AutismKB 2.0

Annotation Detail for RPL17


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Basic Information Top
Gene Symbol:RPL17 ( FLJ92089,MGC117162,rpL23 )
Gene Full Name: ribosomal protein L17
Band: 18q21.1
Quick LinksEntrez ID:6139; OMIM: 603661; Uniprot ID:RL17_HUMAN; ENSEMBL ID: ENSG00000215472; HGNC ID: 10307
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa03010Ribosome
Pathway IDPathway Name
Diabetes pathways
Metabolism of proteins
Regulation of beta-cell development
Influenza Infection
Gene Expression
3' -UTR-mediated translational regulation
No data
No data
Pathway IDPathway Name
500526L13a-mediated translational silencing of Ceruloplasmin expression
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of RPL17 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of RPL17 mRNAaffects expression 21346803
C019499 2-nitrofluorene 2-nitrofluorene results in increased expression of RPL17 mRNAincreases expression 15890375
C016583 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL17 mRNAincreases expression 15890375
D016604 Aflatoxin B1 Aflatoxin B1 results in increased expression of RPL17 mRNAincreases expression 15890375
D000638 Amiodarone Amiodarone affects the expression of RPL17 mRNAaffects expression 19483382
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RPL17 mRNAaffects expression 16483693
C058317 arsenic disulfide arsenic disulfide results in decreased expression of RPL17 mRNAdecreases expression 12890387
C006632 arsenic trioxide arsenic trioxide results in decreased expression of RPL17 mRNAdecreases expression 12852829
C006632 arsenic trioxide arsenic trioxide results in increased expression of RPL17 mRNAincreases expression 20458559
D001553 Benzbromarone Benzbromarone affects the expression of RPL17 mRNAaffects expression 19483382
D002994 Clofibrate Clofibrate affects the expression of RPL17 mRNAaffects expression 19483382
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of RPL17 mRNAincreases expression 17942915
D004052 Diethylnitrosamine MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RPL17 mRNA]decreases reaction|increases expression 17942915
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of RPL17 mRNAincreases expression 15890375
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased expression of RPL17 mRNAincreases expression 15890375
D005001 Ethionine Ethionine affects the expression of RPL17 mRNAaffects expression 19483382
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of RPL17 mRNAaffects cotreatment|increases expression 17183730
D008701 Methapyrilene Methapyrilene results in increased expression of RPL17 mRNAincreases expression 15890375
D009853 Omeprazole Omeprazole affects the expression of RPL17 mRNAaffects expression 19483382
D010882 Piperonyl Butoxide Piperonyl Butoxide results in increased expression of RPL17 mRNAincreases expression 15890375
C006253 pirinixic acid pirinixic acid affects the expression of RPL17 mRNAaffects expression 19483382
C006253 pirinixic acid pirinixic acid results in increased expression of RPL17 mRNAincreases expression 15890375
D011441 Propylthiouracil Propylthiouracil affects the expression of RPL17 mRNAaffects expression 19483382
D018038 Sodium Selenite Sodium Selenite results in increased expression of RPL17 mRNAincreases expression 18175754
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of RPL17 mRNAaffects binding|increases expression 16214954
D013853 Thioacetamide Thioacetamide affects the expression of RPL17 mRNAaffects expression 19483382
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of RPL17 mRNAaffects cotreatment|increases expression 17183730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.6714514962 15322242 11752688
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 7.678875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.7519490988
MESH:D000138 Acidosis Ammonium Chloride 3.3718287403
MESH:D055371 Acute Lung Injury pirinixic acid 2.9418653653
MESH:D000230 Adenocarcinoma arsenic trioxide 4.5219825857 11798837
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 4.5216033868
MESH:D000236 Adenoma 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 10.7716176798
MESH:D000236 Adenoma Diethylnitrosamine 10.776695378 10737359
MESH:D000236 Adenoma Dimethylnitrosamine 10.7719555203
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 16.1618056438 16434500 17162532 19061943 17620307 19052882
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.1616434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.1616835633
MESH:D000550 Amblyopia Valproic Acid 5.0417688650
MESH:D000686 Amyloidosis Diethylstilbestrol 4.3015469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7811748828
MESH:D001008 Anxiety Disorders Valproic Acid 3.4217497229
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.6420041841 18218290 18057881
MESH:D001281 Atrial Fibrillation Amiodarone 3.7619698954 18651412
MESH:D001321 Autistic Disorder Valproic Acid 2.0217688650 18985861 20603192 18316065 18775368 17157402 18396377 18558336 15238991 17507914 16609825 19460635 18177632 19232924 18940202
MESH:D001714 Bipolar Disorder Valproic Acid 2.9820046352 17594078
MESH:D001778 Blood Coagulation Disorders Amiodarone 62.6019483382
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 62.6016206674
MESH:D001778 Blood Coagulation Disorders Benzbromarone 62.6019483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 62.6019483382
MESH:D001778 Blood Coagulation Disorders Ethionine 62.6019483382
MESH:D001778 Blood Coagulation Disorders Omeprazole 62.6019483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 62.6019483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 62.6019483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 62.6012125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 62.6019483382
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6015340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.6215746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.628888407
MESH:D001943 Breast Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 1.9720146248
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.9717474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 1.9715324884 17129689
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9720435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1511589617
MESH:D002277 Carcinoma Dimethylnitrosamine 7.8519555203
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.8516835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 16.3816705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 16.3816705839
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 16.3812907637 12619106 21507988
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 16.3814691202 15073043 16217749 15553829 11135700
MESH:D006528 Carcinoma, Hepatocellular Benzbromarone 16.381701930
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 16.3816681979 17162532 17761372 18971187 16540662 19519916 10672840 18665156 20727157 17428255 16878318 21159647 18056438 16807293 19919837 20007298 17978847 19335982 19701751 19539802 18978308 10737359 18788625 18785209 16935385 20101231 16830150 19107877 18506893 19383236 20432363 19822196 17138121 18210153 19171122 20084675 18691550 3084413 16569478 20512989 18494052 19052882 19208518 20524982 17173139 18393292 20214788 3581430 16698587 19418558 16288022 16779866 16502159 11831363 17055752 20935162 20514400 19394651 16328049
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 16.3816924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 16.3817997003
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.6819014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9512490120
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 2.9016033868
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2616120746 18850075 18670907
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.8315710769 19225199
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.8918974383
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 10.536135515
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 10.531399818
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 10.537505956 17174075 21159647 2727394
MESH:D002637 Chest Pain Omeprazole 4.9115447763
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.6420734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 15.1919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 15.1916835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 15.1918291259
MESH:D002779 Cholestasis pirinixic acid 2.6919176532
MESH:D019457 Chromosome Breakage Sodium Selenite 4.5615894690
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0312621046 15340226 16354765 8697196 15668235
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9014669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 4.0012609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.6510525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.6520055451 15322242 10048152
MESH:D019465 Craniofacial Abnormalities Valproic Acid 3.6517688650 8888407 16575769
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.3716002989 12952375
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.2618551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.2618551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9215213294
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3418249437
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.6216285004
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.0620387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.0617107852
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 24.8318551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 24.8318551238 21346803
MESH:D056486 Drug-Induced Liver Injury Amiodarone 24.8315265979 18218290
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 24.8319107877
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 24.838172417
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 24.8315131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 24.8320420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 24.8312963478
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 24.831733752 19641884
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6211462148
MESH:D004381 Duodenal Ulcer Omeprazole 4.1517151854 15991576 16613094 21218061
MESH:D050171 Dyslipidemias Clofibrate 3.9316707586
MESH:D004421 Dystonia Valproic Acid 3.871851702
MESH:D004487 Edema pirinixic acid 5.9712083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.9711000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7115322242 16714409 18230668
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.5016402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 3.3415700306 16804899
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.8610568697 9294722
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 3.963659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 3.7216628512 3922381
MESH:D004827 Epilepsy Valproic Acid 2.8420417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.436426943 7562514 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.117750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.873659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9216302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.6012903497
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 4.6017016578
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8711564622
MESH:D005218 Fat Necrosis Thioacetamide 5.5316456712
MESH:D005234 Fatty Liver Amiodarone 28.4714986274
MESH:D005234 Fatty Liver arsenic trioxide 28.4715073043
MESH:D005234 Fatty Liver Clofibrate 28.4719224547
MESH:D005234 Fatty Liver Diethylnitrosamine 28.4720387270 21071580
MESH:D005234 Fatty Liver pirinixic acid 28.4720131406 19236843
MESH:D005234 Fatty Liver Valproic Acid 28.4719224547 14986274
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.5416611131 16002989 16513791 16534752 15751030
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2711858732
MESH:D005315 Fetal Diseases Valproic Acid 4.6916575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.9518558336 8888407
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 2.7620067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.0816904648
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.7516452187
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4010696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2310048152 11294989
MESH:D006333 Heart Failure pirinixic acid 2.4220558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1611000095
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.4018665440 15929193 17276928
MESH:D006505 Hepatitis Thioacetamide 4.0316456712
MESH:D006529 Hepatomegaly Amiodarone 13.3215265979
MESH:D006529 Hepatomegaly pirinixic acid 13.3216221962 19176532 18467677 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 13.3215340226 16120746 12621046
MESH:D006849 Hydrocephalus Valproic Acid 4.6717688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.858697196 15340226 16959395 18606429 16354765
MESH:D006937 Hypercholesterolemia Amiodarone 3.708137927 9751232
MESH:D006943 Hyperglycemia pirinixic acid 3.0220558911
MESH:D006965 Hyperplasia Diethylstilbestrol 4.2514722030 12960047
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8418670907 18850075
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.4416612254
MESH:D007021 Hypospadias Diethylstilbestrol 4.3916002989
MESH:D007037 Hypothyroidism Amiodarone 10.9817991464 18020914
MESH:D007037 Hypothyroidism Propylthiouracil 10.9818031379 8137927
MESH:D007246 Infertility Diethylstilbestrol 4.1715036965
MESH:D007249 Inflammation Diethylnitrosamine 4.5718785209
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.5712200463 12878042
MESH:D007333 Insulin Resistance pirinixic acid 6.9016306350
MESH:D007333 Insulin Resistance Sodium Selenite 6.9014714311
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1616580747
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 11.5616705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 11.5616705839
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 11.5614681315 15003126 16762066
MESH:D007859 Learning Disorders Diethylstilbestrol 3.8717184923
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 3.9419248655
MESH:D007938 Leukemia arsenic trioxide 2.7415070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.6212560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.1116972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic disulfide 8.4512421474
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 8.4514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.5919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.7916467208 19850784 17050201 16968895 20471514
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 3.7917596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.0915748426 17869043 19075265 15622746 17107899 16823087 16331271 11161223 9834237 12018890 15336539 17649720 11468182 19225113 17712046 15213294 19035177 16966277 17217047 12679006 12712474 16891316 19642359 16330433 16112521
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.1716882451
MESH:D008064 Lipidoses Amiodarone 3.3717567588 15342952
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.7219638242 18665156 18407596 18522880 20032147
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 4.7917203207 17348192 14659978 16627068 18637143 14568256 17881167 15571005 15591649 18672772 16169303 17666798 15793283 17719030 15161499 18095165 15504291 15479170 16570917 15099470 15798949 15492853 16603200 15298665 18237412 15067225 15577212 14709902 18210741 17724770 18629640 14726149 18567088 16042886 17198567 15942678 15723089 12918455 15138612 16009107 15744066 15842777 15086199 15864749 17534399 15733078 18239293 17640959 17196135 15339415 16270385 17036385 12925901 17432682 14643895 15763062 17465448 15369754 16544323 17201889 18371158 15366600 18364076 15081153 15383259
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.7915474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.7912878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 4.7912891558 15158331 15474484 18380797 18395095 16343077 10677585 15288472 16097051 16126171 15334695 15078482 15288473 16248980 12531686 12175628 18416461 18458672 17127702 17355460 11172339 11682029 15075984 18295389 15316131 15362042 11481614 18031379 18606216 17292413 16489207 15465738 12679928 17629604 18032466 15716488 17050028 15095483 18615449 12557150 14739098 12085344 16511523 16098781 18263696
MESH:D008107 Liver Diseases Diethylnitrosamine 4.1317034775
MESH:D008107 Liver Diseases Thioacetamide 4.1315158337 16337175 18374380
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 9.5117457977
MESH:D017114 Liver Failure, Acute Thioacetamide 9.5115313186 12479984 15633222 17276928
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 41.697678174
MESH:D008113 Liver Neoplasms 2-nitrofluorene 41.6915890375
MESH:D008113 Liver Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 41.6915890375
MESH:D008113 Liver Neoplasms Aflatoxin B1 41.6915890375 9163691 2125692 18177683
MESH:D008113 Liver Neoplasms arsenic trioxide 41.6914682389
MESH:D008113 Liver Neoplasms Diethylnitrosamine 41.692422723 19812893 9163691 20101389 20405173 21278145 20434301 2862719 19090486 18977376 21047994 19254457 18644402 15885732 19850985 19499222 20492335 19426721 19256749 12112319 20118626 21167192 16942905 19642983 19551842 19996281 18754104 18648771 18978307 19255062 19073162 21071580 20501860 19294768 19833225 20583210 10737359 20452335 19427195 15175105 19690152 12771043 20137499 19638242
MESH:D008113 Liver Neoplasms Diethylstilbestrol 41.6915890375 16712894
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 41.693113478 15890375
MESH:D008113 Liver Neoplasms Methapyrilene 41.6915890375
MESH:D008113 Liver Neoplasms Piperonyl Butoxide 41.6920101389 19690152 18648771 15890375
MESH:D008113 Liver Neoplasms pirinixic acid 41.6916377806 20007298 15890375
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 41.6916984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 21.842876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 21.848603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 21.8420377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 21.8418253720 19539802 19126423 18775883 18093689 18282651 2563599 16842330 17942915 16267830 18164116 19009564 21159647 18308698 17174075 19519916 17854601 18079962 3124819 19004024 9362446 18544905
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 21.8415603536 6150874 1848544
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 21.8412151625
MESH:D008133 Long QT Syndrome Amiodarone 7.7115350150 17391786 11989578
MESH:D008133 Long QT Syndrome arsenic trioxide 7.7115213294
MESH:D008171 Lung Diseases Amiodarone 3.2512587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 10.6218516814
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 10.6217228818
MESH:D008175 Lung Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 8.2514755239 15893417 9255578 17139156 19931552 18813816 18508827 15172992 16061637 12438228 16401635
MESH:D008175 Lung Neoplasms Aflatoxin B1 8.2514755239
MESH:D008175 Lung Neoplasms arsenic trioxide 8.2519825857 11798837
MESH:D008175 Lung Neoplasms Diethylnitrosamine 8.2520970405 20512841 6695378 21163286
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 8.2516061637 19555203 11884234
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.2511884234 19555203
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.9615166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.3415700306
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 3.8814737004
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.3216002989
MESH:D008881 Migraine Disorders Valproic Acid 3.0618765137 18803445
MESH:D009101 Multiple Myeloma arsenic trioxide 2.9719417148 14977855 11468182 19549372 15949261
MESH:D009135 Muscular Diseases pirinixic acid 3.3216239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.858888407
MESH:D009181 Mycoses Amiodarone 4.7117974566 12754197
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.4818349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.0616105982 16882451
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 7.0617596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.0719151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8712213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8016411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 9.7118551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 9.7118551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.7816624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.493581430 9029167
MESH:D009369 Neoplasms Diethylstilbestrol 4.7315313581
MESH:D009369 Neoplasms pirinixic acid 4.7317405874
MESH:D009421 Nervous System Malformations Diethylstilbestrol 9.0311399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.0314600291
MESH:D009436 Neural Tube Defects arsenic trioxide 6.9210525206
MESH:D009436 Neural Tube Defects Valproic Acid 6.928888407 16359493
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.1920387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9220387270
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 4.759802331
MESH:D009765 Obesity pirinixic acid 1.7720558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 8.3316049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.3316049721
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.3516624393 12452020 19769630
MESH:D010190 Pancreatic Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 8.3412384795
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.3415580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.3416540662
MESH:D010235 Paraganglioma arsenic trioxide 3.9819927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0612520081
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.9814722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.4815687265 16977796
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3718163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.392563599
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 15.1517184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 15.1511118676 11399792 11896295 11222880
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 15.1520603192
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.7019131511
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.7015046698 17136230 15846301
MESH:D011471 Prostatic Neoplasms Sodium Selenite 2.7018760546
MESH:D019310 Pseudolymphoma Valproic Acid 4.3512752131 11422049
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.7812490602 11597910 12832656
MESH:D015427 Reperfusion Injury pirinixic acid 2.2919058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6518990726
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.0019155313
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.7816646077
MESH:D012559 Schizophrenia Valproic Acid 2.0415737665 19110320
MESH:D012640 Seizures 2,4-dinitrotoluene 9.0718551238
MESH:D012640 Seizures 2,6-dinitrotoluene 9.0718551238
MESH:D012640 Seizures Valproic Acid 9.071511512 16876388 3137016 15475178 11738929 17978042 11044598 14763951
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.8918724381
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 1.9616192470
MESH:D013088 Spermatocele Diethylstilbestrol 4.5216709447 16002989
MESH:D016135 Spinal Dysraphism Valproic Acid 3.6319490988
MESH:D013158 Splenic Diseases Dimethylnitrosamine 5.0812587719
MESH:D013226 Status Epilepticus Valproic Acid 4.3512833885
MESH:D013272 Stomach Diseases Omeprazole 4.4218545984
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.3517007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.3518456281
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 3.3516033868
MESH:D013276 Stomach Ulcer Amiodarone 7.0118087811
MESH:D013276 Stomach Ulcer Omeprazole 7.0111906479 15991576 16755016 18237397 10750652 17977527
MESH:D013610 Tachycardia Amiodarone 4.1111238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.0119225199
MESH:D013959 Thyroid Diseases Amiodarone 11.4119731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 11.4112697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 11.2319014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 11.237505956
MESH:D013964 Thyroid Neoplasms Propylthiouracil 11.2315710170
MESH:D013971 Thyrotoxicosis Amiodarone 4.6718020914 19584973
MESH:D016171 Torsades de Pointes Amiodarone 9.6211989578 17467628
MESH:D016171 Torsades de Pointes arsenic trioxide 9.6215213294
MESH:D014178 Translocation, Genetic Valproic Acid 5.0417262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.333119515
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 11.3216049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 11.3216049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 11.3212845720 11780464 20435036 12973940
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 11.3216712894 16452187 17306315
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.458888407
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.3510091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.3510091137
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 3.8716175088
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.9814652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 3.8915809267 16690809
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.2516002989 16513791
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4012125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0615886252
Pathway ID Pathway Name
REACT:1762 3' -UTR-mediated translational regulation
REACT:15380 Diabetes pathways
REACT:71 Gene Expression
REACT:6167 Influenza Infection
REACT:17015 Metabolism of proteins
REACT:13698 Regulation of beta-cell development
KEGG:03010 Ribosome
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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