AutismKB 2.0

Annotation Detail for RAD51


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RAD51 ( BRCC5,HRAD51,HsRad51,HsT16930,RAD51A,RECA )
Gene Full Name: RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
Band: 15q15.1
Quick LinksEntrez ID:5888; OMIM: 179617; Uniprot ID:RAD51_HUMAN; ENSEMBL ID: ENSG00000051180; HGNC ID: 9817
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa03440Homologous recombination
hsa05212Pancreatic cancer
hsa05200Pathways in cancer
Pathway IDPathway Name
DNA Repair
Pathway IDPathway Name
200174BARD1 signaling events
No data
Pathway IDPathway Name
501013Presynaptic phase of homologous DNA pairing and strand exchange
500047Assembly of the RAD51-ssDNA nucleoprotein complex
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1934Cancer
Desease Name
ovarian cancer
CANCER
breast cancer
head and neck cancer mutagen sensitivity
No data
Desease Name
Breast cancer, susceptibility to
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C010914 2,4-diaminotoluene 2,4-diaminotoluene results in increased expression of RAD51 mRNAincreases expression 20713471
D000677 Amsacrine RAD51 protein affects the susceptibility to Amsacrineaffects response to substance 16600179
C015001 arsenite arsenite results in decreased expression of RAD51 mRNAdecreases expression 18929588
D001554 Benzene Benzene results in decreased expression of RAD51 mRNAdecreases expression 18724895
D001554 Benzene Benzene results in increased expression of RAD51 mRNAincreases expression 15342939
D001554 Benzene TRP53 protein affects the reaction [Benzene results in decreased expression of RAD51 mRNA]affects reaction|decreases expression 12928149
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of RAD51 mRNAdecreases expression 20064835
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of RAD51 mRNAincreases expression 20713471
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RAD51 mRNAdecreases expression 20382639
C006780 bisphenol A bisphenol A results in increased expression of RAD51 mRNAincreases expression 16474171
D002166 Camptothecin Camptothecin results in decreased expression of RAD51 mRNAdecreases expression 10344722
D002166 Camptothecin Camptothecin results in decreased expression of RAD51 proteindecreases expression 10344722
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of RAD51 mRNAaffects expression 17484886
D002330 Carmustine Carmustine results in decreased expression of RAD51 mRNAdecreases expression 15980968
D002699 Chlorambucil Chlorambucil results in increased expression of RAD51 proteinincreases expression 10473103
D003520 Cyclophosphamide Cyclophosphamide results in increased expression of RAD51 mRNAincreases expression 11599041
D003561 Cytarabine Cytarabine results in increased expression of RAD51 mRNAincreases expression 19194470
C014347 decitabine decitabine affects the localization of RAD51 protein modified formaffects localization 17991895
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of RAD51 mRNAincreases expression 17854601
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of RAD51 proteinincreases expression 18506893
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of RAD51 mRNA]decreases reaction|increases expression 17854601
D004317 Doxorubicin Doxorubicin affects the expression of RAD51 proteinaffects expression 17351394
D004317 Doxorubicin Doxorubicin results in decreased expression of RAD51 mRNAdecreases expression 10344722
D004317 Doxorubicin Doxorubicin results in decreased expression of RAD51 proteindecreases expression 10344722
D004958 Estradiol Estradiol results in increased expression of RAD51 mRNAincreases expression 16474171
D019833 Genistein Genistein results in increased expression of RAD51 mRNAincreases expression 16474171
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of RAD51 mRNAincreases expression 12057914
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of RAD51 mRNAincreases expression 20713471
D008767 Methylmercury Compounds Methylmercury Compounds results in decreased expression of RAD51 mRNAdecreases expression 15984772
D008767 Methylmercury Compounds Methylmercury Compounds results in increased expression of RAD51 mRNAincreases expression 15984772
D010126 Ozone TTPA protein affects the reaction [Ozone results in increased expression of RAD51 mRNA]affects reaction|increases expression 19555225
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of RAD51 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of RAD51 mRNAincreases expression 19482888
C006253 pirinixic acid pirinixic acid results in increased expression of RAD51 mRNAincreases expression 17950772
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of RAD51 mRNA]increases expression|increases reaction 17950772
D028321 Plant Preparations Plant Preparations affects the expression of RAD51 mRNAaffects expression 16046712
D011078 Polychlorinated Biphenyls Polychlorinated Biphenyls analog results in increased expression of RAD51 mRNAincreases expression 16474171
D011374 Progesterone Progesterone affects the expression of RAD51 mRNAaffects expression 17251523
D012402 Rotenone Rotenone results in increased expression of RAD51 mRNAincreases expression 18191903
C017947 sodium arsenite sodium arsenite results in decreased expression of RAD51 mRNAdecreases expression 16014739
