AutismKB 2.0

Annotation Detail for RAF1


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Basic Information Top
Gene Symbol:RAF1 ( CRAF,NS5,Raf-1,c-Raf )
Gene Full Name: v-raf-1 murine leukemia viral oncogene homolog 1
Band: 3p25.2
Quick LinksEntrez ID:5894; OMIM: 164760; Uniprot ID:RAF1_HUMAN; ENSEMBL ID: ENSG00000132155; HGNC ID: 9829
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY66-14MAP kinase cascade
Pathway IDPathway Name
hsa04914Progesterone-mediated oocyte maturation
hsa05160Hepatitis C
hsa04270Vascular smooth muscle contraction
hsa04912GnRH signaling pathway
hsa04910Insulin signaling pathway
hsa04916Melanogenesis
hsa04012ErbB signaling pathway
hsa04010MAPK signaling pathway
hsa04720Long-term potentiation
hsa04650Natural killer cell mediated cytotoxicity
hsa04540Gap junction
hsa04730Long-term depression
hsa05219Bladder cancer
hsa04722Neurotrophin signaling pathway
hsa05211Renal cell carcinoma
hsa05223Non-small cell lung cancer
hsa05221Acute myeloid leukemia
hsa05220Chronic myeloid leukemia
hsa04810Regulation of actin cytoskeleton
hsa05218Melanoma
hsa05212Pancreatic cancer
hsa05213Endometrial cancer
hsa05210Colorectal cancer
hsa05214Glioma
hsa05215Prostate cancer
hsa04510Focal adhesion
hsa04062Chemokine signaling pathway
hsa04370VEGF signaling pathway
hsa05200Pathways in cancer
hsa04660T cell receptor signaling pathway
hsa04662B cell receptor signaling pathway
hsa04664Fc epsilon RI signaling pathway
hsa04666Fc gamma R-mediated phagocytosis
Pathway IDPathway Name
Synaptic Transmission
Signalling by NGF
Axon guidance
Hemostasis
Signaling by EGFR
Signaling by Insulin receptor
Signaling by PDGF
Signaling in Immune system
Pathway IDPathway Name
200182Trk receptor signaling mediated by the MAPK pathway
200184Downstream signaling in naive CD8+ T cells
200032Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
200003Fc-epsilon receptor I signaling in mast cells
200004Endothelins
200005BCR signaling pathway
200135p38 signaling mediated by MAPKAP kinases
200156Signaling events mediated by Stem cell factor receptor (c-Kit)
200015GMCSF-mediated signaling events
200146Internalization of ErbB1
200088Ras signaling in the CD4+ TCR pathway
200080mTOR signaling pathway
200082IL2-mediated signaling events
200084IGF1 pathway
200145Nongenotropic Androgen signaling
200150CXCR3-mediated signaling events
200169Class I PI3K signaling events mediated by Akt
200119ErbB2/ErbB3 signaling events
200113ErbB1 downstream signaling
200100Ceramide signaling pathway
200192Signaling events mediated by focal adhesion kinase
200191Regulation of retinoblastoma protein
200057CDC42 signaling events
Pathway IDPathway Name
P00053T cell activation
P00056VEGF signaling pathway
P00019Endothelin signaling pathway
P00018EGF receptor signaling pathway
P00005Angiogenesis
P00010B cell activation
P00047PDGF signaling pathway
P00021FGF signaling pathway
P00034Integrin signalling pathway
P00032Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade
P00036Interleukin signaling pathway
P00031Inflammation mediated by chemokine and cytokine signaling pathway
P04393Ras Pathway
Pathway IDPathway Name
500177CREB phophorylation through the activation of Ras
500080RAF activation
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1990Skin disease, Genetic
1740Alzheimer's disease
1797Vitamin D deficiency
1850Herpes
1934Cancer
2247Osteomyelitis
No data
No data
Desease Name
LEOPARD syndrome 2
Noonan syndrome 5
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C112765 17-(allylamino)-17-demethoxygeldanamycin 17-(allylamino)-17-demethoxygeldanamycin results in decreased expression of RAF1 proteindecreases expression 10564678
C436083 2-(2-oxo-2-((3,7,11-trimethyl-2,6,10-dodecatrienyl)oxy)aminoethyl)phosphonic acid, (2,2-dimethyl-1-oxopropoxy)methyl ester sodium 2-(2-oxo-2-((3,7,11-trimethyl-2,6,10-dodecatrienyl)oxy)aminoethyl)phosphonic acid, (2,2-dimethyl-1-oxopropoxy)methyl ester sodium inhibits the reaction [ammonium trichloro(dioxoethylene-O,O'-)tellurate results in increased phosphorylation of and results in increased activity of RAF1 protein]decreases reaction|increases activity|increases phosphorylation 14656992
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of RAF1 mRNAaffects expression 21346803
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Phosphates results in increased phosphorylation of RAF1 protein]decreases reaction|increases phosphorylation 16763222
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane affects the expression of RAF1 mRNAaffects expression 18648102
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of RAF1 mRNAaffects expression 21346803
C108123 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine results in decreased expression of RAF1 protein modified formdecreases expression 17492661
D000082 Acetaminophen Acetaminophen affects the expression of RAF1 mRNAaffects expression 17562736
C031143 AICA ribonucleotide RAF1 protein affects the reaction [AICA ribonucleotide results in increased uptake of Deoxyglucose]affects reaction|increases uptake 11978788
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RAF1 mRNAaffects expression 16483693
C054105 ammonium trichloro(dioxoethylene-O,O'-)tellurate 2-(2-oxo-2-((3,7,11-trimethyl-2,6,10-dodecatrienyl)oxy)aminoethyl)phosphonic acid, (2,2-dimethyl-1-oxopropoxy)methyl ester sodium inhibits the reaction [ammonium trichloro(dioxoethylene-O,O'-)tellurate results in increased phosphorylation of and results in increased activity of RAF1 protein]decreases reaction|increases activity|increases phosphorylation 14656992
C054105 ammonium trichloro(dioxoethylene-O,O'-)tellurate ammonium trichloro(dioxoethylene-O,O'-)tellurate results in increased phosphorylation of and results in increased activity of RAF1 proteinincreases activity|increases phosphorylation 14656992
C006632 arsenic trioxide arsenic trioxide results in increased expression of RAF1 mRNAincreases expression 20458559
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RAF1 mRNAdecreases expression 19150397
C070515 bisindolylmaleimide I bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RAF1 protein]decreases reaction|increases activity 14623285
C400082 bortezomib [bortezomib co-treated with Butyrates] results in decreased expression of RAF1 proteinaffects cotreatment|decreases expression 12893773
C400082 bortezomib [bortezomib co-treated with vorinostat] results in decreased expression of RAF1 proteinaffects cotreatment|decreases expression 12893773
D002087 Butyrates [bortezomib co-treated with Butyrates] results in decreased expression of RAF1 proteinaffects cotreatment|decreases expression 12893773
D002087 Butyrates Butyrates results in decreased expression of RAF1 proteindecreases expression 12893773
D000001 Calcimycin Calcimycin results in increased phosphorylation of and results in increased activity of RAF1 proteinincreases activity|increases phosphorylation 16000378
D020111 Chlorodiphenyl (54% Chlorine) Chlorodiphenyl (54% Chlorine) results in increased expression of RAF1 mRNAincreases expression 8471063
C488583 Clostridium difficile lethal toxin B Clostridium difficile lethal toxin B inhibits the reaction [EDN1 protein results in increased phosphorylation of RAF1 protein]decreases reaction|increases phosphorylation 11158304
C488583 Clostridium difficile lethal toxin B Clostridium difficile lethal toxin B results in decreased phosphorylation of RAF1 proteindecreases phosphorylation 11158304
C017160 cypermethrin cypermethrin promotes the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]affects cotreatment|increases activity|increases reaction 14623285
D003847 Deoxyglucose RAF1 protein affects the reaction [AICA ribonucleotide results in increased uptake of Deoxyglucose]affects reaction|increases uptake 11978788
