AutismKB 2.0

Annotation Detail for RGS2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RGS2 ( G0S8 )
Gene Full Name: regulator of G-protein signaling 2, 24kDa
Band: 1q31.2
Quick LinksEntrez ID:5997; OMIM: 600861; Uniprot ID:RGS2_HUMAN; ENSEMBL ID: ENSG00000116741; HGNC ID: 9998
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
P00026Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
P00027Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1790Hyperaldosteronism
1944Breast cancer
2091Hypertension
2069Schizophrenia
Desease Name
suicidal ideation
PSYCH
extrapyramidal side effects
PHARMACOGENOMIC
metabolic syndrome
METABOLIC
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C061282 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of RGS2 mRNA]decreases reaction|increases expression 15452191
D000082 Acetaminophen Acetaminophen affects the expression of RGS2 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of RGS2 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RGS2 mRNAaffects expression 16483693
D014150 Antipsychotic Agents RGS2 3' UTR polymorphism affects the susceptibility to Antipsychotic Agentsaffects response to substance 18347610
C058317 arsenic disulfide arsenic disulfide results in decreased expression of RGS2 mRNAdecreases expression 12890387
C006632 arsenic trioxide arsenic trioxide results in decreased expression of RGS2 mRNAdecreases expression 12852829
20458559
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of RGS2 mRNAincreases expression 18687144
D001554 Benzene Benzene results in decreased expression of RGS2 mRNAdecreases expression 15120971
15122651
C005961 bis(tri-n-butyltin)oxide bis(tri-n-butyltin)oxide results in increased expression of RGS2 mRNAincreases expression 17553608
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of RGS2 mRNAincreases expression 15336504
D015762 2-Chloroadenosine 2-Chloroadenosine inhibits the reaction [Phenylephrine results in increased expression of RGS2 mRNA]decreases reaction|increases expression 15452191
C014347 decitabine [decitabine co-treated with vorinostat] affects the expression of RGS2 mRNAaffects cotreatment|affects expression 17330099
C014347 decitabine decitabine results in increased expression of RGS2 mRNAincreases expression 16367923
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of RGS2 mRNAaffects cotreatment|increases expression 16054899
D004041 Dietary Fats Dietary Fats results in decreased expression of RGS2 mRNAdecreases expression 18042831
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of RGS2 mRNAincreases expression 19638242
D004958 Estradiol Estradiol results in increased expression of RGS2 mRNAincreases expression 20106945
D004958 Estradiol [Progesterone co-treated with Estradiol] results in increased expression of RGS2 mRNAaffects cotreatment|increases expression 17404688
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of RGS2 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RGS2 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of RGS2 mRNAdecreases expression 17351261
D005038 Ethylnitrosourea Ethylnitrosourea results in increased mutagenesis of RGS2 geneincreases mutagenesis 16724327
D005419 Flavonoids Flavonoids results in increased expression of RGS2 mRNAincreases expression 18035473
D005472 Fluorouracil Fluorouracil results in decreased expression of RGS2 mRNAdecreases expression 16510598
C056507 gemcitabine gemcitabine results in increased expression of RGS2 mRNAincreases expression 17039268
D006220 Haloperidol Haloperidol results in increased expression of RGS2 mRNAincreases expression 11409749
11516571
D007501 Iron Iron deficiency results in increased expression of RGS2 mRNAincreases expression 20368581
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of RGS2 mRNAaffects cotreatment|increases expression 16054899
D008345 Manganese Manganese results in increased expression of RGS2 mRNAincreases expression 17175027
C025340 manganese chloride manganese chloride results in increased expression of RGS2 mRNAincreases expression 17175027
D008942 Mitoxantrone RGS2 protein affects the susceptibility to Mitoxantroneaffects response to substance 16217747
C084956 N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of RGS2 mRNA]decreases reaction|increases expression 15452191
C048599 N(6)-cyclopentyladenosine N(6)-cyclopentyladenosine inhibits the reaction [Phenylephrine results in increased expression of RGS2 mRNA]decreases reaction|increases expression 15452191
C041786 palm oil palm oil results in decreased expression of RGS2 mRNAdecreases expression 18042831
D010656 Phenylephrine RGS2 protein affects the susceptibility to Phenylephrineaffects response to substance 17644703
D010656 Phenylephrine 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of RGS2 mRNA]decreases reaction|increases expression 15452191
D010656 Phenylephrine 2-Chloroadenosine inhibits the reaction [Phenylephrine results in increased expression of RGS2 mRNA]decreases reaction|increases expression 15452191
D010656 Phenylephrine N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of RGS2 mRNA]decreases reaction|increases expression 15452191
