AutismKB 2.0

Annotation Detail for RALA


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Basic Information Top
Gene Symbol:RALA ( MGC48949,RAL )
Gene Full Name: v-ral simian leukemia viral oncogene homolog A (ras related)
Band: 7p14.1
Quick LinksEntrez ID:5898; OMIM: 179550; Uniprot ID:RALA_HUMAN; ENSEMBL ID: ENSG00000006451; HGNC ID: 9839
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05212Pancreatic cancer
hsa05200Pathways in cancer
Pathway IDPathway Name
Signalling by NGF
Pathway IDPathway Name
200113ErbB1 downstream signaling
200046Arf6 trafficking events
Pathway IDPathway Name
P04393Ras Pathway
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of RALA mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of RALA mRNAaffects expression 21346803
C029955 2-nitrotoluene 2-nitrotoluene results in decreased expression of RALA mRNAdecreases expression 16460773
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of RALA mRNAdecreases expression 18648102
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RALA mRNAaffects expression 16483693
D000728 Androgens Androgens affects the activity of RALA proteinaffects activity 16964283
D000728 Androgens Androgens affects the reaction [RALA protein affects the expression of VEGFC mRNA]affects expression|affects reaction 16964283
D000728 Androgens Androgens affects the reaction [Reactive Oxygen Species results in increased activity of RALA protein]affects reaction|increases activity 16964283
C006632 arsenic trioxide arsenic trioxide results in increased expression of RALA mRNAincreases expression 20458559
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of RALA mRNAdecreases expression 20064835
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RALA mRNAdecreases expression 19150397
C099813 bromochloroacetic acid bromochloroacetic acid results in decreased expression of RALA mRNAdecreases expression 16460773
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of RALA mRNAincreases expression 15336504
D002713 Chlorine [Ozone co-treated with Chlorine] affects the expression of RALA mRNAaffects cotreatment|affects expression 18636392
D016572 Cyclosporine Cyclosporine results in increased expression of RALA mRNAincreases expression 20106945
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RALA mRNAaffects cotreatment|increases expression 17942748
D006220 Haloperidol Haloperidol results in increased expression of RALA mRNAincreases expression 15860345
D007657 Ketone Bodies Ketone Bodies results in decreased expression of RALA mRNAdecreases expression 15469884
D001556 Lindane Lindane results in increased expression of RALA mRNAincreases expression 17785943
D010126 Ozone [Ozone co-treated with Chlorine] affects the expression of RALA mRNAaffects cotreatment|affects expression 18636392
D010126 Ozone Ozone results in decreased expression of RALA mRNAdecreases expression 16330353
D011794 Quercetin Quercetin results in decreased expression of RALA mRNAdecreases expression 15309432
D017382 Reactive Oxygen Species Androgens affects the reaction [Reactive Oxygen Species results in increased activity of RALA protein]affects reaction|increases activity 16964283
D017382 Reactive Oxygen Species Reactive Oxygen Species results in increased activity of RALA proteinincreases activity 16964283
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RALA mRNAaffects cotreatment|increases expression 17942748
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7414514962 11752688 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.4518287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8417505938
MESH:D055371 Acute Lung Injury Chlorine 4.2220601635
MESH:D000230 Adenocarcinoma arsenic trioxide 6.8619825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 6.8620127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.8614692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 6.383712494
MESH:D000236 Adenoma Benzo(a)pyrene 6.386695378
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.2716835633
MESH:D000382 Agricultural Workers' Diseases Lindane 4.2612661182
MESH:D000544 Alzheimer Disease Androgens 4.6817917157 17182789
MESH:D000544 Alzheimer Disease Ozone 4.6815513908
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8511748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.1417084956
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.9619183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.3611256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6015885639
MESH:D001172 Arthritis, Rheumatoid Ozone 2.5315570426
MESH:D001249 Asthma Ozone 2.6017854713 16373670
MESH:D001260 Ataxia Telangiectasia Quercetin 4.8715336622
MESH:D001321 Autistic Disorder Haloperidol 2.7519368416 18080171
MESH:D001327 Autoimmune Diseases Quercetin 4.3019761891
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.9111289319 1440618
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 8.6216206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.6212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6915746008
MESH:D001943 Breast Neoplasms Androgens 2.3417018787
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.3417474063 20146248
MESH:D001943 Breast Neoplasms Lindane 2.3414688026
MESH:D001943 Breast Neoplasms Quercetin 2.3418628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.3420435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.5918315731 17626835 18417511 14754758 16777450 19059883 15516495
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.2211589617
MESH:D002100 Cachexia Ozone 4.6316183385
MESH:D002105 Cadmium Poisoning Quercetin 5.4416962696
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7116835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 8.6916705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 8.6916705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 8.693581430 7296757
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 8.6916217749 15553829 14691202 15073043 11135700
MESH:D006528 Carcinoma, Hepatocellular Quercetin 8.6919519916 12508355
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.8517234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7719014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.627296757
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.0212490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.0220419170
MESH:D006332 Cardiomegaly Quercetin 6.6019794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.6018670907 18850075 16120746
MESH:D002375 Catalepsy Haloperidol 4.801977408 15215559
MESH:D002430 Cecal Neoplasms 2-nitrotoluene 5.5814688030
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 15.386135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 15.387505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 15.3820889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 15.3812371664
