AutismKB 2.0

Annotation Detail for RPS16


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Basic Information Top
Gene Symbol:RPS16 ( - )
Gene Full Name: ribosomal protein S16
Band: 19q13.1
Quick LinksEntrez ID:6217; OMIM: 603675; Uniprot ID:RS16_HUMAN; ENSEMBL ID: ENSG00000105193; HGNC ID: 10396
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa03010Ribosome
Pathway IDPathway Name
Diabetes pathways
Metabolism of proteins
Regulation of beta-cell development
Influenza Infection
Gene Expression
3' -UTR-mediated translational regulation
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of RPS16 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RPS16 mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of RPS16 mRNAdecreases expression 20504355
C099555 CD 437 CD 437 results in decreased expression of RPS16 mRNAdecreases expression 12958071
D004041 Dietary Fats Dietary Fats results in decreased expression of RPS16 mRNAdecreases expression 15238619
D015741 Metribolone Metribolone promotes the reaction [NDRG1 protein binds to RPS16 protein]affects binding|increases reaction 17220478
C017947 sodium arsenite sodium arsenite results in increased expression of RPS16 mRNAincreases expression 19072884
D018038 Sodium Selenite Sodium Selenite results in increased expression of RPS16 mRNAincreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.9018287403
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0320127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.786695378
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 5.0815276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 5.2816712894 17306315
MESH:D000799 Angioedema Acetaminophen 4.2210982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.3819183758
MESH:D001161 Arteriosclerosis Dietary Fats 4.1915238619
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0820146248 17474063
MESH:D001943 Breast Neoplasms Dietary Fats 2.0820435547
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.993084413
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 2.9917306315 15276417 16507464
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.8020419170
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 4.8018572023
MESH:D002386 Cataract Acetaminophen 2.7110977129
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 3.1420056578 19524636
MESH:D019457 Chromosome Breakage Sodium Selenite 5.0615894690
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.9916285004
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.0316109766 19370779 19085960 17562736 16081117 17522070 19739265 11834606 11461765 14550746 12705907 10774834 14725611 15619225 19416960 16227642 17906064 19923254 10663392 12540782 16781746 19420014 15968718 2444490 18713872 12958197 10915739 14986274 18071297 12153990 11287661 11529661 16177239 12594235 16393943 11743745 11421492 12392966 19164858 11739529 16485898
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 4.0315131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.4719426721
MESH:D050171 Dyslipidemias Dietary Fats 3.6218367378
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0616530937
MESH:D005234 Fatty Liver Dietary Fats 3.4819551842 19004024 17967931 18296743
MESH:D005355 Fibrosis Dietary Fats 3.8318296743
MESH:D005756 Gastritis Acetaminophen 4.0516983495
MESH:D005833 Genital Neoplasms, Female sodium arsenite 5.0216452187
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.7720471113
MESH:D006689 Hodgkin Disease sodium arsenite 3.3612676792
MESH:D006930 Hyperalgesia Acetaminophen 2.8916870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.8321332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.8721332399
MESH:D007248 Infertility, Male sodium arsenite 3.1412646999 15346721
MESH:D007249 Inflammation Dietary Fats 2.5420412841
MESH:D007333 Insulin Resistance Dietary Fats 7.9811836018 18457598
MESH:D007333 Insulin Resistance Sodium Selenite 7.9814714311
MESH:D007674 Kidney Diseases Acetaminophen 6.3912587719 15629191
MESH:D007674 Kidney Diseases sodium arsenite 6.3920008137
MESH:D008103 Liver Cirrhosis Dietary Fats 2.9918296743
MESH:D008107 Liver Diseases Acetaminophen 1.6712969438 19460945 16611625 19014921 19784758 16610002 11587558 12587719
MESH:D017114 Liver Failure, Acute Acetaminophen 3.4616871587 17185352
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.8321137059 20195826
MESH:D008113 Liver Neoplasms sodium arsenite 4.8315276417 16712894
MESH:D008171 Lung Diseases sodium arsenite 3.3219095001
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.486695378 20064080 20135361 20464547 18569708 20869020 18816296 17053015 18520028
MESH:D008175 Lung Neoplasms sodium arsenite 2.4815276417 17077188 17306315 19931552 16712894
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.3214737004
MESH:D008545 Melanoma sodium arsenite 2.0619082730 16487513
MESH:D008546 Melanoma, Experimental Acetaminophen 3.8719513568
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.3716381670
MESH:D009369 Neoplasms Benzo(a)pyrene 5.3811141357
MESH:D009369 Neoplasms sodium arsenite 5.3811559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.9720056578
MESH:D009436 Neural Tube Defects sodium arsenite 3.2912854658
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.0718514411
MESH:D009765 Obesity Dietary Fats 2.3317217161 18674790 16723640 21332399 19632207 11836018 18457598 20132043 20518802
MESH:D010051 Ovarian Neoplasms CD 437 5.4517474084
MESH:D010051 Ovarian Neoplasms sodium arsenite 5.4515276417 17306315
MESH:D010146 Pain Acetaminophen 2.5916870215
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.5217292933
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.5216039940
MESH:D011471 Prostatic Neoplasms Sodium Selenite 2.5218760546
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 6.0510029692 19755658
MESH:D012878 Skin Neoplasms sodium arsenite 6.0518572023 19524636
MESH:D016135 Spinal Dysraphism sodium arsenite 3.9812854658
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.5620155912 2093021
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 8.9217053015
MESH:D001749 Urinary Bladder Neoplasms CD 437 8.9216720286
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 8.9216452187 17306315 11723127 16712894
MESH:D014581 Urticaria Acetaminophen 3.2410982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.9911813266
MESH:D014652 Vascular Diseases sodium arsenite 4.7617056641
MESH:D015430 Weight Gain Dietary Fats 3.9516723640
Pathway ID Pathway Name
REACT:1762 3' -UTR-mediated translational regulation
REACT:15380 Diabetes pathways
REACT:71 Gene Expression
REACT:6167 Influenza Infection
REACT:17015 Metabolism of proteins
REACT:13698 Regulation of beta-cell development
KEGG:03010 Ribosome
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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