AutismKB 2.0

Annotation Detail for RGS3


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Basic Information Top
Gene Symbol:RGS3 ( C2PA,FLJ20370,FLJ31516,FLJ90496,PDZ-RGS3,RGP3 )
Gene Full Name: regulator of G-protein signaling 3
Band: 9q32
Quick LinksEntrez ID:5998; OMIM: 602189; Uniprot ID:RGS3_HUMAN; ENSEMBL ID: ENSG00000138835; HGNC ID: 9999
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04360Axon guidance
No data
Pathway IDPathway Name
200173Ephrin B reverse signaling
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of RGS3 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of RGS3 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of RGS3 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RGS3 mRNAaffects expression 16483693
C015001 arsenite arsenite results in decreased expression of RGS3 mRNAdecreases expression 18929588
C015001 arsenite TRP53 protein affects the reaction [arsenite results in decreased expression of RGS3 mRNA]affects reaction|decreases expression 18929588
D017638 Asbestos, Crocidolite Asbestos, Crocidolite affects the expression of RGS3 mRNAaffects expression 17331233
D001554 Benzene Benzene results in increased expression of RGS3 mRNAincreases expression 17905399
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of RGS3 mRNAaffects expression 17484886
D004298 Dopamine RGS3 protein affects the reaction [Dopamine results in increased phosphorylation of and results in increased activity of MAPK1 protein]affects reaction|increases activity|increases phosphorylation 18977218
D004298 Dopamine RGS3 protein affects the reaction [Dopamine results in increased phosphorylation of and results in increased activity of MAPK3 protein]affects reaction|increases activity|increases phosphorylation 18977218
D004958 Estradiol [Progesterone co-treated with Estradiol] results in decreased expression of RGS3 mRNAaffects cotreatment|decreases expression 17404688
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of RGS3 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RGS3 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of RGS3 mRNAincreases expression 17351261
17108234
D005419 Flavonoids Flavonoids results in increased expression of RGS3 mRNAincreases expression 18035473
C475919 hydroxytamoxifen hydroxytamoxifen results in increased expression of RGS3 mRNAincreases expression 16849584
C030957 methylmercury II methylmercury II results in increased expression of RGS3 mRNAincreases expression 17905399
C023036 perfluorooctanoic acid perfluorooctanoic acid results in decreased expression of RGS3 mRNAdecreases expression 16221955
D010634 Phenobarbital Phenobarbital results in increased expression of RGS3 mRNAincreases expression 19363144
D010656 Phenylephrine RGS3 protein affects the reaction [[Timolol co-treated with Phenylephrine] results in increased phosphorylation of and results in increased activity of MAPK1 protein]affects cotreatment|affects reaction|increases activity|increases phosphorylation 18977218
D010656 Phenylephrine RGS3 protein affects the reaction [[Timolol co-treated with Phenylephrine] results in increased phosphorylation of and results in increased activity of MAPK3 protein]affects cotreatment|affects reaction|increases activity|increases phosphorylation 18977218
C025299 polyphenols polyphenols results in decreased expression of RGS3 mRNAdecreases expression 16293270
D011374 Progesterone [Progesterone co-treated with Estradiol] results in decreased expression of RGS3 mRNAaffects cotreatment|decreases expression 17404688
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RGS3 mRNAaffects cotreatment|increases expression 17942748
D013999 Timolol RGS3 protein affects the reaction [[Timolol co-treated with Phenylephrine] results in increased phosphorylation of and results in increased activity of MAPK1 protein]affects cotreatment|affects reaction|increases activity|increases phosphorylation 18977218
D013999 Timolol RGS3 protein affects the reaction [[Timolol co-treated with Phenylephrine] results in increased phosphorylation of and results in increased activity of MAPK3 protein]affects cotreatment|affects reaction|increases activity|increases phosphorylation 18977218
C081489 valsartan valsartan inhibits the reaction [AGT protein results in increased expression of RGS3 mRNA]decreases reaction|increases expression 19225232
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 7.866195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.8614514962 15322242 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.4318287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8117505938
MESH:D000230 Adenocarcinoma Estradiol 4.1111473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.1114692618
MESH:D018248 Adenoma, Liver Cell Phenobarbital 9.6417620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.6416835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8311748828
MESH:D000741 Anemia, Aplastic Benzene 4.2711369114 14761424 17661222
MESH:D000799 Angioedema Acetaminophen 3.7110982225
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 4.0017460149
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.3311256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5815885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 2.9212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6815746008
MESH:D001855 Bone Marrow Diseases Benzene 5.1016183116
MESH:D001919 Bradycardia Phenylephrine 4.4115306635
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.2117868700
MESH:D001930 Brain Injuries Progesterone 4.1315380490 15845082 15665606
MESH:D001943 Breast Neoplasms Benzene 1.9511921183 17162533
MESH:D001943 Breast Neoplasms Estradiol 1.9512948864 17261762 18497071 16675129 17018787 14630087 19861407 17289903
MESH:D001943 Breast Neoplasms Progesterone 1.9516175315 17614352 15562024
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9520435547
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3316111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.6516011737 15721981 18705752 16227642 16050911 10355542 16192424 3786805 16124888 15673190 16097048 15700767
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6916835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 11.1116705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 11.1116705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.113084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 11.1118788625
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.1116924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 11.116705139 1701930 17173139 20007298 20935162
MESH:D006332 Cardiomegaly Phenylephrine 11.1715728586 16170337 17124262 11754973 11179087 17287366
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 11.1718850075 18670907 16120746
MESH:D006332 Cardiomegaly valsartan 11.1719597038
MESH:D009202 Cardiomyopathies valsartan 4.3516247790
MESH:D002318 Cardiovascular Diseases valsartan 4.2111230374
MESH:D002386 Cataract Acetaminophen 2.5110977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 6.366135515
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.3618566989
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.124080065
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0516835633
MESH:D002779 Cholestasis Ethinyl Estradiol 2.7817110522 17681005 15861022 16105132 17333356 16919318 11677210
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0516354765 8697196 12621046 15668235 15340226
MESH:D003110 Colonic Neoplasms arsenite 4.0415037631
MESH:D003110 Colonic Neoplasms polyphenols 4.0416293270
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9517141729 14669216
MESH:D003324 Coronary Artery Disease valsartan 3.8517719468
MESH:D003384 Coxsackievirus Infections valsartan 5.7120392896
MESH:D019465 Craniofacial Abnormalities Benzene 2.6415643154
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.6415322242 20055451 10048152
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.4618551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.4618551238
MESH:D003872 Dermatitis Benzene 4.6415902427
MESH:D003921 Diabetes Mellitus, Experimental valsartan 4.4911508273
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6417107852
MESH:D003928 Diabetic Nephropathies Estradiol 8.9519279558
MESH:D003928 Diabetic Nephropathies valsartan 8.9511427623 18630688
MESH:D003929 Diabetic Neuropathies Progesterone 4.3617187935
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 14.7521346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 14.7521346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 14.7511743745 16177239 11421492 19739265 19164858 16081117 17562736 14986274 19923254 10915739 19420014 19085960 12594235 10663392 17522070 18071297 15968718 14550746 10774834 17906064 11739529 19416960 2444490 11287661 19370779 12153990 16393943 11834606 15619225 11529661 12392966 16227642 16485898 12540782 16109766 14725611 16781746 18713872 11461765 12958197 12705907
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 14.7511566570 21278145 6884620 3732212 2869522 7120509 10092053 4309450 7179309 16227642 15027814 17522070 19336974 7440962 10915739 15998439 3786805 16177239 15968718 19085960 6623471 9327722
MESH:D056486 Drug-Induced Liver Injury polyphenols 14.7519370779
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 14.7520420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6611462148
MESH:D004421 Dystonia Phenobarbital 3.881851702
MESH:D004487 Edema perfluorooctanoic acid 6.5517259670 12083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.5511000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7718230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.6112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 8.6117692515
MESH:D016889 Endometrial Neoplasms Estradiol 2.9019148513 18566989 11473722
MESH:D004715 Endometriosis Progesterone 8.5416134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.549294722 10568697
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.983659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.743922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.8220417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.436401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.127750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.893659116
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9111564622
MESH:D005234 Fatty Liver arsenite 12.4818296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 12.4817595544 19224547 12795759 12631006 15959796 61145 16239168 16045604
MESH:D005234 Fatty Liver Ethinyl Estradiol 12.4815345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3311858732
MESH:D005355 Fibrosis arsenite 20.1718296743
MESH:D005355 Fibrosis Carbon Tetrachloride 20.1718705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 20.1720067830
MESH:D005355 Fibrosis valsartan 20.1716893502
MESH:D005756 Gastritis Acetaminophen 3.5516983495
MESH:D015432 Glomerulonephritis, Membranoproliferative valsartan 5.4116928621
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4710696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2610048152 11294989
MESH:D006333 Heart Failure valsartan 4.1719027736
MESH:D006402 Hematologic Diseases Benzene 4.5316183116
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2111000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.4719110552 19900420
MESH:D006529 Hepatomegaly perfluorooctanoic acid 13.783609246
MESH:D006529 Hepatomegaly Phenobarbital 13.7816109766
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 13.7812621046 15340226 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.9015709030
MESH:D019584 Hot Flashes Estradiol 3.6217088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9216354765 8697196 16959395 18606429 15340226
MESH:D006930 Hyperalgesia Acetaminophen 7.5116870215
MESH:D006930 Hyperalgesia perfluorooctanoic acid 7.5112083418
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.4016899240
MESH:D006973 Hypertension Benzene 12.0817940673
MESH:D006973 Hypertension Phenylephrine 12.088949925 12717712
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 12.0818670907 18850075
MESH:D006973 Hypertension valsartan 12.0816475468 18390891 18344623 11427623 12692753 20102058 12850387 10903974
MESH:D006974 Hypertension, Malignant valsartan 6.2811560862
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9615338365
MESH:D006984 Hypertrophy Phenylephrine 4.4318502941 12791704
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6816945680 16569931
MESH:D007022 Hypotension Dopamine 4.896740701
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.2715869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3412013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4017937319
MESH:D007249 Inflammation Flavonoids 15.1717296493
MESH:D007249 Inflammation perfluorooctanoic acid 15.1712083418
MESH:D007249 Inflammation polyphenols 15.1716366677
MESH:D007249 Inflammation Progesterone 15.1715869954
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 15.1712200463 12878042
MESH:D007333 Insulin Resistance Estradiol 2.8816393666 16627594
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2116580747
MESH:D007674 Kidney Diseases Acetaminophen 9.7615629191 12587719
MESH:D007674 Kidney Diseases Estradiol 9.7615618244
MESH:D007674 Kidney Diseases valsartan 9.7616893502 12164870 10903974
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 11.7716705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 11.7716705839
MESH:D007680 Kidney Neoplasms Estradiol 11.7715610895
MESH:D007938 Leukemia Benzene 3.3314694614 17119257 18335105 15935818
MESH:D007951 Leukemia, Myeloid Benzene 4.2017506065
MESH:D015470 Leukemia, Myeloid, Acute Benzene 2.6819478238
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 5.108812269
MESH:D008103 Liver Cirrhosis arsenite 10.6918296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.6911903743 16943688 17334410 16239168 17174718 16221502 21278145 11408273 17157831
MESH:D008103 Liver Cirrhosis Phenobarbital 10.6921047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.8715052691 17761835 15673190 10355542 12649538 17721639 16116963 15876570 17823541 16027843 17698563 18263696 17565644 14716833 15925388 14724832 12632514 17766677 12898905 17708605 12666154 15959796 18317297 18429990 14716496 15818738 15370692 18156304 17557913 17525996 14748882 18187930 15650968 12667390 15893842 12958196 17481882 15123356 18472094 16192424 12389079 12445421 14512876 12546737 18210741 18251166 16015684 18420326 17805973 18418968 12445418 18481824 16638106 12609069 17869086 18395095 18412020 17714472 18006644 16033810 18472332 18705752 14620537 13678700 18054572 15057751 15931870 12586293 15338365 18376398 16136751 18205269 18395914 15362042 18277467 17976157 16248980 17944888 17922224 18166357 11481614 17640975 15996030 16011737 16097048 15730626 20821823 12632512 12741479 17631135 17900296 18339082 18279442
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 4.8714659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.8712878042
MESH:D008106 Liver Cirrhosis, Experimental valsartan 4.8715619341 16872305 15504291
MESH:D008107 Liver Diseases Acetaminophen 9.1219014921 11587558 16610002 12587719 19784758 16611625 19460945 12969438
MESH:D008107 Liver Diseases Carbon Tetrachloride 9.1215830285 16246199 15720792 16964402 17285989
MESH:D008107 Liver Diseases Phenobarbital 9.1219363144
MESH:D008107 Liver Diseases polyphenols 9.1216698588
MESH:D017093 Liver Failure Carbon Tetrachloride 4.0315123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.0217185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.0216899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 13.727678174
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 13.7219294768
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 13.7214757943 18709148
MESH:D008113 Liver Neoplasms Phenobarbital 13.7219812893 19073162 19482888 8742319 15975961 21047994
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 13.7216984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 17.792876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental Benzene 17.7912562636
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 17.7915583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 17.796150874 1399818 17172636 2563599 18308698
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 17.7912151625
MESH:D017563 Lung Diseases, Interstitial Benzene 4.6814698565
MESH:D055370 Lung Injury Asbestos, Crocidolite 3.8917365036
MESH:D008175 Lung Neoplasms arsenite 3.4616809336
MESH:D008175 Lung Neoplasms Benzene 3.4612562636
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.4619555203 11884234
MESH:D008223 Lymphoma Benzene 3.6417119257 17584886
MESH:D015674 Mammary Neoplasms, Animal Benzene 4.3112562636
MESH:D008325 Mammary Neoplasms, Experimental Benzene 9.5811921183
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 9.5811807958 11408345 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 9.5817203775 11408345
MESH:D020149 Manganese Poisoning Estradiol 4.3519453300
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4419513568
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.1316166281 18303189 16966607
MESH:D009101 Multiple Myeloma Benzene 3.5717119195
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.1816810080
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.3417484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 9.9118551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 9.9118551238 7678174
MESH:D009389 Neovascularization, Pathologic arsenite 9.7115738583
MESH:D009389 Neovascularization, Pathologic Estradiol 9.7117289903
MESH:D009421 Nervous System Malformations Estradiol 9.0411399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.0414600291
MESH:D009436 Neural Tube Defects Benzene 3.5915643154
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.7618514411
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.829802331
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 14.4912819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 14.4916049721
MESH:D009784 Occupational Diseases Benzene 14.4917479406 15727169 15612468 17119257 17178637 15576619 15913788 15935809 16737584
MESH:D010018 Osteomalacia Phenobarbital 4.2317016548
MESH:D010051 Ovarian Neoplasms Benzene 7.7312562636
MESH:D010051 Ovarian Neoplasms Estradiol 7.7319401270
MESH:D010051 Ovarian Neoplasms Progesterone 7.7316525653 17393432
MESH:D010146 Pain Acetaminophen 2.2916870215
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.4516965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5611578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1212520081
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.7610923243
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4318163543
MESH:D011230 Precancerous Conditions Phenobarbital 3.512563599
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 9.2317132714
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.2311896295 11222880 11118676 11399792
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.7620887781
MESH:D011471 Prostatic Neoplasms Estradiol 3.1216740699
MESH:D011507 Proteinuria valsartan 4.7317664856 12164870 18344623
MESH:D011537 Pruritus Ethinyl Estradiol 3.1815861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 4.3712752131
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 6.0715814490 17365031 17975199 17322281
MESH:D011658 Pulmonary Fibrosis valsartan 6.0717241526
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7118990726
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.8118045962
MESH:D012640 Seizures 2,4-dinitrotoluene 9.2918551238
MESH:D012640 Seizures 2,6-dinitrotoluene 9.2918551238
MESH:D012640 Seizures Phenobarbital 9.2911442880 4039156 3137016 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.696407741
MESH:D012852 Sinusitis Phenylephrine 4.577327846
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 1.9816192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.8116709447
MESH:D013119 Spinal Cord Injuries Progesterone 4.1516503802 15862959
MESH:D013274 Stomach Neoplasms Benzene 2.4112562636
MESH:D013705 Temporomandibular Joint Disorders polyphenols 5.1217997062
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0415669648
MESH:D013953 Thymus Neoplasms Benzene 4.8210850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7712697716
MESH:D013964 Thyroid Neoplasms Phenobarbital 2.951399818
MESH:D013978 Tibial Fractures Estradiol 4.5619048282
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 4.8416049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 4.8416049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.5510091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.5510091137
MESH:D014581 Urticaria Acetaminophen 2.8510982225
MESH:D014594 Uterine Neoplasms Benzene 9.1512562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.1514692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4215869587 14671159
MESH:D020257 Ventricular Remodeling valsartan 5.5719027736
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1215886252
Pathway ID Pathway Name
KEGG:04360 Axon guidance
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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