AutismKB 2.0

Annotation Detail for RBL1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RBL1 ( CP107,MGC40006,PRB1,p107 )
Gene Full Name: retinoblastoma-like 1 (p107)
Band: 20q11.23
Quick LinksEntrez ID:5933; OMIM: 116957; Uniprot ID:RBL1_HUMAN; ENSEMBL ID: ENSG00000080839; HGNC ID: 9893
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04350TGF-beta signaling pathway
hsa04110Cell cycle
No data
Pathway IDPathway Name
200171Validated targets of C-MYC transcriptional repression
200002Regulation of nuclear SMAD2/3 signaling
200027E2F transcription factor network
Pathway IDPathway Name
P04398p53 pathway feedback loops 2
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1831Prostate cancer
1944Breast cancer
1945Papillary cancer
2129Thyroid cancer
2137Adenoma of thyroid
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C028474 1,4-bis(2-(3,5-dichloropyridyloxy))benzene 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of RBL1 proteinincreases expression 15382178
C028474 1,4-bis(2-(3,5-dichloropyridyloxy))benzene 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased phosphorylation of RBL1 proteinincreases phosphorylation 12807759
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of RBL1 proteindecreases expression 15601625
C107875 6-(methylamino)pyrido(3,4-d)pyrimidine 6-(methylamino)pyrido(3,4-d)pyrimidine results in decreased expression of RBL1 proteindecreases expression 15572027
D000968 Antimycin A Antimycin A results in decreased expression of RBL1 mRNAdecreases expression 19304788
D001149 Arsenates [Atrazine co-treated with Arsenates] results in increased expression of RBL1 mRNAaffects cotreatment|increases expression 18585445
D001280 Atrazine [Atrazine co-treated with Arsenates] results in increased expression of RBL1 mRNAaffects cotreatment|increases expression 18585445
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RBL1 mRNAdecreases expression 20382639
C059041 calyculin A calyculin A inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RBL1 protein]decreases phosphorylation|decreases reaction 12621062
D002166 Camptothecin Camptothecin results in decreased expression of RBL1 proteindecreases expression 15585644
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of RBL1 mRNAincreases expression 19887370
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of RBL1 proteinincreases expression 19887370
C043867 cicaprost cicaprost results in decreased phosphorylation of RBL1 proteindecreases phosphorylation 12869629
D003513 Cycloheximide Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of RBL1 mRNA]decreases reaction|increases expression 11007951
D019259 Lamivudine [Zidovudine co-treated with Lamivudine] results in decreased expression of RBL1 mRNAaffects cotreatment|decreases expression 15784690
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of RBL1 mRNAincreases expression 17854601
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of RBL1 proteinincreases expression 19887370
17854601
D004052 Diethylnitrosamine RB1 protein affects the reaction [Diethylnitrosamine results in increased expression of RBL1 protein]affects reaction|increases expression 19887370
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of RBL1 mRNA]decreases reaction|increases expression 17854601
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of RBL1 protein]decreases reaction|increases expression 17854601
D004317 Doxorubicin Doxorubicin results in decreased expression of RBL1 proteindecreases expression 16537896
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of RBL1 mRNAaffects cotreatment|increases expression 17183730
D006861 Hydrogen Peroxide calyculin A inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RBL1 protein]decreases phosphorylation|decreases reaction 12621062
D006861 Hydrogen Peroxide Hydrogen Peroxide results in decreased phosphorylation of RBL1 proteindecreases phosphorylation 12621062
D006861 Hydrogen Peroxide Okadaic Acid inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RBL1 protein]decreases phosphorylation|decreases reaction 12621062
C051890 irinotecan irinotecan metabolite results in decreased expression of RBL1 mRNAdecreases expression 15956246
C051890 irinotecan irinotecan results in decreased expression of RBL1 mRNAdecreases expression 15956246
C013598 methoxyacetic acid methoxyacetic acid results in decreased phosphorylation of and results in decreased expression of RBL1 proteindecreases expression|decreases phosphorylation 11313878
D009151 Mustard Gas Mustard Gas results in increased expression of RBL1 mRNAincreases expression 15674843
D019319 Okadaic Acid Okadaic Acid inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RBL1 protein]decreases phosphorylation|decreases reaction 12621062
D010081 Oxazolone Oxazolone results in increased expression of RBL1 mRNAincreases expression 11379042
