AutismKB 2.0

Annotation Detail for RRBP1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RRBP1 ( DKFZp586A1420,ES/130,ES130,FLJ36146,MGC157720,MGC157721,hES )
Gene Full Name: ribosome binding protein 1 homolog 180kDa (dog)
Band: 20p12.1
Quick LinksEntrez ID:6238; OMIM: 601418; Uniprot ID:RRBP1_HUMAN; ENSEMBL ID: ENSG00000125844; HGNC ID: 10448
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04141Protein processing in endoplasmic reticulum
No data
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of RRBP1 mRNAaffects expression 17562736
C006632 arsenic trioxide arsenic trioxide results in increased expression of RRBP1 mRNAincreases expression 15761015
D016572 Cyclosporine Cyclosporine results in increased expression of RRBP1 mRNAincreases expression 20106945
D004041 Dietary Fats Dietary Fats results in increased expression of RRBP1 mRNAincreases expression 18042831
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of RRBP1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RRBP1 mRNAaffects cotreatment|increases expression 17942748
D005472 Fluorouracil Fluorouracil results in decreased expression of RRBP1 proteindecreases expression 15352031
D005472 Fluorouracil RRBP1 protein affects the susceptibility to Fluorouracilaffects response to substance 15352031
C041786 palm oil palm oil results in increased expression of RRBP1 mRNAincreases expression 18042831
C006253 pirinixic acid pirinixic acid results in decreased expression of RRBP1 mRNAdecreases expression 17426115
D012643 Selenium [Selenium co-treated with Vitamin E] results in decreased expression of RRBP1 mRNAaffects cotreatment|decreases expression 19244175
C009277 sodium arsenate sodium arsenate results in increased expression of RRBP1 mRNAincreases expression 16882884
C004648 testosterone enanthate testosterone enanthate affects the expression of RRBP1 mRNAaffects expression 17440010
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of RRBP1 mRNAdecreases expression 18495758
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RRBP1 mRNAaffects cotreatment|increases expression 17942748
D014212 Tretinoin Tretinoin results in increased expression of RRBP1 mRNAincreases expression 16054129
D014635 Valproic Acid Valproic Acid results in increased expression of RRBP1 mRNAincreases expression 19101580
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in decreased expression of RRBP1 mRNAaffects cotreatment|decreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.4814514962 11752688 15322242
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 8.488875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.9619490988
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0017505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.1518653653
MESH:D000230 Adenocarcinoma arsenic trioxide 7.1311798837 19825857
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 7.1314692618
MESH:D000230 Adenocarcinoma Fluorouracil 7.1317638652
MESH:D018248 Adenoma, Liver Cell pirinixic acid 10.0716434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.0716835633
MESH:D000505 Alopecia Tretinoin 3.6415955085
MESH:D000550 Amblyopia Valproic Acid 5.3017688650
MESH:D000740 Anemia Fluorouracil 8.7716511603 17963324 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.7711748828
MESH:D000799 Angioedema Acetaminophen 3.9110982225
MESH:D001008 Anxiety Disorders Valproic Acid 3.5917497229
MESH:D001161 Arteriosclerosis Dietary Fats 10.0515238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 10.0511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.2615885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.2616412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2716292516
MESH:D001249 Asthma Tretinoin 2.3516456186
MESH:D001321 Autistic Disorder Acetaminophen 1.8518445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8516609825 20603192 17688650 18940202 19232924 18985861 18775368 15238991 17157402 18558336 18316065 17507914 18396377 18177632 19460635
MESH:D001471 Barrett Esophagus Tretinoin 4.4416935849
MESH:D001714 Bipolar Disorder Valproic Acid 3.0920046352 17594078
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 22.2116206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 22.2119483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 22.2112125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 22.2116206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 8.0815746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 8.088888407
MESH:D001943 Breast Neoplasms Dietary Fats 1.9520435547
MESH:D001943 Breast Neoplasms Fluorouracil 1.9516595493 19217205 16110121 16557594 18357371 15136595 18608205
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9520435547
MESH:D001943 Breast Neoplasms Tretinoin 1.9516166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.6416813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.3611589617
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.9716050911
MESH:D002276 Carcinoid Tumor Fluorouracil 4.7316051944
MESH:D002277 Carcinoma Fluorouracil 8.2617121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 8.2616835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.2216168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 6.613084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 6.6111135700 14691202 15073043 15553829 16217749
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 6.6116332177 17971768 17045692 16799960 18930000 17088986
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 6.611917145
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.9419014326
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 3.0318695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.1412490120
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 4.7516280240 17066447 18986760 16757204