D018038 Sodium Selenite Sodium Selenite results in decreased expression of RAD51 mRNAdecreases expression 18175754
10344722
D018038 Sodium Selenite Sodium Selenite results in decreased expression of RAD51 proteindecreases expression 10344722
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of RAD51 mRNAdecreases expression 16714409
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of RAD51 mRNAincreases expression 15667827
D014212 Tretinoin Tretinoin results in decreased expression of RAD51 mRNAdecreases expression 18230668
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 7.276195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.2715322242 11752688 14514962
MESH:D055371 Acute Lung Injury Lipopolysaccharides 8.0911850527 18653653
MESH:D055371 Acute Lung Injury pirinixic acid 8.0918653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 9.4920127859 20464547
MESH:D000230 Adenocarcinoma Doxorubicin 9.4917418594
MESH:D000230 Adenocarcinoma Estradiol 9.4911473722
MESH:D000230 Adenocarcinoma Genistein 9.4911473722
MESH:D000236 Adenoma Benzo(a)pyrene 10.186695378
MESH:D000236 Adenoma Diethylnitrosamine 10.186695378 10737359
MESH:D000236 Adenoma Methylcholanthrene 10.1810545420 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 22.2919061943 17620307 19052882 18056438 17162532 16434500
MESH:D018248 Adenoma, Liver Cell Phenobarbital 22.2917620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 22.2916434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 22.2916835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.3815276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.5917306315 16712894
MESH:D000419 Albuminuria Doxorubicin 4.2521441931
MESH:D000505 Alopecia Tretinoin 3.3715955085
MESH:D000544 Alzheimer Disease Ozone 2.3715513908
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.6811748828
MESH:D000741 Anemia, Aplastic Benzene 4.1314761424 17661222 11369114
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.7719183758
MESH:D001161 Arteriosclerosis Cyclophosphamide 4.3015014928
MESH:D001169 Arthritis, Experimental Tretinoin 2.8916412693
MESH:D001172 Arthritis, Rheumatoid Ozone 4.4015570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.4016292516
MESH:D001249 Asthma Ozone 4.6217854713 16373670
MESH:D001249 Asthma Tretinoin 4.6216456186
MESH:D050197 Atherosclerosis Methylcholanthrene 3.2711922910
MESH:D001471 Barrett Esophagus Tretinoin 4.1116935849
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.6619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.6612125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 13.6616197459 16206674
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4715340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5715746008
MESH:D001855 Bone Marrow Diseases Benzene 4.9116183116
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.3814601052
MESH:D001862 Bone Resorption bisphenol A 3.5911985600
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.0217868700
MESH:D001930 Brain Injuries Progesterone 3.9515665606 15845082 15380490
MESH:D001932 Brain Neoplasms Carmustine 8.2416187019
MESH:D001932 Brain Neoplasms Doxorubicin 8.2417150277
MESH:D001943 Breast Neoplasms marker/mechanism
MESH:D001943 Breast Neoplasms 2,4-diaminotoluene 13.7911921183
MESH:D001943 Breast Neoplasms Benzene 13.7911921183 17162533
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 13.7920146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 13.7917123778
MESH:D001943 Breast Neoplasms Cyclophosphamide 13.7916978400 11325840 17020986 17388661 18323546 12006526 15093573 18234424 15136595
MESH:D001943 Breast Neoplasms decitabine 13.7919208741 18320071
MESH:D001943 Breast Neoplasms Diethylnitrosamine 13.7917474063
MESH:D001943 Breast Neoplasms Doxorubicin 13.7917369602 15939500 15136595 15994142 19526202 18382427 11325840 18234424 17983394 18695136 16115903 16595493 18628466 16264153 16096432 15634643 15993339 16935488 15567936 16826403 16322301 15692762 17426702 15668708
MESH:D001943 Breast Neoplasms Estradiol 13.7919861407 17261762 17018787 16675129 12948864 14630087 18497071 17289903
MESH:D001943 Breast Neoplasms Genistein 13.7917200150 16873071 16541309
MESH:D001943 Breast Neoplasms Methylcholanthrene 13.7917474063
MESH:D001943 Breast Neoplasms Plant Preparations 13.7917398067
MESH:D001943 Breast Neoplasms Progesterone 13.7915562024 16175315 17614352
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 13.7920435547
MESH:D001943 Breast Neoplasms Tretinoin 13.7916166294 16443354 16873071
MESH:D016535 Bronchial Hyperreactivity Ozone 3.4417626835 18315731 16777450 15516495 19059883 18417511 14754758
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.2816813970
MESH:D002100 Cachexia Ozone 4.4316183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.1516111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.4815721981 16011737 16050911 16097048 16192424 16124888 15673190 15700767 18705752 16227642 10355542 3786805
MESH:D002276 Carcinoid Tumor Doxorubicin 4.4916051944
MESH:D002277 Carcinoma Methylcholanthrene 7.5310545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.5316835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.8416168501
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 18.8118788625
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 18.8119701751
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 18.8117173139 17428255 17138121 19822196 17978847 20935162 19701751 20084675 19171122 16681979 10672840 20524982 18788625 17162532 17055752 19052882 20727157 19335982 20214788 17761372 16288022 18506893 16878318 20101231 16502159 20007298 16328049 18691550 19208518 19519916 16569478 18210153 19418558 3581430 19539802 18785209 18971187 18978308 10737359 18056438 16935385 20432363 20514400 18494052 19919837 16830150 18665156 11831363 3084413 20512989 16779866 18393292 16698587 16540662 21159647 16807293 19394651 19383236 19107877
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 18.8118059187 17876044 16234567 16023760
MESH:D006528 Carcinoma, Hepatocellular Estradiol 18.8116924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 18.8116924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 18.8120007298 1701930 6705139 17173139 20935162
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 18.8117306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 18.811917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.6817123778
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 4.5816152834
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 6.3716201981
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 6.3716201981 1485588
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 16.8320419170
MESH:D002294 Carcinoma, Squamous Cell decitabine 16.8319215824
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 16.836189445
MESH:D002294 Carcinoma, Squamous Cell Plant Preparations 16.8317418620
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 16.8318572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 16.8316096774 16051514
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2018670907 18850075 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 3.3315811867 16364871 16731534 15476868 16109756 17351982 16278810 17007740 17974986 16455267 17924179 17519947 17928571 16242529 16612575 18627295 17382496 17329180 15792986 17308081 16952015 17131338 15505089 16269455 16651473
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.8417334414 16243910
MESH:D002318 Cardiovascular Diseases Genistein 7.1416332659
MESH:D002318 Cardiovascular Diseases Plant Preparations 7.1416862667
MESH:D016893 Carotid Stenosis Plant Preparations 5.8315158307
MESH:D002386 Cataract Tretinoin 2.9117460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 23.6120889678
MESH:D002471 Cell Transformation, Neoplastic Cytarabine 23.618243401
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 23.617505956 2727394 21159647 17174075
MESH:D002471 Cell Transformation, Neoplastic Estradiol 23.6118566989
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 23.6116192471
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 23.6119524636 20056578
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.954080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.2816129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.4619052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.4616835633
MESH:D002779 Cholestasis pirinixic acid 2.6019176532
MESH:D002822 Choriocarcinoma Tretinoin 4.8416461808
MESH:D019457 Chromosome Breakage Sodium Selenite 4.4515894690
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.3216354765 12621046 8697196 15340226 15668235
MESH:D002972 Cleft Palate Tretinoin 5.329407595
MESH:D003092 Colitis Tretinoin 3.4017035595
MESH:D003110 Colonic Neoplasms arsenite 5.5515037631
MESH:D003110 Colonic Neoplasms decitabine 5.5517616700
MESH:D003110 Colonic Neoplasms Genistein 5.5517182828
MESH:D015179 Colorectal Neoplasms decitabine 3.4418981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 3.4418802399 18259882
MESH:D015179 Colorectal Neoplasms Polychlorinated Biphenyls 3.4415531428
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8017141729 14669216
MESH:D003324 Coronary Artery Disease Plant Preparations 3.8815158307
MESH:D019465 Craniofacial Abnormalities Benzene 3.6315643154
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.6310048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.6314991402 9125849 9142499 10589399 9664655 16925845 9224671 17551590 9211117 8800419
MESH:D003556 Cystitis Cyclophosphamide 4.6710700343 17010015 18372110 16989017 15643279 18710439 18093676 15276878 18433785 12388444 18295254 11948286 18483878 16651033 16413132 10498854 12913760 12161096 17979934 16614059
MESH:D003704 Dementia Methylmercury Compounds 9.5616140633
MESH:D003704 Dementia Polychlorinated Biphenyls 9.5616140633
MESH:D003872 Dermatitis Benzene 4.4615902427
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2818249437
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.5216285004
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 3.8215331540 11751995 10990075
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 3.1218772604
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.6220387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 6.6216647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.6217107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.1519279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.1917187935
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 10.9616177239 11566570 16227642 9327722 2869522 10092053 7440962 7120509 21278145 3732212 15968718 6884620 19085960 4309450 10915739 7179309 3786805 19336974 15027814 6623471 17522070 15998439
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 10.9619107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 10.9617416283
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 10.9615131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 10.9620420201
MESH:D004362 Drug Toxicity Doxorubicin 12.5718602426
MESH:D004362 Drug Toxicity Plant Preparations 12.5711033412
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 12.5711462148
MESH:D004421 Dystonia Phenobarbital 3.721851702
MESH:D004487 Edema pirinixic acid 5.6312083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.6312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.8915322242 16714409 18230668
MESH:D004489 Edema, Cardiac Tretinoin 10.8918230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 3.4917692515
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.8019294695
MESH:D004714 Endometrial Hyperplasia Genistein 4.2816402032
MESH:D016889 Endometrial Neoplasms Doxorubicin 16.1417359293
MESH:D016889 Endometrial Neoplasms Estradiol 16.1418566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Genistein 16.1411473722
MESH:D016889 Endometrial Neoplasms Tretinoin 16.1416569247
MESH:D004715 Endometriosis Progesterone 8.0416134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.0410568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.8418037988
MESH:D019446 Endotoxemia Lipopolysaccharides 4.0915821434 17637181 15328337
MESH:D004802 Eosinophilia Cyclophosphamide 3.9211006010
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.803659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.5611558140 3922381
MESH:D004827 Epilepsy Phenobarbital 2.7320417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.286401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.957750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.713659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.8016302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.8820426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 6.8816530937
MESH:D004938 Esophageal Neoplasms Plant Preparations 6.8816510608
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.0811564622
MESH:D005124 Eye Abnormalities Tretinoin 8.0816938888 9664655
MESH:D005234 Fatty Liver arsenite 16.5218296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 16.5261145 12631006 19224547 15959796 17595544 12795759 16239168 16045604
MESH:D005234 Fatty Liver Diethylnitrosamine 16.5220387270 21071580
MESH:D005234 Fatty Liver pirinixic acid 16.5219236843 20131406
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1511858732
MESH:D005334 Fever Lipopolysaccharides 3.759205823 11852909
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.2819069698
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.6310962813 14633661
MESH:D005355 Fibrosis arsenite 18.6718296743
MESH:D005355 Fibrosis Carbon Tetrachloride 18.6718705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 18.6720067830
MESH:D005355 Fibrosis Tretinoin 18.6717994277
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.3716452187
MESH:D005909 Glioblastoma Carmustine 15.3416187019
MESH:D005909 Glioblastoma Doxorubicin 15.3417150277
MESH:D005909 Glioblastoma Genistein 15.3416598420
MESH:D005909 Glioblastoma Tretinoin 15.3417312396
MESH:D018316 Gliosarcoma Cyclophosphamide 5.2011389073
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2810696789
MESH:D006086 Graft vs Host Disease Cyclophosphamide 4.7315172196 11014644 16376943
MESH:D006258 Head and Neck Neoplasms decitabine 11.7919215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 11.7915692506
MESH:D006258 Head and Neck Neoplasms Tretinoin 11.7916096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.8416084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 10.1320471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.1310048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 10.139664655 14991402
MESH:D006331 Heart Diseases Doxorubicin 3.2716330681 16495754 18674790 12587719 17875725 18006777 16707910 17888722 16244371 16879835 16244372 14766674 16144979
MESH:D006333 Heart Failure Doxorubicin 6.4117481944
MESH:D006333 Heart Failure pirinixic acid 6.4120558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.6315692506
MESH:D006402 Hematologic Diseases Benzene 4.3716183116
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.1216366002
MESH:D006467 Hemophilia A Cyclophosphamide 4.9911918545
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0611000095
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 5.2214986274
MESH:D006505 Hepatitis Carbon Tetrachloride 3.3019900420 19110552
MESH:D006529 Hepatomegaly Phenobarbital 12.6216109766
MESH:D006529 Hepatomegaly pirinixic acid 12.6216221962 18467677 19176532 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 12.6215340226 12621046 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.7215709030
MESH:D006561 Herpes Simplex Amsacrine 5.3310809021
MESH:D006689 Hodgkin Disease Cyclophosphamide 15.4417606976 16135485
MESH:D006689 Hodgkin Disease Cytarabine 15.4416200630
MESH:D006689 Hodgkin Disease Doxorubicin 15.4417606976 18501091 15147373
MESH:D006689 Hodgkin Disease sodium arsenite 15.4412676792
MESH:D019584 Hot Flashes Estradiol 3.4417088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.7316959395 16354765 8697196 18606429 15340226
MESH:D006930 Hyperalgesia Tretinoin 2.9716870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.2216899240
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2616778211
MESH:D006943 Hyperglycemia pirinixic acid 2.9220558911
MESH:D006973 Hypertension Benzene 4.9017940673
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.9018670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.7815338365
MESH:D007154 Immune System Diseases Cyclophosphamide 5.0216076520
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.1015869954
MESH:D007248 Infertility, Male Cyclophosphamide 10.1916517039 7193160
MESH:D007248 Infertility, Male decitabine 10.1917581917
MESH:D007248 Infertility, Male sodium arsenite 10.1915346721 12646999
MESH:D007249 Inflammation Diethylnitrosamine 10.6218785209
MESH:D007249 Inflammation Lipopolysaccharides 10.6217963957 17237260 17255318 9205823 12878042
MESH:D007249 Inflammation Progesterone 10.6215869954
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 10.6212878042 12200463
MESH:D007333 Insulin Resistance bisphenol A 15.9916393666
MESH:D007333 Insulin Resistance Estradiol 15.9916393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 15.9916306350
MESH:D007333 Insulin Resistance Sodium Selenite 15.9914714311
MESH:D007410 Intestinal Diseases Tretinoin 3.4617994277
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.3417255318
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.0116580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.0117551590 15992940
MESH:D007674 Kidney Diseases Doxorubicin 9.1116775033 15699352 15369732
MESH:D007674 Kidney Diseases Estradiol 9.1115618244
MESH:D007674 Kidney Diseases sodium arsenite 9.1120008137
MESH:D007676 Kidney Failure, Chronic Doxorubicin 3.8816707910
MESH:D007680 Kidney Neoplasms Estradiol 2.7315610895
MESH:D007938 Leukemia Benzene 18.0515935818 17119257 14694614 18335105
MESH:D007938 Leukemia Cyclophosphamide 18.0510602166
MESH:D007938 Leukemia decitabine 18.0518980019 19235587
MESH:D007938 Leukemia Genistein 18.0518980019 17468513
MESH:D007938 Leukemia Tretinoin 18.0517143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.8416085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 3.3617008537 18587576 18172266 17296974 17658394 17802794
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 3.8610373061
MESH:D007951 Leukemia, Myeloid Benzene 14.4717506065
MESH:D007951 Leukemia, Myeloid decitabine 14.4718454857 19117987 17236224
MESH:D007951 Leukemia, Myeloid Tretinoin 14.4716932348 16482212 19285840
MESH:D015470 Leukemia, Myeloid, Acute Amsacrine 8.3515148258 18043129
MESH:D015470 Leukemia, Myeloid, Acute Benzene 8.3519478238
MESH:D015470 Leukemia, Myeloid, Acute decitabine 8.3518206229 19010910 19387464 18460780 18704418 17679729
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 8.3516294345 19850784 17596541
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.1518055864
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.9517712046 15748426 16823087 19225113 17107899 17506722 16891316 19075265 16788101 17301526 9834237 17361223 16140955 12679006 17294898 16766008 17649720 17368321 19642359 16935935 17217047 19029980 19035177 16331271 17339181
MESH:D007970 Leukopenia Cyclophosphamide 10.7310052129 11830472
MESH:D007970 Leukopenia Lipopolysaccharides 10.7315821434
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.099224671
MESH:D008103 Liver Cirrhosis arsenite 14.3618296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 14.3616239168 16943688 17334410 17157831 17174718 11408273 21278145 11903743 16221502
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 14.3618522880 18407596 18665156 19638242 20032147
MESH:D008103 Liver Cirrhosis Phenobarbital 14.3621047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 14.8617805973 17976157 17631135 18054572 12958196 13678700 12898905 16033810 18395914 18205269 18210741 12741479 12632514 20821823 15818738 18317297 18277467 17944888 16248980 17900296 17481882 17922224 16638106 15996030 18156304 16097048 15673190 17698563 17761835 14512876 18187930 18166357 14748882 15123356 15338365 15370692 15730626 18481824 18472332 17721639 16136751 18429990 18418968 17565644 17766677 18705752 18251166 17823541 15931870 15052691 12649538 11481614 17640975 12586293 17869086 16027843 17714472 12389079 12667390 16116963 17708605 14716496 18376398 10355542 12546737 15959796 17525996 18006644 18412020 14620537 15876570 18279442 18472094 12666154 12445421 14724832 12632512 18263696 16192424 14716833 17557913 16015684 15893842 15925388 12609069 18395095 15650968 15362042 18420326 15057751 12445418 16011737 18339082
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 14.8616439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 14.8614716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 14.8617823541
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 14.8612878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 14.8615474484
MESH:D008106 Liver Cirrhosis, Experimental Plant Preparations 14.8617724770
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 14.8612878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 14.8618397230 16248980
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.0417285989 16964402 16246199 15830285 15720792
MESH:D008107 Liver Diseases Diethylnitrosamine 6.0417034775
MESH:D008107 Liver Diseases Phenobarbital 6.0419363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8615123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.4216899240 14706259
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 20.0121137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 20.0119294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 20.0119256749 12771043 19255062 19090486 21047994 20137499 20501860 20101389 20492335 19294768 20405173 2862719 21167192 21071580 16942905 18977376 15885732 19551842 19812893 2422723 20583210 18648771 19996281 19638242 9163691 19690152 18754104 19426721 18644402 19499222 19073162 21278145 20452335 19254457 19833225 12112319 20434301 15175105 10737359 20118626 19850985 19642983 19427195 18978307
MESH:D008113 Liver Neoplasms Phenobarbital 20.0119812893 21047994 8742319 19073162 19482888 15975961
MESH:D008113 Liver Neoplasms pirinixic acid 20.0120007298 15890375 16377806
MESH:D008113 Liver Neoplasms sodium arsenite 20.0116712894 15276417
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 20.0116984957
MESH:D008114 Liver Neoplasms, Experimental Benzene 29.9112562636
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 29.9112014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 29.9119009564 17942915 19539802 17174075 2563599 18093689 19519916 18282651 16267830 21159647 9362446 19126423 18164116 18308698 18253720 19004024 18544905 18775883 16842330 17854601 3124819 18079962
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 29.9116842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 29.911399818 598648
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 29.9118308698 1399818 2563599 6150874 17172636
MESH:D008114 Liver Neoplasms, Experimental Polychlorinated Biphenyls 29.911423854
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 29.9112151625
MESH:D008171 Lung Diseases Ozone 6.8319066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 6.8319095001
MESH:D017563 Lung Diseases, Interstitial Benzene 4.4914698565
MESH:D055370 Lung Injury Lipopolysaccharides 8.2321114838
MESH:D055370 Lung Injury Ozone 8.2320417186
MESH:D008175 Lung Neoplasms arsenite 14.5716809336
MESH:D008175 Lung Neoplasms Benzene 14.5712562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 14.576695378 20464547 20869020 18569708 20135361 18520028 20064080 18816296 17053015
MESH:D008175 Lung Neoplasms Diethylnitrosamine 14.5720970405 20512841 6695378 21163286
MESH:D008175 Lung Neoplasms Doxorubicin 14.5717418594 6189445
MESH:D008175 Lung Neoplasms Methylcholanthrene 14.5716271038 6695378 9230183 1399818 20970405 21163286 16337739 10545420 7750092 11893704 17909032 15390079 20512841
MESH:D008175 Lung Neoplasms Ozone 14.577614698 8597069
MESH:D008175 Lung Neoplasms sodium arsenite 14.5716712894 15276417 19931552 17077188 17306315
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 14.5711884234 19555203
MESH:D008223 Lymphoma Benzene 21.1617119257 17584886
MESH:D008223 Lymphoma Chlorambucil 21.1610745627
MESH:D008223 Lymphoma Cyclophosphamide 21.1612854902
MESH:D008223 Lymphoma decitabine 21.1619470736
MESH:D008223 Lymphoma Doxorubicin 21.1616098063
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 9.4316675587
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 9.4314737004
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 8.1611911406
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 8.1617654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.2615621674
MESH:D015674 Mammary Neoplasms, Animal Benzene 4.1312562636
MESH:D008325 Mammary Neoplasms, Experimental 2,4-diaminotoluene 21.0011921183
MESH:D008325 Mammary Neoplasms, Experimental Benzene 21.0011921183
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 21.0015458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 21.0011807958 17203775 11408345 16891317
MESH:D008325 Mammary Neoplasms, Experimental Genistein 21.0014578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 21.0017203775 11408345
MESH:D020149 Manganese Poisoning Estradiol 4.1719453300
MESH:D008527 Medulloblastoma Tretinoin 2.6617453147
MESH:D008545 Melanoma Carmustine 9.1612393984
MESH:D008545 Melanoma decitabine 9.1617785578 16505122
MESH:D008545 Melanoma Doxorubicin 9.1616827129
MESH:D008545 Melanoma sodium arsenite 9.1619082730 16487513
MESH:D008545 Melanoma Tretinoin 9.1616752155
MESH:D008546 Melanoma, Experimental Cyclophosphamide 4.5016388313
MESH:D008569 Memory Disorders Methylmercury Compounds 4.6118436314
MESH:D008591 Meningomyelocele Tretinoin 4.1216940565
MESH:D008654 Mesothelioma Doxorubicin 2.9317638057
MESH:D008679 Metaplasia Ozone 4.7910496685
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.2215792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 8.1716381670
MESH:D009062 Mouth Neoplasms Plant Preparations 8.1717418620
MESH:D009069 Movement Disorders Methylmercury Compounds 5.0418436314
MESH:D052016 Mucositis Doxorubicin 4.4817415656
MESH:D009101 Multiple Myeloma Benzene 6.8517119195
MESH:D009101 Multiple Myeloma decitabine 6.8518172295
MESH:D009135 Muscular Diseases pirinixic acid 3.2016239165
MESH:D009190 Myelodysplastic Syndromes decitabine 6.8918608210 16882708 19157545 19010910
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.8917596541
MESH:D009203 Myocardial Infarction Doxorubicin 8.7119429709 15857846
MESH:D009203 Myocardial Infarction Genistein 8.7117141266
MESH:D009203 Myocardial Infarction pirinixic acid 8.7119151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.7812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 12.8116810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 12.8117141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 12.8116411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.1617484760
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.459029167 3581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 5.4518259882
MESH:D009369 Neoplasms Benzo(a)pyrene 17.7611141357
MESH:D009369 Neoplasms Cyclophosphamide 17.7618854779
MESH:D009369 Neoplasms decitabine 17.7619470736 19116145 17925555
MESH:D009369 Neoplasms pirinixic acid 17.7617405874
MESH:D009369 Neoplasms sodium arsenite 17.7611559025
MESH:D009369 Neoplasms Tretinoin 17.7616594593 16946489
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.3720056578
MESH:D009389 Neovascularization, Pathologic arsenite 9.1215738583
MESH:D009389 Neovascularization, Pathologic Estradiol 9.1217289903
MESH:D009401 Nephrosis Doxorubicin 4.4616899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.7416889571 15640375
MESH:D009410 Nerve Degeneration Rotenone 3.6515790535 18619942 17356569
MESH:D009421 Nervous System Malformations bisphenol A 27.5916427766 11399458
MESH:D009421 Nervous System Malformations Estradiol 27.5916427766 11399458
MESH:D009421 Nervous System Malformations Genistein 27.5916427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 27.5914600291
MESH:D009421 Nervous System Malformations Tretinoin 27.599125849
MESH:D009436 Neural Tube Defects Benzene 11.0615643154
MESH:D009436 Neural Tube Defects sodium arsenite 11.0612854658
MESH:D009436 Neural Tube Defects Tretinoin 11.069142499
MESH:D009447 Neuroblastoma Cyclophosphamide 6.688761367 16115947 15176712
MESH:D009447 Neuroblastoma Doxorubicin 6.6815555623
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.0920387270
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 4.588761367 12837982
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.8020387270
MESH:D009503 Neutropenia Cyclophosphamide 4.048291058
MESH:D009765 Obesity pirinixic acid 1.7420558911
MESH:D009784 Occupational Diseases Benzene 3.9115727169 15935809 15612468 17479406 15913788 17119257 17178637 16737584 15576619
MESH:D009845 Oligospermia Cyclophosphamide 4.4016517039
MESH:D010018 Osteomalacia Phenobarbital 4.0517016548
MESH:D010024 Osteoporosis Genistein 3.0619401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.8016169203
MESH:D012516 Osteosarcoma Doxorubicin 3.8715930896
MESH:D010049 Ovarian Diseases bisphenol A 4.6811985600
MESH:D010051 Ovarian Neoplasms Benzene 21.3512562636
MESH:D010051 Ovarian Neoplasms decitabine 21.3519331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 21.3519401270
MESH:D010051 Ovarian Neoplasms Genistein 21.3519005980
MESH:D010051 Ovarian Neoplasms Progesterone 21.3516525653 17393432
MESH:D010051 Ovarian Neoplasms sodium arsenite 21.3517306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 21.3516936753
MESH:D010146 Pain Cyclophosphamide 6.2218093676 12161096
MESH:D010146 Pain Tretinoin 6.2216870215
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 15.0911332152
MESH:D010190 Pancreatic Neoplasms decitabine 15.0919294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 15.0916540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 15.0916965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 15.0915976015
MESH:D010300 Parkinson Disease Polychlorinated Biphenyls 5.3916702228
MESH:D010300 Parkinson Disease Rotenone 5.3918191903 16412576 16140633 11535288 15451049 19232380 19114014 11445065 18619942
MESH:D020734 Parkinsonian Disorders Rotenone 3.8115927086 15574749 15795934 18197244
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9312520081
MESH:D010538 Peritonitis Ozone 3.8316369182
MESH:D003557 Phyllodes Tumor Doxorubicin 4.8417983394
MESH:D010997 Pleural Neoplasms Doxorubicin 4.8417638057
MESH:D011014 Pneumonia Lipopolysaccharides 10.0712224865 11605937
MESH:D011014 Pneumonia Ozone 10.0718007984 18381685 18929643
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2618163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.232563599
MESH:D011230 Precancerous Conditions Phenobarbital 8.232563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 7.5621297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cytarabine 7.5621297632
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 14.6010548101
MESH:D011297 Prenatal Exposure Delayed Effects Methylmercury Compounds 14.6018436314
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 14.6011118676 11896295 11399792 11222880
MESH:D055728 Primary Myelofibrosis decitabine 4.4217616702
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.6320887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.6320887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.8417292933
MESH:D011471 Prostatic Neoplasms bisphenol A 2.8416740699
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 2.8417136230
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.8415749863 16729912 16888761 15897917 16868541 18437689
MESH:D011471 Prostatic Neoplasms Estradiol 2.8416740699
MESH:D011471 Prostatic Neoplasms Genistein 2.8416925846 15378649 15256057
MESH:D011471 Prostatic Neoplasms Polychlorinated Biphenyls 2.8415721890
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.8416039940
MESH:D011471 Prostatic Neoplasms Sodium Selenite 2.8418760546
MESH:D011507 Proteinuria Tretinoin 3.3216636307
MESH:D019310 Pseudolymphoma Phenobarbital 4.1812752131
MESH:D011625 Pterygium Tretinoin 4.4816723453
MESH:D011629 Puberty, Precocious bisphenol A 4.4710548101
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 3.1616636934
MESH:D051437 Renal Insufficiency Doxorubicin 3.9217922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.2319058328
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.5310835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5418990726
MESH:D012208 Rhabdomyosarcoma decitabine 9.9919155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 9.9916283617 16116481
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7418045962
MESH:D012509 Sarcoma Doxorubicin 3.7216767912 15675481 15625365 17203757 17710206 18313854
MESH:D012512 Sarcoma, Ewing's Doxorubicin 3.9514601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.4817846226
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 4.5316636934
MESH:D012640 Seizures Phenobarbital 2.4916876388 3137016 11442880 4039156
MESH:D003294 Seizures, Febrile Phenobarbital 4.516407741
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 16.3319755658 10029692
MESH:D012878 Skin Neoplasms Doxorubicin 16.3315692506
MESH:D012878 Skin Neoplasms sodium arsenite 16.3319524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 16.3316192470
MESH:D012878 Skin Neoplasms Tretinoin 16.3316467112
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.2617203757 16767912 15625365
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 5.2016517039
MESH:D013119 Spinal Cord Injuries Progesterone 3.9716503802 15862959
MESH:D016135 Spinal Dysraphism sodium arsenite 3.5612854658
MESH:D013274 Stomach Neoplasms Benzene 6.0312562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 6.032093021 20155912
MESH:D013274 Stomach Neoplasms decitabine 6.0319037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 6.0318456281
MESH:D013274 Stomach Neoplasms Tretinoin 6.0317261132
MESH:D019966 Substance-Related Disorders bisphenol A 3.6716045194 16684133
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 4.7512837982
MESH:D024801 Tauopathies Camptothecin 5.3116930453
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.9015821434
MESH:D013953 Thymus Neoplasms Benzene 4.6410850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5912697716
MESH:D013964 Thyroid Neoplasms decitabine 20.0017967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 20.007505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 20.0016010429 17909728
MESH:D013964 Thyroid Neoplasms Phenobarbital 20.001399818
MESH:D013964 Thyroid Neoplasms Tretinoin 20.0016026305 17045167
MESH:D013978 Tibial Fractures Estradiol 4.3719048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.5216051514
MESH:D014376 Tuberculosis Tretinoin 3.0416040207
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 18.2617053015
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 18.2614692829
MESH:D001749 Urinary Bladder Neoplasms decitabine 18.2619087683 17616700
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 18.2617653716
MESH:D001749 Urinary Bladder Neoplasms Plant Preparations 18.2611251952
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 18.2611723127 16712894 16452187 17306315
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 8.5211813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.5216129372
MESH:D014591 Uterine Diseases bisphenol A 4.6914652134
MESH:D014594 Uterine Neoplasms Benzene 4.0412562636
MESH:D014604 Uveal Neoplasms decitabine 11.7717785578
MESH:D014604 Uveal Neoplasms Tretinoin 11.7716752155
MESH:D014652 Vascular Diseases sodium arsenite 4.1117056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2812125929
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.9217678736 16364871 17334414 17638931
MESH:D014820 Vitiligo Tretinoin 3.7616761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9315886252
MESH:D009396 Wilms Tumor Tretinoin 3.7116287080
Pathway ID Pathway Name
REACT:216 DNA Repair
KEGG:03440 Homologous recombination
REACT:27271 Meiotic Recombination
REACT:27235 Meiotic Recombination (mouse)
KEGG:05212 Pancreatic cancer
KEGG:05200 Pathways in cancer
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA34176
    • No data
    Releated disease ID Related disease Name
    PA443560Breast Neoplasms
    PA445503Rectal Neoplasms
    Releated drug ID Related drug Name
    PA164713220Pyrimidine analogues
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB04395 - Phosphoaminophosphonic Acid-Adenylate Ester
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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