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of RBL1 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of RBL1 mRNAincreases expression 19482888
C006253 pirinixic acid pirinixic acid results in increased expression of RBL1 mRNAincreases expression 17950772
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of RBL1 mRNA]increases expression|increases reaction 17950772
D010936 Plant Extracts Plant Extracts results in decreased expression of RBL1 proteindecreases expression 15327971
D012402 Rotenone Rotenone results in decreased expression of RBL1 mRNAdecreases expression 19304788
C017947 sodium arsenite sodium arsenite results in increased expression of RBL1 mRNAincreases expression 16014739
D013629 Tamoxifen Tamoxifen results in increased phosphorylation of RBL1 proteinincreases phosphorylation 15642790
D013749 Tetrachlorodibenzodioxin Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of RBL1 mRNA]decreases reaction|increases expression 11007951
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of RBL1 mRNAincreases expression 11007951
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of RBL1 mRNAincreases expression 15667827
D014051 Toluene 2,4-Diisocyanate Toluene 2,4-Diisocyanate results in increased expression of RBL1 mRNAincreases expression 11379042
D014212 Tretinoin Tretinoin results in increased expression of RBL1 proteinincreases expression 15231690
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of RBL1 mRNAaffects cotreatment|increases expression 17183730
D015215 Zidovudine [Zidovudine co-treated with Lamivudine] results in decreased expression of RBL1 mRNAaffects cotreatment|decreases expression 15784690
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.2214745880
MESH:D000014 Abnormalities, Drug-Induced methoxyacetic acid 17.7112805644 15959878 1761404 1761407 3652986
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 17.716195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 17.7115322242 14514962 11752688
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 17.718875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.6419490988
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 4.519612607
MESH:D055371 Acute Lung Injury pirinixic acid 2.8218653653
MESH:D000230 Adenocarcinoma Doxorubicin 2.4917418594
MESH:D000236 Adenoma Diethylnitrosamine 2.6610737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 22.1718056438 19052882 17162532 19061943 17620307 16434500
MESH:D018248 Adenoma, Liver Cell Phenobarbital 22.1717620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 22.1716434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 22.1716835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.3715276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.5717306315 16712894
MESH:D000382 Agricultural Workers' Diseases Atrazine 3.9011874814
MESH:D000419 Albuminuria Doxorubicin 4.2321441931
MESH:D000505 Alopecia Tretinoin 3.3615955085
MESH:D000544 Alzheimer Disease Plant Extracts 2.9416962711
MESH:D000550 Amblyopia Valproic Acid 4.9017688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.6711748828
MESH:D001008 Anxiety Disorders Valproic Acid 3.3217497229
MESH:D001169 Arthritis, Experimental Plant Extracts 7.0114686799
MESH:D001169 Arthritis, Experimental Tretinoin 7.0116412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.1916292516
MESH:D001249 Asthma Mustard Gas 7.4510378619
MESH:D001249 Asthma Toluene 2,4-Diisocyanate 7.456091945 8156442 17015710 15590890 12762349 19187332 11077013 18394133 15855793 16210060 11742282 170078 15590891 7684630 11467998 3040596 16792590 12585506 10934080 20032816 10797510 12684321 6091946
MESH:D001249 Asthma Tretinoin 7.4516456186
MESH:D001321 Autistic Disorder Valproic Acid 2.0419232924 18316065 19460635 17157402 18396377 17507914 20603192 18985861 18940202 18558336 15238991 16609825 17688650 18177632 18775368
MESH:D001471 Barrett Esophagus Tretinoin 4.0916935849
MESH:D001714 Bipolar Disorder Valproic Acid 2.9117594078 20046352
MESH:D001768 Blister Mustard Gas 4.8319167455
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.5919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.5912125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 13.5916206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.3315746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.338888407
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.3714601052
MESH:D002545 Brain Ischemia Plant Extracts 4.4016041641
MESH:D001932 Brain Neoplasms Doxorubicin 3.5317150277
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.7917474063
MESH:D001943 Breast Neoplasms Doxorubicin 2.7915668708 15567936 15939500 15692762 15136595 16322301 11325840 16935488 16115903 16826403 17983394 15994142 16096432 18695136 17369602 17426702 19526202 15993339 18628466 18382427 18234424 15634643 16595493 16264153
MESH:D001943 Breast Neoplasms Tamoxifen 2.7919189212 18855134 21138602 11161223 16273361 16202921 20859285 19103187 19410462 20135344 19221464 19155303 21152245 19142967 19115204 15668708 19084267 20544844 16873071 18629630 20390343 18351453 18984771 19244106 16818667 15565566 17242785 19288272 19066611 17893378 20005174 19059307 19189210 18425577 20065188 17440819 18815881 19487384 19011961 17049068 18821012 18997820 19200415 19289846 17261762
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.7920435547
MESH:D001943 Breast Neoplasms Toluene 2,4-Diisocyanate 2.7911921183
MESH:D001943 Breast Neoplasms Tretinoin 2.7916443354 16166294 16873071
MESH:D016535 Bronchial Hyperreactivity Toluene 2,4-Diisocyanate 4.298156442 15590891 12507178
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.8315286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.6517687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.2616813970
MESH:D002057 Burns, Chemical Plant Extracts 5.009625245
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.4616097048 3786805 16227642 16011737 18705752 10355542 16192424 15673190 16050911 16124888 15700767 15721981
MESH:D002276 Carcinoid Tumor Doxorubicin 4.4816051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.5516835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.1919066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.8316168501
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 15.8918788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 15.8920512989 16502159 11831363 18978308 19052882 20214788 3084413 16830150 18971187 16878318 16807293 16935385 20007298 16540662 18494052 16698587 19394651 20727157 18210153 19701751 18785209 18788625 18691550 16569478 19539802 16288022 20432363 17173139 20935162 20514400 19418558 17978847 19335982 16328049 20101231 10672840 18665156 17138121 18056438 19171122 10737359 19919837 19822196 18506893 19107877 17761372 3581430 19208518 20524982 17055752 17428255 18393292 17162532 19519916 16681979 16779866 21159647 20084675 19383236
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 15.8918059187 17876044 16234567 16023760
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 15.8917173139 20007298 6705139 1701930 20935162
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 15.8918834353
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 15.8915276417 16507464 17306315
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 15.8916924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 15.891917145
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 3.0116201981 1485588
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 6.996189445
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 6.9918572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 6.9916051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.3317572228
MESH:D006332 Cardiomegaly Plant Extracts 6.3717645561
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.3716120746 18850075 18670907
MESH:D009202 Cardiomyopathies Doxorubicin 3.3216651473 15505089 16952015 17308081 16731534 16109756 16612575 17351982 16242529 17519947 17974986 17131338 17382496 17007740 15792986 17329180 15811867 15476868 16278810 18627295 16455267 16364871 17924179 17928571 16269455
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.8316243910 17334414
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 3.2916936243
MESH:D002386 Cataract Tretinoin 2.9017460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 9.9220889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 9.922727394 7505956 21159647 17174075
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 9.9220056578 19524636
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.934080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.2616129372
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.5920734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.4219052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.4216835633
MESH:D002779 Cholestasis pirinixic acid 2.5919176532
MESH:D002822 Choriocarcinoma Tretinoin 4.8316461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.3015340226 8697196 16354765 12621046 15668235
MESH:D002972 Cleft Palate Tretinoin 5.309407595
MESH:D003092 Colitis Tretinoin 3.3917035595
MESH:D003110 Colonic Neoplasms irinotecan 2.5417287894 17725105
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.7018802399 18259882
MESH:D015179 Colorectal Neoplasms irinotecan 2.7018259882 18509181 16391804 15273666 16303861 17159606 17454858
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7914669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.5415322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.548800419 9211117 16925845 14991402 17551590 9224671 10589399 9664655 9142499 9125849
MESH:D019465 Craniofacial Abnormalities Valproic Acid 3.5417688650 16575769 8888407
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0419031437
MESH:D017449 Dermatitis, Allergic Contact Toluene 2,4-Diisocyanate 3.8018759878 15491423 12956900
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2718249437
MESH:D003877 Dermatitis, Contact Oxazolone 9.1915944321 12811023
MESH:D003877 Dermatitis, Contact Toluene 2,4-Diisocyanate 9.1917010967
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 3.9320387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.9317107852
MESH:D003928 Diabetic Nephropathies Plant Extracts 8.3019706694
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.3019279558
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 10.9021278145 11566570 10915739 3786805 2869522 7120509 16177239 19085960 7440962 15968718 7179309 15998439 10092053 6623471 6884620 9327722 15027814 4309450 3732212 17522070 16227642 19336974
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 10.9019107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 10.9017416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 10.9020420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 10.901733752 19641884
MESH:D004362 Drug Toxicity Doxorubicin 17.7118602426
MESH:D004362 Drug Toxicity Lamivudine 17.7115040536
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 17.7111462148
MESH:D004362 Drug Toxicity Zidovudine 17.7115040536
MESH:D004421 Dystonia Phenobarbital 9.441851702
MESH:D004421 Dystonia Valproic Acid 9.441851702
MESH:D004487 Edema Mustard Gas 14.1011428647 11402378 11428631 9260866
MESH:D004487 Edema pirinixic acid 14.1012083418
MESH:D004487 Edema Plant Extracts 14.1012787963
MESH:D004487 Edema Tetrachlorodibenzodioxin 14.1011000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.8418230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 10.8418230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 3.2319031437
MESH:D016889 Endometrial Neoplasms Doxorubicin 11.2617359293
MESH:D016889 Endometrial Neoplasms Tamoxifen 11.2616202921 17893378 20544844 19155303
MESH:D016889 Endometrial Neoplasms Tretinoin 11.2616569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.749294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 12.9518037988
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 12.9515268973
MESH:D004802 Eosinophilia Toluene 2,4-Diisocyanate 4.348156442
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 9.733659116
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 9.733659116 17275665
MESH:D004828 Epilepsies, Partial Phenobarbital 8.873922381 11558140
MESH:D004828 Epilepsies, Partial Valproic Acid 8.8716628512 3922381
MESH:D004827 Epilepsy Phenobarbital 10.1420417680
MESH:D004827 Epilepsy Plant Extracts 10.1419700373 19439326
MESH:D004827 Epilepsy Valproic Acid 10.1418234410 20417680
MESH:D004832 Epilepsy, Absence Phenobarbital 7.966401628
MESH:D004832 Epilepsy, Absence Valproic Acid 7.967562514 6426943 6254150
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 10.247750514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 10.247750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 9.393659116
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 9.393659116
MESH:D004890 Erythema Mustard Gas 4.839357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.7916302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 1.9920426865
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.0411564622
MESH:D005124 Eye Abnormalities Tretinoin 8.049664655 16938888
MESH:D005128 Eye Diseases Toluene 2,4-Diisocyanate 5.4218447907
MESH:D005234 Fatty Liver Carbon Tetrachloride 32.5112631006 19224547 16045604 61145 15959796 17595544 12795759 16239168
MESH:D005234 Fatty Liver Diethylnitrosamine 32.5121071580 20387270
MESH:D005234 Fatty Liver pirinixic acid 32.5119236843 20131406
MESH:D005234 Fatty Liver Plant Extracts 32.5115975614
MESH:D005234 Fatty Liver Tamoxifen 32.5119224547 14986274
MESH:D005234 Fatty Liver Valproic Acid 32.5119224547 14986274
MESH:D005234 Fatty Liver Zidovudine 32.5118299183
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.0416709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1411858732
MESH:D005315 Fetal Diseases Valproic Acid 4.5616575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.828888407 18558336
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.2014745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 10.3519069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 10.3519069698
MESH:D005355 Fibrosis Carbon Tetrachloride 12.9218705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 12.9220067830
MESH:D005355 Fibrosis Tretinoin 12.9217994277
MESH:D005532 Foot Deformities, Congenital methoxyacetic acid 5.413652986
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.3516452187
MESH:D005909 Glioblastoma Doxorubicin 10.8917150277
MESH:D005909 Glioblastoma Okadaic Acid 10.8917312396
MESH:D005909 Glioblastoma Tretinoin 10.8917312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2610696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 7.1215692506
MESH:D006258 Head and Neck Neoplasms Tretinoin 7.1216096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.8316084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.9610048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 5.9614991402 9664655
MESH:D006331 Heart Diseases Doxorubicin 3.2616330681 16244372 12587719 16144979 18006777 18674790 17888722 16707910 16879835 16495754 14766674 17875725 16244371
MESH:D006333 Heart Failure Doxorubicin 10.7517481944
MESH:D006333 Heart Failure pirinixic acid 10.7520558911
MESH:D006333 Heart Failure Plant Extracts 10.7518097624
MESH:D006394 Hemangiosarcoma Doxorubicin 3.6115692506
MESH:D006402 Hematologic Diseases Zidovudine 4.4112579204
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0511000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.2919900420 19110552
MESH:D006509 Hepatitis B Lamivudine 4.8117703166
MESH:D019694 Hepatitis B, Chronic Lamivudine 4.8115309715 15631357 16476009 15274664 12044531
MESH:D006529 Hepatomegaly 1,4-bis(2-(3,5-dichloropyridyloxy))benzene 18.1116109766
MESH:D006529 Hepatomegaly Phenobarbital 18.1116109766
MESH:D006529 Hepatomegaly pirinixic acid 18.1119772884 16221962 18467677 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 18.1112621046 15340226 16120746
MESH:D006561 Herpes Simplex Plant Extracts 4.3010715843
MESH:D015658 HIV Infections Lamivudine 10.049296927 20032539 17530837 11141242
MESH:D015658 HIV Infections Plant Extracts 10.0412878215
MESH:D015658 HIV Infections Zidovudine 10.0411698656 17358032 20032539 11363243 11141242
MESH:D006689 Hodgkin Disease Doxorubicin 6.5817606976 18501091 15147373
MESH:D006689 Hodgkin Disease sodium arsenite 6.5812676792
MESH:D019584 Hot Flashes Plant Extracts 4.4214716179 16566672 17454163
MESH:D006849 Hydrocephalus Valproic Acid 4.5417688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.718697196 15340226 16959395 18606429 16354765
MESH:D006930 Hyperalgesia Tretinoin 2.9616870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.2116899240
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2516778211
MESH:D006943 Hyperglycemia pirinixic acid 2.9020558911
MESH:D020138 Hyperhomocysteinemia Plant Extracts 4.1916484555
MESH:D006949 Hyperlipidemias Plant Extracts 4.1715268973 15975614
MESH:D006967 Hypersensitivity Toluene 2,4-Diisocyanate 4.3210880147 11019492
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.7818850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.7715338365
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.3116612254
MESH:D007248 Infertility, Male Atrazine 6.3712948887
MESH:D007248 Infertility, Male sodium arsenite 6.3712646999 15346721
MESH:D007249 Inflammation Diethylnitrosamine 14.0418785209
MESH:D007249 Inflammation Mustard Gas 14.049357497 11428620 11402378 9260866 11428647 8975870 16001271 17524151 11428631
MESH:D007249 Inflammation Plant Extracts 14.0419332304 12787963 16366677 15997105
MESH:D007249 Inflammation Tamoxifen 14.0419457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 14.0412878042 12200463
MESH:D007333 Insulin Resistance pirinixic acid 2.4216306350
MESH:D007410 Intestinal Diseases Tretinoin 3.4517994277
MESH:D007414 Intestinal Neoplasms Plant Extracts 4.3412351151 12584176 12628509
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.9716580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.9715992940 17551590
MESH:D007674 Kidney Diseases Doxorubicin 5.6515699352 15369732 16775033
MESH:D007674 Kidney Diseases sodium arsenite 5.6520008137
MESH:D007676 Kidney Failure, Chronic Doxorubicin 9.1616707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 9.1616518626
MESH:D007680 Kidney Neoplasms Tamoxifen 6.8218625569
MESH:D007680 Kidney Neoplasms Zidovudine 6.8212579204
MESH:D007938 Leukemia 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 6.1512970779
MESH:D007938 Leukemia Tretinoin 6.1517143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.8316085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 4.1220370541
MESH:D007951 Leukemia, Myeloid Tretinoin 3.4119285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.6719850784 17596541 16294345
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 3.6717596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.9419035177 19225113 17217047 19075265 17339181 12679006 17649720 17506722 16331271 16788101 16891316 17368321 15748426 17301526 17107899 19029980 17712046 16935935 17294898 16140955 17361223 16823087 16766008 9834237 19642359
MESH:D017880 Limb Deformities, Congenital methoxyacetic acid 7.8915959878 12805644
MESH:D017880 Limb Deformities, Congenital Tretinoin 7.899224671
MESH:D008064 Lipidoses Tamoxifen 2.9317567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 14.3016221502 16943688 11408273 11903743 17334410 16239168 17174718 17157831 21278145
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 14.3018665156 20032147 18522880 19638242 18407596