D010656 Phenylephrine N(6)-cyclopentyladenosine inhibits the reaction [Phenylephrine results in increased expression of RGS2 mRNA]decreases reaction|increases expression 15452191
D010656 Phenylephrine Phenylephrine results in increased expression of RGS2 mRNAincreases expression 15452191
18158353
16517124
D010656 Phenylephrine RGS2 protein inhibits the reaction [Phenylephrine results in increased expression of ACTA1 mRNA]decreases reaction|increases expression 16517124
D010656 Phenylephrine RGS2 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]decreases reaction|increases expression 16517124
D010656 Phenylephrine RGS2 protein inhibits the reaction [Phenylephrine results in increased expression of SLC9A1 mRNA]decreases reaction|increases expression 16517124
D010656 Phenylephrine RGS2 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]decreases reaction|increases activity|increases phosphorylation 16517124
D010656 Phenylephrine RGS2 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]decreases reaction|increases activity|increases phosphorylation 16517124
D010656 Phenylephrine RGS2 protein promotes the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK8 protein]increases activity|increases phosphorylation|increases reaction 16517124
D011374 Progesterone [Progesterone co-treated with Estradiol] results in increased expression of RGS2 mRNAaffects cotreatment|increases expression 17404688
D011374 Progesterone Progesterone results in increased expression of RGS2 mRNAincreases expression 18070364
17404688
D011374 Progesterone Progesterone affects the expression of RGS2 mRNAaffects expression 17251523
D017378 Quinolinic Acid Quinolinic Acid results in decreased expression of RGS2 mRNAdecreases expression 12207953
D017378 Quinolinic Acid Quinolinic Acid results in decreased expression of RGS2 proteindecreases expression 12207953
D018967 Risperidone Risperidone results in increased expression of RGS2 mRNAincreases expression 11516571
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of RGS2 mRNAaffects cotreatment|increases expression 16054899
C410733 scriptaid scriptaid affects the expression of RGS2 mRNAaffects expression 18813790
C017947 sodium arsenite sodium arsenite results in decreased expression of RGS2 mRNAdecreases expression 18812580
C017947 sodium arsenite sodium arsenite results in increased expression of RGS2 mRNAincreases expression 16014739
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of RGS2 mRNAdecreases expression 16443690
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of RGS2 mRNAdecreases expression 17101203
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RGS2 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of RGS2 mRNAdecreases expression 15652763
C024746 tobacco tar tobacco tar results in decreased expression of RGS2 mRNAdecreases expression 19559774
C496197 trans-10,cis-12-conjugated linoleic acid trans-10,cis-12-conjugated linoleic acid results in increased expression of RGS2 mRNAincreases expression 17951470
C034028 vanadyl sulfate vanadyl sulfate results in increased expression of RGS2 mRNAincreases expression 16330358
D014810 Vitamin E Vitamin E results in increased expression of RGS2 mRNAincreases expression 19244175
C111237 vorinostat [decitabine co-treated with vorinostat] affects the expression of RGS2 mRNAaffects cotreatment|affects expression 17330099
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.3914514962 15322242 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.1018287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.4717505938
MESH:D000230 Adenocarcinoma arsenic trioxide 9.0111798837 19825857
MESH:D000230 Adenocarcinoma Estradiol 9.0111473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 9.0114692618
MESH:D000230 Adenocarcinoma Fluorouracil 9.0117638652
MESH:D000236 Adenoma Diethylnitrosamine 6.0910737359 6695378
MESH:D000236 Adenoma Ethylnitrosourea 6.096695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 8.5117620307 19052882 17162532 19061943 16434500 18056438
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.5116835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.2215276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.4317306315 16712894
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 5.1916640825
MESH:D000544 Alzheimer Disease Iron 4.2716640825 16563566
MESH:D000544 Alzheimer Disease rosiglitazone 4.2719621015
MESH:D000740 Anemia Fluorouracil 12.5616511603 15504547 17963324
MESH:D000740 Anemia Iron 12.5616566752 16434484
MESH:D000740 Anemia Tetrachlorodibenzodioxin 12.5611748828
MESH:D000741 Anemia, Aplastic Benzene 4.0111369114 17661222 14761424
MESH:D018798 Anemia, Iron-Deficiency Iron 4.2416569441 17375513 17163184 17162259 17147795
MESH:D000756 Anemia, Sideroblastic Iron 15.4916910769
MESH:D000756 Anemia, Sideroblastic Manganese 15.4916910769
MESH:D000756 Anemia, Sideroblastic manganese chloride 15.4916910769
MESH:D000799 Angioedema Acetaminophen 3.3710982225
MESH:D001145 Arrhythmias, Cardiac Iron 8.0116604332
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 8.0117460149
MESH:D001161 Arteriosclerosis Dietary Fats 8.4015238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 8.4011256880
