AutismKB 2.0

Annotation Detail for RBM3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RBM3 ( IS1-RNPL,RNPL )
Gene Full Name: RNA binding motif (RNP1, RRM) protein 3
Band: Xp11.23
Quick LinksEntrez ID:5935; OMIM: 300027; Uniprot ID:RBM3_HUMAN; ENSEMBL ID: ENSG00000102317; HGNC ID: 9900
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1944Breast cancer
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C049325 1,2-dithiol-3-thione 1,2-dithiol-3-thione results in increased expression of RBM3 mRNAincreases expression 15302862
C010914 2,4-diaminotoluene 2,4-diaminotoluene results in increased expression of RBM3 mRNAincreases expression 20713471
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of RBM3 mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of RBM3 mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of RBM3 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RBM3 mRNAaffects expression 16483693
D002258 Carbonyl Cyanide m-Chlorophenyl Hydrazone Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of RBM3 mRNAdecreases expression 15075239
C019304 ciprofibrate ciprofibrate results in increased expression of RBM3 mRNAincreases expression 12771043
D002995 Clofibric Acid Clofibric Acid affects the expression of RBM3 mRNAaffects expression 17602206
C030123 coumarin coumarin results in increased expression of RBM3 mRNAincreases expression 18480146
D016572 Cyclosporine Cyclosporine results in increased expression of RBM3 mRNAincreases expression 20106945
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of RBM3 mRNAincreases expression 12771043
D004317 Doxorubicin Doxorubicin results in increased expression of RBM3 mRNAincreases expression 17888722
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of RBM3 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of RBM3 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RBM3 mRNAaffects cotreatment|increases expression 17942748
D015655 1-Methyl-4-phenylpyridinium 1-Methyl-4-phenylpyridinium results in decreased expression of RBM3 mRNAdecreases expression 14649730
D019810 Sodium Azide Sodium Azide results in decreased expression of RBM3 mRNAdecreases expression 15075239
D010126 Ozone Ozone results in increased expression of RBM3 mRNAincreases expression 12763052
C006253 pirinixic acid pirinixic acid results in increased expression of RBM3 mRNAincreases expression 18445702
D011794 Quercetin Quercetin results in decreased expression of RBM3 mRNAdecreases expression 15309432
C009250 sevoflurane sevoflurane affects the expression of RBM3 mRNAaffects expression 15967596
D013629 Tamoxifen Tamoxifen affects the expression of RBM3 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RBM3 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of RBM3 mRNAincreases expression 17942748
C423915 TO-901317 TO-901317 results in increased expression of RBM3 mRNAincreases expression 15302862
D014303 Trinitrotoluene Trinitrotoluene affects the expression of RBM3 mRNAaffects expression 21346803
D014501 Uranium Uranium results in increased expression of RBM3 mRNAincreases expression 15672453
C005460 uranyl acetate uranyl acetate results in increased expression of RBM3 mRNAincreases expression 15672453
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.3414745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.8715322242 11752688 14514962
MESH:D000014 Abnormalities, Drug-Induced Trinitrotoluene 7.877525203
MESH:D000138 Acidosis Ammonium Chloride 3.3518287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7317505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.9218653653
MESH:D000230 Adenocarcinoma Doxorubicin 4.2117418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.2114692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 6.273712494
MESH:D000236 Adenoma Diethylnitrosamine 6.2710737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 16.0516434500 19052882 17620307 19061943 17162532 18056438
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.0516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.0516835633
MESH:D000419 Albuminuria Doxorubicin 4.3421441931
MESH:D000544 Alzheimer Disease Ozone 2.3915513908
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7611748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.0517084956
MESH:D000799 Angioedema Acetaminophen 3.6310982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2611256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5415885639
MESH:D001172 Arthritis, Rheumatoid Ozone 2.5115570426
MESH:D001249 Asthma Ozone 2.5817854713 16373670
MESH:D001260 Ataxia Telangiectasia Quercetin 4.7715336622
MESH:D001321 Autistic Disorder Acetaminophen 1.4418445737
MESH:D001327 Autoimmune Diseases Quercetin 4.2019761891
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.811440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.1419483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.1412125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5815340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6315746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.4914601052
MESH:D001932 Brain Neoplasms Doxorubicin 3.6317150277
MESH:D001943 Breast Neoplasms marker/mechanism 19734850
MESH:D001943 Breast Neoplasms 2,4-diaminotoluene 2.8611921183
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.8617474063
MESH:D001943 Breast Neoplasms Doxorubicin 2.8619526202 18234424 16115903 15993339 15136595 15567936 16096432 15692762 11325840 16935488 17983394 16826403 18628466 15634643 17369602 16322301 16264153 15994142 18382427 17426702 15668708 15939500 18695136 16595493
MESH:D001943 Breast Neoplasms Quercetin 2.8618628248
MESH:D001943 Breast Neoplasms Tamoxifen 2.8611161223 18997820 20544844 21152245 19244106 20065188 20005174 17242785 18855134 16873071 19289846 20390343 19189210 21138602 19142967 17261762 19103187 18821012 15565566 19200415 18351453 19487384 19115204 19084267 18815881 19059307 17893378 17440819 18984771 20859285 16818667 16273361 19155303 19288272 19189212 19011961 15668708 19410462 16202921 17049068 20135344 19066611 19221464 18425577 18629630
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.8620435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.5115516495 16777450 18417511 14754758 18315731 17626835 19059883
MESH:D002100 Cachexia Ozone 4.5316183385
MESH:D002105 Cadmium Poisoning Quercetin 5.3316962696
MESH:D002276 Carcinoid Tumor Doxorubicin 4.6016051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6316835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.3019066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 13.5516705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 13.557296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 13.553084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 13.5520084675 19171122 11831363 20514400 16779866 17978847 16807293 18788625 19335982 19208518 21159647 16878318 18393292 16681979 20935162 10672840 18665156 16935385 17162532 19919837 10737359 17055752 19822196 18691550 16830150 18056438 18785209 20432363 20101231 17138121 19394651 19539802 19418558 16502159 20524982 19701751 19519916 16328049 16540662 20214788 19383236 16288022 20512989 16569478 3581430 17173139 3084413 18506893 19107877 20727157 20007298 17761372 18494052 18978308 17428255 18971187 18210153 19052882 16698587
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 13.5518059187 16234567 17876044 16023760
MESH:D006528 Carcinoma, Hepatocellular Quercetin 13.5519519916 12508355
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 13.5516924424
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.7517234771
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 6.227296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 6.2216201981 1485588
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 2.586189445
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.4317572228
MESH:D006332 Cardiomegaly Quercetin 6.4219794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.4218850075 16120746 18670907
MESH:D009202 Cardiomyopathies Doxorubicin 3.3917974986 16364871 15811867 16455267 16731534 17329180 17924179 16242529 15792986 17131338 16278810 17308081 17928571 15505089 17382496 17007740 16612575 15476868 16269455 17351982 16952015 16651473 16109756 18627295 17519947
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.8717334414 16243910
MESH:D002386 Cataract Acetaminophen 7.1110977129
MESH:D002386 Cataract Trinitrotoluene 7.1115817613 14694615
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 10.327505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.3212371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 10.3217174075 7505956 2727394 21159647
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.7419052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.7416835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 17.9519486331 9022650
MESH:D002779 Cholestasis Cyclosporine 17.9519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 17.9517333356 11677210 17681005 15861022 16919318 16105132 17110522
MESH:D002779 Cholestasis pirinixic acid 17.9519176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0215668235 12621046 8697196 15340226 16354765
MESH:D003110 Colonic Neoplasms Quercetin 2.3911134977 15741050 19056647 17191121 17148506 16640504 19440933
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.6718259882 18802399
MESH:D015179 Colorectal Neoplasms Quercetin 2.6718852136 18095365
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.6917141729 14669216
MESH:D000013 Congenital Abnormalities Trinitrotoluene 8.6915095906
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2510048152 20055451 15322242
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.5418551238
MESH:D003490 Cyanosis Trinitrotoluene 10.5418551238
MESH:D003711 Demyelinating Diseases Tamoxifen 4.1519031437
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.6111906362 14531868 18759878 2524372 8156756 11298694 12868966 8970840
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3318249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.303621924 2952479
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.5619496084
MESH:D003924 Diabetes Mellitus, Type 2 coumarin 6.8919647726
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.8920387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.8917107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.3019279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 17.7021346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 17.706679447 9653073 16192314 8291058 18692083 9022650 11289319 7440962 6482804 9328219 18648102 1440618 18289764
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 17.7011743745 10915739 19164858 16393943 14550746 14986274 12594235 15968718 19739265 11287661 19923254 11834606 2444490 19416960 19420014 16227642 14725611 10774834 11739529 19370779 10663392 16109766 18713872 16177239 12540782 12392966 15619225 17906064 11529661 17522070 16781746 11421492 12153990 12705907 17562736 18071297 19085960 11461765 16485898 16081117 12958197
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 17.7019107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 17.7017416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 17.7020420201
MESH:D056486 Drug-Induced Liver Injury Trinitrotoluene 17.7021346803 18551238
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.8919426721
MESH:D004362 Drug Toxicity Doxorubicin 7.6018602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.6011462148
MESH:D004487 Edema pirinixic acid 5.9212083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.9212711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.6915322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.2812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.2819031437
MESH:D016889 Endometrial Neoplasms Doxorubicin 7.1117359293
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.1116202921 17893378 20544844 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.849294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.9418037988
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9016302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.063581430
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8611564622
MESH:D005234 Fatty Liver Cyclosporine 22.6219224547
MESH:D005234 Fatty Liver Diethylnitrosamine 22.6220387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 22.6215345470
MESH:D005234 Fatty Liver pirinixic acid 22.6219236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 22.6219224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1116709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2511858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.816705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.3214745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 10.7419069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 10.7419069698
MESH:D005355 Fibrosis Cyclosporine 13.5712639820 12168785
MESH:D005355 Fibrosis Quercetin 13.5719474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 13.5720067830
MESH:D005756 Gastritis Acetaminophen 3.4616983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.018708960
MESH:D005909 Glioblastoma Doxorubicin 6.9417150277
MESH:D005909 Glioblastoma Quercetin 6.9419804834
MESH:D005910 Glioma Quercetin 2.9717643826
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.847505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3810696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 3.3915692506
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2210048152 11294989
MESH:D006331 Heart Diseases Doxorubicin 3.3417875725 17888722 16707910 16144979 18674790 16879835 18006777 14766674 16330681 16244371 16495754 12587719 16244372
MESH:D006333 Heart Failure Doxorubicin 6.6217481944
MESH:D006333 Heart Failure pirinixic acid 6.6220558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.7115692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2115720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1511000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.316705139
MESH:D006529 Hepatomegaly pirinixic acid 13.2819176532 16221962 18467677 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 13.2816120746 15340226 12621046
MESH:D006529 Hepatomegaly Trinitrotoluene 13.2815817613
MESH:D006689 Hodgkin Disease Doxorubicin 3.2415147373 18501091 17606976
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8316354765 8697196 18606429 16959395 15340226
MESH:D006930 Hyperalgesia Acetaminophen 2.5416870215
MESH:D006943 Hyperglycemia pirinixic acid 8.6320558911
MESH:D006943 Hyperglycemia Quercetin 8.6311834736 18262572
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.7315034207
MESH:D006973 Hypertension Cyclosporine 8.1110903974
MESH:D006973 Hypertension Quercetin 8.1118356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.1118670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6016569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.4317937319
MESH:D007248 Infertility, Male Trinitrotoluene 6.4312150543
MESH:D007249 Inflammation Diethylnitrosamine 7.6418785209
MESH:D007249 Inflammation Tamoxifen 7.6419457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.6412200463 12878042
MESH:D007251 Influenza, Human Quercetin 4.3016624496
MESH:D007333 Insulin Resistance pirinixic acid 2.5016306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.818074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1516580747
MESH:D007627 Keloid Quercetin 4.7517086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2315604871
MESH:D007674 Kidney Diseases Acetaminophen 13.4612587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 13.468314463 10903974 18776723
MESH:D007674 Kidney Diseases Doxorubicin 13.4615699352 16775033 15369732
MESH:D007674 Kidney Diseases Quercetin 13.4616962696
MESH:D007676 Kidney Failure, Chronic Doxorubicin 3.9616707910
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 16.3416705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 16.346582329
MESH:D007680 Kidney Neoplasms Cyclosporine 16.3412371664
MESH:D007680 Kidney Neoplasms Tamoxifen 16.3418625569
MESH:D007859 Learning Disorders sevoflurane 4.5719212262
MESH:D007938 Leukemia Quercetin 3.0517468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.9416085563
MESH:D008064 Lipidoses Tamoxifen 3.0117567588 15342952
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.7118407596 20032147 18522880 19638242 18665156
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.079327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 6.4516595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.4515474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 6.4512741479
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 6.4518564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.4512878042
MESH:D008107 Liver Diseases Acetaminophen 3.7212969438 19460945 19784758 11587558 19014921 16611625 12587719 16610002
MESH:D008107 Liver Diseases Diethylnitrosamine 3.7217034775
MESH:D017114 Liver Failure, Acute Acetaminophen 3.0516871587 17185352
MESH:D008113 Liver Neoplasms ciprofibrate 20.6812771043
MESH:D008113 Liver Neoplasms Clofibric Acid 20.6817602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 20.6819499222 19427195 18977376 10737359 19642983 21167192 15175105 19073162 20137499 2422723 20501860 9163691 18978307 20583210 19426721 20492335 19690152 18754104 19254457 20434301 19294768 19850985 2862719 19256749 12771043 21047994 19638242 15885732 20101389 19996281 12112319 20452335 21071580 19255062 18648771 20405173 20118626 18644402 21278145 16942905 19812893 19833225 19090486 19551842
MESH:D008113 Liver Neoplasms pirinixic acid 20.6816377806 20007298 15890375
MESH:D008113 Liver Neoplasms Quercetin 20.6818980244
MESH:D008113 Liver Neoplasms Tamoxifen 20.6816684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 20.6816984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 17.276587162 3712494 1399818 598648
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 17.2718164116 9362446 18253720 17174075 16842330 19539802 18282651 19009564 2563599 16267830 18308698 19004024 18544905 19519916 18079962 21159647 17854601 18775883 19126423 18093689 17942915 3124819
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 17.2716842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Quercetin 17.2719519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 17.2712151625
MESH:D008171 Lung Diseases Ozone 3.248266340 19066396
MESH:D055370 Lung Injury Ozone 3.6420417186
MESH:D008175 Lung Neoplasms Diethylnitrosamine 8.2120970405 21163286 6695378 20512841
MESH:D008175 Lung Neoplasms Doxorubicin 8.216189445 17418594
MESH:D008175 Lung Neoplasms Ozone 8.217614698 8597069
MESH:D008175 Lung Neoplasms Quercetin 8.2116280456
MESH:D008175 Lung Neoplasms Tamoxifen 8.2118625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.2111884234 19555203
MESH:D008223 Lymphoma Doxorubicin 3.3116098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.6217654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.3615621674
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.5519428831
MESH:D008325 Mammary Neoplasms, Experimental 2,4-diaminotoluene 9.3611921183
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 9.3615458769
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 9.3619196722 16827153 11731420 14580682 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 4.3419453300
MESH:D008545 Melanoma Doxorubicin 3.2916827129
MESH:D008545 Melanoma Tamoxifen 3.2912393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.9715990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.3619513568
MESH:D008569 Memory Disorders sevoflurane 4.5519212262
MESH:D008654 Mesothelioma Doxorubicin 2.9817638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5816801185
MESH:D008679 Metaplasia Ozone 4.8910496685
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.3115792986
MESH:D052016 Mucositis Doxorubicin 4.5817415656
MESH:D009135 Muscular Diseases pirinixic acid 3.3016239165
MESH:D009203 Myocardial Infarction Doxorubicin 9.0015857846 19429709
MESH:D009203 Myocardial Infarction pirinixic acid 9.0019151258
MESH:D009203 Myocardial Infarction Quercetin 9.0019595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8512213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.9116411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 7.9119207477
MESH:D009336 Necrosis 2,4-dinitrotoluene 9.9818551238
MESH:D009336 Necrosis Trinitrotoluene 9.9818551238
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 12.893581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 12.893581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 12.8918259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 12.8919393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4519410462
MESH:D009369 Neoplasms pirinixic acid 4.7117405874
MESH:D009369 Neoplasms Quercetin 4.7115185748
