Annotation Detail for AASDHPPT
Basic Information
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| Gene Symbol: | AASDHPPT ( AASD-PPT,DKFZp566E2346,LYS2,LYS5 ) |
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| Gene Full Name: | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase |
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| Band: | 11q22.3 |
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| Quick Links | Entrez ID:60496; OMIM: 607756; Uniprot ID:ADPPT_HUMAN; ENSEMBL ID: ENSG00000149313; HGNC ID: 14235 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| PWY-6012 | acyl carrier protein metabolism |
| Pathway ID | Pathway Name |
|---|
| Metabolism of vitamins and cofactors |
| Pathway ID | Pathway Name |
|---|
| 500597 | Vitamin B5 (pantothenate) metabolism |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of AASDHPPT mRNA | affects expression | 17562736
|
| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of AASDHPPT mRNA | decreases expression | 19150397
|
| C006253 |
pirinixic acid |
pirinixic acid results in increased expression of AASDHPPT mRNA | increases expression | 18301758
|
| D014501 |
Uranium |
Uranium affects the expression of AASDHPPT mRNA | affects expression | 15672453
|
| C005460 |
uranyl acetate |
uranyl acetate affects the expression of AASDHPPT mRNA | affects expression | 15672453
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.52 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.02 | 16434500 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.45 | 10982225 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.52 | 19483382 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
1.40 | 3084413 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.77 | 10977129 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.96 | 20889678 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.08 | 19176532 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.56 | 18249437 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
1.66 | 12705907 11739529 11421492 11743745 17522070 11529661 16781746 11287661 14725611 12153990 11461765 15619225 18071297 10915739 15968718 19923254 19416960 17906064 12958197 19739265 11834606 2444490 19085960 10663392 16081117 18713872 19420014 12540782 16393943 14550746 19164858 12392966 12594235 14986274 16177239 17562736 16109766 19370779 16485898 16227642 10774834 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.71 | 19426721 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.85 | 12083418 |
| MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.14 | 20426865 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.14 | 20131406 19236843 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.29 | 16983495 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.73 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.48 | 18467677 19176532 16221962 19772884 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
2.99 | 16870215 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.53 | 20558911 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.85 | 16306350 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.38 | 15629191 12587719 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.69 | 16611625 19460945 12969438 19014921 16610002 11587558 12587719 19784758 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.58 | 16871587 17185352 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.92 | 20007298 15890375 16377806 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.05 | 19513568 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
3.99 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.26 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.22 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.09 | 17405874 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.18 | 18514411 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.88 | 20558911 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.69 | 16870215 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.53 | 19058328 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.38 | 10982225 |
| Pathway ID |
Pathway Name |
|---|
| REACT:11193 |
Metabolism of vitamins and cofactors |
| KEGG:00770 |
Pantothenate and CoA biosynthesis |
Related Diseases/Disorders