AutismKB 2.0

Annotation Detail for SCD


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SCD ( FADS5,MSTP008,SCD1,SCDOS )
Gene Full Name: stearoyl-CoA desaturase (delta-9-desaturase)
Band: 10q24.31
Quick LinksEntrez ID:6319; OMIM: 604031; Uniprot ID:ACOD_HUMAN; ENSEMBL ID: ENSG00000099194; HGNC ID: 10571
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-5996oleate biosynthesis II (animals)
Pathway IDPathway Name
hsa03320PPAR signaling pathway
hsa01040Biosynthesis of unsaturated fatty acids
No data
No data
No data
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Related Diseases/Disorders Top
No data
Desease IDDesease Name
1831Prostate cancer
1842Sickle cell disease
1856Obesity
1904Diabetes mellitus
1944Breast cancer
2097Hyperlipidemia
No data
No data
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C063002 2,3-dimethoxy-1,4-naphthoquinone 2,3-dimethoxy-1,4-naphthoquinone results in decreased expression of SCD mRNAdecreases expression 17547211
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [FGF7 protein results in increased expression of SCD protein]decreases reaction|increases expression 16162944
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in increased expression of SCD mRNAincreases expression 20406850
D000082 Acetaminophen Acetaminophen results in decreased expression of SCD mRNAdecreases expression 17202758
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of SCD proteinaffects expression 20106945
D000639 Amitriptyline Amitriptyline results in increased expression of SCD mRNAincreases expression 16324787
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SCD mRNAaffects expression 16483693
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [FGF7 protein results in increased expression of SCD protein]decreases reaction|increases expression 16162944
D000965 Antimony Antimony results in decreased expression of SCD mRNAdecreases expression 17547211
D000966 Antimony Potassium Tartrate Antimony Potassium Tartrate results in decreased expression of SCD mRNAdecreases expression 17547211
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of SCD mRNAdecreases expression 20106945
C095105 bexarotene bexarotene results in increased expression of SCD mRNAincreases expression 17178900
D001629 Bezafibrate Bezafibrate results in increased expression of SCD mRNAincreases expression 17118139
D016642 Bupropion Bupropion results in increased expression of SCD mRNAincreases expression 16324787
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of SCD mRNAdecreases expression 15336504
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of SCD mRNAdecreases expression 17202758
D002784 Cholesterol Cholesterol inhibits the reaction [FGF7 protein results in increased expression of SCD mRNA]decreases reaction|increases expression 16162944
D015283 Citalopram Citalopram results in increased expression of SCD mRNAincreases expression 16324787
D002997 Clomipramine Clomipramine results in increased expression of SCD mRNAincreases expression 16324787
D003024 Clozapine Clozapine results in increased expression of SCD mRNAincreases expression 17052361
16027736
D016572 Cyclosporine Cyclosporine results in decreased expression of SCD mRNAdecreases expression 20106945
D002117 Calcitriol Calcitriol results in decreased expression of SCD mRNAdecreases expression 12798352
D004128 Dimethylnitrosamine Dimethylnitrosamine results in decreased expression of SCD mRNAdecreases expression 17547211
C045651 epigallocatechin gallate epigallocatechin gallate results in decreased expression of SCD mRNAdecreases expression 16988119
D004958 Estradiol Estradiol results in decreased expression of SCD mRNAdecreases expression 15757668
D011345 Fenofibrate Fenofibrate results in increased expression of SCD mRNAincreases expression 17118139
D005395 Fish Oils Fish Oils results in decreased expression of SCD mRNAdecreases expression 15654130
D005472 Fluorouracil Fluorouracil results in decreased expression of SCD mRNAdecreases expression 17982676
D005472 Fluorouracil Fluorouracil results in increased expression of SCD mRNAincreases expression 17039268
D005472 Fluorouracil SCD protein affects the susceptibility to Fluorouracilaffects response to substance 16217747
D005472 Fluorouracil TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of SCD mRNA]decreases expression|decreases reaction 17982676
D005473 Fluoxetine Fluoxetine results in increased expression of SCD mRNAincreases expression 16324787
D005632 Fructose Fructose results in increased expression of SCD mRNAincreases expression 18063403
C056507 gemcitabine gemcitabine results in increased expression of SCD mRNAincreases expression 17039268
D019833 Genistein Genistein results in decreased expression of SCD mRNAdecreases expression 15257099
D019833 Genistein Genistein results in increased expression of SCD mRNAincreases expression 15378649
18847459
D005947 Glucose Glucose results in increased expression of SCD mRNAincreases expression 16790840
C010176 halofuginone halofuginone results in increased expression of SCD mRNAincreases expression 17180598
D006220 Haloperidol Haloperidol results in increased expression of SCD mRNAincreases expression 16027736
D007099 Imipramine Imipramine results in increased expression of SCD mRNAincreases expression 16324787
D007213 Indomethacin Indomethacin results in increased expression of SCD mRNAincreases expression 18299717
D007529 Isoflavones Isoflavones affects the expression of SCD mRNAaffects expression 16365062
D007529 Isoflavones Isoflavones results in increased expression of SCD mRNAincreases expression 17374662
C095104 LG 100268 LG 100268 results in increased expression of SCD mRNAincreases expression 17178900
C008493 methylselenic acid methylselenic acid affects the expression of SCD mRNAaffects expression 14617803
C035133 mirtazapine mirtazapine results in increased expression of SCD mRNAincreases expression 16324787
D008942 Mitoxantrone SCD protein affects the susceptibility to Mitoxantroneaffects response to substance 16217747
C452423 N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine results in increased expression of SCD mRNAincreases expression 16052530
C006253 pirinixic acid pirinixic acid results in increased expression of SCD mRNAincreases expression 15654130
D011374 Progesterone Progesterone results in increased expression of SCD mRNAincreases expression 18070364
C009159 rapeseed oil rapeseed oil affects the expression of SCD mRNAaffects expression 16177195
C116926 rofecoxib rofecoxib results in increased expression of SCD mRNAincreases expression 17070997
C004648 testosterone enanthate testosterone enanthate affects the expression of SCD mRNAaffects expression 17440010
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of SCD mRNAdecreases expression 20106945
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SCD mRNAincreases expression 16704738
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SCD mRNAincreases expression 15644576
D013752 Tetracycline Tetracycline results in decreased expression of SCD mRNAdecreases expression 17202758
C423915 TO-901317 TO-901317 results in increased expression of SCD mRNAincreases expression 15548517
C066340 tolcapone tolcapone binds to SCD proteinaffects binding 19783845
D019772 Topotecan SCD protein affects the susceptibility to Topotecanaffects response to substance 16217747
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.3015322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.0118287403
MESH:D055371 Acute Lung Injury pirinixic acid 2.6118653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 14.8120127859 20464547
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 14.8116033868
MESH:D000230 Adenocarcinoma Estradiol 14.8111473722
MESH:D000230 Adenocarcinoma Fluorouracil 14.8117638652
MESH:D000230 Adenocarcinoma Genistein 14.8111473722
MESH:D000230 Adenocarcinoma Indomethacin 14.8116537180
MESH:D000236 Adenoma Benzo(a)pyrene 9.316695378
MESH:D000236 Adenoma Dimethylnitrosamine 9.3119555203
MESH:D000236 Adenoma Indomethacin 9.3111497255
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.0616434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.0616835633
MESH:D000380 Agranulocytosis Clozapine 4.5112649775 14617031 16160616
MESH:D017109 Akathisia, Drug-Induced tolcapone 5.7211080934
MESH:D000505 Alopecia Isoflavones 4.2717569567
MESH:D016301 Alveolar Bone Loss Indomethacin 4.8017225004
MESH:D000544 Alzheimer Disease Indomethacin 4.2117627676 15579461
MESH:D000544 Alzheimer Disease tolcapone 4.2120150427
MESH:D000740 Anemia Fluorouracil 7.0717963324 16511603 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.0711748828
MESH:D000799 Angioedema Acetaminophen 3.2810982225
MESH:D001008 Anxiety Disorders Citalopram 8.5218083778
MESH:D001008 Anxiety Disorders Fluoxetine 8.5218083778
MESH:D001014 Aortic Aneurysm Indomethacin 4.3210231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 9.9119183758
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 9.9110388637
MESH:D018771 Arthralgia Indomethacin 4.602160914
MESH:D001169 Arthritis, Experimental rofecoxib 3.9916690336
MESH:D001172 Arthritis, Rheumatoid Indomethacin 2.6711248219
MESH:D001249 Asthma epigallocatechin gallate 3.2016516891
MESH:D050197 Atherosclerosis Cholesterol 3.9016632123
MESH:D001321 Autistic Disorder Acetaminophen 3.2318445737
MESH:D001321 Autistic Disorder Citalopram 3.2319232924 18775368
MESH:D001321 Autistic Disorder Fluoxetine 3.2319232924 18775368
MESH:D001321 Autistic Disorder Haloperidol 3.2318080171 19368416
MESH:D001321 Autistic Disorder mirtazapine 3.2316648008
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 4.5219761891
MESH:D001477 Bartter Syndrome Indomethacin 4.4410684365
MESH:D001778 Blood Coagulation Disorders pirinixic acid 7.1119483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 7.1112125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.2215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.3915746008
MESH:D001929 Brain Edema Indomethacin 4.4611481608
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.7717868700
MESH:D001930 Brain Injuries Progesterone 3.7215665606 15845082 15380490
MESH:D002545 Brain Ischemia Indomethacin 3.8712524144
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 7.3517474063 20146248
MESH:D001943 Breast Neoplasms bexarotene 7.3516818667 16344269
MESH:D001943 Breast Neoplasms Calcitriol 7.3511237771
MESH:D001943 Breast Neoplasms Estradiol 7.3512948864 16675129 17018787 17261762 19861407 14630087 18497071 17289903
MESH:D001943 Breast Neoplasms Fluorouracil 7.3516595493 16110121 19217205 15136595 18357371 18608205 16557594
MESH:D001943 Breast Neoplasms gemcitabine 7.3518382427 17039268
MESH:D001943 Breast Neoplasms Genistein 7.3516873071 17200150 16541309
MESH:D001943 Breast Neoplasms Indomethacin 7.3517401462
MESH:D001943 Breast Neoplasms LG 100268 7.3516818667
MESH:D001943 Breast Neoplasms Progesterone 7.3516175315 17614352 15562024
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 7.3520435547
MESH:D001991 Bronchitis Antimony 5.568768112
MESH:D002056 Burns Indomethacin 4.1610459503
MESH:D002100 Cachexia Indomethacin 4.4515625704 11239499 15141370 16537180
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.9116111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.2418705752 16097048 10355542 16124888 16050911 16011737 3786805 15673190 15721981 15700767 16227642 16192424
MESH:D002276 Carcinoid Tumor Fluorouracil 4.1016051944
MESH:D002277 Carcinoma Dimethylnitrosamine 11.4219555203
MESH:D002277 Carcinoma Fluorouracil 11.4217121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 11.4216835633
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 17.4916705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 17.493084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 17.4921507988 12619106 12907637
MESH:D006528 Carcinoma, Hepatocellular anthra(1,9-cd)pyrazol-6(2H)-one 17.4919418558
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 17.4918788625
MESH:D006528 Carcinoma, Hepatocellular Estradiol 17.4916924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 17.4917088986 17971768 16332177 18930000 17045692 16799960
MESH:D006528 Carcinoma, Hepatocellular Genistein 17.4916924424
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 17.4916391822
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.1711053908
MESH:D018276 Carcinoma, Medullary Indomethacin 4.7914736730 18791128 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.0116247446
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 5.7818695887
MESH:D002292 Carcinoma, Renal Cell Indomethacin 5.7817341418
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 12.2320419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 12.2311237771
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 12.2316033868
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 12.2316757204 18986760 16280240 17066447
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 12.2315482327 12636206
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.0416120746 18850075 18670907
MESH:D002311 Cardiomyopathy, Dilated Antimony 3.7010334427
MESH:D002318 Cardiovascular Diseases Genistein 6.4416332659
MESH:D002318 Cardiovascular Diseases Isoflavones 6.4417689850
MESH:D002375 Catalepsy Haloperidol 4.3615215559 1977408
MESH:D002386 Cataract Acetaminophen 2.2410977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 8.856135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 8.8512371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 8.8518566989
MESH:D002659 Child Development Disorders, Pervasive Citalopram 4.3315782081
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.6916835633
MESH:D002764 Cholecystitis Indomethacin 4.6011181007
MESH:D002779 Cholestasis Cyclosporine 6.3619486331
MESH:D002779 Cholestasis pirinixic acid 6.3619176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.858697196 15668235 16354765 15340226 12621046
MESH:D003072 Cognition Disorders Clozapine 4.4217123785
MESH:D003110 Colonic Neoplasms Fluorouracil 7.2417725105 17287894 15001691 17016597 16510598 16340194 18772588 17172411 17018589 17169374
MESH:D003110 Colonic Neoplasms Genistein 7.2417182828
MESH:D003110 Colonic Neoplasms Indomethacin 7.2415936596 15786552 15625704 15963497 11260862 15637740
MESH:D003110 Colonic Neoplasms rofecoxib 7.2412902858
MESH:D015179 Colorectal Neoplasms Fluorouracil 3.2715289873 15148649 18288408 17401013 18949393 16524972 14970324 16391804 18448328 18802399 17255274 20501625 18509181 16282729 17016601 17695437 16331619 16303861 17594712 18383874 17454858 17094418
MESH:D015179 Colorectal Neoplasms Indomethacin 3.2718059344 12606626 11197048 17054584
MESH:D015179 Colorectal Neoplasms Isoflavones 3.2717116718
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.5917141729 14669216
MESH:D003327 Coronary Disease Fructose 4.1018504504
MESH:D018352 Coronavirus Infections Indomethacin 5.1517302372
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2320055451 15322242 10048152
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.4718551238
MESH:D007644 Darier Disease Fluorouracil 4.2316733453
MESH:D016757 Death, Sudden, Cardiac Haloperidol 4.3320210726
MESH:D003704 Dementia Haloperidol 4.0811575062
MESH:D003866 Depressive Disorder Amitriptyline 35.1318083778 15014590
MESH:D003866 Depressive Disorder Bupropion 35.1315014590
MESH:D003866 Depressive Disorder Citalopram 35.1315014590
MESH:D003866 Depressive Disorder Clomipramine 35.1318083778
MESH:D003866 Depressive Disorder Fluoxetine 35.1315014590
MESH:D003866 Depressive Disorder Imipramine 35.1320305041
MESH:D003866 Depressive Disorder mirtazapine 35.1318083778
MESH:D003866 Depressive Disorder tolcapone 35.137768276 11224284
MESH:D003865 Depressive Disorder, Major tolcapone 4.4310440460
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.1418249437
MESH:D003921 Diabetes Mellitus, Experimental Fructose 4.0418603373
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 11.8216402076
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 11.8216988119
MESH:D003924 Diabetes Mellitus, Type 2 Fructose 11.8218603373
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 11.8216647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 11.8217107852
MESH:D003928 Diabetic Nephropathies Estradiol 2.9419279558
MESH:D003929 Diabetic Neuropathies Progesterone 3.9517187935
MESH:D003967 Diarrhea Indomethacin 3.287907874 7237001
MESH:D006970 Disorders of Excessive Somnolence Clozapine 4.9915331141
MESH:D004283 Dog Diseases Antimony 5.1012019027
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 15.5618551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 15.5615619225 19420014 18713872 10915739 14550746 19164858 2444490 15968718 11743745 11461765 19739265 18071297 10663392 19085960 11739529 19416960 12153990 17906064 19923254 11834606 11529661 16227642 14725611 16109766 16781746 16177239 12540782 16081117 16485898 12705907 12594235 11287661 12392966 16393943 14986274 19370779 10774834 17562736 12958197 17522070 11421492
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 15.566623471 7440962 15998439 10915739 11566570 16227642 6884620 21278145 7179309 2869522 15027814 16177239 3732212 19085960 3786805 9327722 15968718 10092053 4309450 19336974 17522070 7120509
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 15.568172417
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 15.5620420201
MESH:D056486 Drug-Induced Liver Injury Tetracycline 15.5617522070
MESH:D056486 Drug-Induced Liver Injury tolcapone 15.5619783845 16604736
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.5319426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.3411462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.5918446180 16133044 18043480 16326151 12774134 17190690
MESH:D004381 Duodenal Ulcer Indomethacin 3.6116699067 17045617 11535926 11991626 17151854 11595431 17329845 10671773 17202747 17351913 11595415
MESH:D004409 Dyskinesia, Drug-Induced tolcapone 4.8311455177
MESH:D050171 Dyslipidemias Clozapine 7.8516402076
MESH:D050171 Dyslipidemias Fenofibrate 7.8516707586
MESH:D004487 Edema Amitriptyline 25.0612798668
MESH:D004487 Edema Clomipramine 25.0612798668
MESH:D004487 Edema Fluoxetine 25.0612798668
MESH:D004487 Edema Imipramine 25.0612798668
MESH:D004487 Edema Indomethacin 25.0616100529 7990266 7907874 8273558 8985016 10653021 19703484
MESH:D004487 Edema pirinixic acid 25.0612083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 25.0612711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.3318230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 7.5615138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 7.5617692515
MESH:D004714 Endometrial Hyperplasia Genistein 4.0316402032
MESH:D016889 Endometrial Neoplasms Estradiol 10.3911473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Fenofibrate 10.3916569247
MESH:D016889 Endometrial Neoplasms Genistein 10.3911473722
MESH:D004715 Endometriosis Indomethacin 17.9115652904
MESH:D004715 Endometriosis Progesterone 17.9116134523
MESH:D004715 Endometriosis rofecoxib 17.9115652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 17.9110568697 9294722
MESH:D019446 Endotoxemia Indomethacin 3.9518509659
MESH:D004751 Enteritis Indomethacin 4.1810567023 17763956 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.4417980183
MESH:D004802 Eosinophilia Indomethacin 3.5211298111
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 8.9616530937
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 8.9617016578
MESH:D004938 Esophageal Neoplasms Fluorouracil 8.9617638652 15173087 16481741 16785472 16337965
MESH:D004938 Esophageal Neoplasms Indomethacin 8.9611005569
MESH:D054908 Extensively Drug-Resistant Tuberculosis tolcapone 5.3819578428
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.5911564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 24.3061145 12795759 15959796 12631006 16239168 16045604 17595544 19224547
MESH:D005234 Fatty Liver Cyclosporine 24.3019224547
MESH:D005234 Fatty Liver Fish Oils 24.3018620774
MESH:D005234 Fatty Liver Fructose 24.3018395287 18641190 19196556
MESH:D005234 Fatty Liver pirinixic acid 24.3020131406 19236843
MESH:D005234 Fatty Liver Tetracycline 24.3016917069 19224547
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.9111858732
MESH:D005329 Fetishism (Psychiatric) mirtazapine 6.7518439117
MESH:D005334 Fever Indomethacin 3.6410431976 11852909 17627676
MESH:D005354 Fibrosarcoma Indomethacin 4.3410962813
MESH:D005355 Fibrosis Carbon Tetrachloride 22.0318705752
MESH:D005355 Fibrosis Cyclosporine 22.0312168785 12639820
MESH:D005355 Fibrosis Fructose 22.0318504504
MESH:D005355 Fibrosis Indomethacin 22.0317994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 22.0320067830
MESH:D005499 Folliculitis Indomethacin 4.6011298111
MESH:D005756 Gastritis Acetaminophen 9.2616983495
MESH:D005756 Gastritis Indomethacin 9.2615046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.668708960
MESH:D005909 Glioblastoma Genistein 6.1516598420
MESH:D005909 Glioblastoma Indomethacin 6.1512870263
MESH:D005910 Glioma Fluorouracil 5.4116145905
MESH:D005910 Glioma Indomethacin 5.4118371953 16487511
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.8411849393
MESH:D018149 Glucose Intolerance Fructose 4.8119165636
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.0310696789
MESH:D006073 Gout Indomethacin 4.7911248219
MESH:D006258 Head and Neck Neoplasms Fluorouracil 6.7018337622 15162350 15102660
MESH:D006258 Head and Neck Neoplasms Indomethacin 6.7015482327
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 5.3820471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.3811294989 10048152
MESH:D006331 Heart Diseases Mitoxantrone 3.7616019553
MESH:D006333 Heart Failure pirinixic acid 2.1820558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.8615720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.8411000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.0715633222
MESH:D006505 Hepatitis Carbon Tetrachloride 3.0719900420 19110552
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.1515135802
MESH:D006529 Hepatomegaly pirinixic acid 6.4719176532 18467677 19772884 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 6.4712621046 15340226 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.4615709030
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.1817440010
MESH:D019584 Hot Flashes Estradiol 14.0817088409
MESH:D019584 Hot Flashes Fluoxetine 14.0814716179
MESH:D019584 Hot Flashes Isoflavones 14.0814716179 17290160
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.4818606429 16354765 16959395 15340226 8697196
MESH:D006930 Hyperalgesia Acetaminophen 6.3616870215
MESH:D006930 Hyperalgesia Indomethacin 6.3612727271
MESH:D034321 Hyperamylasemia Indomethacin 5.1517883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.9716899240
MESH:D006937 Hypercholesterolemia Cholesterol 4.4816933029
MESH:D006940 Hyperemia Indomethacin 4.4512524144
MESH:D006943 Hyperglycemia pirinixic acid 2.7020558911
MESH:D006946 Hyperinsulinism Fructose 4.4315752949 19008412 18360027 18563319 14757778
MESH:D006948 Hyperkinesis Clozapine 4.3516046005
MESH:D006949 Hyperlipidemias Fish Oils 12.8015752949
MESH:D006949 Hyperlipidemias Fructose 12.8015752949
MESH:D006949 Hyperlipidemias Indomethacin 12.8017546600
MESH:D006965 Hyperplasia halofuginone 4.7011874485
MESH:D006968 Hypersensitivity, Delayed Fish Oils 4.9411484837
MESH:D006973 Hypertension Cyclosporine 7.2510903974
MESH:D006973 Hypertension Fructose 7.2514568997 14573337 14633139 16843071 19008412
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.2518850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.5415338365
MESH:D015228 Hypertriglyceridemia Fructose 4.5919799862 19342510
MESH:D007077 Ileal Diseases Indomethacin 4.4610574470 18306037
MESH:D007079 Ileitis Indomethacin 4.7910651667 10647630 16133968
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.8016133044
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.8615869954
MESH:D007249 Inflammation Amitriptyline 19.4012798668
MESH:D007249 Inflammation Clomipramine 19.4012798668
MESH:D007249 Inflammation Fluoxetine 19.4012798668
MESH:D007249 Inflammation Imipramine 19.4012798668
MESH:D007249 Inflammation Indomethacin 19.407812673 12568917 3291741
MESH:D007249 Inflammation Progesterone 19.4015869954
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 19.4012200463 12878042
MESH:D007333 Insulin Resistance Estradiol 10.2416627594 16393666
MESH:D007333 Insulin Resistance Fructose 10.2414757778 14633139 17133782 18563319 19799862 18981581 18057795 19586609 19342510 19008412 14573337
MESH:D007333 Insulin Resistance pirinixic acid 10.2416306350
MESH:D007410 Intestinal Diseases Indomethacin 8.5517994277 15831440 11713966 17329856 18236018 10210152 11686837 11855677 15610444
MESH:D007410 Intestinal Diseases rofecoxib 8.5515831440
MESH:D007417 Intestinal Polyps rofecoxib 4.8511245490
MESH:D019586 Intracranial Hypertension Indomethacin 4.8015241188
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.8416580747
MESH:D007579 Jejunal Diseases Indomethacin 4.4610574470 18306037 16133968
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.8715604871
MESH:D007674 Kidney Diseases Acetaminophen 11.6112587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 11.618314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 11.6115618244
MESH:D007674 Kidney Diseases Indomethacin 11.6117190690
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 14.0216705839
MESH:D007680 Kidney Neoplasms Cyclosporine 14.0212371664
MESH:D007680 Kidney Neoplasms Estradiol 14.0215610895
MESH:D007680 Kidney Neoplasms Fluorouracil 14.0216985049
MESH:D007859 Learning Disorders Cholesterol 4.5617134702
MESH:D007896 Leishmaniasis Antimony 4.3415220340 21063981 12019027 10953559 21182181
MESH:D016773 Leishmaniasis, Cutaneous Antimony 7.4311475954 8889330 19141829
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 7.4310320625 12228301 11703811
MESH:D007897 Leishmaniasis, Mucocutaneous Antimony 4.937854095 11370249 10651420 9643325 10881086
MESH:D007898 Leishmaniasis, Visceral Antimony 7.3020495762 7554475 8142506 7854095 1899875 11105143 7875148
MESH:D007898 Leishmaniasis, Visceral Antimony Potassium Tartrate 7.3012707265
MESH:D007938 Leukemia 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 5.7812970779
MESH:D007938 Leukemia Genistein 5.7817468513 18980019
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Mitoxantrone 3.5318172266
MESH:D007948 Leukemia, Monocytic, Acute anthra(1,9-cd)pyrazol-6(2H)-one 4.8216972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.5010785260 16572323 15631656
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 2.5318360721
MESH:D015473 Leukemia, Promyelocytic, Acute Antimony Potassium Tartrate 4.149834237
MESH:D007964 Leukocytosis Indomethacin 4.8016537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.1517980183
MESH:D008064 Lipidoses Amitriptyline 25.3315342952 17567588
MESH:D008064 Lipidoses Citalopram 25.3317567588
MESH:D008064 Lipidoses Clomipramine 25.3315342952 17567588
MESH:D008064 Lipidoses Clozapine 25.3317567588
MESH:D008064 Lipidoses Fluoxetine 25.3317567588 15342952
MESH:D008064 Lipidoses Imipramine 25.3317567588 15342952
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.1511479899
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 5.9516221502 11903743 17174718 11408273 21278145 17157831 16239168 16943688 17334410
MESH:D008103 Liver Cirrhosis halofuginone 5.9517180598
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 18.5918418968 16638106 14748882 18187930 15996030 16248980 16033810 15338365 18472332 15730626 17976157 12546737 15876570 16192424 16116963 18277467 17698563 12898905 14716496 18376398 17481882 17631135 16011737 12649538 14716833 12632514 18420326 15931870 12445418 17761835 18054572 17557913 12445421 17708605 17640975 17714472 15959796 15673190 17823541 12632512 18395095 17805973 12741479 18395914 15370692 12958196 12609069 18210741 15362042 18251166 18705752 13678700 15925388 17766677 16015684 17525996 11481614 17922224 14512876 15818738 15650968 18412020 18166357 18279442 18481824 15057751 18429990 10355542 18006644 18156304 17721639 15052691 17565644 17944888 18205269 17869086 16027843 15893842 18317297 14620537 12389079 14724832 12666154 18263696 18472094 16097048 20821823 17900296 18339082 12667390 16136751 15123356 12586293
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 18.5917465448 15086199 14726149 14643895 15099470 16009107 17719030 18637143 15479170 18210741 18364076 17640959 15763062 17881167 15492853 15591649 17036385 17196135 17348192 15504291 15733078 15298665 15842777 18567088 12918455 16169303 15067225 16544323 17201889 15744066 15366600 18629640 17666798 15138612 18371158 18239293 14568256 16570917 15339415 14659978 15369754 17534399 15942678 15577212 18095165 15723089 18672772 15793283 15081153 12925901 16627068 15571005 14709902 17203207 18237412 15798949 15383259 16603200 16270385 17724770 16042886 15161499 17432682 17198567 15864749
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 18.5917481882
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 18.5914716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Fenofibrate 18.5915474484
MESH:D008106 Liver Cirrhosis, Experimental Genistein 18.5917823541
MESH:D008106 Liver Cirrhosis, Experimental halofuginone 18.5916489207 18458672 14739098 11172339 12175628
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 18.5918194892
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 18.5915474484
MESH:D008106 Liver Cirrhosis, Experimental rofecoxib 18.5917565644
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 18.5912878042
MESH:D008107 Liver Diseases Acetaminophen 3.3219784758 16610002 12969438 16611625 19014921 12587719 19460945 11587558
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.3215720792 16964402 17285989 16246199 15830285
MESH:D017093 Liver Failure Carbon Tetrachloride 3.6215123358
MESH:D017114 Liver Failure, Acute Acetaminophen 13.4616871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 13.4616899240 14706259
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 13.4617457977
MESH:D008113 Liver Neoplasms marker/mechanism 12419843
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 25.247678174
MESH:D008113 Liver Neoplasms Aflatoxin B1 25.2415890375 18177683 9163691 2125692
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 25.2421137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 25.2419294768
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 25.243113478 15890375
MESH:D008113 Liver Neoplasms Fenofibrate 25.2418978307
MESH:D008113 Liver Neoplasms Fluorouracil 25.2416603448 18383874 15113037 17045692
MESH:D008113 Liver Neoplasms pirinixic acid 25.2420007298 15890375 16377806
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 25.2416984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 18.632876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 18.638603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 18.6315583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 18.631848544 15603536 6150874
MESH:D008114 Liver Neoplasms, Experimental Fenofibrate 18.6318775883 18253720
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 18.6312151625
MESH:D008175 Lung Neoplasms Aflatoxin B1 9.2714755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 9.2720464547 20064080 18569708 20135361 18816296 6695378 18520028 17053015 20869020
MESH:D008175 Lung Neoplasms bexarotene 9.2717849452
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 9.2719555203 16061637 11884234
MESH:D008175 Lung Neoplasms Fluorouracil 9.2715246190
MESH:D008175 Lung Neoplasms Indomethacin 9.2711053908 11497255 16537180
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 9.2719555203 11884234
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.2315086387
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.6011161223
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 14.9019196723 15591091 19196722
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 14.9016891317 17203775 11807958 11408345
MESH:D008325 Mammary Neoplasms, Experimental Genistein 14.9012929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental LG 100268 14.9012374698
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 14.9017203775 11408345
MESH:D020149 Manganese Poisoning Estradiol 3.9219453300
MESH:D008545 Melanoma epigallocatechin gallate 3.7217992120 11746506
MESH:D008545 Melanoma Glucose 3.7214993021
MESH:D008546 Melanoma, Experimental Acetaminophen 3.0219513568
MESH:D001523 Mental Disorders Amitriptyline 33.2416856516
MESH:D001523 Mental Disorders Citalopram 33.2416856516
MESH:D001523 Mental Disorders Clomipramine 33.2416856516
MESH:D001523 Mental Disorders Clozapine 33.2416856516
MESH:D001523 Mental Disorders Fluoxetine 33.2416856516
MESH:D001523 Mental Disorders Haloperidol 33.2416856516
MESH:D001523 Mental Disorders Imipramine 33.2416856516
MESH:D001523 Mental Disorders mirtazapine 33.2416856516
MESH:D024821 Metabolic Syndrome X Clozapine 8.5219142101
MESH:D024821 Metabolic Syndrome X Fructose 8.5219165636 17098227 16815490 18497449 17261469
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.2216801185
MESH:D008881 Migraine Disorders Amitriptyline 6.9518803445
MESH:D008881 Migraine Disorders Indomethacin 6.9511903285
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 11.9116381670
MESH:D009062 Mouth Neoplasms Fluorouracil 11.9118986760 16757204
MESH:D009062 Mouth Neoplasms Indomethacin 11.9112636206
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 4.9317962980
MESH:D009135 Muscular Diseases Bezafibrate 8.9316239165
MESH:D009135 Muscular Diseases pirinixic acid 8.9316239165
MESH:D009203 Myocardial Infarction Genistein 4.8017141266
MESH:D009203 Myocardial Infarction pirinixic acid 4.8019151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.5712213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 11.6616810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 11.6617141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 11.6616411023
MESH:D009207 Myoclonus Fluoxetine 5.328041377
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.317678174 18551238
MESH:D009362 Neoplasm Metastasis Indomethacin 2.9216537180 11053908 11239499
MESH:D009369 Neoplasms Benzo(a)pyrene 9.3911141357
MESH:D009369 Neoplasms Fluorouracil 9.3918600527 18239605 16928823
MESH:D009369 Neoplasms Mitoxantrone 9.3916640825
MESH:D009369 Neoplasms pirinixic acid 9.3917405874
MESH:D009374 Neoplasms, Experimental Indomethacin 3.6010663608 15625704
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 4.2219196722
MESH:D009389 Neovascularization, Pathologic Estradiol 3.1817289903
MESH:D009395 Nephritis, Interstitial Tetracycline 4.229884423
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.8717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.8118481113 19348381
MESH:D009421 Nervous System Malformations Estradiol 13.3111399458 16427766
MESH:D009421 Nervous System Malformations Genistein 13.3116427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 13.3114600291
MESH:D009447 Neuroblastoma Topotecan 3.5415176712
MESH:D019636 Neurodegenerative Diseases Acetaminophen 6.8818514411
MESH:D019636 Neurodegenerative Diseases Indomethacin 6.8812349958
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.0516436463
MESH:D052556 Niemann-Pick Disease, Type C Cholesterol 5.1620557099 9802331
MESH:D009765 Obesity Clozapine 6.6018515891 19142110
MESH:D009765 Obesity Fructose 6.6017707055 18585860
MESH:D009765 Obesity pirinixic acid 6.6020558911
MESH:D009771 Obsessive-Compulsive Disorder Fluoxetine 4.9420418887
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.606374098
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 2.9516049721
MESH:D010003 Osteoarthritis Indomethacin 6.957009135
MESH:D010003 Osteoarthritis rofecoxib 6.9516690336
MESH:D010024 Osteoporosis Genistein 6.3919401787
MESH:D010024 Osteoporosis Isoflavones 6.3916562857
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.5716169203
MESH:D010051 Ovarian Neoplasms 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 9.6116211241
MESH:D010051 Ovarian Neoplasms Estradiol 9.6119401270
MESH:D010051 Ovarian Neoplasms Genistein 9.6119005980
MESH:D010051 Ovarian Neoplasms Progesterone 9.6116525653 17393432
MESH:D010146 Pain Acetaminophen 20.6516870215
MESH:D010146 Pain Amitriptyline 20.6512798668
MESH:D010146 Pain Clomipramine 20.6512798668
MESH:D010146 Pain Fluoxetine 20.6512798668
MESH:D010146 Pain Imipramine 20.6512798668
MESH:D010146 Pain Indomethacin 20.6517627676 17440234 3291741 13679232
MESH:D010149 Pain, Postoperative Indomethacin 9.6812538197 18702446
MESH:D010149 Pain, Postoperative rofecoxib 9.6816678543 18165598
MESH:D010190 Pancreatic Neoplasms Fluorouracil 4.9619003803 16929163 15113037 16500647
MESH:D010190 Pancreatic Neoplasms gemcitabine 4.9611504793 17440100 18992248 16929163 18383843
MESH:D010195 Pancreatitis Indomethacin 3.4215028970 17883296
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.1516537180
MESH:D010300 Parkinson Disease tolcapone 3.379305320 11432539 9333106 20334432 9754991 11746615 11793426 8739811 8635184 18328768 9708959 19783845 20216409 19578428 16758261 11586115 1977408 10651109 9591521 7566641 17089403
MESH:D020734 Parkinsonian Disorders Indomethacin 3.6412349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.1511903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.6812520081
MESH:D010391 Pemphigoid, Bullous Tetracycline 4.8611026799
MESH:D010409 Penile Diseases Antimony 5.199643325
MESH:D010437 Peptic Ulcer Indomethacin 4.5911148446
MESH:D010493 Pericarditis Antimony 5.5620465667
MESH:D010518 Periodontitis Indomethacin 4.3517225004
MESH:D020774 Pick Disease of the Brain Fluoxetine 5.458041377
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.0318163543
MESH:D011230 Precancerous Conditions Cyclosporine 2.7512371664
MESH:D047928 Premature Birth Indomethacin 4.5817000239
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.6411399792 11222880 11896295 11118676
MESH:D017096 Prion Diseases Tetracycline 4.8610903871
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.2215572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.3820887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.0017292933
MESH:D011471 Prostatic Neoplasms Calcitriol 2.0016289102 15754350 16644109 18247401 12479363
MESH:D011471 Prostatic Neoplasms Estradiol 2.0016740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.0019082440 18626508
MESH:D011471 Prostatic Neoplasms Genistein 2.0016925846 15378649 15256057
MESH:D011471 Prostatic Neoplasms Isoflavones 2.0017374662 17571952 16365062 17219775
MESH:D011471 Prostatic Neoplasms methylselenic acid 2.0016205645
MESH:D011507 Proteinuria Indomethacin 3.6511849393
MESH:D011565 Psoriasis Cyclosporine 2.0116882103
MESH:D011595 Psychomotor Agitation Haloperidol 4.4111575062
MESH:D011618 Psychotic Disorders Clozapine 7.7915331141
MESH:D011618 Psychotic Disorders Haloperidol 7.7911575062
MESH:D012004 Rectal Neoplasms Fluorouracil 3.5418722050 15538739 18286688 16160472
MESH:D015427 Reperfusion Injury pirinixic acid 2.0919058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.3118990726
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.6318045962
MESH:D012559 Schizophrenia Clozapine 3.7420107430 18806925 18855531 20452607 20168265 20521320 20580759 11151749 17667964 17123785 16141801 19369910 17726453 20521326 11763009
MESH:D012559 Schizophrenia Haloperidol 3.7419369910 20107430 18513383 1830565
MESH:D012640 Seizures 2,6-dinitrotoluene 2.1718551238
MESH:D020230 Serotonin Syndrome Fluoxetine 5.338704074
MESH:D012871 Skin Diseases halofuginone 3.3511874485
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 11.1919755658 10029692
MESH:D012878 Skin Neoplasms Glucose 11.1914993021
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 11.198532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 11.1916192470
MESH:D012892 Sleep Deprivation Imipramine 5.6419798453
MESH:D007319 Sleep Initiation and Maintenance Disorders Amitriptyline 4.8915341891
MESH:D013119 Spinal Cord Injuries Progesterone 3.7215862959 16503802
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.7012587719
MESH:D013272 Stomach Diseases Indomethacin 3.8716113693 16184426 18209964 17207306 10192188 17160473 16280098 15038085 10486359 10215738 17638125 15472012 18545984
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 4.172093021 20155912
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 4.1716033868
MESH:D013274 Stomach Neoplasms Fluorouracil 4.1716951190 16424979 19084572 18567086 17522103 18396642 15786421 19015929 17498489 17172411
MESH:D013274 Stomach Neoplasms Indomethacin 4.1715609394
MESH:D013276 Stomach Ulcer Indomethacin 3.1117135157 15138204 17654042 12077510 10423059 18431645 17895592 18237397 18209962 12498302 17918041 16755016 18543354 16252198 16631530 11523592 11906479 18193104 17977527 17627676 1323529 14567935 10878458 17657623 12787963 16169175 18726076 12467913 16150113 16934674 16397915 11595431 11145282 15255614 15104355 11595415 18087811 10750652 18181030 11729361 18299717 12500499
MESH:D017180 Tachycardia, Ventricular Haloperidol 4.1820210726
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.3312697716
MESH:D013964 Thyroid Neoplasms Indomethacin 6.6418791128 14736730 11352223
MESH:D013964 Thyroid Neoplasms N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine 6.6416940797
MESH:D013978 Tibial Fractures Estradiol 4.1219048282
OMIM:188890 TOBACCO ADDICTION, SUSCEPTIBILITY TO Bupropion 5.4916785264
MESH:D014029 Tobacco Use Disorder Bupropion 6.0820388087
MESH:D014062 Tongue Neoplasms Fluorouracil 3.5016280240
MESH:D014352 Trypanosomiasis Antimony 5.3615220340
MESH:D018088 Tuberculosis, Multidrug-Resistant tolcapone 5.3819578428
MESH:D014456 Ulcer Indomethacin 4.3410574470 17380554
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 4.1516049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 4.1517053015
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 3.7610091137
MESH:D014581 Urticaria Acetaminophen 2.4710982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 3.3916803524
MESH:D014605 Uveitis Cyclosporine 3.421336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.0312125929
MESH:D014820 Vitiligo tolcapone 4.6610573327
MESH:D014839 Vomiting Indomethacin 4.1811897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.6815886252
MESH:D015430 Weight Gain Clozapine 4.0020564506 20107430 16402076 17502770 16141801 20521320
MESH:D015431 Weight Loss Clozapine 4.5217933447
MESH:D014985 Xerophthalmia Cyclosporine 3.8717120751
Pathway ID Pathway Name
KEGG:01040 Biosynthesis of unsaturated fatty acids
KEGG:03320 PPAR signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA34984
    • No data
    Releated disease ID Related disease Name
    PA447216Schizophrenia
    Releated drug ID Related drug Name
    PA449061clozapine
    PA449841haloperidol
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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