MESH:D008103 Liver Cirrhosis Phenobarbital 14.3021047994
MESH:D008103 Liver Cirrhosis Plant Extracts 14.3017157831
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 10.2216638106 15876570 18187930 15893842 15925388 12445421 12649538 17565644 18251166 18481824 12445418 16033810 15362042 17525996 17714472 13678700 17698563 16015684 17766677 17944888 15818738 18429990 18395914 14716496 16192424 14748882 17805973 14716833 17631135 16027843 18412020 12609069 15338365 18205269 12389079 18263696 12632512 17823541 12741479 17900296 14512876 18418968 15370692 16097048 12958196 15052691 18339082 16011737 17708605 17640975 18210741 18279442 18472094 18277467 15673190 10355542 18376398 18395095 16248980 12667390 12586293 18420326 16136751 18472332 18054572 15057751 15730626 11481614 17869086 18317297 12546737 18156304 17481882 12666154 15123356 16116963 17922224 18166357 12632514 17721639 12898905 15650968 15996030 20821823 18006644 15959796 14620537 18705752 17761835 14724832 17557913 17976157 15931870
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 10.2216595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 10.2215474484
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 10.2215479170
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 10.2218564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 10.2212878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 10.2216248980 18397230
MESH:D008107 Liver Diseases Carbon Tetrachloride 8.6715720792 16246199 15830285 16964402 17285989
MESH:D008107 Liver Diseases Diethylnitrosamine 8.6717034775
MESH:D008107 Liver Diseases Phenobarbital 8.6719363144
MESH:D008107 Liver Diseases Plant Extracts 8.6717034775
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8515123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.4116899240 14706259
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 23.6819294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 23.682422723 19426721 20501860 21071580 19690152 19638242 19427195 21278145 20492335 20101389 15885732 15175105 21047994 18648771 10737359 20452335 16942905 20118626 20434301 19294768 19850985 19642983 19256749 19255062 18644402 18978307 19833225 19499222 19073162 12771043 19090486 20137499 19551842 18977376 9163691 19254457 20405173 19996281 18754104 12112319 19812893 2862719 21167192 20583210
MESH:D008113 Liver Neoplasms Phenobarbital 23.688742319 19812893 19482888 19073162 15975961 21047994
MESH:D008113 Liver Neoplasms pirinixic acid 23.6820007298 15890375 16377806
MESH:D008113 Liver Neoplasms Plant Extracts 23.6819168119
MESH:D008113 Liver Neoplasms sodium arsenite 23.6815276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 23.6816684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 23.6816984957
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 16.4812014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 16.4818164116 16842330 2563599 9362446 17942915 19009564 18253720 21159647 18093689 18308698 17854601 18079962 17174075 16267830 19126423 19539802 3124819 18775883 19004024 18544905 18282651 19519916
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 16.4817085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 16.4818308698 6150874 17172636 2563599 1399818
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 16.4812151625
MESH:D008171 Lung Diseases Mustard Gas 6.8218161513 18702808
MESH:D008171 Lung Diseases sodium arsenite 6.8219095001
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 3.9317228818
MESH:D008175 Lung Neoplasms Diethylnitrosamine 12.2020970405 6695378 20512841 21163286
MESH:D008175 Lung Neoplasms Doxorubicin 12.206189445 17418594
MESH:D008175 Lung Neoplasms Mustard Gas 12.203148597 8781369
MESH:D008175 Lung Neoplasms Plant Extracts 12.2020869020
MESH:D008175 Lung Neoplasms sodium arsenite 12.2017306315 15276417 19931552 17077188 16712894
MESH:D008175 Lung Neoplasms Tamoxifen 12.2018625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 12.2011884234 19555203
MESH:D008175 Lung Neoplasms Zidovudine 12.2018800350
MESH:D008223 Lymphoma Doxorubicin 3.2316098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.5317654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.2515621674
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.4419428831
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 5.4515458769
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 5.4511731420 14580682 16827153 19196723 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 4.2219453300
MESH:D008527 Medulloblastoma Tretinoin 2.6517453147
MESH:D008545 Melanoma Doxorubicin 6.7716827129
MESH:D008545 Melanoma sodium arsenite 6.7716487513 19082730
MESH:D008545 Melanoma Tamoxifen 6.7712393984 19393235
MESH:D008545 Melanoma Tretinoin 6.7716752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.8615990972
MESH:D008591 Meningomyelocele Tretinoin 4.1116940565
MESH:D008654 Mesothelioma Atrazine 6.111916698
MESH:D008654 Mesothelioma Doxorubicin 6.1117638057
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 5.5117358032
MESH:D008881 Migraine Disorders Valproic Acid 2.9618765137 18803445
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.2115792986
MESH:D052016 Mucositis Doxorubicin 11.3317415656
MESH:D052016 Mucositis irinotecan 11.3317159606
MESH:D009135 Muscular Diseases pirinixic acid 3.1916239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.748888407
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.7717596541
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 6.7717596541
MESH:D009203 Myocardial Infarction Doxorubicin 5.2419429709 15857846
MESH:D009203 Myocardial Infarction pirinixic acid 5.2419151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.7612213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.7016411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.1517484760
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 12.509029167 3581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 12.5018259882
MESH:D009362 Neoplasm Metastasis irinotecan 12.5018259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 12.5019393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4119410462
MESH:D009369 Neoplasms pirinixic acid 7.2817405874
MESH:D009369 Neoplasms sodium arsenite 7.2811559025
MESH:D009369 Neoplasms Tretinoin 7.2816946489 16594593
MESH:D009374 Neoplasms, Experimental sodium arsenite 8.4420056578
MESH:D009374 Neoplasms, Experimental Toluene 2,4-Diisocyanate 8.441670384
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.6719200415 19189210 19196722
MESH:D009401 Nephrosis Doxorubicin 4.4516899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.7315640375 16889571
MESH:D009410 Nerve Degeneration Rotenone 3.6315790535 18619942 17356569
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.4814600291
MESH:D009421 Nervous System Malformations Tretinoin 8.489125849
MESH:D009436 Neural Tube Defects sodium arsenite 10.9312854658
MESH:D009436 Neural Tube Defects Tretinoin 10.939142499
MESH:D009436 Neural Tube Defects Valproic Acid 10.938888407 16359493
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 4.8617168769
MESH:D009447 Neuroblastoma Doxorubicin 6.5915555623
MESH:D009447 Neuroblastoma irinotecan 6.598761367
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.0820387270
MESH:D017599 Neuroectodermal Tumors irinotecan 4.408761367
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.7920387270
MESH:D009503 Neutropenia Mustard Gas 3.6716761898 7688884
MESH:D009765 Obesity pirinixic acid 4.4620558911
MESH:D009765 Obesity Plant Extracts 4.4619056576 20132043
MESH:D009784 Occupational Diseases Toluene 2,4-Diisocyanate 4.4411077013 18394133 12585506 3040596 6091945 8156442 6091946
MESH:D010018 Osteomalacia Phenobarbital 4.0417016548
MESH:D012516 Osteosarcoma Doxorubicin 3.8615930896
MESH:D010051 Ovarian Neoplasms 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 7.3916211241
MESH:D010051 Ovarian Neoplasms sodium arsenite 7.3915276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 7.3916936753
MESH:D010146 Pain Tretinoin 2.6516870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 7.8916540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 7.8916965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 7.8915976015
MESH:D010212 Papilloma Hydrogen Peroxide 8.6312065085
MESH:D010212 Papilloma Plant Extracts 8.6315173996 16517061
MESH:D010300 Parkinson Disease Atrazine 5.3317218051
MESH:D010300 Parkinson Disease Rotenone 5.3311535288 16412576 18191903 16140633 15451049 18619942 11445065 19232380 19114014
MESH:D020734 Parkinsonian Disorders Rotenone 3.8018197244 15927086 15574749 15795934
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9212520081
MESH:D003557 Phyllodes Tumor Doxorubicin 4.8317983394
MESH:D010997 Pleural Neoplasms Doxorubicin 4.8317638057
MESH:D011041 Poisoning Mustard Gas 3.5015727166
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2518163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.192563599
MESH:D011230 Precancerous Conditions Phenobarbital 8.192563599
MESH:D011225 Pre-Eclampsia cicaprost 5.6310329876
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.3811222880 11118676 11399792 11896295
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 8.3820603192
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.1915749863 16729912 16888761 18437689 16868541 15897917
MESH:D011471 Prostatic Neoplasms Plant Extracts 2.1914666653 17804756
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.1916039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.1915067354
MESH:D011507 Proteinuria Tretinoin 3.3116636307
MESH:D011537 Pruritus Mustard Gas 3.7718058305
MESH:D019310 Pseudolymphoma Phenobarbital 11.0812752131
MESH:D019310 Pseudolymphoma Valproic Acid 11.0812752131 11422049
MESH:D011625 Pterygium Tretinoin 4.4716723453