C084037 dephostatin dephostatin promotes the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]affects cotreatment|increases activity|increases reaction 14623285
D004026 Dieldrin Dieldrin results in increased phosphorylation of and results in increased activity of RAF1 proteinincreases activity|increases phosphorylation 15888667
D004052 Diethylnitrosamine [troglitazone co-treated with Diethylnitrosamine] results in decreased expression of RAF1 mRNAaffects cotreatment|decreases expression 18597072
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased expression of RAF1 proteinincreases expression 19555203
11884234
D004128 Dimethylnitrosamine Tetrachlorodibenzodioxin promotes the reaction [Dimethylnitrosamine results in increased expression of RAF1 protein]increases expression|increases reaction 19555203
11884234
C067311 docetaxel docetaxel results in increased expression of RAF1 proteinincreases expression 15970518
D004642 Emodin Emodin results in decreased expression of RAF1 mRNAdecreases expression 16045814
D004642 Emodin Emodin inhibits the reaction [PDGFB protein results in increased phosphorylation of RAF1 protein]decreases reaction|increases phosphorylation 15288473
D004726 Endosulfan Endosulfan results in increased phosphorylation of and results in increased activity of RAF1 proteinincreases activity|increases phosphorylation 15888667
C074283 estradiol 3-benzoate estradiol 3-benzoate results in decreased phosphorylation of RAF1 proteindecreases phosphorylation 15778002
D004958 Estradiol Estradiol results in decreased expression of RAF1 mRNAdecreases expression 16029874
D004958 Estradiol Estradiol results in increased activity of RAF1 proteinincreases activity 12432273
D004958 Estradiol Estradiol results in increased phosphorylation of RAF1 proteinincreases phosphorylation 15930183
D005419 Flavonoids Flavonoids results in increased expression of RAF1 mRNAincreases expression 18035473
D005472 Fluorouracil Fluorouracil results in increased expression of RAF1 mRNAincreases expression 15152939
D005492 Folic Acid Folic Acid affects the expression of RAF1 mRNAaffects expression 16361273
D005576 Forskolin Forskolin results in decreased activity of RAF1 proteindecreases activity 14975937
C001277 geldanamycin geldanamycin results in increased expression of RAF1 proteinincreases expression 8816498
C001277 geldanamycin geldanamycin results in increased degradation of RAF1 proteinincreases degradation 8816498
D019833 Genistein Genistein results in decreased phosphorylation of RAF1 proteindecreases phosphorylation 15781664
D006533 Heptachlor Heptachlor results in increased phosphorylation of and results in increased activity of RAF1 proteinincreases activity|increases phosphorylation 15888667
D006861 Hydrogen Peroxide cypermethrin promotes the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]affects cotreatment|increases activity|increases reaction 14623285
D006861 Hydrogen Peroxide dephostatin promotes the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]affects cotreatment|increases activity|increases reaction 14623285
D006861 Hydrogen Peroxide [Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 proteinaffects cotreatment|increases activity 14623285
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased activity of RAF1 proteinincreases activity 14623285
D006861 Hydrogen Peroxide Okadaic Acid inhibits the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]affects cotreatment|decreases reaction|increases activity 14623285
D006861 Hydrogen Peroxide tautomycin inhibits the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]affects cotreatment|decreases reaction|increases activity 14623285
C078038 inchinko-to inchinko-to inhibits the reaction [PDGFB protein results in increased phosphorylation of RAF1 protein]decreases reaction|increases phosphorylation 15288473
C456099 KF58333 KF58333 results in decreased expression of RAF1 proteindecreases expression 11800023
C067431 letrozole letrozole results in increased expression of RAF1 proteinincreases expression 15967659
D001556 Lindane Lindane results in increased phosphorylation of and results in increased activity of RAF1 proteinincreases activity|increases phosphorylation 15888667
C009900 lipoteichoic acid lipoteichoic acid results in increased phosphorylation of RAF1 proteinincreases phosphorylation 19573522
C009900 lipoteichoic acid Propofol inhibits the reaction [lipoteichoic acid results in increased phosphorylation of RAF1 protein]decreases reaction|increases phosphorylation 19573522
C009900 lipoteichoic acid TLR2 protein affects the reaction [lipoteichoic acid results in increased phosphorylation of RAF1 protein]affects reaction|increases phosphorylation 19573522
C013592 mangiferin mangiferin results in decreased expression of RAF1 mRNAdecreases expression 15135318
D009151 Mustard Gas Mustard Gas results in increased phosphorylation of and results in increased activity of RAF1 proteinincreases activity|increases phosphorylation 18200059
C031721 naphthalene naphthalene results in increased expression of RAF1 proteinincreases expression 14595851
C404397 NSC 680410 NSC 680410 results in decreased expression of RAF1 proteindecreases expression 14647418
D019319 Okadaic Acid Okadaic Acid inhibits the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]affects cotreatment|decreases reaction|increases activity 14623285
C440229 Oleylethanolamide Oleylethanolamide results in increased activity of RAF1 proteinincreases activity 16269455
D017239 Paclitaxel [pifithrin co-treated with Paclitaxel] results in increased phosphorylation of RAF1 proteinaffects cotreatment|increases phosphorylation 18516295
D010656 Phenylephrine RAF1 protein affects the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]affects reaction|increases phosphorylation 17976640
D010656 Phenylephrine RAF1 protein affects the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]affects reaction|increases phosphorylation 17976640
D010710 Phosphates 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Phosphates results in increased phosphorylation of RAF1 protein]decreases reaction|increases phosphorylation 16763222
D010710 Phosphates Phosphates results in increased phosphorylation of and results in increased activity of RAF1 proteinincreases activity|increases phosphorylation 16763222
C121565 pifithrin [pifithrin co-treated with Paclitaxel] results in increased phosphorylation of RAF1 proteinaffects cotreatment|increases phosphorylation 18516295
D011374 Progesterone Progesterone results in decreased phosphorylation of RAF1 proteindecreases phosphorylation 17492661
D015742 Propofol Propofol inhibits the reaction [lipoteichoic acid results in increased phosphorylation of RAF1 protein]decreases reaction|increases phosphorylation 19573522
C085746 rottlerin rottlerin results in decreased phosphorylation of RAF1 proteindecreases phosphorylation 15949478
C085746 rottlerin rottlerin results in decreased phosphorylation of RAF1 proteindecreases phosphorylation 15949478
D012643 Selenium Selenium results in increased phosphorylation of and results in increased activity of RAF1 proteinincreases activity|increases phosphorylation 18583539
C009250 sevoflurane sevoflurane affects the expression of RAF1 mRNAaffects expression 15967596
C017947 sodium arsenite sodium arsenite results in decreased expression of RAF1 mRNAdecreases expression 19822182
D020058 Styrene Styrene results in increased expression of RAF1 proteinincreases expression 15212811
C452601 sulindac derivative IND 12 sulindac derivative IND 12 results in decreased activity of RAF1 proteindecreases activity 11912145
C053079 tautomycin tautomycin inhibits the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]affects cotreatment|decreases reaction|increases activity 14623285
D013739 Testosterone Testosterone results in increased activity of RAF1 proteinincreases activity 20372086
D013739 Testosterone [Testosterone results in increased activity of RAF1 protein] which results in increased activity of MAP2K1 proteinincreases activity 20372086
D013739 Testosterone [Testosterone results in increased activity of RAF1 protein] which results in increased activity of MAPK1 proteinincreases activity 20372086
D013739 Testosterone [Testosterone results in increased activity of RAF1 protein] which results in increased activity of MAPK3 proteinincreases activity 20372086
D013739 Testosterone [Testosterone results in increased activity of RAF1 protein] which results in increased activity of MYC proteinincreases activity 20372086
D013739 Testosterone [Testosterone results in increased activity of RAF1 protein] which results in increased activity of RPS6KB1 proteinincreases activity 20372086
D013739 Testosterone [Testosterone results in increased activity of RAF1 protein] which results in increased activity of STAT5 proteinincreases activity 20372086
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin affects the localization of RAF1 proteinaffects localization 19555203
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin promotes the reaction [Dimethylnitrosamine results in increased expression of RAF1 protein]increases expression|increases reaction 11884234
19555203
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of RAF1 mRNAincreases expression 19465110
D013755 Tetradecanoylphorbol Acetate RAF1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]affects reaction|increases phosphorylation 17976640
D013755 Tetradecanoylphorbol Acetate RAF1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]affects reaction|increases phosphorylation 17976640
D013755 Tetradecanoylphorbol Acetate RAF1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MTOR protein]affects reaction|increases phosphorylation 17976640
D013755 Tetradecanoylphorbol Acetate RAF1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KB1 protein]affects reaction|increases phosphorylation 17976640
D013755 Tetradecanoylphorbol Acetate bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RAF1 protein]decreases reaction|increases activity 14623285
D013755 Tetradecanoylphorbol Acetate cypermethrin promotes the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]affects cotreatment|increases activity|increases reaction 14623285
D013755 Tetradecanoylphorbol Acetate dephostatin promotes the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]affects cotreatment|increases activity|increases reaction 14623285
D013755 Tetradecanoylphorbol Acetate [Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 proteinaffects cotreatment|increases activity 14623285
D013755 Tetradecanoylphorbol Acetate Okadaic Acid inhibits the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]affects cotreatment|decreases reaction|increases activity 14623285
D013755 Tetradecanoylphorbol Acetate PRKCE protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of RAF1 protein]increases activity|increases reaction 14623285
D013755 Tetradecanoylphorbol Acetate tautomycin inhibits the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]affects cotreatment|decreases reaction|increases activity 14623285
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased activity of RAF1 proteinincreases activity 14623285
C402769 tipifarnib tipifarnib results in increased expression of RAF1 mRNAincreases expression 16403772
C113106 tocopheryloxybutyric acid tocopheryloxybutyric acid inhibits the reaction [Urethane promotes the reaction [RAF1 protein binds to HRAS1 protein]]affects binding|decreases reaction|increases reaction 11062179
C057693 troglitazone [troglitazone co-treated with Diethylnitrosamine] results in decreased expression of RAF1 mRNAaffects cotreatment|decreases expression 18597072
D014520 Urethane tocopheryloxybutyric acid inhibits the reaction [Urethane promotes the reaction [RAF1 protein binds to HRAS1 protein]]affects binding|decreases reaction|increases reaction 11062179
D014520 Urethane Urethane promotes the reaction [RAF1 protein binds to HRAS1 protein]affects binding|increases reaction 11062179
D014520 Urethane Vitamin E inhibits the reaction [Urethane promotes the reaction [RAF1 protein binds to HRAS1 protein]]affects binding|decreases reaction|increases reaction 11062179
D014810 Vitamin E Vitamin E inhibits the reaction [Urethane promotes the reaction [RAF1 protein binds to HRAS1 protein]]affects binding|decreases reaction|increases reaction 11062179
C111237 vorinostat [bortezomib co-treated with vorinostat] results in decreased expression of RAF1 proteinaffects cotreatment|decreases expression 12893773
C111237 vorinostat vorinostat results in decreased expression of RAF1 proteindecreases expression 16144943
12893773
C088658 zoledronic acid zoledronic acid results in decreased expression of RAF1 proteindecreases expression 12799645
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 6.177525203
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.1715322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 2.8618287403
MESH:D058186 Acute Kidney Injury Folic Acid 11.1216316344 16595132 17003819
MESH:D058186 Acute Kidney Injury pifithrin 11.1217670903
MESH:D058186 Acute Kidney Injury zoledronic acid 11.1219715164
MESH:D000210 Acute-Phase Reaction zoledronic acid 4.7720200999
MESH:D000230 Adenocarcinoma arsenic trioxide 13.9111798837 19825857
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 13.9116033868
MESH:D000230 Adenocarcinoma Estradiol 13.9111473722
MESH:D000230 Adenocarcinoma Fluorouracil 13.9117638652
MESH:D000230 Adenocarcinoma Genistein 13.9111473722
MESH:D000230 Adenocarcinoma Urethane 13.9118316556
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Urethane 4.9915814487
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 16.233712494
MESH:D000236 Adenoma Diethylnitrosamine 16.236695378 10737359
MESH:D000236 Adenoma Dimethylnitrosamine 16.2319555203
MESH:D000236 Adenoma Folic Acid 16.2316963246
MESH:D000236 Adenoma Urethane 16.2316926031 17093202 6695378 10530776 10822126 11497255 17195641
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 7.7219061943 16434500 18056438 19052882 17620307 17162532
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 7.7216835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.9815276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.1816712894 17306315
MESH:D000382 Agricultural Workers' Diseases cypermethrin 10.7916487989
MESH:D000382 Agricultural Workers' Diseases Heptachlor 10.7912661182
MESH:D000382 Agricultural Workers' Diseases Lindane 10.7912661182
MESH:D000544 Alzheimer Disease Folic Acid 2.8617116317
MESH:D000707 Anaphylaxis mangiferin 4.7816536907 14669257
MESH:D000740 Anemia Fluorouracil 6.6215504547 16511603 17963324
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.6211748828
MESH:D000799 Angioedema Acetaminophen 3.1210982225
MESH:D000987 Antisocial Personality Disorder Testosterone 5.137506515
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.5017460149
MESH:D001249 Asthma Mustard Gas 2.4610378619
MESH:D050197 Atherosclerosis mangiferin 3.6518450471
MESH:D001321 Autistic Disorder Acetaminophen 2.1818445737
MESH:D001321 Autistic Disorder Folic Acid 2.1821388746
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.301440618 11289319
MESH:D001768 Blister Mustard Gas 4.4519167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 6.8516206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 6.8512125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.0715340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.2715746008
MESH:D001859 Bone Neoplasms Paclitaxel 8.6615867366
MESH:D001859 Bone Neoplasms zoledronic acid 8.6616778634 16121404 15867366 19442620 17312309 11697798
MESH:D001862 Bone Resorption mangiferin 8.079881647
MESH:D001862 Bone Resorption zoledronic acid 8.078053405 18404659 16769263 15845617 18496637 11869084
MESH:D001919 Bradycardia Phenylephrine 3.8415306635
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.6217868700
MESH:D001930 Brain Injuries Progesterone 3.5715845082 15380490 15665606
MESH:D001943 Breast Neoplasms therapeutic 12432273
MESH:D001943 Breast Neoplasms Deoxyglucose 16.9918985042
MESH:D001943 Breast Neoplasms Dieldrin 16.9915770527 11859874
MESH:D001943 Breast Neoplasms Diethylnitrosamine 16.9917474063
MESH:D001943 Breast Neoplasms docetaxel 16.9915692762 18628466 15567936 16264153 16495393 17369602 19526202
MESH:D001943 Breast Neoplasms Estradiol 16.9917018787 12948864 16675129 14630087 17289903 17261762 18497071 19861407
MESH:D001943 Breast Neoplasms Fluorouracil 16.9919217205 18357371 15136595 16557594 16595493 16110121 18608205
MESH:D001943 Breast Neoplasms Folic Acid 16.9916777985
MESH:D001943 Breast Neoplasms Genistein 16.9916873071 16541309 17200150
MESH:D001943 Breast Neoplasms Heptachlor 16.998738476
MESH:D001943 Breast Neoplasms letrozole 16.9917892469 16002280
MESH:D001943 Breast Neoplasms Lindane 16.9914688026
MESH:D001943 Breast Neoplasms Paclitaxel 16.9918234424 16244791 16115903 18323546 11325840 16273361 15136595 18223236
MESH:D001943 Breast Neoplasms Progesterone 16.9915562024 16175315 17614352
MESH:D001943 Breast Neoplasms Styrene 16.9915986119
MESH:D001943 Breast Neoplasms Testosterone 16.9917261762
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 16.9920435547
MESH:D001943 Breast Neoplasms vorinostat 16.9916144943
MESH:D001943 Breast Neoplasms zoledronic acid 16.9916096432 18695136
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.4515286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.2617687719 10378619
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.6711589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.7616111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.2516050911
MESH:D002276 Carcinoid Tumor Fluorouracil 3.9516051944
MESH:D002277 Carcinoma Dimethylnitrosamine 10.6719555203
MESH:D002277 Carcinoma Fluorouracil 10.6717121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 10.6716835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 19.1516705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 19.157296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 19.153084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 19.1516217749 14691202 15553829 11135700 15073043
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 19.1520512989 19539802 20007298 3084413 16830150 18210153 20524982 16935385 16698587 17978847 16681979 17428255 20514400 20084675 20101231 20214788 19383236 18506893 19822196 3581430 18691550 18785209 10737359 20935162 16502159 19701751 16779866 18788625 18971187 10672840 18978308 19919837 18494052 16878318 16540662 19208518 18056438 19519916 20432363 19052882 20727157 17055752 19107877 16288022 17162532 17173139 11831363 17761372 19418558 16569478 16328049 18393292 18665156 19394651 21159647 16807293 19171122 17138121 19335982
MESH:D006528 Carcinoma, Hepatocellular Estradiol 19.1516924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 19.1516799960 16332177 17971768 17045692 18930000 17088986
MESH:D006528 Carcinoma, Hepatocellular Genistein 19.1516924424
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 19.1516313753
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 19.1517306315 15276417 16507464
MESH:D002289 Carcinoma, Non-Small-Cell Lung bortezomib 7.5916052434
MESH:D002289 Carcinoma, Non-Small-Cell Lung docetaxel 7.5911894018
MESH:D002289 Carcinoma, Non-Small-Cell Lung zoledronic acid 7.5919233551
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.1519014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 8.617296757
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 8.6118695887
MESH:D002292 Carcinoma, Renal Cell zoledronic acid 8.6118507039
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.4912490120
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 8.6016033868
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 8.6017066447 18986760 16280240 16757204
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 8.6018572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 8.6018922899
MESH:D006332 Cardiomegaly Phenylephrine 5.4115728586 17124262 17287366 11179087 16170337 11754973
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.4118850075 18670907 16120746
MESH:D009202 Cardiomyopathies Oleylethanolamide 5.1116269455
MESH:D002312 Cardiomyopathy, Hypertrophic marker/mechanism 17603482 17603483
MESH:D002318 Cardiovascular Diseases Folic Acid 9.3216755160
MESH:D002318 Cardiovascular Diseases Genistein 9.3216332659
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 9.3216936243
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 5.8914694615
MESH:D002386 Cataract Acetaminophen 5.8910977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 15.637505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 15.6320889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 15.6317174075 2727394 7505956 21159647
MESH:D002471 Cell Transformation, Neoplastic Estradiol 15.6318566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 15.6320056578 19524636
MESH:D002659 Child Development Disorders, Pervasive Testosterone 3.3720678186
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 7.3119052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.3116835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 2.6119486331 9022650
MESH:D002971 Cleft Lip Folic Acid 3.5621254359
MESH:D002972 Cleft Palate Folic Acid 7.968946559 21254359
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 7.9612621046 8697196 16354765 15668235 15340226
MESH:D002972 Cleft Palate Urethane 7.9612810352
MESH:D003092 Colitis Selenium 3.1017936198
MESH:D003110 Colonic Neoplasms 17-(allylamino)-17-demethoxygeldanamycin 6.8315993848
MESH:D003110 Colonic Neoplasms Butyrates 6.8315936596
MESH:D003110 Colonic Neoplasms Fluorouracil 6.8317016597 17172411 17725105 16340194 18772588 17287894 15001691 17018589 16510598 17169374
MESH:D003110 Colonic Neoplasms Genistein 6.8317182828
MESH:D015179 Colorectal Neoplasms arsenic trioxide 4.0220501625
MESH:D015179 Colorectal Neoplasms Fluorouracil 4.0216391804 16331619 17255274 15148649 17094418 17695437 14970324 16282729 18448328 18949393 20501625 16303861 18802399 18288408 15289873 18383874 17454858 18509181 16524972 17594712 17401013 17016601
MESH:D015179 Colorectal Neoplasms Folic Acid 4.0216963246 16985020 17087956 17116713 17245555
MESH:D015179 Colorectal Neoplasms Paclitaxel 4.0218802399
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 7.1715095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 7.1714669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.5112609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.1410525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.1420055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Vitamin E 3.1419769572
MESH:D003457 Cryptosporidiosis mangiferin 5.1416547730
MESH:D003490 Cyanosis 2,4-dinitrotoluene 9.1618551238
MESH:D003490 Cyanosis Endosulfan 9.167900959
MESH:D007644 Darier Disease Fluorouracil 4.0816733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.4415213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.1718759878 14531868 11906362 11298694 8970840 8156756 2524372 12868966
