Annotation Detail for SCNN1D Basic Information
Top Gene Symbol: SCNN1D ( ENaCd,ENaCdelta,MGC149710,MGC149711,SCNED,dNaCh ) Gene Full Name: sodium channel, nonvoltage-gated 1, delta Band: 1p36.33 Quick Links Entrez ID:6339 ; OMIM: 601328 ; Uniprot ID:SCNND_HUMAN ; ENSEMBL ID: ENSG00000162572 ; HGNC ID: 10601
Relate to Another Database:
SFARIGene ;
denovo-db
Desease ID Desease Name 1770 Melanoma
Chemical ID
Chemical Name
Interaction
Interaction Action
Publication C055656 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP
8-((4-chlorophenyl)thio)cyclic-3',5'-GMP results in increased activity of [SCNN1A binds to SCNN1B binds to SCNN1G binds to SCNN1D] affects binding|increases activity 19359370 C090860 8-(4-chlorophenylthio)guanosine 3',5'-cyclic monophosphorothioate
8-(4-chlorophenylthio)guanosine 3',5'-cyclic monophosphorothioate results in increased activity of [SCNN1A binds to SCNN1B binds to SCNN1G binds to SCNN1D] affects binding|increases activity 19359370 D000584 Amiloride
Amiloride results in decreased activity of [SCNN1A binds to SCNN1B binds to SCNN1G binds to SCNN1D] affects binding|decreases activity 19359370 D012964 Sodium
[SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein binds to SCNN1D protein] which results in increased transport of Sodium affects binding|increases transport 19359370
Disease ID
Disease Name
Direct Evidence
Inference Chemical Name
Inference Score
Publication MESH:D002295
Carcinoma, Transitional Cell
Amiloride
5.47 14644129 MESH:D003092
Colitis
Amiloride
5.67 12065299 MESH:D006130
Growth Disorders
Amiloride
4.99 19703807 MESH:D006973
Hypertension
Amiloride
3.99 19344079 18524855 15174897 MESH:D020514
Hypokalemic Periodic Paralysis
Amiloride
6.48 19822448 MESH:D007249
Inflammation
Amiloride
3.99 17237260 MESH:D056929
Liddle Syndrome
Amiloride
6.53 19344079 MESH:D009361
Neoplasm Invasiveness
Amiloride
5.81 14644129
Drugbank ID
Action
Drug Name
Description DB00384 antagonist
Riva-Zide 50/25mg Tablets
Diuretics;Potassium-sparing Diuretics DB00594 blocker
Riva-Amilzide 5/50 mg
Sodium channel blockers;Diuretics
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