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0716835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 12.9119486331 9022650
MESH:D002779 Cholestasis Cyclosporine 12.9119486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.9115861022 17681005 17110522 11677210 16105132 17333356 16919318
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0616354765 15340226 8697196 15668235 12621046
MESH:D003110 Colonic Neoplasms Quercetin 2.4019056647 16640504 17191121 19440933 11134977 17148506 15741050
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.5920501625
MESH:D015179 Colorectal Neoplasms Quercetin 2.5918095365 18852136
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9614669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 4.0812609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.8610525206
MESH:D019465 Craniofacial Abnormalities Reactive Oxygen Species 3.8615736158
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.8615322242 20055451 10048152
MESH:D016638 Critical Illness Androgens 5.9516670151
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.5318551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.5318551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 10.5715213294
MESH:D016757 Death, Sudden, Cardiac Haloperidol 10.5720210726
MESH:D003704 Dementia Haloperidol 4.4811575062
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.7012868966 8970840 18759878 11906362 2524372 11298694 14531868 8156756
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.393621924 2952479
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.6419496084
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6417107852
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 8.6921346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 8.6918551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 8.6916192314 9022650 7440962 8291058 18289764 1440618 18692083 6679447 9328219 6482804 11289319 18648102 9653073
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 8.6920420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6811462148
MESH:D004417 Dyspnea Chlorine 4.5220016425
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.2811000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8018230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.0812538720
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.929294722 10568697
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 10.143581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.1420426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 10.1412903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 10.1416530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9311564622
MESH:D005234 Fatty Liver arsenic trioxide 12.4815073043
MESH:D005234 Fatty Liver Cyclosporine 12.4819224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 12.4815345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3511858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.916705139
MESH:D005355 Fibrosis Cyclosporine 14.1412639820 12168785
MESH:D005355 Fibrosis Quercetin 14.1419474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.1420067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1516904648
MESH:D005739 Gas Poisoning Chlorine 4.9020016425
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.118708960
MESH:D005909 Glioblastoma Quercetin 3.3219804834
MESH:D005910 Glioma Quercetin 3.0117643826
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.937505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4910696789
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.2620471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.2611294989 10048152
MESH:D006394 Hemangiosarcoma 2-nitrotoluene 4.9813678655
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3115720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2311000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.416705139
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.7815340226 12621046 16120746
MESH:D006628 Hirsutism Androgens 5.9717019078 16914592
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.948697196 18606429 15340226 16959395 16354765
MESH:D017588 Hyperandrogenism Androgens 5.6317019078
MESH:D006943 Hyperglycemia Quercetin 3.9311834736 18262572
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.8315034207
MESH:D006973 Hypertension Cyclosporine 8.3410903974
MESH:D006973 Hypertension Quercetin 8.3418356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.3418850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7016569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3612013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4117937319
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.8012200463 12878042
MESH:D007251 Influenza, Human Quercetin 4.4016624496
MESH:D002532 Intracranial Aneurysm Reactive Oxygen Species 4.8519381132
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.918074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2316580747
MESH:D007627 Keloid Quercetin 4.8517086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3415604871
MESH:D007674 Kidney Diseases Cyclosporine 5.928314463 10903974 18776723
MESH:D007674 Kidney Diseases Quercetin 5.9216962696
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 16.9916705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 16.9916705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 16.996582329
MESH:D007680 Kidney Neoplasms Cyclosporine 16.9912371664
MESH:D007938 Leukemia arsenic trioxide 6.3015070760
MESH:D007938 Leukemia Quercetin 6.3017468513
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.6917077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.2016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.6619077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1216968895 17050201 19850784 20471514 16467208
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.1415622746 19035177 15748426 12712474 16330433 17107899 15213294 17217047 16331271 16112521 17869043 19642359 11161223 12018890 12679006 11468182 16966277 17712046 19225113 9834237 15336539 17649720 19075265 16823087 16891316
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.2416882451
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.1315034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 2.4112741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.4112878042
MESH:D008107 Liver Diseases Lindane 3.071715830
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 13.807678174
MESH:D008113 Liver Neoplasms arsenic trioxide 13.8014682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 13.8021137059 20195826
MESH:D008113 Liver Neoplasms Quercetin 13.8018980244
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 13.8016984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 17.922876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 17.921399818 3712494 598648 6587162