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 2.842952479 3621924
MESH:D018500 Diabetes Insipidus, Nephrogenic 17-(allylamino)-17-demethoxygeldanamycin 5.5518854434
MESH:D003921 Diabetes Mellitus, Experimental mangiferin 4.0119028559 12093613
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 14.0820387270
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 14.0816886840
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 14.0816647724
MESH:D003924 Diabetes Mellitus, Type 2 mangiferin 14.089881663 11315760
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 14.0817107852
MESH:D003924 Diabetes Mellitus, Type 2 troglitazone 14.0816023994
MESH:D003925 Diabetic Angiopathies troglitazone 4.9512601628
MESH:D003928 Diabetic Nephropathies Estradiol 7.3119279558
MESH:D003928 Diabetic Nephropathies mangiferin 7.3119960420 19706694
MESH:D003929 Diabetic Neuropathies Progesterone 3.8017187935
MESH:D003967 Diarrhea vorinostat 3.8520479100
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 23.5021346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 23.5018289764 7440962 11289319 16192314 18692083 1440618 9653073 9328219 18648102 9022650 6482804 6679447 8291058
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 23.5021346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 23.5017562736 14725611 19164858 17522070 15968718 16781746 12153990 12958197 10663392 11461765 15619225 11529661 10774834 12705907 16177239 17906064 16081117 19739265 19923254 18071297 2444490 11421492 19420014 12540782 16109766 11287661 19085960 11834606 16485898 11743745 12392966 19416960 16393943 11739529 19370779 14550746 12594235 16227642 18713872 14986274 10915739
MESH:D056486 Drug-Induced Liver Injury Chlorodiphenyl (54% Chlorine) 23.5017851650
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 23.5019107877
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 23.508172417
MESH:D056486 Drug-Induced Liver Injury Selenium 23.5015131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 23.5020420201
MESH:D056486 Drug-Induced Liver Injury troglitazone 23.5014986274
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.3819426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.2211462148
MESH:D004417 Dyspnea cypermethrin 8.7516487989
MESH:D004417 Dyspnea Endosulfan 8.757900959 3388749
MESH:C538011 Eales disease Vitamin E 3.989068938
MESH:D004487 Edema bisindolylmaleimide I 11.418273558
MESH:D004487 Edema Mustard Gas 11.4111428631 11428647 9260866 11402378
MESH:D004487 Edema Tetrachlorodibenzodioxin 11.4112711302 11000095
MESH:D004487 Edema Tetradecanoylphorbol Acetate 11.4115177302 16716910 8273558 9599246 11698051 7812673 8113982
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.1815322242 16714409 18230668
MESH:D004646 Emphysema Endosulfan 5.837900959
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 3.1217692515
MESH:D004714 Endometrial Hyperplasia Genistein 3.8816402032
MESH:D016889 Endometrial Neoplasms Estradiol 9.7011473722 19148513 18566989
MESH:D016889 Endometrial Neoplasms Folic Acid 9.7017301261
MESH:D016889 Endometrial Neoplasms Genistein 9.7011473722
MESH:D004715 Endometriosis Progesterone 6.8716134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 6.879294722 10568697
MESH:D004890 Erythema Mustard Gas 4.459357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.4016302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 17.423581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 17.4220426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 17.4212903497
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 17.4217016578
MESH:D004938 Esophageal Neoplasms docetaxel 17.4216337965
MESH:D004938 Esophageal Neoplasms Fluorouracil 17.4215173087 16337965 16481741 16785472 17638652
MESH:D004938 Esophageal Neoplasms Paclitaxel 17.4216481741
MESH:D017889 Exfoliation Syndrome Folic Acid 4.7816504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.4611564622
MESH:D005221 Fatigue vorinostat 4.8920479100
MESH:D005234 Fatty Liver arsenic trioxide 9.6815073043
MESH:D005234 Fatty Liver Diethylnitrosamine 9.6820387270 21071580
MESH:D005234 Fatty Liver mangiferin 9.6815975614
MESH:D005264 Femoral Fractures zoledronic acid 5.1216234978
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.7711858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.306705139
MESH:D005355 Fibrosis Emodin 6.8219474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 6.8220067830
MESH:D005391 Firesetting Behavior Testosterone 5.137506515
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.5916904648
MESH:D005756 Gastritis Acetaminophen 8.8916983495
MESH:D005756 Gastritis Folic Acid 8.8917171786
MESH:D005833 Genital Neoplasms, Female sodium arsenite 3.9716452187
MESH:D005901 Glaucoma Folic Acid 4.4216504073
MESH:D005909 Glioblastoma Genistein 9.3616598420
MESH:D005909 Glioblastoma Okadaic Acid 9.3617312396
MESH:D005909 Glioblastoma Testosterone 9.3617162496
MESH:D005910 Glioma Fluorouracil 2.5416145905
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.387505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.8710696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 2.8815102660 15162350 18337622
MESH:D034381 Hearing Loss Styrene 4.7917420221
MESH:D006330 Heart Defects, Congenital Folic Acid 8.7916524890 17286298
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 8.7910048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 8.7916080930
MESH:D006331 Heart Diseases mangiferin 10.1412093613
MESH:D006331 Heart Diseases pifithrin 10.1414766674
MESH:D006331 Heart Diseases Urethane 10.1416046796
MESH:D006333 Heart Failure Selenium 2.6117162251
MESH:D006470 Hemorrhage Endosulfan 8.327900959
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 8.3211000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 7.586705139
MESH:D006505 Hepatitis cypermethrin 7.5816487989
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.2216120746 12621046 15340226
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.4016863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 4.3115709030
MESH:D006561 Herpes Simplex mangiferin 4.3110715843
MESH:D006628 Hirsutism Testosterone 4.9317019078
MESH:D006679 HIV Seropositivity Folic Acid 4.7817209195
MESH:D006689 Hodgkin Disease sodium arsenite 2.5712676792
MESH:D019584 Hot Flashes Estradiol 7.6717088409
MESH:D019584 Hot Flashes Vitamin E 7.6714716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.3316959395 18606429 8697196 15340226 16354765
MESH:D006930 Hyperalgesia Acetaminophen 6.1116870215
MESH:D006930 Hyperalgesia zoledronic acid 6.1116769263
MESH:D017588 Hyperandrogenism Testosterone 4.5917019078
MESH:D006934 Hypercalcemia bortezomib 9.3118089816
MESH:D006934 Hypercalcemia zoledronic acid 9.3118089816 19622757
MESH:D020138 Hyperhomocysteinemia Folic Acid 3.8916865747 16395265 16397167 16755160 16433478
MESH:D006946 Hyperinsulinism mangiferin 4.4011315760 9881663
MESH:D006949 Hyperlipidemias mangiferin 4.2015975614
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.2515034207
MESH:D006967 Hypersensitivity mangiferin 4.0816536907
MESH:D006973 Hypertension Phenylephrine 4.2112717712 8949925
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.2118670907 18850075
MESH:D006984 Hypertrophy Phenylephrine 3.9112791704 18502941
MESH:D006996 Hypocalcemia zoledronic acid 5.4712669777
MESH:D007006 Hypogonadism Testosterone 4.0612002444
MESH:D007018 Hypopituitarism Testosterone 5.4817426086
MESH:D007154 Immune System Diseases mangiferin 5.1416076520
MESH:D007174 Impulse Control Disorders Testosterone 5.137506515
MESH:D020244 Infarction, Middle Cerebral Artery pifithrin 9.5719475672
