AutismKB 2.0

Annotation Detail for SCP2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SCP2 ( DKFZp686C12188,DKFZp686D11188,NLTP,NSL-TP,SCP-2,SCP-CHI,SCP-X,SCPX )
Gene Full Name: sterol carrier protein 2
Band: 1p32.3
Quick LinksEntrez ID:6342; OMIM: 184755; Uniprot ID:NLTP_HUMAN; ENSEMBL ID: ENSG00000116171; HGNC ID: 10606
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-6061bile acid biosynthesis, neutral pathway
Pathway IDPathway Name
hsa03320PPAR signaling pathway
hsa00120Primary bile acid biosynthesis
hsa01100Metabolic pathways
hsa04146Peroxisome
Pathway IDPathway Name
Metabolism of lipids and lipoproteins
No data
No data
Pathway IDPathway Name
500820Beta-oxidation of pristanoyl-CoA
500828Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Related Diseases/Disorders Top
Desease IDDesease Name
H00407Peroxisomal beta-oxidation enzyme deficiency
Peroxisomal diseases
Genetic disorders
No data
No data
No data
Desease Name
Leukoencephalopathy with dystonia and motor neuropathy
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of SCP2 mRNAincreases expression 18648102
D000082 Acetaminophen [Dietary Carbohydrates co-treated with Acetaminophen] results in decreased expression of SCP2 mRNAaffects cotreatment|decreases expression 17093179
D000082 Acetaminophen Acetaminophen affects the expression of SCP2 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of SCP2 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SCP2 mRNAaffects expression 16483693
C095105 bexarotene bexarotene results in decreased expression of SCP2 mRNAdecreases expression 16648578
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of SCP2 mRNAdecreases expression 15336504
D002211 Capsaicin Capsaicin results in decreased expression of SCP2 mRNAdecreases expression 18533110
D002713 Chlorine Chlorine results in decreased expression of SCP2 mRNAdecreases expression 18636392
D002713 Chlorine [Ozone co-treated with Chlorine] affects the expression of SCP2 mRNAaffects cotreatment|affects expression 18636392
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SCP2 mRNAaffects cotreatment|affects expression 17602206
D016572 Cyclosporine Cyclosporine results in decreased expression of SCP2 mRNAdecreases expression 20106945
D004040 Dietary Carbohydrates [Dietary Carbohydrates co-treated with Acetaminophen] results in decreased expression of SCP2 mRNAaffects cotreatment|decreases expression 17093179
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SCP2 mRNAaffects cotreatment|affects expression 17602206
D000431 Ethanol [Fish Oils co-treated with Ethanol] results in increased expression of SCP2 mRNAaffects cotreatment|increases expression 17347304
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of SCP2 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SCP2 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SCP2 mRNAaffects cotreatment|increases expression 17942748
D005395 Fish Oils [Fish Oils co-treated with Ethanol] results in increased expression of SCP2 mRNAaffects cotreatment|increases expression 17347304
C029424 hydrazine hydrazine results in decreased expression of SCP2 mRNAdecreases expression 15370871
D007657 Ketone Bodies Ketone Bodies results in increased expression of SCP2 mRNAincreases expression 16807920
C011890 kojic acid kojic acid results in decreased expression of SCP2 mRNAdecreases expression 16595896
D015741 Metribolone Metribolone affects the localization of SCP2 proteinaffects localization 17440980
D010126 Ozone [Ozone co-treated with Chlorine] affects the expression of SCP2 mRNAaffects cotreatment|affects expression 18636392
D010126 Ozone Ozone results in decreased expression of SCP2 mRNAdecreases expression 16716893
D010795 Phthalic Acids Phthalic Acids results in decreased expression of SCP2 mRNAdecreases expression 15728792
C006253 pirinixic acid pirinixic acid results in increased expression of SCP2 mRNAincreases expression 17426115
C006253 pirinixic acid pirinixic acid results in increased expression of SCP2 mRNAincreases expression 16940010
D013629 Tamoxifen Tamoxifen affects the expression of SCP2 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SCP2 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SCP2 mRNAincreases expression 17942748
D014501 Uranium Uranium affects the expression of SCP2 mRNAaffects expression 15672453
C005460 uranyl acetate uranyl acetate affects the expression of SCP2 mRNAaffects expression 15672453
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.3414745880
MESH:D000014 Abnormalities, Drug-Induced Capsaicin 13.1818926900
MESH:D000014 Abnormalities, Drug-Induced Ethanol 13.1817676605 18926900
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 13.1814514962 15322242 11752688
MESH:D000138 Acidosis Ammonium Chloride 9.7718287403
MESH:D000138 Acidosis Ethanol 9.7711192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7317505938