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 17.9220377131
MESH:D008114 Liver Neoplasms, Experimental Quercetin 17.9219519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 17.9212151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.2615213294
MESH:D008171 Lung Diseases Ozone 3.3019066396 8266340
MESH:D055370 Lung Injury Ozone 3.7420417186
MESH:D008175 Lung Neoplasms arsenic trioxide 6.4519825857 11798837
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 6.4520464547 20869020 17053015 20135361 18520028 6695378 18569708 20064080 18816296
MESH:D008175 Lung Neoplasms Ozone 6.458597069 7614698
MESH:D008175 Lung Neoplasms Quercetin 6.4516280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.4511884234 19555203
MESH:D008545 Melanoma Reactive Oxygen Species 3.1617992120
MESH:D001523 Mental Disorders Haloperidol 3.9116856516
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6816801185
MESH:D008679 Metaplasia Ozone 5.0010496685
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.1016381670
MESH:D009101 Multiple Myeloma arsenic trioxide 3.0314977855 11468182 15949261 19549372 19417148
MESH:D019042 Muscle Neoplasms 2-nitrotoluene 6.5813678655
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5718349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.0816105982 16882451
MESH:D009203 Myocardial Infarction Quercetin 2.9519595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9312213967
MESH:D015428 Myocardial Reperfusion Injury Quercetin 3.7119207477
MESH:D009336 Necrosis 2,4-dinitrotoluene 9.9818551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 9.987678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.8516624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.433581430
MESH:D009369 Neoplasms Benzo(a)pyrene 8.1211141357
MESH:D009369 Neoplasms Lindane 8.1212807735 16818664
MESH:D009369 Neoplasms Quercetin 8.1215185748
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1918481113 19348381
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.1114600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.016679447
MESH:D009436 Neural Tube Defects arsenic trioxide 7.0110525206
MESH:D020078 Neurogenic Inflammation Quercetin 4.2617929310
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 14.5012819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 14.5016049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 14.506482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.913988306
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.1119495926
MESH:D010051 Ovarian Neoplasms arsenic trioxide 4.9016624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms Quercetin 4.9019005980
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.6115580305
MESH:D010190 Pancreatic Neoplasms Quercetin 8.6116965848
MESH:D010190 Pancreatic Neoplasms Reactive Oxygen Species 8.6115580305
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5811578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.387296757
MESH:D010235 Paraganglioma arsenic trioxide 4.0619927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1412520081
MESH:D010538 Peritonitis Ozone 4.0216369182
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.366228378
MESH:D011014 Pneumonia Ozone 4.2918929643 18007984 18381685
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4518163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.7912371664
MESH:D011230 Precancerous Conditions Quercetin 8.7919056647
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.0811896295 11222880 11399792 11118676
MESH:D011471 Prostatic Neoplasms Androgens 1.9117909013 16998812 15389811
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.9119131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.9117292933
MESH:D011471 Prostatic Neoplasms Lindane 1.9114688026 12661182
MESH:D011471 Prostatic Neoplasms Quercetin 1.9114715546 17292933
MESH:D011537 Pruritus Ethinyl Estradiol 3.2016919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.1916882103
MESH:D011595 Psychomotor Agitation Haloperidol 4.8511575062
MESH:D011618 Psychotic Disorders Haloperidol 4.1711575062
MESH:D012120 Respiration Disorders Chlorine 5.1118579056
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7318990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.293692021
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.8516646077
MESH:D012554 Schistosomiasis japonica Quercetin 5.4416862918
MESH:D012559 Schizophrenia Haloperidol 2.791830565 20107430 19369910 18513383
MESH:D012640 Seizures 2,4-dinitrotoluene 9.5018551238
MESH:D012640 Seizures 2,6-dinitrotoluene 9.5018551238
MESH:D012640 Seizures Lindane 9.507539098 12842176 15475178
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 9.1019755658 10029692
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 9.108532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.1016192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.8416709447
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.3417007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.342093021 20155912
MESH:D017180 Tachycardia, Ventricular Haloperidol 4.6020210726
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0615669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8012697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 6.886582329 1399818 7505956 6587162 3712494
MESH:D013964 Thyroid Neoplasms arsenic trioxide 6.8819014326
MESH:D016171 Torsades de Pointes arsenic trioxide 3.8515213294
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 19.3316049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 19.3316049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 19.338074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 19.3312845720 12973940 20435036 11780464
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 19.3317053015
MESH:D001749 Urinary Bladder Neoplasms Quercetin 19.3316720314
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.6310091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.6310091137
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1914692618
MESH:D014605 Uveitis Cyclosporine 3.881336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4912125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4414671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1415886252
MESH:D014985 Xerophthalmia Cyclosporine 4.3417120751
Pathway ID Pathway Name
KEGG:05212 Pancreatic cancer
KEGG:05200 Pathways in cancer
REACT:11061 Signalling by NGF
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA34197
    • No data
    No data
    Releated drug ID Related drug Name
    PA448976choline
    PA450191lecithin
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB04315 - Guanosine-5'-Diphosphate
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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