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 9.5715869954
MESH:D007247 Infertility, Female Dieldrin 4.2810630421
MESH:D007248 Infertility, Male Endosulfan 5.649432128 8588293
MESH:D007248 Infertility, Male sodium arsenite 5.6412646999 15346721
MESH:D007249 Inflammation bisindolylmaleimide I 21.248273558
MESH:D007249 Inflammation Diethylnitrosamine 21.2418785209
MESH:D007249 Inflammation Flavonoids 21.2417296493
MESH:D007249 Inflammation mangiferin 21.2415222974
MESH:D007249 Inflammation Mustard Gas 21.249260866 9357497 17524151 8975870 11428620 16001271 11402378 11428647 11428631
MESH:D007249 Inflammation Progesterone 21.2415869954
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 21.2412200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 21.247562506 15177302 11698051 7812673 8273558
MESH:D007251 Influenza, Human Selenium 8.5716624496
MESH:D007251 Influenza, Human Vitamin E 8.5716624496
MESH:D007299 Insect Bites and Stings cypermethrin 5.2615189238
MESH:D007333 Insulin Resistance Estradiol 6.1716393666 16627594
MESH:D007333 Insulin Resistance mangiferin 6.1711315760
MESH:D007511 Ischemia mangiferin 4.5816806951
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.308074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.7016580747
MESH:D007674 Kidney Diseases Acetaminophen 14.2715629191 12587719
MESH:D007674 Kidney Diseases Estradiol 14.2715618244
MESH:D007674 Kidney Diseases mangiferin 14.2712093613
MESH:D007674 Kidney Diseases sodium arsenite 14.2720008137
MESH:D007674 Kidney Diseases Vitamin E 14.2712488133
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 7.9116518626
MESH:D007676 Kidney Failure, Chronic Selenium 7.9116518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 12.9716705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 12.976582329
MESH:D007680 Kidney Neoplasms Estradiol 12.9715610895
MESH:D007680 Kidney Neoplasms Fluorouracil 12.9716985049
MESH:D007859 Learning Disorders Endosulfan 12.518157075
MESH:D007859 Learning Disorders mangiferin 12.5119182383
MESH:D007859 Learning Disorders sevoflurane 12.5119212262
MESH:D044542 LEOPARD Syndrome marker/mechanism 17603483
MESH:D007938 Leukemia 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 8.2612970779
MESH:D007938 Leukemia arsenic trioxide 8.2615070760
MESH:D007938 Leukemia Genistein 8.2618980019 17468513
MESH:D004915 Leukemia, Erythroblastic, Acute troglitazone 5.4216085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 18.0617077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell bortezomib 18.0618089816
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Emodin 18.0617077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell zoledronic acid 18.0618089816
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.6016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 6.9914633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive mangiferin 6.9915498116
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.1319077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.8116467208 19850784 20471514 17050201 16968895
MESH:D015470 Leukemia, Myeloid, Acute bortezomib 3.8120471514
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 2.7219035177 12712474 16891316 16112521 16966277 17712046 19642359 16331271 12679006 12018890 17649720 15336539 11468182 16330433 17107899 15622746 11161223 17869043 15213294 17217047 16823087 15748426 19225113 9834237 19075265
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.6816882451
MESH:D008080 Liposarcoma Paclitaxel 4.1617353645
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.4020032147 19638242 18665156 18407596 18522880
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.7115034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 8.8515571005 17036385 15383259 18371158 17724770 15733078 15369754 15099470 17534399 15842777 14643895 17719030 16169303 15366600 17465448 17881167 15479170 12918455 16009107 15504291 14568256 15067225 17201889 15798949 14726149 15744066 18567088 17196135 15161499 18629640 18239293 14659978 17198567 16042886 18637143 18672772 15577212 17203207 16627068 15081153 18095165 18364076 16544323 15942678 16570917 18237412 17348192 12925901 17432682 15793283 15763062 18210741 16603200 16270385 15339415 15138612 15591649 17640959 15723089 15298665 17666798 14709902 15492853 15864749 15086199
MESH:D008106 Liver Cirrhosis, Experimental Emodin 8.8515288473
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 8.8514659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 8.8517823541
MESH:D008106 Liver Cirrhosis, Experimental inchinko-to 8.8515288473
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 8.8512878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 8.8516169303
MESH:D008107 Liver Diseases Acetaminophen 9.8919460945 11587558 12969438 16611625 19784758 16610002 19014921 12587719
MESH:D008107 Liver Diseases cypermethrin 9.8915991261
MESH:D008107 Liver Diseases Diethylnitrosamine 9.8917034775
MESH:D008107 Liver Diseases Folic Acid 9.8916877991
MESH:D008107 Liver Diseases Lindane 9.891715830
MESH:D017114 Liver Failure, Acute Acetaminophen 7.6116871587 17185352
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 7.6117457977
MESH:D008113 Liver Neoplasms marker/mechanism 19499222
MESH:D008113 Liver Neoplasms arsenic trioxide 23.4814682389
MESH:D008113 Liver Neoplasms Dieldrin 23.489539021 8742319
MESH:D008113 Liver Neoplasms Diethylnitrosamine 23.4812112319 20501860 20492335 19294768 18648771 16942905 10737359 19996281 9163691 20434301 18977376 18978307 20101389 19255062 21278145 19642983 19638242 19551842 19426721 21167192 19499222 2422723 19833225 19090486 20405173 19073162 19254457 2862719 12771043 20118626 20137499 20583210 19812893 15885732 20452335 19850985 15175105 21071580 19256749 19427195 21047994 19690152 18644402 18754104
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 23.4815890375 3113478
MESH:D008113 Liver Neoplasms Fluorouracil 23.4818383874 15113037 16603448 17045692
MESH:D008113 Liver Neoplasms Heptachlor 23.489544696 2422723
MESH:D008113 Liver Neoplasms sodium arsenite 23.4816712894 15276417
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 23.4816984957
MESH:D008113 Liver Neoplasms Urethane 23.4816391232 17559639 17093202
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 13.576587162 598648 1399818 3712494
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 13.5720377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 13.5718544905 19519916 18775883 17174075 19009564 17854601 18079962 2563599 19539802 18282651 16267830 18308698 17942915 9362446 3124819 21159647 18093689 18253720 16842330 18164116 19126423 19004024
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 13.5715603536 1848544 6150874
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.5712151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.8015213294
MESH:D008171 Lung Diseases Mustard Gas 9.4318702808 18161513
MESH:D008171 Lung Diseases sodium arsenite 9.4319095001
MESH:D008171 Lung Diseases Vitamin E 9.4316863852
MESH:D055370 Lung Injury naphthalene 4.346834280
MESH:D008175 Lung Neoplasms marker/mechanism 11884234
MESH:D008175 Lung Neoplasms arsenic trioxide 22.1111798837 19825857
MESH:D008175 Lung Neoplasms Diethylnitrosamine 22.1120970405 6695378 21163286 20512841
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 22.1111884234 19555203 16061637
MESH:D008175 Lung Neoplasms Fluorouracil 22.1115246190
MESH:D008175 Lung Neoplasms mangiferin 22.1118520028 18569708 18816296
MESH:D008175 Lung Neoplasms Mustard Gas 22.118781369 3148597
MESH:D008175 Lung Neoplasms sodium arsenite 22.1115276417 16712894 19931552 17306315 17077188
MESH:D008175 Lung Neoplasms Styrene 22.1112562636
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 22.1119555203 11884234
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 22.1111807781
MESH:D008175 Lung Neoplasms tipifarnib 22.1116885199
MESH:D008175 Lung Neoplasms Urethane 22.1116007126 16391232 17255336 11552296 10997738 15166089 16204055 12957351 10822126 14587096 12765245 11307925 10530776 7750092 12117781 11893704 15902970 16337739 11062179 10779650 17195641 11497255 6695378 16289808 11992545 11246140 11074608 16926031 11323394 11544531 11807781 17093202 16788158 12466968 15136453
MESH:D008175 Lung Neoplasms Vitamin E 22.1111062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.0815086387
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.0917718048
MESH:D008223 Lymphoma bortezomib 4.0416098063
MESH:D016393 Lymphoma, B-Cell bortezomib 4.6616675587
MESH:D017728 Lymphoma, Large-Cell, Anaplastic 17-(allylamino)-17-demethoxygeldanamycin 5.9117157164
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 3.5014749477
MESH:D016410 Lymphoma, T-Cell, Cutaneous vorinostat 4.9920479100
MESH:D015674 Mammary Neoplasms, Animal Styrene 4.7612562636
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 24.9517203775 11807958 11408345 16891317
MESH:D008325 Mammary Neoplasms, Experimental estradiol 3-benzoate 24.9515375486
MESH:D008325 Mammary Neoplasms, Experimental Genistein 24.9514578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 24.9511408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Selenium 24.9515318939
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 24.958985016
MESH:D008325 Mammary Neoplasms, Experimental tipifarnib 24.9516648579
MESH:D008325 Mammary Neoplasms, Experimental zoledronic acid 24.9517312309
MESH:D020149 Manganese Poisoning Estradiol 3.7619453300
MESH:D019767 Maxillofacial Abnormalities Folic Acid 4.9916832597
MESH:D008527 Medulloblastoma bortezomib 3.8919213072
MESH:D008545 Melanoma docetaxel 4.3712417787
MESH:D008545 Melanoma Paclitaxel 4.3712040289 16342250 12025231
MESH:D008545 Melanoma sodium arsenite 4.3719082730 16487513
MESH:D008546 Melanoma, Experimental Acetaminophen 2.8819513568
MESH:D008569 Memory Disorders mangiferin 8.0219182383
MESH:D008569 Memory Disorders sevoflurane 8.0219212262
MESH:D001523 Mental Disorders Phosphates 4.3412686366
MESH:D008654 Mesothelioma Selenium 5.4015107826
MESH:D008654 Mesothelioma zoledronic acid 5.4016675582
MESH:D009062 Mouth Neoplasms Fluorouracil 3.0716757204 18986760
MESH:D009101 Multiple Myeloma arsenic trioxide 13.0419417148 15949261 11468182 14977855 19549372
MESH:D009101 Multiple Myeloma bortezomib 13.0419112201 19372569 19112817
MESH:D009101 Multiple Myeloma Paclitaxel 13.0414749477
MESH:D009101 Multiple Myeloma zoledronic acid 13.0416996129 18089719 19621390
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.9518349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 2.6916105982 16882451
MESH:D009203 Myocardial Infarction Genistein 5.1317141266
MESH:D009203 Myocardial Infarction mangiferin 5.1317052832 16584858 16538859 19172585 16697266
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.4412213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 6.6516810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 6.6517141266
MESH:D009325 Nausea vorinostat 4.8120479100
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.1618551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.2916624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 10.793581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 10.799029167 3581430
MESH:D009362 Neoplasm Metastasis Paclitaxel 10.7915867366
MESH:D009362 Neoplasm Metastasis zoledronic acid 10.7917312309 19139120 15867366
MESH:D009369 Neoplasms Dieldrin 11.498820588
MESH:D009369 Neoplasms Fluorouracil 11.4918600527 16928823 18239605
MESH:D009369 Neoplasms Lindane 11.4912807735 16818664
MESH:D009369 Neoplasms sodium arsenite 11.4911559025
MESH:D009369 Neoplasms Urethane 11.4915625555
MESH:D009374 Neoplasms, Experimental sodium arsenite 7.2020056578
MESH:D009374 Neoplasms, Experimental Urethane 7.2015582191
MESH:D009389 Neovascularization, Pathologic Estradiol 3.0317289903
MESH:D009410 Nerve Degeneration mangiferin 4.0617433543
MESH:D009421 Nervous System Malformations Estradiol 12.4916427766 11399458
MESH:D009421 Nervous System Malformations Genistein 12.4916427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 12.4914600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 13.286679447
MESH:D009436 Neural Tube Defects arsenic trioxide 13.2810525206
MESH:D009436 Neural Tube Defects Folic Acid 13.2817438019
MESH:D009436 Neural Tube Defects sodium arsenite 13.2812854658
MESH:D019636 Neurodegenerative Diseases Acetaminophen 6.2318514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 6.2320387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.4020387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 2.9316436463
MESH:D009503 Neutropenia Folic Acid 7.4316322990
MESH:D009503 Neutropenia Mustard Gas 7.437688884 16761898
MESH:D009634 Noonan Syndrome marker/mechanism 17603482 17603483
MESH:C548083 Noonan Syndrome 5 marker/mechanism
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 11.5712819281 16049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 11.574026338 6482804
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 11.5714694615
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.303988306
MESH:D010014 Osteolysis Paclitaxel 9.9415867366
MESH:D010014 Osteolysis zoledronic acid 9.9415867366
MESH:D010024 Osteoporosis Genistein 5.9819401787
MESH:D010024 Osteoporosis zoledronic acid 5.9817882678
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.4316169203
MESH:D010051 Ovarian Neoplasms 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 22.0216211241
MESH:D010051 Ovarian Neoplasms arsenic trioxide 22.0216624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Estradiol 22.0219401270
MESH:D010051 Ovarian Neoplasms Genistein 22.0219005980
MESH:D010051 Ovarian Neoplasms Paclitaxel 22.0211161223
MESH:D010051 Ovarian Neoplasms Progesterone 22.0216525653 17393432
MESH:D010051 Ovarian Neoplasms sodium arsenite 22.0217306315 15276417
MESH:D010051 Ovarian Neoplasms Urethane 22.0216391232
MESH:D010146 Pain Acetaminophen 5.0616870215
MESH:D010146 Pain zoledronic acid 5.0616475674
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 9.7215580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 9.7216540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 9.7219003803 16500647 16929163 15113037
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 9.7215976015
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 11.667296757
MESH:D010212 Papilloma Hydrogen Peroxide 11.6612065085
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 11.6618922899 18404319 12065085 8330346
MESH:D010235 Paraganglioma arsenic trioxide 3.5019927285
MESH:D010300 Parkinson Disease Dieldrin 5.0311181820 16809432 17291500 11445065 16112328
MESH:D010300 Parkinson Disease mangiferin 5.0317433543
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.5312520081
MESH:D010518 Periodontitis mangiferin 4.8819026997
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 3.756228378
MESH:D010911 Pituitary Neoplasms Urethane 4.7216391232
MESH:D010954 Plasmacytoma Selenium 4.1715087411
MESH:D011041 Poisoning Mustard Gas 3.1515727166
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.8918163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 2.952563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.4911222880 11896295 11399792 11118676
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 8.7420887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Testosterone 8.7420887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 5.0519131511
