AutismKB 2.0

Annotation Detail for RARA


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Basic Information Top
Gene Symbol:RARA ( NR1B1,RAR )
Gene Full Name: retinoic acid receptor, alpha
Band: 17q21.2
Quick LinksEntrez ID:5914; OMIM: 180240; Uniprot ID:RARA_HUMAN; ENSEMBL ID: ENSG00000131759; HGNC ID: 9864
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05221Acute myeloid leukemia
hsa05200Pathways in cancer
Pathway IDPathway Name
Gene Expression
Pathway IDPathway Name
200142Retinoic acid receptors-mediated signaling
200112RXR and RAR heterodimerization with other nuclear receptor
Pathway IDPathway Name
P04396Vitamin D metabolism and pathway
No data
Related Diseases/Disorders Top
Desease IDDesease Name
Cancers of haematopoietic and lymphoid tissues
Cancers
H00003Acute myeloid leukemia (AML)
Desease IDDesease Name
1781Rheumatoid arthritis
1831Prostate cancer
1856Obesity
1944Breast cancer
1993Esophagus cancer
2011Leukoencephalopathy
2051Leukemia
Desease Name
DEVELOPMENTAL
cleft lip with cleft palate cleft lip without cleft palate
No data
Desease Name
Leukemia, acute promyelocytic
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C496751 4-(1H-imidazol-1-yl)retinoic acid 4-(1H-imidazol-1-yl)retinoic acid binds to RARA proteinaffects binding 17387344
C038864 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid binds to and results in increased activity of RARA proteinaffects binding|increases activity 15589975
16178010
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of RARA mRNAdecreases expression 18648102
C064545 4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid 4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid binds to RARA proteinaffects binding 15589975
C002202 4-oxoretinoic acid 4-oxoretinoic acid results in increased expression of RARA mRNAincreases expression 17034753
C041819 4-oxoretinol 4-oxoretinol results in increased expression of RARA mRNAincreases expression 17034753
C096920 AGN 193109 AGN 193109 binds to and results in decreased activity of RARA proteinaffects binding|decreases activity 15589975
C096920 AGN 193109 AGN 193109 binds to and results in decreased activity of RARA proteinaffects binding|decreases activity 16982809
C121616 AGN 194310 AGN 194310 binds to and results in decreased activity of RARA proteinaffects binding|decreases activity 16178010
C492393 AGN 195183 AGN 195183 binds to and results in increased activity of RARA proteinaffects binding|increases activity 16178010
C492393 AGN 195183 AGN 195183 binds to and results in increased activity of RARA proteinaffects binding|increases activity 17318068
D019386 Alendronate Alendronate affects the expression of RARA mRNAaffects expression 16079270
C103303 alitretinoin alitretinoin promotes the reaction [RARA protein binds to PRAME protein]affects binding|increases reaction 16179254
C103303 alitretinoin alitretinoin results in decreased expression of RARA proteindecreases expression 15375546
C103303 alitretinoin alitretinoin results in increased expression of RARA mRNAincreases expression 11139446
17034753
C103303 alitretinoin RARA protein promotes the reaction [alitretinoin results in increased expression of ABCC6 mRNA]increases expression|increases reaction 17045963
C103303 alitretinoin alitretinoin results in increased expression of RARA mRNAincreases expression 8892963
C103303 alitretinoin alitretinoin results in increased expression of RARA proteinincreases expression 16043492
C103303 alitretinoin [Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein]affects cotreatment|increases activity|increases reaction 15773917
C103303 alitretinoin CAMK4 protein promotes the reaction [alitretinoin results in increased activity of RARA protein]increases activity|increases reaction 15773917
C103303 alitretinoin Dizocilpine Maleate inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein]]affects cotreatment|decreases reaction|increases activity|increases reaction 15773917
C103303 alitretinoin KN 62 inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein]]affects cotreatment|decreases reaction|increases activity|increases reaction 15773917
C103303 alitretinoin Okadaic Acid promotes the reaction [alitretinoin results in increased activity of RARA protein]increases activity|increases reaction 15773917
C103303 alitretinoin STO 609 inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein]]affects cotreatment|decreases reaction|increases activity|increases reaction 15773917
C103303 alitretinoin trichostatin A promotes the reaction [alitretinoin results in increased activity of RARA protein]increases activity|increases reaction 15773917
C068073 Am 580 Am 580 binds to and results in increased activity of RARA proteinaffects binding|increases activity 10779427
16178010
C068073 Am 580 Am 580 results in increased expression of RARA proteinincreases expression 16636311
C068073 Am 580 Am 580 binds to and affects the activity of RARA proteinaffects activity|affects binding 16982809
C068073 Am 580 Am 580 binds to and results in increased activity of RARA proteinaffects binding|increases activity 15855632
17392484
C068073 Am 580 Am 580 results in increased activity of RARA proteinincreases activity 17460283
C061133 Am 80 Am 80 binds to and affects the activity of RARA proteinaffects activity|affects binding 16982755
C061133 Am 80 Am 80 binds to and results in increased activity of RARA proteinaffects binding|increases activity 16819260
D015761 4-Aminopyridine [Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein]affects cotreatment|increases activity|increases reaction 15773917
D015761 4-Aminopyridine Dizocilpine Maleate inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein]]affects cotreatment|decreases reaction|increases activity|increases reaction 15773917
D015761 4-Aminopyridine KN 62 inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein]]affects cotreatment|decreases reaction|increases activity|increases reaction 15773917
D015761 4-Aminopyridine STO 609 inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein]]affects cotreatment|decreases reaction|increases activity|increases reaction 15773917
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RARA mRNAaffects expression 16483693
D000966 Antimony Potassium Tartrate Antimony Potassium Tartrate results in increased degradation of RARA protein mutant formincreases degradation 9834237
C037554 antimony trioxide antimony trioxide results in increased degradation of RARA protein mutant formincreases degradation 9834237
C004984 apocarotenal apocarotenal results in decreased expression of RARA mRNAdecreases expression 17034753
C006632 arsenic trioxide arsenic trioxide promotes the reaction [puerarin results in decreased expression of RARA mRNA alternative form]decreases expression|increases reaction 20416161
C006632 arsenic trioxide arsenic trioxide results in increased degradation of RARA protein mutant formincreases degradation 16891316
15748426
9834237
C006632 arsenic trioxide cobaltous chloride promotes the reaction [arsenic trioxide results in increased degradation of RARA protein mutant form]increases degradation|increases reaction 16330433
C006632 arsenic trioxide [Tretinoin co-treated with arsenic trioxide] results in decreased expression of RARA mRNA alternative formaffects cotreatment|decreases expression 19225113
C006632 arsenic trioxide arsenic trioxide results in increased degradation of and results in decreased expression of RARA proteindecreases expression|increases degradation 15688020
C045816 arsenic trisulfide arsenic trisulfide results in increased degradation of and results in decreased expression of RARA proteindecreases expression|increases degradation 12513809
C045816 arsenic trisulfide arsenic trisulfide results in increased degradation of and results in decreased expression of RARA protein mutant formdecreases expression|increases degradation 12513809
D001564 Benzo(a)pyrene Benzo(a)pyrene affects the activity of RARA proteinaffects activity 20624995
D019207 beta Carotene beta Carotene results in decreased expression of RARA mRNAdecreases expression 17034753
D001640 Bicuculline [Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein]affects cotreatment|increases activity|increases reaction 15773917
D001640 Bicuculline Dizocilpine Maleate inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein]]affects cotreatment|decreases reaction|increases activity|increases reaction 15773917
D001640 Bicuculline KN 62 inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein]]affects cotreatment|decreases reaction|increases activity|increases reaction 15773917
D001640 Bicuculline STO 609 inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein]]affects cotreatment|decreases reaction|increases activity|increases reaction 15773917
C006780 bisphenol A bisphenol A results in decreased expression of RARA mRNAdecreases expression 14967906
C006780 bisphenol A bisphenol A results in increased expression of RARA mRNAincreases expression 15738621
14967906
D002087 Butyrates [Tretinoin co-treated with Butyrates] results in increased cleavage of RARA protein mutant formaffects cotreatment|increases cleavage 12130515
C055494 caffeic acid phenethyl ester caffeic acid phenethyl ester promotes the reaction [Tretinoin results in increased activity of RARA protein]increases activity|increases reaction 16766008
C055494 caffeic acid phenethyl ester caffeic acid phenethyl ester results in increased activity of RARA proteinincreases activity 16766008
C055494 caffeic acid phenethyl ester caffeic acid phenethyl ester results in increased expression of RARA mRNAincreases expression 16766008
C055494 caffeic acid phenethyl ester caffeic acid phenethyl ester results in increased expression of RARA proteinincreases expression 16766008
C055494 caffeic acid phenethyl ester [Tretinoin co-treated with caffeic acid phenethyl ester] results in increased expression of RARA mRNAaffects cotreatment|increases expression 16766008
C055494 caffeic acid phenethyl ester [Tretinoin co-treated with caffeic acid phenethyl ester] results in increased expression of RARA proteinaffects cotreatment|increases expression 16766008
D002746 Chlorpromazine Chlorpromazine results in decreased expression of RARA mRNAdecreases expression 18246545
C018021 cobaltous chloride cobaltous chloride promotes the reaction [arsenic trioxide results in increased degradation of RARA protein mutant form]increases degradation|increases reaction 16330433
D003474 Curcumin Curcumin inhibits the reaction [TGFB1 protein results in increased expression of RARA mRNA]decreases reaction|increases expression 8940178
C014347 decitabine [decitabine co-treated with Tretinoin] results in increased expression of RARA mRNAaffects cotreatment|increases expression 19524134
C014347 decitabine decitabine promotes the reaction [vorinostat results in increased expression of RARA mRNA]increases expression|increases reaction 17417771
D003840 Deoxycholic Acid [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of RARA mRNAaffects cotreatment|increases expression 16556975
D003907 Dexamethasone Dexamethasone results in increased expression of RARA mRNAincreases expression 19022236
D002945 Cisplatin Cisplatin results in increased expression of RARA mRNAincreases expression 18172885
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of RARA mRNAaffects cotreatment|decreases expression 18544905
D004052 Diethylnitrosamine [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of RARA mRNAaffects cotreatment|decreases expression 18253720
D016291 Dizocilpine Maleate Dizocilpine Maleate inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein]]affects cotreatment|decreases reaction|increases activity|increases reaction 15773917
C045651 epigallocatechin gallate epigallocatechin gallate results in increased expression of RARA mRNAincreases expression 12628509
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of RARA mRNAaffects cotreatment|decreases expression 19619570
D004958 Estradiol Estradiol results in decreased expression of RARA mRNAdecreases expression 19619570
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of RARA mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of RARA mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RARA mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of RARA mRNAaffects expression 16079270
D011345 Fenofibrate [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of RARA mRNAaffects cotreatment|decreases expression 18253720
D005839 Gentamicins Gentamicins results in increased expression of RARA mRNAincreases expression 18172885
C030691 gluconic acid [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of RARA mRNAaffects cotreatment|increases expression 16556975
D006118 Griseofulvin Griseofulvin results in increased expression of RARA mRNAincreases expression 9548566
D019307 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [TGFB1 protein results in increased expression of RARA mRNA]decreases reaction|increases expression 8940178
C014026 hexamethylene bisacetamide [Tretinoin co-treated with hexamethylene bisacetamide] results in increased cleavage of RARA protein mutant formaffects cotreatment|increases cleavage 12130515
D017313 Fenretinide Fenretinide results in decreased expression of RARA proteindecreases expression 15375546
D017313 Fenretinide Fenretinide results in increased expression of RARA mRNAincreases expression 15735044
D006918 Hydroxyurea Hydroxyurea results in increased mutagenesis of RARA geneincreases mutagenesis 16868089
C063302 KN 62 KN 62 inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein]]affects cotreatment|decreases reaction|increases activity|increases reaction 15773917
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of RARA mRNAaffects cotreatment|decreases expression 18544905
C008281 limonene limonene results in decreased expression of RARA mRNAdecreases expression 12815608
D008070 Lipopolysaccharides Lipopolysaccharides promotes the reaction [Tretinoin results in increased expression of RARA mRNA]increases expression|increases reaction 17216566
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of RARA proteindecreases expression 16002565
D008550 Melatonin Melatonin promotes the reaction [Tretinoin results in increased activity of RARA protein]increases activity|increases reaction 15813899
D008770 Methylnitrosourea Methylnitrosourea results in increased mutagenesis of RARA geneincreases mutagenesis 16868089
C007350 nitrofen nitrofen results in increased expression of RARA mRNAincreases expression 17270546
C508934 N-retinoylglucosamine N-retinoylglucosamine results in increased expression of RARA mRNAincreases expression 16280019
D019319 Okadaic Acid Okadaic Acid promotes the reaction [alitretinoin results in increased activity of RARA protein]increases activity|increases reaction 15773917
D010672 Phenytoin Phenytoin results in decreased expression of RARA mRNAdecreases expression 9118846
D010672 Phenytoin Phenytoin results in increased expression of RARA mRNAincreases expression 9988880
D011078 Polychlorinated Biphenyls Polychlorinated Biphenyls results in increased expression of RARA proteinincreases expression 17287035
C033607 puerarin arsenic trioxide promotes the reaction [puerarin results in decreased expression of RARA mRNA alternative form]decreases expression|increases reaction 20416161
C033607 puerarin puerarin results in decreased expression of RARA mRNA alternative formdecreases expression 20416161
D020849 Raloxifene Raloxifene affects the expression of RARA mRNAaffects expression 16079270
D015474 Isotretinoin Isotretinoin results in increased expression of RARA mRNAincreases expression 9262057
D012176 Retinoids RARA protein promotes the reaction [Retinoids results in increased expression of FOXK2 mRNA]increases expression|increases reaction 12075115
D012176 Retinoids RARA protein promotes the reaction [Retinoids results in increased expression of TGM2 mRNA]increases expression|increases reaction 12075115
D012176 Retinoids Retinoids binds to and results in increased activity of RARA proteinaffects binding|increases activity 12075115
C014794 retinol palmitate retinol palmitate promotes the reaction [RARA protein binds to MMP9 protein]affects binding|increases reaction 17164434
C084904 Ro 41-5253 Ro 41-5253 binds to and results in decreased activity of RARA proteinaffects binding|decreases activity 7556191
10779427
C084904 Ro 41-5253 Ro 41-5253 inhibits the reaction [Tretinoin results in increased expression of RARA mRNA]decreases reaction|increases expression 17216566
C084904 Ro 41-5253 Ro 41-5253 binds to and results in decreased activity of RARA proteinaffects binding|decreases activity 8838863
C084904 Ro 41-5253 Ro 41-5253 binds to and results in decreased activity of RARA proteinaffects binding|decreases activity 16085646
16872382
D012967 Sodium Dodecyl Sulfate Sodium Dodecyl Sulfate results in decreased expression of RARA mRNAdecreases expression 12815608
C458525 STO 609 STO 609 inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein]]affects cotreatment|decreases reaction|increases activity|increases reaction 15773917
D014284 Triiodothyronine Triiodothyronine results in increased expression of RARA mRNAincreases expression 17403546
D013629 Tamoxifen Tamoxifen affects the expression of RARA mRNAaffects expression 17555576
D013739 Testosterone Testosterone results in decreased expression of RARA mRNAdecreases expression 16432891
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of RARA mRNAaffects cotreatment|decreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of RARA mRNAdecreases expression 19619570
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RARA mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of RARA mRNAincreases expression 15667827
D013876 Thiophenes Thiophenes analog promotes the reaction [Tretinoin results in increased expression of RARA mRNA alternative form]increases expression|increases reaction 16140955
D014212 Tretinoin Tretinoin results in increased expression of RARA mRNAincreases expression 12921748
D014212 Tretinoin caffeic acid phenethyl ester promotes the reaction [Tretinoin results in increased activity of RARA protein]increases activity|increases reaction 16766008
D014212 Tretinoin [decitabine co-treated with Tretinoin] results in increased expression of RARA mRNAaffects cotreatment|increases expression 19524134
D014212 Tretinoin IFNG protein promotes the reaction [Tretinoin results in increased expression of RARA mRNA]increases expression|increases reaction 16007204
D014212 Tretinoin Lipopolysaccharides promotes the reaction [Tretinoin results in increased expression of RARA mRNA]increases expression|increases reaction 17216566
D014212 Tretinoin Melatonin promotes the reaction [Tretinoin results in increased activity of RARA protein]increases activity|increases reaction 15813899
D014212 Tretinoin [PCNA protein binds to RARA protein] which affects the susceptibility to Tretinoinaffects binding|affects response to substance 16055921
D014212 Tretinoin RARA protein affects the reaction [Tretinoin results in decreased secretion of IFNG protein]affects reaction|decreases secretion 16872382
D014212 Tretinoin RARA protein affects the reaction [Tretinoin results in decreased secretion of [IL12A protein binds to IL12B protein]]affects binding|affects reaction|decreases secretion 16872382
D014212 Tretinoin RARA protein affects the reaction [Tretinoin results in increased expression of CYP26A1 mRNA]affects reaction|increases expression 16194896
D014212 Tretinoin RARA protein affects the reaction [Tretinoin results in increased secretion of IL10 protein]affects reaction|increases secretion 16872382
D014212 Tretinoin RARA protein affects the reaction [Tretinoin results in increased secretion of IL4 protein]affects reaction|increases secretion 16872382
D014212 Tretinoin [RARA protein binds to RXRA protein] promotes the reaction [Tretinoin results in increased degradation of NCOA3 protein]affects binding|increases degradation|increases reaction 16456540
D014212 Tretinoin RARA protein promotes the reaction [Tretinoin results in increased activity of STS protein]increases activity|increases reaction 16178010
D014212 Tretinoin RARA protein promotes the reaction [Tretinoin results in increased expression of VEGFA mRNA]increases expression|increases reaction 17170094
D014212 Tretinoin RARA protein results in increased susceptibility to Tretinoinincreases response to substance 16287870
D014212 Tretinoin Ro 41-5253 inhibits the reaction [Tretinoin results in increased expression of RARA mRNA]decreases reaction|increases expression 17216566
D014212 Tretinoin Thiophenes analog promotes the reaction [Tretinoin results in increased expression of RARA mRNA alternative form]increases expression|increases reaction 16140955
D014212 Tretinoin Tretinoin affects the localization of RARA proteinaffects localization 16636311
D014212 Tretinoin [Tretinoin binds to and affects the activity of RARA protein] which results in increased activity of CDKN1A proteinaffects activity|affects binding|increases activity 16765349
D014212 Tretinoin Tretinoin binds to [RXRA protein binds to RARA protein]affects binding 16757381
D014212 Tretinoin [Tretinoin binds to [RXRA protein binds to RARA protein]] which binds to PDK4 promoteraffects binding 16757381
D014212 Tretinoin [Tretinoin co-treated with arsenic trioxide] results in decreased expression of RARA mRNA alternative formaffects cotreatment|decreases expression 19225113
D014212 Tretinoin [Tretinoin co-treated with Butyrates] results in increased cleavage of RARA protein mutant formaffects cotreatment|increases cleavage 12130515
D014212 Tretinoin [Tretinoin co-treated with caffeic acid phenethyl ester] results in increased expression of RARA mRNAaffects cotreatment|increases expression 16766008
D014212 Tretinoin [Tretinoin co-treated with caffeic acid phenethyl ester] results in increased expression of RARA proteinaffects cotreatment|increases expression 16766008
D014212 Tretinoin [Tretinoin co-treated with hexamethylene bisacetamide] results in increased cleavage of RARA protein mutant formaffects cotreatment|increases cleavage 12130515
D014212 Tretinoin [Tretinoin co-treated with RARA protein co-treated with RXRA protein] results in increased expression of CYP26A1 mRNAaffects cotreatment|increases expression 17244623
D014212 Tretinoin Tretinoin inhibits the reaction [BTG2 protein binds to RARA protein]affects binding|decreases reaction 16782888
D014212 Tretinoin Tretinoin inhibits the reaction [CCNH protein binds to and results in increased phosphorylation of RARA protein mutant form]affects binding|decreases reaction|increases phosphorylation 16935935
D014212 Tretinoin Tretinoin inhibits the reaction [PRMT1 protein binds to RARA protein]affects binding|decreases reaction 16782888
D014212 Tretinoin Tretinoin inhibits the reaction [RARA protein mutant form results in decreased expression of SPI1 mRNA]decreases expression|decreases reaction 16352814
D014212 Tretinoin Tretinoin inhibits the reaction [RARA protein mutant form results in decreased expression of SPI1 protein]decreases expression|decreases reaction 16352814
D014212 Tretinoin Tretinoin inhibits the reaction [SIN3A protein binds to RARA protein]affects binding|decreases reaction 16782888
D014212 Tretinoin Tretinoin promotes the reaction [CREBBP protein binds to RARA protein]affects binding|increases reaction 16417649
D014212 Tretinoin Tretinoin promotes the reaction [NCOA3 protein binds to RARA protein]affects binding|increases reaction 16456540
D014212 Tretinoin Tretinoin promotes the reaction [PCNA protein binds to RARA protein]affects binding|increases reaction 16055921
D014212 Tretinoin Tretinoin promotes the reaction [RARA protein binds to CD1D promoter]affects binding|increases reaction 17392484
D014212 Tretinoin Tretinoin promotes the reaction [RARA protein binds to FOLR2 promoter]affects binding|increases reaction 16740727
D014212 Tretinoin Tretinoin promotes the reaction [RARA protein binds to PRAME protein]affects binding|increases reaction 16179254
D014212 Tretinoin Tretinoin promotes the reaction [[RARA protein binds to RXRA protein] which binds to NOS2A promoter]affects binding|increases reaction 17306764
D014212 Tretinoin Tretinoin results in decreased expression of RARA proteindecreases expression 15194426
15375546
16740359
D014212 Tretinoin Tretinoin results in increased activity of RARA proteinincreases activity 16766008
D014212 Tretinoin Tretinoin results in increased activity of [RARA protein binds to RXRA protein]affects binding|increases activity 20008677
D014212 Tretinoin Tretinoin results in increased cleavage of RARA protein mutant formincreases cleavage 12130515
D014212 Tretinoin Tretinoin results in increased degradation of RARA proteinincreases degradation 16456540
D014212 Tretinoin Tretinoin results in increased degradation of RARA protein mutant formincreases degradation 9834237
15748426
19029980
16352814
D014212 Tretinoin Tretinoin results in increased expression of and results in increased activity of RARA proteinincreases activity|increases expression 16158052
D014212 Tretinoin Tretinoin results in increased expression of RARA mRNAincreases expression 16007204
17138961
17216566
17034753
16766008
D014212 Tretinoin Tretinoin results in increased expression of RARA mRNA alternative formincreases expression 16140955
D014212 Tretinoin Tretinoin results in increased expression of RARA proteinincreases expression 16636311
16766008
D014212 Tretinoin Tretinoin results in increased phosphorylation of RARA protein mutant formincreases phosphorylation 19029980
D014212 Tretinoin ZNF366 protein promotes the reaction [Tretinoin results in increased activity of [RARA protein binds to RXRA protein]]affects binding|increases activity|increases reaction 20008677
D014212 Tretinoin RARA protein affects the reaction [Tretinoin affects the expression of CYP26A1 mRNA]affects expression|affects reaction 16261163
D014212 Tretinoin RARA protein affects the reaction [Tretinoin affects the expression of RARB mRNA]affects expression|affects reaction 16261163
D014212 Tretinoin RARA protein inhibits the reaction [Tretinoin results in increased activity of [CLOCK protein binds to ARNTL protein]]affects binding|decreases reaction|increases activity 17069763
D014212 Tretinoin Tretinoin binds to and results in increased activity of RARA proteinaffects binding|increases activity 16839186
12504905
D014212 Tretinoin [Tretinoin binds to RARA protein] which binds to NRL promoteraffects binding 16854989
D014212 Tretinoin Tretinoin results in decreased expression of RARA proteindecreases expression 15646024
D014212 Tretinoin Tretinoin results in increased expression of RARA mRNAincreases expression 8892963
D014212 Tretinoin IL1B protein promotes the reaction [Tretinoin affects the localization of RARA protein]affects localization|increases reaction 17078027
D014212 Tretinoin Tretinoin affects the localization of RARA proteinaffects localization 17078027
D014212 Tretinoin Tretinoin results in increased expression of RARA proteinincreases expression 16043492
D014212 Tretinoin Tretinoin binds to and results in increased activity of RARA proteinaffects binding|increases activity 16839186
D014212 Tretinoin Tretinoin binds to and results in increased activity of RARA proteinaffects binding|increases activity 16819260
D014212 Tretinoin Tretinoin binds to RARA proteinaffects binding 17387344
C012589 trichostatin A trichostatin A promotes the reaction [alitretinoin results in increased activity of RARA protein]increases activity|increases reaction 15773917
C034028 vanadyl sulfate vanadyl sulfate results in decreased expression of RARA mRNAdecreases expression 16330358
D014801 Vitamin A Vitamin A results in increased expression of RARA mRNAincreases expression 12921748
D014801 Vitamin A [Vitamin A co-treated with RARA protein co-treated with RXRA protein] results in increased expression of CYP26A1 mRNAaffects cotreatment|increases expression 17244623
D014801 Vitamin A Vitamin A results in increased expression of RARA mRNAincreases expression 17225872
17034753
D014801 Vitamin A [RARA gene mutant form co-treated with Vitamin A] results in decreased expression of COL2A1 mRNAaffects cotreatment|decreases expression 16397886
D014801 Vitamin A [RARA gene mutant form co-treated with Vitamin A] results in decreased expression of SOX9 mRNAaffects cotreatment|decreases expression 16397886
D014801 Vitamin A [RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS1 mRNAaffects cotreatment|increases expression 16397886
D014801 Vitamin A [RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS2 mRNAaffects cotreatment|increases expression 16397886
D014801 Vitamin A RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of COL2A1 mRNA]affects cotreatment|decreases expression|decreases reaction 16397886
D014801 Vitamin A RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in decreased expression of SOX9 mRNA]affects cotreatment|decreases expression|decreases reaction 16397886
D014801 Vitamin A RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS1 mRNA]affects cotreatment|decreases reaction|increases expression 16397886
D014801 Vitamin A RARG gene mutant form inhibits the reaction [[RARA gene mutant form co-treated with Vitamin A] results in increased expression of MEIS2 mRNA]affects cotreatment|decreases reaction|increases expression 16397886
D002762 Cholecalciferol RARA protein mutant form inhibits the reaction [[Cholecalciferol co-treated with TGFB1 protein] results in increased expression of CD14 mRNA]affects cotreatment|decreases reaction|increases expression 15988048
C111237 vorinostat decitabine promotes the reaction [vorinostat results in increased expression of RARA mRNA]increases expression|increases reaction 17417771
C111237 vorinostat vorinostat results in increased expression of RARA mRNAincreases expression 17417771
D015032 Zinc Zinc results in increased expression of RARA protein mutant formincreases expression 16330433
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.7914745880
MESH:D000014 Abnormalities, Drug-Induced Isotretinoin 10.2518769834
MESH:D000014 Abnormalities, Drug-Induced Phenytoin 10.2510563481 9118846 3425630 6195326 9677735 8986270
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 10.2514514962 15322242 11752688
MESH:D000015 Abnormalities, Multiple Isotretinoin 8.5418769834
MESH:D000015 Abnormalities, Multiple Vitamin A 8.5410992263
MESH:D000138 Acidosis Ammonium Chloride 2.8218287403
MESH:D017486 Acneiform Eruptions Isotretinoin 5.5316232082
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 9.5017505938
MESH:D000152 Acne Vulgaris Isotretinoin 9.5018769834 16185265
MESH:D000169 Acrodermatitis Zinc 4.6616889938 17190629 17202136
MESH:D058186 Acute Kidney Injury Cisplatin 6.9312690470 17670903 15814532
MESH:D058186 Acute Kidney Injury Gentamicins 6.9311274264
MESH:D055371 Acute Lung Injury Lipopolysaccharides 3.3511850527 18653653
MESH:D000230 Adenocarcinoma arsenic trioxide 16.8219825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 16.8220464547 20127859
MESH:D000230 Adenocarcinoma Cisplatin 16.8217638652 11798837
MESH:D000230 Adenocarcinoma Estradiol 16.8211473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 16.8214692618
MESH:D000230 Adenocarcinoma Fenretinide 16.8210697514
MESH:D000230 Adenocarcinoma Methylnitrosourea 16.8215113128 15688392
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 12.073712494
MESH:D000236 Adenoma Benzo(a)pyrene 12.076695378
MESH:D000236 Adenoma Diethylnitrosamine 12.0710737359 6695378
MESH:D000236 Adenoma Melatonin 12.0717195641
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 7.6119061943 17620307 19052882 17162532 16434500 18056438
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 7.6116835633
MESH:D000419 Albuminuria Raloxifene 3.8917308373 17451421
MESH:D019973 Alcohol-Related Disorders Curcumin 11.1217887948
MESH:D019973 Alcohol-Related Disorders puerarin 11.1217887948
MESH:D000505 Alopecia Tretinoin 3.0115955085
MESH:D000544 Alzheimer Disease Curcumin 5.3515590663
MESH:D000544 Alzheimer Disease Raloxifene 5.3515800139
MESH:D000544 Alzheimer Disease Zinc 5.3516580781 17119284 16410023 16325427
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.8211748828
MESH:D000740 Anemia Vitamin A 6.8216960172
MESH:D018798 Anemia, Iron-Deficiency Vitamin A 4.1416960172
MESH:D000755 Anemia, Sickle Cell Zinc 4.1916916123
MESH:D000987 Antisocial Personality Disorder Testosterone 5.107506515
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.3519183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 2.7511256880
MESH:D001169 Arthritis, Experimental Dexamethasone 9.3517659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 9.3515885639
MESH:D001169 Arthritis, Experimental Tretinoin 9.3516412693
MESH:D001172 Arthritis, Rheumatoid Am 80 6.1616819260
MESH:D001172 Arthritis, Rheumatoid Curcumin 6.1616807698
MESH:D001172 Arthritis, Rheumatoid Tretinoin 6.1616292516
MESH:D001249 Asthma epigallocatechin gallate 8.8816516891
MESH:D001249 Asthma Tretinoin 8.8816456186
MESH:D001249 Asthma Vitamin A 8.8816732791
MESH:D001249 Asthma Zinc 8.8817085522
MESH:D050197 Atherosclerosis Am 80 8.5016484594
MESH:D050197 Atherosclerosis Curcumin 8.5018704882
MESH:D050197 Atherosclerosis Phenytoin 8.5015136057
MESH:D001321 Autistic Disorder Melatonin 3.5316919138 16897403
MESH:D001327 Autoimmune Diseases Cholecalciferol 14.1016142846
MESH:D001327 Autoimmune Diseases Curcumin 14.1019761891
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 14.1019761891
MESH:D001471 Barrett Esophagus Tretinoin 3.6916935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.261440618 11289319
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 11.4816206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 11.4812125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 11.4816206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.0415340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.2515746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.1314601052
MESH:D001862 Bone Resorption bisphenol A 3.2011985600
MESH:D001930 Brain Injuries Raloxifene 8.7316580743
MESH:D001930 Brain Injuries Zinc 8.7317109824
MESH:D002545 Brain Ischemia beta Carotene 13.1616157235
MESH:D002545 Brain Ischemia Curcumin 13.1616770732
MESH:D002545 Brain Ischemia puerarin 13.1616041641
MESH:D001932 Brain Neoplasms Curcumin 7.0117596214
MESH:D001932 Brain Neoplasms Fenretinide 7.0116187019
MESH:D001943 Breast Neoplasms 4-(1H-imidazol-1-yl)retinoic acid 16.7617145897 17387344
MESH:D001943 Breast Neoplasms alitretinoin 16.7616344269
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 16.7620146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 16.7617123778
MESH:D001943 Breast Neoplasms Cisplatin 16.7618382427 19526202
MESH:D001943 Breast Neoplasms Curcumin 16.7618593918 18462866 19250217 16243823
MESH:D001943 Breast Neoplasms decitabine 16.7618320071 19208741
MESH:D001943 Breast Neoplasms Diethylnitrosamine 16.7617474063
MESH:D001943 Breast Neoplasms Estradiol 16.7612948864 19861407 17018787 17289903 14630087 16675129 17261762 18497071
MESH:D001943 Breast Neoplasms Fenretinide 16.7616601279
MESH:D001943 Breast Neoplasms Methylnitrosourea 16.7614633655 16253758 11306469
MESH:D001943 Breast Neoplasms Raloxifene 16.7616912660 15758505 17595753 16837676 15775269 17261762 17440819 17049068 17242785 15572757 17952589 17893378
MESH:D001943 Breast Neoplasms Retinoids 16.7617491551 19340624 17368321
MESH:D001943 Breast Neoplasms Tamoxifen 16.7619487384 19115204 18351453 20544844 19059307 19189210 19066611 19288272 18984771 15668708 21138602 17261762 19244106 16202921 17242785 21152245 20065188 20859285 18821012 19200415 17440819 15565566 20005174 19221464 19289846 19189212 20135344 19011961 19410462 18629630 18425577 19084267 18997820 17893378 11161223 18855134 16818667 18815881 19103187 19155303 16873071 19142967 16273361 20390343 17049068
MESH:D001943 Breast Neoplasms Testosterone 16.7617261762
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 16.7620435547
MESH:D001943 Breast Neoplasms Tretinoin 16.7616873071 16443354 16166294
MESH:D001943 Breast Neoplasms vorinostat 16.7616144943
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 10.5716813970
MESH:D001997 Bronchopulmonary Dysplasia Vitamin A 10.5717426644 17377406
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.6411589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.7216111702
MESH:D002252 Carbon Tetrachloride Poisoning Melatonin 4.6015700767
MESH:D002277 Carcinoma Curcumin 6.2818593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.2816835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.7819066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.4016168501
MESH:D006528 Carcinoma, Hepatocellular marker/mechanism 18026104
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 13.683581430 7296757
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 13.6814691202 15553829 15073043 16217749 11135700
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 13.6817982673
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 13.6820007298 17428255 10672840 20727157 19335982 16502159 16878318 10737359 17761372 20214788 19919837 18978308 18506893 18665156 18393292 18785209 20514400 18971187 18210153 20512989 3581430 16830150 3084413 20935162 17138121 19418558 18788625 19394651 16288022 16935385 19539802 21159647 19052882 16698587 17978847 11831363 17173139 16779866 19171122 16540662 17055752 19519916 19701751 20432363 18494052 16569478 16681979 16328049 18691550 18056438 20524982 19208518 20101231 16807293 19822196 17162532 19383236 19107877 20084675
MESH:D006528 Carcinoma, Hepatocellular Estradiol 13.6816924424
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 13.6816270382 17159502
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 13.6816924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 13.681917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.2517123778
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 4.6912023789 16685392
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 4.6918414057
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.1219014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.277296757
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.4612490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 24.4320419170
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 24.4317066447 18337622 6189445
MESH:D002294 Carcinoma, Squamous Cell Curcumin 24.4318462866
MESH:D002294 Carcinoma, Squamous Cell decitabine 24.4319215824
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 24.4316274795
MESH:D002294 Carcinoma, Squamous Cell Isotretinoin 24.4311237771
MESH:D002294 Carcinoma, Squamous Cell retinol palmitate 24.4315984520
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 24.4316051514 16096774
MESH:D002294 Carcinoma, Squamous Cell Zinc 24.4316543248
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 7.3317572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 7.3317572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 1.9118850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases Raloxifene 5.8215775269
MESH:D002318 Cardiovascular Diseases Zinc 5.8216936243
MESH:D002386 Cataract Am 580 9.8417460283
MESH:D002386 Cataract Methylnitrosourea 9.8412484553
MESH:D002386 Cataract Tretinoin 9.8417460283
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 11.617505956
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 11.6121159647 17174075 2727394 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 11.6118566989
MESH:D002471 Cell Transformation, Neoplastic Methylnitrosourea 11.617505956 2727394
MESH:D002493 Central Nervous System Diseases Phenytoin 4.574080065
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 10.5216154183
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 10.5216129372
MESH:D002659 Child Development Disorders, Pervasive Testosterone 3.3520678186
MESH:D015362 Child Nutrition Disorders Vitamin A 4.7216153327
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 7.2119052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.2116835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 10.249022650 19486331
MESH:D002779 Cholestasis Ethinyl Estradiol 10.2415861022 17681005 17110522 16105132 17333356 11677210 16919318
MESH:D002779 Cholestasis Vitamin A 10.2416175620
OMIM:601042 CHOREOATHETOSIS/SPASTICITY, EPISODIC Phenytoin 5.1311748493
MESH:D002822 Choriocarcinoma Tretinoin 4.4016461808
MESH:D002971 Cleft Lip Phenytoin 3.712227380
MESH:D002972 Cleft Palate Phenytoin 11.033877104 2227380 6862529 10789828 6856622 1687470
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 11.0315668235 8697196 12621046 15340226 16354765
MESH:D002972 Cleft Palate Tretinoin 11.039407595
MESH:D002972 Cleft Palate Vitamin A 11.0316054864
MESH:D003072 Cognition Disorders Raloxifene 3.9015800139
MESH:D003092 Colitis Am 580 12.0617035595
MESH:D003092 Colitis Curcumin 12.0616804969 18200517 16782535
MESH:D003092 Colitis Tretinoin 12.0617035595
MESH:D003103 Coloboma Curcumin 9.1018809619
MESH:D003103 Coloboma Phenytoin 9.109212184
MESH:D003110 Colonic Neoplasms Butyrates 11.3715936596
MESH:D003110 Colonic Neoplasms Curcumin 11.3716340194 19359593
MESH:D003110 Colonic Neoplasms decitabine 11.3717616700
MESH:D003110 Colonic Neoplasms Deoxycholic Acid 11.3716213893
MESH:D003110 Colonic Neoplasms Dexamethasone 11.3715824018
MESH:D003110 Colonic Neoplasms Vitamin A 11.3717219422 16267017
MESH:D015179 Colorectal Neoplasms arsenic trioxide 5.2920501625
MESH:D015179 Colorectal Neoplasms Cisplatin 5.2915273666
MESH:D015179 Colorectal Neoplasms decitabine 5.2918981723
MESH:D015179 Colorectal Neoplasms Fenretinide 5.2917273769
MESH:D015179 Colorectal Neoplasms Polychlorinated Biphenyls 5.2915531428
MESH:D000013 Congenital Abnormalities Phenytoin 7.2710627286
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 7.2714669216 17141729
MESH:D016510 Corneal Neovascularization Curcumin 4.1718497527
MESH:D023903 Coronary Restenosis arsenic trioxide 3.4812609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 14.1610525206
MESH:D019465 Craniofacial Abnormalities Dexamethasone 14.1617728286
MESH:D019465 Craniofacial Abnormalities Isotretinoin 14.1618769834 9879862
MESH:D019465 Craniofacial Abnormalities nitrofen 14.1611405365
MESH:D019465 Craniofacial Abnormalities Phenytoin 14.168986270 19952982 9212184
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 14.1615322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 14.1616925845 9211117 9142499 8800419 9125849 9664655 14991402 9224671 10589399 17551590
MESH:D019465 Craniofacial Abnormalities Vitamin A 14.1610992263
MESH:D019465 Craniofacial Abnormalities Zinc 14.1619302082
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.4115213294
MESH:D003704 Dementia Polychlorinated Biphenyls 4.0316140633
MESH:D003711 Demyelinating Diseases Tamoxifen 3.6419031437
MESH:D003865 Depressive Disorder, Major Raloxifene 3.5217474826
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 7.668156756 12868966 18759878 8970840 2524372 11298694 11906362 14531868
MESH:D017449 Dermatitis, Allergic Contact cobaltous chloride 7.6611298694 15059100 16823706
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 7.6612438553
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 2.812952479 3621924
MESH:D003920 Diabetes Mellitus Zinc 3.5716479319
MESH:D003921 Diabetes Mellitus, Experimental vanadyl sulfate 3.7616684804
MESH:D003922 Diabetes Mellitus, Type 1 Vitamin A 3.2316506275
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 8.1618403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 8.1620387270
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 8.1616988119
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 8.1617107852
MESH:D003928 Diabetic Nephropathies Curcumin 16.2418204486
MESH:D003928 Diabetic Nephropathies Estradiol 16.2419279558
MESH:D003928 Diabetic Nephropathies Raloxifene 16.2417308373 17451421 15920148
MESH:D003928 Diabetic Nephropathies Tamoxifen 16.2419279558
MESH:D003967 Diarrhea Dexamethasone 6.237237001
MESH:D003967 Diarrhea vorinostat 6.2320479100
OMIM:607208 DRAVET SYNDROME Phenytoin 4.6711748493
MESH:D003875 Drug Eruptions Phenytoin 4.7815024534
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 6.6311289319 16192314 6482804 9022650 18289764 7440962 18692083 18648102 9328219 8291058 6679447 1440618 9653073
MESH:D056486 Drug-Induced Liver Injury Chlorpromazine 6.6311461765
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 6.6319107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.6320420201
MESH:D004362 Drug Toxicity Cisplatin 10.5512649298 12231392 19839026 15033597
MESH:D004362 Drug Toxicity Gentamicins 10.5515033597 11033412
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 10.5511462148
MESH:D015352 Dry Eye Syndromes Vitamin A 5.0616146918
MESH:D004381 Duodenal Ulcer Curcumin 3.3517351913
MESH:D050171 Dyslipidemias Fenofibrate 3.8616707586
MESH:C538011 Eales disease Vitamin A 4.879068938
MESH:D004480 Ectromelia Vitamin A 5.0716054864
MESH:D004485 Eczema Dexamethasone 3.7612438553
MESH:D004487 Edema Dexamethasone 7.7719703484
MESH:D004487 Edema Raloxifene 7.7715860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 7.7712711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 9.4418230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 9.4418230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Am 80 21.3716819260
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 21.3712538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Phenytoin 21.3717654737
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 21.3715845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 21.3719031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 11.5319294695
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 11.5319294695
MESH:D016889 Endometrial Neoplasms Estradiol 13.5111473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Fenofibrate 13.5116569247
MESH:D016889 Endometrial Neoplasms Tamoxifen 13.5116202921 17893378 19155303 20544844
MESH:D016889 Endometrial Neoplasms Tretinoin 13.5116569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.3710568697 9294722
MESH:D019446 Endotoxemia Lipopolysaccharides 3.6615821434 17637181 15328337
MESH:D004816 Epidermal Necrolysis, Toxic Phenytoin 4.4920235791
MESH:D004820 Epidermolysis Bullosa Phenytoin 5.481399206 6251365
MESH:D004828 Epilepsies, Partial Phenytoin 4.1717116037 11558140
MESH:D004827 Epilepsy Phenytoin 3.51821787 11434505 20417680
MESH:D017029 Epilepsy, Complex Partial Phenytoin 4.577750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenytoin 4.333659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.3616302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 10.983581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 10.9812903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 10.9816530937
MESH:D004938 Esophageal Neoplasms Cisplatin 10.9816481741 15173087 16785472 17638652 15464296
MESH:D004938 Esophageal Neoplasms Zinc 10.9816543248
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 6.9111564622
MESH:D005124 Eye Abnormalities Tretinoin 6.9116938888 9664655
MESH:D015785 Eye Diseases, Hereditary Retinoids 5.2716968212
MESH:D005221 Fatigue vorinostat 4.8620479100
MESH:D005234 Fatty Liver arsenic trioxide 22.1615073043
MESH:D005234 Fatty Liver Curcumin 22.1619297423
MESH:D005234 Fatty Liver Diethylnitrosamine 22.1621071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 22.1615345470
MESH:D005234 Fatty Liver Raloxifene 22.1617473493
MESH:D005234 Fatty Liver Tamoxifen 22.1619224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.7416709447
MESH:D005313 Fetal Death Phenytoin 8.3410627286
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 8.3411858732
MESH:D005327 Fetal Resorption Vitamin A 4.6116054864
MESH:D005334 Fever Lipopolysaccharides 3.3711852909 9205823
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.266705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.7914745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.4419069698
MESH:D005354 Fibrosarcoma Methylnitrosourea 4.4911555667
MESH:D005355 Fibrosis Curcumin 10.6918705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 10.6920067830
MESH:D005355 Fibrosis Tretinoin 10.6917994277
MESH:D005391 Firesetting Behavior Testosterone 5.107506515
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.5616904648
MESH:D005756 Gastritis Zinc 4.0517241300
MESH:D005770 Gastrointestinal Neoplasms Curcumin 3.9718462866
MESH:D005885 Gingival Hyperplasia Phenytoin 4.929029455
MESH:D019214 Gingival Overgrowth Phenytoin 5.4816390469 14659971
MESH:D005909 Glioblastoma Curcumin 21.0217596214
MESH:D005909 Glioblastoma Fenretinide 21.0216187019
MESH:D005909 Glioblastoma Okadaic Acid 21.0217312396
MESH:D005909 Glioblastoma Testosterone 21.0217162496
MESH:D005909 Glioblastoma Tretinoin 21.0217312396
MESH:D005909 Glioblastoma trichostatin A 21.0218801729
MESH:D005910 Glioma Methylnitrosourea 3.219825942
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.357505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.8410696789
MESH:D006130 Growth Disorders Zinc 3.4417217573
MESH:D006258 Head and Neck Neoplasms Cisplatin 23.2315102660 15464296
MESH:D006258 Head and Neck Neoplasms Curcumin 23.2318462866 18829502
MESH:D006258 Head and Neck Neoplasms decitabine 23.2319215824
MESH:D006258 Head and Neck Neoplasms Retinoids 23.2317368321
MESH:D006258 Head and Neck Neoplasms retinol palmitate 23.2315984520
MESH:D006258 Head and Neck Neoplasms Tretinoin 23.2316096774
MESH:D034381 Hearing Loss Cisplatin 8.1719898482
MESH:D034381 Hearing Loss Gentamicins 8.1719130971 17868369 18024279 15968427
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.4016084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.7915464296
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 16.3120471113
MESH:D006330 Heart Defects, Congenital nitrofen 16.3116080930
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 16.3110048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 16.3114991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin A 16.3116080930 10992263
MESH:D006331 Heart Diseases Raloxifene 3.0011110106
MESH:D006333 Heart Failure Zinc 3.1217162251
MESH:D006335 Heart Injuries Zinc 5.0117074742
MESH:D016481 Helicobacter Infections Zinc 3.8517241300
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.7316366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.6711000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 2.826705139
MESH:D006527 Hepatolenticular Degeneration Zinc 3.9717276780
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.1912621046 15340226 16120746
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.3117701891
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 7.947520565
MESH:D006548 Hernia, Diaphragmatic nitrofen 7.9412407540 10359170 15578192 17270546 10370016 12746050 15185205 12194112 11051153 10370017 10898224 15136996 10693666 18280291 17618886 17245593 16720372 12505043 11409163 9476886 11057544 9575882 9473106 7760232 12904592 16863852 9698600 16292651 12021965 7576705 15756563 15793718 12759764 10541330 18958481 10898222 7520565 15088113 18280292 11076806 11584395 11685700 11329586 15764645 9859898 15707848 10646786 16490937 8863223 16473863 16080930 11588001 12547725
MESH:D006548 Hernia, Diaphragmatic Vitamin A 7.9416877224 16863852 15707848 16490937 16292552 17436238
MESH:D006558 Herpes Genitalis Estradiol 4.2815709030
MESH:D006561 Herpes Simplex Chlorpromazine 4.561682908
MESH:D006628 Hirsutism Testosterone 4.9017019078
MESH:D015658 HIV Infections beta Carotene 5.8016960176
MESH:D015658 HIV Infections Vitamin A 5.8016960176
MESH:D006679 HIV Seropositivity Vitamin A 4.8617209195
MESH:D006689 Hodgkin Disease Cisplatin 2.9916200630 16170182
MESH:D019584 Hot Flashes Estradiol 3.0117088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.298697196 18606429 16354765 15340226 16959395
MESH:D006930 Hyperalgesia Alendronate 6.3716769263
MESH:D006930 Hyperalgesia Tretinoin 6.3716870215
MESH:D017588 Hyperandrogenism Testosterone 4.5517019078
MESH:D053565 Hypercalciuria Gentamicins 4.9717652376
MESH:D006937 Hypercholesterolemia Curcumin 3.3918704882
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.8416778211
MESH:D020138 Hyperhomocysteinemia Phenytoin 4.0410459572
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.2215034207
MESH:D006973 Hypertension Dexamethasone 6.6417042910
MESH:D006973 Hypertension Raloxifene 6.6417577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 6.6418670907 18850075
MESH:D006986 Hypervitaminosis A Vitamin A 5.4116054864
MESH:D007006 Hypogonadism Testosterone 4.0312002444
MESH:D007018 Hypopituitarism Testosterone 5.4517426086
MESH:D007021 Hypospadias Ethinyl Estradiol 3.0916945680 16569931
MESH:D007174 Impulse Control Disorders Testosterone 5.107506515
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.7812013081
MESH:D007248 Infertility, Male decitabine 8.2617581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 8.2617937319
MESH:D007248 Infertility, Male Methylnitrosourea 8.267193160
MESH:D007249 Inflammation Curcumin 14.2116956363 17151092 18403477
MESH:D007249 Inflammation Dexamethasone 14.2111099482 8960868
MESH:D007249 Inflammation Diethylnitrosamine 14.2118785209
MESH:D007249 Inflammation Lipopolysaccharides 14.2117237260 17963957 12878042 9205823 17255318
MESH:D007249 Inflammation Tamoxifen 14.2119457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 14.2112200463 12878042
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.8518596194 18200517
MESH:D007333 Insulin Resistance bisphenol A 5.6916393666
MESH:D007333 Insulin Resistance Estradiol 5.6916393666 16627594
MESH:D007410 Intestinal Diseases Tretinoin 3.0517994277
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 7.9310783313
MESH:D007414 Intestinal Neoplasms Curcumin 7.9310783313
MESH:D019586 Intracranial Hypertension Vitamin A 5.0715955940
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 3.9417255318
MESH:D007511 Ischemia Zinc 3.9116584753
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.268074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 7.7116580747
MESH:D007569 Jaw Abnormalities Tretinoin 7.7115992940 17551590
MESH:D017492 Keratosis, Seborrheic alitretinoin 4.9016144296
MESH:D007673 Kidney Cortex Necrosis Cisplatin 10.8215464296
MESH:D007673 Kidney Cortex Necrosis Gentamicins 10.8218842672
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 14.0515369732
MESH:D007674 Kidney Diseases Cisplatin 14.0519839026 12649298 12231392 15190930 18289764
MESH:D007674 Kidney Diseases Estradiol 14.0515618244
MESH:D007674 Kidney Diseases Gentamicins 14.0517934191 18289764 19349640
MESH:D007674 Kidney Diseases Zinc 14.0516960431
MESH:D007676 Kidney Failure, Chronic Zinc 3.7516518626
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 8.866582329
MESH:D007680 Kidney Neoplasms Estradiol 8.8615610895
MESH:D007680 Kidney Neoplasms Tamoxifen 8.8618625569
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 9.5111231351
MESH:D007683 Kidney Tubular Necrosis, Acute Gentamicins 9.5111231351
MESH:D007889 Leiomyoma Curcumin 8.8718555241
MESH:D007889 Leiomyoma Raloxifene 8.8716973256
MESH:D016773 Leishmaniasis, Cutaneous Gentamicins 3.8510219319
MESH:D007898 Leishmaniasis, Visceral Antimony Potassium Tartrate 3.9812707265
MESH:D007938 Leukemia arsenic trioxide 11.4315070760
MESH:D007938 Leukemia Curcumin 11.4318462866
MESH:D007938 Leukemia decitabine 11.4319235587 18980019
MESH:D007938 Leukemia Tretinoin 11.4317143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 7.5412560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 7.5416106398
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.5716972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 2.8614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 22.8819077051
MESH:D007951 Leukemia, Myeloid decitabine 22.8818454857 19117987 17236224
MESH:D007951 Leukemia, Myeloid Hydroxyurea 22.8816532439
MESH:D007951 Leukemia, Myeloid Retinoids 22.8816482212
MESH:D007951 Leukemia, Myeloid Tretinoin 22.8816482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 9.5320471514 16968895 16467208 17050201 19850784
MESH:D015470 Leukemia, Myeloid, Acute arsenic trisulfide 9.5317708794
MESH:D015470 Leukemia, Myeloid, Acute decitabine 9.5318704418 19387464 18206229 17679729 18460780 19010910
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 9.5317596541 19850784 16294345
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 9.5318206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.7118055864
MESH:D015473 Leukemia, Promyelocytic, Acute marker/mechanism 17649720 17712046 16239915 16788101 16835227 16935935 19029980 19035177 17294898 14706140 16891316
MESH:D015473 Leukemia, Promyelocytic, Acute Am 80 27.7816531727 16819260
MESH:D015473 Leukemia, Promyelocytic, Acute Antimony Potassium Tartrate 27.789834237
MESH:D015473 Leukemia, Promyelocytic, Acute antimony trioxide 27.789834237
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 27.7811161223 16112521 19642359 15622746 17107899 15748426 19035177 9834237 17649720 16331271 12712474 12018890 19225113 12679006 16966277 16330433 16823087 17869043 16891316 17217047 15213294 11468182 17712046 15336539 19075265
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 27.7816766008
MESH:D015473 Leukemia, Promyelocytic, Acute Thiophenes 27.7816140955 16140954
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 27.7817506722 16331271 12679006 17217047 17361223 16140955 16788101 17368321 17107899 9834237 19642359 15748426 16823087 19029980 17649720 19035177 19075265 16766008 17294898 16935935 17712046 17301526 19225113 16891316 17339181
MESH:D015458 Leukemia, T-Cell arsenic trioxide 9.3716882451
MESH:D015458 Leukemia, T-Cell Curcumin 9.3716106398
MESH:D007970 Leukopenia Lipopolysaccharides 3.9615821434
MESH:D007972 Leukoplakia, Oral Fenretinide 5.2916707609
MESH:D017880 Limb Deformities, Congenital Methylnitrosourea 10.6315526292
MESH:D017880 Limb Deformities, Congenital Tretinoin 10.639224671
MESH:D017880 Limb Deformities, Congenital Vitamin A 10.6316054864
MESH:D008064 Lipidoses Chlorpromazine 6.5117567588 15342952
MESH:D008064 Lipidoses Tamoxifen 6.5115342952 17567588
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 8.7318665156 18407596 20032147 19638242 18522880
MESH:D008103 Liver Cirrhosis puerarin 8.7316426832
MESH:D008103 Liver Cirrhosis Vitamin A 8.7316256175
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.699327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 17.2718006644 17355460 18705752
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 17.2716718785
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 17.2717481882
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 17.2714659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Fenofibrate 17.2715474484
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 17.2712878042
MESH:D008106 Liver Cirrhosis, Experimental Melatonin 17.2716703270 15298665 15925388
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 17.2718564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 17.2712878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 17.2718397230 16248980
MESH:D008106 Liver Cirrhosis, Experimental Vitamin A 17.2716248980
MESH:D008107 Liver Diseases Chlorpromazine 12.4114986274
MESH:D008107 Liver Diseases Curcumin 12.4116956363
MESH:D008107 Liver Diseases Diethylnitrosamine 12.4117034775
MESH:D008107 Liver Diseases limonene 12.411715830
MESH:D008107 Liver Diseases Phenytoin 12.4114986274
MESH:D008107 Liver Diseases Vitamin A 12.4116175620
MESH:D008108 Liver Diseases, Alcoholic Vitamin A 4.4316762690
MESH:D008113 Liver Neoplasms arsenic trioxide 13.3914682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 13.3921137059 20195826
MESH:D008113 Liver Neoplasms Diethylnitrosamine 13.3918754104 9163691 12112319 18648771 19690152 20118626 19427195 19254457 19426721 18978307 21278145 21071580 20452335 19850985 16942905 20434301 19812893 19551842 20137499 19256749 12771043 2422723 19499222 19642983 19833225 2862719 19638242 19090486 18644402 19073162 21047994 20101389 18977376 20405173 15175105 19996281 15885732 10737359 20492335 20583210 19255062 19294768 21167192 20501860
MESH:D008113 Liver Neoplasms Fenofibrate 13.3918978307
MESH:D008113 Liver Neoplasms Tamoxifen 13.3916684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 13.3916984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 32.541399818 6587162 598648 3712494
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 32.5420377131
MESH:D008114 Liver Neoplasms, Experimental beta Carotene 32.5417113696
MESH:D008114 Liver Neoplasms, Experimental Deoxycholic Acid 32.546150874
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 32.5418079962 21159647 19539802 17942915 18544905 18282651 3124819 18164116 19126423 17854601 19009564 2563599 18093689 19519916 16267830 18253720 18775883 18308698 19004024 16842330 9362446 17174075
MESH:D008114 Liver Neoplasms, Experimental Fenofibrate 32.5418775883 18253720
MESH:D008114 Liver Neoplasms, Experimental kojic acid 32.5418544905
MESH:D008114 Liver Neoplasms, Experimental Polychlorinated Biphenyls 32.541423854
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 32.5412151625
MESH:D008114 Liver Neoplasms, Experimental Vitamin A 32.5417113696
MESH:D008133 Long QT Syndrome arsenic trioxide 2.7715213294
MESH:D038061 Lower Extremity Deformities, Congenital Methylnitrosourea 4.7416080182
MESH:D008171 Lung Diseases nitrofen 6.4616863852 9614859 17245593 9859898
MESH:D008171 Lung Diseases Vitamin A 6.4616863852
MESH:D055370 Lung Injury Lipopolysaccharides 3.3021114838
MESH:D008175 Lung Neoplasms alitretinoin 21.8016413115
MESH:D008175 Lung Neoplasms arsenic trioxide 21.8011798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 21.8017053015 20869020 20464547 20064080 18520028 6695378 20135361 18816296 18569708
MESH:D008175 Lung Neoplasms beta Carotene 21.8016401635
MESH:D008175 Lung Neoplasms Cisplatin 21.8017225452 11798837 6189445
MESH:D008175 Lung Neoplasms Curcumin 21.8019359593 16243823 18462866
MESH:D008175 Lung Neoplasms Dexamethasone 21.8015824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 21.8020512841 20970405 6695378 21163286
MESH:D008175 Lung Neoplasms Isotretinoin 21.8015899809
MESH:D008175 Lung Neoplasms Melatonin 21.8017195641
MESH:D008175 Lung Neoplasms Methylnitrosourea 21.8018062963
MESH:D008175 Lung Neoplasms Tamoxifen 21.8018625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 21.8011884234 19555203
MESH:D008180 Lupus Erythematosus, Systemic Melatonin 3.6516373423
MESH:D008223 Lymphoma Curcumin 9.4918462866
MESH:D008223 Lymphoma decitabine 9.4919470736
MESH:D008223 Lymphoma Methylnitrosourea 9.4916257854 11418001
MESH:D016393 Lymphoma, B-Cell Methylnitrosourea 4.0914633661
MESH:D016399 Lymphoma, T-Cell Curcumin 3.9716173963
MESH:D016410 Lymphoma, T-Cell, Cutaneous vorinostat 4.9620479100
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.0319428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 13.3911408345 11807958 17203775 16891317
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 13.3910697514
MESH:D008325 Mammary Neoplasms, Experimental Methylnitrosourea 13.3915313902 14633655 10767621 16827153 15113128 19196723 11751437 17020996 16619500 12931682 11807958 16944150 10838139 17131329 15688392 16051031 14999141
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 13.3919196723 11731420 19196722 14580682 16827153
MESH:D008325 Mammary Neoplasms, Experimental Zinc 13.3912773700
MESH:D020149 Manganese Poisoning Estradiol 10.1519453300
MESH:D020149 Manganese Poisoning Tamoxifen 10.1519453300
MESH:D008415 Mastocytosis Retinoids 5.8416953078
MESH:D008527 Medulloblastoma Tretinoin 2.4317453147
MESH:D008545 Melanoma Cisplatin 17.6017761969 16432458 16248763 16809738 18332650 18505091 12374674 17023156 12883367 15577323 12393984 18176117 11135225
MESH:D008545 Melanoma Curcumin 17.6017885582 18462866
MESH:D008545 Melanoma decitabine 17.6017785578 16505122
MESH:D008545 Melanoma epigallocatechin gallate 17.6017992120 11746506
MESH:D008545 Melanoma Fenretinide 17.6016270382
MESH:D008545 Melanoma Isotretinoin 17.6017237267
MESH:D008545 Melanoma Tamoxifen 17.6019393235 12393984
MESH:D008545 Melanoma Tretinoin 17.6016752155
MESH:D008545 Melanoma trichostatin A 17.6016505122
MESH:D018328 Melanoma, Amelanotic Cisplatin 9.0615990972
MESH:D018328 Melanoma, Amelanotic Tamoxifen 9.0615990972
MESH:D008569 Memory Disorders Curcumin 3.4617263510
MESH:D008591 Meningomyelocele Tretinoin 3.7016940565
MESH:D001523 Mental Disorders Chlorpromazine 4.0316856516
MESH:D008607 Mental Retardation Phenytoin 3.369212184
MESH:D008654 Mesothelioma Cisplatin 5.8917638057
MESH:D008654 Mesothelioma hexamethylene bisacetamide 5.8915543656
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 4.8015863610
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 6.8216381670
MESH:D009062 Mouth Neoplasms Fenretinide 6.8216274795
MESH:D009101 Multiple Myeloma Am 80 30.1817229644
MESH:D009101 Multiple Myeloma arsenic trioxide 30.1814977855 15949261 19417148 11468182 19549372
MESH:D009101 Multiple Myeloma Curcumin 30.1819372569
MESH:D009101 Multiple Myeloma decitabine 30.1818172295
MESH:D009101 Multiple Myeloma Dexamethasone 30.1815867202 15744524 16118317
MESH:D009101 Multiple Myeloma Raloxifene 30.1816497877
MESH:D009101 Multiple Myeloma trichostatin A 30.1818172295
MESH:D009101 Multiple Myeloma Vitamin A 30.1816374440
MESH:D009103 Multiple Sclerosis 4-Aminopyridine 5.1019915712
MESH:D009134 Muscular Atrophy, Spinal Curcumin 10.1917962980
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 10.1917962980
MESH:D009137 Muscular Dystrophy, Animal Gentamicins 5.5218694830
MESH:D009175 Mycoplasma Infections Chlorpromazine 5.2410773494
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.9218349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 13.6716882451 16105982
MESH:D009190 Myelodysplastic Syndromes decitabine 13.6719010910 16882708 18608210 19157545
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 13.679809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 13.6717596541
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.4112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 2.6916810080
MESH:D020191 Myoclonic Epilepsies, Progressive Phenytoin 4.7817484760
MESH:D009224 Myotonia Congenita Phenytoin 4.671896199
MESH:D009232 Myxoma Raloxifene 4.8016343187
MESH:D009325 Nausea vorinostat 4.7720479100
MESH:D009336 Necrosis Melatonin 4.7312195237
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 7.9916624393
MESH:D009361 Neoplasm Invasiveness Curcumin 7.9918495463
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 7.323581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 7.323581430 9029167
MESH:D009362 Neoplasm Metastasis Tamoxifen 7.3219393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.2219410462
MESH:D009369 Neoplasms alitretinoin 20.8716946489
MESH:D009369 Neoplasms Benzo(a)pyrene 20.8711141357
MESH:D009369 Neoplasms beta Carotene 20.8717051425
MESH:D009369 Neoplasms Cisplatin 20.8716773208
MESH:D009369 Neoplasms decitabine 20.8719116145 17925555 19470736
MESH:D009369 Neoplasms Fenretinide 20.8715958647 17353921
MESH:D009369 Neoplasms Methylnitrosourea 20.8715533788
MESH:D009369 Neoplasms Tretinoin 20.8716594593 16946489
MESH:D009374 Neoplasms, Experimental Methylnitrosourea 3.7612696579
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 8.3512497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 8.3519189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.0017289903
MESH:D009395 Nephritis, Interstitial Cisplatin 3.7415464296
MESH:D009421 Nervous System Malformations bisphenol A 17.6916427766 11399458
MESH:D009421 Nervous System Malformations Estradiol 17.6916427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 17.6914600291
MESH:D009421 Nervous System Malformations Tretinoin 17.699125849
MESH:D009423 Nervous System Neoplasms Curcumin 4.8718462866
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 17.256679447
MESH:D009436 Neural Tube Defects arsenic trioxide 17.2510525206
MESH:D009436 Neural Tube Defects Phenytoin 17.259118846
MESH:D009436 Neural Tube Defects Tretinoin 17.259142499
MESH:D009436 Neural Tube Defects Vitamin A 17.2517400914
MESH:D009442 Neurilemmoma Methylnitrosourea 4.7511555667
MESH:D009447 Neuroblastoma Cisplatin 5.968761367
MESH:D009447 Neuroblastoma Isotretinoin 5.9617368321
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 2.7320387270
MESH:D017599 Neuroectodermal Tumors Cisplatin 3.968761367
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.3620387270
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 4.9416303764
MESH:D009765 Obesity Curcumin 2.5219297423
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 2.776482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.263988306
MESH:D010018 Osteomalacia Phenytoin 4.6717016548
MESH:D010024 Osteoporosis Alendronate 9.2117882678
MESH:D010024 Osteoporosis Curcumin 9.2118719352
MESH:D010024 Osteoporosis Raloxifene 9.2117882678 15775268 19059307
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 3.5417823083 15579764 17893378 15758505
MESH:D010033 Otitis Media retinol palmitate 6.1317303254
MESH:D010049 Ovarian Diseases bisphenol A 4.2511985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 21.6912452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Cisplatin 21.6915464296 19769630 6897625 17225452
MESH:D010051 Ovarian Neoplasms Curcumin 21.6919020741 18462866
MESH:D010051 Ovarian Neoplasms decitabine 21.6919331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 21.6919401270
MESH:D010051 Ovarian Neoplasms Fenretinide 21.6916133793
MESH:D010051 Ovarian Neoplasms Tretinoin 21.6916936753
MESH:D010051 Ovarian Neoplasms trichostatin A 21.6919331143
MESH:D010146 Pain Phenytoin 5.1715215642
MESH:D010146 Pain Tretinoin 5.1716870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 27.2515580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 27.2519003803
MESH:D010190 Pancreatic Neoplasms Curcumin 27.2519196508 17440100 19401701
MESH:D010190 Pancreatic Neoplasms decitabine 27.2519294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 27.2516540662
MESH:D010190 Pancreatic Neoplasms Fenretinide 27.2515580305
MESH:D010190 Pancreatic Neoplasms Methylnitrosourea 27.2516965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 27.2515976015
MESH:D010190 Pancreatic Neoplasms trichostatin A 27.2519294695
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.0011578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 2.777296757
MESH:D010235 Paraganglioma arsenic trioxide 3.4719927285
MESH:D010300 Parkinson Disease Polychlorinated Biphenyls 3.0716702228
MESH:D020734 Parkinsonian Disorders Melatonin 4.3915574749
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.4912520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.6115464296
MESH:D010538 Peritonitis Melatonin 4.6015707874
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 3.726228378
MESH:D010997 Pleural Neoplasms Cisplatin 4.5917638057
MESH:D011014 Pneumonia Lipopolysaccharides 3.8211605937 12224865
MESH:D017689 Polydactyly Phenytoin 4.409212184
MESH:D017499 Porokeratosis alitretinoin 5.2516144296
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.8518163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 2.922563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.0821297632
MESH:D011225 Pre-Eclampsia Zinc 3.5817114810
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 12.1410548101
MESH:D011297 Prenatal Exposure Delayed Effects Isotretinoin 12.1418769834
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 12.1411118676 11896295 11399792 11222880
MESH:D055728 Primary Myelofibrosis decitabine 10.0217616702
MESH:D055728 Primary Myelofibrosis trichostatin A 10.0217616702
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 14.1820887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 14.1820887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Testosterone 14.1820887781
MESH:D011471 Prostatic Neoplasms Am 80 7.6616289102
MESH:D011471 Prostatic Neoplasms arsenic trioxide 7.6619131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 7.6617292933
MESH:D011471 Prostatic Neoplasms bisphenol A 7.6616740699
MESH:D011471 Prostatic Neoplasms Cholecalciferol 7.6617024972
MESH:D011471 Prostatic Neoplasms Curcumin 7.6618156803 11398177 12497104 18769126 15129424 10851300 18226269
MESH:D011471 Prostatic Neoplasms Estradiol 7.6616740699
MESH:D011471 Prostatic Neoplasms Fenretinide 7.6617024972
MESH:D011471 Prostatic Neoplasms Methylnitrosourea 7.6615682402 12376480
MESH:D011471 Prostatic Neoplasms Polychlorinated Biphenyls 7.6615721890
MESH:D011471 Prostatic Neoplasms Raloxifene 7.6616220300 16536755 15731164
MESH:D011471 Prostatic Neoplasms Retinoids 7.6616724957 16166285
MESH:D011471 Prostatic Neoplasms Tamoxifen 7.6615067354
MESH:D011471 Prostatic Neoplasms trichostatin A 7.6618798265 19789329
MESH:D011471 Prostatic Neoplasms vorinostat 7.6617218635
MESH:D011471 Prostatic Neoplasms Zinc 7.6616700911 12429649 16606632 16517595
MESH:D011507 Proteinuria Gentamicins 7.2715033597
MESH:D011507 Proteinuria Tretinoin 7.2716636307
MESH:D011537 Pruritus Ethinyl Estradiol 2.5815861022 16919318
MESH:D019310 Pseudolymphoma Phenytoin 4.798603615 1419762 12752131
MESH:D011565 Psoriasis Am 80 3.7716819260
MESH:D011596 Psychomotor Disorders Isotretinoin 5.1818769834
MESH:D011625 Pterygium Tretinoin 4.0516723453
MESH:D011629 Puberty, Precocious bisphenol A 4.0510548101
MESH:D011656 Pulmonary Emphysema Curcumin 3.8719168576
MESH:D011693 Purpura Raloxifene 4.8015770314
MESH:D051437 Renal Insufficiency Cisplatin 8.2715464296
MESH:D051437 Renal Insufficiency Gentamicins 8.2715728788 17132701
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 7.0410666014 18379247
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 7.0418379247 11700416
MESH:D012127 Respiratory Distress Syndrome, Newborn Vitamin A 5.0616877224
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.2110835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.1318990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 16.613692021
MESH:D012162 Retinal Degeneration Fenretinide 16.6116303925
MESH:D012162 Retinal Degeneration Methylnitrosourea 16.6118155124 18172121
MESH:D012162 Retinal Degeneration Zinc 16.6116584753
MESH:D012173 Retinitis Gentamicins 5.5218644591
MESH:D012175 Retinoblastoma Methylnitrosourea 4.7511555667
MESH:D012208 Rhabdomyosarcoma decitabine 8.6619155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 8.6616116481 16283617
MESH:D012509 Sarcoma Curcumin 3.4718462866
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 8.0116646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 8.0114601052
MESH:D020426 Sciatic Neuropathy marker/mechanism 16782282
MESH:D012640 Seizures Dizocilpine Maleate 5.2817157343 12660363 11218047
MESH:D012640 Seizures Phenytoin 5.283691417 19919933 16876388 10029267 3137016 15946322 9844417 11044598
MESH:D018805 Sepsis Curcumin 3.4618389075
MESH:D012735 Sexual Dysfunction, Physiological Testosterone 5.4516631401
MESH:D012871 Skin Diseases Vitamin A 3.1218709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 17.1310029692 19755658
MESH:D012878 Skin Neoplasms Fenretinide 17.1316467112
MESH:D012878 Skin Neoplasms Okadaic Acid 17.1312628509
MESH:D012878 Skin Neoplasms Retinoids 17.1317538947
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 17.1316192470
MESH:D012878 Skin Neoplasms Tretinoin 17.1316467112
MESH:D012893 Sleep Disorders Melatonin 4.7316919138 16897403 18182647
MESH:D020178 Sleep Disorders, Circadian Rhythm Melatonin 5.8818078449 19452292
MESH:D007319 Sleep Initiation and Maintenance Disorders Melatonin 4.5118078449
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.5915464296
MESH:D013088 Spermatocele Ethinyl Estradiol 9.0616709447
MESH:D013088 Spermatocele Tamoxifen 9.0616709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.3019457130
MESH:D013262 Stevens-Johnson Syndrome Phenytoin 4.4320235791
MESH:D013272 Stomach Diseases beta Carotene 8.1717638125
MESH:D013272 Stomach Diseases Dexamethasone 8.1715472012
MESH:D013274 Stomach Neoplasms arsenic trioxide 8.5017007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 8.5020155912 2093021
MESH:D013274 Stomach Neoplasms Cisplatin 8.5015958060 18396642 17522103
MESH:D013274 Stomach Neoplasms decitabine 8.5019037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 8.5018456281
MESH:D013274 Stomach Neoplasms Methylnitrosourea 8.5016257854 15930296 18593901
MESH:D013274 Stomach Neoplasms Tretinoin 8.5017261132
MESH:D013276 Stomach Ulcer beta Carotene 11.9212500499
MESH:D013276 Stomach Ulcer Curcumin 11.9216631530 19188055
MESH:D013276 Stomach Ulcer Dexamethasone 11.9215138204
MESH:D013276 Stomach Ulcer Melatonin 11.9211523592 16150113 12500499
MESH:D020521 Stroke Raloxifene 3.2216837676
MESH:D019966 Substance-Related Disorders bisphenol A 3.2516684133 16045194
MESH:D013736 Testicular Neoplasms Cisplatin 3.9417225452 15464296
MESH:D013921 Thrombocytopenia Lipopolysaccharides 7.9615821434
MESH:D013921 Thrombocytopenia vorinostat 7.9620479100
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.9311994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.5215669648
MESH:D013953 Thymus Neoplasms Methylnitrosourea 4.4911418001
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.1512697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 29.421399818 3712494 6587162 6582329 7505956
MESH:D013964 Thyroid Neoplasms arsenic trioxide 29.4219014326
MESH:D013964 Thyroid Neoplasms Butyrates 29.4217967635
MESH:D013964 Thyroid Neoplasms decitabine 29.4217967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 29.427505956
MESH:D013964 Thyroid Neoplasms Methylnitrosourea 29.423078959 7505956
MESH:D013964 Thyroid Neoplasms Retinoids 29.4216940797
MESH:D013964 Thyroid Neoplasms Tretinoin 29.4216026305 17045167
MESH:D013978 Tibial Fractures Estradiol 11.2119048282
MESH:D013978 Tibial Fractures Raloxifene 11.2119048282
MESH:D014062 Tongue Neoplasms Tretinoin 7.8116051514
MESH:D014062 Tongue Neoplasms Zinc 7.8116543248
MESH:D016171 Torsades de Pointes arsenic trioxide 3.2315213294
MESH:D014376 Tuberculosis Tretinoin 2.7216040207
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 25.848074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 25.8412845720 20435036 12973940 11780464
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 25.8417053015
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 25.8415464296 12973940 17225452
MESH:D001749 Urinary Bladder Neoplasms Curcumin 25.8418593936
MESH:D001749 Urinary Bladder Neoplasms decitabine 25.8419087683 17616700
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 25.8416720286
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 25.8417572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 25.8417572228 16712894 8653321
MESH:D014565 Urogenital Neoplasms Curcumin 4.5218462866
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 12.2516803524
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 12.2516154183
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 12.2516129372
MESH:D014591 Uterine Diseases bisphenol A 4.2514652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.6014692618
MESH:D014604 Uveal Neoplasms decitabine 10.3317785578
MESH:D014604 Uveal Neoplasms Tretinoin 10.3316752155
MESH:D014605 Uveitis Dexamethasone 4.061336536
MESH:D014625 Vaginal Neoplasms Cisplatin 3.8915577323
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.8412125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.4516837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.8714671159 15869587
MESH:D015837 Vestibular Diseases Gentamicins 4.8118776599
MESH:D014802 Vitamin A Deficiency Vitamin A 4.5916146918 16175781 16960172
MESH:D014820 Vitiligo Tretinoin 3.3516761959
MESH:D014839 Vomiting Cisplatin 3.9711897121
MESH:D014846 Vulvar Neoplasms Raloxifene 4.8016343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.4915886252
MESH:D009396 Wilms Tumor Tretinoin 3.3316287080
Pathway ID Pathway Name
KEGG:05221 Acute myeloid leukemia
KEGG:05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
KEGG:04514 Cell adhesion molecules (CAMs)
KEGG:05414 Dilated cardiomyopathy
KEGG:04512 ECM-receptor interaction
KEGG:04510 Focal adhesion
REACT:71 Gene Expression
KEGG:05410 Hypertrophic cardiomyopathy (HCM)
KEGG:04672 Intestinal immune network for IgA production
KEGG:05200 Pathways in cancer
KEGG:04810 Regulation of actin cytoskeleton
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA34225
    • No data
    Releated disease ID Related disease Name
    PA445062Neoplasms
    Releated drug ID Related drug Name
    PA451746tretinoin
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00210 agonist Adapalene Dermatologic Agents
    DB00459 agonist Acitretin Keratolytic Agents
    DB00523 agonist Alitretinoin Antineoplastic Agents;Keratolytic Agents
    DB00799 agonist Tazarotene Keratolytic Agents;Dermatologic Agents;Prodrugs;Teratogens
    DB00926 agonist Etretinate Keratolytic Agents
    DB00982 other/unknown Isotretinoin Antineoplastic Agents;Anti-acne Agents;Keratolytic Agents;Skin and Mucous Membrane Agents
    DB04942 binder Tamibarotene Anticancer Agents
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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