Annotation Detail for FAM3A
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D006830 |
Hydralazine |
[Hydralazine co-treated with Valproic Acid] results in increased expression of FAM3A mRNA | affects cotreatment|increases expression | 17183730
|
| D012643 |
Selenium |
[Selenium co-treated with Vitamin E] results in decreased expression of FAM3A mRNA | affects cotreatment|decreases expression | 19244175
|
| D012643 |
Selenium |
Selenium results in increased expression of FAM3A mRNA | increases expression | 19244175
|
| D014635 |
Valproic Acid |
[Hydralazine co-treated with Valproic Acid] results in increased expression of FAM3A mRNA | affects cotreatment|increases expression | 17183730
|
| D014810 |
Vitamin E |
[Selenium co-treated with Vitamin E] results in decreased expression of FAM3A mRNA | affects cotreatment|decreases expression | 19244175
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Valproic Acid |
4.11 | 8875741 |
| MESH:D000015 |
Abnormalities, Multiple |
|
Valproic Acid |
4.35 | 19490988 |
| MESH:D000550 |
Amblyopia |
|
Valproic Acid |
5.96 | 17688650 |
| MESH:D001008 |
Anxiety Disorders |
|
Valproic Acid |
3.90 | 17497229 |
| MESH:D001321 |
Autistic Disorder |
|
Valproic Acid |
1.98 | 16609825 20603192 18775368 17507914 17688650 18316065 17157402 18558336 19232924 18940202 19460635 15238991 18177632 18985861 18396377 |
| MESH:D001714 |
Bipolar Disorder |
|
Valproic Acid |
3.24 | 17594078 20046352 |
| MESH:D001848 |
Bone Diseases, Developmental |
|
Valproic Acid |
3.63 | 8888407 |
| MESH:D002252 |
Carbon Tetrachloride Poisoning |
|
Vitamin E |
4.49 | 16050911 |
| MESH:D002659 |
Child Development Disorders, Pervasive |
|
Valproic Acid |
2.82 | 20734317 |
| MESH:D003092 |
Colitis |
|
Selenium |
4.34 | 17936198 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Valproic Acid |
2.80 | 8888407 17688650 16575769 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Vitamin E |
2.80 | 19769572 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Selenium |
4.31 | 15131321 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Valproic Acid |
4.31 | 1733752 19641884 |
| MESH:D004421 |
Dystonia |
|
Valproic Acid |
4.51 | 1851702 |
| MESH:C538011 |
Eales disease |
|
Vitamin E |
5.43 | 9068938 |
| MESH:D004831 |
Epilepsies, Myoclonic |
|
Valproic Acid |
4.71 | 17275665 3659116 |
| MESH:D004828 |
Epilepsies, Partial |
|
Valproic Acid |
4.64 | 3922381 16628512 |
| MESH:D004827 |
Epilepsy |
|
Valproic Acid |
3.11 | 20417680 18234410 |
| MESH:D004832 |
Epilepsy, Absence |
|
Valproic Acid |
3.96 | 6426943 7562514 6254150 |
| MESH:D017029 |
Epilepsy, Complex Partial |
|
Valproic Acid |
4.86 | 7750514 |
| MESH:D004830 |
Epilepsy, Tonic-Clonic |
|
Valproic Acid |
4.69 | 3659116 |
| MESH:D005234 |
Fatty Liver |
|
Valproic Acid |
3.72 | 19224547 14986274 |
| MESH:D005315 |
Fetal Diseases |
|
Valproic Acid |
5.61 | 16575769 |
| MESH:D005317 |
Fetal Growth Retardation |
|
Valproic Acid |
4.64 | 8888407 18558336 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Vitamin E |
3.17 | 16080930 |
| MESH:D006333 |
Heart Failure |
|
Selenium |
3.29 | 17162251 |
| MESH:D006548 |
Hernia, Diaphragmatic |
|
Vitamin E |
2.81 | 16490937 16863852 |
| MESH:D019584 |
Hot Flashes |
|
Vitamin E |
4.69 | 14716179 |
| MESH:D006849 |
Hydrocephalus |
|
Valproic Acid |
5.50 | 17688650 |
| MESH:D046110 |
Hypertension, Pregnancy-Induced |
|
Hydralazine |
5.19 | 16612254 |
| MESH:D007251 |
Influenza, Human |
|
Selenium |
13.50 | 16624496 |
| MESH:D007251 |
Influenza, Human |
|
Vitamin E |
13.50 | 16624496 |
| MESH:D007674 |
Kidney Diseases |
|
Vitamin E |
3.00 | 12488133 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Selenium |
4.31 | 16518626 |
| MESH:D015470 |
Leukemia, Myeloid, Acute |
|
Valproic Acid |
2.20 | 16294345 17596541 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Vitamin E |
1.91 | 16169303 |
| MESH:D008171 |
Lung Diseases |
|
Vitamin E |
3.43 | 16863852 |
| MESH:D017563 |
Lung Diseases, Interstitial |
|
Valproic Acid |
4.98 | 17228818 |
| MESH:D008175 |
Lung Neoplasms |
|
Vitamin E |
1.90 | 11062179 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Selenium |
2.99 | 15318939 |
| MESH:D008654 |
Mesothelioma |
|
Selenium |
2.92 | 15107826 |
| MESH:D008881 |
Migraine Disorders |
|
Valproic Acid |
3.47 | 18765137 18803445 |
| MESH:D009139 |
Musculoskeletal Abnormalities |
|
Valproic Acid |
4.45 | 8888407 |
| MESH:D009190 |
Myelodysplastic Syndromes |
|
Valproic Acid |
3.35 | 17596541 |
| MESH:D009436 |
Neural Tube Defects |
|
Valproic Acid |
3.37 | 16359493 8888407 |
| MESH:D010954 |
Plasmacytoma |
|
Selenium |
5.61 | 15087411 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
Valproic Acid |
4.46 | 20603192 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Vitamin E |
3.24 | 15084515 |
| MESH:D019310 |
Pseudolymphoma |
|
Valproic Acid |
5.26 | 11422049 12752131 |
| MESH:D012208 |
Rhabdomyosarcoma |
|
Valproic Acid |
4.64 | 19155313 |
| MESH:D012559 |
Schizophrenia |
|
Valproic Acid |
2.10 | 19110320 15737665 |
| MESH:D012640 |
Seizures |
|
Valproic Acid |
2.99 | 16876388 14763951 17978042 1511512 11738929 3137016 15475178 11044598 |
| MESH:D012871 |
Skin Diseases |
|
Vitamin E |
2.52 | 18709164 |
| MESH:D016135 |
Spinal Dysraphism |
|
Valproic Acid |
4.09 | 19490988 |
| MESH:D013226 |
Status Epilepticus |
|
Valproic Acid |
5.26 | 12833885 |
| MESH:D020521 |
Stroke |
|
Vitamin E |
3.84 | 16517955 |
| MESH:D014178 |
Translocation, Genetic |
|
Valproic Acid |
5.96 | 17262798 |
| MESH:D020194 |
Unverricht-Lundborg Syndrome |
|
Valproic Acid |
5.15 | 3119515 |
| MESH:D014564 |
Urogenital Abnormalities |
|
Valproic Acid |
5.20 | 8888407 |
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