MESH:D001169 Arthritis, Experimental Dexamethasone 6.3917659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.3915885639
MESH:D020817 Asperger Syndrome Risperidone 5.1016401163
MESH:D001260 Ataxia Telangiectasia Iron 4.9815336622
MESH:D050197 Atherosclerosis Iron 3.4316640825 16632123
MESH:D001289 Attention Deficit Disorder with Hyperactivity Risperidone 4.4718349709
MESH:D001321 Autistic Disorder Acetaminophen 4.2718445737
MESH:D001321 Autistic Disorder Antipsychotic Agents 4.2717630868 17929164
MESH:D001321 Autistic Disorder Haloperidol 4.2719368416 18080171
MESH:D001321 Autistic Disorder Iron 4.2717352947
MESH:D001321 Autistic Disorder Quinolinic Acid 4.2716139734
MESH:D001321 Autistic Disorder Risperidone 4.2717019624 16379507 15543515 19368416 15930063 19013209 16730335 16948927 15994720 16239862 19232924 17069546 18775368 18026891 18080171 17929164 16601648 19154706 18278980 18349709 15492353
MESH:D001424 Bacterial Infections Iron 4.7316640825
MESH:D001714 Bipolar Disorder Risperidone 4.2719154706 18278980
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 7.5816206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 7.5812125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4615746008
MESH:D001855 Bone Marrow Diseases Benzene 4.7616183116
MESH:D001919 Bradycardia Phenylephrine 4.0815306635
MESH:D001927 Brain Diseases Ethylnitrosourea 4.4814991843
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.8617868700
MESH:D001930 Brain Injuries Progesterone 3.8015665606 15845082 15380490
MESH:D001932 Brain Neoplasms Ethylnitrosourea 3.8915144691 18412241 16651633 16436596 16357521
MESH:D001943 Breast Neoplasms marker/mechanism 16298037
MESH:D001943 Breast Neoplasms Benzene 6.3717162533 11921183
MESH:D001943 Breast Neoplasms decitabine 6.3719208741 18320071
MESH:D001943 Breast Neoplasms Dietary Fats 6.3720435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 6.3717474063
MESH:D001943 Breast Neoplasms Estradiol 6.3717289903 16675129 17261762 12948864 19861407 14630087 18497071 17018787
MESH:D001943 Breast Neoplasms Fluorouracil 6.3718357371 16595493 15136595 16557594 16110121 18608205 19217205
MESH:D001943 Breast Neoplasms gemcitabine 6.3717039268 18382427
MESH:D001943 Breast Neoplasms Progesterone 6.3715562024 17614352 16175315
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 6.3720435547
MESH:D001943 Breast Neoplasms vorinostat 6.3716144943
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.9011589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0016111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.4816050911
MESH:D002276 Carcinoid Tumor Fluorouracil 4.1916051944
MESH:D002277 Carcinoma Fluorouracil 6.9617121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.9616835633
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 12.643084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 12.6412907637 12619106 21507988
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 12.6414691202 15553829 16217749 15073043 11135700
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 12.6420432363 3084413 10737359 20935162 18494052 20084675 16328049 16830150 17761372 19335982 19171122 19519916 17138121 16540662 18056438 3581430 20514400 19822196 18665156 11831363 18978308 19394651 19208518 16779866 17162532 19539802 16502159 20007298 16878318 18785209 17055752 18210153 19107877 16807293 18971187 20524982 20101231 19052882 18393292 19701751 16681979 17428255 18506893 16698587 20727157 21159647 19383236 17978847 16569478 18691550 10672840 20512989 18788625 19919837 19418558 16288022 17173139 16935385 20214788
MESH:D006528 Carcinoma, Hepatocellular Estradiol 12.6416924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 12.6417045692 17971768 16799960 18930000 17088986 16332177
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 12.6417306315 16507464 15276417
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.4019014326
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.7918695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.7112490120
MESH:D002294 Carcinoma, Squamous Cell decitabine 6.6919215824
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 6.6917066447 16280240 16757204 18986760
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 6.6918572023
MESH:D006332 Cardiomegaly Phenylephrine 5.9817124262 11754973 11179087 15728586 16170337 17287366
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.9818850075 18670907 16120746
MESH:D009202 Cardiomyopathies Iron 3.7316640825
MESH:D002311 Cardiomyopathy, Dilated Iron 3.2916604332
MESH:D002375 Catalepsy Haloperidol 4.4515215559 1977408
MESH:D002386 Cataract Acetaminophen 2.3010977129
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 17.6721159647 7505956 2727394 17174075
MESH:D002471 Cell Transformation, Neoplastic Estradiol 17.6718566989
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 17.6716003739
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 17.6719524636 20056578
MESH:D002471 Cell Transformation, Neoplastic tobacco tar 17.6719559774
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 5.5117160924
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.0219052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.0216835633
MESH:D002779 Cholestasis Ethinyl Estradiol 2.5317681005 16105132 17333356 16919318 11677210 17110522 15861022
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.9015340226 15668235 12621046 8697196 16354765
MESH:D003110 Colonic Neoplasms decitabine 7.4717616700
MESH:D003110 Colonic Neoplasms Dexamethasone 7.4715824018
MESH:D003110 Colonic Neoplasms Fluorouracil 7.4717016597 16510598 17287894 15001691 17018589 17725105 16340194 17172411 18772588 17169374
MESH:D003110 Colonic Neoplasms Iron 7.4716640825
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.1820501625
MESH:D015179 Colorectal Neoplasms decitabine 3.1818981723
MESH:D015179 Colorectal Neoplasms Fluorouracil 3.1818949393 20501625 14970324 18448328 15289873 16282729 17255274 16391804 17094418 16524972 17594712 18383874 17016601 18509181 16331619 16303861 18288408 17401013 18802399 15148649 17454858 17695437
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.6717141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 3.7412609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 6.6410525206
MESH:D019465 Craniofacial Abnormalities Benzene 6.6415643154
MESH:D019465 Craniofacial Abnormalities Dexamethasone 6.6417728286
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 6.6410048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Vitamin E 6.6419769572
MESH:D007644 Darier Disease Fluorouracil 4.3316733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 15.8715213294
MESH:D016757 Death, Sudden, Cardiac Haloperidol 15.8720210726
MESH:D016757 Death, Sudden, Cardiac Risperidone 15.8720210726
MESH:D003704 Dementia Haloperidol 9.1711575062
MESH:D003704 Dementia Risperidone 9.1711575062
MESH:D003872 Dermatitis Benzene 4.3115902427
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 2.9812438553
MESH:D003920 Diabetes Mellitus Iron 8.3716640825 16604332
MESH:D003920 Diabetes Mellitus rosiglitazone 8.3717446233
MESH:D003921 Diabetes Mellitus, Experimental vanadyl sulfate 4.0016684804
MESH:D003922 Diabetes Mellitus, Type 1 Iron 3.2016506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 9.1620387270
MESH:D003924 Diabetes Mellitus, Type 2 Iron 9.1616506275
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 9.1612642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 9.1617107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.0219279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.0417187935
MESH:D003967 Diarrhea Dexamethasone 7.087237001
MESH:D003967 Diarrhea vorinostat 7.0820479100
MESH:D006970 Disorders of Excessive Somnolence Risperidone 5.8516379507
MESH:D053207 Diurnal Enuresis Risperidone 6.2017822346
MESH:D004314 Down Syndrome Risperidone 4.7318349709
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 5.2111461765 16081117 19416960 14986274 12392966 19085960 10915739 16109766 10663392 17522070 11529661 11834606 16393943 19164858 11739529 12958197 11743745 2444490 11287661 16227642 19739265 19923254 12705907 17906064 18713872 11421492 16485898 16177239 10774834 15968718 17562736 12594235 14550746 16781746 19370779 18071297 19420014 15619225 14725611 12153990 12540782
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 5.2119107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 5.2120420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6219426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.4111462148
MESH:D004409 Dyskinesia, Drug-Induced Antipsychotic Agents 6.153690436
MESH:D050171 Dyslipidemias Dietary Fats 3.1118367378
MESH:C538011 Eales disease Vitamin E 4.239068938
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 5.5118357618
MESH:D004485 Eczema Dexamethasone 4.0212438553
MESH:D004487 Edema Dexamethasone 9.2219703484
MESH:D004487 Edema rosiglitazone 9.2212083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 9.2211000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.4316714409 18230668 15322242
MESH:D020803 Encephalitis, Herpes Simplex Quinolinic Acid 6.3417174341
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 7.5712538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 7.5717692515
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.6419294695
MESH:D016889 Endometrial Neoplasms Estradiol 2.6711473722 18566989 19148513
MESH:D004715 Endometriosis Progesterone 7.5916134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.5910568697 9294722
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6416302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.1312903497
MESH:D004938 Esophageal Neoplasms Fluorouracil 4.1317638652 15173087 16481741 16337965 16785472
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.6611564622
MESH:D005221 Fatigue vorinostat 5.1320479100
MESH:D005234 Fatty Liver arsenic trioxide 25.3415073043
MESH:D005234 Fatty Liver Dietary Fats 25.3419004024 18296743 19551842 17967931
MESH:D005234 Fatty Liver Diethylnitrosamine 25.3420387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 25.3415345470
MESH:D005234 Fatty Liver Iron 25.3416640825
MESH:D005234 Fatty Liver rosiglitazone 25.3419196556
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0011858732
MESH:D005355 Fibrosis Dietary Fats 7.1218296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 7.1220067830
MESH:D005621 Friedreich Ataxia Iron 4.9716604332 16640825
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.8216904648
MESH:D005756 Gastritis Acetaminophen 3.2016983495
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.2116452187
MESH:D005909 Glioblastoma Ethylnitrosourea 6.7216436596
MESH:D005909 Glioblastoma Manganese 6.7217043766
MESH:D005910 Glioma Ethylnitrosourea 5.6718412241 16651633 16357521
MESH:D005910 Glioma Fluorouracil 5.6716145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1210696789
MESH:D006258 Head and Neck Neoplasms decitabine 6.8419215824
MESH:D006258 Head and Neck Neoplasms Fluorouracil 6.8415162350 15102660 18337622
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.7110048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 5.7116080930
MESH:D006331 Heart Diseases Mitoxantrone 3.8316019553
MESH:D006402 Hematologic Diseases Benzene 4.2216183116
MESH:D006432 Hemochromatosis Iron 4.1516604332 16640825 17236123 16574947 17255318 17053826
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9211000095
MESH:D006486 Hemosiderosis Iron 4.7416604332
MESH:D006525 Hepatitis, Viral, Human Iron 4.9916640825
MESH:D006527 Hepatolenticular Degeneration Iron 4.4817182432
MESH:D006529 Hepatomegaly Iron 7.2516890145
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.2515340226 16120746 12621046
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 5.377520565
MESH:D006548 Hernia, Diaphragmatic Vitamin E 5.3716863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 4.5615709030
MESH:D015658 HIV Infections Iron 3.4216597321
MESH:D006689 Hodgkin Disease sodium arsenite 2.7712676792
MESH:D019584 Hot Flashes Estradiol 8.4717088409
MESH:D019584 Hot Flashes Vitamin E 8.4714716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.578697196 18606429 15340226 16959395 16354765
MESH:D006930 Hyperalgesia Acetaminophen 6.6716870215
MESH:D006930 Hyperalgesia rosiglitazone 6.6712083418
MESH:D006937 Hypercholesterolemia Dietary Fats 3.1821332399
MESH:D006943 Hyperglycemia Risperidone 4.7618278980
MESH:D006949 Hyperlipidemias Dietary Fats 3.1921332399
MESH:D006973 Hypertension Benzene 10.8117940673
MESH:D006973 Hypertension Dexamethasone 10.8117042910
MESH:D006973 Hypertension Phenylephrine 10.8112717712 8949925
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 10.8118670907 18850075
MESH:D006984 Hypertrophy Phenylephrine 4.1418502941 12791704
MESH:D007006 Hypogonadism Iron 4.0716640825
MESH:D007021 Hypospadias Ethinyl Estradiol 3.3616945680 16569931
MESH:D007037 Hypothyroidism Iron 4.6316640825
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 4.9718306037
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.9515869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.0312013081
MESH:D007248 Infertility, Male decitabine 9.3917581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 9.3917937319
MESH:D007248 Infertility, Male sodium arsenite 9.3915346721 12646999
MESH:D007249 Inflammation Dexamethasone 20.2911099482 8960868
MESH:D007249 Inflammation Dietary Fats 20.2920412841
MESH:D007249 Inflammation Diethylnitrosamine 20.2918785209
MESH:D007249 Inflammation Flavonoids 20.2917296493
MESH:D007249 Inflammation Progesterone 20.2915869954
MESH:D007249 Inflammation rosiglitazone 20.2912083418
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 20.2912200463 12878042
MESH:D007251 Influenza, Human Vitamin E 3.7416624496
MESH:D007333 Insulin Resistance Dietary Fats 10.6411836018 18457598
MESH:D007333 Insulin Resistance Estradiol 10.6416393666 16627594
MESH:D007333 Insulin Resistance rosiglitazone 10.6416306350
MESH:D019189 Iron Metabolism Disorders Iron 4.6117163184
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.9216580747
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 4.9718306037
MESH:D007674 Kidney Diseases Acetaminophen 12.1312587719 15629191
MESH:D007674 Kidney Diseases Estradiol 12.1315618244
MESH:D007674 Kidney Diseases sodium arsenite 12.1320008137
MESH:D007674 Kidney Diseases Vitamin E 12.1312488133
MESH:D007680 Kidney Neoplasms Estradiol 10.3915610895
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 10.3917379185
MESH:D007680 Kidney Neoplasms Fluorouracil 10.3916985049
MESH:D007938 Leukemia arsenic trioxide 9.1515070760
MESH:D007938 Leukemia Benzene 9.1515935818 18335105 17119257 14694614
MESH:D007938 Leukemia decitabine 9.1519235587 18980019
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Mitoxantrone 3.5818172266
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.3812560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.8416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic disulfide 7.7612421474
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 7.7614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 13.6819077051
MESH:D007951 Leukemia, Myeloid Benzene 13.6817506065
MESH:D007951 Leukemia, Myeloid decitabine 13.6817236224 18454857 19117987
MESH:D015470 Leukemia, Myeloid, Acute marker/mechanism 17330099
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 5.6116467208 20471514 19850784 17050201 16968895
MESH:D015470 Leukemia, Myeloid, Acute Benzene 5.6119478238
MESH:D015470 Leukemia, Myeloid, Acute decitabine 5.6118206229 17679729 19387464 18460780 19010910 18704418
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.9918055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 2.9016823087 16891316 19035177 16966277 11468182 17869043 17649720 11161223 17107899 19075265 12712474 15336539 12018890 15213294 9834237 15622746 19642359 12679006 15748426 16330433 16112521 19225113 17712046 17217047 16331271
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.9116882451
MESH:D020961 Lewy Body Disease Iron 4.9716563566
MESH:D008103 Liver Cirrhosis Dietary Fats 9.5718296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 9.5720032147 19638242 18522880 18407596 18665156
MESH:D008103 Liver Cirrhosis Iron 9.5716640825
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 5.9916718785
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 5.9914716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 5.9915980055 17347453
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 5.9912878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 5.9916169303
MESH:D008107 Liver Diseases Acetaminophen 3.4416610002 19784758 11587558 12969438 19014921 16611625 19460945 12587719
MESH:D008107 Liver Diseases Diethylnitrosamine 3.4417034775
MESH:D008108 Liver Diseases, Alcoholic Iron 4.5516737972 17207112
MESH:D017114 Liver Failure, Acute Acetaminophen 2.8317185352 16871587
MESH:D008113 Liver Neoplasms Aflatoxin B1 18.872125692 18177683 15890375 9163691
MESH:D008113 Liver Neoplasms arsenic trioxide 18.8714682389
MESH:D008113 Liver Neoplasms Diethylnitrosamine 18.8718648771 19426721 15175105 19256749 20118626 20405173 18978307 19690152 20137499 21071580 15885732 18754104 19254457 19642983 19499222 21047994 19850985 20583210 12771043 20492335 20452335 21167192 20501860 16942905 2862719 19996281 2422723 19427195 21278145 19833225 19551842 9163691 18977376 19255062 20434301 18644402 19812893 19073162 12112319 10737359 19294768 19090486 20101389 19638242
MESH:D008113 Liver Neoplasms Fluorouracil 18.8715113037 17045692 16603448 18383874
MESH:D008113 Liver Neoplasms Iron 18.8720302851 16640825
MESH:D008113 Liver Neoplasms sodium arsenite 18.8715276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 18.8716984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 15.478603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 15.4720377131
MESH:D008114 Liver Neoplasms, Experimental Benzene 15.4712562636
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 15.4719009564 18253720 21159647 18282651 2563599 19519916 16842330 19126423 18079962 18093689 16267830 17942915 19539802 18308698 18775883 18164116 9362446 3124819 18544905 17854601 19004024 17174075
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 15.4712151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.0015213294
MESH:D008171 Lung Diseases sodium arsenite 6.3819095001
MESH:D008171 Lung Diseases Vitamin E 6.3816863852
MESH:D017563 Lung Diseases, Interstitial Benzene 4.3314698565
MESH:D055370 Lung Injury Asbestos, Crocidolite 3.5717365036
MESH:D008175 Lung Neoplasms Aflatoxin B1 18.8014755239
MESH:D008175 Lung Neoplasms arsenic trioxide 18.8011798837 19825857
MESH:D008175 Lung Neoplasms Benzene 18.8012562636
MESH:D008175 Lung Neoplasms Dexamethasone 18.8011195469 15824018
MESH:D008175 Lung Neoplasms Diethylnitrosamine 18.8020970405 20512841 6695378 21163286
MESH:D008175 Lung Neoplasms Ethylnitrosourea 18.8016019985 16271038 6695378 17703301
MESH:D008175 Lung Neoplasms Fluorouracil 18.8015246190
MESH:D008175 Lung Neoplasms Iron 18.8016640825
MESH:D008175 Lung Neoplasms sodium arsenite 18.8015276417 19931552 17077188 16712894 17306315
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 18.8019555203 11884234
MESH:D008175 Lung Neoplasms Vitamin E 18.8011062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.3315086387
MESH:D008223 Lymphoma Benzene 10.7817584886 17119257
MESH:D008223 Lymphoma decitabine 10.7819470736
MESH:D008223 Lymphoma Ethylnitrosourea 10.7815790496
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 4.5915375218
MESH:D016410 Lymphoma, T-Cell, Cutaneous vorinostat 5.2320479100
MESH:D008268 Macular Degeneration Iron 3.7116640825
MESH:D015674 Mammary Neoplasms, Animal Benzene 3.9812562636
MESH:D008325 Mammary Neoplasms, Experimental Benzene 15.5911921183
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 15.5911807958 11408345 17203775 16891317
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 15.5918041768 10838139 10767621
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 15.5917203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 15.5916827153
MESH:D020149 Manganese Poisoning Estradiol 11.4219453300
MESH:D020149 Manganese Poisoning Manganese 11.4219453300 16568477 16551646
MESH:D008545 Melanoma decitabine 3.1417785578 16505122
MESH:D008545 Melanoma sodium arsenite 3.1419082730 16487513
MESH:D008546 Melanoma, Experimental Acetaminophen 3.1119513568
MESH:D008579 Meningioma Ethylnitrosourea 5.5117943659
MESH:D001523 Mental Disorders Haloperidol 7.1216856516
MESH:D001523 Mental Disorders Risperidone 7.1216596465 16856516
MESH:D008607 Mental Retardation Risperidone 3.9418349709
MESH:D008654 Mesothelioma Asbestos, Crocidolite 2.9816966607 18303189 16166281
MESH:D024821 Metabolic Syndrome X Antipsychotic Agents 14.2017632216
MESH:D024821 Metabolic Syndrome X Risperidone 14.2019142101
MESH:D024821 Metabolic Syndrome X rosiglitazone 14.2017261469
MESH:D019964 Mood Disorders Risperidone 5.3817019624
MESH:D009062 Mouth Neoplasms Fluorouracil 3.2716757204 18986760
MESH:D009069 Movement Disorders Manganese 4.5816551646
MESH:D009101 Multiple Myeloma arsenic trioxide 14.5514977855 19417148 11468182 15949261 19549372
MESH:D009101 Multiple Myeloma Benzene 14.5517119195
MESH:D009101 Multiple Myeloma decitabine 14.5518172295
MESH:D009101 Multiple Myeloma Dexamethasone 14.5516118317 15867202 15744524
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 5.2017086897
MESH:D009181 Mycoses Iron 4.9916640825
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.2018349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 10.7916105982 16882451
MESH:D009190 Myelodysplastic Syndromes decitabine 10.7918608210 19157545 19010910 16882708
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 10.799809623
MESH:D017202 Myocardial Ischemia Iron 7.9416604332
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 7.9412213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.5416810080
MESH:D015428 Myocardial Reperfusion Injury Iron 7.5416604332
MESH:D009325 Nausea vorinostat 5.0520479100
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.5216624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.379029167 3581430
MESH:D009369 Neoplasms decitabine 9.9219470736 17925555 19116145
MESH:D009369 Neoplasms Fluorouracil 9.9216928823 18239605 18600527
MESH:D009369 Neoplasms Mitoxantrone 9.9216640825
MESH:D009369 Neoplasms sodium arsenite 9.9211559025
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 7.8716707424
MESH:D009374 Neoplasms, Experimental sodium arsenite 7.8720056578
MESH:D009389 Neovascularization, Pathologic Estradiol 3.2717289903
MESH:D009404 Nephrotic Syndrome Iron 4.1217178036
MESH:D009410 Nerve Degeneration Manganese 3.9216551646
MESH:D009421 Nervous System Malformations Estradiol 8.0016427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.0014600291
MESH:D009436 Neural Tube Defects arsenic trioxide 10.4310525206
MESH:D009436 Neural Tube Defects Benzene 10.4315643154
MESH:D009436 Neural Tube Defects sodium arsenite 10.4312854658
MESH:D009442 Neurilemmoma Ethylnitrosourea 4.9517160924 16003739 16651423
MESH:D019636 Neurodegenerative Diseases Acetaminophen 11.9218514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 11.9220387270
MESH:D019636 Neurodegenerative Diseases Iron 11.9217296847 16604332
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6420387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.1216436463
MESH:D053206 Nocturnal Enuresis Risperidone 5.8517822346
MESH:D009765 Obesity Dietary Fats 2.1618674790 21332399 19632207 20518802 16723640 18457598 20132043 17217161 11836018
MESH:D009784 Occupational Diseases Benzene 3.7817178637 15612468 17119257 15935809 17479406 15727169 16737584 15576619 15913788
MESH:D009837 Oligodendroglioma Ethylnitrosourea 5.5117160924
MESH:D010003 Osteoarthritis Iron 3.6816640825
MESH:D010024 Osteoporosis Iron 3.5716648989 16640825
MESH:D010051 Ovarian Neoplasms arsenic trioxide 16.6816624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Benzene 16.6812562636
MESH:D010051 Ovarian Neoplasms decitabine 16.6819331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 16.6819401270
MESH:D010051 Ovarian Neoplasms Progesterone 16.6816525653 17393432
MESH:D010051 Ovarian Neoplasms sodium arsenite 16.6817306315 15276417
MESH:D010146 Pain Acetaminophen 2.0316870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 14.3315580305
MESH:D010190 Pancreatic Neoplasms decitabine 14.3319294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 14.3316540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 14.3316500647 16929163 15113037 19003803
MESH:D010190 Pancreatic Neoplasms gemcitabine 14.3311504793 17440100 16929163 18383843 18992248
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2611578682
MESH:D010212 Papilloma Iron 4.0312065085
MESH:D010235 Paraganglioma arsenic trioxide 3.7319927285
MESH:D020447 Parasomnias Iron 5.5417352947
MESH:D010300 Parkinson Disease Iron 5.2716640825 16563566
MESH:D010300 Parkinson Disease Manganese 5.2711181820
MESH:D010302 Parkinson Disease, Secondary marker/mechanism 18347610
MESH:D010302 Parkinson Disease, Secondary Antipsychotic Agents 5.9918347610
MESH:D020734 Parkinsonian Disorders Manganese 4.0716140633
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.7712520081
MESH:D010900 Pituitary Diseases Iron 5.2016604332
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.4410923243
MESH:D011041 Poisoning Iron 8.3616604332
MESH:D011041 Poisoning N(6)-cyclopentyladenosine 8.3616105447
MESH:D017119 Porphyria Cutanea Tarda Iron 9.5516640825
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 9.5518163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.162563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.2721297632
MESH:D011225 Pre-Eclampsia Iron 4.0616640825
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.7311118676 11222880 11896295 11399792
MESH:D055728 Primary Myelofibrosis decitabine 4.2717616702
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.4720887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.8719131511
MESH:D011471 Prostatic Neoplasms Estradiol 1.8716740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 1.8718626508 19082440
MESH:D011471 Prostatic Neoplasms sodium arsenite 1.8716039940
MESH:D011471 Prostatic Neoplasms Vitamin E 1.8715084515
MESH:D011471 Prostatic Neoplasms vorinostat 1.8717218635
MESH:D011528 Protozoan Infections Iron 5.5416640825
MESH:D011537 Pruritus Ethinyl Estradiol 2.8516919318 15861022
MESH:D011595 Psychomotor Agitation Haloperidol 4.5011575062
MESH:D011618 Psychotic Disorders Haloperidol 3.9111575062
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 2.8417365031 17322281 15814490 17975199
MESH:D012004 Rectal Neoplasms Fluorouracil 3.6218722050 18286688 16160472 15538739
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 3.5911700416 18379247
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.3918990726
MESH:D012148 Restless Legs Syndrome Iron 4.2016930377
MESH:D012208 Rhabdomyosarcoma decitabine 3.9719155313
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.6818045962
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.5216646077
MESH:D012559 Schizophrenia Haloperidol 4.1020107430 19369910 1830565 18513383
MESH:D012559 Schizophrenia Risperidone 4.1020107430 19154706 18278980
MESH:D012852 Sinusitis Phenylephrine 4.247327846
MESH:D012871 Skin Diseases Vitamin E 2.3118709164
MESH:D012878 Skin Neoplasms Iron 11.6512065085
MESH:D012878 Skin Neoplasms sodium arsenite 11.6519524636 18572023
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 11.658532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 11.6516192470
MESH:D012893 Sleep Disorders Risperidone 5.0418278980
MESH:D013088 Spermatocele Ethinyl Estradiol 3.4716709447
MESH:D013119 Spinal Cord Injuries Progesterone 3.8216503802 15862959
MESH:D016135 Spinal Dysraphism sodium arsenite 3.4412854658
MESH:D013272 Stomach Diseases Dexamethasone 3.8615472012
MESH:D013274 Stomach Neoplasms marker/mechanism 16367923
MESH:D013274 Stomach Neoplasms arsenic trioxide 5.7717007042
MESH:D013274 Stomach Neoplasms Benzene 5.7712562636
MESH:D013274 Stomach Neoplasms decitabine 5.7719037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 5.7718456281
MESH:D013274 Stomach Neoplasms Fluorouracil 5.7718396642 17172411 16424979 17498489 18567086 15786421 19015929 16951190 17522103 19084572
MESH:D013276 Stomach Ulcer Dexamethasone 3.0915138204
MESH:D020521 Stroke Vitamin E 3.1516517955
MESH:D013398 Sudden Infant Death Iron 4.9816640825
MESH:D017180 Tachycardia, Ventricular Haloperidol 9.5220210726
MESH:D017180 Tachycardia, Ventricular Risperidone 9.5220210726
MESH:D013921 Thrombocytopenia vorinostat 4.5720479100
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.1911994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7615669648
MESH:D013953 Thymus Neoplasms Benzene 10.6510850423
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 10.6515790496
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4312697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 9.9619014326
MESH:D013964 Thyroid Neoplasms decitabine 9.9617967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 9.967505956
MESH:D013978 Tibial Fractures Estradiol 4.2119048282
MESH:D014062 Tongue Neoplasms Fluorouracil 3.5916280240
MESH:D016171 Torsades de Pointes arsenic trioxide 3.5015213294
MESH:D005879 Tourette Syndrome Risperidone 5.4919154706
MESH:D014376 Tuberculosis Iron 3.7916597321
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 7.2212973940 20435036 12845720 11780464
MESH:D001749 Urinary Bladder Neoplasms decitabine 7.2217616700 19087683
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 7.2216712894 11723127 17306315 16452187
MESH:D014581 Urticaria Acetaminophen 2.5510982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 8.1416803524
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 8.1411813266
MESH:D014594 Uterine Neoplasms Benzene 8.1112562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.1114692618
MESH:D014604 Uveal Neoplasms decitabine 4.4417785578
MESH:D014605 Uveitis Dexamethasone 4.341336536
MESH:D014652 Vascular Diseases sodium arsenite 3.9617056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1212125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.1214671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.7715886252
MESH:D015430 Weight Gain Antipsychotic Agents 14.3920373477 20375926 18195716
MESH:D015430 Weight Gain Dietary Fats 14.3916723640
MESH:D015430 Weight Gain Risperidone 14.3916379507 20564506
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA34372
    • No data
    Releated disease ID Related disease Name
    PA445254Parkinson Disease
    PA447215Psychotic Disorders
    PA447288Essential hypertension
    Releated drug ID Related drug Name
    PA449061clozapine
    PA450688olanzapine
    PA451257risperidone
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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