MESH:D058186 Acute Kidney Injury Capsaicin 4.3518460982
MESH:D055371 Acute Lung Injury Chlorine 8.5020601635
MESH:D055371 Acute Lung Injury pirinixic acid 8.5018653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.7614692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 6.273712494
MESH:D000236 Adenoma Diethylnitrosamine 6.276695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 16.0517162532 19061943 16434500 19052882 18056438 17620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.0516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.0516835633
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 5.1115451039 15451040
MESH:D000505 Alopecia Capsaicin 4.5617569567
MESH:D000544 Alzheimer Disease Ozone 2.3915513908
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7611748828
MESH:D000799 Angioedema Acetaminophen 3.6310982225
MESH:D000853 Anophthalmos Ethanol 4.6115513904
MESH:D001008 Anxiety Disorders Ethanol 3.8411141031
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2611256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5415885639
MESH:D001172 Arthritis, Rheumatoid Ozone 2.5115570426
MESH:D001249 Asthma Ozone 2.5817854713 16373670
MESH:D001289 Attention Deficit Disorder with Hyperactivity Phthalic Acids 4.2220106747
MESH:D001321 Autistic Disorder Acetaminophen 1.4418445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.811440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.1419483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.1412125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5815340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6315746008
MESH:D001919 Bradycardia Capsaicin 4.8518207255
MESH:D002545 Brain Ischemia Capsaicin 4.7619211983
MESH:D001943 Breast Neoplasms bexarotene 1.9416818667 16344269
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.9417474063
MESH:D001943 Breast Neoplasms Tamoxifen 1.9415565566 20065188 19103187 18629630 19487384 17893378 19221464 18855134 17049068 18815881 19115204 15668708 16873071 18997820 20859285 17242785 19189212 18351453 17440819 16273361 20005174 19244106 19410462 20135344 18425577 11161223 19200415 19066611 19189210 19084267 21152245 19011961 20390343 19059307 17261762 16202921 19288272 19289846 20544844 16818667 18984771 18821012 21138602 19155303 19142967
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9420435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.5116777450 18417511 15516495 17626835 19059883 14754758 18315731
MESH:D002056 Burns Ethanol 4.4416374292
MESH:D002100 Cachexia Ozone 4.5316183385
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6316835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.3019066611
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 10.933581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 10.933084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 10.9321507988 12619106 12907637
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 10.9317055752 18665156 10672840 11831363 20727157 17428255 18494052 16779866 20512989 16830150 19919837 16681979 18393292 18691550 20214788 17138121 16878318 19539802 17761372 20935162 17162532 20524982 16569478 18056438 20514400 16288022 16935385 19418558 19208518 3084413 18978308 19171122 19383236 17978847 16328049 21159647 19107877 16698587 18788625 19052882 16502159 19519916 20101231 19701751 17173139 20432363 20007298 20084675 18210153 3581430 19335982 19394651 18971187 18506893 19822196 18785209 10737359 16807293 16540662
MESH:D006528 Carcinoma, Hepatocellular Ethanol 10.9315289165 15763234 18788625
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 10.9316924424
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.1616247446
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.587296757
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.4317572228
MESH:D006332 Cardiomegaly Ethanol 6.4619332462
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.4618850075 18670907 16120746
MESH:D002386 Cataract Acetaminophen 2.4610977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 10.327505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.3212371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 10.3221159647 2727394 17174075 7505956
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.7419052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.7416835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 17.9519486331 9022650
MESH:D002779 Cholestasis Cyclosporine 17.9519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 17.9515861022 17333356 16105132 16919318 17110522 11677210 17681005
MESH:D002779 Cholestasis pirinixic acid 17.9519176532
MESH:D002971 Cleft Lip Ethanol 3.4815513904
MESH:D002972 Cleft Palate Ethanol 5.6615513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.6616354765 12621046 15668235 8697196 15340226
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8817141729 14669216
MESH:D003371 Cough Capsaicin 4.9610350223
MESH:D019465 Craniofacial Abnormalities Ethanol 2.5715451039 11198716 19302082 11873399 10194807 15513904 15451040
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.5715322242 20055451 10048152
MESH:D003711 Demyelinating Diseases Tamoxifen 4.1519031437
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.6112868966 8970840 2524372 11298694 18759878 11906362 14531868 8156756
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3318249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.302952479 3621924
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.0420387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.0417107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.3019279558
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 11.3318289764 8291058 9328219 7440962 1440618 16192314 6679447 9022650 9653073 6482804 18648102 11289319 18692083
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.3317562736 2444490 16485898 11421492 11739529 15619225 11529661 17906064 11743745 14725611 10663392 10774834 14550746 16227642 12705907 11461765 16393943 19416960 10915739 17522070 12153990 11834606 19370779 19085960 12392966 19420014 18071297 19923254 11287661 19739265 12540782 15968718 18713872 16177239 16781746 16081117 12594235 19164858 14986274 16109766 12958197
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 11.3319107877
MESH:D056486 Drug-Induced Liver Injury Ethanol 11.3311566570
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.3320420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.8919426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6111462148
MESH:D004381 Duodenal Ulcer Capsaicin 4.4911535926 10671773
MESH:D004417 Dyspnea Chlorine 4.4120016425
MESH:D004421 Dystonia marker/mechanism
MESH:D004487 Edema pirinixic acid 5.9212083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.9212711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.6918230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.2812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.2819031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 2.9119155303 20544844 17893378 16202921
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.849294722 10568697
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9016302075
MESH:D004935 Esophageal Diseases Capsaicin 5.4919566590
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 4.453581430
MESH:D004938 Esophageal Neoplasms Ethanol 4.4516704527
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8611564622
MESH:D005234 Fatty Liver Cyclosporine 34.0719224547
MESH:D005234 Fatty Liver Diethylnitrosamine 34.0721071580 20387270
MESH:D005234 Fatty Liver Ethanol 34.0718620774 19236843 16409862
MESH:D005234 Fatty Liver Ethinyl Estradiol 34.0715345470
MESH:D005234 Fatty Liver Fish Oils 34.0718620774
MESH:D005234 Fatty Liver pirinixic acid 34.0719236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 34.0719224547 14986274
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.4517920746
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1116709447
MESH:D005310 Fetal Alcohol Syndrome Ethanol 5.0910194807 15513904 16946407 15451040
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2511858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.816705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.3214745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.9719069698
MESH:D005355 Fibrosis Cyclosporine 7.7912168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 7.7920067830
MESH:D005739 Gas Poisoning Chlorine 4.8020016425
MESH:D005756 Gastritis Acetaminophen 10.4216983495
MESH:D005756 Gastritis Ethanol 10.4215046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.018708960
MESH:D005909 Glioblastoma Capsaicin 3.9818405923
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.847505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3810696789
MESH:D006356 Heartburn Capsaicin 5.4919566590
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2211294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.4120558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2115720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1511000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.316705139
MESH:D006529 Hepatomegaly pirinixic acid 7.5718467677 19176532 16221962 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.5715340226 16120746 12621046
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.838697196 18606429 16354765 15340226 16959395
MESH:D006930 Hyperalgesia Acetaminophen 12.2716870215
MESH:D006930 Hyperalgesia Capsaicin 12.2717434803 17043245
MESH:D006930 Hyperalgesia Ethanol 12.2718783367
MESH:D006943 Hyperglycemia pirinixic acid 3.0020558911
MESH:D006949 Hyperlipidemias Fish Oils 4.5615752949
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.7315034207
MESH:D006968 Hypersensitivity, Delayed Fish Oils 5.2911484837
MESH:D006973 Hypertension Cyclosporine 4.6810903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.6818670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6016945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.3517937319
MESH:D007249 Inflammation Capsaicin 11.1016956363
MESH:D007249 Inflammation Diethylnitrosamine 11.1018785209
MESH:D007249 Inflammation Tamoxifen 11.1019457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.1012200463 12878042
MESH:D007333 Insulin Resistance pirinixic acid 2.5016306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.818074119 9022650
MESH:D007569 Jaw Abnormalities Ethanol 9.4915513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.4916580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2315604871
MESH:D007674 Kidney Diseases Acetaminophen 5.4012587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 5.408314463 10903974 18776723
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 11.396582329
MESH:D007680 Kidney Neoplasms Cyclosporine 11.3912371664
MESH:D007680 Kidney Neoplasms Tamoxifen 11.3918625569
MESH:D007859 Learning Disorders Ethanol 4.0015451040
MESH:D056784 Leukoencephalopathies marker/mechanism
MESH:D017880 Limb Deformities, Congenital Ethanol 3.6717676605
MESH:D008064 Lipidoses Tamoxifen 3.0115342952 17567588
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.4419638242 18665156 20032147 18407596 18522880
MESH:D008103 Liver Cirrhosis Ethanol 6.4415289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.8918295389
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.0715034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 4.7318166357
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.7315474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.7318564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.7312878042
MESH:D008107 Liver Diseases Acetaminophen 6.3016610002 19784758 12587719 16611625 11587558 19460945 12969438 19014921
MESH:D008107 Liver Diseases Capsaicin 6.3016956363
MESH:D008107 Liver Diseases Diethylnitrosamine 6.3017034775
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.4417207112 17347304
MESH:D017114 Liver Failure, Acute Acetaminophen 3.0516871587 17185352
MESH:D008113 Liver Neoplasms Aflatoxin B1 16.9418177683 2125692 9163691 15890375
MESH:D008113 Liver Neoplasms Clofibric Acid 16.9417602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 16.9419850985 21278145 20434301 20501860 20452335 9163691 15885732 12771043 19254457 19996281 15175105 12112319 20101389 19638242 21167192 19833225 19812893 19073162 18644402 19551842 18977376 19255062 19294768 20583210 18648771 18978307 19426721 20118626 19256749 18754104 19690152 16942905 2862719 20405173 19499222 19642983 20492335 10737359 21071580 19427195 21047994 2422723 19090486 20137499
MESH:D008113 Liver Neoplasms pirinixic acid 16.9416377806 15890375 20007298
MESH:D008113 Liver Neoplasms Tamoxifen 16.9416684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 16.9416984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 17.27598648 1399818 3712494 6587162
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 17.278603461
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 17.2719126423 19539802 2563599 18775883 19004024 17854601 18164116 18544905 9362446 18079962 18282651 16842330 18093689 18308698 17942915 19009564 3124819 16267830 17174075 21159647 19519916 18253720
MESH:D008114 Liver Neoplasms, Experimental kojic acid 17.2718544905
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 17.2712151625
MESH:D008171 Lung Diseases Ozone 3.2419066396 8266340
MESH:D055370 Lung Injury Ozone 3.6420417186
MESH:D008175 Lung Neoplasms Aflatoxin B1 8.2114755239
MESH:D008175 Lung Neoplasms bexarotene 8.2117849452
MESH:D008175 Lung Neoplasms Diethylnitrosamine 8.2120970405 6695378 21163286 20512841
MESH:D008175 Lung Neoplasms Ozone 8.218597069 7614698
MESH:D008175 Lung Neoplasms Tamoxifen 8.2118625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.2119555203 11884234
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.9411161223
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.5519428831
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 5.8419196723 15591091 19196722
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 5.8411731420 19196723 19196722 14580682 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 4.3419453300
MESH:D008545 Melanoma Tamoxifen 1.8519393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.9715990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.3619513568
MESH:D008569 Memory Disorders Ethanol 3.9915451040 18411066
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5816801185
MESH:D008679 Metaplasia Ozone 4.8910496685
MESH:D009101 Multiple Myeloma Capsaicin 4.0117505005
MESH:D009135 Muscular Diseases pirinixic acid 3.3016239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.0619151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8512213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.7916411023
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 8.973581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.973581430 9029167
MESH:D009362 Neoplasm Metastasis Tamoxifen 8.9719393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4519410462
MESH:D009369 Neoplasms pirinixic acid 1.8517405874
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 10.2219196722
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 10.2219200415 19189210 19196722
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2317954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1119348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.0114600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 2.786679447
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.6218514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.6220387270
MESH:D020078 Neurogenic Inflammation Capsaicin 4.8917961222
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9020387270
MESH:D009765 Obesity Capsaicin 4.6619056576
MESH:D009765 Obesity pirinixic acid 4.6620558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.246482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.813988306
MESH:D010146 Pain Acetaminophen 6.4416870215
MESH:D010146 Pain Capsaicin 6.4418987195 17043245 17084039 16996476 17434803 19081190
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.1816540662
MESH:D010190 Pancreatic Neoplasms Ethanol 5.1812384795
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4911578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.287296757
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0412520081
MESH:D010538 Peritonitis Ozone 3.9216369182
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.266228378
MESH:D011014 Pneumonia Ozone 4.1818929643 18381685 18007984
MESH:D011115 Polyneuropathies marker/mechanism
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3618163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.3612371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.362563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.9811399792 11896295 11222880 11118676
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.2115067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.1016919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.1616882103
MESH:D015427 Reperfusion Injury Capsaicin 6.4919211983 18460982
MESH:D015427 Reperfusion Injury pirinixic acid 6.4919058328
MESH:D012120 Respiration Disorders Chlorine 5.0018579056
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6418990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.223692021
MESH:D012640 Seizures Ethanol 3.039754883
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 5.268532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.2616192470
MESH:D013088 Spermatocele Ethinyl Estradiol 10.8516709447
MESH:D013088 Spermatocele Tamoxifen 10.8516709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.8319457130
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.5518456281
MESH:D013274 Stomach Neoplasms Ethanol 2.5518456281
MESH:D013276 Stomach Ulcer Ethanol 3.359562338 17189318 16755016 17918041 11906479 9211565
MESH:D013375 Substance Withdrawal Syndrome Ethanol 4.079754883
MESH:D013705 Temporomandibular Joint Disorders Capsaicin 5.5117997062
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6912697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 6.596587162 7505956 6582329 3712494 1399818
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 6.597505956
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 4.768074119
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 4.7616712894 17572228 8653321
MESH:D014581 Urticaria Acetaminophen 2.7810982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1014692618
MESH:D014605 Uveitis Cyclosporine 3.771336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3812125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3514671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0415886252
MESH:D014985 Xerophthalmia Cyclosporine 4.2317120751
Pathway ID Pathway Name
KEGG:01100 Metabolic pathways
REACT:22258 Metabolism of lipids and lipoproteins
KEGG:04146 Peroxisome
KEGG:03320 PPAR signaling pathway
KEGG:00120 Primary bile acid biosynthesis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA35014
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA449789glycine
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved