AutismKB 2.0

Annotation Detail for RORA


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RORA ( DKFZp686M2414,MGC119326,MGC119329,NR1F1,ROR1,ROR2,ROR3,RZR-ALPHA,RZRA )
Gene Full Name: RAR-related orphan receptor A
Band: 15q22.2
Quick LinksEntrez ID:6095; OMIM: 600825; Uniprot ID:RORA_HUMAN; ENSEMBL ID: ENSG00000069667; HGNC ID: 10258
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04710Circadian rhythm - mammal
Pathway IDPathway Name
Gene Expression
Pathway IDPathway Name
200172HIF-1-alpha transcription factor network
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1784Choriocarcinoma
1856Obesity
1918Atherosclerosis
Desease Name
CHEMDEPENDENCY
PHARMACOGENOMIC
response to citalopram treatment
smoking cessation
Desease Name
Depression--quantitative trait
Asthma
Response to citalopram treatment
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of RORA proteinaffects expression 20106945
D013196 Dihydrotestosterone Dihydrotestosterone promotes the reaction [AR protein binds to RORA promoter]affects binding|increases reaction 21359227
D013196 Dihydrotestosterone Dihydrotestosterone results in decreased expression of RORA mRNAdecreases expression 21359227
C006632 arsenic trioxide arsenic trioxide results in increased expression of RORA mRNAincreases expression 15073043
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of RORA mRNAdecreases expression 20106945
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of RORA mRNAincreases expression 20064835
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of RORA mRNAincreases expression 15336504
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of RORA mRNAaffects expression 17484886
C014347 decitabine decitabine results in increased expression of RORA mRNAincreases expression 16367923
D003907 Dexamethasone Dexamethasone results in increased expression of RORA mRNAincreases expression 19022236
D004041 Dietary Fats Dietary Fats results in decreased expression of RORA mRNAdecreases expression 18042831
D004958 Estradiol Estradiol promotes the reaction [ESR1 protein binds to RORA promoter]affects binding|increases reaction 21359227
D004958 Estradiol Estradiol results in increased expression of RORA mRNAincreases expression 21359227
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of RORA mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of RORA mRNAdecreases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of RORA mRNAdecreases expression 17351261
D008550 Melatonin Melatonin binds to RORA proteinaffects binding 16030176
C041786 palm oil palm oil results in decreased expression of RORA mRNAdecreases expression 18042831
D010634 Phenobarbital Phenobarbital results in increased expression of RORA mRNAincreases expression 19270015
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of RORA mRNAaffects binding|decreases expression|increases activity 19710929
D013629 Tamoxifen Tamoxifen affects the expression of RORA mRNAaffects expression 17555576
C004648 testosterone enanthate testosterone enanthate results in increased expression of RORA mRNAincreases expression 17440010
C025643 vinclozolin vinclozolin affects the expression of RORA mRNAaffects expression 19015723
D014810 Vitamin E Vitamin E results in decreased expression of RORA mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.4914745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 3.386195326
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8917505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.0518653653
MESH:D000230 Adenocarcinoma arsenic trioxide 10.0211798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 10.0220127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 10.0211473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 10.0214692618
MESH:D000236 Adenoma Benzo(a)pyrene 7.066695378
MESH:D000236 Adenoma Melatonin 7.0617195641
MESH:D018248 Adenoma, Liver Cell Phenobarbital 9.9217620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.9216434500
MESH:D001008 Anxiety Disorders vinclozolin 3.5819015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.0119183758
MESH:D001161 Arteriosclerosis Dietary Fats 9.7015238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.7011256880
MESH:D001169 Arthritis, Experimental Dexamethasone 7.2417659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.2415885639
MESH:D001321 Autistic Disorder marker/mechanism 21359227 20375269
MESH:D001321 Autistic Disorder Melatonin 3.4116919138 16897403
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 8.7916206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.7919483382
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.3117474063 20146248
MESH:D001943 Breast Neoplasms decitabine 2.3118320071 19208741
MESH:D001943 Breast Neoplasms Dietary Fats 2.3120435547
MESH:D001943 Breast Neoplasms Estradiol 2.3117289903 14630087 17018787 17261762 18497071 16675129 19861407 12948864
MESH:D001943 Breast Neoplasms Tamoxifen 2.3117440819 18855134 17261762 18997820 20390343 19066611 18984771 16818667 21138602 19142967 19011961 19189210 17049068 18821012 19487384 20065188 20005174 20135344 19200415 16202921 21152245 11161223 19410462 19244106 19103187 19084267 19289846 19059307 19288272 18815881 20859285 17893378 16873071 16273361 15668708 19155303 18425577 15565566 18629630 19221464 18351453 19115204 19189212 20544844 17242785
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.2711589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.4016111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 16.6216124888 15700767 16097048 18705752 3786805 15721981 16192424 16011737 10355542 16227642 15673190 16050911
MESH:D002252 Carbon Tetrachloride Poisoning Melatonin 16.6215700767
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 16.6216050911
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.4419066611
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 11.2621507988 12619106 12907637
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 11.2616217749 15073043 14691202 11135700 15553829
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 11.2618788625
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.2616924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 11.2617173139 1701930 20007298 20935162 6705139
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.2616924424
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.8219014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.0612490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.6120419170
MESH:D002294 Carcinoma, Squamous Cell decitabine 4.6119215824
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.5517572228
MESH:D002471 Cell Transformation, Neoplastic Estradiol 2.7318566989
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.194080065
MESH:D002779 Cholestasis Ethinyl Estradiol 7.5817681005 16919318 16105132 15861022 17110522 11677210 17333356
MESH:D002779 Cholestasis pirinixic acid 7.5819176532
MESH:D003110 Colonic Neoplasms decitabine 3.9217616700
MESH:D003110 Colonic Neoplasms Dexamethasone 3.9215824018
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.5720501625
MESH:D015179 Colorectal Neoplasms decitabine 2.5718981723
MESH:D023903 Coronary Restenosis arsenic trioxide 4.1212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.8710525206
MESH:D019465 Craniofacial Abnormalities Dexamethasone 3.8717728286
MESH:D019465 Craniofacial Abnormalities Vitamin E 3.8719769572
MESH:D003456 Cryptorchidism vinclozolin 4.2814966744
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.0315213294
MESH:D003711 Demyelinating Diseases Tamoxifen 4.3019031437
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 3.3412438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3918249437
MESH:D003928 Diabetic Nephropathies Estradiol 8.6519279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.6519279558
MESH:D003967 Diarrhea Dexamethasone 3.637237001
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 2.029327722 3786805 19085960 11566570 10092053 6623471 7179309 4309450 15027814 17522070 21278145 15968718 16177239 15998439 2869522 19336974 16227642 3732212 7440962 7120509 6884620 10915739
MESH:D050171 Dyslipidemias Dietary Fats 3.4018367378
MESH:D004421 Dystonia Phenobarbital 3.941851702
MESH:C538011 Eales disease Vitamin E 4.659068938
MESH:D004485 Eczema Dexamethasone 4.4012438553
MESH:D004487 Edema Dexamethasone 6.7119703484
MESH:D004487 Edema pirinixic acid 6.7112083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.7312538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.7319031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.0619294695
MESH:D016889 Endometrial Neoplasms Estradiol 7.2418566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.2419155303 20544844 17893378 16202921
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.043659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.8211558140 3922381
MESH:D004827 Epilepsy Phenobarbital 2.8620417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.486401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.197750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.963659116
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.3812903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.3816530937
MESH:D005234 Fatty Liver arsenic trioxide 29.9415073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 29.9412795759 17595544 19224547 16239168 61145 16045604 12631006 15959796
