AutismKB 2.0

Annotation Detail for TNFRSF17


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Basic Information Top
Gene Symbol:TNFRSF17 ( BCM,BCMA,CD269 )
Gene Full Name: tumor necrosis factor receptor superfamily, member 17
Band: 16p13.13
Quick LinksEntrez ID:608; OMIM: 109545; Uniprot ID:TNR17_HUMAN; ENSEMBL ID: ENSG00000048462; HGNC ID: 11913
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04672Intestinal immune network for IgA production
hsa04060Cytokine-cytokine receptor interaction
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1707Multiple myeloma
1781Rheumatoid arthritis
Desease Name
CARDIOVASCULAR
QT interval
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C061133 Am 80 Am 80 results in increased expression of TNFRSF17 mRNAincreases expression 17229644
C006632 arsenic trioxide arsenic trioxide results in decreased expression of TNFRSF17 mRNAdecreases expression 17530438
D010615 Phenacetin Phenacetin results in decreased expression of TNFRSF17 mRNAdecreases expression 17698508
C030299 phenylhydrazine phenylhydrazine results in decreased expression of TNFRSF17 mRNAdecreases expression 17698508
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma arsenic trioxide 2.3611798837 19825857
MESH:D000740 Anemia Phenacetin 11.232444515
MESH:D000740 Anemia phenylhydrazine 11.232444515
MESH:D000743 Anemia, Hemolytic Phenacetin 12.5117698508 1949026 17082564
MESH:D000743 Anemia, Hemolytic phenylhydrazine 12.5117082564 17698508 17084956
MESH:D001172 Arthritis, Rheumatoid Am 80 3.8216819260
MESH:D050197 Atherosclerosis Am 80 4.5516484594
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 4.1016206674
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.7911589617
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 1.9815073043 14691202 15553829 16217749 11135700
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.6019014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.5112490120
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.6912609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8910525206
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.5615213294
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Am 80 5.5916819260
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.3812903497
MESH:D005234 Fatty Liver arsenic trioxide 3.7115073043
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.7716904648
MESH:D007938 Leukemia arsenic trioxide 3.0015070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.2212560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.9416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.7214633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.1919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1919850784 17050201 16467208 16968895 20471514
MESH:D015473 Leukemia, Promyelocytic, Acute Am 80 9.0016819260 16531727
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 9.0016331271 16823087 11468182 19225113 15336539 16966277 12712474 12679006 9834237 16891316 19035177 16330433 17107899 17649720 12018890 15213294 16112521 17217047 17712046 11161223 19642359 15622746 15748426 19075265 17869043
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.8616882451
MESH:D008113 Liver Neoplasms arsenic trioxide 2.4614682389
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 2.9620377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.6615213294
MESH:D008175 Lung Neoplasms arsenic trioxide 1.8719825857 11798837
MESH:D008708 Methemoglobinemia Phenacetin 5.414834387 16296465 1949026 3537620
MESH:D009101 Multiple Myeloma Am 80 8.7517229644
MESH:D009101 Multiple Myeloma arsenic trioxide 8.7514977855 11468182 19549372 19417148 15949261
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.4018349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3416105982 16882451
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.4716624393
MESH:D009436 Neural Tube Defects arsenic trioxide 3.3610525206
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.5016624393 12452020 19769630
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6315580305
MESH:D010235 Paraganglioma arsenic trioxide 4.6319927285
MESH:D011471 Prostatic Neoplasms Am 80 3.7316289102
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.7319131511
MESH:D011565 Psoriasis Am 80 4.1916819260
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.4716646077
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D013436 Sulfhemoglobinemia Phenacetin 7.28978859
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.3919014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.5915213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 6.0720435036 11780464 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms Phenacetin 6.0711144890
Pathway ID Pathway Name
KEGG:04060 Cytokine-cytokine receptor interaction
KEGG:04672 Intestinal immune network for IgA production
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA36606
    • No data
    Releated disease ID Related disease Name
    PA446969Venous Thrombosis
    Releated drug ID Related drug Name
    PA451644thalidomide
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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