AutismKB 2.0

Annotation Detail for APOBEC3G


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:APOBEC3G ( ARCD,ARP-9,ARP9,CEM-15,CEM15,FLJ12740,bK150C2.7,dJ494G10.1 )
Gene Full Name: apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
Band: 22q13.1
Quick LinksEntrez ID:60489; OMIM: 607113; Uniprot ID:ABC3G_HUMAN; ENSEMBL ID: ENSG00000128394; HGNC ID: 17357
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1712Yersinia infection
1772Peptic ulcer
1809HIV infection
1865Hyperopia
1871Hepatitis
2093Viremia
2147Neurotic disorder
Desease Name
HIV
INFECTION
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of APOBEC3G proteinaffects expression 20106945
D001374 Azacitidine Azacitidine results in increased expression of APOBEC3G mRNAincreases expression 19194470
D004958 Estradiol Estradiol results in increased expression of APOBEC3G mRNAincreases expression 19139166
D007529 Isoflavones Isoflavones affects the expression of APOBEC3G mRNAaffects expression 16365062
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of APOBEC3G mRNAincreases expression 20106945
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.3815322242 14514962 11752688
MESH:D000230 Adenocarcinoma Estradiol 2.1611473722
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.9216835633
MESH:D000505 Alopecia Isoflavones 5.0117569567
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.2911748828
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.4212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.4015340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.9715746008
MESH:D001943 Breast Neoplasms Estradiol 1.9012948864 17261762 16675129 19861407 18497071 17289903 14630087 17018787
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9020435547
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 5.0016111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 3.0916835633
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 3.1612619106 12907637 21507988
MESH:D006528 Carcinoma, Hepatocellular Estradiol 3.1616924424
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.5418670907 18850075 16120746
MESH:D002318 Cardiovascular Diseases Isoflavones 4.3817689850
MESH:D002471 Cell Transformation, Neoplastic Estradiol 3.0018566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.4916835633
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.2212621046 8697196 15668235 16354765 15340226
MESH:D015179 Colorectal Neoplasms Azacitidine 3.2619934284
MESH:D015179 Colorectal Neoplasms Isoflavones 3.2617116718
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.3817141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2720055451 15322242 10048152
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7317107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.7419279558
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 1.6120420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 3.0211462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.7411000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.5116714409 15322242 18230668
MESH:D016889 Endometrial Neoplasms Estradiol 3.2019148513 11473722 18566989
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.3710568697 9294722
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.2711564622
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.9411858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.4320067830
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.2110696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.4910048152 11294989
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.7111000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.3712621046 15340226 16120746
MESH:D006558 Herpes Genitalis Estradiol 5.6415709030
MESH:D019584 Hot Flashes Estradiol 12.5517088409
MESH:D019584 Hot Flashes Isoflavones 12.5514716179 17290160
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.6618606429 8697196 15340226 16354765 16959395
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 2.0118850075 18670907
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 2.0112878042 12200463
MESH:D007333 Insulin Resistance Estradiol 3.1816627594 16393666
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.7116580747
MESH:D007674 Kidney Diseases Estradiol 2.7615618244
MESH:D007680 Kidney Neoplasms Estradiol 3.2815610895
MESH:D007938 Leukemia Azacitidine 3.8419148494
MESH:D007951 Leukemia, Myeloid Azacitidine 4.9919077051
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 3.0417596541 18720364
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 5.6019299654
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 2.3414659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.3412878042
MESH:D008113 Liver Neoplasms Aflatoxin B1 4.8115890375 2125692 9163691 18177683
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.8116984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 6.498603461
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 6.4912151625
MESH:D008175 Lung Neoplasms Aflatoxin B1 3.6914755239
MESH:D008175 Lung Neoplasms Azacitidine 3.6921224363
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.6919555203 11884234
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.7717203775 11807958 16891317 11408345
MESH:D020149 Manganese Poisoning Estradiol 5.0919453300
MESH:D009006 Monosomy Azacitidine 6.6919299654
MESH:D009101 Multiple Myeloma Azacitidine 4.2118443271 19549372
MESH:D009190 Myelodysplastic Syndromes Azacitidine 4.1817596541 18720364 17611569 19805378
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.3112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.5516810080
MESH:D009389 Neovascularization, Pathologic Estradiol 4.2717289903
MESH:D009421 Nervous System Malformations Estradiol 10.9711399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 10.9714600291
MESH:D010024 Osteoporosis Isoflavones 4.3016562857
MESH:D010051 Ovarian Neoplasms Estradiol 2.3019401270
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.8612520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 4.0018163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.7311896295 11399792 11118676 11222880
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.2620887781
MESH:D011471 Prostatic Neoplasms Azacitidine 2.7618324645
MESH:D011471 Prostatic Neoplasms Estradiol 2.7616740699
MESH:D011471 Prostatic Neoplasms Isoflavones 2.7617571952 17219775 16365062 17374662
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.2818990726
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.1816192470
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.5112697716
MESH:D013978 Tibial Fractures Estradiol 5.3019048282
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.2112125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.8615886252
Pathway ID Pathway Name
REACT:6185 HIV Infection
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA24897
    • Releated gene ID Related gene Name
    PA24897APOBEC3G
    No data
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved