AutismKB 2.0

Annotation Detail for RPL10


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Basic Information Top
Gene Symbol:RPL10 ( DKFZp686J1851,DXS648,DXS648E,FLJ23544,FLJ27072,NOV,QM )
Gene Full Name: ribosomal protein L10
Band: Xq28
Quick LinksEntrez ID:6134; OMIM: 312173; Uniprot ID:RL10_HUMAN; ENSEMBL ID: ENSG00000147403; HGNC ID: 10298
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa03010Ribosome
Pathway IDPathway Name
Diabetes pathways
Metabolism of proteins
Regulation of beta-cell development
Influenza Infection
Gene Expression
3' -UTR-mediated translational regulation
No data
No data
Pathway IDPathway Name
500526L13a-mediated translational silencing of Ceruloplasmin expression
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1831Prostate cancer
1934Cancer
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C019499 2-nitrofluorene 2-nitrofluorene results in increased expression of RPL10 mRNAincreases expression 15890375
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of RPL10 mRNAdecreases expression 12958071
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of RPL10 mRNAdecreases expression 18648102
C016583 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL10 mRNAincreases expression 15890375
D016604 Aflatoxin B1 Aflatoxin B1 results in increased expression of RPL10 mRNAincreases expression 15890375
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RPL10 mRNAaffects expression 16483693
D001280 Atrazine [Atrazine co-treated with Diuron co-treated with isoproturon] results in increased expression of RPL10 mRNAaffects cotreatment|increases expression 16532367
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RPL10 mRNAdecreases expression 19150397
C099555 CD 437 CD 437 results in decreased expression of RPL10 mRNAdecreases expression 12958071
D002713 Chlorine [Ozone co-treated with Chlorine] results in decreased expression of RPL10 mRNAaffects cotreatment|decreases expression 18636392
D020111 Chlorodiphenyl (54% Chlorine) Chlorodiphenyl (54% Chlorine) affects the expression of RPL10 mRNAaffects expression 12408591
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of RPL10 mRNAaffects cotreatment|affects expression 17602206
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of RPL10 mRNAaffects cotreatment|affects expression 17602206
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of RPL10 mRNAincreases expression 15890375
C444299 diindolylmethane diindolylmethane inhibits the reaction [Estradiol results in increased expression of RPL10 mRNA]decreases reaction|increases expression 11179685
C444299 diindolylmethane diindolylmethane promotes the reaction [Estradiol results in increased expression of RPL10 mRNA]increases expression|increases reaction 11179685
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased expression of RPL10 mRNAincreases expression 15890375
D004237 Diuron [Atrazine co-treated with Diuron co-treated with isoproturon] results in increased expression of RPL10 mRNAaffects cotreatment|increases expression 16532367
D004958 Estradiol diindolylmethane inhibits the reaction [Estradiol results in increased expression of RPL10 mRNA]decreases reaction|increases expression 11179685
D004958 Estradiol diindolylmethane promotes the reaction [Estradiol results in increased expression of RPL10 mRNA]increases expression|increases reaction 11179685
D004958 Estradiol Estradiol results in increased expression of RPL10 mRNAincreases expression 11179685
D004958 Estradiol Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of RPL10 mRNA]decreases reaction|increases expression 11179685
C028904 isoproturon [Atrazine co-treated with Diuron co-treated with isoproturon] results in increased expression of RPL10 mRNAaffects cotreatment|increases expression 16532367
D007657 Ketone Bodies Ketone Bodies results in increased expression of RPL10 mRNAincreases expression 15469884
D008701 Methapyrilene Methapyrilene results in increased expression of RPL10 mRNAincreases expression 15890375
D008748 Methylcholanthrene Methylcholanthrene affects the expression of RPL10 mRNAaffects expression 12408591
D010126 Ozone [Ozone co-treated with Chlorine] results in decreased expression of RPL10 mRNAaffects cotreatment|decreases expression 18636392
D017239 Paclitaxel RPL10 protein affects the susceptibility to Paclitaxelaffects response to substance 16217747
D010882 Piperonyl Butoxide Piperonyl Butoxide results in decreased expression of RPL10 mRNAdecreases expression 15890375
C006253 pirinixic acid pirinixic acid results in increased expression of RPL10 mRNAincreases expression 15890375
D018038 Sodium Selenite Sodium Selenite results in increased expression of RPL10 mRNAincreases expression 18175754
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of RPL10 mRNA]decreases reaction|increases expression 11179685
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of RPL10 proteindecreases expression 16548065
D014810 Vitamin E Vitamin E results in increased expression of RPL10 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.5915322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.3018287403
MESH:D055371 Acute Lung Injury Chlorine 8.3420601635
MESH:D055371 Acute Lung Injury pirinixic acid 8.3418653653
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 4.3816033868
MESH:D000230 Adenocarcinoma Estradiol 4.3811473722
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 19.443712494
MESH:D000236 Adenoma 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 19.4416176798
MESH:D000236 Adenoma Diethylnitrosamine 19.4410737359 6695378
MESH:D000236 Adenoma Dimethylnitrosamine 19.4419555203
MESH:D000236 Adenoma Methylcholanthrene 19.446695378 10545420
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 15.7517162532 16434500 18056438 19061943 19052882 17620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 15.7516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 15.7516835633
MESH:D000382 Agricultural Workers' Diseases Atrazine 3.9711874814
MESH:D000544 Alzheimer Disease Ozone 2.3815513908
MESH:D000686 Amyloidosis Diethylstilbestrol 4.2315469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7211748828
MESH:D001172 Arthritis, Rheumatoid Ozone 2.5015570426
MESH:D001249 Asthma Ozone 2.5617854713 16373670
MESH:D050197 Atherosclerosis Methylcholanthrene 3.3011922910
MESH:D001321 Autistic Disorder marker/mechanism 16940977
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.751440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 7.9919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 7.9912125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6015746008
MESH:D001859 Bone Neoplasms Paclitaxel 4.3215867366
MESH:D001943 Breast Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 3.6020146248
MESH:D001943 Breast Neoplasms Diethylnitrosamine 3.6017474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 3.6017129689 15324884
MESH:D001943 Breast Neoplasms Estradiol 3.6012948864 16675129 19861407 18497071 14630087 17261762 17018787 17289903
MESH:D001943 Breast Neoplasms Methylcholanthrene 3.6017474063
MESH:D001943 Breast Neoplasms Paclitaxel 3.6016115903 15136595 18234424 16273361 11325840 18323546 18223236 16244791
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.6020435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.4716777450 18417511 15516495 18315731 14754758 19059883 17626835
MESH:D002100 Cachexia Ozone 4.4816183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.2016111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.6716050911
MESH:D002277 Carcinoma Dimethylnitrosamine 12.8619555203
MESH:D002277 Carcinoma Methylcholanthrene 12.8610545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 12.8616835633
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 10.803581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 10.8012907637 21507988 12619106
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 10.8011831363 16698587 18506893 18691550 20007298 16935385 18785209 19701751 16807293 20214788 16540662 3084413 17173139 16681979 19394651 19052882 17138121 19919837 20524982 20727157 16830150 20514400 17761372 18788625 19335982 17055752 18978308 19107877 17978847 19418558 16288022 19539802 16779866 16569478 3581430 20432363 19171122 18393292 20935162 18210153 17428255 20101231 19519916 17162532 20084675 16502159 21159647 19383236 19822196 16328049 18494052 10737359 18056438 18971187 10672840 16878318 20512989 19208518 18665156
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 10.8016924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Estradiol 10.8016924424
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 10.8016313753
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.557296757
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 2.8816033868
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2218850075 18670907 16120746
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 19.207505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 19.2020889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 19.2017174075 21159647 7505956 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 19.2018566989
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 19.2016192471
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.5919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.5916835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 7.2019486331 9022650
MESH:D002779 Cholestasis pirinixic acid 7.2019176532
MESH:D019457 Chromosome Breakage Sodium Selenite 4.4915894690
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.9912621046 8697196 16354765 15340226 15668235
MESH:D015179 Colorectal Neoplasms Paclitaxel 2.4418802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8414669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4020055451 15322242 10048152
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.4019769572
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.3116002989 12952375
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.562524372 8970840 18759878 11298694 12868966 14531868 8156756 11906362
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3018249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.253621924 2952479
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.5616285004
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 3.9920387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.9917107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.1919279558
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 14.209022650 18289764 11289319 7440962 8291058 1440618 18692083 6679447 9328219 16192314 18648102 9653073 6482804
MESH:D056486 Drug-Induced Liver Injury Chlorodiphenyl (54% Chlorine) 14.2017851650
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 14.2019107877
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 14.208172417
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 14.2015131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 14.2020420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.5711462148
MESH:D004417 Dyspnea Chlorine 4.3620016425
MESH:C538011 Eales disease Vitamin E 4.449068938
MESH:D004487 Edema pirinixic acid 5.7712083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.7712711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.6418230668 15322242 16714409
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.4316402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 6.9816804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 6.9811473722 19148513 18566989
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.809294722 10568697
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.8516302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 9.863581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 9.8620426865
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 9.8617016578
MESH:D004938 Esophageal Neoplasms Paclitaxel 9.8616481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8211564622
MESH:D005234 Fatty Liver Diethylnitrosamine 6.9121071580 20387270
MESH:D005234 Fatty Liver pirinixic acid 6.9119236843 20131406
