AutismKB 2.0

Annotation Detail for S100A11


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Basic Information Top
Gene Symbol:S100A11 ( MLN70,S100C )
Gene Full Name: S100 calcium binding protein A11
Band: 1q21.3
Quick LinksEntrez ID:6282; OMIM: 603114; Uniprot ID:S10AB_HUMAN; ENSEMBL ID: ENSG00000163191; HGNC ID: 10488
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1934Cancer
2025Polyarthritis
2220Dermatitis
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in increased expression of S100A11 mRNAincreases expression 20406850
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of S100A11 mRNAincreases expression 18648102
C065250 4-hydroxy-equilenin 4-hydroxy-equilenin results in increased expression of S100A11 mRNAincreases expression 15135645
D000082 Acetaminophen Acetaminophen affects the expression of S100A11 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of S100A11 proteinaffects expression 20106945
D013196 Dihydrotestosterone Dihydrotestosterone results in increased expression of S100A11 proteinincreases expression 16751997
C006632 arsenic trioxide arsenic trioxide results in increased expression of S100A11 mRNAincreases expression 20458559
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of S100A11 mRNAincreases expression 20106945
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of S100A11 mRNAdecreases expression 20127859
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of S100A11 mRNAincreases expression 16239168
C055162 clopidogrel clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of S100A11 mRNA]decreases reaction|increases expression 19172522
C057862 cyanoginosin LR cyanoginosin LR results in increased expression of S100A11 mRNAincreases expression 17654400
D016572 Cyclosporine Cyclosporine results in increased expression of S100A11 mRNAincreases expression 20106945
C014347 decitabine decitabine affects the methylation of S100A11 geneaffects methylation 17579622
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of S100A11 mRNAincreases expression 19638242
D004958 Estradiol Estradiol results in increased expression of S100A11 mRNAincreases expression 20106945
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of S100A11 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of S100A11 mRNAaffects cotreatment|increases expression 17942748
D015073 2-Acetylaminofluorene 2-Acetylaminofluorene results in increased expression of S100A11 mRNAincreases expression 17317680
C056933 fumonisin B1 fumonisin B1 results in increased expression of S100A11 mRNAincreases expression 16221962
D008070 Lipopolysaccharides clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of S100A11 mRNA]decreases reaction|increases expression 19172522
D016685 Mitomycin S100A11 protein affects the susceptibility to Mitomycinaffects response to substance 16217747
C006253 pirinixic acid pirinixic acid results in decreased expression of S100A11 mRNAdecreases expression 17426115
C006253 pirinixic acid pirinixic acid results in increased expression of S100A11 mRNAincreases expression 16221962
D012643 Selenium Selenium results in increased expression of S100A11 mRNAincreases expression 19244175
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of S100A11 mRNAincreases expression 20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of S100A11 mRNAaffects cotreatment|increases expression 17942748
D014635 Valproic Acid Valproic Acid results in increased expression of S100A11 mRNAincreases expression 19101580
C025643 vinclozolin vinclozolin affects the expression of S100A11 mRNAaffects expression 19015723
D014810 Vitamin E Vitamin E results in increased expression of S100A11 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.6115322242 14514962 11752688
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 7.618875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.7419490988
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7317505938
MESH:D054058 Acute Coronary Syndrome clopidogrel 5.7919106084
MESH:D055371 Acute Lung Injury Lipopolysaccharides 8.3911850527 18653653
MESH:D055371 Acute Lung Injury pirinixic acid 8.3918653653
MESH:D000230 Adenocarcinoma arsenic trioxide 9.7019825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 9.7020127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 9.7011473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 9.7014692618
MESH:D000236 Adenoma 2-Acetylaminofluorene 15.0110737359
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 15.013712494
MESH:D000236 Adenoma Benzo(a)pyrene 15.016695378
MESH:D000236 Adenoma Diethylnitrosamine 15.0110737359 6695378
MESH:D002759 Adenoma, Bile Duct 2-Acetylaminofluorene 5.806705139
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 16.0519052882 17162532 19061943 17620307 16434500 18056438
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.0516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.0516835633
MESH:D000550 Amblyopia Valproic Acid 5.0217688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7611748828
MESH:D000799 Angioedema Acetaminophen 3.6310982225
MESH:D001008 Anxiety Disorders Valproic Acid 8.3117497229
MESH:D001008 Anxiety Disorders vinclozolin 8.3119015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.8719183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2611256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5415885639
MESH:D001321 Autistic Disorder Acetaminophen 1.8518445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8520603192 18177632 18558336 16609825 17507914 19232924 18316065 19460635 17157402 18940202 17688650 18396377 18985861 15238991 18775368
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.8111289319 1440618
MESH:D001714 Bipolar Disorder Valproic Acid 2.9717594078 20046352
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 14.1816206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 14.1819483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 14.1812125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5815340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.5815746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.588888407
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.2617474063 20146248
MESH:D001943 Breast Neoplasms decitabine 2.2619208741 18320071
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.2617474063
MESH:D001943 Breast Neoplasms Estradiol 2.2612948864 19861407 17289903 17261762 18497071 14630087 17018787 16675129
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.2620435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1311589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.2516111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 9.2416192424 18705752 15721981 16124888 16227642 16011737 16050911 16097048 15700767 15673190 10355542 3786805
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 9.2416050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6316835633
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 19.2316705839
MESH:D006528 Carcinoma, Hepatocellular 2-Acetylaminofluorene 19.2317761372 10737359 3084413 3581430 6705139
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 19.233581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 19.233084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 19.2321507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 19.2314691202 16217749 15553829 15073043 11135700
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 19.2318788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 19.2316935385 20101231 19919837 20524982 16502159 16830150 17173139 18393292 17055752 20007298 17138121 19335982 17978847 17162532 19208518 18785209 19171122 18691550 16328049 16681979 18665156 19394651 18788625 18506893 19701751 3581430 16569478 20432363 18971187 17761372 19539802 18494052 16878318 18978308 10672840 18056438 10737359 16779866 16288022 20084675 20214788 3084413 19418558 11831363 20514400 16807293 20727157 20512989 17428255 18210153 16540662 16698587 21159647 19519916 20935162 19383236 19107877 19822196 19052882
MESH:D006528 Carcinoma, Hepatocellular Estradiol 19.2316924424
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.6619014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.587296757
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9312490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.4720419170
MESH:D002294 Carcinoma, Squamous Cell decitabine 4.4719215824
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2518670907 16120746 18850075
MESH:D002318 Cardiovascular Diseases clopidogrel 4.4620180610
MESH:D002386 Cataract Acetaminophen 2.4610977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 19.566135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 19.567505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 19.5612371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 19.562727394 21159647 17174075 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 19.5618566989
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.6320734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.7419052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.7416835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 17.959022650 19486331
MESH:D002779 Cholestasis Cyclosporine 17.9519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 17.9517333356 16105132 16919318 17681005 17110522 11677210 15861022
MESH:D002779 Cholestasis pirinixic acid 17.9519176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0216354765 12621046 15668235 15340226 8697196
MESH:D003092 Colitis Selenium 3.5717936198
MESH:D003110 Colonic Neoplasms decitabine 2.3017616700
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.5320501625
MESH:D015179 Colorectal Neoplasms decitabine 2.5318981723
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8814669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.9812609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 5.2010525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 5.2010048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Valproic Acid 5.2016575769 17688650 8888407
MESH:D019465 Craniofacial Abnormalities Vitamin E 5.2019769572
MESH:D003456 Cryptorchidism vinclozolin 4.1414966744
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.8118551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9015213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.6111298694 8156756 8970840 18759878 2524372 12868966 14531868 11906362
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3318249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.303621924 2952479
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.0420387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.0417107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.2419279558
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 28.4118551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 28.417440962 9328219 6679447 6482804 18692083 1440618 11289319 18648102 18289764 9653073 8291058 9022650 16192314
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 28.4119164858 19370779 11461765 11421492 19420014 17906064 12540782 17522070 19923254 16781746 12594235 16393943 11739529 16109766 2444490 14725611 14550746 16177239 19416960 12958197 19739265 15968718 18713872 12392966 11743745 10915739 12153990 16485898 10663392 19085960 11529661 17562736 10774834 12705907 14986274 18071297 11287661 16081117 16227642 15619225 11834606
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 28.417120509 15968718 15027814 19085960 19336974 2869522 15998439 16177239 11566570 16227642 4309450 7440962 3732212 21278145 3786805 10915739 7179309 6884620 9327722 6623471 17522070 10092053
MESH:D056486 Drug-Induced Liver Injury cyanoginosin LR 28.4117654400
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 28.4119107877
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 28.4116221962
MESH:D056486 Drug-Induced Liver Injury Selenium 28.4115131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 28.4120420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 28.411733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.8919426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6111462148
MESH:D004421 Dystonia Valproic Acid 3.851851702
MESH:C538011 Eales disease Vitamin E 4.499068938
MESH:D004487 Edema pirinixic acid 5.9212083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.9212711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.6915322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 2.9912538720
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.9019294695
MESH:D016889 Endometrial Neoplasms Estradiol 2.8511473722 18566989 19148513
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.849294722 10568697
MESH:D019446 Endotoxemia Lipopolysaccharides 4.1915821434 17637181 15328337
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 3.9517275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 3.713922381 16628512
MESH:D004827 Epilepsy Valproic Acid 2.8320417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.416426943 7562514 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.097750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.853659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9016302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 6.893581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 6.8912903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 6.8916530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8611564622
MESH:D005234 Fatty Liver arsenic trioxide 34.0615073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 34.0615959796 17595544 16045604 61145 19224547 16239168 12795759 12631006
MESH:D005234 Fatty Liver Cyclosporine 34.0619224547
MESH:D005234 Fatty Liver Diethylnitrosamine 34.0620387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 34.0615345470
MESH:D005234 Fatty Liver pirinixic acid 34.0620131406 19236843
MESH:D005234 Fatty Liver Valproic Acid 34.0614986274 19224547
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2511858732
MESH:D005315 Fetal Diseases Valproic Acid 4.6716575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.938888407 18558336
MESH:D005334 Fever Lipopolysaccharides 3.8311852909 9205823
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.816705139
MESH:D005355 Fibrosis Carbon Tetrachloride 13.5118705752
MESH:D005355 Fibrosis Cyclosporine 13.5112168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 13.5120067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.0616904648
MESH:D005756 Gastritis Acetaminophen 3.4616983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.7216973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.0916417039
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.018708960
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.847505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3810696789
MESH:D006258 Head and Neck Neoplasms decitabine 3.3519215824
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 10.4720471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.4710048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 10.4716080930
MESH:D006333 Heart Failure pirinixic acid 6.5320558911
MESH:D006333 Heart Failure Selenium 6.5317162251
MESH:D006390 Hemangioendothelioma 2-Acetylaminofluorene 5.106705139
MESH:D006394 Hemangiosarcoma 2-Acetylaminofluorene 4.226705139
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2115720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.2016366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1511000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 8.556705139
MESH:D006505 Hepatitis Carbon Tetrachloride 8.5519900420 19110552
MESH:D006529 Hepatomegaly fumonisin B1 13.2916221962
MESH:D006529 Hepatomegaly pirinixic acid 13.2919772884 16221962 18467677 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 13.2915340226 16120746 12621046
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6316863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 4.8215709030
MESH:D019584 Hot Flashes Estradiol 9.3417088409
MESH:D019584 Hot Flashes Vitamin E 9.3414716179
MESH:D006849 Hydrocephalus Valproic Acid 4.6617688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8316354765 16959395 18606429 8697196 15340226
MESH:D006930 Hyperalgesia Acetaminophen 2.5416870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.3216899240
MESH:D006943 Hyperglycemia pirinixic acid 3.0020558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.7315034207
MESH:D006973 Hypertension Cyclosporine 4.6810903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.6818850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.8815338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6016569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2712013081
MESH:D007248 Infertility, Male decitabine 10.4317581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 10.4317937319
MESH:D007248 Infertility, Male vinclozolin 10.4316467254
MESH:D007249 Inflammation Diethylnitrosamine 7.7118785209
MESH:D007249 Inflammation Lipopolysaccharides 7.7117255318 12878042 17963957 9205823 17237260
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.7112878042 12200463
MESH:D007251 Influenza, Human Selenium 10.2516624496
MESH:D007251 Influenza, Human Vitamin E 10.2516624496
MESH:D007333 Insulin Resistance Estradiol 6.7516627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 6.7516306350
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.4317255318
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.819022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1516580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2315604871
MESH:D007674 Kidney Diseases Acetaminophen 13.4312587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 13.438314463 18776723 10903974
MESH:D007674 Kidney Diseases Estradiol 13.4315618244
MESH:D007674 Kidney Diseases Vitamin E 13.4312488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.7016518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 16.3416705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 16.346582329
MESH:D007680 Kidney Neoplasms Cyclosporine 16.3412371664
MESH:D007680 Kidney Neoplasms Estradiol 16.3415610895
MESH:D007938 Leukemia arsenic trioxide 6.1115070760
MESH:D007938 Leukemia decitabine 6.1118980019 19235587
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.6112560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.1016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.2714633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 8.9619077051
MESH:D007951 Leukemia, Myeloid decitabine 8.9618454857 17236224 19117987
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 5.9216467208 16968895 19850784 20471514 17050201
MESH:D015470 Leukemia, Myeloid, Acute decitabine 5.9218704418 19387464 18460780 18206229 19010910 17679729
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 5.9216294345 17596541
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.2518055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.0815748426 15622746 11468182 15213294 17649720 16891316 19075265 12679006 16112521 17869043 9834237 17217047 16331271 19225113 17712046 12018890 15336539 11161223 17107899 16966277 19642359 16823087 12712474 19035177 16330433
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.1516882451
MESH:D007970 Leukopenia Lipopolysaccharides 4.4915821434
MESH:D007984 Leydig Cell Tumor vinclozolin 4.5216417039
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.2317157831 17174718 16943688 21278145 11408273 17334410 16221502 16239168 11903743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.2318665156 18407596 18522880 20032147 19638242
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.0715034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 8.3818187930 17976157 18418968 17922224 17805973 16011737 17640975 18339082 12445421 12445418 18472094 15057751 18156304 16033810 12632514 15362042 14748882 14512876 12958196 15996030 18277467 16097048 18376398 15123356 18251166 14716496 12546737 15052691 17766677 10355542 12667390 18205269 17708605 17900296 12898905 18705752 15876570 16116963 18210741 13678700 18395914 18166357 17525996 15370692 16192424 18006644 17631135 15925388 18472332 12666154 17714472 11481614 12632512 20821823 15730626 18054572 15673190 18429990 16136751 17698563 15338365 14620537 15931870 15650968 15818738 16015684 16248980 12741479 12649538 18263696 18412020 14716833 17761835 16027843 17869086 17565644 17557913 18317297 17481882 15959796 12586293 12389079 18481824 18279442 17823541 14724832 18420326 15893842 17721639 18395095 12609069 16638106 17944888
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 8.3814716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 8.3812878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 8.3815474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 8.3812878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 8.3816169303
MESH:D008107 Liver Diseases Acetaminophen 6.1419460945 11587558 16611625 12587719 12969438 19014921 19784758 16610002
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.1415830285 16246199 16964402 17285989 15720792
MESH:D008107 Liver Diseases Diethylnitrosamine 6.1417034775
MESH:D017093 Liver Failure Carbon Tetrachloride 3.9615123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.8017185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.8016899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 32.787678174
MESH:D008113 Liver Neoplasms 2-Acetylaminofluorene 32.7816273603 10737359 10672840 14678523 11376686 18001218
MESH:D008113 Liver Neoplasms Aflatoxin B1 32.789163691 15890375 2125692 18177683
MESH:D008113 Liver Neoplasms arsenic trioxide 32.7814682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 32.7821137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 32.7819294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 32.7820583210 20101389 20118626 20137499 19996281 19254457 19256749 19294768 16942905 19642983 10737359 12112319 15885732 19690152 21167192 2862719 20452335 12771043 9163691 15175105 20501860 2422723 21278145 18648771 21047994 19551842 18754104 19090486 19833225 19499222 19255062 21071580 19426721 18977376 19073162 19638242 19427195 18644402 19850985 20434301 20405173 20492335 19812893 18978307
MESH:D008113 Liver Neoplasms Mitomycin 32.7815113037
MESH:D008113 Liver Neoplasms pirinixic acid 32.7820007298 16377806 15890375
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 32.7816984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 31.062876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental 2-Acetylaminofluorene 31.06534488 6150874 1399818
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 31.06598648 3712494 6587162 1399818
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 31.068603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 31.0620377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 31.0612014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 31.0616267830 18164116 19519916 19126423 19009564 18093689 19539802 18282651 9362446 18308698 2563599 17942915 19004024 18775883 18544905 16842330 18079962 18253720 3124819 17854601 21159647 17174075
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 31.0612151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.1915213294
MESH:D008171 Lung Diseases Vitamin E 3.0416863852
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.0517228818
MESH:D055370 Lung Injury Lipopolysaccharides 3.8021114838
MESH:D008175 Lung Neoplasms 2-Acetylaminofluorene 10.2911376686
MESH:D008175 Lung Neoplasms Aflatoxin B1 10.2914755239
MESH:D008175 Lung Neoplasms arsenic trioxide 10.2919825857 11798837
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 10.2920464547 20135361 18569708 18520028 20869020 6695378 17053015 20064080 18816296
MESH:D008175 Lung Neoplasms Diethylnitrosamine 10.2920970405 21163286 20512841 6695378
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 10.2919555203 11884234
MESH:D008175 Lung Neoplasms Vitamin E 10.2911062179
MESH:D008223 Lymphoma decitabine 3.2719470736
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 5.5811807958 16891317 11408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Selenium 5.5815318939
MESH:D020149 Manganese Poisoning Estradiol 4.2719453300
MESH:D008545 Melanoma decitabine 2.2216505122 17785578
MESH:D008546 Melanoma, Experimental Acetaminophen 3.3619513568
MESH:D008654 Mesothelioma Selenium 2.7115107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5816801185
MESH:D008881 Migraine Disorders Valproic Acid 3.0418803445 18765137
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.0316381670
MESH:D009101 Multiple Myeloma arsenic trioxide 6.8919417148 11468182 19549372 15949261 14977855
MESH:D009101 Multiple Myeloma decitabine 6.8918172295
MESH:D009135 Muscular Diseases pirinixic acid 3.3016239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.848888407
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.4618349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 11.6616882451 16105982
MESH:D009190 Myelodysplastic Syndromes decitabine 11.6619157545 16882708 18608210 19010910
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 11.6617596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.0619151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8512213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.7216810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.7216411023
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.6518551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.7616624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 9.193581430
MESH:D009362 Neoplasm Metastasis clopidogrel 9.1911875746
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 9.199029167 3581430
MESH:D009369 Neoplasms Benzo(a)pyrene 7.6311141357
MESH:D009369 Neoplasms decitabine 7.6317925555 19116145 19470736
MESH:D009369 Neoplasms pirinixic acid 7.6317405874
MESH:D009389 Neovascularization, Pathologic Estradiol 3.5217289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2317954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1118481113 19348381
MESH:D009421 Nervous System Malformations Estradiol 8.7911399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.7914600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 11.356679447
MESH:D009436 Neural Tube Defects arsenic trioxide 11.3510525206
MESH:D009436 Neural Tube Defects Valproic Acid 11.358888407 16359493
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.6218514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.6220387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9020387270
MESH:D009765 Obesity pirinixic acid 1.7620558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.2716049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 8.276482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.813988306
MESH:D010051 Ovarian Neoplasms arsenic trioxide 7.5212452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms decitabine 7.5219259094 19331143
MESH:D010051 Ovarian Neoplasms Estradiol 7.5219401270
MESH:D010146 Pain Acetaminophen 2.2316870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 11.7615580305
MESH:D010190 Pancreatic Neoplasms decitabine 11.7619294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 11.7616540662
MESH:D010190 Pancreatic Neoplasms Mitomycin 11.7615113037
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4911578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.287296757
MESH:D010235 Paraganglioma arsenic trioxide 3.9719927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0412520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.266228378
MESH:D010954 Plasmacytoma Selenium 4.6815087411
MESH:D011014 Pneumonia Lipopolysaccharides 4.3411605937 12224865
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3618163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.3612371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.362563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 15.0111222880 11896295 11118676 11399792
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 15.0120603192
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 15.0119015723 18042343 18220299
MESH:D055728 Primary Myelofibrosis decitabine 4.5217616702
MESH:D011469 Prostatic Diseases vinclozolin 4.7218220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.6920887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.0919131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.0917292933
MESH:D011471 Prostatic Neoplasms Estradiol 2.0916740699
MESH:D011471 Prostatic Neoplasms Vitamin E 2.0915084515
MESH:D011472 Prostatitis vinclozolin 4.7218629315
MESH:D011537 Pruritus Ethinyl Estradiol 3.1016919318 15861022
MESH:D019310 Pseudolymphoma Valproic Acid 4.3311422049 12752131
MESH:D011565 Psoriasis Cyclosporine 2.1616882103
MESH:D015427 Reperfusion Injury pirinixic acid 2.2919058328
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.5910835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6418990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.223692021
MESH:D012170 Retinal Vein Occlusion clopidogrel 5.9219371211
MESH:D012208 Rhabdomyosarcoma decitabine 10.3219155313
MESH:D012208 Rhabdomyosarcoma Valproic Acid 10.3219155313
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.7616646077
MESH:D012559 Schizophrenia Valproic Acid 2.0415737665 19110320
MESH:D012640 Seizures 2,6-dinitrotoluene 5.4818551238
MESH:D012640 Seizures Valproic Acid 5.4811044598 17978042 3137016 14763951 15475178 16876388 11738929 1511512
MESH:D012871 Skin Diseases Vitamin E 2.3918709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.1519755658 10029692
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.1516192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.7316709447
MESH:D016135 Spinal Dysraphism Valproic Acid 3.6219490988
MESH:D013226 Status Epilepticus Valproic Acid 4.3312833885
MESH:D013274 Stomach Neoplasms arsenic trioxide 4.5417007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 4.542093021 20155912
MESH:D013274 Stomach Neoplasms decitabine 4.5419037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 4.5418456281
MESH:D020521 Stroke Vitamin E 3.3616517955
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.9815821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6912697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 15.816582329 3712494 1399818 6587162 7505956
MESH:D013964 Thyroid Neoplasms arsenic trioxide 15.8119014326
MESH:D013964 Thyroid Neoplasms decitabine 15.8117967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 15.817505956
MESH:D013978 Tibial Fractures Estradiol 4.4719048282
MESH:D016171 Torsades de Pointes arsenic trioxide 3.7515213294
MESH:D014178 Translocation, Genetic Valproic Acid 5.0217262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.313119515
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 18.8216049721
MESH:D001749 Urinary Bladder Neoplasms 2-Acetylaminofluorene 18.821399818 15289314 15867355
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 18.828074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 18.8220435036 12845720 12973940 11780464
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 18.8217053015
MESH:D001749 Urinary Bladder Neoplasms decitabine 18.8217616700 19087683
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.448888407
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.1110091137
MESH:D014581 Urticaria Acetaminophen 2.7810982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1014692618
MESH:D014604 Uveal Neoplasms decitabine 4.7017785578
MESH:D014605 Uveitis Cyclosporine 3.771336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3812125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3514671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0415886252
MESH:D014985 Xerophthalmia Cyclosporine 4.2317120751
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB02482 - Phosphonothreonine Indicators and Reagents
No data
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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