AutismKB 2.0

Annotation Detail for RBL2


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Basic Information Top
Gene Symbol:RBL2 ( FLJ26459,P130,Rb2 )
Gene Full Name: retinoblastoma-like 2 (p130)
Band: 16q12.2
Quick LinksEntrez ID:5934; OMIM: 180203; Uniprot ID:RBL2_HUMAN; ENSEMBL ID: ENSG00000103479; HGNC ID: 9894
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04350TGF-beta signaling pathway
hsa04110Cell cycle
No data
Pathway IDPathway Name
200027E2F transcription factor network
200091FoxO family signaling
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of RBL2 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of RBL2 mRNAaffects expression 21346803
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of RBL2 mRNAincreases expression 16788091
C026137 3-hydroxyacetanilide 3-hydroxyacetanilide results in decreased expression of RBL2 mRNAdecreases expression 18544908
C027576 4-hydroxy-2-nonenal 4-hydroxy-2-nonenal results in decreased expression of RBL2 mRNAdecreases expression 12419474
C107875 6-(methylamino)pyrido(3,4-d)pyrimidine 6-(methylamino)pyrido(3,4-d)pyrimidine results in increased expression of RBL2 proteinincreases expression 15572027
D000082 Acetaminophen Acetaminophen results in decreased expression of RBL2 mRNAdecreases expression 18544908
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RBL2 mRNAaffects expression 16483693
D001149 Arsenates [Atrazine co-treated with Arsenates] results in increased expression of RBL2 mRNAaffects cotreatment|increases expression 18585445
D001280 Atrazine [Atrazine co-treated with Arsenates] results in increased expression of RBL2 mRNAaffects cotreatment|increases expression 18585445
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of RBL2 mRNAdecreases expression 12419474
D002087 Butyrates Butyrates results in decreased expression of RBL2 mRNAdecreases expression 14674679
C031938 calmidazolium calmidazolium results in decreased phosphorylation of RBL2 proteindecreases phosphorylation 15708436
C059041 calyculin A calyculin A inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RBL2 protein]decreases phosphorylation|decreases reaction 12621062
D002166 Camptothecin RBL2 protein inhibits the reaction [Camptothecin results in increased cleavage of PARP1 protein]decreases reaction|increases cleavage 15585644
D002166 Camptothecin RBL2 protein results in decreased susceptibility to Camptothecindecreases response to substance 15585644
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of RBL2 proteindecreases expression 19887370
C099555 CD 437 CD 437 results in increased expression of RBL2 proteinincreases expression 15059897
C098869 clasto-lactacystin beta-lactone clasto-lactacystin beta-lactone results in increased expression of RBL2 proteinincreases expression 16936753
D016572 Cyclosporine Cyclosporine results in decreased expression of RBL2 mRNAdecreases expression 20106945
D019259 Lamivudine [Zidovudine co-treated with Lamivudine] results in decreased expression of RBL2 mRNAaffects cotreatment|decreases expression 15784690
D004041 Dietary Fats Dietary Fats results in decreased expression of RBL2 mRNAdecreases expression 18042831
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of RBL2 proteinincreases expression 19887370
D002117 Calcitriol Calcitriol results in increased expression of RBL2 mRNAincreases expression 14729647
D004112 Dimercaprol Dimercaprol inhibits the reaction [Mustard Gas results in decreased expression of RBL2 mRNA]decreases expression|decreases reaction 16377760
D004317 Doxorubicin Doxorubicin promotes the reaction [RBL2 protein binds to CCNA2 promoter]affects binding|increases reaction 16537896
D004317 Doxorubicin Doxorubicin promotes the reaction [RBL2 protein binds to CCNB1 promoter]affects binding|increases reaction 16537896
D004317 Doxorubicin Doxorubicin promotes the reaction [RBL2 protein binds to CDK1 promoter]affects binding|increases reaction 16537896
D004317 Doxorubicin Doxorubicin promotes the reaction [RBL2 protein binds to PCNA promoter]affects binding|increases reaction 16537896
D004317 Doxorubicin Doxorubicin results in increased expression of RBL2 proteinincreases expression 16537896
D004317 Doxorubicin RBL2 protein inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]decreases reaction|increases cleavage 15585644
D004317 Doxorubicin RBL2 protein inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15585644
D004317 Doxorubicin RBL2 protein results in decreased susceptibility to Doxorubicindecreases response to substance 15585644
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of RBL2 mRNAaffects cotreatment|increases expression 19619570
D004958 Estradiol Estradiol results in decreased expression of RBL2 mRNAdecreases expression 19619570
D005419 Flavonoids Flavonoids results in decreased expression of RBL2 mRNAdecreases expression 18035473
C040313 fostriecin fostriecin results in increased phosphorylation of RBL2 proteinincreases phosphorylation 16936753
C096856 FTI 277 [Tamoxifen co-treated with FTI 277] results in decreased phosphorylation of RBL2 proteinaffects cotreatment|decreases phosphorylation 12866041
D017313 Fenretinide Fenretinide results in increased expression of RBL2 proteinincreases expression 15059897
D006861 Hydrogen Peroxide calyculin A inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RBL2 protein]decreases phosphorylation|decreases reaction 12621062
D006861 Hydrogen Peroxide Hydrogen Peroxide results in decreased expression of RBL2 mRNAdecreases expression 12419474
D006861 Hydrogen Peroxide Hydrogen Peroxide results in decreased phosphorylation of RBL2 proteindecreases phosphorylation 12621062
D006861 Hydrogen Peroxide Okadaic Acid inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RBL2 protein]decreases phosphorylation|decreases reaction 12621062
D009151 Mustard Gas Dimercaprol inhibits the reaction [Mustard Gas results in decreased expression of RBL2 mRNA]decreases expression|decreases reaction 16377760
D009151 Mustard Gas Mustard Gas results in decreased expression of RBL2 mRNAdecreases expression 16377760
D009151 Mustard Gas Mustard Gas results in increased expression of RBL2 mRNAincreases expression 15674843
D019319 Okadaic Acid Okadaic Acid inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RBL2 protein]decreases phosphorylation|decreases reaction 12621062
D019319 Okadaic Acid Okadaic Acid results in increased phosphorylation of RBL2 proteinincreases phosphorylation 16936753
D010126 Ozone Ozone results in decreased expression of RBL2 mRNAdecreases expression 16330353
C041786 palm oil palm oil results in decreased expression of RBL2 mRNAdecreases expression 18042831
C035988 procymidone procymidone results in increased expression of RBL2 mRNAincreases expression 15686871
C017947 sodium arsenite sodium arsenite affects the expression of RBL2 mRNAaffects expression 19822182
D013629 Tamoxifen [Tamoxifen co-treated with FTI 277] results in decreased phosphorylation of RBL2 proteinaffects cotreatment|decreases phosphorylation 12866041
C004648 testosterone enanthate testosterone enanthate affects the expression of RBL2 mRNAaffects expression 17440010
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of RBL2 mRNAaffects cotreatment|increases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of RBL2 mRNAdecreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of RBL2 mRNAincreases expression 16102516
D014212 Tretinoin RBL2 protein affects the susceptibility to Tretinoinaffects response to substance 16206244
D014212 Tretinoin Tretinoin promotes the reaction [PPP2CA protein binds to RBL2 protein]affects binding|increases reaction 16206244
D014212 Tretinoin Tretinoin results in decreased ubiquitination of RBL2 proteindecreases ubiquitination 16936753
D014212 Tretinoin Tretinoin results in increased expression of RBL2 proteinincreases expression 15059897
D014212 Tretinoin Tretinoin promotes the reaction [PPP2CA protein binds to and results in decreased phosphorylation of RBL2 protein]affects binding|decreases phosphorylation|increases reaction 16936753
D014212 Tretinoin Tretinoin results in increased stability of and results in increased expression of RBL2 proteinincreases expression|increases stability 16936753
D015215 Zidovudine [Zidovudine co-treated with Lamivudine] results in decreased expression of RBL2 mRNAaffects cotreatment|decreases expression 15784690
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.1014745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.4111752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.1218287403
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 4.399612607
MESH:D000230 Adenocarcinoma Doxorubicin 6.4917418594
MESH:D000230 Adenocarcinoma Estradiol 6.4911473722
MESH:D000230 Adenocarcinoma Fenretinide 6.4910697514
MESH:D000236 Adenoma Diethylnitrosamine 2.5910737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 8.5816434500 19061943 17162532 17620307 18056438 19052882
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.5816835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.2515276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.4516712894 17306315
MESH:D000382 Agricultural Workers' Diseases Atrazine 3.7911874814
MESH:D000419 Albuminuria Doxorubicin 4.1221441931
MESH:D000505 Alopecia Tretinoin 3.2615955085
MESH:D000544 Alzheimer Disease Ozone 2.3415513908
MESH:D000690 Amyotrophic Lateral Sclerosis 4-hydroxy-2-nonenal 3.8210965797
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.5711748828
MESH:D000799 Angioedema Acetaminophen 3.3910982225
MESH:D001161 Arteriosclerosis Dietary Fats 3.4615238619
MESH:D001169 Arthritis, Experimental Tretinoin 2.8016412693
MESH:D001172 Arthritis, Rheumatoid Ozone 4.2615570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.2616292516
MESH:D001249 Asthma Mustard Gas 7.0510378619
MESH:D001249 Asthma Ozone 7.0517854713 16373670
MESH:D001249 Asthma Tretinoin 7.0516456186
MESH:D001321 Autistic Disorder Acetaminophen 1.4718445737
MESH:D001471 Barrett Esophagus Tretinoin 3.9816935849
MESH:D001768 Blister Mustard Gas 4.7219167455
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 7.6312125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 7.6316206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3415340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4715746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.2514601052
MESH:D001932 Brain Neoplasms Doxorubicin 7.8517150277
MESH:D001932 Brain Neoplasms Fenretinide 7.8516187019
MESH:D001943 Breast Neoplasms Calcitriol 5.3011237771
MESH:D001943 Breast Neoplasms Dietary Fats 5.3020435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 5.3017474063
MESH:D001943 Breast Neoplasms Doxorubicin 5.3015993339 16595493 16264153 17369602 15136595 15634643 16096432 15668708 19526202 18628466 16826403 17983394 15692762 17426702 16322301 18234424 18382427 15567936 15994142 11325840 15939500 16115903 18695136 16935488
MESH:D001943 Breast Neoplasms Estradiol 5.3012948864 17261762 17289903 19861407 16675129 18497071 14630087 17018787
MESH:D001943 Breast Neoplasms Fenretinide 5.3016601279
MESH:D001943 Breast Neoplasms Tamoxifen 5.3019244106 18855134 19410462 16873071 18629630 17893378 18425577 21152245 20065188 18815881 11161223 18351453 17049068 17440819 19487384 19200415 16273361 19189212 17242785 19115204 16818667 19221464 19059307 19142967 17261762 19011961 19288272 16202921 19289846 19189210 21138602 19084267 18997820 15565566 20135344 20544844 19066611 15668708 20390343 19103187 19155303 18984771 20005174 20859285 18821012
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.3020435547
MESH:D001943 Breast Neoplasms Tretinoin 5.3016873071 16443354 16166294
MESH:D016535 Bronchial Hyperreactivity Ozone 3.3314754758 18315731 17626835 15516495 16777450 18417511 19059883
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.7215286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.5310378619 17687719
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.1516813970
MESH:D002100 Cachexia Ozone 4.3016183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0216111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.3518705752 16227642 16097048 15673190 10355542 16192424 16011737 15700767 16124888 3786805 15721981 16050911
MESH:D002276 Carcinoid Tumor Doxorubicin 4.3616051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.4516835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.0719066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.7116168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 24.0516705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 24.0516705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 24.053084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 24.0518788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 24.0516681979 17138121 16807293 20514400 19394651 20727157 18494052 19052882 18785209 19539802 20935162 3084413 16540662 16288022 16830150 11831363 20101231 18506893 17428255 21159647 10737359 18210153 19418558 16502159 18056438 20524982 10672840 16328049 19919837 17173139 19208518 17978847 3581430 16779866 18665156 16878318 19335982 18393292 19519916 19822196 19107877 16569478 18978308 17761372 20432363 19701751 16698587 20214788 18691550 19171122 17055752 16935385 20084675 18788625 18971187 20007298 20512989 19383236 17162532
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 24.0516234567 17876044 18059187 16023760
MESH:D006528 Carcinoma, Hepatocellular Estradiol 24.0516924424
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 24.0516270382 17159502
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 24.0517306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 24.0516924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 24.051917145
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 2.9416201981 1485588
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 12.7711237771
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 12.776189445
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 12.7716274795
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 12.7718572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 12.7716051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.2317572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.1118850075 18670907 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 3.2316364871 17924179 17007740 17974986 15792986 16269455 16952015 15476868 16278810 16651473 16612575 17519947 17382496 15505089 17131338 16731534 15811867 17928571 16242529 17351982 17329180 16109756 16455267 18627295 17308081
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.7817334414 16243910
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 3.2116936243
MESH:D002386 Cataract Acetaminophen 6.3310977129
MESH:D002386 Cataract Tretinoin 6.3317460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 17.816135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 17.8112371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 17.8117174075 7505956 2727394 21159647
MESH:D002471 Cell Transformation, Neoplastic Estradiol 17.8118566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 17.8119524636 20056578
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 11.5016154183
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 11.5016129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.0919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.0916835633
MESH:D002779 Cholestasis Cyclosporine 2.5919486331
MESH:D002822 Choriocarcinoma Tretinoin 4.7116461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.1012621046 8697196 15668235 16354765 15340226
MESH:D002972 Cleft Palate Tretinoin 5.109407595
MESH:D003092 Colitis Tretinoin 3.2817035595
MESH:D003110 Colonic Neoplasms Butyrates 3.0015936596
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.7818802399 18259882
MESH:D015179 Colorectal Neoplasms Fenretinide 2.7817273769
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.6917141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.2920055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.299142499 16925845 8800419 17551590 10589399 9211117 9664655 14991402 9125849 9224671
MESH:D003490 Cyanosis 2,4-dinitrotoluene 9.4618551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 9.4618551238
MESH:D003711 Demyelinating Diseases Tamoxifen 3.9319031437
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 3.8020387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.8017107852
MESH:D003928 Diabetic Nephropathies Estradiol 7.6119279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 7.6119279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 16.3418551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 16.3421346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 16.3411739529 18071297 16393943 17906064 11743745 16781746 15968718 19739265 11421492 11461765 12540782 14725611 17522070 10915739 19923254 16109766 19085960 18713872 2444490 19416960 19164858 12705907 12594235 16177239 15619225 11287661 17562736 10663392 14986274 12153990 14550746 16081117 11529661 19420014 16227642 19370779 16485898 11834606 12392966 12958197 10774834
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 16.342869522 7179309 11566570 6623471 16227642 10915739 16177239 6884620 7440962 10092053 17522070 21278145 9327722 3732212 15968718 19336974 19085960 15027814 4309450 7120509 15998439 3786805
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 16.3419107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 16.3417416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 16.3420420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6519426721
MESH:D004362 Drug Toxicity Doxorubicin 16.9618602426
MESH:D004362 Drug Toxicity Lamivudine 16.9615040536
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 16.9611462148
MESH:D004362 Drug Toxicity Zidovudine 16.9615040536
MESH:D050171 Dyslipidemias Dietary Fats 3.1318367378
MESH:D004487 Edema Mustard Gas 5.5611402378 9260866 11428631 11428647
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.5611000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.4418230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 10.4418230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 7.8315138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 7.8319031437
MESH:D016889 Endometrial Neoplasms Doxorubicin 15.3517359293
MESH:D016889 Endometrial Neoplasms Estradiol 15.3519148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Tamoxifen 15.3519155303 20544844 16202921 17893378
MESH:D016889 Endometrial Neoplasms Tretinoin 15.3516569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.649294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.7018037988
MESH:D004890 Erythema Mustard Gas 4.729357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6616302075
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.7311564622
MESH:D005124 Eye Abnormalities Tretinoin 7.739664655 16938888
MESH:D005234 Fatty Liver Carbon Tetrachloride 25.6016045604 12631006 61145 15959796 19224547 17595544 12795759 16239168
MESH:D005234 Fatty Liver Cyclosporine 25.6019224547
MESH:D005234 Fatty Liver Dietary Fats 25.6019551842 18296743 19004024 17967931
MESH:D005234 Fatty Liver Diethylnitrosamine 25.6021071580 20387270
MESH:D005234 Fatty Liver Tamoxifen 25.6019224547 14986274
MESH:D005234 Fatty Liver Zidovudine 25.6018299183
