AutismKB 2.0

Annotation Detail for CCL5


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Basic Information Top
Gene Symbol:CCL5 ( D17S136E,MGC17164,RANTES,SCYA5,SISd,TCP228 )
Gene Full Name: chemokine (C-C motif) ligand 5
Band: 17q12
Quick LinksEntrez ID:6352; OMIM: 187011; Uniprot ID:CCL5_HUMAN; ENSEMBL ID: ENSG00000161570; HGNC ID: 10632
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05142Chagas disease
hsa05120Epithelial cell signaling in Helicobacter pylori infection
hsa04620Toll-like receptor signaling pathway
hsa04621NOD-like receptor signaling pathway
hsa04623Cytosolic DNA-sensing pathway
hsa04062Chemokine signaling pathway
hsa04060Cytokine-cytokine receptor interaction
hsa05020Prion diseases
Pathway IDPathway Name
Signaling by GPCR
Pathway IDPathway Name
200171Validated targets of C-MYC transcriptional repression
200134Syndecan-1-mediated signaling events
200115Syndecan-4-mediated signaling events
Pathway IDPathway Name
P00031Inflammation mediated by chemokine and cytokine signaling pathway
Pathway IDPathway Name
500406Chemokine receptors bind chemokines
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1770Melanoma
1781Rheumatoid arthritis
1800Lupus vulgaris
1804Chronic obstructive airway disease
1831Prostate cancer
1844Alcoholic liver disease
1877Multiple sclerosis
1901Endometriosis
1902Kidney failure
1904Diabetes mellitus
1918Atherosclerosis
1930Graves' disease
1946Thyroid gland disease
1998Enteritis
1841Stomach cancer
2005Bronchial disease
2024Basal cell carcinoma
2030Bronchiolitis
2040Hyperglycemia
2051Leukemia
2052Infection
2066Lung cancer
2081Pulmonary fibrosis
2097Hyperlipidemia
2100Hepatitis C
2114Thrombocytopenia
2146Lupus erythematosus
2166Influenza
2174Chronic rejection of renal transplant
2175HTLV-I infection
2208Synovitis
2220Dermatitis
2240Anemia
2241Infertility
Desease Name
Asthma. atopy. atopic dermatitis
cardiovascular disease
CARDIOVASCULAR
Kidney Failure, Chronic
kidney transplant
Asthma
atherosclerosis, carotid myocardial infarct
nephropathy in other diseases
RENAL
sclerosis, systemic
allergic rhinitis
IMMUNE
atopy
METABOLIC
HIV
hepatitis B
diabetes, type 2
Hepatitis C, Chronic
Nasal Polyps
INFECTION
No data
Desease Name
HIV-1 disease, delayed progression of
HIV-1 disease, rapid progression of
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C097949 1,25-dihydroxyvitamin D 1,25-dihydroxyvitamin D inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL5 protein]decreases reaction|increases secretion 16367934
C038983 1,3-dimethylthiourea 1,3-dimethylthiourea inhibits the reaction [Reactive Oxygen Species results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
C038983 1,3-dimethylthiourea 1,3-dimethylthiourea inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
C038983 1,3-dimethylthiourea 1,3-dimethylthiourea results in decreased expression of CCL5 mRNAdecreases expression 11128050
C004482 1-aminopyrene 1-aminopyrene results in increased expression of CCL5 mRNAincreases expression 19879285
C032668 1-nitropyrene 1-nitropyrene results in increased expression of CCL5 mRNAincreases expression 19879285
C005975 3,4-dihydroxyphenylethanol [Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in decreased expression of CCL5 mRNAaffects cotreatment|decreases expression 16797527
C046693 3-aminofluoranthene 3-aminofluoranthene results in increased expression of CCL5 mRNAincreases expression 19879285
C486633 4'-hydroxy-3'-methoxyacetophenone 4'-hydroxy-3'-methoxyacetophenone inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
C501474 4-OH-2',3,3',4',5'-pentachlorobiphenyl 4-OH-2',3,3',4',5'-pentachlorobiphenyl inhibits the reaction [Triiodothyronine results in increased expression of CCL5 mRNA]decreases reaction|increases expression 14761676
D000082 Acetaminophen Acetaminophen affects the expression of CCL5 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in increased expression of CCL5 mRNAincreases expression 15578514
D000082 Acetaminophen Acetaminophen inhibits the reaction [Vitamin K 3 results in increased expression of CCL5 mRNA]decreases reaction|increases expression 19265712
D000082 Acetaminophen Acetaminophen inhibits the reaction [Vitamin K 3 results in increased secretion of CCL5 protein]decreases reaction|increases secretion 19265712
D000111 Acetylcysteine Acetylcysteine inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
D000171 Acrolein Acrolein results in increased expression of CCL5 mRNAincreases expression 17950725
D000171 Acrolein CD8A protein promotes the reaction [Acrolein results in increased expression of CCL5 mRNA]increases expression|increases reaction 17950725
D000420 Albuterol [Beclomethasone co-treated with Albuterol] results in decreased secretion of CCL5 proteinaffects cotreatment|decreases secretion 15679717
D006710 Homocysteine [Homocysteine co-treated with Lipopolysaccharides] results in increased secretion of CCL5 proteinaffects cotreatment|increases secretion 16225753
D006710 Homocysteine Homocysteine results in increased expression of CCL5 mRNAincreases expression 16225753
D015081 2-Naphthylamine 2-Naphthylamine results in increased expression of CCL5 mRNAincreases expression 18247414
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CCL5 mRNAaffects expression 16483693
C416282 BAY 11-7085 BAY 11-7085 inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL5 protein]decreases reaction|increases expression 17015710
D001507 Beclomethasone [Beclomethasone co-treated with Albuterol] results in decreased secretion of CCL5 proteinaffects cotreatment|decreases secretion 15679717
D001507 Beclomethasone [Beclomethasone co-treated with formoterol] results in decreased secretion of CCL5 proteinaffects cotreatment|decreases secretion 15679717
D001554 Benzene Benzene results in increased expression of CCL5 proteinincreases expression 11306435
D001564 Benzo(a)pyrene Benzo(a)pyrene promotes the reaction [AHR protein results in increased expression of CCL5 protein]increases expression|increases reaction 12200463
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of CCL5 mRNAincreases expression 18247414
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of CCL5 proteinincreases expression 11306435
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of CCL5 mRNAdecreases expression 20713471
C004532 benzoquinone benzoquinone results in increased expression of CCL5 proteinincreases expression 17572062
C020711 beryllium sulfate beryllium sulfate results in increased expression of CCL5 mRNAincreases expression 16314022
D015124 8-Bromo Cyclic Adenosine Monophosphate 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Reactive Oxygen Species results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
D015124 8-Bromo Cyclic Adenosine Monophosphate 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
D002084 Butylated Hydroxytoluene Butylated Hydroxytoluene results in decreased expression of CCL5 mRNAdecreases expression 19925653
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of CCL5 mRNAincreases expression 14729362
15003993
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CCL5 mRNAaffects cotreatment|decreases expression 20360939
D000001 Calcimycin CCL5 protein promotes the reaction [Calcimycin affects the abundance of and affects the chemical synthesis of Reactive Oxygen Species]affects abundance|affects chemical synthesis|increases reaction 12797483
D000001 Calcimycin IL5 protein promotes the reaction [CCL5 protein promotes the reaction [Calcimycin affects the abundance of and affects the chemical synthesis of Reactive Oxygen Species]]affects abundance|affects chemical synthesis|increases reaction 12797483
D000001 Calcimycin [Calcimycin co-treated with CCL5 protein] results in increased secretion of Leukotriene B4affects cotreatment|increases secretion 18083043
D000001 Calcimycin CCL5 protein promotes the reaction [Calcimycin results in increased expression of ALOX5 mRNA]increases expression|increases reaction 18083043
D000001 Calcimycin CCL5 protein promotes the reaction [Calcimycin results in increased expression of ALOX5 protein]increases expression|increases reaction 18083043
D000001 Calcimycin Dexamethasone inhibits the reaction [[Calcimycin co-treated with CCL5 protein] results in increased secretion of Leukotriene B4]affects cotreatment|decreases reaction|increases secretion 18083043
D000001 Calcimycin Dexamethasone inhibits the reaction [[CCL5 protein co-treated with Calcimycin] results in increased expression of ALOX5 protein]affects cotreatment|decreases reaction|increases expression 18083043
D000001 Calcimycin Nordihydroguaiaretic Acid inhibits the reaction [[Calcimycin co-treated with CCL5 protein] results in increased secretion of Leukotriene B4]affects cotreatment|decreases reaction|increases secretion 18083043
D000001 Calcimycin Nordihydroguaiaretic Acid inhibits the reaction [[CCL5 protein co-treated with Calcimycin] results in increased expression of ALOX5 mRNA]affects cotreatment|decreases reaction|increases expression 18083043
D000001 Calcimycin Nordihydroguaiaretic Acid inhibits the reaction [[CCL5 protein co-treated with Calcimycin] results in increased expression of ALOX5 protein]affects cotreatment|decreases reaction|increases expression 18083043
D002118 Calcium CCL5 protein results in increased uptake of Calciumincreases uptake 10984371
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of CCL5 proteinincreases expression 17412915
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of CCL5 mRNAaffects expression 15963342
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of CCL5 mRNAdecreases expression 16239168
D002351 Carrageenan Carrageenan results in increased expression of CCL5 proteinincreases expression 12444156
D002351 Carrageenan isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CCL5 protein]decreases reaction|increases expression 14654164
D002351 Carrageenan Quercetin inhibits the reaction [Carrageenan results in increased expression of CCL5 protein]decreases reaction|increases expression 14654164
C034221 catechol catechol results in increased expression of CCL5 proteinincreases expression 17572062
C099555 CD 437 CD 437 results in decreased expression of CCL5 mRNAdecreases expression 12958071
C105934 celecoxib celecoxib results in decreased expression of CCL5 mRNAdecreases expression 12902868
C039671 ciglitazone ciglitazone inhibits the reaction [Thioglycolates results in increased secretion of CCL5 protein]decreases reaction|increases secretion 12624547
C433247 Cilomilast Cilomilast inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL5 protein]decreases reaction|increases expression 15491423
C055162 clopidogrel clopidogrel results in increased expression of CCL5 mRNAincreases expression 16856976
D003907 Dexamethasone Dexamethasone inhibits the reaction [[Toluene 2,4-Diisocyanate binds to ALB protein] which results in increased expression of CCL5 protein]affects binding|decreases reaction|increases expression 16908450
D003907 Dexamethasone Dexamethasone inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
D003907 Dexamethasone Dexamethasone inhibits the reaction [TNF protein results in increased expression of CCL5 protein]decreases reaction|increases expression 10495789
D003907 Dexamethasone Dexamethasone inhibits the reaction [[Calcimycin co-treated with CCL5 protein] results in increased secretion of Leukotriene B4]affects cotreatment|decreases reaction|increases secretion 18083043
D003907 Dexamethasone Dexamethasone inhibits the reaction [[CCL5 protein co-treated with Calcimycin] results in increased expression of ALOX5 protein]affects cotreatment|decreases reaction|increases expression 18083043
D002945 Cisplatin Cisplatin results in increased expression of CCL5 mRNAincreases expression 15814532
D002945 Cisplatin Cisplatin results in increased expression of CCL5 proteinincreases expression 15814532
D002945 Cisplatin pirinixic acid inhibits the reaction [Cisplatin results in increased expression of CCL5 mRNA]decreases reaction|increases expression 15814532
D002945 Cisplatin pirinixic acid inhibits the reaction [Cisplatin results in increased expression of CCL5 protein]decreases reaction|increases expression 15814532
D004041 Dietary Fats Dietary Fats results in increased expression of CCL5 mRNAincreases expression 18457598
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CCL5 mRNAaffects cotreatment|decreases expression 20360939
C014477 diflorasone diacetate diflorasone diacetate inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL5 protein]decreases reaction|increases expression 15491423
C014477 diflorasone diacetate diflorasone diacetate inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL5 protein]decreases reaction|increases expression 15491423
D015127 9,10-Dimethyl-1,2-benzanthracene 9,10-Dimethyl-1,2-benzanthracene promotes the reaction [AHR protein results in increased expression of CCL5 mRNA]increases expression|increases reaction 12200463
D004137 Dinitrochlorobenzene diflorasone diacetate inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL5 protein]decreases reaction|increases expression 15491423
D004137 Dinitrochlorobenzene Dinitrochlorobenzene results in increased expression of CCL5 proteinincreases expression 15491423
D004139 Dinitrofluorobenzene Dinitrofluorobenzene results in increased expression of CCL5 mRNAincreases expression 15719370
D004139 Dinitrofluorobenzene Dinitrofluorobenzene results in increased expression of CCL5 proteinincreases expression 15719370
D004391 Dust Dust results in decreased expression of CCL5 proteindecreases expression 17805423
D004391 Dust Dust results in increased expression of CCL5 mRNAincreases expression 17805423
D004958 Estradiol [Estradiol co-treated with norethindrone acetate] results in decreased expression of CCL5 proteinaffects cotreatment|decreases expression 16842799
D004958 Estradiol [Progesterone co-treated with Estradiol] results in decreased expression of CCL5 mRNAaffects cotreatment|decreases expression 17404688
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of CCL5 mRNAdecreases expression 12538720
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of CCL5 mRNAincreases expression 15885639
C007650 ethyl acetate ethyl acetate results in increased expression of CCL5 proteinincreases expression 11306435
C093230 fexofenadine fexofenadine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL5 mRNA]decreases reaction|increases expression 15460210
C093230 fexofenadine fexofenadine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL5 protein]decreases reaction|increases expression 15460210
C093230 fexofenadine fexofenadine inhibits the reaction [TNF protein results in increased expression of CCL5 protein]decreases reaction|increases expression 15460210
D005419 Flavonoids Flavonoids results in decreased expression of CCL5 mRNAdecreases expression 18035473
C012629 formoterol [Beclomethasone co-treated with formoterol] results in decreased secretion of CCL5 proteinaffects cotreatment|decreases secretion 15679717
D005576 Forskolin Forskolin inhibits the reaction [Reactive Oxygen Species results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
D005576 Forskolin Forskolin inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
D005620 Freund's Adjuvant [Urethane co-treated with Freund's Adjuvant] results in increased expression of CCL5 mRNAaffects cotreatment|increases expression 12400877
C007789 fucoidan fucoidan results in decreased expression of CCL5 proteindecreases expression 16201850
C043055 gallium arsenide gallium arsenide results in increased expression of CCL5 mRNAincreases expression 14560044
D007975 Leukotriene B4 [Calcimycin co-treated with CCL5 protein] results in increased secretion of Leukotriene B4affects cotreatment|increases secretion 18083043
D007975 Leukotriene B4 Dexamethasone inhibits the reaction [[Calcimycin co-treated with CCL5 protein] results in increased secretion of Leukotriene B4]affects cotreatment|decreases reaction|increases secretion 18083043
D007975 Leukotriene B4 Nordihydroguaiaretic Acid inhibits the reaction [[Calcimycin co-treated with CCL5 protein] results in increased secretion of Leukotriene B4]affects cotreatment|decreases reaction|increases secretion 18083043
D006586 Hexanes Hexanes results in increased expression of CCL5 proteinincreases expression 11306435
D006820 Hyaluronic Acid Hyaluronic Acid analog results in increased secretion of CCL5 proteinincreases secretion 9278343
C031927 hydroquinone hydroquinone results in increased expression of CCL5 proteinincreases expression 17572062
C013038 hydroxyhydroquinone hydroxyhydroquinone affects the expression of CCL5 proteinaffects expression 17572062
D015759 Ionomycin [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL5 proteinaffects cotreatment|increases expression 17572062
D007501 Iron Iron deficiency results in increased expression of CCL5 mRNAincreases expression 20368581
C016527 isoquercitrin isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CCL5 protein]decreases reaction|increases expression 14654164
C006552 kaempferol [Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in decreased expression of CCL5 mRNAaffects cotreatment|decreases expression 16797527
D008070 Lipopolysaccharides 1,25-dihydroxyvitamin D inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL5 protein]decreases reaction|increases secretion 16367934
D008070 Lipopolysaccharides fexofenadine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL5 mRNA]decreases reaction|increases expression 15460210
D008070 Lipopolysaccharides fexofenadine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL5 protein]decreases reaction|increases expression 15460210
D008070 Lipopolysaccharides [Homocysteine co-treated with Lipopolysaccharides] results in increased secretion of CCL5 proteinaffects cotreatment|increases secretion 16225753
D008070 Lipopolysaccharides Lipopolysaccharides promotes the reaction [Shiga Toxin 2 results in increased secretion of CCL5 protein]increases reaction|increases secretion 16366002
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of CCL5 mRNAincreases expression 15460210
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of CCL5 proteinincreases expression 18684396
15460210
D008070 Lipopolysaccharides Lipopolysaccharides results in increased secretion of CCL5 proteinincreases secretion 16367934
D008070 Lipopolysaccharides IL6 protein affects the reaction [Lipopolysaccharides results in increased secretion of CCL5 protein]affects reaction|increases secretion 15804595
D008070 Lipopolysaccharides [Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CCL5 proteinaffects cotreatment|increases expression 15135318
D008070 Lipopolysaccharides mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CCL5 protein]affects cotreatment|decreases reaction|increases expression 15135318
C013592 mangiferin mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CCL5 protein]affects cotreatment|decreases reaction|increases expression 15135318
D008748 Methylcholanthrene Methylcholanthrene results in decreased expression of CCL5 mRNAdecreases expression 20713471
D008770 Methylnitrosourea Methylnitrosourea results in increased expression of CCL5 mRNAincreases expression 15240709
D009151 Mustard Gas Mustard Gas results in increased expression of CCL5 proteinincreases expression 17620002
D009151 Mustard Gas Mustard Gas results in increased expression of CCL5 mRNAincreases expression 18988085
D009173 Mycophenolic Acid Mycophenolic Acid results in decreased expression of CCL5 mRNAdecreases expression 10688038
D009173 Mycophenolic Acid [Quercetin co-treated with Mycophenolic Acid] results in decreased expression of CCL5 mRNAaffects cotreatment|decreases expression 10688038
D009538 Nicotine Nicotine results in increased expression of CCL5 mRNAincreases expression 18247414
D009569 Nitric Oxide Nitric Oxide results in decreased secretion of CCL5 proteindecreases secretion 13678430
D020030 Nitric Oxide Donors Nitric Oxide Donors results in decreased secretion of CCL5 proteindecreases secretion 13678430
D026422 S-Nitrosoglutathione S-Nitrosoglutathione results in decreased secretion of CCL5 proteindecreases secretion 13678430
D009637 Nordihydroguaiaretic Acid Nordihydroguaiaretic Acid inhibits the reaction [[Calcimycin co-treated with CCL5 protein] results in increased secretion of Leukotriene B4]affects cotreatment|decreases reaction|increases secretion 18083043
D009637 Nordihydroguaiaretic Acid Nordihydroguaiaretic Acid inhibits the reaction [[CCL5 protein co-treated with Calcimycin] results in increased expression of ALOX5 mRNA]affects cotreatment|decreases reaction|increases expression 18083043
D009637 Nordihydroguaiaretic Acid Nordihydroguaiaretic Acid inhibits the reaction [[CCL5 protein co-treated with Calcimycin] results in increased expression of ALOX5 protein]affects cotreatment|decreases reaction|increases expression 18083043
C024262 norethindrone acetate [Estradiol co-treated with norethindrone acetate] results in decreased expression of CCL5 proteinaffects cotreatment|decreases expression 16842799
D010126 Ozone Ozone results in decreased expression of CCL5 mRNAdecreases expression 12763052
D010743 Phospholipids CCL2 protein promotes the reaction [Phospholipids results in increased expression of CCL5 mRNA]increases expression|increases reaction 11937571
D010743 Phospholipids Phospholipids results in increased expression of CCL5 mRNAincreases expression 11937571
C060836 pioglitazone pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL5 protein]decreases reaction|increases expression 17015710
C006253 pirinixic acid pirinixic acid inhibits the reaction [Cisplatin results in increased expression of CCL5 mRNA]decreases reaction|increases expression 15814532
C006253 pirinixic acid pirinixic acid inhibits the reaction [Cisplatin results in increased expression of CCL5 protein]decreases reaction|increases expression 15814532
C006253 pirinixic acid pirinixic acid results in decreased expression of CCL5 mRNAdecreases expression 17426115
C006253 pirinixic acid pirinixic acid results in decreased expression of CCL5 mRNAdecreases expression 12832660
D011078 Polychlorinated Biphenyls Polychlorinated Biphenyls inhibits the reaction [Triiodothyronine results in increased expression of CCL5 mRNA]decreases reaction|increases expression 14761676
D011374 Progesterone [Progesterone co-treated with Estradiol] results in decreased expression of CCL5 mRNAaffects cotreatment|decreases expression 17404688
D015232 Dinoprostone Dinoprostone results in decreased expression of CCL5 mRNAdecreases expression 16303787
D015232 Dinoprostone Dinoprostone inhibits the reaction [Reactive Oxygen Species results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
D015232 Dinoprostone Dinoprostone inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
C020972 pyrrolidine dithiocarbamic acid pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
D011794 Quercetin [Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in decreased expression of CCL5 mRNAaffects cotreatment|decreases expression 16797527
D011794 Quercetin Quercetin results in increased expression of CCL5 mRNAincreases expression 16455785
D011794 Quercetin [Quercetin co-treated with Mycophenolic Acid] results in decreased expression of CCL5 mRNAaffects cotreatment|decreases expression 10688038
D011794 Quercetin Quercetin inhibits the reaction [Carrageenan results in increased expression of CCL5 protein]decreases reaction|increases expression 14654164
D011794 Quercetin Quercetin results in decreased expression of CCL5 mRNAdecreases expression 10688038
D020849 Raloxifene Raloxifene results in decreased expression of CCL5 proteindecreases expression 16842799
D017382 Reactive Oxygen Species CCL5 protein promotes the reaction [Calcimycin affects the abundance of and affects the chemical synthesis of Reactive Oxygen Species]affects abundance|affects chemical synthesis|increases reaction 12797483
D017382 Reactive Oxygen Species IL5 protein promotes the reaction [CCL5 protein promotes the reaction [Calcimycin affects the abundance of and affects the chemical synthesis of Reactive Oxygen Species]]affects abundance|affects chemical synthesis|increases reaction 12797483
D017382 Reactive Oxygen Species 1,3-dimethylthiourea inhibits the reaction [Reactive Oxygen Species results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
D017382 Reactive Oxygen Species 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Reactive Oxygen Species results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
D017382 Reactive Oxygen Species Dinoprostone inhibits the reaction [Reactive Oxygen Species results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
D017382 Reactive Oxygen Species Forskolin inhibits the reaction [Reactive Oxygen Species results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
D017382 Reactive Oxygen Species Reactive Oxygen Species results in increased expression of CCL5 mRNAincreases expression 10495789
D017382 Reactive Oxygen Species tetramethylthiourea inhibits the reaction [Reactive Oxygen Species results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
C059514 resveratrol resveratrol analog results in decreased expression of CCL5 mRNAdecreases expression 15652768
C059514 resveratrol resveratrol results in decreased expression of CCL5 proteindecreases expression 17872969
D015474 Isotretinoin Isotretinoin inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]decreases reaction|increases expression 15972972
D015474 Isotretinoin Isotretinoin inhibits the reaction [TNF protein results in increased secretion of CCL5 protein]decreases reaction|increases secretion 15972972
D015474 Isotretinoin Isotretinoin results in decreased expression of CCL5 mRNAdecreases expression 15972972
D015474 Isotretinoin Isotretinoin results in decreased expression of CCL5 mRNAdecreases expression 15972972
C089730 rosiglitazone rosiglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL5 protein]decreases reaction|increases expression 17015710
C093642 SB 203580 SB 203580 inhibits the reaction [[Toluene 2,4-Diisocyanate binds to ALB protein] which results in increased expression of CCL5 protein]affects binding|decreases reaction|increases expression 16908450
D017632 Asbestos, Serpentine Asbestos, Serpentine results in increased expression of CCL5 proteinincreases expression 17200189
D017632 Asbestos, Serpentine PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of CCL5 protein]affects reaction|increases expression 17200189
D022641 Shiga Toxin 2 Lipopolysaccharides promotes the reaction [Shiga Toxin 2 results in increased secretion of CCL5 protein]increases reaction|increases secretion 16366002
D022641 Shiga Toxin 2 Shiga Toxin 2 results in increased secretion of CCL5 proteinincreases secretion 16366002
D013467 Sulindac Sulindac inhibits the reaction [IL1B protein results in increased expression of CCL5 mRNA]decreases reaction|increases expression 16159934
D013467 Sulindac Sulindac inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]decreases reaction|increases expression 16159934
D014284 Triiodothyronine 4-OH-2',3,3',4',5'-pentachlorobiphenyl inhibits the reaction [Triiodothyronine results in increased expression of CCL5 mRNA]decreases reaction|increases expression 14761676
D014284 Triiodothyronine Polychlorinated Biphenyls inhibits the reaction [Triiodothyronine results in increased expression of CCL5 mRNA]decreases reaction|increases expression 14761676
D014284 Triiodothyronine Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine results in increased expression of CCL5 mRNA]increases expression|increases reaction 14761676
D014284 Triiodothyronine Triiodothyronine results in increased expression of CCL5 mRNAincreases expression 14761676
D013619 Tacrine Tacrine results in decreased expression of CCL5 mRNAdecreases expression 12832660
D016559 Tacrolimus Tacrolimus results in decreased expression of CCL5 mRNAdecreases expression 15948978
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin promotes the reaction [[AHR protein binds to CCL5 enhancer] which results in increased expression of CCL5 mRNA]affects binding|increases expression|increases reaction 12200463
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin promotes the reaction [AHR protein results in increased expression of CCL5 mRNA]increases expression|increases reaction 12200463
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin promotes the reaction [AHR protein results in increased expression of CCL5 protein]increases expression|increases reaction 12200463
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine results in increased expression of CCL5 mRNA]increases expression|increases reaction 14761676
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CCL5 mRNAincreases expression 12200463
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of CCL5 mRNAdecreases expression 18684927
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of CCL5 mRNAdecreases expression 20059583
D013755 Tetradecanoylphorbol Acetate [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL5 proteinaffects cotreatment|increases expression 17572062
C019107 tetramethylthiourea tetramethylthiourea inhibits the reaction [Reactive Oxygen Species results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
C019107 tetramethylthiourea tetramethylthiourea inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]decreases reaction|increases expression 10495789
C019107 tetramethylthiourea tetramethylthiourea results in decreased expression of CCL5 mRNAdecreases expression 11128050
D013864 Thioglycolates ciglitazone inhibits the reaction [Thioglycolates results in increased secretion of CCL5 protein]decreases reaction|increases secretion 12624547
D013864 Thioglycolates Thioglycolates results in increased secretion of CCL5 proteinincreases secretion 12624547
D014051 Toluene 2,4-Diisocyanate CCL5 gene polymorphism affects the susceptibility to Toluene 2,4-Diisocyanateaffects response to substance 18447907
D014051 Toluene 2,4-Diisocyanate Dexamethasone inhibits the reaction [[Toluene 2,4-Diisocyanate binds to ALB protein] which results in increased expression of CCL5 protein]affects binding|decreases reaction|increases expression 16908450
D014051 Toluene 2,4-Diisocyanate EGFR protein affects the reaction [[Toluene 2,4-Diisocyanate binds to ALB protein] which results in increased expression of CCL5 protein]affects binding|affects reaction|increases expression 16908450
D014051 Toluene 2,4-Diisocyanate SB 203580 inhibits the reaction [[Toluene 2,4-Diisocyanate binds to ALB protein] which results in increased expression of CCL5 protein]affects binding|decreases reaction|increases expression 16908450
D014051 Toluene 2,4-Diisocyanate [Toluene 2,4-Diisocyanate binds to ALB protein] which results in increased expression of CCL5 proteinaffects binding|increases expression 16908450
D014051 Toluene 2,4-Diisocyanate BAY 11-7085 inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL5 protein]decreases reaction|increases expression 17015710
D014051 Toluene 2,4-Diisocyanate Cilomilast inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL5 protein]decreases reaction|increases expression 15491423
D014051 Toluene 2,4-Diisocyanate diflorasone diacetate inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL5 protein]decreases reaction|increases expression 15491423
D014051 Toluene 2,4-Diisocyanate pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL5 protein]decreases reaction|increases expression 17015710
D014051 Toluene 2,4-Diisocyanate PPARG protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL5 protein]affects reaction|increases expression 17015710
D014051 Toluene 2,4-Diisocyanate rosiglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL5 protein]decreases reaction|increases expression 17015710
D014051 Toluene 2,4-Diisocyanate TNF protein affects the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL5 mRNA]affects reaction|increases expression 12356572
D014051 Toluene 2,4-Diisocyanate Toluene 2,4-Diisocyanate results in increased expression of CCL5 mRNAincreases expression 11467998
12356572
D014051 Toluene 2,4-Diisocyanate Toluene 2,4-Diisocyanate results in increased expression of CCL5 proteinincreases expression 15491423
17015710
D014051 Toluene 2,4-Diisocyanate Toluene 2,4-Diisocyanate results in increased expression of CCL5 mRNAincreases expression 15823807
D014212 Tretinoin Tretinoin results in decreased expression of CCL5 proteindecreases expression 17118196
D014520 Urethane [Urethane co-treated with Freund's Adjuvant] results in increased expression of CCL5 mRNAaffects cotreatment|increases expression 12400877
C034028 vanadyl sulfate vanadyl sulfate results in increased expression of CCL5 proteinincreases expression 18684396
D001335 Vehicle Emissions Vehicle Emissions results in increased expression of CCL5 proteinincreases expression 11306435
C025643 vinclozolin vinclozolin affects the expression of CCL5 mRNAaffects expression 19015723
D014810 Vitamin E [Vitamin E co-treated with Quercetin co-treated with kaempferol co-treated with 3,4-dihydroxyphenylethanol] results in decreased expression of CCL5 mRNAaffects cotreatment|decreases expression 16797527
D024483 Vitamin K 3 Acetaminophen inhibits the reaction [Vitamin K 3 results in increased expression of CCL5 mRNA]decreases reaction|increases expression 19265712
D024483 Vitamin K 3 Acetaminophen inhibits the reaction [Vitamin K 3 results in increased secretion of CCL5 protein]decreases reaction|increases secretion 19265712
D024483 Vitamin K 3 Vitamin K 3 results in increased expression of CCL5 mRNAincreases expression 19265712
D024483 Vitamin K 3 Vitamin K 3 results in increased secretion of CCL5 proteinincreases secretion 19265712
C020174 WR 1065 WR 1065 results in increased expression of CCL5 mRNAincreases expression 12007958
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Sulindac 4.5714745880
MESH:D000014 Abnormalities, Drug-Induced Isotretinoin 5.7318769834
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 5.7314514962 15322242 11752688
MESH:D000015 Abnormalities, Multiple Isotretinoin 4.1518769834
MESH:D000138 Acidosis Ammonium Chloride 2.6618287403
MESH:D017486 Acneiform Eruptions Isotretinoin 5.3616232082
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 8.9317505938
MESH:D000152 Acne Vulgaris Isotretinoin 8.9318769834 16185265
MESH:D054058 Acute Coronary Syndrome clopidogrel 5.0919106084
MESH:D058186 Acute Kidney Injury Cisplatin 9.8212690470 15814532 17670903
MESH:D058186 Acute Kidney Injury resveratrol 9.8216538975
MESH:D058186 Acute Kidney Injury Sulindac 9.827897758
MESH:D055371 Acute Lung Injury Acrolein 10.5020525806 21297076
MESH:D055371 Acute Lung Injury Lipopolysaccharides 10.5011850527 18653653
MESH:D055371 Acute Lung Injury pirinixic acid 10.5018653653
MESH:D000210 Acute-Phase Reaction Thioglycolates 5.449464241
MESH:D000230 Adenocarcinoma 9,10-Dimethyl-1,2-benzanthracene 18.4612844480 10697514
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 18.4620464547 20127859
MESH:D000230 Adenocarcinoma Cisplatin 18.4611798837 17638652
MESH:D000230 Adenocarcinoma Estradiol 18.4611473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 18.4614692618
MESH:D000230 Adenocarcinoma Methylnitrosourea 18.4615113128 15688392
MESH:D000230 Adenocarcinoma Sulindac 18.4611910360
MESH:D000230 Adenocarcinoma Urethane 18.4618316556
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Urethane 4.7815814487
MESH:D000236 Adenoma 9,10-Dimethyl-1,2-benzanthracene 22.3011376689
MESH:D000236 Adenoma Benzo(a)pyrene 22.306695378
MESH:D000236 Adenoma Diethylnitrosamine 22.3010737359 6695378
MESH:D000236 Adenoma Methylcholanthrene 22.3010545420 6695378
MESH:D000236 Adenoma resveratrol 22.3015688382
MESH:D000236 Adenoma Sulindac 22.3010223192
MESH:D000236 Adenoma Urethane 22.3016926031 6695378 17195641 10822126 10530776 11497255 17093202
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 12.0618056438 16434500 17162532 19061943 17620307 19052882
MESH:D018248 Adenoma, Liver Cell pirinixic acid 12.0616434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 12.0616835633
MESH:D011125 Adenomatous Polyposis Coli celecoxib 16.5519003578 16215675
MESH:D011125 Adenomatous Polyposis Coli Dinoprostone 16.5517942926
MESH:D011125 Adenomatous Polyposis Coli Leukotriene B4 16.5517942926
MESH:D011125 Adenomatous Polyposis Coli Sulindac 16.5511874996 19003578 11535846 12394442 17611924 16460482 15623613
MESH:D000419 Albuminuria Raloxifene 3.7217308373 17451421
OMIM:607154 ALLERGIC RHINITIS fexofenadine 4.9116037679
MESH:D000505 Alopecia Tretinoin 2.8615955085
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 4.7416640825
MESH:D000544 Alzheimer Disease Acrolein 20.1717570602 15207723 14715435
MESH:D000544 Alzheimer Disease Iron 20.1716563566 16640825
MESH:D000544 Alzheimer Disease Nicotine 20.1716627626
MESH:D000544 Alzheimer Disease Nitric Oxide 20.1717556102
MESH:D000544 Alzheimer Disease Ozone 20.1715513908
MESH:D000544 Alzheimer Disease Raloxifene 20.1715800139
MESH:D000544 Alzheimer Disease resveratrol 20.1716183991 16162502
MESH:D000544 Alzheimer Disease rosiglitazone 20.1719621015
MESH:D000544 Alzheimer Disease Tacrine 20.1712725862
MESH:D000707 Anaphylaxis mangiferin 4.5816536907 14669257
MESH:D000740 Anemia Iron 6.2416566752 16434484
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.2411748828
MESH:D000741 Anemia, Aplastic Benzene 3.6217661222 14761424 11369114
MESH:D000743 Anemia, Hemolytic Quercetin 3.4117084956
MESH:D018798 Anemia, Iron-Deficiency Iron 3.8417147795 16569441 17375513 17162259 17163184
MESH:D000756 Anemia, Sideroblastic Iron 3.9816910769
MESH:D000799 Angioedema Acetaminophen 2.9210982225
MESH:D001008 Anxiety Disorders vinclozolin 2.8919015723
MESH:D001014 Aortic Aneurysm Dinoprostone 4.7310231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 9.0319183758
MESH:D017544 Aortic Aneurysm, Abdominal Dinoprostone 9.0310388637
MESH:D001145 Arrhythmias, Cardiac Iron 3.5716604332
MESH:D001161 Arteriosclerosis Acrolein 12.0115014928
MESH:D001161 Arteriosclerosis Dietary Fats 12.0115238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 12.0111256880
MESH:D001168 Arthritis Leukotriene B4 5.2611006272
MESH:D001169 Arthritis, Experimental Carrageenan 16.2717392412
MESH:D001169 Arthritis, Experimental Dexamethasone 16.2717659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 16.2715885639
MESH:D001169 Arthritis, Experimental resveratrol 16.2717115116
MESH:D001169 Arthritis, Experimental Tretinoin 16.2716412693
MESH:D001172 Arthritis, Rheumatoid Ozone 3.5715570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 3.5716292516
MESH:D001195 Asbestosis Asbestos, Serpentine 4.8010751356
MESH:D001249 Asthma Albuterol 23.329949315 11991558
MESH:D001249 Asthma Beclomethasone 23.3212114351 8762487
MESH:D001249 Asthma Cilomilast 23.3216956605
MESH:D001249 Asthma formoterol 23.3210967152 12113382
MESH:D001249 Asthma Leukotriene B4 23.3219667530 11006272
MESH:D001249 Asthma Mustard Gas 23.3210378619
MESH:D001249 Asthma Ozone 23.3217854713 16373670
MESH:D001249 Asthma Toluene 2,4-Diisocyanate 23.32170078 15590891 17015710 11077013 10934080 12762349 18394133 20032816 7684630 12585506 3040596 15855793 19187332 6091946 16210060 11742282 8156442 16792590 12684321 11467998 6091945 15590890 10797510
MESH:D001249 Asthma Tretinoin 23.3216456186
MESH:D001250 Asthma, Exercise-Induced Leukotriene B4 4.9919667531
MESH:D001260 Ataxia Telangiectasia Iron 10.0915336622
MESH:D001260 Ataxia Telangiectasia Quercetin 10.0915336622
MESH:D050197 Atherosclerosis Acrolein 14.0117363696 16126721 16037261
MESH:D050197 Atherosclerosis Iron 14.0116632123 16640825
MESH:D050197 Atherosclerosis mangiferin 14.0118450471
MESH:D050197 Atherosclerosis Methylcholanthrene 14.0111922910
MESH:D050197 Atherosclerosis resveratrol 14.0116873680 17967414
MESH:D001321 Autistic Disorder Acetaminophen 2.2818445737
MESH:D001321 Autistic Disorder Homocysteine 2.2816297937 20468076
MESH:D001321 Autistic Disorder Iron 2.2817352947
MESH:D001321 Autistic Disorder pioglitazone 2.2817207275
MESH:D001327 Autoimmune Diseases Quercetin 3.5219761891
MESH:D001424 Bacterial Infections Iron 4.2916640825
MESH:D001471 Barrett Esophagus Tretinoin 3.5316935849
MESH:D001477 Bartter Syndrome Dinoprostone 4.8515976003
MESH:D001768 Blister Mustard Gas 4.2519167455
MESH:D001778 Blood Coagulation Disorders pirinixic acid 10.4919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 10.4912125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 10.4916206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 2.8715340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.1115746008
MESH:D001855 Bone Marrow Diseases Benzene 4.3016183116
MESH:D019046 Bone Marrow Neoplasms Cisplatin 3.9614601052
MESH:D001862 Bone Resorption Freund's Adjuvant 7.5916769263
MESH:D001862 Bone Resorption mangiferin 7.599881647
MESH:D001913 Bowen's Disease Sulindac 4.4311207687
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.4117868700
MESH:D001930 Brain Injuries Progesterone 8.0215665606 15845082 15380490
MESH:D001930 Brain Injuries Raloxifene 8.0216580743
MESH:D002545 Brain Ischemia resveratrol 3.3817600658
MESH:D001943 Breast Neoplasms 9,10-Dimethyl-1,2-benzanthracene 18.6617127718 20435547 18840765 15565634 16153821
MESH:D001943 Breast Neoplasms Benzene 18.6617162533 11921183
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 18.6620146248 17474063
MESH:D001943 Breast Neoplasms Cisplatin 18.6619526202 18382427
MESH:D001943 Breast Neoplasms Dietary Fats 18.6620435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 18.6617474063
MESH:D001943 Breast Neoplasms Estradiol 18.6619861407 17261762 18497071 16675129 14630087 12948864 17018787 17289903
MESH:D001943 Breast Neoplasms kaempferol 18.6616756079
MESH:D001943 Breast Neoplasms Methylcholanthrene 18.6617474063
MESH:D001943 Breast Neoplasms Methylnitrosourea 18.6611306469 16253758 14633655
MESH:D001943 Breast Neoplasms Nitric Oxide 18.6615631943
MESH:D001943 Breast Neoplasms Nordihydroguaiaretic Acid 18.6618418215
MESH:D001943 Breast Neoplasms Progesterone 18.6616175315 17614352 15562024
MESH:D001943 Breast Neoplasms Quercetin 18.6618628248
MESH:D001943 Breast Neoplasms Raloxifene 18.6617049068 15758505 17595753 17261762 17440819 17952589 16837676 15775269 17242785 17893378 15572757 16912660
MESH:D001943 Breast Neoplasms resveratrol 18.6617534123 17651959 16393696
MESH:D001943 Breast Neoplasms Sulindac 18.6616642371
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 18.6620435547
MESH:D001943 Breast Neoplasms Toluene 2,4-Diisocyanate 18.6611921183
MESH:D001943 Breast Neoplasms Tretinoin 18.6616443354 16166294 16873071
MESH:D016535 Bronchial Hyperreactivity Leukotriene B4 10.1312654629 12794006
MESH:D016535 Bronchial Hyperreactivity Ozone 10.1317626835 16777450 19059883 18417511 14754758 15516495 18315731
MESH:D016535 Bronchial Hyperreactivity Toluene 2,4-Diisocyanate 10.138156442 15590891 12507178
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.2515286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.0517687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.6816813970
MESH:D002100 Cachexia Ozone 3.8316183385
MESH:D002105 Cadmium Poisoning Quercetin 4.6216962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.5516111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 6.9916050911 16011737 15673190 16097048 3786805 16124888 15700767 10355542 16192424 18705752 15721981 16227642
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 6.9916050911
MESH:D002277 Carcinoma Methylcholanthrene 5.8310545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 5.8316835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.2316168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 12.433084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 12.4318788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 12.4317982673
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 12.4319822196 16569478 18665156 19107877 3084413 20101231 18494052 16540662 19519916 19383236 10737359 19208518 18691550 16698587 20512989 17055752 18971187 19919837 16681979 18978308 20524982 20214788 18210153 16830150 19052882 16935385 19418558 19171122 18785209 17138121 19394651 19539802 18056438 16502159 17761372 17978847 21159647 20727157 3581430 10672840 16779866 16288022 18393292 17173139 17162532 18788625 11831363 16878318 20007298 20514400 16807293 19701751 20432363 16328049 17428255 18506893 20935162 20084675 19335982
MESH:D006528 Carcinoma, Hepatocellular Estradiol 12.4316924424
MESH:D006528 Carcinoma, Hepatocellular Quercetin 12.4312508355 19519916
MESH:D006528 Carcinoma, Hepatocellular resveratrol 12.4319321006 16227395
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 12.431917145
MESH:D018827 Carcinoma, Lewis Lung resveratrol 3.6816675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.6316685392 12023789
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.0617234771
MESH:D002292 Carcinoma, Renal Cell celecoxib 3.6716369983
MESH:D002294 Carcinoma, Squamous Cell 9,10-Dimethyl-1,2-benzanthracene 19.1411376689
MESH:D002294 Carcinoma, Squamous Cell Acetylcysteine 19.1417015178
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 19.1420419170
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 19.1418337622 17066447 6189445
MESH:D002294 Carcinoma, Squamous Cell Isotretinoin 19.1411237771
MESH:D002294 Carcinoma, Squamous Cell resveratrol 19.1416227395
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 19.1418922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 19.1416096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 3.2717572228
MESH:D006332 Cardiomegaly Quercetin 4.8219794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 4.8218670907 18850075 16120746
MESH:D009202 Cardiomyopathies Iron 3.3916640825
MESH:D002311 Cardiomyopathy, Dilated Iron 3.0516604332
MESH:D002318 Cardiovascular Diseases clopidogrel 15.5220180610
MESH:D002318 Cardiovascular Diseases kaempferol 15.5216756079
MESH:D002318 Cardiovascular Diseases Raloxifene 15.5215775269
MESH:D002318 Cardiovascular Diseases resveratrol 15.5215458977
MESH:D002318 Cardiovascular Diseases Tacrolimus 15.5217703430
MESH:D002386 Cataract Acetaminophen 8.8110977129
MESH:D002386 Cataract Methylnitrosourea 8.8112484553
MESH:D002386 Cataract Tretinoin 8.8117460283
MESH:D002471 Cell Transformation, Neoplastic Acetylcysteine 17.5418226522
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 17.5421159647 2727394 7505956 17174075
MESH:D002471 Cell Transformation, Neoplastic Dinoprostone 17.5416192471
MESH:D002471 Cell Transformation, Neoplastic Estradiol 17.5418566989
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 17.5416192471
MESH:D002471 Cell Transformation, Neoplastic Methylnitrosourea 17.547505956 2727394
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.6816129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 6.6919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 6.6916835633
MESH:D002779 Cholestasis Ethinyl Estradiol 9.3615861022 17681005 11677210 17333356 16919318 17110522 16105132
MESH:D002779 Cholestasis Nitric Oxide 9.3616919318
MESH:D002779 Cholestasis pirinixic acid 9.3619176532
MESH:D002822 Choriocarcinoma Tretinoin 4.2316461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 7.0312621046 8697196 15340226 16354765 15668235
MESH:D002972 Cleft Palate Tretinoin 7.039407595
MESH:D002972 Cleft Palate Urethane 7.0312810352
MESH:D003072 Cognition Disorders Raloxifene 3.7315800139
MESH:D003092 Colitis resveratrol 6.6916474422
MESH:D003092 Colitis Tretinoin 6.6917035595
MESH:D003093 Colitis, Ulcerative Dinitrochlorobenzene 3.4517373747 19159591
MESH:D003110 Colonic Neoplasms celecoxib 12.8216004971
MESH:D003110 Colonic Neoplasms Dexamethasone 12.8215824018
MESH:D003110 Colonic Neoplasms Iron 12.8216640825
MESH:D003110 Colonic Neoplasms Nordihydroguaiaretic Acid 12.8215936596
MESH:D003110 Colonic Neoplasms Quercetin 12.8215741050 17148506 11134977 19440933 16640504 17191121 19056647
MESH:D003110 Colonic Neoplasms resveratrol 12.8216338953
MESH:D003110 Colonic Neoplasms Sulindac 12.8212902858 12458338
MESH:D015179 Colorectal Neoplasms Acrolein 7.9217597105
MESH:D015179 Colorectal Neoplasms celecoxib 7.9211197048 18349538
MESH:D015179 Colorectal Neoplasms Cisplatin 7.9215273666
MESH:D015179 Colorectal Neoplasms Polychlorinated Biphenyls 7.9215531428
MESH:D015179 Colorectal Neoplasms Quercetin 7.9218852136 18095365
MESH:D015179 Colorectal Neoplasms resveratrol 7.9216550006
MESH:D015179 Colorectal Neoplasms Sulindac 7.9218059344 10666051 11197048 11076880
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.2714669216 17141729
MESH:D003324 Coronary Artery Disease Homocysteine 3.3316379339
MESH:D003327 Coronary Disease resveratrol 3.1016507316
MESH:D019465 Craniofacial Abnormalities Benzene 8.9015643154
MESH:D019465 Craniofacial Abnormalities Dexamethasone 8.9017728286
MESH:D019465 Craniofacial Abnormalities Isotretinoin 8.9018769834 9879862
MESH:D019465 Craniofacial Abnormalities Reactive Oxygen Species 8.9015736158
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 8.9020055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 8.909125849 16925845 9142499 17551590 9224671 8800419 9211117 10589399 9664655 14991402
MESH:D019465 Craniofacial Abnormalities Vitamin E 8.9019769572
MESH:D003456 Cryptorchidism vinclozolin 3.4714966744
MESH:D003457 Cryptosporidiosis mangiferin 4.9316547730
MESH:D003550 Cystic Fibrosis Acetylcysteine 6.7019747007
MESH:D003550 Cystic Fibrosis pioglitazone 6.7019747007
MESH:D003556 Cystitis Acrolein 4.4712161096
MESH:D003704 Dementia Polychlorinated Biphenyls 3.8716140633
MESH:D015140 Dementia, Vascular Nitric Oxide 5.0517556102
MESH:D003865 Depressive Disorder, Major Raloxifene 3.3717474826
MESH:D003872 Dermatitis Benzene 3.8815902427
MESH:D017449 Dermatitis, Allergic Contact Cilomilast 12.7012956900
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 12.7012438553
MESH:D017449 Dermatitis, Allergic Contact diflorasone diacetate 12.7012956900
MESH:D017449 Dermatitis, Allergic Contact Dinitrochlorobenzene 12.7015491423
MESH:D017449 Dermatitis, Allergic Contact Toluene 2,4-Diisocyanate 12.7018759878 15491423 12956900
MESH:D003876 Dermatitis, Atopic marker/mechanism 18249437
MESH:D003876 Dermatitis, Atopic fexofenadine 5.4717133778
MESH:D003876 Dermatitis, Atopic pirinixic acid 5.4718249437
MESH:D003877 Dermatitis, Contact Toluene 2,4-Diisocyanate 3.9517010967
MESH:D003920 Diabetes Mellitus Iron 7.0416604332 16640825
MESH:D003920 Diabetes Mellitus rosiglitazone 7.0417446233
MESH:D003921 Diabetes Mellitus, Experimental mangiferin 13.6112093613 19028559
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 13.6119496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 13.6116873680
MESH:D003921 Diabetes Mellitus, Experimental vanadyl sulfate 13.6116684804
MESH:D003922 Diabetes Mellitus, Type 1 Iron 2.9916506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 12.6820387270
MESH:D003924 Diabetes Mellitus, Type 2 Iron 12.6816506275
MESH:D003924 Diabetes Mellitus, Type 2 mangiferin 12.689881663 11315760
MESH:D003924 Diabetes Mellitus, Type 2 pioglitazone 12.6812642470 16023994
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 12.6812642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 12.6817107852
MESH:D003928 Diabetic Nephropathies Estradiol 15.0419279558
MESH:D003928 Diabetic Nephropathies mangiferin 15.0419960420 19706694
MESH:D003928 Diabetic Nephropathies Raloxifene 15.0415920148 17308373 17451421
MESH:D003928 Diabetic Nephropathies resveratrol 15.0416286809
MESH:D003929 Diabetic Neuropathies Progesterone 3.6017187935
MESH:D003930 Diabetic Retinopathy Sulindac 4.3012861449 17621415
MESH:D003967 Diarrhea Dexamethasone 5.737237001
MESH:D003967 Diarrhea Dinoprostone 5.7310446763 11488427 7237001
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 7.8615619225 19370779 11529661 19085960 12594235 16109766 19164858 16227642 14550746 16081117 18713872 16393943 19420014 11461765 11739529 17562736 16485898 17522070 11743745 15968718 12540782 12392966 19923254 16781746 2444490 10774834 11287661 11834606 12153990 18071297 17906064 14725611 10915739 14986274 10663392 12705907 19739265 19416960 11421492 12958197 16177239
MESH:D056486 Drug-Induced Liver Injury Acetylcysteine 7.8611287661
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 7.8615998439 2869522 17522070 7440962 16227642 10915739 11566570 16177239 19085960 21278145 9327722 19336974 4309450 15027814 6623471 7179309 15968718 7120509 6884620 3732212 10092053 3786805
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 7.8619107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 7.8620420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.1719426721
MESH:D004362 Drug Toxicity Cisplatin 5.7712231392 12649298 15033597 19839026
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 5.7711462148
MESH:D004381 Duodenal Ulcer Tacrolimus 4.2917202747
MESH:D050171 Dyslipidemias Dietary Fats 2.7418367378
MESH:D004417 Dyspnea Albuterol 4.9020016425
MESH:D020821 Dystonic Disorders Nicotine 5.0117881519
MESH:C538011 Eales disease Vitamin E 3.789068938
MESH:D004485 Eczema Dexamethasone 3.5912438553
MESH:D004487 Edema Carrageenan 28.0118449507 17259670 18621150 8985016 16100529 10653021 18841975 15860553 12787963 12083418 12798668
MESH:D004487 Edema Dexamethasone 28.0119703484
MESH:D004487 Edema Mustard Gas 28.019260866 11428647 11402378 11428631
MESH:D004487 Edema pirinixic acid 28.0112083418
MESH:D004487 Edema Raloxifene 28.0115860553
MESH:D004487 Edema resveratrol 28.018985016
MESH:D004487 Edema rosiglitazone 28.0112083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 28.0111000095 12711302
MESH:D004487 Edema Tetradecanoylphorbol Acetate 28.0115177302 11698051 9599246 16716910 8273558 7812673 8113982
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 8.8715322242 16714409 18230668
MESH:D004489 Edema, Cardiac Tretinoin 8.8718230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental ciglitazone 19.6816844232
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 19.6812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 19.6817692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 19.6815845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 19.6817872969
MESH:D016889 Endometrial Neoplasms Estradiol 5.2018566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Tretinoin 5.2016569247
MESH:D004715 Endometriosis celecoxib 15.3015652904
MESH:D004715 Endometriosis Progesterone 15.3016134523
MESH:D004715 Endometriosis Sulindac 15.3015652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 15.3010568697 9294722
MESH:D019446 Endotoxemia Lipopolysaccharides 3.4915328337 17637181 15821434
MESH:D020345 Enterocolitis, Necrotizing resveratrol 3.9617923197
MESH:D004802 Eosinophilia Beclomethasone 7.1210351924
MESH:D004802 Eosinophilia Toluene 2,4-Diisocyanate 7.128156442
MESH:D004890 Erythema Mustard Gas 4.259357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.1916302075
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 5.3416530937
MESH:D004938 Esophageal Neoplasms Cisplatin 5.3416481741 15464296 16785472 15173087 17638652
MESH:D004938 Esophageal Neoplasms Sulindac 5.3412235107
MESH:D017889 Exfoliation Syndrome Homocysteine 4.7916504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 6.4111564622
MESH:D005124 Eye Abnormalities Tretinoin 6.419664655 16938888
MESH:D005128 Eye Diseases Toluene 2,4-Diisocyanate 4.8318447907
MESH:D005234 Fatty Liver Carbon Tetrachloride 33.6512631006 16239168 16045604 61145 15959796 17595544 12795759 19224547
MESH:D005234 Fatty Liver Dietary Fats 33.6519004024 17967931 19551842 18296743
MESH:D005234 Fatty Liver Diethylnitrosamine 33.6520387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 33.6515345470
MESH:D005234 Fatty Liver Iron 33.6516640825
MESH:D005234 Fatty Liver mangiferin 33.6515975614
MESH:D005234 Fatty Liver pirinixic acid 33.6520131406 19236843
MESH:D005234 Fatty Liver Raloxifene 33.6517473493
MESH:D005234 Fatty Liver rosiglitazone 33.6519196556
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.5711858732
MESH:D005334 Fever Dinoprostone 6.9511852909 16997862
MESH:D005334 Fever Lipopolysaccharides 6.9511852909 9205823
MESH:D018221 Fibromatosis, Abdominal Sulindac 4.5714745880
MESH:D018222 Fibromatosis, Aggressive Sulindac 4.2219069698
MESH:D005354 Fibrosarcoma Carrageenan 15.2710962813
MESH:D005354 Fibrosarcoma Methylcholanthrene 15.2710962813 14633661
MESH:D005354 Fibrosarcoma Methylnitrosourea 15.2711555667
MESH:D005355 Fibrosis Albuterol 23.2015467267
MESH:D005355 Fibrosis Carbon Tetrachloride 23.2018705752
MESH:D005355 Fibrosis Dietary Fats 23.2018296743
MESH:D005355 Fibrosis Quercetin 23.2019474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 23.2020067830
MESH:D005355 Fibrosis Tretinoin 23.2017994277
MESH:D005621 Friedreich Ataxia Iron 4.5316640825 16604332
MESH:D005739 Gas Poisoning Albuterol 5.2820016425
MESH:D005756 Gastritis Acetaminophen 2.7516983495
MESH:D005764 Gastroesophageal Reflux Sulindac 4.1411910360
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.0216973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.3716417039
MESH:D005901 Glaucoma Homocysteine 4.4316504073
MESH:D005909 Glioblastoma Quercetin 5.0619804834
MESH:D005909 Glioblastoma Tretinoin 5.0617312396
MESH:D005910 Glioma Methylnitrosourea 4.869825942
MESH:D005910 Glioma Quercetin 4.8617643826
MESH:D005923 Glomerulosclerosis, Focal Segmental pioglitazone 4.4816687628
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.6710696789
MESH:D006086 Graft vs Host Disease Tacrolimus 4.9816376943
MESH:D006130 Growth Disorders Tacrolimus 4.2611041285
MESH:D006261 Headache Nitric Oxide 4.2611284996 11554966
MESH:D006258 Head and Neck Neoplasms Cisplatin 5.6515464296 15102660
MESH:D006258 Head and Neck Neoplasms Tretinoin 5.6516096774
MESH:D034381 Hearing Loss Cisplatin 3.5019898482
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.2316084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.6415464296
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 14.9220471113
MESH:D006330 Heart Defects, Congenital Homocysteine 14.9219638421
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 14.9211294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 14.9214991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin E 14.9216080930
MESH:D006331 Heart Diseases mangiferin 9.0012093613
MESH:D006331 Heart Diseases Raloxifene 9.0011110106
MESH:D006331 Heart Diseases Urethane 9.0016046796
MESH:D006333 Heart Failure pirinixic acid 1.9120558911
MESH:D006402 Hematologic Diseases Benzene 3.8016183116
MESH:D006432 Hemochromatosis Iron 3.7717236123 17053826 16604332 16574947 16640825 17255318
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 8.5816366002
MESH:D006463 Hemolytic-Uremic Syndrome Shiga Toxin 2 8.5816366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.5011000095
MESH:D006486 Hemosiderosis Iron 4.2916604332
MESH:D006505 Hepatitis Carbon Tetrachloride 2.7419110552 19900420
MESH:D006525 Hepatitis, Viral, Human Iron 4.5416640825
MESH:D006527 Hepatolenticular Degeneration Iron 4.0517182432
MESH:D006529 Hepatomegaly Iron 9.4116890145
MESH:D006529 Hepatomegaly pirinixic acid 9.4118467677 16221962 19772884 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 9.4116120746 15340226 12621046
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 4.527520565
MESH:D006548 Hernia, Diaphragmatic Vitamin E 4.5216863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 4.1015709030
MESH:D006561 Herpes Simplex mangiferin 7.2610715843
MESH:D006561 Herpes Simplex resveratrol 7.2616876885
MESH:D051677 Histiocytoma, Malignant Fibrous 1-nitropyrene 6.286692400
MESH:D015658 HIV Infections Iron 3.1216597321
MESH:D006689 Hodgkin Disease Cisplatin 2.8516200630 16170182
MESH:D019584 Hot Flashes Estradiol 7.0017088409
MESH:D019584 Hot Flashes Vitamin E 7.0014716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.1215340226 16959395 16354765 8697196 18606429
MESH:D006930 Hyperalgesia Acetaminophen 16.6116870215
MESH:D006930 Hyperalgesia Dinoprostone 16.6116793879
MESH:D006930 Hyperalgesia Freund's Adjuvant 16.6116769263
MESH:D006930 Hyperalgesia rosiglitazone 16.6112083418
MESH:D006930 Hyperalgesia Tretinoin 16.6116870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.6216899240
MESH:D006937 Hypercholesterolemia Dietary Fats 6.4721332399
MESH:D006937 Hypercholesterolemia resveratrol 6.4717188708
MESH:D006940 Hyperemia Nitric Oxide 4.7011156591
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.6716778211
MESH:D006943 Hyperglycemia kaempferol 11.1218262572
MESH:D006943 Hyperglycemia pirinixic acid 11.1220558911
MESH:D006943 Hyperglycemia Quercetin 11.1211834736 18262572
MESH:D020138 Hyperhomocysteinemia Homocysteine 3.9217292331 18234410 17369066
MESH:D006946 Hyperinsulinism mangiferin 4.229881663 11315760
MESH:D006949 Hyperlipidemias Dietary Fats 10.7321332399
MESH:D006949 Hyperlipidemias mangiferin 10.7315975614
MESH:D006949 Hyperlipidemias resveratrol 10.7316873680
MESH:D006967 Hypersensitivity Butylated Hydroxytoluene 14.2817604070
MESH:D006967 Hypersensitivity fexofenadine 14.2817910814
MESH:D006967 Hypersensitivity mangiferin 14.2816536907
MESH:D006967 Hypersensitivity Toluene 2,4-Diisocyanate 14.2810880147 11019492
MESH:D006973 Hypertension Benzene 11.4617940673
MESH:D006973 Hypertension Dexamethasone 11.4617042910
MESH:D006973 Hypertension Quercetin 11.4618356687
MESH:D006973 Hypertension Raloxifene 11.4615787275 17577099
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 11.4618850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.2015338365
MESH:D006976 Hypertension, Pulmonary Nitric Oxide 3.7215838368
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.4917488730
MESH:D007006 Hypogonadism Iron 3.7016640825
MESH:C537153 Hypomagnesemia primary Tacrolimus 5.2411041285
MESH:D007021 Hypospadias Ethinyl Estradiol 2.9216945680 16569931
MESH:D007022 Hypotension Tacrolimus 4.2811041285
MESH:D007037 Hypothyroidism Iron 4.1916640825
MESH:D007154 Immune System Diseases mangiferin 4.9316076520
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 8.5315869954
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 8.5317600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.6112013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 7.4317937319
MESH:D007248 Infertility, Male Methylnitrosourea 7.437193160
MESH:D007248 Infertility, Male vinclozolin 7.4316467254
MESH:D007249 Inflammation Carrageenan 51.357907874 10653021 16100529 18295198 12798668 12428691 12787963 19934399 8985016
MESH:D007249 Inflammation Cilomilast 51.3516956605 17155857
MESH:D007249 Inflammation Dexamethasone 51.3511099482 8960868
MESH:D007249 Inflammation Dietary Fats 51.3520412841
MESH:D007249 Inflammation Diethylnitrosamine 51.3518785209
MESH:D007249 Inflammation Flavonoids 51.3517296493
MESH:D007249 Inflammation Freund's Adjuvant 51.3516793879
MESH:D007249 Inflammation Lipopolysaccharides 51.3517963957 9205823 17255318 12878042 17237260
MESH:D007249 Inflammation mangiferin 51.3515222974
MESH:D007249 Inflammation Mustard Gas 51.359260866 11428631 17524151 11428647 8975870 11402378 11428620 16001271 9357497
MESH:D007249 Inflammation pioglitazone 51.3516908763
MESH:D007249 Inflammation Progesterone 51.3515869954
MESH:D007249 Inflammation resveratrol 51.3516366677
MESH:D007249 Inflammation rosiglitazone 51.3512083418
MESH:D007249 Inflammation Sulindac 51.353291741
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 51.3512200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 51.3515177302 8273558 7562506 7812673 11698051
MESH:D015212 Inflammatory Bowel Diseases Leukotriene B4 4.0011006272
MESH:D007251 Influenza, Human Nordihydroguaiaretic Acid 25.3818473937
MESH:D007251 Influenza, Human pyrrolidine dithiocarbamic acid 25.3818473937
MESH:D007251 Influenza, Human Quercetin 25.3816624496
MESH:D007251 Influenza, Human resveratrol 25.3816624496
MESH:D007251 Influenza, Human Vitamin E 25.3816624496
MESH:D007333 Insulin Resistance Dietary Fats 16.1811836018 18457598
MESH:D007333 Insulin Resistance Estradiol 16.1816627594 16393666
MESH:D007333 Insulin Resistance mangiferin 16.1811315760
MESH:D007333 Insulin Resistance pirinixic acid 16.1816306350
MESH:D007333 Insulin Resistance rosiglitazone 16.1816306350
MESH:D007410 Intestinal Diseases Nitric Oxide 7.1711574821 11713966 10210152
MESH:D007410 Intestinal Diseases Tretinoin 7.1717994277
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 7.5610783313
MESH:D007414 Intestinal Neoplasms Sulindac 7.5612584176 10223192 10213222 12351151 12628509 12663524
MESH:D007417 Intestinal Polyps Sulindac 4.1312394442 11245490
MESH:D002532 Intracranial Aneurysm Reactive Oxygen Species 4.1919381132
MESH:D019189 Iron Metabolism Disorders Iron 8.7617163184
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 8.7617255318
MESH:D007511 Ischemia mangiferin 4.3816806951
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 7.1716580747
MESH:D007569 Jaw Abnormalities Tretinoin 7.1715992940 17551590
MESH:D007627 Keloid Quercetin 4.0617086741
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.2115464296
MESH:D007674 Kidney Diseases Acetaminophen 27.0915629191 12587719
MESH:D007674 Kidney Diseases Acrolein 27.0912488133
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 27.0915369732
MESH:D007674 Kidney Diseases Cisplatin 27.0915190930 19839026 12649298 12231392 18289764
MESH:D007674 Kidney Diseases Estradiol 27.0915618244
MESH:D007674 Kidney Diseases mangiferin 27.0912093613
MESH:D007674 Kidney Diseases Quercetin 27.0916962696
MESH:D007674 Kidney Diseases Tacrolimus 27.0911041285
MESH:D007674 Kidney Diseases Vitamin E 27.0912488133
MESH:D007680 Kidney Neoplasms Estradiol 2.2415610895
MESH:D007683 Kidney Tubular Necrosis, Acute Calcium 8.8216316344
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 8.8211231351
MESH:D007859 Learning Disorders mangiferin 4.0719182383
MESH:D007889 Leiomyoma Raloxifene 3.6416973256
MESH:D007896 Leishmaniasis Nitric Oxide 3.8717218153
MESH:D007938 Leukemia Benzene 10.4717119257 18335105 15935818 14694614
MESH:D007938 Leukemia kaempferol 10.4717468513
MESH:D007938 Leukemia Quercetin 10.4717468513
MESH:D007938 Leukemia Tretinoin 10.4717143497
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive mangiferin 3.9015498116
MESH:D007951 Leukemia, Myeloid Benzene 6.9317506065
MESH:D007951 Leukemia, Myeloid Tretinoin 6.9316932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute Benzene 3.2219478238
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.2216294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 9.0216766008
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 9.0216087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 9.0217339181 15748426 19642359 16331271 17217047 16935935 16140955 12679006 19035177 16766008 16823087 17506722 16891316 19029980 17294898 17301526 17649720 17368321 17712046 19225113 17107899 16788101 9834237 19075265 17361223
MESH:D007970 Leukopenia Lipopolysaccharides 3.7915821434
MESH:D020961 Lewy Body Disease Iron 4.5316563566
MESH:D007984 Leydig Cell Tumor vinclozolin 3.8216417039
MESH:D017880 Limb Deformities, Congenital Methylnitrosourea 6.1015526292
MESH:D017880 Limb Deformities, Congenital Tretinoin 6.109224671
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.8917334410 17157831 16239168 16943688 11408273 21278145 11903743 17174718 16221502
MESH:D008103 Liver Cirrhosis Dietary Fats 10.8918296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 10.8920032147 18407596 18665156 19638242 18522880
MESH:D008103 Liver Cirrhosis Iron 10.8916640825
MESH:D008105 Liver Cirrhosis, Biliary Sulindac 3.5812468960
MESH:D008106 Liver Cirrhosis, Experimental 1,3-dimethylthiourea 22.7911682029
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 22.7912741479 14716833 12632512 14512876 16248980 18481824 12958196 16033810 17631135 15370692 18339082 16097048 15123356 12445421 17766677 18395095 18210741 14620537 15996030 18166357 16192424 12445418 17708605 13678700 12586293 12666154 18187930 18705752 15338365 17640975 17761835 15057751 15362042 18156304 17805973 15876570 16638106 16015684 17869086 18054572 18472332 17900296 17481882 12667390 14748882 18006644 12898905 18429990 12632514 11481614 16136751 18420326 18277467 16116963 15730626 14716496 18472094 17525996 12649538 12609069 12546737 17976157 18251166 18263696 15673190 15893842 18376398 18279442 18395914 17944888 17698563 18205269 18412020 17565644 17714472 18317297 15931870 15052691 17557913 15959796 12389079 15925388 15818738 16011737 17922224 16027843 18418968 17721639 10355542 17823541 20821823 14724832 15650968
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 22.7916718785
MESH:D008106 Liver Cirrhosis, Experimental Dinoprostone 22.7915816358
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 22.7914659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 22.7912878042
MESH:D008106 Liver Cirrhosis, Experimental pioglitazone 22.7916484506 15052691
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 22.7915474484
MESH:D008106 Liver Cirrhosis, Experimental pyrrolidine dithiocarbamic acid 22.7915078482
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 22.7912741479
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 22.7917347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 22.7912878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 22.7916248980 18397230
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 22.7916169303
MESH:D008107 Liver Diseases Acetaminophen 8.7119014921 16610002 19460945 16611625 12969438 19784758 12587719 11587558
MESH:D008107 Liver Diseases Carbon Tetrachloride 8.7115830285 16246199 15720792 17285989 16964402
MESH:D008107 Liver Diseases Diethylnitrosamine 8.7117034775
MESH:D008107 Liver Diseases Dinoprostone 8.7115816358
MESH:D008107 Liver Diseases Sulindac 8.7116867024 14986274
MESH:D008108 Liver Diseases, Alcoholic Iron 4.1217207112 16737972
MESH:D017093 Liver Failure Carbon Tetrachloride 3.2715123358
MESH:D017114 Liver Failure, Acute Acetaminophen 6.7116871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 6.7116899240 14706259
MESH:D008113 Liver Neoplasms 9,10-Dimethyl-1,2-benzanthracene 27.419643874
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 27.4120195826 21137059
MESH:D008113 Liver Neoplasms Butylated Hydroxytoluene 27.4118177683
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 27.4119294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 27.4121047994 21278145 9163691 19426721 19090486 19690152 20492335 12112319 20434301 20452335 20501860 20137499 18644402 12771043 19850985 19499222 16942905 19294768 19812893 19638242 19073162 20118626 20405173 18977376 19551842 19642983 18754104 21071580 10737359 21167192 15885732 15175105 19427195 20583210 2422723 18648771 19256749 2862719 19833225 19255062 19254457 20101389 18978307 19996281
MESH:D008113 Liver Neoplasms Iron 27.4120302851 16640825
MESH:D008113 Liver Neoplasms pirinixic acid 27.4120007298 15890375 16377806
MESH:D008113 Liver Neoplasms Quercetin 27.4118980244
MESH:D008113 Liver Neoplasms resveratrol 27.4119321006 19812893 20405173 19073162
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 27.4116984957
MESH:D008113 Liver Neoplasms Urethane 27.4116391232 17559639 17093202
MESH:D008114 Liver Neoplasms, Experimental 9,10-Dimethyl-1,2-benzanthracene 22.021399818
MESH:D008114 Liver Neoplasms, Experimental Benzene 22.0212562636
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 22.0215583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 22.0216267830 18775883 19539802 18079962 19009564 18544905 9362446 18253720 19519916 17854601 18308698 19126423 21159647 18093689 17174075 19004024 16842330 2563599 18282651 17942915 18164116 3124819
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 22.02598648 1399818
MESH:D008114 Liver Neoplasms, Experimental Polychlorinated Biphenyls 22.021423854
MESH:D008114 Liver Neoplasms, Experimental Quercetin 22.0219519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 22.0212151625
MESH:D038061 Lower Extremity Deformities, Congenital Methylnitrosourea 4.5716080182
MESH:D008171 Lung Diseases Acetylcysteine 20.0612815614
MESH:D008171 Lung Diseases Acrolein 20.0611504702
MESH:D008171 Lung Diseases Asbestos, Serpentine 20.0617200189
MESH:D008171 Lung Diseases Mustard Gas 20.0618702808 18161513
MESH:D008171 Lung Diseases Ozone 20.0619066396 8266340
MESH:D008171 Lung Diseases Vitamin E 20.0616863852
MESH:D017563 Lung Diseases, Interstitial Benzene 3.8914698565
MESH:D055370 Lung Injury Lipopolysaccharides 14.4921114838
MESH:D055370 Lung Injury Nitric Oxide 14.4911395602
MESH:D055370 Lung Injury Ozone 14.4920417186
MESH:D055370 Lung Injury pyrrolidine dithiocarbamic acid 14.4916129981
MESH:D008175 Lung Neoplasms 9,10-Dimethyl-1,2-benzanthracene 47.0411376689
MESH:D008175 Lung Neoplasms Asbestos, Serpentine 47.0411198217
MESH:D008175 Lung Neoplasms Benzene 47.0412562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 47.046695378 18816296 18520028 20464547 20135361 18569708 17053015 20064080 20869020
MESH:D008175 Lung Neoplasms Butylated Hydroxytoluene 47.0416337739 18597497 11246140 15390079 11696405 19925653 19359593
MESH:D008175 Lung Neoplasms ciglitazone 47.0415899809
MESH:D008175 Lung Neoplasms Cisplatin 47.0411798837 17225452 6189445
MESH:D008175 Lung Neoplasms Dexamethasone 47.0415824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 47.0420970405 20512841 6695378 21163286
MESH:D008175 Lung Neoplasms Iron 47.0416640825
MESH:D008175 Lung Neoplasms Isotretinoin 47.0415899809
MESH:D008175 Lung Neoplasms mangiferin 47.0418520028 18816296 18569708
MESH:D008175 Lung Neoplasms Methylcholanthrene 47.0411893704 16271038 10545420 20970405 17909032 7750092 15390079 9230183 21163286 16337739 20512841 6695378 1399818
MESH:D008175 Lung Neoplasms Methylnitrosourea 47.0418062963
MESH:D008175 Lung Neoplasms Mustard Gas 47.048781369 3148597
MESH:D008175 Lung Neoplasms Ozone 47.048597069 7614698
MESH:D008175 Lung Neoplasms Quercetin 47.0416280456
MESH:D008175 Lung Neoplasms Sulindac 47.0415713900 19359593
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 47.0419555203 11884234
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 47.0411807781
MESH:D008175 Lung Neoplasms Urethane 47.0411544531 17255336 6695378 15136453 16391232 11552296 15902970 11992545 7750092 16337739 12466968 11062179 11246140 17195641 10822126 16204055 10779650 11074608 16289808 10530776 15166089 16788158 16926031 16007126 11893704 11307925 11323394 17093202 12957351 11497255 10997738 12765245 14587096 12117781 11807781
MESH:D008175 Lung Neoplasms Vehicle Emissions 47.049255578
MESH:D008175 Lung Neoplasms Vitamin E 47.0411062179
MESH:D008223 Lymphoma 9,10-Dimethyl-1,2-benzanthracene 12.2811376689
MESH:D008223 Lymphoma Benzene 12.2817119257 17584886
MESH:D008223 Lymphoma Methylnitrosourea 12.2811418001 16257854
MESH:D008223 Lymphoma Nitric Oxide 12.2816166326
MESH:D016393 Lymphoma, B-Cell Methylnitrosourea 7.7214633661
MESH:D016393 Lymphoma, B-Cell resveratrol 7.7217088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.1014749477
MESH:D008268 Macular Degeneration Iron 3.3916640825
MESH:D015674 Mammary Neoplasms, Animal Benzene 7.2612562636
MESH:D015674 Mammary Neoplasms, Animal resveratrol 7.2615688416
MESH:D008325 Mammary Neoplasms, Experimental 1-nitropyrene 33.546692400
MESH:D008325 Mammary Neoplasms, Experimental 9,10-Dimethyl-1,2-benzanthracene 33.5410697514 1500032 16153821 18840765 11807958 8985016 12844480 16082771
MESH:D008325 Mammary Neoplasms, Experimental Benzene 33.5411921183
MESH:D008325 Mammary Neoplasms, Experimental Butylated Hydroxytoluene 33.541500032
MESH:D008325 Mammary Neoplasms, Experimental celecoxib 33.5412104042 19196722
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 33.5417203775 11408345 16891317 11807958
MESH:D008325 Mammary Neoplasms, Experimental Methylnitrosourea 33.5414999141 16619500 16051031 10767621 19196723 15313902 16944150 15688392 11807958 17131329 11751437 12931682 16827153 17020996 15113128 14633655 10838139
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 33.5411408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 33.5411606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 33.5416827153
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 33.548985016
MESH:D020149 Manganese Poisoning Estradiol 3.5619453300
MESH:D008527 Medulloblastoma Tretinoin 2.3217453147
MESH:D008545 Melanoma Cisplatin 13.5512374674 11135225 12393984 16248763 18505091 17023156 16809738 17761969 16432458 18332650 18176117 15577323 12883367
MESH:D008545 Melanoma Dinitrochlorobenzene 13.5512202904 17334785
MESH:D008545 Melanoma Isotretinoin 13.5517237267
MESH:D008545 Melanoma Reactive Oxygen Species 13.5517992120
MESH:D008545 Melanoma resveratrol 13.5517992120
MESH:D008545 Melanoma Sulindac 13.5516642371
MESH:D008545 Melanoma Tretinoin 13.5516752155
MESH:D008545 Melanoma Vitamin K 3 13.5519082730
MESH:D018328 Melanoma, Amelanotic Cisplatin 3.8715990972
MESH:D008546 Melanoma, Experimental Acetaminophen 8.0319513568
MESH:D008546 Melanoma, Experimental Acrolein 8.0310803710
MESH:D008569 Memory Disorders mangiferin 4.0719182383
MESH:D008591 Meningomyelocele Homocysteine 9.4616602021
MESH:D008591 Meningomyelocele Tretinoin 9.4616940565
MESH:D008654 Mesothelioma Cisplatin 2.7917638057
MESH:D008659 Metabolic Diseases resveratrol 3.5417112576
MESH:D024821 Metabolic Syndrome X rosiglitazone 3.6017261469
MESH:D008679 Metaplasia Ozone 4.1810496685
MESH:D008881 Migraine Disorders Nitric Oxide 3.5911701602
MESH:D020326 Migraine without Aura Dinoprostone 8.3211304026
MESH:D020326 Migraine without Aura Nitric Oxide 8.3214659530 11304026
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 4.6315863610
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.4516381670
MESH:D009101 Multiple Myeloma Benzene 15.2817119195
MESH:D009101 Multiple Myeloma celecoxib 15.2816123214
MESH:D009101 Multiple Myeloma Dexamethasone 15.2816118317 15744524 15867202
MESH:D009101 Multiple Myeloma Raloxifene 15.2816497877
MESH:D009101 Multiple Myeloma resveratrol 15.2817049120 16267019 14749477 16490592 17164350 17935668
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 4.7417086897
MESH:D009134 Muscular Atrophy, Spinal resveratrol 3.9617962980
MESH:D009135 Muscular Diseases pirinixic acid 2.6216239165
MESH:D009181 Mycoses Iron 4.5416640825
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 5.509809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 5.5017596541
MESH:D009203 Myocardial Infarction Homocysteine 12.6717412321
MESH:D009203 Myocardial Infarction mangiferin 12.6716584858 16697266 19172585 17052832 16538859
MESH:D009203 Myocardial Infarction pirinixic acid 12.6719151258
MESH:D009203 Myocardial Infarction Quercetin 12.6719595682
MESH:D009203 Myocardial Infarction resveratrol 12.6716317513 17015251 17125593 17188708 16525036 16456233
MESH:D017202 Myocardial Ischemia Iron 10.9816604332
MESH:D017202 Myocardial Ischemia resveratrol 10.9817015251 17125593
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 10.9812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 14.2716810080
MESH:D015428 Myocardial Reperfusion Injury Iron 14.2716604332
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 14.2716411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 14.2719207477
MESH:D009205 Myocarditis resveratrol 3.8517322642
MESH:D009232 Myxoma Raloxifene 4.6316343187
MESH:D009362 Neoplasm Metastasis Acetylcysteine 7.0214720322
MESH:D009362 Neoplasm Metastasis clopidogrel 7.0211875746
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 7.029029167 3581430
MESH:D009369 Neoplasms 9,10-Dimethyl-1,2-benzanthracene 25.2711544531
MESH:D009369 Neoplasms Acrolein 25.2717329238
MESH:D009369 Neoplasms Benzo(a)pyrene 25.2711141357
MESH:D009369 Neoplasms Cisplatin 25.2716773208
MESH:D009369 Neoplasms Methylnitrosourea 25.2715533788
MESH:D009369 Neoplasms Nicotine 25.2716365874
MESH:D009369 Neoplasms pirinixic acid 25.2717405874
MESH:D009369 Neoplasms Quercetin 25.2715185748
MESH:D009369 Neoplasms Tretinoin 25.2716946489 16594593
MESH:D009369 Neoplasms Urethane 25.2715625555
MESH:D009374 Neoplasms, Experimental Asbestos, Serpentine 19.2511704859
MESH:D009374 Neoplasms, Experimental Methylnitrosourea 19.2512696579
MESH:D009374 Neoplasms, Experimental resveratrol 19.258985016
MESH:D009374 Neoplasms, Experimental Toluene 2,4-Diisocyanate 19.251670384
MESH:D009374 Neoplasms, Experimental Urethane 19.2515582191
MESH:D009376 Neoplasms, Hormone-Dependent celecoxib 4.5119196722
MESH:D009389 Neovascularization, Pathologic Estradiol 7.3717289903
MESH:D009389 Neovascularization, Pathologic Nicotine 7.3716365874
MESH:D009393 Nephritis Acrolein 5.3612653641
MESH:D009395 Nephritis, Interstitial Cisplatin 3.5815464296
MESH:D009404 Nephrotic Syndrome Iron 3.7217178036
MESH:D009410 Nerve Degeneration mangiferin 3.8817433543
MESH:D009421 Nervous System Malformations Estradiol 11.3311399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 11.3314600291
MESH:D009421 Nervous System Malformations Tretinoin 11.339125849
MESH:D009436 Neural Tube Defects Acetylcysteine 8.4919446573
MESH:D009436 Neural Tube Defects Benzene 8.4915643154
MESH:D009436 Neural Tube Defects Tretinoin 8.499142499
MESH:D009442 Neurilemmoma Methylnitrosourea 4.5711555667
MESH:D009447 Neuroblastoma Cisplatin 5.538761367
MESH:D009447 Neuroblastoma Isotretinoin 5.5317368321
MESH:D019636 Neurodegenerative Diseases Acetaminophen 27.7418514411
MESH:D019636 Neurodegenerative Diseases Acrolein 27.7411342003
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 27.7420387270
MESH:D019636 Neurodegenerative Diseases Iron 27.7416604332 17296847
MESH:D019636 Neurodegenerative Diseases resveratrol 27.7417652729
MESH:D019636 Neurodegenerative Diseases Sulindac 27.7416850258 17266991
MESH:D019636 Neurodegenerative Diseases Tacrolimus 27.7415081597
MESH:D017599 Neuroectodermal Tumors Cisplatin 3.798761367
MESH:D020078 Neurogenic Inflammation Quercetin 7.8717929310
MESH:D020078 Neurogenic Inflammation resveratrol 7.8717929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.1920387270
MESH:D009503 Neutropenia Leukotriene B4 7.108305713
MESH:D009503 Neutropenia Mustard Gas 7.107688884 16761898
MESH:D009765 Obesity Dietary Fats 3.3117217161 16723640 20518802 11836018 18457598 21332399 18674790 20132043 19632207
MESH:D009765 Obesity pirinixic acid 3.3120558911
MESH:D009784 Occupational Diseases Benzene 6.9517119257 15576619 15727169 17479406 16737584 15935809 15913788 17178637 15612468
MESH:D009784 Occupational Diseases Toluene 2,4-Diisocyanate 6.956091945 3040596 12585506 18394133 11077013 8156442 6091946
MESH:D010003 Osteoarthritis Iron 3.3416640825
MESH:D010005 Osteoarthropathy, Secondary Hypertrophic Dinoprostone 5.5518500342
MESH:D010024 Osteoporosis Calcium 11.7717882678
MESH:D010024 Osteoporosis Iron 11.7716640825 16648989
MESH:D010024 Osteoporosis kaempferol 11.7716756079
MESH:D010024 Osteoporosis Raloxifene 11.7717882678 19059307 15775268
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 12.0219495926
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 12.0215579764 17893378 15758505 17823083
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 12.0217513867
MESH:D010051 Ovarian Neoplasms 9,10-Dimethyl-1,2-benzanthracene 23.2716891317
MESH:D010051 Ovarian Neoplasms Benzene 23.2712562636
MESH:D010051 Ovarian Neoplasms CD 437 23.2717474084
MESH:D010051 Ovarian Neoplasms Cisplatin 23.2717225452 15464296 19769630 6897625
MESH:D010051 Ovarian Neoplasms Estradiol 23.2719401270
MESH:D010051 Ovarian Neoplasms Progesterone 23.2716525653 17393432
MESH:D010051 Ovarian Neoplasms Quercetin 23.2719005980
MESH:D010051 Ovarian Neoplasms Tretinoin 23.2716936753
MESH:D010051 Ovarian Neoplasms Urethane 23.2716391232
MESH:D010146 Pain Acetaminophen 6.9516870215
MESH:D010146 Pain Sulindac 6.953291741
MESH:D010146 Pain Tretinoin 6.9516870215
MESH:D010190 Pancreatic Neoplasms Cisplatin 21.4519003803
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 21.4516540662
MESH:D010190 Pancreatic Neoplasms Methylnitrosourea 21.4516965848
MESH:D010190 Pancreatic Neoplasms Quercetin 21.4516965848
MESH:D010190 Pancreatic Neoplasms Reactive Oxygen Species 21.4515580305
MESH:D010190 Pancreatic Neoplasms Sulindac 21.4511504793 16820089
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 21.4515976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 21.4515976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 2.8311578682
MESH:D010212 Papilloma 9,10-Dimethyl-1,2-benzanthracene 10.8317234724 15173996 16517061
MESH:D010212 Papilloma Iron 10.8312065085
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 10.8318404319 12065085 8330346 18922899
MESH:D020447 Parasomnias Iron 5.0917352947
MESH:D010300 Parkinson Disease Acrolein 11.5017690948
MESH:D010300 Parkinson Disease Homocysteine 11.5016275827
MESH:D010300 Parkinson Disease Iron 11.5016640825 16563566
MESH:D010300 Parkinson Disease mangiferin 11.5017433543
MESH:D010300 Parkinson Disease Polychlorinated Biphenyls 11.5016702228
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.3212520081
MESH:D010518 Periodontitis mangiferin 4.6819026997
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.4515464296
MESH:D010538 Peritonitis Ozone 7.7916369182
MESH:D010538 Peritonitis Thioglycolates 7.7919804847 19180231 16751407 15707874 18628355 11985352 19641140
MESH:D010787 Photosensitivity Disorders Acrolein 4.8111550810
MESH:D010900 Pituitary Diseases Iron 4.7416604332
MESH:D010911 Pituitary Neoplasms Urethane 4.5216391232
MESH:D010995 Pleural Diseases Asbestos, Serpentine 4.8010923243
MESH:D010997 Pleural Neoplasms Cisplatin 4.4217638057
MESH:D010998 Pleurisy Carrageenan 5.8219934399
MESH:D011014 Pneumonia Butylated Hydroxytoluene 13.4511893704
MESH:D011014 Pneumonia Lipopolysaccharides 13.4512224865 11605937
MESH:D011014 Pneumonia Ozone 13.4518007984 18381685 18929643
MESH:D011015 Pneumonia, Aspiration Nitric Oxide 4.4318573544
MESH:D011041 Poisoning Iron 6.2116604332
MESH:D011041 Poisoning Mustard Gas 6.2115727166
MESH:D017119 Porphyria Cutanea Tarda Iron 8.1316640825
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 8.1318163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 6.592563599
MESH:D011230 Precancerous Conditions Quercetin 6.5919056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 2.9521297632
MESH:D011225 Pre-Eclampsia Iron 3.6816640825
MESH:D011297 Prenatal Exposure Delayed Effects Isotretinoin 15.9418769834
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 15.9416679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 15.9411222880 11896295 11399792 11118676
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 15.9418220299 18042343 19015723
MESH:D011469 Prostatic Diseases vinclozolin 4.0218220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.0520887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.8617292933
MESH:D011471 Prostatic Neoplasms celecoxib 3.8615570007 17908994
MESH:D011471 Prostatic Neoplasms Estradiol 3.8616740699
MESH:D011471 Prostatic Neoplasms Hyaluronic Acid 3.8616864594
MESH:D011471 Prostatic Neoplasms Methylnitrosourea 3.8612376480 15682402
MESH:D011471 Prostatic Neoplasms Nordihydroguaiaretic Acid 3.8618491370
MESH:D011471 Prostatic Neoplasms Polychlorinated Biphenyls 3.8615721890
MESH:D011471 Prostatic Neoplasms pyrrolidine dithiocarbamic acid 3.8616139439
MESH:D011471 Prostatic Neoplasms Quercetin 3.8617292933 14715546
MESH:D011471 Prostatic Neoplasms Raloxifene 3.8616536755 16220300 15731164
MESH:D011471 Prostatic Neoplasms resveratrol 3.8617675339 17718901 15767336 16731767 17636462 17804756
MESH:D011471 Prostatic Neoplasms Vitamin E 3.8615084515
MESH:D011472 Prostatitis vinclozolin 4.0218629315
MESH:D011507 Proteinuria pioglitazone 6.8816687628
MESH:D011507 Proteinuria Tretinoin 6.8816636307
MESH:D011528 Protozoan Infections Iron 5.0916640825
MESH:D011537 Pruritus Ethinyl Estradiol 11.1515861022 16919318
MESH:D011537 Pruritus fexofenadine 11.1517133778
MESH:D011537 Pruritus Mustard Gas 11.1518058305
MESH:D011565 Psoriasis Leukotriene B4 3.9211006272
MESH:D011596 Psychomotor Disorders Isotretinoin 5.0118769834
MESH:D011625 Pterygium Tretinoin 3.8816723453
MESH:D011657 Pulmonary Eosinophilia Toluene 2,4-Diisocyanate 4.7014606601
MESH:D011658 Pulmonary Fibrosis marker/mechanism 17620002
MESH:D011658 Pulmonary Fibrosis Asbestos, Serpentine 4.6718569384 15511213
MESH:D011658 Pulmonary Fibrosis Mustard Gas 4.6710334151 17894541 17720292 17266442 17620002
MESH:D011693 Purpura Raloxifene 4.6315770314
MESH:D011833 Radiation Injuries, Experimental mangiferin 5.4815830843
MESH:D051437 Renal Insufficiency Acrolein 7.7212732208
MESH:D051437 Renal Insufficiency Cisplatin 7.7215464296
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.6516325855
MESH:D015427 Reperfusion Injury pirinixic acid 4.7419058328
MESH:D015427 Reperfusion Injury resveratrol 4.7416317513 16314181 15827377 17520802 17058453
MESH:D012120 Respiration Disorders Cilomilast 5.7417155857
MESH:D012128 Respiratory Distress Syndrome, Adult Acetylcysteine 10.6012210543
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 10.6018379247 11700416
MESH:D012128 Respiratory Distress Syndrome, Adult pyrrolidine dithiocarbamic acid 10.6016129981
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 6.3910835634
MESH:D012130 Respiratory Hypersensitivity Toluene 2,4-Diisocyanate 6.397692837 20219652 16940033
MESH:D012135 Respiratory Sounds Vehicle Emissions 4.3418950799
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 2.9618990726
MESH:D012140 Respiratory Tract Diseases Toluene 2,4-Diisocyanate 4.2018447907
MESH:D012148 Restless Legs Syndrome Iron 3.8216930377
MESH:D012162 Retinal Degeneration Methylnitrosourea 3.6918155124 18172121
MESH:D012170 Retinal Vein Occlusion clopidogrel 5.2319371211
MESH:D012175 Retinoblastoma Methylnitrosourea 4.5711555667
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.2516283617 16116481
MESH:D012220 Rhinitis Beclomethasone 7.1310351924
MESH:D012220 Rhinitis Toluene 2,4-Diisocyanate 7.1319050374
MESH:D012221 Rhinitis, Allergic, Perennial Toluene 2,4-Diisocyanate 4.3612617775 15015336
MESH:D006255 Rhinitis, Allergic, Seasonal Toluene 2,4-Diisocyanate 4.5919075512
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.4318045962
MESH:D012512 Sarcoma, Ewing's Cisplatin 3.5614601052
MESH:D012554 Schistosomiasis japonica Quercetin 4.6216862918
MESH:D012555 Schistosomiasis mansoni Nitric Oxide 4.589673227
MESH:D012559 Schizophrenia Homocysteine 2.9516641680
MESH:D012640 Seizures Nicotine 3.1917873105
MESH:D012772 Shock, Septic mangiferin 4.3315177305
MESH:D012852 Sinusitis Beclomethasone 5.517327846
MESH:D012871 Skin Diseases Mustard Gas 3.8616961503 15451306 12880345
MESH:D012871 Skin Diseases Vitamin E 3.8618709164
MESH:D012878 Skin Neoplasms 9,10-Dimethyl-1,2-benzanthracene 26.408985016 15173996 11376689 16517061
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 26.4010029692 19755658
MESH:D012878 Skin Neoplasms Iron 26.4012065085
MESH:D012878 Skin Neoplasms resveratrol 26.408985016 15837718
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 26.408532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 26.4016192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 26.4018404319 12065085 8330346 11807781 8985016
MESH:D012878 Skin Neoplasms Tretinoin 26.4016467112
MESH:D012878 Skin Neoplasms Urethane 26.4011807781
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.4215464296
MESH:D012912 Sneezing Toluene 2,4-Diisocyanate 4.5919075512 19050374
MESH:D013088 Spermatocele Ethinyl Estradiol 3.0216709447
MESH:D013119 Spinal Cord Injuries Progesterone 3.3716503802 15862959
MESH:D013272 Stomach Diseases Dexamethasone 3.4215472012
MESH:D013274 Stomach Neoplasms Benzene 7.7312562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 7.7320155912 2093021
MESH:D013274 Stomach Neoplasms celecoxib 7.7315609394
MESH:D013274 Stomach Neoplasms Cisplatin 7.7317522103 18396642 15958060
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 7.7318456281
MESH:D013274 Stomach Neoplasms Methylnitrosourea 7.7318593901 15930296 16257854
MESH:D013274 Stomach Neoplasms Tretinoin 7.7317261132
MESH:D013276 Stomach Ulcer Acetylcysteine 14.0417918041
MESH:D013276 Stomach Ulcer Dexamethasone 14.0415138204
MESH:D013276 Stomach Ulcer fucoidan 14.0418209962 15138204
MESH:D013276 Stomach Ulcer mangiferin 14.0417918041
MESH:D013276 Stomach Ulcer Nitric Oxide 14.0415138204
MESH:D020521 Stroke Acrolein 10.1716269634
MESH:D020521 Stroke Raloxifene 10.1716837676
MESH:D020521 Stroke Vitamin E 10.1716517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.6616321402
MESH:D013398 Sudden Infant Death Iron 4.5416640825
MESH:D013736 Testicular Neoplasms Cisplatin 3.7815464296 17225452
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.3615821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.7711994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.3715669648
MESH:D013953 Thymus Neoplasms Benzene 9.2110850423
MESH:D013953 Thymus Neoplasms Methylnitrosourea 9.2111418001
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 2.9812697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 7.867505956
MESH:D013964 Thyroid Neoplasms Methylnitrosourea 7.863078959 7505956
MESH:D013964 Thyroid Neoplasms Tretinoin 7.8617045167 16026305
MESH:D013978 Tibial Fractures Estradiol 10.6419048282
MESH:D013978 Tibial Fractures Raloxifene 10.6419048282
OMIM:188890 TOBACCO ADDICTION, SUSCEPTIBILITY TO Nicotine 4.0116720336 11259349 16785264
MESH:D014029 Tobacco Use Disorder Nicotine 4.5615735609 18305452 18041664 17979512
MESH:D014062 Tongue Neoplasms resveratrol 7.2116227395
MESH:D014062 Tongue Neoplasms Tretinoin 7.2116051514
MESH:D014235 Trichinellosis mangiferin 5.1314669257
MESH:D014376 Tuberculosis Iron 6.0216597321
MESH:D014376 Tuberculosis Tretinoin 6.0216040207
MESH:D001749 Urinary Bladder Neoplasms 2-Naphthylamine 16.8611144890
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 16.8617053015
MESH:D001749 Urinary Bladder Neoplasms CD 437 16.8616720286
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 16.8612973940 15464296 17225452
MESH:D001749 Urinary Bladder Neoplasms Quercetin 16.8616720314
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 16.8617572228
MESH:D001749 Urinary Bladder Neoplasms Vehicle Emissions 16.8611144890
MESH:D014581 Urticaria Acetaminophen 2.1410982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 11.2716803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 11.2717473185
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 11.2716129372
MESH:D014594 Uterine Neoplasms Benzene 20.9312562636
MESH:D014594 Uterine Neoplasms celecoxib 20.9318645019
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 20.9314692618
MESH:D014594 Uterine Neoplasms resveratrol 20.9317044934
MESH:D014594 Uterine Neoplasms Sulindac 20.9318645019
MESH:D014604 Uveal Neoplasms Tretinoin 3.6816752155
MESH:D014605 Uveitis Dexamethasone 3.891336536
MESH:D014625 Vaginal Neoplasms Cisplatin 3.7215577323
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.6712125929
MESH:D019043 Vascular Neoplasms Urethane 4.9810620525
MESH:D020301 Vasospasm, Intracranial Nitric Oxide Donors 5.2419057314
MESH:D054556 Venous Thromboembolism Raloxifene 4.2816837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.7114671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 3.4217488730
MESH:D014820 Vitiligo Tretinoin 3.1916761959
MESH:D014839 Vomiting Cisplatin 3.8011897121
MESH:D014846 Vulvar Neoplasms Raloxifene 4.6316343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.3215886252
MESH:D015430 Weight Gain Dietary Fats 2.9516723640
MESH:D009396 Wilms Tumor Tretinoin 3.1716287080
Pathway ID Pathway Name
KEGG:05142 Chagas disease (American trypanosomiasis)
KEGG:04062 Chemokine signaling pathway
KEGG:04060 Cytokine-cytokine receptor interaction
KEGG:04623 Cytosolic DNA-sensing pathway
KEGG:05120 Epithelial cell signaling in Helicobacter pylori infection
KEGG:04621 NOD-like receptor signaling pathway
KEGG:05020 Prion diseases
KEGG:05323 Rheumatoid arthritis
REACT:14797 Signaling by GPCR
KEGG:04620 Toll-like receptor signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA35564
    • Releated gene ID Related gene Name
    PA28451DARC
    Releated disease ID Related disease Name
    PA443425Arteriosclerosis
    Releated drug ID Related drug Name
    PA452347glucocorticoids
    PA450541mometasone
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB02322 - Heparin Disaccharide I-S
    DB02353 - Heparin Disaccharide Iii-S
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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