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.7919200415 19196722 19189210
MESH:D009401 Nephrosis Doxorubicin 4.5616636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2317954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.7119348381 18481113
MESH:D009404 Nephrotic Syndrome Doxorubicin 8.7115640375 16889571
MESH:D009410 Nerve Degeneration 1-Methyl-4-phenylpyridinium 4.8817433543
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.0114600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 2.786679447
MESH:D009447 Neuroblastoma Doxorubicin 3.1615555623
MESH:D019636 Neurodegenerative Diseases 1-Methyl-4-phenylpyridinium 13.2416353238
MESH:D019636 Neurodegenerative Diseases Acetaminophen 13.2418514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 13.2420387270
MESH:D020078 Neurogenic Inflammation Quercetin 4.1717929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9020387270
MESH:D009765 Obesity pirinixic acid 1.7620558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 14.1312819281 16049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 14.136482804 4026338
MESH:D009784 Occupational Diseases Trinitrotoluene 14.1314694615 17852074 12819281
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.813988306
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.0219495926
MESH:D012516 Osteosarcoma Doxorubicin 3.9515930896
MESH:D010051 Ovarian Neoplasms Quercetin 2.6719005980
MESH:D010146 Pain Acetaminophen 2.2316870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.1416540662
MESH:D010190 Pancreatic Neoplasms Quercetin 5.1416965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4911578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.287296757
MESH:D010300 Parkinson Disease 1-Methyl-4-phenylpyridinium 4.0617433543
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0412520081
MESH:D010538 Peritonitis Ozone 3.9216369182
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.266228378
MESH:D003557 Phyllodes Tumor Doxorubicin 4.9417983394
MESH:D010997 Pleural Neoplasms Doxorubicin 4.9417638057
MESH:D011014 Pneumonia Ozone 4.1818007984 18381685 18929643
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3618163543
MESH:D011230 Precancerous Conditions Cyclosporine 14.3012371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 14.302563599
MESH:D011230 Precancerous Conditions Quercetin 14.3019056647
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.9811896295 11399792 11222880 11118676
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.7116729912 18437689 15749863 15897917 16868541 16888761
MESH:D011471 Prostatic Neoplasms Quercetin 2.7117292933 14715546
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.7115067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.1015861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.1616882103
MESH:D051437 Renal Insufficiency Doxorubicin 4.0117922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.2919058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6418990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.223692021
MESH:D012509 Sarcoma Doxorubicin 3.8115625365 17203757 17710206 15675481 16767912 18313854
MESH:D012512 Sarcoma, Ewing's Doxorubicin 4.0414601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.5817846226
MESH:D012554 Schistosomiasis japonica Quercetin 5.3316862918
MESH:D012640 Seizures 2,4-dinitrotoluene 5.7318551238
MESH:D012640 Seizures Trinitrotoluene 5.7318551238
MESH:D012878 Skin Neoplasms Doxorubicin 5.3615692506
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.3616192470
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.3617203757 16767912 15625365
MESH:D013088 Spermatocele Ethinyl Estradiol 10.8516709447
MESH:D013088 Spermatocele Tamoxifen 10.8516709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.8319457130
MESH:D013163 Splenomegaly Trinitrotoluene 4.9915817613
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7518456281
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6912697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 11.086582329 3712494 1399818 7505956 6587162
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 11.087505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 11.0816010429 17909728
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 14.9316049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 14.938074119
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 14.9317653716
MESH:D001749 Urinary Bladder Neoplasms Quercetin 14.9316720314
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 14.938653321 17572228 16712894
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.1010091137
MESH:D014581 Urticaria Acetaminophen 2.7810982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1014692618
MESH:D014605 Uveitis Cyclosporine 3.771336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3812125929
MESH:D014689 Venous Insufficiency coumarin 5.5612708602
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3515869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.0116364871 17678736 17638931 17334414
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0415886252
MESH:D014985 Xerophthalmia Cyclosporine 4.2317120751
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved