AutismKB 2.0

Annotation Detail for RAD23B


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Basic Information Top
Gene Symbol:RAD23B ( HHR23B,HR23B,P58 )
Gene Full Name: RAD23 homolog B (S. cerevisiae)
Band: 9q31.2
Quick LinksEntrez ID:5887; OMIM: 600062; Uniprot ID:RD23B_HUMAN; ENSEMBL ID: ENSG00000119318; HGNC ID: 9813
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04141Protein processing in endoplasmic reticulum
hsa03420Nucleotide excision repair
Pathway IDPathway Name
DNA Repair
No data
No data
Pathway IDPathway Name
500059DNA Damage Recognition in GG-NER
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1944Breast cancer
2007Liver tumor
2022Liver cancer
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C063002 2,3-dimethoxy-1,4-naphthoquinone 2,3-dimethoxy-1,4-naphthoquinone results in decreased expression of RAD23B mRNAdecreases expression 19031421
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of RAD23B mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of RAD23B mRNAincreases expression 18648102
D013196 Dihydrotestosterone Dihydrotestosterone results in decreased expression of RAD23B mRNAdecreases expression 17023530
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RAD23B mRNAdecreases expression 19150397
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of RAD23B mRNAincreases expression 20018196
D016572 Cyclosporine Cyclosporine results in increased expression of RAD23B mRNAincreases expression 20106945
C014347 decitabine [decitabine co-treated with Depsipeptides] results in decreased expression of RAD23B mRNAaffects cotreatment|decreases expression 17064661
D047630 Depsipeptides [decitabine co-treated with Depsipeptides] results in decreased expression of RAD23B mRNAaffects cotreatment|decreases expression 17064661
D004128 Dimethylnitrosamine Dimethylnitrosamine results in decreased expression of RAD23B mRNAdecreases expression 19031421
D005472 Fluorouracil Fluorouracil results in increased expression of RAD23B mRNAincreases expression 15109396
D005472 Fluorouracil RAD23B affects the susceptibility to Fluorouracilaffects response to substance 15067352
D007213 Indomethacin Indomethacin results in decreased expression of RAD23B mRNAdecreases expression 16984733
C051890 irinotecan irinotecan metabolite results in decreased expression of RAD23B mRNAdecreases expression 15956246
C051890 irinotecan irinotecan results in decreased expression of RAD23B mRNAdecreases expression 15956246
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of RAD23B mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of RAD23B mRNAincreases expression 18301758
C059514 resveratrol resveratrol affects the expression of RAD23B mRNAaffects expression 15748624
C010327 salinomycin salinomycin results in decreased expression of RAD23B mRNAdecreases expression 19682730
D012643 Selenium Selenium results in decreased expression of RAD23B mRNAdecreases expression 19244175
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of RAD23B mRNAincreases expression 20159946
D014810 Vitamin E Vitamin E results in decreased expression of RAD23B mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.8114514962 15322242 11752688
MESH:D058186 Acute Kidney Injury resveratrol 3.8116538975
MESH:D055371 Acute Lung Injury pirinixic acid 3.0818653653
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 7.2416033868
MESH:D000230 Adenocarcinoma Fluorouracil 7.2417638652
MESH:D000230 Adenocarcinoma Indomethacin 7.2416537180
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 15.853712494
MESH:D000236 Adenoma Dimethylnitrosamine 15.8519555203
MESH:D000236 Adenoma Indomethacin 15.8511497255
MESH:D000236 Adenoma resveratrol 15.8515688382
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.7816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.7816835633
MESH:D016301 Alveolar Bone Loss Indomethacin 5.3417225004
MESH:D000544 Alzheimer Disease Indomethacin 4.4517627676 15579461
MESH:D000544 Alzheimer Disease resveratrol 4.4516162502 16183991
MESH:D000740 Anemia Fluorouracil 8.5517963324 16511603 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.5511748828
MESH:D001014 Aortic Aneurysm Indomethacin 4.8110231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.8310388637
MESH:D018771 Arthralgia Indomethacin 5.142160914
MESH:D001169 Arthritis, Experimental resveratrol 3.4717115116
MESH:D001172 Arthritis, Rheumatoid Indomethacin 2.8111248219
MESH:D050197 Atherosclerosis resveratrol 3.2517967414 16873680
MESH:D001477 Bartter Syndrome Indomethacin 4.9410684365
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.991440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.6319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.6312125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7315746008
MESH:D001929 Brain Edema Indomethacin 5.0011481608
MESH:D002545 Brain Ischemia Indomethacin 10.2412524144
MESH:D002545 Brain Ischemia resveratrol 10.2417600658
MESH:D001943 Breast Neoplasms decitabine 2.9519208741 18320071
MESH:D001943 Breast Neoplasms Fluorouracil 2.9516595493 16110121 16557594 18357371 19217205 15136595 18608205
MESH:D001943 Breast Neoplasms Indomethacin 2.9517401462
MESH:D001943 Breast Neoplasms resveratrol 2.9517534123 16393696 17651959
MESH:D001943 Breast Neoplasms salinomycin 2.9519682730
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.9520435547
MESH:D002056 Burns Indomethacin 4.6610459503
MESH:D002100 Cachexia Indomethacin 4.9711239499 15625704 15141370 16537180
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.8916050911
MESH:D002276 Carcinoid Tumor Fluorouracil 4.6416051944
MESH:D002277 Carcinoma Dimethylnitrosamine 13.7919555203
MESH:D002277 Carcinoma Fluorouracil 13.7917121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 13.7916835633
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 8.8216705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 8.827296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 8.8217088986 17971768 18930000 16332177 16799960 17045692
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 8.8216391822
MESH:D006528 Carcinoma, Hepatocellular resveratrol 8.8219321006 16227395
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 11.3111053908
MESH:D018827 Carcinoma, Lewis Lung resveratrol 11.3116675471
MESH:D018276 Carcinoma, Medullary Indomethacin 5.3214736730 18791128 11352223
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 10.697296757
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 10.6918695887
MESH:D002292 Carcinoma, Renal Cell Indomethacin 10.6917341418
MESH:D002294 Carcinoma, Squamous Cell decitabine 14.2419215824
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 14.2416033868
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 14.2417066447 18986760 16757204 16280240
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 14.2415482327 12636206
MESH:D002294 Carcinoma, Squamous Cell resveratrol 14.2416227395
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3418670907 16120746 18850075
MESH:D002318 Cardiovascular Diseases resveratrol 3.4415458977
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 15.756135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 15.757505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 15.7520889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 15.7512371664
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1216835633
MESH:D002764 Cholecystitis Indomethacin 5.1411181007
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 13.199022650 19486331
MESH:D002779 Cholestasis Cyclosporine 13.1919486331
MESH:D002779 Cholestasis pirinixic acid 13.1919176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0815668235 15340226 16354765 8697196 12621046
MESH:D003092 Colitis resveratrol 9.5216474422
MESH:D003092 Colitis Selenium 9.5217936198
MESH:D003110 Colonic Neoplasms decitabine 11.0517616700
MESH:D003110 Colonic Neoplasms Fluorouracil 11.0515001691 17169374 17725105 17018589 16510598 18772588 17016597 17287894 17172411 16340194
MESH:D003110 Colonic Neoplasms Indomethacin 11.0515936596 15637740 15786552 15963497 15625704 11260862
MESH:D003110 Colonic Neoplasms irinotecan 11.0517725105 17287894
MESH:D003110 Colonic Neoplasms resveratrol 11.0516338953
MESH:D015179 Colorectal Neoplasms decitabine 6.4618981723
MESH:D015179 Colorectal Neoplasms Fluorouracil 6.4618288408 20501625 15289873 17695437 17594712 16282729 17255274 17401013 16331619 17454858 16391804 16303861 17094418 18383874 18949393 18802399 17016601 18509181 14970324 16524972 18448328 15148649
MESH:D015179 Colorectal Neoplasms Indomethacin 6.4611197048 12606626 17054584 18059344
MESH:D015179 Colorectal Neoplasms irinotecan 6.4616391804 18509181 18259882 17454858 15273666 16303861 17159606
MESH:D015179 Colorectal Neoplasms resveratrol 6.4616550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0217141729 14669216
MESH:D003327 Coronary Disease resveratrol 3.7216507316
MESH:D018352 Coronavirus Infections Indomethacin 5.6917302372
MESH:D019465 Craniofacial Abnormalities marker/mechanism 11809813
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4720055451 15322242 10048152
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.4719769572
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.9818551238
MESH:D007644 Darier Disease Fluorouracil 4.7616733453
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.772524372 18759878 8970840 11906362 11298694 14531868 8156756 12868966
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4018249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.453621924 2952479
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.7316873680
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6617107852
MESH:D003928 Diabetic Nephropathies resveratrol 3.9216286809
MESH:D003967 Diarrhea Indomethacin 3.757237001 7907874
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 11.8918551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 11.897440962 6482804 18289764 9328219 18692083 9653073 1440618 11289319 16192314 8291058 6679447 9022650 18648102
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 11.898172417
MESH:D056486 Drug-Induced Liver Injury Selenium 11.8915131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.8920420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7311462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 5.1118446180 18043480 12774134 16133044 16326151 17190690
MESH:D004381 Duodenal Ulcer Indomethacin 4.0917329845 16699067 17351913 17202747 11535926 11595431 17151854 10671773 17045617 11595415 11991626
MESH:C538011 Eales disease Vitamin E 4.689068938
MESH:D004487 Edema Indomethacin 16.1319703484 16100529 10653021 7907874 7990266 8273558 8985016
MESH:D004487 Edema pirinixic acid 16.1312083418
MESH:D004487 Edema resveratrol 16.138985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 16.1312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8718230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 3.9817872969
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.0919294695
MESH:D004715 Endometriosis Indomethacin 8.9415652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.9410568697 9294722
MESH:D019446 Endotoxemia Indomethacin 4.4718509659
MESH:D004751 Enteritis Indomethacin 4.7210567023 16328016 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 12.2417980183
MESH:D020345 Enterocolitis, Necrotizing resveratrol 12.2417923197
MESH:D004802 Eosinophilia Indomethacin 4.0111298111
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 13.743581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 13.7420426865
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 13.7417016578
MESH:D004938 Esophageal Neoplasms Fluorouracil 13.7416337965 16481741 15173087 17638652 16785472
MESH:D004938 Esophageal Neoplasms Indomethacin 13.7411005569
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9811564622
MESH:D005234 Fatty Liver Cyclosporine 7.4319224547
MESH:D005234 Fatty Liver pirinixic acid 7.4320131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4211858732
MESH:D005334 Fever Indomethacin 4.0811852909 17627676 10431976
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.996705139
MESH:D005354 Fibrosarcoma Indomethacin 4.8610962813
MESH:D005355 Fibrosis Cyclosporine 14.5712168785 12639820
MESH:D005355 Fibrosis Indomethacin 14.5717994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.5720067830
MESH:D005499 Folliculitis Indomethacin 5.1411298111
MESH:D005756 Gastritis Indomethacin 4.7215046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.188708960
MESH:D005909 Glioblastoma Indomethacin 3.5312870263
MESH:D005910 Glioma Fluorouracil 6.1916145905
MESH:D005910 Glioma Indomethacin 6.1918371953 16487511
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.2511849393
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.007505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5710696789
MESH:D006073 Gout Indomethacin 5.3211248219
MESH:D006258 Head and Neck Neoplasms decitabine 12.8819215824
MESH:D006258 Head and Neck Neoplasms Fluorouracil 12.8815162350 15102660 18337622
MESH:D006258 Head and Neck Neoplasms Indomethacin 12.8815482327
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.4910048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 6.4916080930
MESH:D006333 Heart Failure pirinixic acid 6.8620558911
MESH:D006333 Heart Failure Selenium 6.8617162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3915720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2911000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.5315633222
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.476705139
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.6415135802
MESH:D006529 Hepatomegaly pirinixic acid 8.1316221962 19176532 19772884 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.1315340226 12621046 16120746
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6916490937 16863852
MESH:D006561 Herpes Simplex resveratrol 4.1416876885
MESH:D019584 Hot Flashes Vitamin E 3.9414716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0215340226 16959395 8697196 18606429 16354765
MESH:D006930 Hyperalgesia Indomethacin 3.7312727271
MESH:D034321 Hyperamylasemia Indomethacin 5.6917883296
MESH:D006937 Hypercholesterolemia resveratrol 3.9617188708
MESH:D006940 Hyperemia Indomethacin 4.9712524144
MESH:D006943 Hyperglycemia pirinixic acid 3.1420558911
MESH:D006949 Hyperlipidemias Indomethacin 9.3517546600
MESH:D006949 Hyperlipidemias resveratrol 9.3516873680
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.9015034207
MESH:D006973 Hypertension Cyclosporine 4.8910903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.8918670907 18850075
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.2617488730
MESH:D007077 Ileal Diseases Indomethacin 5.0010574470 18306037
MESH:D007079 Ileitis Indomethacin 5.3210651667 10647630 16133968
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.3416133044
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.6117600658
MESH:D007248 Infertility, Male marker/mechanism 11809813
MESH:D007248 Infertility, Male decitabine 3.1717581917
MESH:D007249 Inflammation Indomethacin 8.283291741 12568917 7812673
MESH:D007249 Inflammation resveratrol 8.2816366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.2812878042 12200463
MESH:D007251 Influenza, Human resveratrol 18.4716624496
MESH:D007251 Influenza, Human Selenium 18.4716624496
MESH:D007251 Influenza, Human Vitamin E 18.4716624496
MESH:D007333 Insulin Resistance pirinixic acid 2.6016306350
MESH:D007410 Intestinal Diseases Indomethacin 4.2911713966 15831440 11855677 11686837 18236018 17329856 10210152 15610444 17994277
MESH:D019586 Intracranial Hypertension Indomethacin 5.3415241188
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.999022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2916580747
MESH:D007579 Jejunal Diseases Indomethacin 5.0010574470 18306037 16133968
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.4115604871
MESH:D007674 Kidney Diseases Cyclosporine 10.008314463 18776723 10903974
MESH:D007674 Kidney Diseases Indomethacin 10.0017190690
MESH:D007674 Kidney Diseases Vitamin E 10.0012488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.8416518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 17.4516705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 17.456582329
MESH:D007680 Kidney Neoplasms Cyclosporine 17.4512371664
MESH:D007680 Kidney Neoplasms Fluorouracil 17.4516985049
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.8712228301 11703811 10320625
MESH:D007938 Leukemia decitabine 3.0519235587 18980019
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.8915631656 10785260 16572323
MESH:D007951 Leukemia, Myeloid decitabine 3.9619117987 17236224 18454857
MESH:D015470 Leukemia, Myeloid, Acute decitabine 4.1517679729 19010910 18460780 18206229 19387464 18704418
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 4.1518360721
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.4318055864
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.5516087638
MESH:D007964 Leukocytosis Indomethacin 5.3416537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.6917980183
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.6911479899
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.1715034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 6.6915298665 17724770 15366600 16570917 15492853 15086199 18371158 15744066 15479170 17881167 17465448 16009107 17666798 14659978 15339415 15161499 15099470 15793283 17196135 18637143 15081153 14643895 15942678 14726149 15763062 15798949 18210741 15571005 16042886 18629640 17432682 15383259 12925901 15504291 18239293 17203207 16270385 15369754 16169303 14568256 15138612 15723089 17640959 16603200 15842777 17201889 12918455 18567088 15864749 17534399 17198567 18237412 15067225 15591649 17036385 15577212 16627068 18364076 17348192 15733078 16544323 18672772 17719030 18095165 14709902
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 6.6918194892
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.6915474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.6912878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 6.6916169303
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 4.3717457977
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 17.787678174
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 17.7815890375 3113478
MESH:D008113 Liver Neoplasms Fluorouracil 17.7816603448 15113037 17045692 18383874
MESH:D008113 Liver Neoplasms pirinixic acid 17.7815890375 20007298 16377806
MESH:D008113 Liver Neoplasms resveratrol 17.7820405173 19073162 19812893 19321006
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.7816984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 13.912876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 13.913712494 1399818 598648 6587162
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 13.9115603536 6150874 1848544
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.9112151625
MESH:D008171 Lung Diseases Vitamin E 3.1516863852
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 6.5516061637 19555203 11884234
MESH:D008175 Lung Neoplasms Fluorouracil 6.5515246190
MESH:D008175 Lung Neoplasms Indomethacin 6.5511053908 11497255 16537180
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.5519555203 11884234
MESH:D008175 Lung Neoplasms Vitamin E 6.5511062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.7615086387
MESH:D008223 Lymphoma decitabine 3.3919470736
MESH:D016393 Lymphoma, B-Cell resveratrol 4.2617088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.8314749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.2115688416
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 10.028985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental salinomycin 10.0219682730
MESH:D008325 Mammary Neoplasms, Experimental Selenium 10.0215318939
MESH:D008545 Melanoma decitabine 3.5517785578 16505122
MESH:D008545 Melanoma resveratrol 3.5517992120
MESH:D008654 Mesothelioma Selenium 2.7715107826
MESH:D008659 Metabolic Diseases resveratrol 4.3417112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7616801185
MESH:D008881 Migraine Disorders Indomethacin 3.6411903285
MESH:D009062 Mouth Neoplasms Fluorouracil 8.7116757204 18986760
MESH:D009062 Mouth Neoplasms Indomethacin 8.7112636206
MESH:D052016 Mucositis irinotecan 4.9717159606
MESH:D009101 Multiple Myeloma decitabine 7.4018172295
MESH:D009101 Multiple Myeloma resveratrol 7.4017049120 14749477 17164350 17935668 16267019 16490592
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.8317962980
MESH:D009135 Muscular Diseases pirinixic acid 3.4716239165
MESH:D009190 Myelodysplastic Syndromes decitabine 3.3616882708 18608210 19157545 19010910
MESH:D009203 Myocardial Infarction pirinixic acid 5.6819151258
MESH:D009203 Myocardial Infarction resveratrol 5.6817188708 17125593 16456233 16525036 17015251 16317513
MESH:D017202 Myocardial Ischemia resveratrol 8.8917015251 17125593
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.8912213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.9116411023
MESH:D009205 Myocarditis resveratrol 4.7217322642
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.837678174 18551238
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 9.533581430
MESH:D009362 Neoplasm Metastasis Indomethacin 9.5311053908 11239499 16537180
MESH:D009362 Neoplasm Metastasis irinotecan 9.5318259882
MESH:D009369 Neoplasms decitabine 8.1719470736 19116145 17925555
MESH:D009369 Neoplasms Fluorouracil 8.1718239605 18600527 16928823
MESH:D009369 Neoplasms pirinixic acid 8.1717405874
MESH:D009374 Neoplasms, Experimental Indomethacin 9.2710663608 15625704
MESH:D009374 Neoplasms, Experimental resveratrol 9.278985016
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.4117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2419348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.1714600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 2.886679447
MESH:D009447 Neuroblastoma irinotecan 3.468761367
MESH:D019636 Neurodegenerative Diseases Indomethacin 8.6212349958
MESH:D019636 Neurodegenerative Diseases resveratrol 8.6217652729
MESH:D017599 Neuroectodermal Tumors irinotecan 4.698761367
MESH:D020078 Neurogenic Inflammation resveratrol 4.3617929310
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.4116436463
MESH:D009765 Obesity pirinixic acid 1.8020558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 5.146374098
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.7516049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 8.754026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.993988306
MESH:D010003 Osteoarthritis Indomethacin 3.647009135
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.2117513867
MESH:D010051 Ovarian Neoplasms decitabine 2.6319259094 19331143
MESH:D010146 Pain Indomethacin 3.4217440234 13679232 17627676 3291741
MESH:D010149 Pain, Postoperative Indomethacin 4.6518702446 12538197
MESH:D010190 Pancreatic Neoplasms decitabine 5.4019294695
MESH:D010190 Pancreatic Neoplasms Fluorouracil 5.4019003803 16929163 15113037 16500647
MESH:D010195 Pancreatitis Indomethacin 3.8817883296 15028970
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.447296757
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.6916537180
MESH:D020734 Parkinsonian Disorders Indomethacin 4.0812349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.6911903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2212520081
MESH:D010437 Peptic Ulcer Indomethacin 5.1111148446
MESH:D010518 Periodontitis Indomethacin 4.8817225004
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.446228378
MESH:D010954 Plasmacytoma Selenium 4.8615087411
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5218163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.1812371664
MESH:D047928 Premature Birth Indomethacin 5.0917000239
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 9.4716679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.4711118676 11399792 11222880 11896295
MESH:D055728 Primary Myelofibrosis decitabine 4.6917616702
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.6718626508 19082440
MESH:D011471 Prostatic Neoplasms resveratrol 2.6717675339 17804756 16731767 15767336 17718901 17636462
MESH:D011471 Prostatic Neoplasms Vitamin E 2.6715084515
MESH:D011507 Proteinuria Indomethacin 4.1211849393
MESH:D011565 Psoriasis Cyclosporine 2.2116882103
MESH:D012004 Rectal Neoplasms Fluorouracil 3.9715538739 18722050 18286688 16160472
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.5516325855
MESH:D015427 Reperfusion Injury pirinixic acid 6.5019058328
MESH:D015427 Reperfusion Injury resveratrol 6.5017058453 16314181 16317513 17520802 15827377
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8018990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.343692021
MESH:D012208 Rhabdomyosarcoma decitabine 4.3619155313
MESH:D012640 Seizures 2,6-dinitrotoluene 2.5018551238
MESH:D012871 Skin Diseases Vitamin E 2.4318709164
MESH:D012878 Skin Neoplasms resveratrol 5.658985016 15837718
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.6516192470
MESH:D013158 Splenic Diseases Dimethylnitrosamine 5.2412587719
MESH:D013272 Stomach Diseases Indomethacin 4.3818545984 17207306 16184426 15038085 18209964 16280098 16113693 15472012 10215738 10486359 17638125 17160473 10192188
MESH:D013274 Stomach Neoplasms decitabine 6.3919037991
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 6.3916033868
MESH:D013274 Stomach Neoplasms Fluorouracil 6.3917172411 17522103 17498489 18567086 19084572 16424979 16951190 18396642 19015929 15786421
MESH:D013274 Stomach Neoplasms Indomethacin 6.3915609394
MESH:D013274 Stomach Neoplasms irinotecan 6.3915723263
MESH:D013276 Stomach Ulcer Indomethacin 3.5415255614 12077510 12467913 16397915 11595415 16934674 18726076 10423059 18193104 17895592 15104355 18543354 17654042 17918041 17657623 10878458 12500499 18181030 11523592 1323529 18087811 17135157 15138204 17627676 16252198 18431645 11729361 18209962 12498302 16755016 16150113 16631530 12787963 10750652 18299717 11595431 11145282 17977527 18237397 11906479 14567935 16169175
MESH:D020521 Stroke Vitamin E 3.4816517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.4416321402
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8712697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 11.876587162 6582329 7505956 1399818 3712494
MESH:D013964 Thyroid Neoplasms decitabine 11.8717967635
MESH:D013964 Thyroid Neoplasms Indomethacin 11.8711352223 14736730 18791128
MESH:D014062 Tongue Neoplasms Fluorouracil 9.8516280240
MESH:D014062 Tongue Neoplasms resveratrol 9.8516227395
MESH:D014456 Ulcer Indomethacin 4.8617380554 10574470
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 8.2416049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 8.248074119
MESH:D001749 Urinary Bladder Neoplasms decitabine 8.2419087683 17616700
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.2810091137
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 9.4816803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 9.4817473185
MESH:D014594 Uterine Neoplasms resveratrol 4.0917044934
MESH:D014604 Uveal Neoplasms decitabine 4.8817785578
MESH:D014605 Uveitis Cyclosporine 3.961336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5712125929
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.2617488730
MESH:D014839 Vomiting Indomethacin 4.7211897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2215886252
MESH:D014985 Xerophthalmia Cyclosporine 4.4117120751
Pathway ID Pathway Name
REACT:216 DNA Repair
KEGG:03420 Nucleotide excision repair
KEGG:04141 Protein processing in endoplasmic reticulum
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA34173
    • No data
    No data
    Releated drug ID Related drug Name
    PA164748224vorinostat
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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