AutismKB 2.0

Annotation Detail for RXRA


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Basic Information Top
Gene Symbol:RXRA ( FLJ00280,FLJ00318,FLJ16020,FLJ16733,MGC102720,NR2B1 )
Gene Full Name: retinoid X receptor, alpha
Band: 9q34.2
Quick LinksEntrez ID:6256; OMIM: 180245; Uniprot ID:RXRA_HUMAN; ENSEMBL ID: ENSG00000186350; HGNC ID: 10477
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04920Adipocytokine signaling pathway
hsa05160Hepatitis C
hsa03320PPAR signaling pathway
hsa05216Thyroid cancer
hsa05223Non-small cell lung cancer
hsa05222Small cell lung cancer
hsa05200Pathways in cancer
Pathway IDPathway Name
Gene Expression
Metabolism of lipids and lipoproteins
Pathway IDPathway Name
200142Retinoic acid receptors-mediated signaling
200112RXR and RAR heterodimerization with other nuclear receptor
No data
Pathway IDPathway Name
500817Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1934Cancer
2220Dermatitis
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C097949 1,25-dihydroxyvitamin D 1,25-dihydroxyvitamin D promotes the reaction [VDR protein binds to RXRA protein]affects binding|increases reaction 15837528
C097949 1,25-dihydroxyvitamin D 1,25-dihydroxyvitamin D results in decreased expression of RXRA mRNAdecreases expression 15331595
C031338 13-cis-retinal 13-cis-retinal promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]affects binding|increases expression|increases reaction 16632523
C028474 1,4-bis(2-(3,5-dichloropyridyloxy))benzene [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with alitretinoin] promotes the reaction [[NR1I3 protein binds to RXRA protein] which binds to NCOA1 protein]affects binding|affects cotreatment|increases reaction 17223708
C028474 1,4-bis(2-(3,5-dichloropyridyloxy))benzene 1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [[NR1I3 protein binds to RXRA protein] which binds to NCOA1 protein]affects binding|increases reaction 17223708
C097240 15-deoxy-delta(12,14)-prostaglandin J2 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of RXRAincreases expression 15254749
C483845 2-(2-(4-phenoxy-2-propylphenoxy)ethyl)indole-5-acetic acid RXRA protein results in increased susceptibility to 2-(2-(4-phenoxy-2-propylphenoxy)ethyl)indole-5-acetic acidincreases response to substance 17259670
C022776 2-bromopalmitate 2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein]affects binding|increases activity 15997096
C054189 3,5-di-tert-butylchalcone 4'-carboxylic acid 3,5-di-tert-butylchalcone 4'-carboxylic acid results in increased expression of RXRA mRNAincreases expression 7556191
C034534 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid [Vitamin K 2 co-treated with 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid] results in decreased phosphorylation of RXRA proteinaffects cotreatment|decreases phosphorylation 17270033
C034534 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid results in decreased phosphorylation of RXRA proteindecreases phosphorylation 21071580
C038864 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in decreased expression of RXRA mRNAdecreases expression 15583048
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of RXRA mRNAincreases expression 18648102
C041594 4-nonylphenol 4-nonylphenol results in decreased expression of RXRA mRNAdecreases expression 16013040
C031390 9-cis-retinal 9-cis-retinal promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]affects binding|increases expression|increases reaction 16632523
C037112 9-deoxy-delta-9-prostaglandin D2 [9-deoxy-delta-9-prostaglandin D2 co-treated with alitretinoin] promotes the reaction [[PPARG protein binds to RXRA protein] which binds to GSTA2 promoter]affects binding|affects cotreatment|increases reaction 15150131
D000082 Acetaminophen RXRA protein promotes the reaction [Acetaminophen results in increased expression of CYP1A2 mRNA]increases expression|increases reaction 14978233
D000082 Acetaminophen RXRA protein promotes the reaction [Acetaminophen results in increased expression of CYP3A11 mRNA]increases expression|increases reaction 14978233
D000082 Acetaminophen RXRA protein results in increased susceptibility to Acetaminophenincreases response to substance 14978233
C430898 AGN 194204 AGN 194204 binds to and results in increased activity of RXRA proteinaffects binding|increases activity 16178010
C430898 AGN 194204 RXRA protein results in increased susceptibility to AGN 194204increases response to substance 15318936
C103303 alitretinoin alitretinoin binds to and results in increased activity of RXRA proteinaffects binding|increases activity 7565671
C103303 alitretinoin [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with alitretinoin] promotes the reaction [[NR1I3 protein binds to RXRA protein] which binds to NCOA1 protein]affects binding|affects cotreatment|increases reaction 17223708
C103303 alitretinoin alitretinoin affects the localization of RXRA proteinaffects localization 17170071
C103303 alitretinoin alitretinoin analog binds to and results in increased activity of RXRA proteinaffects binding|increases activity 16946489
C103303 alitretinoin alitretinoin binds to and affects the activity of RXRA proteinaffects activity|affects binding 15941851
C103303 alitretinoin alitretinoin binds to and results in increased activity of RXRA proteinaffects binding|increases activity 16946489
15866424
C103303 alitretinoin [alitretinoin binds to and results in increased activity of RXRA protein] which results in increased expression of CYP19A1 proteinaffects binding|increases activity|increases expression 15941851
C103303 alitretinoin [alitretinoin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the localization of RXRA proteinaffects cotreatment|affects localization 17170071
C103303 alitretinoin [alitretinoin co-treated with Calcitriol] results in increased stability of [RXRA protein binds to VDR protein]affects binding|affects cotreatment|increases stability 16204233
C103303 alitretinoin [alitretinoin co-treated with RXRA protein] results in increased expression of PSG5 mRNAaffects cotreatment|increases expression 17475324
C103303 alitretinoin alitretinoin inhibits the reaction [triphenyltin hydroxide binds to RXRA protein]affects binding|decreases reaction 15941851
C103303 alitretinoin alitretinoin promotes the reaction [[NR1I3 protein binds to RXRA protein] which binds to NCOA1 protein]affects binding|increases reaction 17223708
C103303 alitretinoin alitretinoin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]affects binding|increases expression|increases reaction 16632523
C103303 alitretinoin alitretinoin results in decreased expression of RXRA proteindecreases expression 15375546
C103303 alitretinoin [alitretinoin results in increased activity of RXRA protein] which binds to PSG5 promoteraffects binding|increases activity 17475324
C103303 alitretinoin alitretinoin results in increased degradation of RXRA proteinincreases degradation 17170071
C103303 alitretinoin alitretinoin results in increased expression of RXRA mRNAincreases expression 11139446
C103303 alitretinoin alitretinoin results in increased ubiquitination of RXRA proteinincreases ubiquitination 17170071
C103303 alitretinoin benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [alitretinoin results in increased degradation of RXRA protein]decreases reaction|increases degradation 17170071
C103303 alitretinoin [pirinixic acid co-treated with alitretinoin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNAaffects cotreatment|decreases expression 16292757
C103303 alitretinoin RXRA protein binds to alitretinoinaffects binding 16460010
C103303 alitretinoin tributyltin inhibits the reaction [alitretinoin binds to RXRA protein]affects binding|decreases reaction 15941851
C103303 alitretinoin triphenyltin chloride inhibits the reaction [alitretinoin binds to RXRA protein]affects binding|decreases reaction 15941851
C103303 alitretinoin triphenyltin hydroxide inhibits the reaction [alitretinoin binds to RXRA protein]affects binding|decreases reaction 15941851
C103303 alitretinoin alitretinoin binds to and results in increased activity of RXRA proteinaffects binding|increases activity 17084873
C103303 alitretinoin alitretinoin binds to [RXRA protein binds to RARB protein]affects binding 15159591
C103303 alitretinoin alitretinoin inhibits the reaction [TGIF1 protein binds to RXRA protein]affects binding|decreases reaction 16428452
C103303 alitretinoin alitretinoin inhibits the reaction [TGIF1 protein results in increased activity of RXRA protein]decreases reaction|increases activity 16428452
C103303 alitretinoin alitretinoin results in increased activity of [RXRA protein binds to RXRA protein]affects binding|increases activity 15997096
C103303 alitretinoin alitretinoin results in increased localization of RXRA proteinincreases localization 16204233
C103303 alitretinoin ethyl(E,E,E)-7-(2-n-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-3-yl)-6-fluorp-3-methylocta-2,4,6-trienoate inhibits the reaction [alitretinoin results in increased activity of [RXRA protein binds to RXRA protein]]affects binding|decreases reaction|increases activity 15997096
C103303 alitretinoin RXRA protein promotes the reaction [alitretinoin results in increased expression of PPARGC1A mRNA]increases expression|increases reaction 16513826
C103303 alitretinoin [9-deoxy-delta-9-prostaglandin D2 co-treated with alitretinoin] promotes the reaction [[PPARG protein binds to RXRA protein] which binds to GSTA2 promoter]affects binding|affects cotreatment|increases reaction 15150131
C103303 alitretinoin alitretinoin results in increased expression of RXRA proteinincreases expression 16043492
C103303 alitretinoin alitretinoin results in increased activity of RXRA proteinincreases activity 15178767
C103303 alitretinoin alitretinoin binds to and results in increased activity of RXRA proteinaffects binding|increases activity 16037943
C103303 alitretinoin alitretinoin binds to [PPARG protein binds to RXRA protein]affects binding 10882139
C103303 alitretinoin alitretinoin binds to RXRA proteinaffects binding 17387344
D024502 alpha-Tocopherol [Tretinoin co-treated with alpha-Tocopherol co-treated with Okadaic Acid] results in decreased phosphorylation of RXRA proteinaffects cotreatment|decreases phosphorylation 15225641
D024502 alpha-Tocopherol [Tretinoin co-treated with alpha-Tocopherol] results in decreased phosphorylation of RXRA proteinaffects cotreatment|decreases phosphorylation 15225641
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RXRA mRNAaffects expression 16483693
D000841 Anisomycin Anisomycin results in increased phosphorylation of RXRA proteinincreases phosphorylation 16038797
D000841 Anisomycin anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Anisomycin results in increased phosphorylation of RXRA protein]decreases reaction|increases phosphorylation 16038797
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Anisomycin results in increased phosphorylation of RXRA protein]decreases reaction|increases phosphorylation 16038797
D016590 Aphidicolin Aphidicolin results in increased expression of RXRA mRNAincreases expression 14738865
C006632 arsenic trioxide arsenic trioxide results in increased expression of RXRA mRNAincreases expression 19769630
C006632 arsenic trioxide arsenic trioxide inhibits the reaction [RXRA protein binds to PPARG protein]affects binding|decreases reaction 15916724
C006632 arsenic trioxide arsenic trioxide results in decreased expression of RXRA proteindecreases expression 15916724
C006632 arsenic trioxide arsenic trioxide results in increased phosphorylation of RXRA proteinincreases phosphorylation 15688020
D017638 Asbestos, Crocidolite Asbestos, Crocidolite affects the expression of RXRA mRNAaffects expression 17331233
D001554 Benzene Benzene results in increased expression of RXRA mRNAincreases expression 15878777
D001564 Benzo(a)pyrene Benzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [RXRA protein binds to CYP24A1 promoter]]affects binding|decreases reaction|increases reaction 19244278
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of RXRA mRNAdecreases expression 20064835
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RXRA mRNAdecreases expression 19150397
C072553 benzyloxycarbonylleucyl-leucyl-leucine aldehyde [alitretinoin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the localization of RXRA proteinaffects cotreatment|affects localization 17170071
C072553 benzyloxycarbonylleucyl-leucyl-leucine aldehyde benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [alitretinoin results in increased degradation of RXRA protein]decreases reaction|increases degradation 17170071
C072553 benzyloxycarbonylleucyl-leucyl-leucine aldehyde benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased degradation of RXRA protein]decreases degradation|decreases reaction 12970875
C072553 benzyloxycarbonylleucyl-leucyl-leucine aldehyde benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of and results in increased expression of RXRA proteinincreases expression|increases stability 15707588
D019207 beta Carotene beta Carotene promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]affects binding|increases expression|increases reaction 16632523
D001647 Bile Acids and Salts RXRA protein promotes the reaction [pirinixic acid results in increased abundance of Bile Acids and Salts]increases abundance|increases reaction 19176532
C070515 bisindolylmaleimide I [Tretinoin co-treated with bisindolylmaleimide I] results in decreased phosphorylation of RXRA proteinaffects cotreatment|decreases phosphorylation 15225641
C006780 bisphenol A bisphenol A results in decreased expression of RXRA mRNAdecreases expression 14967906
C006780 bisphenol A bisphenol A results in increased expression of RXRA mRNAincreases expression 15738621
14967906
D020122 tert-Butylhydroperoxide RXRA protein results in decreased susceptibility to tert-Butylhydroperoxidedecreases response to substance 14978233
C058819 calphostin C [Tretinoin co-treated with calphostin C] results in decreased phosphorylation of RXRA proteinaffects cotreatment|decreases phosphorylation 15225641
D002211 Capsaicin Capsaicin results in decreased expression of RXRA mRNAdecreases expression 18769453
C505748 CD4528 CD4528 promotes the reaction [VDR protein binds to RXRA protein]affects binding|increases reaction 15860548
D002994 Clofibrate Clofibrate results in increased stability of RXRA proteinincreases stability 12753917
D002995 Clofibric Acid Clofibric Acid results in increased expression of RXRA proteinincreases expression 15670589
D003907 Dexamethasone Dexamethasone results in increased expression of RXRA mRNAincreases expression 19022236
D003907 Dexamethasone Dexamethasone results in increased expression of RXRA proteinincreases expression 15965953
C438269 diazepinylbenzoic acid diazepinylbenzoic acid binds to and results in decreased activity of RXRA proteinaffects binding|decreases activity 19095448
D004041 Dietary Fats Dietary Fats affects the expression of RXRA mRNAaffects expression 16079505
D002117 Calcitriol [alitretinoin co-treated with Calcitriol] results in increased stability of [RXRA protein binds to VDR protein]affects binding|affects cotreatment|increases stability 16204233
D002117 Calcitriol Benzo(a)pyrene inhibits the reaction [Calcitriol promotes the reaction [RXRA protein binds to CYP24A1 promoter]]affects binding|decreases reaction|increases reaction 19244278
D002117 Calcitriol Calcitriol promotes the reaction [RXRA protein binds to CYP24A1 promoter]affects binding|increases reaction 19244278
D002117 Calcitriol Calcitriol promotes the reaction [[VDR protein binds to RXRA protein] which binds to CYP24A1 promoter]affects binding|increases reaction 15919092
D002117 Calcitriol Calcitriol affects the expression of RXRA proteinaffects expression 16368784
D002117 Calcitriol Calcitriol affects the localization of RXRA proteinaffects localization 15647825
D002117 Calcitriol Calcitriol promotes the reaction [RXRA protein binds to CYP24A1 promoter]affects binding|increases reaction 15647825
D002117 Calcitriol Calcitriol promotes the reaction [RXRA protein binds to SPP1 promoter]affects binding|increases reaction 15647825
D002117 Calcitriol Calcitriol promotes the reaction [[VDR protein binds to RXRA protein] which binds to CYP24A1 promoter]affects binding|increases reaction 15992766
D002117 Calcitriol Calcitriol promotes the reaction [[VDR protein binds to RXRA protein] which binds to CYP3A4 promoter]affects binding|increases reaction 15992766
C472511 dimethylarsinous acid dimethylarsinous acid results in increased expression of RXRA mRNAincreases expression 19084030
D004121 Dimethyl Sulfoxide Dimethyl Sulfoxide results in increased expression of RXRA mRNAincreases expression 9751115
D004121 Dimethyl Sulfoxide Dimethyl Sulfoxide results in increased expression of RXRA proteinincreases expression 9751115
D004121 Dimethyl Sulfoxide RXRA protein affects the susceptibility to Dimethyl Sulfoxideaffects response to substance 9751115
D004281 Docosahexaenoic Acids Docosahexaenoic Acids binds to and results in increased activity of RXRA proteinaffects binding|increases activity 12844485
D004281 Docosahexaenoic Acids Docosahexaenoic Acids binds to and results in increased activity of RXRA proteinaffects binding|increases activity 12844485
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of RXRA mRNAdecreases expression 16872691
C504648 ethyl(E,E,E)-7-(2-n-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-3-yl)-6-fluorp-3-methylocta-2,4,6-trienoate ethyl(E,E,E)-7-(2-n-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-3-yl)-6-fluorp-3-methylocta-2,4,6-trienoate inhibits the reaction [alitretinoin results in increased activity of [RXRA protein binds to RXRA protein]]affects binding|decreases reaction|increases activity 15997096
C504648 ethyl(E,E,E)-7-(2-n-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-3-yl)-6-fluorp-3-methylocta-2,4,6-trienoate ethyl(E,E,E)-7-(2-n-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-3-yl)-6-fluorp-3-methylocta-2,4,6-trienoate results in increased activity of [RXRA protein binds to PPARA protein]affects binding|increases activity 15997096
C504648 ethyl(E,E,E)-7-(2-n-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-3-yl)-6-fluorp-3-methylocta-2,4,6-trienoate ethyl(E,E,E)-7-(2-n-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-3-yl)-6-fluorp-3-methylocta-2,4,6-trienoate results in increased activity of [RXRA protein binds to PPARD protein]affects binding|increases activity 15997096
C504648 ethyl(E,E,E)-7-(2-n-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-3-yl)-6-fluorp-3-methylocta-2,4,6-trienoate ethyl(E,E,E)-7-(2-n-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-3-yl)-6-fluorp-3-methylocta-2,4,6-trienoate results in increased activity of [RXRA protein binds to PPARG protein]affects binding|increases activity 15997096
C504648 ethyl(E,E,E)-7-(2-n-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-3-yl)-6-fluorp-3-methylocta-2,4,6-trienoate ethyl(E,E,E)-7-(2-n-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-3-yl)-6-fluorp-3-methylocta-2,4,6-trienoate results in increased activity of [RXRA protein binds to RXRA protein]affects binding|increases activity 15997096
D017308 Etodolac Etodolac binds to and results in decreased activity of RXRA proteinaffects binding|decreases activity 15699354
D017308 Etodolac Etodolac results in increased degradation of RXRA proteinincreases degradation 15699354
C422415 farglitazar farglitazar binds to [PPARG protein binds to RXRA protein]affects binding 10882139
D015525 Fatty Acids, Omega-3 Fatty Acids, Omega-3 results in increased expression of RXRA mRNAincreases expression 12844485
D005231 Fatty Acids, Unsaturated Fatty Acids, Unsaturated results in increased expression of RXRA mRNAincreases expression 16571146
D005978 Glutathione GCLC protein affects the reaction [RXRA protein affects the abundance of Glutathione]affects abundance|affects reaction 14978233
D005978 Glutathione RXRA protein affects the abundance of Glutathioneaffects abundance 14978233
D006118 Griseofulvin Griseofulvin results in decreased expression of RXRA mRNAdecreases expression 9548566
C120099 GW 1929 GW 1929 results in increased activity of [PPARG protein binds to RXRA protein]affects binding|increases activity 20008677
C120099 GW 1929 ZNF366 protein promotes the reaction [GW 1929 results in increased activity of [PPARG protein binds to RXRA protein]]affects binding|increases activity|increases reaction 20008677
D017313 Fenretinide Fenretinide promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]affects binding|increases expression|increases reaction 16632523
D017313 Fenretinide Fenretinide results in decreased expression of RXRA proteindecreases expression 15375546
D017313 Fenretinide Fenretinide results in increased expression of RXRA mRNAincreases expression 16570282
D007213 Indomethacin [L 663536 co-treated with Indomethacin] results in increased expression of RXRA mRNAaffects cotreatment|increases expression 15899809
C060893 L 663536 [L 663536 co-treated with Indomethacin] results in increased expression of RXRA mRNAaffects cotreatment|increases expression 15899809
C060893 L 663536 L 663536 results in increased expression of RXRA mRNAincreases expression 15899809
C095104 LG 100268 LG 100268 binds to and results in increased activity of RXRA proteinaffects binding|increases activity 12519787
C095104 LG 100268 [LG 100268 binds to and results in increased activity of RXRA protein] which results in increased expression of CYP19A1 proteinaffects binding|increases activity|increases expression 15941851
C095104 LG 100268 LG 100268 inhibits the reaction [[NR1H4 protein binds to RXRA protein] which binds to ABCB11 promoter]affects binding|decreases reaction 12519787
C095104 LG 100268 LG 100268 results in increased activity of RXRA proteinincreases activity 15544927
C095104 LG 100268 LG 100268 results in increased activity of RXRA protein alternative formincreases activity 15544927
C423914 LG 268 LG 268 results in increased activity of RXRA proteinincreases activity 15178767
C423914 LG 268 LG 268 promotes the reaction [NCOA3 protein binds to [RXRA protein binds to RXRA protein]]affects binding|increases reaction 15310754
D001556 Lindane Lindane affects the expression of RXRA mRNAaffects expression 17785943
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased activity of RXRA proteindecreases activity 12388159
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of RXRA mRNAdecreases expression 16847310
12388159
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of RXRA proteindecreases expression 16002565
12388159
16847310
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased localization of RXRA proteindecreases localization 15312234
D008095 Lithocholic Acid Lithocholic Acid promotes the reaction [VDR protein binds to RXRA protein]affects binding|increases reaction 15824121
D008095 Lithocholic Acid Lithocholic Acid promotes the reaction [[VDR protein binds to RXRA protein] which binds to CYP24A1 promoter]affects binding|increases reaction 15992766
D008095 Lithocholic Acid Lithocholic Acid promotes the reaction [[VDR protein binds to RXRA protein] which binds to CYP3A4 promoter]affects binding|increases reaction 15992766
D008095 Lithocholic Acid Lithocholic Acid promotes the reaction [[VDR protein binds to RXRA protein] which results in increased expression of ABCC3]affects binding|increases expression|increases reaction 15824121
D008095 Lithocholic Acid Lithocholic Acid promotes the reaction [[VDR protein binds to RXRA protein] which results in increased expression of CYP3A11]affects binding|increases expression|increases reaction 15824121
D008095 Lithocholic Acid Lithocholic Acid promotes the reaction [[VDR protein binds to RXRA protein] which results in increased expression of SULT2A2]affects binding|increases expression|increases reaction 15824121
D008701 Methapyrilene Methapyrilene results in decreased expression of RXRA mRNAdecreases expression 17450226
C423917 MG 262 MG 262 results in increased stability of and results in increased expression of RXRA proteinincreases expression|increases stability 15707588
C007350 nitrofen nitrofen results in increased expression of RXRA mRNAincreases expression 17270546
D019319 Okadaic Acid [Tretinoin co-treated with alpha-Tocopherol co-treated with Okadaic Acid] results in decreased phosphorylation of RXRA proteinaffects cotreatment|decreases phosphorylation 15225641
C484027 oligofectamine oligofectamine results in decreased expression of RXRA mRNAdecreases expression 14668052
D009963 Orotic Acid [Sucrose co-treated with Orotic Acid] results in decreased expression of RXRA proteinaffects cotreatment|decreases expression 15670589
D010269 Paraquat Paraquat results in decreased expression of RXRA mRNAdecreases expression 16797015
C023036 perfluorooctanoic acid RXRA protein results in increased susceptibility to perfluorooctanoic acidincreases response to substance 17259670
D010634 Phenobarbital Phenobarbital affects the expression of RXRA mRNAaffects expression 16510358
C006253 pirinixic acid [pirinixic acid co-treated with alitretinoin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNAaffects cotreatment|decreases expression 16292757
C006253 pirinixic acid pirinixic acid promotes the reaction [[PPARA protein co-treated with RXRA protein] results in increased expression of IL1RN mRNA]affects cotreatment|increases expression|increases reaction 17321000
C006253 pirinixic acid pirinixic acid results in increased activity of [RXRA protein binds to PPARA protein]affects binding|increases activity 15997096
C006253 pirinixic acid RXRA protein affects the reaction [pirinixic acid results in increased expression of ABCC3 mRNA]affects reaction|increases expression 19176532
C006253 pirinixic acid RXRA protein inhibits the reaction [pirinixic acid results in decreased expression of SLCO1A1 mRNA]decreases expression|decreases reaction 19176532
C006253 pirinixic acid RXRA protein inhibits the reaction [pirinixic acid results in increased expression of CYP3A11 mRNA]decreases reaction|increases expression 19176532
C006253 pirinixic acid RXRA protein inhibits the reaction [pirinixic acid results in increased expression of CYP3A11 protein]decreases reaction|increases expression 19176532
C006253 pirinixic acid RXRA protein inhibits the reaction [pirinixic acid results in increased expression of NR0B2 mRNA]decreases reaction|increases expression 19176532
C006253 pirinixic acid RXRA protein promotes the reaction [pirinixic acid results in decreased expression of WEE1 protein]decreases expression|increases reaction 19176532
C006253 pirinixic acid RXRA protein promotes the reaction [pirinixic acid results in increased abundance of Bile Acids and Salts]increases abundance|increases reaction 19176532
C006253 pirinixic acid RXRA protein promotes the reaction [pirinixic acid results in increased expression of ACOX1 mRNA]increases expression|increases reaction 19176532
C006253 pirinixic acid RXRA protein promotes the reaction [pirinixic acid results in increased expression of ACOX1 protein]increases expression|increases reaction 19176532
C006253 pirinixic acid RXRA protein promotes the reaction [pirinixic acid results in increased expression of ALPL protein]increases expression|increases reaction 19176532
C006253 pirinixic acid RXRA protein promotes the reaction [pirinixic acid results in increased expression of CCNA2 mRNA]increases expression|increases reaction 19176532
C006253 pirinixic acid RXRA protein promotes the reaction [pirinixic acid results in increased expression of CCNB1 mRNA]increases expression|increases reaction 19176532
C006253 pirinixic acid RXRA protein promotes the reaction [pirinixic acid results in increased expression of CCND1 mRNA]increases expression|increases reaction 19176532
C006253 pirinixic acid RXRA protein promotes the reaction [pirinixic acid results in increased expression of CCND1 protein]increases expression|increases reaction 19176532
C006253 pirinixic acid RXRA protein promotes the reaction [pirinixic acid results in increased expression of CCND3 mRNA]increases expression|increases reaction 19176532
C006253 pirinixic acid RXRA protein promotes the reaction [pirinixic acid results in increased expression of CCND3 protein]increases expression|increases reaction 19176532
C006253 pirinixic acid RXRA protein promotes the reaction [pirinixic acid results in increased expression of CDK1 mRNA]increases expression|increases reaction 19176532
C006253 pirinixic acid RXRA protein promotes the reaction [pirinixic acid results in increased expression of CDK1 protein]increases expression|increases reaction 19176532
C006253 pirinixic acid RXRA protein promotes the reaction [pirinixic acid results in increased expression of IL1B mRNA]increases expression|increases reaction 19176532
C006253 pirinixic acid RXRA protein promotes the reaction [pirinixic acid results in increased expression of PCNA protein]increases expression|increases reaction 19176532
C006253 pirinixic acid RXRA protein results in increased susceptibility to pirinixic acidincreases response to substance 19176532
C443641 poly(propyleneimine) poly(propyleneimine) analog results in increased expression of RXRA mRNAincreases expression 16308212
D011374 Progesterone Progesterone results in decreased expression of RXRA mRNAdecreases expression 18037150
D015474 Isotretinoin Isotretinoin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]affects binding|increases expression|increases reaction 16632523
D012176 Retinoids Retinoids analog binds to and results in increased activity of RXRA proteinaffects binding|increases activity 16364638
C009166 retinol acetate retinol acetate results in increased expression of RXRA mRNAincreases expression 16772331
D012293 Rifampin [Rifampin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNAaffects cotreatment|decreases expression 16292757
D012293 Rifampin Rifampin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]affects binding|increases expression|increases reaction 16632523
C089730 rosiglitazone rosiglitazone results in increased expression of RXRAincreases expression 15254749
C089730 rosiglitazone [PPARG protein co-treated with RXRA protein] promotes the reaction [rosiglitazone results in increased expression of PPARGC1A mRNA]affects cotreatment|increases expression|increases reaction 16513826
C089730 rosiglitazone rosiglitazone results in increased activity of [RXRA protein binds to PPARG protein]affects binding|increases activity 15997096
C089730 rosiglitazone rosiglitazone binds to [PPARG protein binds to RXRA protein]affects binding 10882139
C089730 rosiglitazone [rosiglitazone binds to PPARG protein] which binds to RXRA proteinaffects binding 15715931
D012643 Selenium Selenium results in increased expression of RXRA proteinincreases expression 15318950
C017947 sodium arsenite sodium arsenite results in decreased expression of RXRA mRNAdecreases expression 15833926
C017947 sodium arsenite sodium arsenite results in decreased expression of RXRA proteindecreases expression 15833926
C017947 sodium arsenite sodium arsenite results in increased expression of RXRA mRNAincreases expression 19084030
C017947 sodium arsenite sodium arsenite results in decreased expression of RXRA mRNAdecreases expression 19822182
D013395 Sucrose [Sucrose co-treated with Orotic Acid] results in decreased expression of RXRA proteinaffects cotreatment|decreases expression 15670589
C033006 sudan III sudan III results in decreased expression of RXRA proteindecreases expression 15585952
D013449 Sulfonamides Sulfonamides analog binds to and results in decreased activity of RXRA proteinaffects binding|decreases activity 19095448
D013449 Sulfonamides Sulfonamides analog binds to and results in increased activity of RXRA proteinaffects binding|increases activity 19095448
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of RXRA mRNAdecreases expression 18336851
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of RXRA mRNAincreases expression 19684285
20106945
15075337
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of RXRA mRNAdecreases expression 17586704
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of RXRA mRNAincreases expression 15667827
D013755 Tetradecanoylphorbol Acetate benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased degradation of RXRA protein]decreases degradation|decreases reaction 12970875
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in decreased degradation of RXRA proteindecreases degradation 12970875
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in decreased localization of RXRA proteindecreases localization 12970875
D014212 Tretinoin [RARA protein binds to RXRA protein] promotes the reaction [Tretinoin results in increased degradation of NCOA3 protein]affects binding|increases degradation|increases reaction 16456540
D014212 Tretinoin RXRA protein promotes the reaction [Tretinoin results in increased expression of SOX3 mRNA]increases expression|increases reaction 17005281
D014212 Tretinoin RXRA protein promotes the reaction [Tretinoin results in increased expression of SOX3 protein]increases expression|increases reaction 17005281
D014212 Tretinoin Tretinoin affects the localization of RXRA proteinaffects localization 16636311
D014212 Tretinoin Tretinoin analog binds to and results in increased activity of RXRA proteinaffects binding|increases activity 16946489
D014212 Tretinoin Tretinoin binds to and results in increased activity of RXRA proteinaffects binding|increases activity 16946489
D014212 Tretinoin Tretinoin binds to [RXRA protein binds to RARA protein]affects binding 16757381
D014212 Tretinoin [Tretinoin binds to [RXRA protein binds to RARA protein]] which binds to PDK4 promoteraffects binding 16757381
D014212 Tretinoin [Tretinoin co-treated with alpha-Tocopherol co-treated with Okadaic Acid] results in decreased phosphorylation of RXRA proteinaffects cotreatment|decreases phosphorylation 15225641
D014212 Tretinoin [Tretinoin co-treated with alpha-Tocopherol] results in decreased phosphorylation of RXRA proteinaffects cotreatment|decreases phosphorylation 15225641
D014212 Tretinoin [Tretinoin co-treated with bisindolylmaleimide I] results in decreased phosphorylation of RXRA proteinaffects cotreatment|decreases phosphorylation 15225641
D014212 Tretinoin [Tretinoin co-treated with calphostin C] results in decreased phosphorylation of RXRA proteinaffects cotreatment|decreases phosphorylation 15225641
D014212 Tretinoin [Tretinoin co-treated with RARA protein co-treated with RXRA protein] results in increased expression of CYP26A1 mRNAaffects cotreatment|increases expression 17244623
D014212 Tretinoin Tretinoin promotes the reaction [[RARA protein binds to RXRA protein] which binds to NOS2A promoter]affects binding|increases reaction 17306764
D014212 Tretinoin Tretinoin promotes the reaction [RXRA protein binds to CD1D promoter]affects binding|increases reaction 17392484
D014212 Tretinoin Tretinoin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]affects binding|increases expression|increases reaction 16632523
D014212 Tretinoin Tretinoin results in decreased expression of RXRA proteindecreases expression 15194426
15375546
D014212 Tretinoin Tretinoin results in decreased phosphorylation of RXRA proteindecreases phosphorylation 15126328
D014212 Tretinoin Tretinoin results in increased activity of [RARA protein binds to RXRA protein]affects binding|increases activity 20008677
D014212 Tretinoin Tretinoin results in increased expression of and results in increased activity of RXRA proteinincreases activity|increases expression 16158052
D014212 Tretinoin Tretinoin results in increased expression of RXRA mRNAincreases expression 7556191
16517099
D014212 Tretinoin Tretinoin results in increased expression of RXRA proteinincreases expression 16636311
17005281
D014212 Tretinoin Tretinoin results in increased phosphorylation of RXRA proteinincreases phosphorylation 15225641
D014212 Tretinoin ZNF366 protein promotes the reaction [Tretinoin results in increased activity of [RARA protein binds to RXRA protein]]affects binding|increases activity|increases reaction 20008677
D014212 Tretinoin [Tretinoin binds to RXRA protein] which binds to NRL promoteraffects binding 16854989
D014212 Tretinoin Tretinoin promotes the reaction [[RARG protein binds to RXRA protein] which binds to CYP26A1 promoter]affects binding|increases reaction 16053444
D014212 Tretinoin Tretinoin results in decreased expression of RXRA proteindecreases expression 15646024
D014212 Tretinoin Tretinoin affects the localization of RXRA proteinaffects localization 17078027
D014212 Tretinoin Tretinoin results in increased activity of RXRA proteinincreases activity 15178767
D014212 Tretinoin Tretinoin results in increased expression of RXRA mRNAincreases expression 1312717
C011559 tributyltin [tributyltin binds to and results in increased activity of RXRA protein] which results in increased expression of CYP19A1 proteinaffects binding|increases activity|increases expression 15941851
C011559 tributyltin tributyltin inhibits the reaction [alitretinoin binds to RXRA protein]affects binding|decreases reaction 15941851
C011559 tributyltin tributyltin inhibits the reaction [triphenyltin hydroxide binds to RXRA protein]affects binding|decreases reaction 15941851
C012594 triphenyltin chloride triphenyltin chloride inhibits the reaction [alitretinoin binds to RXRA protein]affects binding|decreases reaction 15941851
C012594 triphenyltin chloride triphenyltin chloride inhibits the reaction [triphenyltin hydroxide binds to RXRA protein]affects binding|decreases reaction 15941851
C007567 triphenyltin hydroxide alitretinoin inhibits the reaction [triphenyltin hydroxide binds to RXRA protein]affects binding|decreases reaction 15941851
C007567 triphenyltin hydroxide tributyltin inhibits the reaction [triphenyltin hydroxide binds to RXRA protein]affects binding|decreases reaction 15941851
C007567 triphenyltin hydroxide triphenyltin chloride inhibits the reaction [triphenyltin hydroxide binds to RXRA protein]affects binding|decreases reaction 15941851
C007567 triphenyltin hydroxide triphenyltin hydroxide binds to and affects the activity of RXRA proteinaffects activity|affects binding 15941851
C007567 triphenyltin hydroxide [triphenyltin hydroxide binds to and results in increased activity of RXRA protein] which results in increased expression of CYP19A1 proteinaffects binding|increases activity|increases expression 15941851
C007567 triphenyltin hydroxide triphenyltin hydroxide inhibits the reaction [alitretinoin binds to RXRA protein]affects binding|decreases reaction 15941851
C057693 troglitazone troglitazone results in increased activity of [PPARG protein binds to RXRA protein]affects binding|increases activity 20008677
C057693 troglitazone ZNF366 protein promotes the reaction [troglitazone results in increased activity of [PPARG protein binds to RXRA protein]]affects binding|increases activity|increases reaction 20008677
C057693 troglitazone [troglitazone binds to PPARG protein] which binds to RXRA proteinaffects binding 15715931
D014501 Uranium Uranium results in decreased expression of RXRA mRNAdecreases expression 17118558
D014801 Vitamin A Vitamin A results in increased expression of RXRA mRNAincreases expression 16571146
D014801 Vitamin A [Vitamin A co-treated with RARA protein co-treated with RXRA protein] results in increased expression of CYP26A1 mRNAaffects cotreatment|increases expression 17244623
D014801 Vitamin A Vitamin A results in increased expression of RXRA proteinincreases expression 17219422
D014801 Vitamin A Vitamin A results in increased expression of RXRA mRNAincreases expression 16180333
D024482 Vitamin K 2 [Vitamin K 2 co-treated with 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid] results in decreased phosphorylation of RXRA proteinaffects cotreatment|decreases phosphorylation 17270033
D024482 Vitamin K 2 Vitamin K 2 results in decreased phosphorylation of RXRA proteindecreases phosphorylation 17270033
D015054 Zymosan Zymosan results in decreased expression of RXRA mRNAdecreases expression 16847310
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Capsaicin 18.0218926900
MESH:D000014 Abnormalities, Drug-Induced Isotretinoin 18.0218769834
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 18.026195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 18.0215322242 11752688 14514962
MESH:D000014 Abnormalities, Drug-Induced triphenyltin hydroxide 18.0217619067
MESH:D000015 Abnormalities, Multiple Isotretinoin 8.2318769834
MESH:D000015 Abnormalities, Multiple Vitamin A 8.2310992263
MESH:D000138 Acidosis Ammonium Chloride 2.7318287403
MESH:D017486 Acneiform Eruptions Isotretinoin 5.4316232082
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 9.1717505938
MESH:D000152 Acne Vulgaris Isotretinoin 9.1718769834 16185265
MESH:D058186 Acute Kidney Injury Capsaicin 3.7918460982
MESH:D055371 Acute Lung Injury Lipopolysaccharides 6.4711850527 18653653
MESH:D055371 Acute Lung Injury pirinixic acid 6.4718653653
MESH:D000230 Adenocarcinoma arsenic trioxide 10.2011798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 10.2020127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 10.2014692618
MESH:D000230 Adenocarcinoma Fenretinide 10.2010697514
MESH:D000230 Adenocarcinoma Indomethacin 10.2016537180
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 7.973712494
MESH:D000236 Adenoma Benzo(a)pyrene 7.976695378
MESH:D000236 Adenoma Indomethacin 7.9711497255
MESH:D018248 Adenoma, Liver Cell Phenobarbital 12.4817620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 12.4816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 12.4816835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.8515276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.0517306315 16712894
MESH:D000382 Agricultural Workers' Diseases Lindane 6.2412661182
MESH:D000382 Agricultural Workers' Diseases Paraquat 6.2411874814
OMIM:607154 ALLERGIC RHINITIS Etodolac 5.0416979129
MESH:D000505 Alopecia Capsaicin 7.2717569567
MESH:D000505 Alopecia Tretinoin 7.2715955085
MESH:D016301 Alveolar Bone Loss Indomethacin 4.5217225004
MESH:D000544 Alzheimer Disease Indomethacin 3.6617627676 15579461
MESH:D000544 Alzheimer Disease rosiglitazone 3.6619621015
MESH:D000740 Anemia Tetrachlorodibenzodioxin 10.7511748828
MESH:D000740 Anemia Vitamin A 10.7516960172
MESH:D000740 Anemia Zymosan 10.7518664788
MESH:D000741 Anemia, Aplastic Benzene 3.6911369114 17661222 14761424
MESH:D018798 Anemia, Iron-Deficiency Vitamin A 4.0516960172
MESH:D000799 Angioedema Acetaminophen 2.9910982225
MESH:D001014 Aortic Aneurysm Indomethacin 4.0510231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 8.9919183758
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 8.9910388637
MESH:D001161 Arteriosclerosis Dietary Fats 7.2015238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 7.2011256880
MESH:D018771 Arthralgia Indomethacin 4.322160914
MESH:D001169 Arthritis, Experimental Dexamethasone 12.7917659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 12.7915885639
MESH:D001169 Arthritis, Experimental Tretinoin 12.7916412693
MESH:D001169 Arthritis, Experimental Zymosan 12.7915944321 16872482 15142272 15188379 17659584
MESH:D001172 Arthritis, Rheumatoid Indomethacin 3.7911248219
MESH:D001172 Arthritis, Rheumatoid Tretinoin 3.7916292516
MESH:D001249 Asthma Tretinoin 4.0516456186
MESH:D001249 Asthma Vitamin A 4.0516732791
MESH:D001289 Attention Deficit Disorder with Hyperactivity Fatty Acids, Omega-3 4.2118448859
MESH:D001321 Autistic Disorder Acetaminophen 2.3618445737
MESH:D001321 Autistic Disorder Docosahexaenoic Acids 2.3618582451
MESH:D001321 Autistic Disorder Fatty Acids, Omega-3 2.3616920077
MESH:D001321 Autistic Disorder Glutathione 2.3619056591 16917939 19267885 18929414
MESH:D001471 Barrett Esophagus Tretinoin 3.6016935849
MESH:D001477 Bartter Syndrome Indomethacin 4.1610684365
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.1611289319 1440618
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 20.8316206674
MESH:D001778 Blood Coagulation Disorders Clofibrate 20.8319483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 20.8319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 20.8312125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 20.8316206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 2.9415340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.1715746008
MESH:D001855 Bone Marrow Diseases Benzene 4.3816183116
MESH:D001862 Bone Resorption bisphenol A 3.1111985600
MESH:D001919 Bradycardia Capsaicin 4.2318207255
MESH:D001929 Brain Edema Indomethacin 4.1711481608
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.4817868700
MESH:D001930 Brain Injuries Progesterone 3.4415665606 15845082 15380490
MESH:D002545 Brain Ischemia beta Carotene 12.5016157235
MESH:D002545 Brain Ischemia Capsaicin 12.5019211983
MESH:D002545 Brain Ischemia Indomethacin 12.5012524144
MESH:D001932 Brain Neoplasms Fenretinide 3.6216187019
MESH:D001943 Breast Neoplasms alitretinoin 10.0916344269
MESH:D001943 Breast Neoplasms Benzene 10.0917162533 11921183
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 10.0920146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 10.0917123778
MESH:D001943 Breast Neoplasms Calcitriol 10.0911237771
MESH:D001943 Breast Neoplasms Dietary Fats 10.0920435547
MESH:D001943 Breast Neoplasms Fenretinide 10.0916601279
MESH:D001943 Breast Neoplasms Indomethacin 10.0917401462
MESH:D001943 Breast Neoplasms LG 100268 10.0916818667
MESH:D001943 Breast Neoplasms Lindane 10.0914688026
MESH:D001943 Breast Neoplasms Progesterone 10.0915562024 16175315 17614352
MESH:D001943 Breast Neoplasms Retinoids 10.0917368321 19340624 17491551
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 10.0920435547
MESH:D001943 Breast Neoplasms Tretinoin 10.0916873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 10.2416813970
MESH:D001997 Bronchopulmonary Dysplasia Vitamin A 10.2417377406 17426644
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.5511589617
MESH:D002056 Burns Indomethacin 3.8910459503
MESH:D002100 Cachexia Indomethacin 4.1716537180 15625704 15141370 11239499
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.1216835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.3016168501
MESH:D006528 Carcinoma, Hepatocellular 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid 20.6417270033
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 20.643581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 20.643084413
MESH:D006528 Carcinoma, Hepatocellular anthra(1,9-cd)pyrazol-6(2H)-one 20.6419418558
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 20.6416217749 15073043 15553829 14691202 11135700
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 20.6416270382 17159502
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 20.6416391822
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 20.6420935162 1701930 6705139 20007298 17173139
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 20.6417306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 20.641917145
MESH:D006528 Carcinoma, Hepatocellular Vitamin K 2 20.6417270033
MESH:D002278 Carcinoma in Situ bisphenol A 4.1517123778
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 3.8911053908
MESH:D018276 Carcinoma, Medullary Indomethacin 4.5118791128 14736730 11352223
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.0219014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 5.027296757
MESH:D002292 Carcinoma, Renal Cell Indomethacin 5.0217341418
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.3712490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 23.3120419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 23.3111237771
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 23.3116274795
MESH:D002294 Carcinoma, Squamous Cell Glutathione 23.3117015178
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 23.3112636206 15482327
MESH:D002294 Carcinoma, Squamous Cell Isotretinoin 23.3111237771
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 23.3118572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 23.3118922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 23.3116051514 16096774
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 1.8418670907 16120746 18850075
MESH:D002386 Cataract Acetaminophen 5.3510977129
MESH:D002386 Cataract Tretinoin 5.3517460283
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 14.557505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 14.5520889678
MESH:D002471 Cell Transformation, Neoplastic Aphidicolin 14.558243401
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 14.551399818
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 14.5519524636 20056578
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.434080065
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 10.2016154183
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 10.2016129372
MESH:D015362 Child Nutrition Disorders Vitamin A 4.6216153327
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.4416835633
MESH:D002764 Cholecystitis Indomethacin 4.3211181007
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 18.379022650 19486331
MESH:D002779 Cholestasis Ethinyl Estradiol 18.3715861022 17333356 16105132 17110522 11677210 17681005 16919318
MESH:D002779 Cholestasis Lithocholic Acid 18.3719965603
MESH:D002779 Cholestasis pirinixic acid 18.3719176532
MESH:D002779 Cholestasis Vitamin A 18.3716175620
MESH:D002822 Choriocarcinoma Tretinoin 4.3016461808
MESH:D002869 Chromosome Aberrations triphenyltin hydroxide 6.1510477351
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 10.5416354765 15340226 8697196 12621046 15668235
MESH:D002972 Cleft Palate Tretinoin 10.549407595
MESH:D002972 Cleft Palate triphenyltin hydroxide 10.5417619067
MESH:D002972 Cleft Palate Vitamin A 10.5416054864
MESH:D003092 Colitis Selenium 6.8017936198
MESH:D003092 Colitis Tretinoin 6.8017035595
MESH:D003110 Colonic Neoplasms 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid 8.4716596235
MESH:D003110 Colonic Neoplasms Dexamethasone 8.4715824018
MESH:D003110 Colonic Neoplasms Etodolac 8.4716004971
MESH:D003110 Colonic Neoplasms Indomethacin 8.4715786552 11260862 15963497 15637740 15936596 15625704
MESH:D003110 Colonic Neoplasms Vitamin A 8.4717219422 16267017
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.8520501625
MESH:D015179 Colorectal Neoplasms Etodolac 3.8511076880
MESH:D015179 Colorectal Neoplasms Fenretinide 3.8517273769
MESH:D015179 Colorectal Neoplasms Indomethacin 3.8511197048 18059344 12606626 17054584
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.3414669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.3812609071
MESH:D018352 Coronavirus Infections Indomethacin 4.8617302372
MESH:D003371 Cough Capsaicin 4.3310350223
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 11.3410525206
MESH:D019465 Craniofacial Abnormalities Benzene 11.3415643154
MESH:D019465 Craniofacial Abnormalities Dexamethasone 11.3417728286
MESH:D019465 Craniofacial Abnormalities Isotretinoin 11.3418769834 9879862
MESH:D019465 Craniofacial Abnormalities nitrofen 11.3411405365
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 11.3415322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 11.348800419 14991402 10589399 9125849 17551590 16925845 9142499 9211117 9224671 9664655
MESH:D019465 Craniofacial Abnormalities Vitamin A 11.3410992263
MESH:D003550 Cystic Fibrosis Docosahexaenoic Acids 6.8819747007
MESH:D003550 Cystic Fibrosis Glutathione 6.8819747007
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.3115213294
MESH:D003872 Dermatitis Benzene 3.9515902427
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 4.4512868966 11298694 18759878 14531868 11906362 8970840 2524372 8156756
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 4.4512438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 1.9618249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 2.723621924 2952479
MESH:D003920 Diabetes Mellitus ethyl(E,E,E)-7-(2-n-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-3-yl)-6-fluorp-3-methylocta-2,4,6-trienoate 7.8615997096
MESH:D003920 Diabetes Mellitus rosiglitazone 7.8617446233
MESH:D003921 Diabetes Mellitus, Experimental triphenyltin chloride 4.789202216
MESH:D003922 Diabetes Mellitus, Type 1 Vitamin A 3.1816506275
MESH:D003924 Diabetes Mellitus, Type 2 alpha-Tocopherol 7.8416506275
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 7.8412642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 7.8417107852
MESH:D003924 Diabetes Mellitus, Type 2 troglitazone 7.8416023994
MESH:D003925 Diabetic Angiopathies troglitazone 4.8212601628
MESH:D003929 Diabetic Neuropathies Progesterone 3.6717187935
MESH:D003967 Diarrhea Dexamethasone 5.677237001
MESH:D003967 Diarrhea Indomethacin 5.677237001 7907874
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 8.316679447 9328219 16192314 6482804 8291058 11289319 18648102 9022650 18289764 7440962 9653073 1440618 18692083
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 8.3111529661 12958197 16781746 11287661 14550746 10915739 12594235 12392966 11743745 16177239 19923254 19085960 12153990 15968718 19164858 16227642 14725611 14986274 12540782 16109766 18713872 11834606 2444490 19370779 10663392 19416960 19739265 16393943 11739529 11461765 15619225 18071297 12705907 17522070 10774834 11421492 19420014 17906064 16485898 16081117 17562736
MESH:D056486 Drug-Induced Liver Injury Selenium 8.3115131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 8.3120420201
MESH:D056486 Drug-Induced Liver Injury troglitazone 8.3114986274
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.2419426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.1111462148
MESH:D015352 Dry Eye Syndromes Vitamin A 4.9616146918
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.3118446180 17190690 18043480 16133044 12774134 16326151
MESH:D004381 Duodenal Ulcer Capsaicin 7.0211535926 10671773
MESH:D004381 Duodenal Ulcer Indomethacin 7.0217045617 17202747 17329845 10671773 16699067 11991626 17151854 11595431 11535926 11595415 17351913
MESH:D050171 Dyslipidemias Clofibrate 6.6616707586
MESH:D050171 Dyslipidemias Dietary Fats 6.6618367378
MESH:D004421 Dystonia Phenobarbital 3.221851702
MESH:C538011 Eales disease Vitamin A 4.779068938
MESH:D004480 Ectromelia Vitamin A 4.9716054864
MESH:D004485 Eczema Dexamethasone 3.6612438553
MESH:D004487 Edema bisindolylmaleimide I 33.568273558
MESH:D004487 Edema Dexamethasone 33.5619703484
MESH:D004487 Edema Indomethacin 33.567990266 7907874 8273558 16100529 8985016 10653021 19703484
MESH:D004487 Edema L 663536 33.567990266
MESH:D004487 Edema perfluorooctanoic acid 33.5612083418 17259670
MESH:D004487 Edema pirinixic acid 33.5612083418
MESH:D004487 Edema rosiglitazone 33.5612083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 33.5611000095 12711302
MESH:D004487 Edema Tetradecanoylphorbol Acetate 33.569599246 11698051 7812673 16716910 15177302 8113982 8273558
MESH:D004487 Edema Zymosan 33.567907874
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 9.1216714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 9.1218230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental 15-deoxy-delta(12,14)-prostaglandin J2 15.5116844232
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 15.5115138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 15.5112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 15.5117692515
MESH:D018159 Endolymphatic Hydrops Dimethyl Sulfoxide 5.7120641076
MESH:D016889 Endometrial Neoplasms Tretinoin 2.5116569247
MESH:D004715 Endometriosis Indomethacin 11.0215652904
MESH:D004715 Endometriosis Progesterone 11.0216134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 11.029294722 10568697
MESH:D019446 Endotoxemia Indomethacin 7.8818509659
MESH:D019446 Endotoxemia Lipopolysaccharides 7.8815821434 15328337 17637181
MESH:D004751 Enteritis Indomethacin 3.9017763956 10567023 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.1617980183
MESH:D004802 Eosinophilia Indomethacin 3.2511298111
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.293659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.033922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.3920417680
MESH:D004832 Epilepsy, Absence Phenobarbital 2.826401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.437750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.193659116
MESH:D004935 Esophageal Diseases Capsaicin 4.8719566590
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 10.423581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.4220426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 10.4212903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 10.4216530937
MESH:D004938 Esophageal Neoplasms Indomethacin 10.4211005569
MESH:D004942 Esophagitis, Peptic Bile Acids and Salts 5.7011346197
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 6.6211564622
MESH:D005124 Eye Abnormalities Tretinoin 6.6216938888 9664655
MESH:D015785 Eye Diseases, Hereditary Retinoids 5.1816968212
MESH:D005234 Fatty Liver 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid 25.5021071580
MESH:D005234 Fatty Liver arsenic trioxide 25.5015073043
MESH:D005234 Fatty Liver Clofibrate 25.5019224547
MESH:D005234 Fatty Liver Dietary Fats 25.5018296743 17967931 19004024 19551842
MESH:D005234 Fatty Liver Ethinyl Estradiol 25.5015345470
MESH:D005234 Fatty Liver pirinixic acid 25.5020131406 19236843
MESH:D005234 Fatty Liver rosiglitazone 25.5019196556
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 8.4411858732
MESH:D005313 Fetal Death triphenyltin hydroxide 8.442087686
MESH:D005327 Fetal Resorption Vitamin A 4.5116054864
MESH:D005334 Fever Indomethacin 6.8910431976 11852909 17627676
MESH:D005334 Fever Lipopolysaccharides 6.899205823 11852909
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.166705139
MESH:D005354 Fibrosarcoma Indomethacin 4.0610962813
MESH:D005355 Fibrosis Dietary Fats 14.5518296743
MESH:D005355 Fibrosis Indomethacin 14.5517994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.5520067830
MESH:D005355 Fibrosis Tretinoin 14.5517994277
MESH:D005499 Folliculitis Indomethacin 4.3211298111
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.4616904648
MESH:D005756 Gastritis Acetaminophen 8.3216983495
MESH:D005756 Gastritis Indomethacin 8.3215046732
MESH:D005833 Genital Neoplasms, Female sodium arsenite 3.8416452187
MESH:D005909 Glioblastoma Capsaicin 15.9318405923
MESH:D005909 Glioblastoma Fenretinide 15.9316187019
MESH:D005909 Glioblastoma Indomethacin 15.9312870263
MESH:D005909 Glioblastoma Okadaic Acid 15.9317312396
MESH:D005909 Glioblastoma Tretinoin 15.9317312396
MESH:D005910 Glioma Indomethacin 2.8216487511 18371953
MESH:D005911 Gliosis Paraquat 4.3111124998
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.5911849393
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.257505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.7410696789
MESH:D006073 Gout Indomethacin 4.5111248219
MESH:D006258 Head and Neck Neoplasms Indomethacin 9.6315482327
MESH:D006258 Head and Neck Neoplasms Retinoids 9.6317368321
MESH:D006258 Head and Neck Neoplasms Tretinoin 9.6316096774
MESH:D034381 Hearing Loss Dimethyl Sulfoxide 4.4420641076
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.3016084493
MESH:D006356 Heartburn Capsaicin 4.8719566590
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 15.5420471113
MESH:D006330 Heart Defects, Congenital nitrofen 15.5416080930
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 15.5411294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 15.549664655 14991402
MESH:D006330 Heart Defects, Congenital Vitamin A 15.5416080930 10992263
MESH:D006333 Heart Failure pirinixic acid 5.0220558911
MESH:D006333 Heart Failure Selenium 5.0217162251
MESH:D006402 Hematologic Diseases Benzene 3.8716183116
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.6416366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.5711000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 3.8115633222
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 6.996705139
MESH:D006505 Hepatitis Zymosan 6.9919110552
MESH:D019698 Hepatitis C, Chronic Indomethacin 3.8815135802
MESH:D006529 Hepatomegaly 1,4-bis(2-(3,5-dichloropyridyloxy))benzene 18.6116109766
MESH:D006529 Hepatomegaly perfluorooctanoic acid 18.613609246
MESH:D006529 Hepatomegaly Phenobarbital 18.6116109766
MESH:D006529 Hepatomegaly pirinixic acid 18.6119176532 16221962 18467677 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 18.6115340226 16120746 12621046
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 7.597520565
MESH:D006548 Hernia, Diaphragmatic nitrofen 7.5916292651 11409163 15578192 15707848 10370016 12759764 16863852 10898222 11057544 16490937 15764645 10898224 10646786 12904592 9859898 15793718 7576705 15756563 17618886 8863223 10359170 18958481 15185205 9575882 10693666 7760232 11051153 11076806 10541330 17245593 18280291 16720372 9476886 15088113 10370017 15136996 16473863 12194112 16080930 17270546 11588001 18280292 12547725 7520565 12407540 12505043 12746050 11685700 11584395 9698600 11329586 12021965 9473106
MESH:D006548 Hernia, Diaphragmatic Vitamin A 7.5916877224 17436238 16863852 16292552 15707848 16490937
MESH:D015658 HIV Infections beta Carotene 5.5616960176
MESH:D015658 HIV Infections Vitamin A 5.5616960176
MESH:D006679 HIV Seropositivity Vitamin A 4.7617209195
MESH:D006689 Hodgkin Disease sodium arsenite 2.4612676792
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.1915340226 18606429 16959395 8697196 16354765
MESH:D006930 Hyperalgesia Acetaminophen 21.6616870215
MESH:D006930 Hyperalgesia Capsaicin 21.6617043245 17434803
MESH:D006930 Hyperalgesia Indomethacin 21.6612727271
MESH:D006930 Hyperalgesia perfluorooctanoic acid 21.6612083418
MESH:D006930 Hyperalgesia rosiglitazone 21.6612083418
MESH:D006930 Hyperalgesia Tretinoin 21.6616870215
MESH:D034321 Hyperamylasemia Indomethacin 4.8617883296
MESH:D006937 Hypercholesterolemia Dietary Fats 2.8421332399
MESH:D006940 Hyperemia Indomethacin 4.1712524144
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.7516778211
MESH:D006943 Hyperglycemia pirinixic acid 7.4420558911
MESH:D006943 Hyperglycemia triphenyltin hydroxide 7.446714370
MESH:D006949 Hyperlipidemias Dietary Fats 6.7621332399
MESH:D006949 Hyperlipidemias Indomethacin 6.7617546600
MESH:D006951 Hyperlipoproteinemias Fatty Acids, Unsaturated 5.4218435438
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.1215034207
MESH:D006973 Hypertension Benzene 6.3117940673
MESH:D006973 Hypertension Dexamethasone 6.3117042910
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 6.3118670907 18850075
MESH:D006976 Hypertension, Pulmonary L 663536 4.5314726295
MESH:D006986 Hypervitaminosis A Vitamin A 5.3116054864
MESH:D007021 Hypospadias Ethinyl Estradiol 2.9916945680 16569931
MESH:D007077 Ileal Diseases Indomethacin 4.1718306037 10574470
MESH:D007079 Ileitis Indomethacin 4.5110647630 10651667 16133968
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.5216133044
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.5815869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.6812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 7.6917937319
MESH:D007248 Infertility, Male Paraquat 7.694850670
MESH:D007248 Infertility, Male sodium arsenite 7.6915346721 12646999
MESH:D007249 Inflammation bisindolylmaleimide I 37.468273558
MESH:D007249 Inflammation Capsaicin 37.4616956363
MESH:D007249 Inflammation Dexamethasone 37.468960868 11099482
MESH:D007249 Inflammation Dietary Fats 37.4620412841
MESH:D007249 Inflammation Fatty Acids, Omega-3 37.4617296493
MESH:D007249 Inflammation Indomethacin 37.4612568917 7812673 3291741
MESH:D007249 Inflammation Lipopolysaccharides 37.469205823 17237260 12878042 17963957 17255318
MESH:D007249 Inflammation perfluorooctanoic acid 37.4612083418
MESH:D007249 Inflammation Progesterone 37.4615869954
MESH:D007249 Inflammation rosiglitazone 37.4612083418
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 37.4612200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 37.4615177302 7812673 7562506 11698051 8273558
MESH:D007249 Inflammation Zymosan 37.4611289658 8014878
MESH:D007251 Influenza, Human Selenium 3.3516624496
MESH:D007333 Insulin Resistance bisphenol A 12.7116393666
MESH:D007333 Insulin Resistance Dietary Fats 12.7111836018 18457598
MESH:D007333 Insulin Resistance pirinixic acid 12.7116306350
MESH:D007333 Insulin Resistance rosiglitazone 12.7116306350
MESH:D007410 Intestinal Diseases Indomethacin 7.1818236018 17329856 11686837 15831440 15610444 11713966 10210152 17994277 11855677
MESH:D007410 Intestinal Diseases Tretinoin 7.1817994277
MESH:D019586 Intracranial Hypertension Indomethacin 11.3615241188
MESH:D019586 Intracranial Hypertension Vitamin A 11.3615955940
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 3.8517255318
MESH:D043183 Irritable Bowel Syndrome Zymosan 5.0017553498
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.168074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 7.4016580747
MESH:D007569 Jaw Abnormalities Tretinoin 7.4017551590 15992940
MESH:D007579 Jejunal Diseases Indomethacin 4.1718306037 10574470 16133968
MESH:D017492 Keratosis, Seborrheic alitretinoin 4.8016144296
MESH:D007674 Kidney Diseases Acetaminophen 6.9315629191 12587719
MESH:D007674 Kidney Diseases Indomethacin 6.9317190690
MESH:D007674 Kidney Diseases sodium arsenite 6.9320008137
MESH:D007676 Kidney Failure, Chronic Selenium 3.1316518626
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 2.296582329
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.2110320625 11703811 12228301
MESH:D007938 Leukemia arsenic trioxide 7.6215070760
MESH:D007938 Leukemia Benzene 7.6214694614 18335105 15935818 17119257
MESH:D007938 Leukemia Tretinoin 7.6217143497
MESH:D004915 Leukemia, Erythroblastic, Acute troglitazone 5.2916085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 7.5317077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Docosahexaenoic Acids 7.5317077332
MESH:D007948 Leukemia, Monocytic, Acute anthra(1,9-cd)pyrazol-6(2H)-one 9.0016972261
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 9.0016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 6.3614633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 6.3616572323 10785260 15631656
MESH:D007951 Leukemia, Myeloid arsenic trioxide 16.7019077051
MESH:D007951 Leukemia, Myeloid Benzene 16.7017506065
MESH:D007951 Leukemia, Myeloid Retinoids 16.7016482212
MESH:D007951 Leukemia, Myeloid Tretinoin 16.7019285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 6.7517050201 16968895 20471514 16467208 19850784
MESH:D015470 Leukemia, Myeloid, Acute Benzene 6.7519478238
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 6.7518360721
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 6.7516294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 5.6215213294 17649720 17869043 16330433 12679006 19642359 16966277 17712046 15622746 16823087 19225113 16112521 19075265 15336539 16891316 12712474 12018890 17217047 11161223 16331271 11468182 15748426 9834237 17107899 19035177
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 5.6217368321 16331271 16935935 17294898 16891316 16823087 19029980 15748426 17301526 16140955 19075265 17339181 19225113 19035177 12679006 17107899 17506722 19642359 17361223 17217047 17649720 9834237 16788101 17712046 16766008
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.5516882451
MESH:D007964 Leukocytosis Indomethacin 4.5216537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 4.8617980183
MESH:D007970 Leukopenia Lipopolysaccharides 3.8615821434
MESH:D007972 Leukoplakia, Oral Fenretinide 5.1916707609
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 4.398812269
MESH:D017880 Limb Deformities, Congenital Tretinoin 6.359224671
MESH:D017880 Limb Deformities, Congenital Vitamin A 6.3516054864
MESH:D008101 Liver Abscess, Amebic Indomethacin 4.8611479899
MESH:D008103 Liver Cirrhosis Dietary Fats 8.0418296743
MESH:D008103 Liver Cirrhosis Phenobarbital 8.0421047994
MESH:D008103 Liver Cirrhosis Vitamin A 8.0416256175
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.6115034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 12.0916718785
MESH:D008106 Liver Cirrhosis, Experimental Dimethyl Sulfoxide 12.0911682029
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 12.0918194892
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 12.0912878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 12.0915474484
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 12.0917347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 12.0912878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 12.0916248980 18397230
MESH:D008106 Liver Cirrhosis, Experimental Vitamin A 12.0916248980
MESH:D008107 Liver Diseases Acetaminophen 14.4712587719 12969438 11587558 19014921 16610002 19784758 19460945 16611625
MESH:D008107 Liver Diseases Capsaicin 14.4716956363
MESH:D008107 Liver Diseases Docosahexaenoic Acids 14.4717056761
MESH:D008107 Liver Diseases Lindane 14.471715830
MESH:D008107 Liver Diseases Phenobarbital 14.4719363144
MESH:D008107 Liver Diseases Sulfonamides 14.4714986274
MESH:D008107 Liver Diseases Vitamin A 14.4716175620
MESH:D008108 Liver Diseases, Alcoholic Vitamin A 4.3416762690
MESH:D017114 Liver Failure, Acute Acetaminophen 2.4916871587 17185352
MESH:D008113 Liver Neoplasms 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid 25.1621071580
MESH:D008113 Liver Neoplasms arsenic trioxide 25.1614682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 25.1621137059 20195826
MESH:D008113 Liver Neoplasms Clofibric Acid 25.1617602206
MESH:D008113 Liver Neoplasms Methapyrilene 25.1615890375
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 25.1614757943 18709148
MESH:D008113 Liver Neoplasms Phenobarbital 25.1619482888 19812893 15975961 8742319 21047994 19073162
MESH:D008113 Liver Neoplasms pirinixic acid 25.1616377806 15890375 20007298
MESH:D008113 Liver Neoplasms sodium arsenite 25.1616712894 15276417
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 25.1616984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 19.366587162 1399818 598648 3712494
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 19.3620377131
MESH:D008114 Liver Neoplasms, Experimental Benzene 19.3612562636
MESH:D008114 Liver Neoplasms, Experimental beta Carotene 19.3617113696
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 19.3618308698 17172636 1399818 2563599 6150874
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 19.3612151625
MESH:D008114 Liver Neoplasms, Experimental Vitamin A 19.3617113696
MESH:D008133 Long QT Syndrome arsenic trioxide 2.6915213294
MESH:D008171 Lung Diseases nitrofen 9.069859898 16863852 9614859 17245593
MESH:D008171 Lung Diseases sodium arsenite 9.0619095001
MESH:D008171 Lung Diseases Vitamin A 9.0616863852
MESH:D017563 Lung Diseases, Interstitial Benzene 3.9614698565
MESH:D055370 Lung Injury Asbestos, Crocidolite 6.6117365036
MESH:D055370 Lung Injury Lipopolysaccharides 6.6121114838
MESH:D008175 Lung Neoplasms 9-deoxy-delta-9-prostaglandin D2 23.2815899809
MESH:D008175 Lung Neoplasms alitretinoin 23.2816413115
MESH:D008175 Lung Neoplasms alpha-Tocopherol 23.2816401635
MESH:D008175 Lung Neoplasms arsenic trioxide 23.2819825857 11798837
MESH:D008175 Lung Neoplasms Benzene 23.2812562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 23.2818520028 18569708 17053015 18816296 6695378 20464547 20869020 20064080 20135361
MESH:D008175 Lung Neoplasms beta Carotene 23.2816401635
MESH:D008175 Lung Neoplasms Dexamethasone 23.2815824018 11195469
MESH:D008175 Lung Neoplasms Indomethacin 23.2811497255 16537180 11053908
MESH:D008175 Lung Neoplasms Isotretinoin 23.2815899809
MESH:D008175 Lung Neoplasms L 663536 23.2815899809
MESH:D008175 Lung Neoplasms sodium arsenite 23.2815276417 17306315 17077188 16712894 19931552
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 23.2819555203 11884234
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 23.2811807781
MESH:D008178 Lupus Erythematosus, Cutaneous Rifampin 5.2911422169
MESH:D008180 Lupus Erythematosus, Systemic Rifampin 3.6711422169
MESH:D008223 Lymphoma Benzene 3.1117584886 17119257
MESH:D015674 Mammary Neoplasms, Animal Benzene 3.6212562636
MESH:D008325 Mammary Neoplasms, Experimental Benzene 19.4311921183
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 19.4310697514
MESH:D008325 Mammary Neoplasms, Experimental LG 100268 19.4312374698
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 19.4311408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 19.4316827153
MESH:D008325 Mammary Neoplasms, Experimental Selenium 19.4315318939
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 19.438985016
MESH:D008415 Mastocytosis Retinoids 5.7516953078
MESH:D008527 Medulloblastoma Tretinoin 2.3717453147
MESH:D008545 Melanoma Fenretinide 5.4516270382
MESH:D008545 Melanoma Isotretinoin 5.4517237267
MESH:D008545 Melanoma sodium arsenite 5.4516487513 19082730
MESH:D008545 Melanoma Tretinoin 5.4516752155
MESH:D008546 Melanoma, Experimental Acetaminophen 2.7519513568
MESH:D008591 Meningomyelocele Tretinoin 3.6016940565
MESH:D008654 Mesothelioma Asbestos, Crocidolite 4.9116966607 18303189 16166281
MESH:D008654 Mesothelioma Selenium 4.9115107826
MESH:D024821 Metabolic Syndrome X rosiglitazone 3.6717261469
MESH:D008881 Migraine Disorders Indomethacin 3.0511903285
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 10.6016381670
MESH:D009062 Mouth Neoplasms Fenretinide 10.6016274795
MESH:D009062 Mouth Neoplasms Indomethacin 10.6012636206
MESH:D009101 Multiple Myeloma arsenic trioxide 15.9414977855 11468182 19549372 19417148 15949261
MESH:D009101 Multiple Myeloma Benzene 15.9417119195
MESH:D009101 Multiple Myeloma Capsaicin 15.9417505005
MESH:D009101 Multiple Myeloma Dexamethasone 15.9415744524 15867202 16118317
MESH:D009101 Multiple Myeloma Vitamin A 15.9416374440
MESH:D009102 Multiple Organ Failure Zymosan 4.4312879239 15259001 15241586 18160304 12130978 10479408 15213630 17724436 15834315 10890648
MESH:D009135 Muscular Diseases pirinixic acid 2.6916239165
MESH:D009139 Musculoskeletal Abnormalities triphenyltin hydroxide 5.3817619067
MESH:D009164 Mycobacterium Infections Rifampin 4.7018474467
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.8218349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 9.1516105982 16882451
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 9.159809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 9.1517596541
MESH:D009203 Myocardial Infarction alpha-Tocopherol 4.6819595682
MESH:D009203 Myocardial Infarction pirinixic acid 4.6819151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.3312213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.2716411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.6417484760
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.1616624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 4.503581430
MESH:D009362 Neoplasm Metastasis Indomethacin 4.5011053908 16537180 11239499
MESH:D009369 Neoplasms alitretinoin 19.6316946489
MESH:D009369 Neoplasms Benzo(a)pyrene 19.6311141357
MESH:D009369 Neoplasms beta Carotene 19.6317051425
MESH:D009369 Neoplasms Fenretinide 19.6315958647 17353921
MESH:D009369 Neoplasms Lindane 19.6312807735 16818664
MESH:D009369 Neoplasms pirinixic acid 19.6317405874
MESH:D009369 Neoplasms sodium arsenite 19.6311559025
MESH:D009369 Neoplasms Tretinoin 19.6316946489 16594593
MESH:D009374 Neoplasms, Experimental Indomethacin 6.5815625704 10663608
MESH:D009374 Neoplasms, Experimental sodium arsenite 6.5820056578
MESH:D009410 Nerve Degeneration Paraquat 3.0516893418
MESH:D009421 Nervous System Malformations bisphenol A 11.7711399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 11.7714600291
MESH:D009421 Nervous System Malformations Tretinoin 11.779125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 20.606679447
MESH:D009436 Neural Tube Defects arsenic trioxide 20.6010525206
MESH:D009436 Neural Tube Defects Benzene 20.6015643154
MESH:D009436 Neural Tube Defects sodium arsenite 20.6012854658
MESH:D009436 Neural Tube Defects Tretinoin 20.609142499
MESH:D009436 Neural Tube Defects Vitamin A 20.6017400914
MESH:D009447 Neuroblastoma Isotretinoin 3.5417368321
MESH:D019636 Neurodegenerative Diseases Acetaminophen 6.0618514411
MESH:D019636 Neurodegenerative Diseases Indomethacin 6.0612349958
MESH:D020078 Neurogenic Inflammation Capsaicin 4.3117961222
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 4.8416303764
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 9.349802331
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 9.349802331
MESH:D009765 Obesity Capsaicin 5.7219056576
MESH:D009765 Obesity Dietary Fats 5.7217217161 20518802 20132043 21332399 11836018 18674790 19632207 18457598 16723640
MESH:D009765 Obesity pirinixic acid 5.7220558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.326374098
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 6.704026338 6482804
MESH:D009784 Occupational Diseases Benzene 6.7015612468 17178637 15913788 17119257 15727169 15935809 16737584 15576619 17479406
MESH:D009845 Oligospermia triphenyltin hydroxide 5.3516806747
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.163988306
MESH:D010003 Osteoarthritis Indomethacin 3.107009135
MESH:D010018 Osteomalacia Phenobarbital 3.5317016548
MESH:D010049 Ovarian Diseases bisphenol A 4.1511985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 14.1116624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Benzene 14.1112562636
MESH:D010051 Ovarian Neoplasms Fenretinide 14.1116133793
MESH:D010051 Ovarian Neoplasms Progesterone 14.1117393432 16525653
MESH:D010051 Ovarian Neoplasms sodium arsenite 14.1115276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 14.1116936753
MESH:D010146 Pain Acetaminophen 10.4716870215
MESH:D010146 Pain Capsaicin 10.4717043245 17084039 17434803 19081190 16996476 18987195
MESH:D010146 Pain Indomethacin 10.4717440234 13679232 3291741 17627676
MESH:D010146 Pain Tretinoin 10.4716870215
MESH:D010149 Pain, Postoperative Indomethacin 3.8318702446 12538197
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 15.3015580305
MESH:D010190 Pancreatic Neoplasms Fenretinide 15.3015580305
MESH:D010190 Pancreatic Neoplasms L 663536 15.3012384795
MESH:D010190 Pancreatic Neoplasms Phenobarbital 15.3016965848
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 15.3015976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 15.3015976015
MESH:D010195 Pancreatitis Indomethacin 3.1617883296 15028970
MESH:D016584 Panic Disorder Ethinyl Estradiol 2.9011578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 6.707296757
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 6.708330346 12065085 18404319 18922899
MESH:D010235 Paraganglioma arsenic trioxide 3.3819927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 4.8616537180
MESH:D010300 Parkinson Disease Paraquat 2.4411124998 12911755 16140633 15824117 11445065 15451049 16510128 11181820
MESH:D010302 Parkinson Disease, Secondary Paraquat 3.6116190885
MESH:D020734 Parkinsonian Disorders Indomethacin 3.3812349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 4.8611903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.3912520081
MESH:D010437 Peptic Ulcer Indomethacin 4.3111148446
MESH:D010518 Periodontitis Indomethacin 4.0617225004
MESH:D010538 Peritonitis Zymosan 4.0717826846 11985352 19088179 15259001 19641140 18760300 15979727 14761945 18977430 18557954 17371808
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 3.626228378
MESH:D010954 Plasmacytoma Selenium 4.0315087411
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.0710923243
MESH:D011014 Pneumonia Lipopolysaccharides 8.3512224865 11605937
MESH:D011014 Pneumonia Paraquat 8.3512504350
MESH:D017499 Porokeratosis alitretinoin 5.1516144296
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.7618163543
MESH:D011230 Precancerous Conditions Phenobarbital 2.902563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.0121297632
MESH:D047928 Premature Birth Indomethacin 4.3017000239
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 16.5310548101
MESH:D011297 Prenatal Exposure Delayed Effects Isotretinoin 16.5318769834
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 16.5317132714
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 16.5311896295 11118676 11399792 11222880
MESH:D011470 Prostatic Hyperplasia Calcitriol 3.9415572423
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 3.4420887781
MESH:D011471 Prostatic Neoplasms marker/mechanism 15318950
MESH:D011471 Prostatic Neoplasms AGN 194204 2.4416000583
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.4419131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.4417292933
MESH:D011471 Prostatic Neoplasms bisphenol A 2.4416740699
MESH:D011471 Prostatic Neoplasms Calcitriol 2.4416289102 15754350 12479363 18247401 16644109
MESH:D011471 Prostatic Neoplasms Fenretinide 2.4417024972
MESH:D011471 Prostatic Neoplasms Lindane 2.4414688026 12661182
MESH:D011471 Prostatic Neoplasms Retinoids 2.4416166285 16724957
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.4416039940
MESH:D011507 Proteinuria Indomethacin 6.7611849393
MESH:D011507 Proteinuria Tretinoin 6.7616636307
MESH:D011537 Pruritus Ethinyl Estradiol 7.3415861022 16919318
MESH:D011537 Pruritus L 663536 7.3417827870
MESH:D019310 Pseudolymphoma Phenobarbital 3.6412752131
MESH:D011596 Psychomotor Disorders Isotretinoin 5.0818769834
MESH:D011625 Pterygium Tretinoin 3.9516723453
MESH:D011629 Puberty, Precocious bisphenol A 3.9510548101
MESH:D011657 Pulmonary Eosinophilia alpha-Tocopherol 5.1414606601
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 7.0517322281 17365031 17975199 15814490
MESH:D011658 Pulmonary Fibrosis Paraquat 7.0516324872 17997886
MESH:D011658 Pulmonary Fibrosis troglitazone 7.0518162602
MESH:D015427 Reperfusion Injury Capsaicin 5.1718460982 19211983
MESH:D015427 Reperfusion Injury pirinixic acid 5.1719058328
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 6.6911700416 18379247
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 6.6911700416
MESH:D012127 Respiratory Distress Syndrome, Newborn Vitamin A 4.9616877224
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.1310835634
MESH:D012135 Respiratory Sounds Paraquat 3.2511874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.0318990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 15.983692021
MESH:D012162 Retinal Degeneration 9-cis-retinal 15.9817003450
MESH:D012162 Retinal Degeneration Fenretinide 15.9816303925
MESH:D012162 Retinal Degeneration Paraquat 15.9816458197
MESH:D012174 Retinitis Pigmentosa alpha-Tocopherol 3.6616849425
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.3216116481 16283617
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.4818045962
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.1616646077
MESH:D020426 Sciatic Neuropathy marker/mechanism 16782282
MESH:D012640 Seizures Lindane 6.727539098 15475178 12842176
MESH:D012640 Seizures Phenobarbital 6.723137016 11442880 16876388 4039156
MESH:D012640 Seizures Sulfonamides 6.7220420384
MESH:D003294 Seizures, Febrile Phenobarbital 3.986407741
MESH:D018805 Sepsis Zymosan 3.9411441115
MESH:D012871 Skin Diseases Vitamin A 3.0718709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 27.4710029692 19755658
MESH:D012878 Skin Neoplasms Fenretinide 27.4716467112
MESH:D012878 Skin Neoplasms Okadaic Acid 27.4712628509
MESH:D012878 Skin Neoplasms Retinoids 27.4717538947
MESH:D012878 Skin Neoplasms sodium arsenite 27.4719524636 18572023
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 27.478532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 27.4716192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 27.4712065085 18404319 8985016 8330346 11807781
MESH:D012878 Skin Neoplasms Tretinoin 27.4716467112
MESH:D013088 Spermatocele Ethinyl Estradiol 3.0916709447
MESH:D013119 Spinal Cord Injuries Progesterone 3.4516503802 15862959
MESH:D016135 Spinal Dysraphism sodium arsenite 3.1112854658
MESH:D013272 Stomach Diseases beta Carotene 12.4117638125
MESH:D013272 Stomach Diseases Dexamethasone 12.4115472012
MESH:D013272 Stomach Diseases Indomethacin 12.4116113693 16280098 10192188 16184426 18209964 17160473 17207306 18545984 17638125 15038085 10215738 10486359 15472012
MESH:D013274 Stomach Neoplasms arsenic trioxide 8.0717007042
MESH:D013274 Stomach Neoplasms Benzene 8.0712562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 8.0720155912 2093021
MESH:D013274 Stomach Neoplasms Docosahexaenoic Acids 8.0719015929
MESH:D013274 Stomach Neoplasms Indomethacin 8.0715609394
MESH:D013274 Stomach Neoplasms Tretinoin 8.0717261132
MESH:D013274 Stomach Neoplasms troglitazone 8.0715930296
MESH:D013276 Stomach Ulcer beta Carotene 7.9912500499
MESH:D013276 Stomach Ulcer Dexamethasone 7.9915138204
MESH:D013276 Stomach Ulcer Indomethacin 7.9917918041 16169175 18209962 16934674 17135157 14567935 17895592 17627676 18726076 18431645 16150113 12467913 10878458 16397915 11906479 18237397 12787963 11595431 10750652 18193104 1323529 15255614 16631530 15104355 10423059 17657623 18543354 18087811 17977527 11595415 17654042 12500499 16755016 12498302 11729361 18299717 11523592 15138204 11145282 16252198 18181030 12077510
MESH:D019966 Substance-Related Disorders bisphenol A 3.1616684133 16045194
MESH:D013705 Temporomandibular Joint Disorders Capsaicin 4.8717997062
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.4215821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.8411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.4315669648
MESH:D013953 Thymus Neoplasms Benzene 4.1210850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.0512697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 19.436582329 6587162 7505956 1399818 3712494
MESH:D013964 Thyroid Neoplasms arsenic trioxide 19.4319014326
MESH:D013964 Thyroid Neoplasms Indomethacin 19.4314736730 11352223 18791128
MESH:D013964 Thyroid Neoplasms Phenobarbital 19.431399818
MESH:D013964 Thyroid Neoplasms Retinoids 19.4316940797
MESH:D013964 Thyroid Neoplasms Tretinoin 19.4317045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 3.0416051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.1315213294
MESH:D014376 Tuberculosis Rifampin 6.4715236969 18397238
MESH:D014376 Tuberculosis Tretinoin 6.4716040207
MESH:D014456 Ulcer Indomethacin 4.0610574470 17380554
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 11.298074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 11.2912845720 11780464 20435036 12973940
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 11.2917053015
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 11.2916720286
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 11.2911723127 16452187 17306315 16712894
MESH:D014581 Urticaria Acetaminophen 2.2110982225
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 11.6716154183
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 11.6711813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 11.6716129372
MESH:D014591 Uterine Diseases bisphenol A 4.1514652134
MESH:D014594 Uterine Neoplasms Benzene 6.9312562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 6.9314692618
MESH:D014604 Uveal Neoplasms Tretinoin 3.7616752155
MESH:D014605 Uveitis Dexamethasone 9.461336536
MESH:D014605 Uveitis Zymosan 9.4611006244
MESH:D014652 Vascular Diseases sodium arsenite 3.5917056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.7412125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.7814671159 15869587
MESH:D014802 Vitamin A Deficiency Vitamin A 4.4916146918 16960172 16175781
MESH:D014820 Vitiligo Tretinoin 3.2616761959
MESH:D014839 Vomiting Indomethacin 3.9011897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.3915886252
MESH:D015430 Weight Gain Dietary Fats 3.0116723640
MESH:D009396 Wilms Tumor Tretinoin 3.2416287080
Pathway ID Pathway Name
KEGG:04920 Adipocytokine signaling pathway
KEGG:04976 Bile secretion
REACT:15380 Diabetes pathways
REACT:71 Gene Expression
KEGG:05160 Hepatitis C
REACT:22258 Metabolism of lipids and lipoproteins
KEGG:05223 Non-small cell lung cancer
KEGG:05200 Pathways in cancer
KEGG:03320 PPAR signaling pathway
KEGG:05222 Small cell lung cancer
KEGG:05216 Thyroid cancer
REACT:27166 Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA34890
    • Releated gene ID Related gene Name
    PA378NR1I2
    Releated disease ID Related disease Name
    PA443635Cardiovascular Diseases
    PA444552Hypertension
    Releated drug ID Related drug Name
    PA145007158torcetrapib
    PA451746tretinoin
    PA449905hydrocortisone
    PA450970pioglitazone
    PA451283rosiglitazone
    PA452631thiazolidinediones
    PA451776triglycerides
    PA451799troglitazone
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00210 other/unknown Adapalene Dermatologic Agents
    DB00307 agonist Bexarotene Anticarcinogenic Agents
    DB00459 agonist Acitretin Keratolytic Agents
    DB00523 agonist Alitretinoin Antineoplastic Agents;Keratolytic Agents
    DB00749 other Etodolac Anti-inflammatory Agents;Cyclooxygenase Inhibitors;Analgesics;Analgesics, Non-Narcotic;Antipyretics;Nonsteroidal Anti-inflammatory Agents (NSAIAs)
    DB00926 agonist Etretinate Keratolytic Agents
    DB07557 - (5BETA)-PREGNANE-3,20-DIONE
    DB07863 - 2-chloro-5-nitro-N-phenylbenzamide
    DB08063 - 1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE
    DB08402 - 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID
    DB08601 - tributylstannanyl
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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