AutismKB 2.0

Annotation Detail for RGS1


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Basic Information Top
Gene Symbol:RGS1 ( 1R20,BL34,IER1,IR20 )
Gene Full Name: regulator of G-protein signaling 1
Band: 1q31.2
Quick LinksEntrez ID:5996; OMIM: 600323; Uniprot ID:RGS1_HUMAN; ENSEMBL ID: ENSG00000090104; HGNC ID: 9991
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
No data
Pathway IDPathway Name
200083CXCR4-mediated signaling events
Pathway IDPathway Name
P00026Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
P00027Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1770Melanoma
1934Cancer
Desease Name
Celiac Disease
IMMUNE
Desease Name
Celiac disease
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of RGS1 mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of RGS1 mRNAaffects expression 17562736
D015081 2-Naphthylamine 2-Naphthylamine results in increased expression of RGS1 mRNAincreases expression 18247414
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RGS1 mRNAaffects expression 16483693
D001151 Arsenic Arsenic affects the expression of RGS1 mRNAaffects expression 18414638
D001151 Arsenic Arsenic results in decreased expression of RGS1 mRNAdecreases expression 16835338
D001151 Arsenic RGS1 mRNA results in decreased susceptibility to Arsenicdecreases response to substance 17976673
C015001 arsenite arsenite results in decreased expression of RGS1 mRNAdecreases expression 18191166
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of RGS1 mRNAincreases expression 18247414
D004317 Doxorubicin Doxorubicin affects the expression of RGS1 mRNAaffects expression 15205334
D004391 Dust Dust results in increased expression of RGS1 mRNAincreases expression 17805423
D005472 Fluorouracil Fluorouracil affects the expression of RGS1 mRNAaffects expression 15205334
C051890 irinotecan irinotecan metabolite results in increased expression of RGS1 mRNAincreases expression 15956246
C051890 irinotecan irinotecan results in increased expression of RGS1 mRNAincreases expression 15956246
D007501 Iron Iron deficiency results in increased expression of RGS1 mRNAincreases expression 20368581
C029938 nickel sulfate nickel sulfate results in increased expression of RGS1 mRNAincreases expression 16780908
D009538 Nicotine Nicotine results in increased expression of RGS1 mRNAincreases expression 18247414
D011794 Quercetin Quercetin results in increased expression of RGS1 mRNAincreases expression 15309432
D014807 Vitamin D Vitamin D affects the expression of RGS1 mRNAaffects expression 20368581
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.5818287403
MESH:D055371 Acute Lung Injury nickel sulfate 4.3112718980 19131640 16100012 11954676
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 7.1520127859 20464547
MESH:D000230 Adenocarcinoma Doxorubicin 7.1517418594
MESH:D000230 Adenocarcinoma Fluorouracil 7.1517638652
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 6.603712494
MESH:D000236 Adenoma Benzo(a)pyrene 6.606695378
MESH:D018246 Adrenocortical Adenoma Arsenic 5.2417306315
MESH:D000419 Albuminuria Doxorubicin 4.5521441931
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 5.6716640825
MESH:D000544 Alzheimer Disease Iron 4.8616563566 16640825
MESH:D000544 Alzheimer Disease Nicotine 4.8616627626
MESH:D000740 Anemia Fluorouracil 9.2215504547 17963324 16511603
MESH:D000740 Anemia Iron 9.2216434484 16566752
MESH:D000743 Anemia, Hemolytic Quercetin 4.2417084956
MESH:D018798 Anemia, Iron-Deficiency Iron 4.6516569441 17162259 17147795 17163184 17375513
MESH:D000756 Anemia, Sideroblastic Iron 4.8216910769
MESH:D000799 Angioedema Acetaminophen 3.8710982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.0919183758
MESH:D001145 Arrhythmias, Cardiac Iron 4.3716604332
MESH:D020261 Arsenic Poisoning marker/mechanism 16835338
MESH:D020261 Arsenic Poisoning Arsenic 2.8716835338 12569548 18414634 16251483
MESH:D001260 Ataxia Telangiectasia Iron 13.1815336622
MESH:D001260 Ataxia Telangiectasia Quercetin 13.1815336622
MESH:D050197 Atherosclerosis Arsenic 7.0619371607 12928151
MESH:D050197 Atherosclerosis Iron 7.0616640825 16632123
MESH:D001321 Autistic Disorder Acetaminophen 2.1418445737
MESH:D001321 Autistic Disorder Iron 2.1417352947
MESH:D001327 Autoimmune Diseases Quercetin 4.4219761891
MESH:D001424 Bacterial Infections Iron 5.2116640825
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.0511289319 1440618
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.7314601052
MESH:D001932 Brain Neoplasms Doxorubicin 3.8117150277
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0017474063 20146248
MESH:D001943 Breast Neoplasms Doxorubicin 2.0016096432 15939500 11325840 19526202 18628466 16826403 15994142 16264153 16115903 16595493 17983394 16322301 15567936 15993339 18382427 15136595 16935488 18695136 17369602 15634643 17426702 15692762 18234424 15668708
MESH:D001943 Breast Neoplasms Fluorouracil 2.0019217205 16110121 16595493 16557594 18608205 18357371 15136595
MESH:D001943 Breast Neoplasms Quercetin 2.0018628248
MESH:D002105 Cadmium Poisoning Quercetin 5.5816962696
MESH:D002276 Carcinoid Tumor Doxorubicin 12.4616051944
MESH:D002276 Carcinoid Tumor Fluorouracil 12.4616051944
MESH:D002277 Carcinoma Fluorouracil 3.5717121937
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.5915504454 17687452
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 11.413581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.413084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 11.4116507464 17306315
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 11.4116023760 17876044 16234567 18059187
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 11.4116799960 17045692 17088986 18930000 17971768 16332177
MESH:D006528 Carcinoma, Hepatocellular Quercetin 11.4119519916 12508355
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.9717234771
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 10.797296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 10.7916201981 1485588
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 10.7918695887
MESH:D002294 Carcinoma, Squamous Cell Arsenic 10.8417687452 15504454 18922899
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 10.8420419170
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 10.846189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 10.8416757204 16280240 18986760 17066447
MESH:D002295 Carcinoma, Transitional Cell Arsenic 4.0818640142
MESH:D006332 Cardiomegaly Quercetin 3.3219794523
MESH:D009202 Cardiomyopathies Doxorubicin 8.1717329180 16278810 17007740 16731534 16455267 17519947 17924179 17382496 17308081 17351982 15476868 16952015 16612575 18627295 16242529 16651473 17974986 16269455 16364871 17928571 16109756 15505089 15792986 17131338 15811867
MESH:D009202 Cardiomyopathies Iron 8.1716640825
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 6.1917334414 16243910
MESH:D002311 Cardiomyopathy, Dilated Iron 6.1916604332
MESH:D002318 Cardiovascular Diseases Arsenic 3.4517938729 19152805 15738583
MESH:D002340 Carotid Artery Diseases Arsenic 4.3118022660 16973168
MESH:D002386 Cataract Acetaminophen 2.5810977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 2.767505956
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 3.159022650 19486331
MESH:D003110 Colonic Neoplasms arsenite 11.1615037631
MESH:D003110 Colonic Neoplasms Fluorouracil 11.1617172411 18772588 17169374 16340194 17725105 15001691 17016597 16510598 17287894 17018589
MESH:D003110 Colonic Neoplasms irinotecan 11.1617725105 17287894
MESH:D003110 Colonic Neoplasms Iron 11.1616640825
MESH:D003110 Colonic Neoplasms Quercetin 11.1619056647 11134977 17191121 19440933 15741050 17148506 16640504
MESH:D015179 Colorectal Neoplasms Doxorubicin 4.8418802399 18259882
MESH:D015179 Colorectal Neoplasms Fluorouracil 4.8417401013 18802399 17255274 20501625 16282729 15289873 18509181 14970324 17594712 16524972 15148649 17695437 17016601 17094418 17454858 18448328 16331619 16391804 18383874 18949393 16303861 18288408
MESH:D015179 Colorectal Neoplasms irinotecan 4.8416303861 17159606 16391804 18259882 18509181 15273666 17454858
MESH:D015179 Colorectal Neoplasms Quercetin 4.8418852136 18095365
MESH:D007644 Darier Disease Fluorouracil 4.8116733453
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 7.1918759878 2524372 12868966 11298694 8970840 8156756 14531868 11906362
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 7.1916780908 16823706 11298694
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.503621924 2952479
MESH:D003920 Diabetes Mellitus Iron 4.4516640825 16604332
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.7319496084
MESH:D003922 Diabetes Mellitus, Type 1 Iron 3.3616506275
MESH:D003924 Diabetes Mellitus, Type 2 Iron 3.0916506275
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 6.2418648102 1440618 9653073 6679447 18289764 9328219 18692083 16192314 8291058 7440962 6482804 11289319 9022650
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.2419420014 12153990 10774834 10663392 17562736 11529661 12392966 10915739 16393943 14725611 19923254 14550746 15619225 16081117 11743745 12705907 12594235 11421492 15968718 16177239 18713872 17522070 19164858 19085960 11739529 19739265 16485898 16227642 2444490 12540782 19370779 11461765 18071297 14986274 19416960 16109766 11834606 16781746 12958197 11287661 17906064
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 6.2417416283
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1319426721
MESH:D004362 Drug Toxicity Doxorubicin 3.6718602426
MESH:D020821 Dystonic Disorders Nicotine 5.9517881519
MESH:D016889 Endometrial Neoplasms Doxorubicin 3.4517359293
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.1918037988
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 7.243581430
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 7.2416530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 7.2415173087 17638652 16337965 16481741 16785472
MESH:D005234 Fatty Liver arsenite 8.4018296743
MESH:D005234 Fatty Liver Iron 8.4016640825
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.056705139
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.6119069698
MESH:D005355 Fibrosis arsenite 9.2218296743
MESH:D005355 Fibrosis Quercetin 9.2219474275
MESH:D005534 Foot Diseases Arsenic 5.596392382
MESH:D005621 Friedreich Ataxia Iron 5.4416640825 16604332
MESH:D005756 Gastritis Acetaminophen 3.7116983495
MESH:D005909 Glioblastoma Doxorubicin 7.3917150277
MESH:D005909 Glioblastoma Quercetin 7.3919804834
MESH:D005910 Glioma Fluorouracil 6.1916145905
MESH:D005910 Glioma Quercetin 6.1917643826
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.047505956
MESH:D006258 Head and Neck Neoplasms Doxorubicin 7.9315692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 7.9315102660 15162350 18337622
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.6620471113
MESH:D006331 Heart Diseases Doxorubicin 3.4818006777 16144979 16495754 16330681 16244372 16244371 17875725 16707910 14766674 18674790 12587719 16879835 17888722
MESH:D006333 Heart Failure Doxorubicin 3.3417481944
MESH:D006394 Hemangiosarcoma Doxorubicin 3.9015692506
MESH:D006432 Hemochromatosis Iron 4.4916574947 17236123 16640825 17053826 16604332 17255318
MESH:D006486 Hemosiderosis Iron 5.2416604332
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.526705139
MESH:D006525 Hepatitis, Viral, Human Iron 5.5016640825
MESH:D006527 Hepatolenticular Degeneration Iron 4.9517182432
MESH:D006529 Hepatomegaly Iron 4.3316890145
MESH:D015658 HIV Infections Iron 3.6716597321
MESH:D006689 Hodgkin Disease Doxorubicin 3.4117606976 15147373 18501091
MESH:D006930 Hyperalgesia Acetaminophen 2.7016870215
MESH:D006943 Hyperglycemia Quercetin 4.0318262572 11834736
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.4617050553
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.9515034207
MESH:D006973 Hypertension Arsenic 5.5816076760 11953799 9931084
MESH:D006973 Hypertension Quercetin 5.5818356687
MESH:D006987 Hypesthesia Arsenic 5.5916093927
MESH:D007006 Hypogonadism Iron 4.4016640825
MESH:D007037 Hypothyroidism Iron 5.0916640825
MESH:D007251 Influenza, Human Quercetin 4.5416624496
MESH:D019189 Iron Metabolism Disorders Iron 5.0417163184
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.059022650 8074119
MESH:D007627 Keloid Quercetin 4.9717086741
MESH:D007642 Keratosis Arsenic 5.0116930632 12749816
MESH:D007674 Kidney Diseases Acetaminophen 10.1512587719 15629191
MESH:D007674 Kidney Diseases Doxorubicin 10.1516775033 15699352 15369732
MESH:D007674 Kidney Diseases Quercetin 10.1516962696
MESH:D007676 Kidney Failure, Chronic Doxorubicin 4.1616707910
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 7.496582329
MESH:D007680 Kidney Neoplasms Fluorouracil 7.4916985049
MESH:D007938 Leukemia Quercetin 3.1617468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.1916085563
MESH:D015470 Leukemia, Myeloid, Acute Vitamin D 3.7920368581
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 3.5517339181
MESH:D020961 Lewy Body Disease Iron 5.4416563566
MESH:D008103 Liver Cirrhosis arsenite 7.1718296743
MESH:D008103 Liver Cirrhosis Iron 7.1716640825
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.209327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 2.7816439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 2.7812741479
MESH:D008107 Liver Diseases Acetaminophen 4.0711587558 12587719 16611625 19784758 16610002 19460945 12969438 19014921
MESH:D008107 Liver Diseases Arsenic 4.0711134558
MESH:D008108 Liver Diseases, Alcoholic Iron 5.0216737972 17207112
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2417185352 16871587
MESH:D008113 Liver Neoplasms Arsenic 14.3016368122
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 14.3020195826 21137059
MESH:D008113 Liver Neoplasms Fluorouracil 14.3018383874 17045692 16603448 15113037
MESH:D008113 Liver Neoplasms Iron 14.3016640825 20302851
MESH:D008113 Liver Neoplasms Quercetin 14.3018980244
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 9.976587162 1399818 3712494 598648
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 9.9717085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Quercetin 9.9719519916
MESH:D008175 Lung Neoplasms Arsenic 10.7319168569 17306315 17976673
MESH:D008175 Lung Neoplasms arsenite 10.7316809336
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 10.7320464547 18520028 20064080 6695378 20869020 17053015 18569708 20135361 18816296
MESH:D008175 Lung Neoplasms Doxorubicin 10.736189445 17418594
MESH:D008175 Lung Neoplasms Fluorouracil 10.7315246190
MESH:D008175 Lung Neoplasms Iron 10.7316640825
MESH:D008175 Lung Neoplasms Quercetin 10.7316280456
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.8115086387
MESH:D008223 Lymphoma Doxorubicin 3.4616098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.7917654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.5815621674
MESH:D008268 Macular Degeneration Iron 3.9816640825
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 3.0315458769
MESH:D008545 Melanoma Doxorubicin 2.2916827129
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5819513568
MESH:D008654 Mesothelioma Doxorubicin 3.0617638057
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.5015792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 8.5416381670
MESH:D009062 Mouth Neoplasms Fluorouracil 8.5416757204 18986760
MESH:D052016 Mucositis Doxorubicin 12.4917415656
MESH:D052016 Mucositis irinotecan 12.4917159606
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 5.7017086897
MESH:D009181 Mycoses Iron 5.5016640825
MESH:D009203 Myocardial Infarction Doxorubicin 6.0319429709 15857846
MESH:D009203 Myocardial Infarction Quercetin 6.0319595682
MESH:D017202 Myocardial Ischemia Arsenic 9.5315371236
MESH:D017202 Myocardial Ischemia Iron 9.5316604332
MESH:D015428 Myocardial Reperfusion Injury Iron 8.9316604332
MESH:D015428 Myocardial Reperfusion Injury Quercetin 8.9319207477
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 9.603581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 9.6018259882
MESH:D009362 Neoplasm Metastasis irinotecan 9.6018259882
MESH:D009369 Neoplasms Benzo(a)pyrene 11.9611141357
MESH:D009369 Neoplasms Fluorouracil 11.9618600527 16928823 18239605
MESH:D009369 Neoplasms Nicotine 11.9616365874
MESH:D009369 Neoplasms Quercetin 11.9615185748
MESH:D009389 Neovascularization, Pathologic arsenite 10.6815738583
MESH:D009389 Neovascularization, Pathologic Nicotine 10.6816365874
MESH:D009401 Nephrosis Doxorubicin 4.7816899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 9.7615640375 16889571
MESH:D009404 Nephrotic Syndrome Iron 9.7617178036
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.386679447
MESH:D009436 Neural Tube Defects Arsenic 7.3816620997
MESH:D009447 Neuroblastoma Doxorubicin 7.1615555623
MESH:D009447 Neuroblastoma irinotecan 7.168761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.5218514411
MESH:D019636 Neurodegenerative Diseases Iron 8.5216604332 17296847
MESH:D017599 Neuroectodermal Tumors irinotecan 4.758761367
MESH:D020078 Neurogenic Inflammation Arsenic 10.7117056641
MESH:D020078 Neurogenic Inflammation Quercetin 10.7117929310
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.4416436463
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.424026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.053988306
MESH:D010003 Osteoarthritis Iron 3.9716640825
MESH:D010024 Osteoporosis Iron 8.0516648989 16640825
MESH:D010024 Osteoporosis Vitamin D 8.0517882678
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.2219495926
MESH:D012516 Osteosarcoma Doxorubicin 4.1115930896