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.5015751030 16611131 16002989 16534752 16513791
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2011858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.756705139
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.6814633661 10962813
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 2.6920067830
MESH:D005739 Gas Poisoning Chlorine 4.7420016425
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.6816452187
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.797505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3310696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.1111294989 10048152
MESH:D006330 Heart Defects, Congenital Vitamin E 6.1116080930
MESH:D006333 Heart Failure pirinixic acid 2.3820558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1011000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.266705139
MESH:D006529 Hepatomegaly pirinixic acid 7.4116221962 19176532 18467677 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.4115340226 12621046 16120746
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6116863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 4.7615709030
MESH:D019584 Hot Flashes Estradiol 9.1617088409
MESH:D019584 Hot Flashes Vitamin E 9.1614716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.788697196 18606429 16354765 15340226 16959395
MESH:D006943 Hyperglycemia pirinixic acid 2.9620558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 9.9815034207
MESH:D006965 Hyperplasia Diethylstilbestrol 9.9812960047 14722030
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8118850075 18670907
MESH:D007021 Hypospadias Diethylstilbestrol 4.3216002989
MESH:D007246 Infertility Diethylstilbestrol 4.1015036965
MESH:D007248 Infertility, Male Atrazine 3.5412948887
MESH:D007249 Inflammation Diethylnitrosamine 4.4518785209
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.4512200463 12878042
MESH:D007251 Influenza, Human Vitamin E 3.9516624496
MESH:D007333 Insulin Resistance Estradiol 11.3316393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 11.3316306350
MESH:D007333 Insulin Resistance Sodium Selenite 11.3314714311
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.759022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1016580747
MESH:D007674 Kidney Diseases Estradiol 5.6115618244
MESH:D007674 Kidney Diseases Vitamin E 5.6112488133
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 11.246582329
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 11.2415003126 16762066 14681315
MESH:D007680 Kidney Neoplasms Estradiol 11.2415610895
MESH:D007859 Learning Disorders Diethylstilbestrol 3.8117184923
MESH:D008080 Liposarcoma Paclitaxel 4.5817353645
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.6818665156 20032147 19638242 18407596 18522880
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.039327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 6.3617640959 17348192 15161499 17196135 17201889 18210741 15504291 18672772 15842777 16544323 18637143 17465448 16009107 15479170 15798949 15298665 14643895 17881167 17724770 18237412 15733078 15067225 17203207 17198567 16570917 16042886 15744066 18239293 15793283 17719030 14568256 15942678 12925901 15081153 15723089 15138612 17534399 15577212 18567088 15086199 18371158 15571005 15383259 15492853 14726149 15099470 18629640 17666798 15591649 14659978 16603200 18364076 12918455 15864749 16270385 16627068 15366600 14709902 15339415 15763062 15369754 18095165 16169303 17036385 17432682
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.3614659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.3615474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.3612878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 6.3616169303
MESH:D008107 Liver Diseases Diethylnitrosamine 2.0417034775
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 4.1817457977
MESH:D008113 Liver Neoplasms 2-nitrofluorene 36.5115890375
MESH:D008113 Liver Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 36.5115890375
MESH:D008113 Liver Neoplasms Aflatoxin B1 36.519163691 2125692 15890375 18177683
MESH:D008113 Liver Neoplasms Clofibric Acid 36.5117602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 36.5118978307 21278145 19254457 12771043 2422723 21071580 19294768 19499222 18754104 12112319 20434301 19833225 20583210 20405173 19090486 21047994 20118626 19812893 19551842 20452335 19690152 19256749 20101389 10737359 19426721 19638242 18648771 9163691 19850985 19642983 15175105 20137499 15885732 2862719 18977376 16942905 18644402 19427195 20501860 20492335 19073162 21167192 19996281 19255062
MESH:D008113 Liver Neoplasms Diethylstilbestrol 36.5115890375 16712894
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 36.5115890375 3113478
MESH:D008113 Liver Neoplasms Methapyrilene 36.5115890375
MESH:D008113 Liver Neoplasms Piperonyl Butoxide 36.5119690152 18648771 20101389 15890375
MESH:D008113 Liver Neoplasms pirinixic acid 36.5120007298 15890375 16377806
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 36.5116984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 21.266587162 1399818 3712494 598648
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 21.268603461
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 21.2617942915 18775883 16842330 17174075 18544905 16267830 19126423 19004024 18079962 18282651 18164116 19539802 18308698 19009564 3124819 2563599 9362446 17854601 18253720 21159647 18093689 19519916
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 21.266150874 15603536 1848544
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 21.261399818 598648
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 21.2612151625
MESH:D008171 Lung Diseases Ozone 6.948266340 19066396
MESH:D008171 Lung Diseases Vitamin E 6.9416863852
MESH:D055370 Lung Injury Ozone 3.5920417186
MESH:D008175 Lung Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 12.3919931552 9255578 18813816 17139156 14755239 15172992 15893417 12438228 18508827 16401635 16061637
MESH:D008175 Lung Neoplasms Aflatoxin B1 12.3914755239
MESH:D008175 Lung Neoplasms Diethylnitrosamine 12.3920970405 21163286 6695378 20512841
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 12.3916061637 19555203 11884234
MESH:D008175 Lung Neoplasms Methylcholanthrene 12.3915390079 9230183 16271038 21163286 20970405 11893704 10545420 6695378 1399818 20512841 16337739 7750092 17909032
MESH:D008175 Lung Neoplasms Ozone 12.397614698 8597069
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 12.3911884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 12.3911062179
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.8915166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.2915700306
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 3.8214737004
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 3.8814749477
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.2516002989
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.4016891317 17203775 11408345 11807958
MESH:D020149 Manganese Poisoning Estradiol 4.2219453300
MESH:D008545 Melanoma Paclitaxel 2.5516342250 12040289 12025231
MESH:D008654 Mesothelioma Atrazine 3.421916698
MESH:D008679 Metaplasia Ozone 4.8410496685
MESH:D009101 Multiple Myeloma Paclitaxel 3.5014749477
MESH:D009135 Muscular Diseases pirinixic acid 3.2516239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.0319151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.5916810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.5916411023
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 8.933581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.939029167 3581430
MESH:D009362 Neoplasm Metastasis Paclitaxel 8.9315867366
MESH:D009369 Neoplasms Diethylstilbestrol 4.6115313581
MESH:D009369 Neoplasms pirinixic acid 4.6117405874
MESH:D009389 Neovascularization, Pathologic Estradiol 3.4717289903
MESH:D009421 Nervous System Malformations Diethylstilbestrol 14.9211399458
MESH:D009421 Nervous System Malformations Estradiol 14.9216427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 14.9214600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 2.756679447
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.1320387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.8520387270
MESH:D009765 Obesity pirinixic acid 1.7520558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.196482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.753988306
MESH:D010014 Osteolysis Paclitaxel 4.7215867366
MESH:D010051 Ovarian Neoplasms CD 437 7.5817474084
MESH:D010051 Ovarian Neoplasms Estradiol 7.5819401270
MESH:D010051 Ovarian Neoplasms Paclitaxel 7.5811161223
MESH:D010190 Pancreatic Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 5.2912384795
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.2916540662
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.237296757
MESH:D010300 Parkinson Disease Atrazine 3.1817218051
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9812520081
MESH:D010538 Peritonitis Ozone 3.8716369182
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.206228378
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.9014722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.4116977796 15687265
MESH:D011014 Pneumonia Ozone 4.1318381685 18929643 18007984
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3118163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.332563599
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 8.6917184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.6911222880 11118676 11896295 11399792
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.6520887781
MESH:D011471 Prostatic Neoplasms marker/mechanism 17013881
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 1.9015046698 15846301 17136230
MESH:D011471 Prostatic Neoplasms Estradiol 1.9016740699
MESH:D011471 Prostatic Neoplasms Paclitaxel 1.9017172428 16356831 17136230 16729912
MESH:D011471 Prostatic Neoplasms Sodium Selenite 1.9018760546
MESH:D011471 Prostatic Neoplasms Vitamin E 1.9015084515
MESH:D015427 Reperfusion Injury pirinixic acid 2.2619058328
MESH:D012120 Respiration Disorders Chlorine 4.9518579056
MESH:D012135 Respiratory Sounds Atrazine 4.2611874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5918990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.183692021
MESH:D012871 Skin Diseases Vitamin E 2.3718709164
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 1.9216192470
MESH:D013088 Spermatocele Diethylstilbestrol 4.4516002989 16709447
MESH:D013158 Splenic Diseases Dimethylnitrosamine 5.0012587719
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.3918456281
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 3.3916033868
MESH:D013274 Stomach Neoplasms Paclitaxel 3.3918506536 18396642
MESH:D020521 Stroke Vitamin E 3.3216517955
MESH:D024801 Tauopathies Paclitaxel 4.5516930453
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6412697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 6.463712494 1399818 6587162 6582329 7505956
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 6.467505956
MESH:D013978 Tibial Fractures Estradiol 4.4219048282
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 7.888074119
MESH:D001749 Urinary Bladder Neoplasms CD 437 7.8816720286
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 7.8816712894 16452187 17306315
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 3.8116175088
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.9014652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 3.8215809267 16690809
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.1816513791 16002989
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3312125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9815886252
Pathway ID Pathway Name
REACT:1762 3' -UTR-mediated translational regulation
REACT:15380 Diabetes pathways
REACT:71 Gene Expression
REACT:6167 Influenza Infection
REACT:17015 Metabolism of proteins
REACT:13698 Regulation of beta-cell development
KEGG:03010 Ribosome
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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