MESH:D005234 Fatty Liver Dietary Fats 29.9419551842 18296743 19004024 17967931
MESH:D005234 Fatty Liver Ethinyl Estradiol 29.9415345470
MESH:D005234 Fatty Liver pirinixic acid 29.9420131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 29.9414986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1916709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4714745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.1219069698
MESH:D005355 Fibrosis Carbon Tetrachloride 8.6018705752
MESH:D005355 Fibrosis Dietary Fats 8.6018296743
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.2016904648
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.8716973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.2416417039
MESH:D006258 Head and Neck Neoplasms decitabine 3.4419215824
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.5720471113
MESH:D006330 Heart Defects, Congenital Vitamin E 6.5716080930
MESH:D006333 Heart Failure pirinixic acid 2.5020558911
MESH:D006505 Hepatitis Carbon Tetrachloride 3.5319110552 19900420
MESH:D006529 Hepatomegaly Phenobarbital 8.2716109766
MESH:D006529 Hepatomegaly pirinixic acid 8.2718467677 19772884 16221962 19176532
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 5.907520565
MESH:D006548 Hernia, Diaphragmatic Vitamin E 5.9016490937 16863852
MESH:D006558 Herpes Genitalis Estradiol 4.9815709030
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.6917440010
MESH:D019584 Hot Flashes Estradiol 9.8617088409
MESH:D019584 Hot Flashes Vitamin E 9.8614716179
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.4716899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.5321332399
MESH:D006943 Hyperglycemia pirinixic acid 3.1220558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.5521332399
MESH:D006973 Hypertension Dexamethasone 2.9117042910
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.0215338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7516569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4012013081
MESH:D007248 Infertility, Male decitabine 10.9817581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 10.9817937319
MESH:D007248 Infertility, Male vinclozolin 10.9816467254
MESH:D007249 Inflammation Dexamethasone 8.2111099482 8960868
MESH:D007249 Inflammation Dietary Fats 8.2120412841
MESH:D007249 Inflammation Tamoxifen 8.2119457130
MESH:D007251 Influenza, Human Vitamin E 4.1616624496
MESH:D007333 Insulin Resistance Dietary Fats 12.0411836018 18457598
MESH:D007333 Insulin Resistance Estradiol 12.0416627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 12.0416306350
MESH:D007674 Kidney Diseases Estradiol 5.9815618244
MESH:D007674 Kidney Diseases Vitamin E 5.9812488133
MESH:D007680 Kidney Neoplasms Estradiol 7.2015610895
MESH:D007680 Kidney Neoplasms Tamoxifen 7.2018625569
MESH:D007938 Leukemia arsenic trioxide 6.3415070760
MESH:D007938 Leukemia decitabine 6.3418980019 19235587
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.7317077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.2416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3814633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.3819077051
MESH:D007951 Leukemia, Myeloid decitabine 9.3817236224 19117987 18454857
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.9516968895 20471514 16467208 17050201 19850784
MESH:D015470 Leukemia, Myeloid, Acute decitabine 3.9518704418 19010910 19387464 18460780 18206229 17679729
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.4118055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.1717217047 16330433 12018890 17869043 11468182 16966277 12712474 11161223 15336539 12679006 16112521 19075265 16891316 19225113 19642359 15622746 9834237 15748426 15213294 16331271 17107899 17712046 16823087 17649720 19035177
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.2916882451
MESH:D007984 Leydig Cell Tumor vinclozolin 4.6716417039
MESH:D008064 Lipidoses Tamoxifen 3.1117567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.8216943688 16239168 11903743 16221502 11408273 21278145 17157831 17174718 17334410
MESH:D008103 Liver Cirrhosis Dietary Fats 10.8218296743
MESH:D008103 Liver Cirrhosis Phenobarbital 10.8221047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 10.8217708605 15931870 18376398 15057751 18054572 16638106 17714472 16011737 12445421 16027843 12632514 14620537 12546737 18205269 12898905 18263696 15730626 17922224 12389079 17766677 15338365 17976157 15876570 18472332 16248980 18472094 15673190 10355542 18251166 18481824 15818738 17869086 18156304 18166357 12445418 15123356 17805973 14748882 16015684 17565644 18395914 18395095 18210741 17900296 17823541 15052691 17525996 15959796 17557913 14716833 17761835 12609069 12666154 17944888 12958196 18317297 18412020 17721639 14512876 12632512 13678700 16192424 18418968 17631135 12667390 18705752 17640975 15996030 15370692 18279442 14716496 18429990 12741479 18277467 14724832 16116963 16033810 15650968 15893842 15925388 18420326 17481882 12586293 16136751 20821823 15362042 17698563 18339082 11481614 18187930 12649538 16097048 18006644
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 10.8216718785
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 10.8214716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Melatonin 10.8215298665 16703270 15925388
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 10.8215474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 10.8218564211
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 10.8216169303
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.0416246199 15830285 15720792 16964402 17285989
MESH:D008107 Liver Diseases Phenobarbital 4.0419363144
MESH:D017093 Liver Failure Carbon Tetrachloride 4.1015123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.6316899240 14706259
MESH:D008113 Liver Neoplasms Aflatoxin B1 21.5415890375 18177683 2125692 9163691
MESH:D008113 Liver Neoplasms arsenic trioxide 21.5414682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 21.5421137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 21.5419294768
MESH:D008113 Liver Neoplasms Phenobarbital 21.5419812893 8742319 21047994 15975961 19073162 19482888
MESH:D008113 Liver Neoplasms pirinixic acid 21.5420007298 16377806 15890375
MESH:D008113 Liver Neoplasms Tamoxifen 21.5416684651
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 13.808603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 13.8020377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 13.8012014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 13.801399818 2563599 17172636 6150874 18308698
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3015213294
MESH:D008171 Lung Diseases Vitamin E 3.1316863852
MESH:D008175 Lung Neoplasms Aflatoxin B1 10.6014755239
MESH:D008175 Lung Neoplasms arsenic trioxide 10.6019825857 11798837
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 10.6018816296 17053015 6695378 18569708 20064080 18520028 20869020 20464547 20135361
MESH:D008175 Lung Neoplasms Dexamethasone 10.6011195469 15824018
MESH:D008175 Lung Neoplasms Melatonin 10.6017195641
MESH:D008175 Lung Neoplasms Tamoxifen 10.6018625569
MESH:D008175 Lung Neoplasms Vitamin E 10.6011062179
MESH:D008180 Lupus Erythematosus, Systemic Melatonin 3.8916373423
MESH:D008223 Lymphoma decitabine 3.3719470736
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.7019428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 5.8317203775 16891317 11408345 11807958
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 5.8316827153 14580682 19196723 19196722 11731420
MESH:D020149 Manganese Poisoning Estradiol 12.4619453300
MESH:D020149 Manganese Poisoning Tamoxifen 12.4619453300
MESH:D008545 Melanoma decitabine 3.3616505122 17785578
MESH:D008545 Melanoma Tamoxifen 3.3612393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.1215990972
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.1416381670
MESH:D009101 Multiple Myeloma arsenic trioxide 11.9115949261 19417148 14977855 11468182 19549372
MESH:D009101 Multiple Myeloma decitabine 11.9118172295
MESH:D009101 Multiple Myeloma Dexamethasone 11.9115867202 16118317 15744524
MESH:D009135 Muscular Diseases pirinixic acid 3.4416239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.6218349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 12.1816882451 16105982
MESH:D009190 Myelodysplastic Syndromes decitabine 12.1818608210 19157545 19010910 16882708
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 12.189809623
MESH:D009203 Myocardial Infarction pirinixic acid 2.1119151258
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.0816810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.0816411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.4117484760
MESH:D009336 Necrosis Melatonin 5.4012195237
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.9016624393
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.5219393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4919410462
MESH:D009369 Neoplasms Benzo(a)pyrene 8.0411141357
MESH:D009369 Neoplasms decitabine 8.0419116145 19470736 17925555
MESH:D009369 Neoplasms pirinixic acid 8.0417405874
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.9419189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6717289903
MESH:D009421 Nervous System Malformations Estradiol 3.5916427766 11399458
MESH:D009436 Neural Tube Defects arsenic trioxide 3.0710525206
MESH:D009765 Obesity Dietary Fats 4.3816723640 18674790 18457598 11836018 21332399 20132043 17217161 20518802 19632207
MESH:D009765 Obesity pirinixic acid 4.3820558911
MESH:D010018 Osteomalacia Phenobarbital 4.3017016548
MESH:D010051 Ovarian Neoplasms arsenic trioxide 7.7912452020 16624393 19769630
MESH:D010051 Ovarian Neoplasms decitabine 7.7919331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 7.7919401270
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.5315580305
MESH:D010190 Pancreatic Neoplasms decitabine 8.5319294695
MESH:D010190 Pancreatic Neoplasms Phenobarbital 8.5316965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6211578682
MESH:D010235 Paraganglioma arsenic trioxide 4.1019927285
MESH:D020734 Parkinsonian Disorders Melatonin 4.9715574749
MESH:D010538 Peritonitis Melatonin 5.2515707874
MESH:D011230 Precancerous Conditions Phenobarbital 3.562563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.5121297632
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 3.8419015723 18220299 18042343
MESH:D055728 Primary Myelofibrosis decitabine 4.6617616702
MESH:D011469 Prostatic Diseases vinclozolin 4.8718220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.8220887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.8519131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.8517292933
MESH:D011471 Prostatic Neoplasms Estradiol 1.8516740699
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.8515067354
MESH:D011471 Prostatic Neoplasms Vitamin E 1.8515084515
MESH:D011472 Prostatitis vinclozolin 4.8718629315
MESH:D011537 Pruritus Ethinyl Estradiol 3.2516919318 15861022
MESH:D019310 Pseudolymphoma Phenobarbital 4.4412752131
MESH:D015427 Reperfusion Injury pirinixic acid 2.3519058328
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 3.9511700416 18379247
MESH:D012208 Rhabdomyosarcoma decitabine 4.3419155313
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.9016646077
MESH:D012640 Seizures Phenobarbital 2.6511442880 3137016 4039156 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.766407741
MESH:D012871 Skin Diseases Vitamin E 2.4218709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.6110029692 19755658
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 5.618532709
MESH:D012893 Sleep Disorders Melatonin 5.4018182647 16897403 16919138
MESH:D020178 Sleep Disorders, Circadian Rhythm Melatonin 6.5818078449 19452292
MESH:D007319 Sleep Initiation and Maintenance Disorders Melatonin 5.2018078449
MESH:D013088 Spermatocele Ethinyl Estradiol 11.3716709447
MESH:D013088 Spermatocele Tamoxifen 11.3716709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.9819457130
MESH:D013272 Stomach Diseases Dexamethasone 4.2615472012
MESH:D013274 Stomach Neoplasms marker/mechanism 16367923
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.3517007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.352093021 20155912
MESH:D013274 Stomach Neoplasms decitabine 3.3519037991
MESH:D013276 Stomach Ulcer Dexamethasone 7.7015138204
MESH:D013276 Stomach Ulcer Melatonin 7.7012500499 11523592 16150113
MESH:D020521 Stroke Vitamin E 3.4716517955
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0915669648
MESH:D013964 Thyroid Neoplasms arsenic trioxide 11.7319014326
MESH:D013964 Thyroid Neoplasms decitabine 11.7317967635
MESH:D013964 Thyroid Neoplasms Phenobarbital 11.731399818
MESH:D013978 Tibial Fractures Estradiol 4.6319048282
MESH:D016171 Torsades de Pointes arsenic trioxide 3.9015213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 11.7312973940 20435036 12845720 11780464
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 11.7317053015
MESH:D001749 Urinary Bladder Neoplasms decitabine 11.7317616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 11.738653321 17572228 16712894
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2314692618
MESH:D014604 Uveal Neoplasms decitabine 4.8617785578
MESH:D014605 Uveitis Dexamethasone 4.761336536
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4814671159 15869587
MESH:D015430 Weight Gain Dietary Fats 3.6816723640
Pathway ID Pathway Name
KEGG:04710 Circadian rhythm - mammal
REACT:71 Gene Expression
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA34630
    • No data
    Releated disease ID Related disease Name
    PA444437Hepatitis B
    Releated drug ID Related drug Name
    PA450163lamivudine
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB01990 - Cholesterol-Sulfate Anticarcinogenic Agents;Serine Proteinase Inhibitors
    DB04540 - Cholesterol
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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