MESH:D011471 Prostatic Neoplasms Deoxyglucose 5.0518985042
MESH:D011471 Prostatic Neoplasms docetaxel 5.0519103299 16644109 18824434 16520278
MESH:D011471 Prostatic Neoplasms Estradiol 5.0516740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 5.0518626508 19082440
MESH:D011471 Prostatic Neoplasms Genistein 5.0515256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms Heptachlor 5.0512661182
MESH:D011471 Prostatic Neoplasms Lindane 5.0512661182 14688026
MESH:D011471 Prostatic Neoplasms Paclitaxel 5.0516729912 16356831 17172428 17136230
MESH:D011471 Prostatic Neoplasms sodium arsenite 5.0516039940
MESH:D011471 Prostatic Neoplasms Vitamin E 5.0515084515
MESH:D011471 Prostatic Neoplasms vorinostat 5.0517218635
MESH:D011471 Prostatic Neoplasms zoledronic acid 5.0519103299 12438248
MESH:D011537 Pruritus Mustard Gas 3.4018058305
MESH:D011658 Pulmonary Fibrosis Mustard Gas 5.1217266442 17620002 10334151 17894541 17720292
MESH:D011658 Pulmonary Fibrosis troglitazone 5.1218162602
MESH:D011833 Radiation Injuries, Experimental mangiferin 5.6915830843
MESH:D012004 Rectal Neoplasms Fluorouracil 3.4018722050 15538739 18286688 16160472
MESH:D051437 Renal Insufficiency Folic Acid 4.0915728788
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.1618990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 2.833692021
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.5518045962
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 8.3016646077
MESH:D012512 Sarcoma, Ewing's zoledronic acid 8.3016121404
MESH:D012559 Schizophrenia Folic Acid 2.7816641680
MESH:D012640 Seizures 2,4-dinitrotoluene 10.1018551238
MESH:D012640 Seizures Deoxyglucose 10.1017978042
MESH:D012640 Seizures Endosulfan 10.1010698677 7539098
MESH:D012640 Seizures Lindane 10.107539098 12842176 15475178
MESH:D012735 Sexual Dysfunction, Physiological Testosterone 5.4816631401
MESH:D012772 Shock, Septic lipoteichoic acid 9.3419573522
MESH:D012772 Shock, Septic mangiferin 9.3415177305
MESH:D012852 Sinusitis Phenylephrine 4.007327846
MESH:D012871 Skin Diseases Folic Acid 6.6118709164
MESH:D012871 Skin Diseases Mustard Gas 6.6115451306 12880345 16961503
MESH:D012871 Skin Diseases Vitamin E 6.6118709164
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 17.4312065085
MESH:D012878 Skin Neoplasms Okadaic Acid 17.4312628509
MESH:D012878 Skin Neoplasms sodium arsenite 17.4319524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 17.4316192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 17.438330346 12065085 18404319 11807781 8985016
MESH:D012878 Skin Neoplasms Urethane 17.4311807781
MESH:D013118 Spinal Cord Diseases Folic Acid 4.7816361298
MESH:D013119 Spinal Cord Injuries Progesterone 3.5815862959 16503802
MESH:D016135 Spinal Dysraphism sodium arsenite 3.2312854658
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.5512587719
MESH:D013274 Stomach Neoplasms arsenic trioxide 10.5817007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 10.5818456281
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 10.5816033868
MESH:D013274 Stomach Neoplasms docetaxel 10.5816557585
MESH:D013274 Stomach Neoplasms Fluorouracil 10.5816951190 16424979 18567086 17172411 19015929 18396642 17498489 19084572 17522103 15786421
MESH:D013274 Stomach Neoplasms Folic Acid 10.5817171786
MESH:D013274 Stomach Neoplasms Paclitaxel 10.5818506536 18396642
MESH:D013274 Stomach Neoplasms troglitazone 10.5815930296
MESH:D013276 Stomach Ulcer mangiferin 3.6717918041
MESH:D020521 Stroke Folic Acid 6.9916517955
MESH:D020521 Stroke Vitamin E 6.9916517955
MESH:D013345 Subarachnoid Hemorrhage pifithrin 5.3418364113
MESH:D024801 Tauopathies Paclitaxel 4.1116930453
MESH:D013742 Tetanus Propofol 5.712903605
MESH:D013921 Thrombocytopenia vorinostat 4.3520479100
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.1812697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 16.647505956 6582329 6587162 3712494 1399818
MESH:D013964 Thyroid Neoplasms 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine 16.6416940797
MESH:D013964 Thyroid Neoplasms arsenic trioxide 16.6419014326
MESH:D013964 Thyroid Neoplasms Butyrates 16.6417967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 16.647505956
MESH:D013978 Tibial Fractures Estradiol 3.9619048282
MESH:D014062 Tongue Neoplasms Fluorouracil 3.3716280240
MESH:D016171 Torsades de Pointes arsenic trioxide 3.2615213294
MESH:D014235 Trichinellosis mangiferin 5.3414669257
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 9.1116049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 9.118074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 9.1112845720 20435036 12973940 11780464
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 9.1116452187 16712894 11723127 17306315
MESH:D014570 Urologic Diseases cypermethrin 5.1516487989
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.6110091137
MESH:D014581 Urticaria Acetaminophen 2.3310982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 7.4216803524
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 7.4211813266
MESH:D014652 Vascular Diseases sodium arsenite 3.7217056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.8712125929
MESH:D019043 Vascular Neoplasms Urethane 5.1910620525
MESH:D020301 Vasospasm, Intracranial pifithrin 4.9118364113
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.5315886252
Pathway ID Pathway Name
KEGG:05221 Acute myeloid leukemia
REACT:18266 Axon guidance
KEGG:04662 B cell receptor signaling pathway
KEGG:05219 Bladder cancer
KEGG:04062 Chemokine signaling pathway
KEGG:05220 Chronic myeloid leukemia
KEGG:05210 Colorectal cancer
KEGG:04320 Dorso-ventral axis formation
KEGG:05213 Endometrial cancer
KEGG:04012 ErbB signaling pathway
KEGG:04664 Fc epsilon RI signaling pathway
KEGG:04666 Fc gamma R-mediated phagocytosis
KEGG:04510 Focal adhesion
KEGG:04540 Gap junction
KEGG:05214 Glioma
KEGG:04912 GnRH signaling pathway
REACT:604 Hemostasis
KEGG:05160 Hepatitis C
KEGG:04910 Insulin signaling pathway
KEGG:04730 Long-term depression
KEGG:04720 Long-term potentiation
KEGG:04010 MAPK signaling pathway
KEGG:04013 MAPK signaling pathway - fly
KEGG:04916 Melanogenesis
KEGG:05218 Melanoma
KEGG:04150 mTOR signaling pathway
KEGG:04650 Natural killer cell mediated cytotoxicity
KEGG:04722 Neurotrophin signaling pathway
KEGG:05223 Non-small cell lung cancer
KEGG:05212 Pancreatic cancer
KEGG:05200 Pathways in cancer
KEGG:04914 Progesterone-mediated oocyte maturation
KEGG:05215 Prostate cancer
KEGG:04810 Regulation of actin cytoskeleton
KEGG:05211 Renal cell carcinoma
REACT:9417 Signaling by EGFR
REACT:498 Signaling by Insulin receptor
REACT:16888 Signaling by PDGF
REACT:6900 Signaling in Immune system
REACT:11061 Signalling by NGF
REACT:13685 Synaptic Transmission
KEGG:04660 T cell receptor signaling pathway
KEGG:05152 Tuberculosis
KEGG:04270 Vascular smooth muscle contraction
KEGG:04370 VEGF signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA34183
    • No data
    Releated disease ID Related disease Name
    PA444985Multiple Myeloma
    PA445062Neoplasms
    PA443633Cardiomyopathy, Hypertrophic
    PA445123Noonan Syndrome
    PA445103Neurofibromatosis 1
    Releated drug ID Related drug Name
    PA451578tacrolimus
    PA448497aspirin
    PA164743471adenosine triphosphate
    PA151917011valinomycin
    PA449780glutathione
    PA450631nifedipine
    PA450191lecithin
    PA448948chloroquine
    PA10804imatinib
    PA449167cyclosporine
    PA7000sorafenib
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00398 antagonist Sorafenib Antineoplastic Agents;Protein Kinase Inhibitors;Anticancer Agents
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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