MESH:D010051 Ovarian Neoplasms Arsenic 5.1417306315
MESH:D010051 Ovarian Neoplasms Quercetin 5.1419005980
MESH:D010146 Pain Acetaminophen 2.3916870215
MESH:D010190 Pancreatic Neoplasms Fluorouracil 5.4816500647 15113037 16929163 19003803
MESH:D010190 Pancreatic Neoplasms Quercetin 5.4816965848
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 9.517296757
MESH:D010212 Papilloma Iron 9.5112065085
MESH:D020447 Parasomnias Iron 6.0517352947
MESH:D010300 Parkinson Disease Iron 3.3216640825 16563566
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.1916093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 5.0116905509 6392382 15371236
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.506228378
MESH:D003557 Phyllodes Tumor Doxorubicin 5.1917983394
MESH:D010900 Pituitary Diseases Iron 5.7016604332
MESH:D010997 Pleural Neoplasms Doxorubicin 5.1917638057
MESH:D011041 Poisoning Iron 4.3016604332
MESH:D017119 Porphyria Cutanea Tarda Iron 4.9916640825
MESH:D011230 Precancerous Conditions Quercetin 3.9819056647
MESH:D011225 Pre-Eclampsia Iron 4.4216640825
MESH:D011471 Prostatic Neoplasms Arsenic 1.8816140617
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.8817292933
MESH:D011471 Prostatic Neoplasms Doxorubicin 1.8816868541 15749863 15897917 16888761 18437689 16729912
MESH:D011471 Prostatic Neoplasms Fluorouracil 1.8819082440 18626508
MESH:D011471 Prostatic Neoplasms Quercetin 1.8814715546 17292933
MESH:D011507 Proteinuria Arsenic 4.0121343184
MESH:D011528 Protozoan Infections Iron 6.0516640825
MESH:D012004 Rectal Neoplasms Fluorouracil 4.0118286688 18722050 16160472 15538739
MESH:D051437 Renal Insufficiency Doxorubicin 4.2317922066
MESH:D012148 Restless Legs Syndrome Iron 4.5516930377
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.383692021
MESH:D012509 Sarcoma Doxorubicin 3.9918313854 17203757 17710206 16767912 15625365 15675481
MESH:D012512 Sarcoma, Ewing's Doxorubicin 4.2516326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.8117846226
MESH:D012554 Schistosomiasis japonica Quercetin 5.5816862918
MESH:D012640 Seizures Nicotine 3.8017873105
MESH:D012871 Skin Diseases marker/mechanism 16835338
MESH:D012871 Skin Diseases Arsenic 2.7517050553 16353154 17938729 15952646 17453740 16702368 16759981 6392382 19834688 17548696 18709164
MESH:D012878 Skin Neoplasms Arsenic 13.6617976673 19538983 17029826 16251483 15504454 17050553
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 13.6619755658 10029692
MESH:D012878 Skin Neoplasms Doxorubicin 13.6615692506
MESH:D012878 Skin Neoplasms Iron 13.6612065085
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.5816767912 15625365 17203757
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.442093021 20155912
MESH:D013274 Stomach Neoplasms Fluorouracil 3.4416424979 16951190 15786421 18567086 17522103 19015929 17172411 17498489 19084572 18396642
MESH:D013274 Stomach Neoplasms irinotecan 3.4415723263
MESH:D013398 Sudden Infant Death Iron 5.4716640825
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 7.276582329 3712494 6587162 7505956 1399818
MESH:D013964 Thyroid Neoplasms Doxorubicin 7.2717909728 16010429
OMIM:188890 TOBACCO ADDICTION, SUSCEPTIBILITY TO Nicotine 4.7311259349 16720336 16785264
MESH:D014029 Tobacco Use Disorder Nicotine 5.4615735609 18305452 17979512 18041664
MESH:D014062 Tongue Neoplasms Fluorouracil 3.9916280240
MESH:D014376 Tuberculosis Iron 4.0916597321
MESH:D001749 Urinary Bladder Neoplasms 2-Naphthylamine 19.9311144890
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 19.938074119
MESH:D001749 Urinary Bladder Neoplasms Arsenic 19.9317976673 19429237 18640142 15987713 17306315 19322015 11144890
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 19.9317053015
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 19.9317653716
MESH:D001749 Urinary Bladder Neoplasms Quercetin 19.9316720314
MESH:D014581 Urticaria Acetaminophen 2.9810982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 3.8816803524
MESH:D014652 Vascular Diseases Arsenic 4.7517056641
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.2317638931 17334414 17678736 16364871
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA34361
    • No data
    Releated disease ID Related disease Name
    PA443652Celiac Disease
    PA443888Diabetes Mellitus, Type 1
    PA443652Celiac Disease
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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