MESH:D011657 Pulmonary Eosinophilia Toluene 2,4-Diisocyanate 5.2914606601
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.8017266442 10334151 17894541 17720292 17620002
MESH:D051437 Renal Insufficiency Doxorubicin 3.9017922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.2319058328
MESH:D012130 Respiratory Hypersensitivity Toluene 2,4-Diisocyanate 4.2220219652 16940033 7692837
MESH:D012135 Respiratory Sounds Atrazine 4.2011874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5318990726
MESH:D012140 Respiratory Tract Diseases Toluene 2,4-Diisocyanate 4.7918447907
MESH:D012206 Rhabdomyolysis Lamivudine 5.219296927
MESH:D012208 Rhabdomyosarcoma Tretinoin 9.8616283617 16116481
MESH:D012208 Rhabdomyosarcoma Valproic Acid 9.8619155313
MESH:D012220 Rhinitis Toluene 2,4-Diisocyanate 4.3019050374
MESH:D012221 Rhinitis, Allergic, Perennial Toluene 2,4-Diisocyanate 4.9512617775 15015336
MESH:D006255 Rhinitis, Allergic, Seasonal Toluene 2,4-Diisocyanate 5.1819075512
MESH:D012509 Sarcoma Doxorubicin 3.7115625365 17203757 16767912 17710206 18313854 15675481
MESH:D012512 Sarcoma, Ewing's Doxorubicin 3.9316326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.4617846226
MESH:D012559 Schizophrenia Valproic Acid 2.0319110320 15737665
MESH:D012640 Seizures Phenobarbital 5.273137016 11442880 4039156 16876388
MESH:D012640 Seizures Valproic Acid 5.271511512 16876388 11044598 14763951 11738929 17978042 3137016 15475178
MESH:D003294 Seizures, Febrile Phenobarbital 4.506407741
MESH:D012871 Skin Diseases Mustard Gas 2.6316961503 15451306 12880345
MESH:D012878 Skin Neoplasms Doxorubicin 24.8115692506
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 24.8112065085
MESH:D012878 Skin Neoplasms Okadaic Acid 24.8112628509
MESH:D012878 Skin Neoplasms Plant Extracts 24.8115173996 16517061
MESH:D012878 Skin Neoplasms sodium arsenite 24.8119524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 24.8116192470
MESH:D012878 Skin Neoplasms Tretinoin 24.8116467112
MESH:D012912 Sneezing Toluene 2,4-Diisocyanate 5.1819075512 19050374
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.2517203757 16767912 15625365
MESH:D013088 Spermatocele Tamoxifen 3.9616709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.7119457130
MESH:D016135 Spinal Dysraphism sodium arsenite 8.7212854658
MESH:D016135 Spinal Dysraphism Valproic Acid 8.7219490988
MESH:D013226 Status Epilepticus Valproic Acid 4.2112833885
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 4.4818456281
MESH:D013274 Stomach Neoplasms irinotecan 4.4815723263
MESH:D013274 Stomach Neoplasms Tretinoin 4.4817261132
MESH:D013274 Stomach Neoplasms Zidovudine 4.4817696246
MESH:D013276 Stomach Ulcer Plant Extracts 3.6117135157 12787963 15255614 18237397 18193104
MESH:D013576 Syndactyly methoxyacetic acid 5.321761404 1761407
MESH:D024801 Tauopathies Camptothecin 5.3016930453
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 5.1517997062
MESH:D013733 Testicular Diseases methoxyacetic acid 5.016499806 18486176
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5712697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 15.107505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 15.1017909728 16010429
MESH:D013964 Thyroid Neoplasms Phenobarbital 15.101399818
MESH:D013964 Thyroid Neoplasms Tretinoin 15.1016026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 3.5116051514
MESH:D014178 Translocation, Genetic Valproic Acid 4.9017262798
MESH:D014376 Tuberculosis Tretinoin 3.0316040207
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.193119515
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 7.6117653716
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 7.6117306315 11723127 16712894 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 7.6116712894 17572228 8653321
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.328888407
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 8.4811813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.4816129372
MESH:D014604 Uveal Neoplasms Tretinoin 4.2816752155
MESH:D014625 Vaginal Neoplasms Zidovudine 4.4412579204
MESH:D014652 Vascular Diseases sodium arsenite 4.1017056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2612125929
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 9.4417678736 16364871 17334414 17638931
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 9.4418097624
MESH:D020257 Ventricular Remodeling Plant Extracts 4.9918097624
MESH:D014820 Vitiligo Tretinoin 3.7516761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9215886252
MESH:D009396 Wilms Tumor Tretinoin 3.6916287080
MESH:D014947 Wounds and Injuries Plant Extracts 3.9920213670 19894650
Pathway ID Pathway Name
KEGG:04110 Cell cycle
KEGG:04350 TGF-beta signaling pathway
Pharmacogenomics Knowledge Base Top
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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