.0312083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.0311000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7315322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.0212538720
MESH:D004714 Endometrial Hyperplasia Genistein 4.4216402032
MESH:D016889 Endometrial Neoplasms Estradiol 7.1411473722 19148513 18566989
MESH:D016889 Endometrial Neoplasms Genistein 7.1411473722
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.8710568697 9294722
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9416302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.2712903497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8911564622
MESH:D005218 Fat Necrosis Thioacetamide 5.5516456712
MESH:D005234 Fatty Liver Amiodarone 28.6914986274
MESH:D005234 Fatty Liver arsenic trioxide 28.6915073043
MESH:D005234 Fatty Liver Clofibrate 28.6919224547
MESH:D005234 Fatty Liver Diethylnitrosamine 28.6921071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 28.6915345470
MESH:D005234 Fatty Liver pirinixic acid 28.6919236843 20131406
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2911858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 2.7820067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1016904648
MESH:D005756 Gastritis Acetaminophen 3.5016983495
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.5116452187
MESH:D005909 Glioblastoma Carmustine 7.1816187019
MESH:D005909 Glioblastoma Genistein 7.1816598420
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4210696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2411294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.4320558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1811000095
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.4218665440 15929193 17276928
MESH:D006505 Hepatitis Thioacetamide 4.0516456712
MESH:D006529 Hepatomegaly Amiodarone 19.3115265979
MESH:D006529 Hepatomegaly fumonisin B1 19.3116221962
MESH:D006529 Hepatomegaly pirinixic acid 19.3118467677 16221962 19772884 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 19.3115340226 12621046 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.8615709030
MESH:D006689 Hodgkin Disease sodium arsenite 3.0112676792
MESH:D019584 Hot Flashes Estradiol 3.5817088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.878697196 16354765 16959395 18606429 15340226
MESH:D006930 Hyperalgesia Acetaminophen 2.5716870215
MESH:D006937 Hypercholesterolemia Amiodarone 3.728137927 9751232
MESH:D006943 Hyperglycemia pirinixic acid 3.0320558911
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8418670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6416569931 16945680
MESH:D007037 Hypothyroidism Amiodarone 11.0417991464 18020914
MESH:D007037 Hypothyroidism Propylthiouracil 11.0418031379 8137927
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3012013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.2617937319
MESH:D007248 Infertility, Male sodium arsenite 6.2612646999 15346721
MESH:D007249 Inflammation Diethylnitrosamine 7.7918785209
MESH:D007249 Inflammation Flavonoids 7.7917296493
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.7912200463 12878042
MESH:D007333 Insulin Resistance Estradiol 6.8316627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 6.8316306350
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.4410783313
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1816580747
MESH:D007674 Kidney Diseases Acetaminophen 13.6712587719 15629191
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 13.6715369732
MESH:D007674 Kidney Diseases Estradiol 13.6715618244
MESH:D007674 Kidney Diseases sodium arsenite 13.6720008137
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 11.5916705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 11.5916705839
MESH:D007680 Kidney Neoplasms Estradiol 11.5915610895
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 3.9619248655
MESH:D007938 Leukemia arsenic trioxide 6.1515070760
MESH:D007938 Leukemia Genistein 6.1518980019 17468513
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.6417077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.1316972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3014633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.6019077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1117050201 16467208 16968895 19850784 20471514
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.5711468182 17217047 15213294 11161223 16891316 15622746 15748426 16966277 9834237 17869043 19035177 19225113 12712474 16823087 19642359 12018890 16330433 17649720 16331271 12679006 15336539 17107899 19075265 16112521 17712046
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 7.5716766008
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.1916882451
MESH:D008064 Lipidoses Amiodarone 3.3917567588 15342952
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.7318407596 19638242 20032147 18665156 18522880
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.5014716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 6.5017823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.5015474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.5012878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 6.5017050028 15288472 11172339 15474484 18395095 18458672 18032466 17355460 11481614 16343077 15078482 15465738 14739098 18295389 18263696 15095483 15288473 15158331 12891558 18380797 18615449 16248980 18416461 15362042 12085344 12175628 15316131 17629604 10677585 11682029 12557150 18031379 15334695 17292413 17127702 16489207 18606216 15716488 16511523 12531686 12679928 16097051 16126171 16098781 15075984
MESH:D008107 Liver Diseases Acetaminophen 6.2912587719 12969438 16611625 19460945 11587558 19014921 19784758 16610002
MESH:D008107 Liver Diseases Diethylnitrosamine 6.2917034775
MESH:D008107 Liver Diseases Thioacetamide 6.2916337175 15158337 18374380
MESH:D017114 Liver Failure, Acute Acetaminophen 9.1316871587 17185352
MESH:D017114 Liver Failure, Acute Thioacetamide 9.1315313186 15633222 12479984 17276928
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 17.137678174
MESH:D008113 Liver Neoplasms arsenic trioxide 17.1314682389
MESH:D008113 Liver Neoplasms Diethylnitrosamine 17.1318644402 15885732 19090486 19996281 2862719 21278145 19833225 19255062 21047994 12771043 19551842 18977376 20492335 15175105 10737359 18648771 19073162 19690152 9163691 19254457 20452335 19499222 19812893 19426721 19256749 20434301 19427195 12112319 20501860 20583210 20405173 20101389 18978307 21167192 20118626 19294768 2422723 20137499 16942905 19638242 21071580 18754104 19642983 19850985
MESH:D008113 Liver Neoplasms pirinixic acid 17.1315890375 20007298 16377806
MESH:D008113 Liver Neoplasms sodium arsenite 17.1316712894 15276417
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.1316984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 13.232876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 13.2320377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 13.2319126423 16842330 19519916 16267830 18093689 21159647 9362446 19009564 18775883 18282651 2563599 18308698 19004024 19539802 18079962 18253720 18164116 17174075 17942915 17854601 3124819 18544905
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.2312151625
MESH:D008133 Long QT Syndrome Amiodarone 7.7611989578 15350150 17391786
MESH:D008133 Long QT Syndrome arsenic trioxide 7.7615213294
MESH:D008171 Lung Diseases Amiodarone 7.1412587719
MESH:D008171 Lung Diseases sodium arsenite 7.1419095001
MESH:D017563 Lung Diseases, Interstitial Amiodarone 4.3118516814
MESH:D008175 Lung Neoplasms arsenic trioxide 4.6711798837 19825857
MESH:D008175 Lung Neoplasms Diethylnitrosamine 4.6720970405 20512841 21163286 6695378
MESH:D008175 Lung Neoplasms sodium arsenite 4.6719931552 17306315 16712894 15276417 17077188
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.6711884234 19555203
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 5.7211807958 11408345 17203775 16891317
MESH:D008325 Mammary Neoplasms, Experimental Genistein 5.7214578162 12929590
MESH:D020149 Manganese Poisoning Estradiol 4.3119453300
MESH:D008545 Melanoma Carmustine 3.5812393984
MESH:D008545 Melanoma sodium arsenite 3.5816487513 19082730
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4019513568
MESH:D009101 Multiple Myeloma arsenic trioxide 2.9814977855 15949261 19417148 19549372 11468182
MESH:D009135 Muscular Diseases pirinixic acid 3.3416239165
MESH:D009181 Mycoses Amiodarone 4.7317974566 12754197
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5018349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.0516882451 16105982
MESH:D009203 Myocardial Infarction Genistein 5.4417141266
MESH:D009203 Myocardial Infarction pirinixic acid 5.4419151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 13.4116810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 13.4117141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 13.4116411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 9.7718551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 9.777678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.7916624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.503581430 9029167
MESH:D009369 Neoplasms pirinixic acid 4.6617405874
MESH:D009369 Neoplasms sodium arsenite 4.6611559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.5020056578
MESH:D009389 Neovascularization, Pathologic Estradiol 3.5617289903
MESH:D009421 Nervous System Malformations Estradiol 15.4011399458 16427766
MESH:D009421 Nervous System Malformations Genistein 15.4016427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 15.4014600291
MESH:D009436 Neural Tube Defects arsenic trioxide 6.9710525206
MESH:D009436 Neural Tube Defects sodium arsenite 6.9712854658
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.7118514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.7120387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9420387270
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 4.779802331
MESH:D009765 Obesity pirinixic acid 1.7720558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 8.3816049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.3816049721
MESH:D010024 Osteoporosis Genistein 3.1519401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.9216169203
MESH:D010051 Ovarian Neoplasms arsenic trioxide 10.8516624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Estradiol 10.8519401270
MESH:D010051 Ovarian Neoplasms Genistein 10.8519005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 10.8515276417 17306315
MESH:D010146 Pain Acetaminophen 2.2516870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 5.0715580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.0716540662
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5311578682
MESH:D010235 Paraganglioma arsenic trioxide 4.0019927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0812520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3918163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.412563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.0211222880 11118676 11399792 11896295
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.7320887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.1119131511
MESH:D011471 Prostatic Neoplasms Estradiol 2.1116740699
MESH:D011471 Prostatic Neoplasms Genistein 2.1115256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.1116039940
MESH:D011537 Pruritus Ethinyl Estradiol 3.1415861022 16919318
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.7911597910 12490602 12832656
MESH:D015427 Reperfusion Injury pirinixic acid 2.3019058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6718990726
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.7916646077
MESH:D012640 Seizures 2,4-dinitrotoluene 5.4818551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.4818551238
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.9118724381
MESH:D012878 Skin Neoplasms sodium arsenite 5.3319524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.3316192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.7716709447
MESH:D016135 Spinal Dysraphism sodium arsenite 3.6612854658
MESH:D013272 Stomach Diseases Omeprazole 4.4418545984
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.4017007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.4018456281
MESH:D013276 Stomach Ulcer Amiodarone 7.0618087811
MESH:D013276 Stomach Ulcer Omeprazole 7.0617977527 18237397 11906479 15991576 10750652 16755016
MESH:D013610 Tachycardia Amiodarone 4.1211238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.0219225199
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0115669648
MESH:D013959 Thyroid Diseases Amiodarone 11.4819731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 11.4812697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 11.3119014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 11.317505956
MESH:D013964 Thyroid Neoplasms Propylthiouracil 11.3115710170
MESH:D013971 Thyrotoxicosis Amiodarone 4.6919584973 18020914
MESH:D013978 Tibial Fractures Estradiol 4.5119048282
MESH:D016171 Torsades de Pointes Amiodarone 9.6817467628 11989578
MESH:D016171 Torsades de Pointes arsenic trioxide 9.6815213294
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 11.3716049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 11.3716049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 11.3711780464 20435036 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 11.3717306315 11723127 16452187 16712894
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.4110091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.4110091137
MESH:D014581 Urticaria Acetaminophen 2.8210982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.6211813266
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1314692618
MESH:D014652 Vascular Diseases sodium arsenite 4.2517056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4212125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3814671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0815886252
No data
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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