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.9616709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0211858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.0814745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 9.9719069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 9.9719069698
MESH:D005355 Fibrosis Carbon Tetrachloride 23.1418705752
MESH:D005355 Fibrosis Cyclosporine 23.1412168785 12639820
MESH:D005355 Fibrosis Dietary Fats 23.1418296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 23.1420067830
MESH:D005355 Fibrosis Tretinoin 23.1417994277
MESH:D005756 Gastritis Acetaminophen 3.2216983495
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.2416452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.788708960
MESH:D005909 Glioblastoma Doxorubicin 14.6417150277
MESH:D005909 Glioblastoma Fenretinide 14.6416187019
MESH:D005909 Glioblastoma Okadaic Acid 14.6417312396
MESH:D005909 Glioblastoma Tretinoin 14.6417312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1410696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 6.8315692506
MESH:D006258 Head and Neck Neoplasms Tretinoin 6.8316096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.7116084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.7211294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 5.729664655 14991402
MESH:D006331 Heart Diseases Doxorubicin 3.1816495754 12587719 18006777 16879835 16244372 16144979 17875725 14766674 18674790 16707910 16244371 17888722 16330681
MESH:D006333 Heart Failure Doxorubicin 3.0717481944
MESH:D006394 Hemangiosarcoma Doxorubicin 3.5115692506
MESH:D006402 Hematologic Diseases Zidovudine 4.3012579204
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.9815720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9411000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.1819900420 19110552
MESH:D006509 Hepatitis B Lamivudine 4.7017703166
MESH:D019694 Hepatitis B, Chronic Lamivudine 4.7015631357 15274664 12044531 15309715 16476009
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.4715340226 16120746 12621046
MESH:D006558 Herpes Genitalis Estradiol 4.5815709030
MESH:D015658 HIV Infections Lamivudine 6.2511141242 20032539 9296927 17530837
MESH:D015658 HIV Infections Zidovudine 6.2511698656 11141242 11363243 20032539 17358032
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.2917440010
MESH:D006689 Hodgkin Disease Doxorubicin 6.2618501091 17606976 15147373
MESH:D006689 Hodgkin Disease sodium arsenite 6.2612676792
MESH:D019584 Hot Flashes Estradiol 3.3017088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.5916354765 15340226 18606429 8697196 16959395
MESH:D006930 Hyperalgesia Acetaminophen 6.4716870215
MESH:D006930 Hyperalgesia Tretinoin 6.4716870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.0916899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.2021332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.1416778211
MESH:D006949 Hyperlipidemias Dietary Fats 3.2121332399
MESH:D006973 Hypertension Cyclosporine 4.3310903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.3318670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.6615338365
MESH:D007248 Infertility, Male Atrazine 6.1012948887
MESH:D007248 Infertility, Male sodium arsenite 6.1015346721 12646999
MESH:D007249 Inflammation Dietary Fats 16.8020412841
MESH:D007249 Inflammation Diethylnitrosamine 16.8018785209
MESH:D007249 Inflammation Flavonoids 16.8017296493
MESH:D007249 Inflammation Mustard Gas 16.809357497 11428620 17524151 8975870 9260866 16001271 11402378 11428647 11428631
MESH:D007249 Inflammation Tamoxifen 16.8019457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 16.8012200463 12878042
MESH:D007333 Insulin Resistance Dietary Fats 6.3911836018 18457598
MESH:D007333 Insulin Resistance Estradiol 6.3916393666 16627594
MESH:D007410 Intestinal Diseases Tretinoin 3.3417994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.6216580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.6215992940 17551590
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.9915604871
MESH:D007674 Kidney Diseases Acetaminophen 16.2315629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 16.2318776723 10903974 8314463
MESH:D007674 Kidney Diseases Doxorubicin 16.2316775033 15699352 15369732
MESH:D007674 Kidney Diseases Estradiol 16.2315618244
MESH:D007674 Kidney Diseases sodium arsenite 16.2320008137
MESH:D007676 Kidney Failure, Chronic Doxorubicin 8.8116707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 8.8116518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 24.4516705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 24.4516705839
MESH:D007680 Kidney Neoplasms Cyclosporine 24.4512371664
MESH:D007680 Kidney Neoplasms Estradiol 24.4515610895
MESH:D007680 Kidney Neoplasms Tamoxifen 24.4518625569
MESH:D007680 Kidney Neoplasms Zidovudine 24.4512579204
MESH:D007938 Leukemia Tretinoin 2.5417143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.7016085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell marker/mechanism 16038780
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 4.0220370541
MESH:D007951 Leukemia, Myeloid Tretinoin 3.3019285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0016294345 17596541 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.8617301526 9834237 17294898 19029980 19642359 16140955 16788101 12679006 16823087 16331271 17649720 17368321 16935935 15748426 17339181 17506722 17361223 17217047 17107899 16766008 16891316 17712046 19075265 19225113 19035177
MESH:D007972 Leukoplakia, Oral Fenretinide 5.5916707609
MESH:D017880 Limb Deformities, Congenital Tretinoin 2.999224671
MESH:D008064 Lipidoses Tamoxifen 2.8417567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 9.5311408273 16221502 17334410 16943688 21278145 11903743 16239168 17174718 17157831
MESH:D008103 Liver Cirrhosis Dietary Fats 9.5318296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 9.5318665156 20032147 19638242 18522880 18407596
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 7.8518481824 17976157 15362042 14716496 17944888 17481882 17766677 17714472 16116963 18376398 11481614 17922224 12958196 18251166 17721639 12649538 17525996 12445418 15893842 15931870 15876570 18395914 12445421 16638106 15057751 16033810 17708605 16011737 17565644 16015684 12632512 18277467 12741479 12546737 16192424 15959796 16027843 18412020 18339082 18263696 15650968 18054572 15730626 18472094 15996030 16097048 18210741 17869086 12667390 16136751 15673190 17900296 14724832 15818738 18418968 12898905 16248980 18006644 18166357 14620537 18705752 18472332 15123356 15925388 10355542 15052691 18156304 14748882 18317297 17557913 17761835 17698563 18187930 12389079 17640975 12609069 12632514 18395095 18205269 12666154 18429990 17823541 12586293 14716833 18279442 14512876 17631135 15370692 15338365 18420326 20821823 17805973 13678700
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 7.8516439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 7.8514716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 7.8518564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 7.8512878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 7.8516248980 18397230
MESH:D008107 Liver Diseases Acetaminophen 5.6919014921 16611625 19784758 12969438 11587558 16610002 12587719 19460945
MESH:D008107 Liver Diseases Carbon Tetrachloride 5.6917285989 15720792 16964402 16246199 15830285
MESH:D008107 Liver Diseases Diethylnitrosamine 5.6917034775
MESH:D017093 Liver Failure Carbon Tetrachloride 3.7315123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.1316871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.1314706259 16899240
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 15.567678174
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 15.5619294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 15.5621047994 19690152 20118626 19638242 19256749 18754104 20583210 18644402 19833225 19073162 19255062 19426721 9163691 21278145 19254457 20137499 2862719 12112319 20492335 18977376 2422723 19499222 21167192 16942905 18978307 20452335 20434301 12771043 15885732 19294768 21071580 19427195 19996281 19812893 19551842 19090486 19642983 20501860 15175105 20101389 18648771 19850985 10737359 20405173
MESH:D008113 Liver Neoplasms sodium arsenite 15.5616712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 15.5616684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 15.5616984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 15.636135515 2876784 2876786
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 15.6315583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 15.6318775883 19004024 19539802 17942915 18253720 19519916 18093689 18282651 18164116 16842330 19126423 9362446 18079962 17854601 16267830 18308698 19009564 2563599 18544905 17174075 3124819 21159647
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 15.6317085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 15.6312151625
MESH:D008171 Lung Diseases Mustard Gas 10.6518161513 18702808
MESH:D008171 Lung Diseases Ozone 10.658266340 19066396
MESH:D008171 Lung Diseases sodium arsenite 10.6519095001
MESH:D055370 Lung Injury Ozone 3.4220417186
MESH:D008175 Lung Neoplasms Diethylnitrosamine 11.7920512841 21163286 6695378 20970405
MESH:D008175 Lung Neoplasms Doxorubicin 11.796189445 17418594
MESH:D008175 Lung Neoplasms Mustard Gas 11.793148597 8781369
MESH:D008175 Lung Neoplasms Ozone 11.798597069 7614698
MESH:D008175 Lung Neoplasms sodium arsenite 11.7915276417 17077188 17306315 16712894 19931552
MESH:D008175 Lung Neoplasms Tamoxifen 11.7918625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 11.7919555203 11884234
MESH:D008175 Lung Neoplasms Zidovudine 11.7918800350
MESH:D008223 Lymphoma Doxorubicin 3.1416098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.4317654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.1315621674
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.3219428831
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 11.9215458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 11.9216891317 11807958 11408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 11.9210697514
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 11.9214580682 19196723 11731420 16827153 19196722
MESH:D020149 Manganese Poisoning Estradiol 11.1419453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.1419453300
MESH:D008527 Medulloblastoma Tretinoin 2.6017453147
MESH:D008545 Melanoma Doxorubicin 8.7816827129
MESH:D008545 Melanoma Fenretinide 8.7816270382
MESH:D008545 Melanoma sodium arsenite 8.7819082730 16487513
MESH:D008545 Melanoma Tamoxifen 8.7812393984 19393235
MESH:D008545 Melanoma Tretinoin 8.7816752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.7415990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.1419513568
MESH:D008591 Meningomyelocele Tretinoin 3.9916940565
MESH:D008654 Mesothelioma Atrazine 5.921916698
MESH:D008654 Mesothelioma Doxorubicin 5.9217638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.3416801185
MESH:D008679 Metaplasia Ozone 4.6510496685
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 5.3917358032
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.1015792986
MESH:D009062 Mouth Neoplasms Fenretinide 3.9816274795
MESH:D052016 Mucositis Doxorubicin 4.3517415656
MESH:D009190 Myelodysplastic Syndromes Tretinoin 2.8217596541
MESH:D009203 Myocardial Infarction Doxorubicin 2.7619429709 15857846
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6712213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 2.9416810080
MESH:D009336 Necrosis 2,4-dinitrotoluene 8.8718551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 8.877678174 18551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.409029167 3581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 8.4018259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 8.4019393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3619410462
MESH:D009369 Neoplasms Fenretinide 7.0715958647 17353921
MESH:D009369 Neoplasms sodium arsenite 7.0711559025
MESH:D009369 Neoplasms Tretinoin 7.0716946489 16594593
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.2420056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.5519189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.2917289903
MESH:D009401 Nephrosis Doxorubicin 4.3416636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.9917954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.0619348381 18481113
MESH:D009404 Nephrotic Syndrome Doxorubicin 8.0615640375 16889571
MESH:D009421 Nervous System Malformations Estradiol 13.9011399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 13.9014600291
MESH:D009421 Nervous System Malformations Tretinoin 13.909125849
MESH:D009436 Neural Tube Defects sodium arsenite 6.3312854658
MESH:D009436 Neural Tube Defects Tretinoin 6.339142499
MESH:D009447 Neuroblastoma Doxorubicin 3.0215555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 6.9918514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 6.9920387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6620387270
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 5.2316303764
MESH:D009503 Neutropenia Mustard Gas 3.5716761898 7688884
MESH:D009765 Obesity Dietary Fats 2.1711836018 21332399 16723640 20518802 20132043 19632207 18674790 18457598 17217161
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 7.6116049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 7.6116049721
MESH:D012516 Osteosarcoma Doxorubicin 3.7615930896
MESH:D010051 Ovarian Neoplasms therapeutic 16936753
MESH:D010051 Ovarian Neoplasms CD 437 13.3117474084
MESH:D010051 Ovarian Neoplasms Estradiol 13.3119401270
MESH:D010051 Ovarian Neoplasms Fenretinide 13.3116133793
MESH:D010051 Ovarian Neoplasms sodium arsenite 13.3117306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 13.3116936753
MESH:D010146 Pain Acetaminophen 5.4116870215
MESH:D010146 Pain Tretinoin 5.4116870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 7.6916540662
MESH:D010190 Pancreatic Neoplasms Fenretinide 7.6915580305
MESH:D010190 Pancreatic Neoplasms Tretinoin 7.6915976015
MESH:D010212 Papilloma Hydrogen Peroxide 3.6612065085
MESH:D010300 Parkinson Disease Atrazine 3.1017218051
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8012520081
MESH:D010538 Peritonitis Ozone 3.7016369182
MESH:D010787 Photosensitivity Disorders 4-hydroxy-2-nonenal 5.0511550810
MESH:D003557 Phyllodes Tumor Doxorubicin 4.7017983394
MESH:D010997 Pleural Neoplasms Doxorubicin 4.7017638057
MESH:D011014 Pneumonia Ozone 3.9518007984 18929643 18381685
MESH:D011041 Poisoning Mustard Gas 3.4015727166
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1418163543
MESH:D011230 Precancerous Conditions Cyclosporine 7.7112371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 7.712563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.7511118676 11896295 11399792 11222880
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.3415572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.4920887781
MESH:D011471 Prostatic Neoplasms Calcitriol 1.8716289102 12479363 18247401 16644109 15754350
MESH:D011471 Prostatic Neoplasms Doxorubicin 1.8715749863 15897917 16888761 18437689 16729912 16868541
MESH:D011471 Prostatic Neoplasms Estradiol 1.8716740699
MESH:D011471 Prostatic Neoplasms Fenretinide 1.8717024972
MESH:D011471 Prostatic Neoplasms sodium arsenite 1.8716039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.8715067354
MESH:D011507 Proteinuria Tretinoin 3.2016636307
MESH:D011537 Pruritus Mustard Gas 3.6518058305
MESH:D011565 Psoriasis Cyclosporine 2.0616882103
MESH:D011625 Pterygium Tretinoin 4.3516723453
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.7517620002 17894541 17720292 10334151 17266442
MESH:D051437 Renal Insufficiency Doxorubicin 3.7917922066
MESH:D012135 Respiratory Sounds Atrazine 4.0911874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4218990726
MESH:D012162 Retinal Degeneration Fenretinide 4.0716303925
MESH:D012206 Rhabdomyolysis Lamivudine 5.099296927
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.6916283617 16116481
MESH:D012509 Sarcoma Doxorubicin 3.6117203757 16767912 15625365 15675481 17710206 18313854
MESH:D012512 Sarcoma, Ewing's Doxorubicin 3.8216326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.3517846226
MESH:D012640 Seizures 2,4-dinitrotoluene 4.8618551238
MESH:D012640 Seizures 2,6-dinitrotoluene 4.8618551238
MESH:D012871 Skin Diseases Mustard Gas 2.5915451306 12880345 16961503
MESH:D012878 Skin Neoplasms Doxorubicin 28.1615692506
MESH:D012878 Skin Neoplasms Fenretinide 28.1616467112
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 28.1612065085
MESH:D012878 Skin Neoplasms Okadaic Acid 28.1612628509
MESH:D012878 Skin Neoplasms sodium arsenite 28.1619524636 18572023
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 28.168532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 28.1616192470
MESH:D012878 Skin Neoplasms Tretinoin 28.1616467112
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.1315625365 17203757 16767912
MESH:D013088 Spermatocele Tamoxifen 3.8416709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.6019457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.4512854658
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.1718456281
MESH:D013274 Stomach Neoplasms Tretinoin 3.1717261132
MESH:D013274 Stomach Neoplasms Zidovudine 3.1717696246
MESH:D024801 Tauopathies Camptothecin 5.1816930453
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4512697716
MESH:D013964 Thyroid Neoplasms Butyrates 14.4017967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 14.407505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 14.4016010429 17909728
MESH:D013964 Thyroid Neoplasms Tretinoin 14.4017045167 16026305
MESH:D013978 Tibial Fractures Estradiol 4.2319048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.4016051514
MESH:D014376 Tuberculosis Tretinoin 2.9516040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 21.2216049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 21.2216049721
MESH:D001749 Urinary Bladder Neoplasms CD 437 21.2216720286
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 21.2217653716
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 21.2216720286
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 21.2211723127 16452187 16712894 17306315
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 21.2217572228 16712894 8653321
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 10.5110091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 10.5110091137
MESH:D014581 Urticaria Acetaminophen 2.5710982225
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 13.7316154183
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 13.7311813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 13.7316129372
MESH:D014604 Uveal Neoplasms Tretinoin 4.1616752155
MESH:D014605 Uveitis Cyclosporine 3.531336536
MESH:D014625 Vaginal Neoplasms Zidovudine 4.3312579204
MESH:D014652 Vascular Diseases sodium arsenite 3.9817056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1412125929
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.7916364871 17334414 17678736 17638931
MESH:D014820 Vitiligo Tretinoin 3.6416761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8015886252
MESH:D015430 Weight Gain Dietary Fats 3.3716723640
MESH:D009396 Wilms Tumor Tretinoin 3.5916287080
MESH:D014985 Xerophthalmia Cyclosporine 3.9917120751
Pathway ID Pathway Name
KEGG:04110 Cell cycle
KEGG:04350 TGF-beta signaling pathway
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018