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.7516096774 16051514
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3818850075 16120746 18670907
MESH:D002386 Cataract Acetaminophen 7.2810977129
MESH:D002386 Cataract Tretinoin 7.2817460283
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.5412371664
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.6416129372
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.7220734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1916835633
MESH:D002779 Cholestasis Cyclosporine 13.4719486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.4716105132 17333356 16919318 11677210 17681005 17110522 15861022
MESH:D002779 Cholestasis pirinixic acid 13.4719176532
MESH:D002822 Choriocarcinoma Tretinoin 5.2216461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.8015668235 8697196 15340226 16354765 12621046
MESH:D002972 Cleft Palate Tretinoin 5.809407595
MESH:D003092 Colitis Selenium 9.6417936198
MESH:D003092 Colitis Tretinoin 9.6417035595
MESH:D003110 Colonic Neoplasms Fluorouracil 2.2417018589 17169374 17725105 15001691 18772588 16510598 17172411 17016597 16340194 17287894
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.5520501625
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.5518949393 18448328 14970324 16391804 16331619 15289873 15148649 17594712 18509181 16282729 20501625 17695437 17454858 17016601 16303861 18288408 17094418 18802399 16524972 17255274 18383874 17401013
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0814669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 4.2212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 9.5410525206
MESH:D019465 Craniofacial Abnormalities sodium arsenate 9.5410525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 9.5410048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 9.549224671 17551590 14991402 10589399 9142499 16925845 8800419 9664655 9211117 9125849
MESH:D019465 Craniofacial Abnormalities Valproic Acid 9.5417688650 8888407 16575769
MESH:D019465 Craniofacial Abnormalities Vitamin E 9.5419769572
MESH:D007644 Darier Disease Fluorouracil 4.8416733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.1315213294
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4418249437
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6717107852
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 12.1218071297 11529661 10915739 15619225 11287661 11421492 19085960 16393943 16109766 12392966 19416960 12594235 12705907 11834606 17906064 16485898 15968718 11743745 18713872 10663392 11461765 19420014 16177239 14550746 16781746 2444490 19739265 12958197 12153990 10774834 14725611 17522070 17562736 14986274 12540782 19164858 19370779 11739529 16227642 19923254 16081117
MESH:D056486 Drug-Induced Liver Injury Selenium 12.1215131321
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 12.1218186108
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.1220420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 12.121733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1619426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7811462148
MESH:D050171 Dyslipidemias Dietary Fats 3.4718367378
MESH:D004421 Dystonia Valproic Acid 4.081851702
MESH:C538011 Eales disease Vitamin E 4.779068938
MESH:D004487 Edema pirinixic acid 6.6312083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.6311000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 12.1618230668 16714409 15322242
MESH:D004489 Edema, Cardiac Tretinoin 12.1618230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.2212538720
MESH:D016889 Endometrial Neoplasms Tretinoin 3.1216569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.0510568697 9294722
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.193659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 3.9816628512 3922381
MESH:D004827 Epilepsy Valproic Acid 2.9520417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.617562514 6254150 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.347750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.113659116
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.6212903497
MESH:D004938 Esophageal Neoplasms Fluorouracil 4.6217638652 16481741 16337965 15173087 16785472
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.9011564622
MESH:D005124 Eye Abnormalities Tretinoin 8.9016938888 9664655
MESH:D005234 Fatty Liver arsenic trioxide 31.1715073043
MESH:D005234 Fatty Liver Cyclosporine 31.1719224547
MESH:D005234 Fatty Liver Dietary Fats 31.1717967931 19004024 19551842 18296743
MESH:D005234 Fatty Liver Ethinyl Estradiol 31.1715345470
MESH:D005234 Fatty Liver pirinixic acid 31.1719236843 20131406
MESH:D005234 Fatty Liver Valproic Acid 31.1714986274 19224547
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5011858732
MESH:D005315 Fetal Diseases Valproic Acid 4.9516575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.178888407 18558336
MESH:D005355 Fibrosis Cyclosporine 21.5212168785 12639820
MESH:D005355 Fibrosis Dietary Fats 21.5218296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 21.5220067830
MESH:D005355 Fibrosis Tretinoin 21.5217994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.3016904648
MESH:D005756 Gastritis Acetaminophen 3.7416983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.278708960
MESH:D005909 Glioblastoma Tretinoin 3.0217312396
MESH:D005910 Glioma Fluorouracil 2.8816145905
MESH:D018149 Glucose Intolerance sodium arsenate 5.1119446573
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6610696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 7.8515102660 15162350 18337622
MESH:D006258 Head and Neck Neoplasms Tretinoin 7.8516096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.2216084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.2210048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 11.2214991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin E 11.2216080930
MESH:D006333 Heart Failure pirinixic acid 7.0120558911
MESH:D006333 Heart Failure Selenium 7.0117162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.4715720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3611000095
MESH:D006529 Hepatomegaly pirinixic acid 8.4016221962 19772884 19176532 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.4012621046 16120746 15340226
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7116863852 16490937
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.8117440010
MESH:D019584 Hot Flashes Vitamin E 4.0314716179
MESH:D006849 Hydrocephalus Valproic Acid 4.9217688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.1115340226 16354765 8697196 16959395 18606429
MESH:D006930 Hyperalgesia Acetaminophen 7.7016870215
MESH:D006930 Hyperalgesia Tretinoin 7.7016870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.6221332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.6116778211
MESH:D006943 Hyperglycemia pirinixic acid 3.2120558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.6521332399
MESH:D006973 Hypertension Cyclosporine 4.9810903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.9818670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8516945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5017937319
MESH:D007249 Inflammation Dietary Fats 4.9620412841
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.9612878042 12200463
MESH:D007251 Influenza, Human Selenium 11.1716624496
MESH:D007251 Influenza, Human Vitamin E 11.1716624496
MESH:D007333 Insulin Resistance Dietary Fats 7.3111836018 18457598
MESH:D007333 Insulin Resistance pirinixic acid 7.3116306350
MESH:D007410 Intestinal Diseases Tretinoin 3.8117994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 10.0316580747
MESH:D007569 Jaw Abnormalities Tretinoin 10.0317551590 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.5015604871
MESH:D007674 Kidney Diseases Acetaminophen 10.1012587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 10.1018776723 8314463 10903974
MESH:D007674 Kidney Diseases Vitamin E 10.1012488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.9116518626
MESH:D007680 Kidney Neoplasms Cyclosporine 7.4712371664
MESH:D007680 Kidney Neoplasms Fluorouracil 7.4716985049
MESH:D007938 Leukemia arsenic trioxide 6.3815070760
MESH:D007938 Leukemia Tretinoin 6.3817143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.8217077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.3616972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.4514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.5719077051
MESH:D007951 Leukemia, Myeloid Tretinoin 9.5716482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 6.1520471514 17050201 19850784 16968895 16467208
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 6.1517596541 19850784 16294345
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 6.1517596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.6912712474 12018890 19075265 12679006 15213294 9834237 15622746 16112521 17649720 16330433 16891316 15336539 16823087 17869043 19035177 11161223 16966277 17107899 16331271 11468182 19225113 19642359 15748426 17712046 17217047
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.6916823087 16140955 16935935 16766008 17107899 15748426 17649720 16331271 16788101 17339181 17361223 17712046 17301526 19029980 16891316 17368321 19075265 12679006 19035177 17506722 17294898 17217047 19642359 19225113 9834237
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.3916882451
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.339224671
MESH:D008103 Liver Cirrhosis Dietary Fats 2.8918296743
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.9615474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.9612878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 4.9618397230 16248980
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.9616169303
MESH:D008107 Liver Diseases Acetaminophen 1.6319014921 16611625 11587558 12969438 19460945 16610002 12587719 19784758
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2617185352 16871587
MESH:D008113 Liver Neoplasms arsenic trioxide 10.7714682389
MESH:D008113 Liver Neoplasms Fluorouracil 10.7717045692 16603448 15113037 18383874
MESH:D008113 Liver Neoplasms pirinixic acid 10.7715890375 16377806 20007298
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 10.7716984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 5.8620377131
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 5.8612151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3715213294
MESH:D008171 Lung Diseases Vitamin E 3.1916863852
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.3217228818
MESH:D008175 Lung Neoplasms arsenic trioxide 4.8819825857 11798837
MESH:D008175 Lung Neoplasms Fluorouracil 4.8815246190
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.8811884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 4.8811062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.8415086387
MESH:D008325 Mammary Neoplasms, Experimental Selenium 2.7815318939
MESH:D008527 Medulloblastoma Tretinoin 2.7917453147
MESH:D008545 Melanoma Tretinoin 1.9516752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.6119513568
MESH:D008591 Meningomyelocele Tretinoin 4.4716940565
MESH:D008654 Mesothelioma Selenium 2.8015107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.8516801185
MESH:D008881 Migraine Disorders Valproic Acid 3.2118803445 18765137
MESH:D009062 Mouth Neoplasms Fluorouracil 3.6518986760 16757204
MESH:D009101 Multiple Myeloma arsenic trioxide 3.1211468182 19417148 14977855 15949261 19549372
MESH:D009135 Muscular Diseases pirinixic acid 3.5516239165
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 10.7818186108
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 10.788888407
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.7318349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 12.4016105982 16882451
MESH:D009190 Myelodysplastic Syndromes Tretinoin 12.4017596541
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 12.4017596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.1519151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0412213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.9716411023
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.0016624393
MESH:D009369 Neoplasms Fluorouracil 8.3318600527 18239605 16928823
MESH:D009369 Neoplasms pirinixic acid 8.3317405874
MESH:D009369 Neoplasms Tretinoin 8.3316594593 16946489
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.5017954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.3119348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.6314600291
MESH:D009421 Nervous System Malformations Tretinoin 9.639125849
MESH:D009436 Neural Tube Defects arsenic trioxide 17.5310525206
MESH:D009436 Neural Tube Defects sodium arsenate 17.5311749123 10525206 18186108 19446573
MESH:D009436 Neural Tube Defects Tretinoin 17.539142499
MESH:D009436 Neural Tube Defects Valproic Acid 17.5316359493 8888407
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.8918514411
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.4516436463
MESH:D009765 Obesity Dietary Fats 4.4520132043 21332399 11836018 17217161 18457598 20518802 18674790 16723640 19632207
MESH:D009765 Obesity pirinixic acid 4.4520558911
MESH:D010051 Ovarian Neoplasms arsenic trioxide 4.9016624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms Tretinoin 4.9016936753
MESH:D010146 Pain Acetaminophen 6.6616870215
MESH:D010146 Pain Tretinoin 6.6616870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.7015580305
MESH:D010190 Pancreatic Neoplasms Fluorouracil 8.7015113037 16929163 19003803 16500647
MESH:D010190 Pancreatic Neoplasms Tretinoin 8.7015976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7211578682
MESH:D010235 Paraganglioma arsenic trioxide 4.1919927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3112520081
MESH:D010954 Plasmacytoma Selenium 4.9515087411
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5918163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.2512371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.6311118676 11399792 11896295 11222880
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 9.6320603192
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.6119131511
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.6119082440 18626508
MESH:D011471 Prostatic Neoplasms Vitamin E 2.6115084515
MESH:D011507 Proteinuria Tretinoin 3.6416636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.3615861022 16919318
MESH:D019310 Pseudolymphoma Valproic Acid 4.6012752131 11422049
MESH:D011565 Psoriasis Cyclosporine 2.2416882103
MESH:D011625 Pterygium Tretinoin 4.8416723453
MESH:D012004 Rectal Neoplasms Fluorouracil 4.0418286688 16160472 18722050 15538739
MESH:D015427 Reperfusion Injury pirinixic acid 2.4019058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8718990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 10.9716283617 16116481
MESH:D012208 Rhabdomyosarcoma Valproic Acid 10.9719155313
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.0016646077
MESH:D012559 Schizophrenia Valproic Acid 2.0719110320 15737665
MESH:D012640 Seizures Valproic Acid 2.7517978042 3137016 1511512 14763951 11738929 11044598 16876388 15475178
MESH:D012871 Skin Diseases Vitamin E 2.4518709164
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.6016192470
MESH:D012878 Skin Neoplasms Tretinoin 5.6016467112
MESH:D013088 Spermatocele Ethinyl Estradiol 4.0016709447
MESH:D016135 Spinal Dysraphism Valproic Acid 3.8019490988
MESH:D013226 Status Epilepticus Valproic Acid 4.6012833885
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.4117007042
MESH:D013274 Stomach Neoplasms Fluorouracil 3.4117172411 17522103 15786421 17498489 18396642 16424979 16951190 19015929 18567086 19084572
MESH:D013274 Stomach Neoplasms Tretinoin 3.4117261132
MESH:D020521 Stroke Vitamin E 3.5416517955
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9612697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 7.2819014326
MESH:D013964 Thyroid Neoplasms Tretinoin 7.2816026305 17045167
MESH:D014062 Tongue Neoplasms Fluorouracil 9.9216280240
MESH:D014062 Tongue Neoplasms Tretinoin 9.9216051514
MESH:D016171 Torsades de Pointes arsenic trioxide 4.0115213294
MESH:D014178 Translocation, Genetic Valproic Acid 5.3017262798
MESH:D014376 Tuberculosis Tretinoin 3.2416040207
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.573119515
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 2.4911780464 20435036 12973940 12845720
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.688888407
MESH:D014581 Urticaria Acetaminophen 3.0110982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 9.5416803524
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 9.5416129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3314692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.6716752155
MESH:D014605 Uveitis Cyclosporine 4.051336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6612125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5714671159 15869587
MESH:D014820 Vitiligo Tretinoin 4.0916761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3115886252
MESH:D015430 Weight Gain Dietary Fats 3.7616723640
MESH:D009396 Wilms Tumor Tretinoin 3.9916287080
MESH:D014985 Xerophthalmia Cyclosporine 4.5017120751
Pathway ID Pathway Name
KEGG:04141 Protein processing in endoplasmic reticulum
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA34863
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved