AutismKB 2.0

Annotation Detail for BID


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Basic Information Top
Gene Symbol:BID ( FP497,MGC15319,MGC42355 )
Gene Full Name: BH3 interacting domain death agonist
Band: 22q11.21
Quick LinksEntrez ID:637; OMIM: 601997; Uniprot ID:BID_HUMAN; ENSEMBL ID: ENSG00000015475; HGNC ID: 1050
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04650Natural killer cell mediated cytotoxicity
hsa05416Viral myocarditis
hsa05014Amyotrophic lateral sclerosis (ALS)
hsa05010Alzheimer's disease
hsa04115p53 signaling pathway
hsa04210Apoptosis
hsa05200Pathways in cancer
Pathway IDPathway Name
Apoptosis
Pathway IDPathway Name
200133HIV-1 Nef: Negative effector of Fas and TNF-alpha
200067FAS (CD95) signaling pathway
200148Caspase cascade in apoptosis
200101Direct p53 effectors
200100Ceramide signaling pathway
Pathway IDPathway Name
P00020FAS signaling pathway
P00006Apoptosis signaling pathway
Pathway IDPathway Name
500890BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
500261Activation of BAD and translocation to mitochondria
500258Intrinsic Pathway for Apoptosis
501012Activation, translocation and oligomerization of BAX
500259Activation, myristolyation of BID and translocation to mitochondria
501018Activation and oligomerization of BAK protein
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C067372 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline results in increased expression of BID mRNAincreases expression 15447660
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of BID mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in increased expression of BID mRNAincreases expression 20406850
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of BID mRNAaffects expression 21346803
C005926 2-amino-4-hydroxy-6-formylpteridine 2-amino-4-hydroxy-6-formylpteridine results in decreased expression of BID proteindecreases expression 16019850
C500344 2-methoxyestradiol-3,17-bis-O,O-sulfamate 2-methoxyestradiol-3,17-bis-O,O-sulfamate results in increased cleavage of BID proteinincreases cleavage 15258464
C504711 3,4-dideoxyglucosone-3-ene 3,4-dideoxyglucosone-3-ene results in increased cleavage of BID proteinincreases cleavage 16046310
C090937 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole results in increased cleavage of and results in decreased expression of BID proteindecreases expression|increases cleavage 19481069
C090937 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole [Camptothecin co-treated with 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole] results in increased cleavage of and results in decreased expression of BID proteinaffects cotreatment|decreases expression|increases cleavage 19481069
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of BID mRNAincreases expression 18648102
C110962 5,6-dichlorobenzimidazole 5,6-dichlorobenzimidazole promotes the reaction [TNFSF10 protein results in increased cleavage of BID protein]increases cleavage|increases reaction 15688023
D000082 Acetaminophen Acetaminophen results in increased cleavage of BID proteinincreases cleavage 15345658
D000171 Acrolein Acrolein affects the localization of BID proteinaffects localization 17320762
D000171 Acrolein Acrolein results in increased cleavage of BID proteinincreases cleavage 17320762
D000643 Ammonium Chloride Ammonium Chloride affects the expression of BID mRNAaffects expression 16483693
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one promotes the reaction [arsenic trioxide results in increased cleavage of BID protein]increases cleavage|increases reaction 16972261
D001151 Arsenic Arsenic results in increased expression of BID mRNAincreases expression 19945496
C006632 arsenic trioxide anthra(1,9-cd)pyrazol-6(2H)-one promotes the reaction [arsenic trioxide results in increased cleavage of BID protein]increases cleavage|increases reaction 16972261
C006632 arsenic trioxide arsenic trioxide results in increased cleavage of and results in increased activity of BID proteinincreases activity|increases cleavage 15665116
18546268
C006632 arsenic trioxide arsenic trioxide results in increased cleavage of BID proteinincreases cleavage 19364129
C006632 arsenic trioxide Genistein promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of BID protein]increases activity|increases cleavage|increases reaction 18546268
C006632 arsenic trioxide U 0126 promotes the reaction [arsenic trioxide results in increased cleavage of BID protein]increases cleavage|increases reaction 16972261
C017228 benzo(a)pyrene 7,8-dihydrodiol benzo(a)pyrene 7,8-dihydrodiol results in decreased expression of BID proteindecreases expression 15698582
C072019 benzo(a)pyrene diolepoxide I benzo(a)pyrene diolepoxide I results in decreased expression of BID proteindecreases expression 15698582
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of BID proteindecreases expression 15698582
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of BID proteinincreases expression 16041517
D001564 Benzo(a)pyrene Nitrogen Oxides inhibits the reaction [Benzo(a)pyrene results in increased expression of BID protein]decreases reaction|increases expression 16041517
C427308 benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [silybin results in increased cleavage of BID protein]decreases reaction|increases cleavage 16777994
C005961 bis(tri-n-butyltin)oxide bis(tri-n-butyltin)oxide results in decreased expression of BID mRNAdecreases expression 17553608
C400082 bortezomib [bortezomib co-treated with Butyrates] results in decreased expression of BID proteinaffects cotreatment|decreases expression 12893773
C400082 bortezomib [bortezomib co-treated with vorinostat] results in decreased expression of BID proteinaffects cotreatment|decreases expression 12893773
D002087 Butyrates [bortezomib co-treated with Butyrates] results in decreased expression of BID proteinaffects cotreatment|decreases expression 12893773
D002104 Cadmium Cadmium inhibits the reaction [TNF protein results in increased cleavage of BID protein]decreases reaction|increases cleavage 16263807
D019256 Cadmium Chloride Cadmium Chloride inhibits the reaction [TNF protein results in increased cleavage of BID protein]decreases reaction|increases cleavage 16263807
D002110 Caffeine Caffeine inhibits the reaction [silybin results in increased cleavage of BID protein]decreases reaction|increases cleavage 16777994
D002166 Camptothecin [Camptothecin co-treated with 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole] results in increased cleavage of and results in decreased expression of BID proteinaffects cotreatment|decreases expression|increases cleavage 19481069
D002166 Camptothecin Camptothecin results in increased cleavage of and results in decreased expression of BID proteindecreases expression|increases cleavage 19481069
C111238 carboxycinnamic acid bishydroxamide carboxycinnamic acid bishydroxamide results in increased cleavage of BID proteinincreases cleavage 15897598
C012843 cinnamic aldehyde cinnamic aldehyde results in increased cleavage of BID proteinincreases cleavage 15964311
D003042 Cocaine Cocaine affects the expression of BID mRNAaffects expression 15681117
C463759 codonoposide codonoposide results in increased cleavage of and affects the localization of BID proteinaffects localization|increases cleavage 15863893
D016572 Cyclosporine Cyclosporine results in increased expression of BID mRNAincreases expression 20106945
D004317 Doxorubicin BCL2L1 protein inhibits the reaction [BID protein results in increased susceptibility to Doxorubicin]decreases reaction|increases response to substance 15289866
D004317 Doxorubicin BID protein results in increased susceptibility to Doxorubicinincreases response to substance 15289866
D004317 Doxorubicin Doxorubicin affects the cleavage of BID proteinaffects cleavage 15870702
D004317 Doxorubicin [Doxorubicin co-treated with Phellinus linteus extract] results in increased cleavage of BID proteinaffects cotreatment|increases cleavage 16868541
D004317 Doxorubicin Doxorubicin results in decreased expression of BID mRNAdecreases expression 16705698
D004317 Doxorubicin [Indomethacin results in increased cleavage of BID protein] which results in increased susceptibility to Doxorubicinincreases cleavage|increases response to substance 15812552
C022999 echinocystic acid echinocystic acid analog results in increased cleavage of and affects the localization of BID proteinaffects localization|increases cleavage 15863893
D004958 Estradiol Estradiol inhibits the reaction [Etoposide results in increased expression of BID mRNA]decreases reaction|increases expression 19426747
D004958 Estradiol Estradiol results in decreased expression of BID mRNAdecreases expression 19426747
D004958 Estradiol Estradiol results in increased expression of BID mRNAincreases expression 20106945
C456800 ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate [flavopiridol co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased cleavage of BID proteinaffects cotreatment|increases cleavage 15634644
D005047 Etoposide Estradiol inhibits the reaction [Etoposide results in increased expression of BID mRNA]decreases reaction|increases expression 19426747
D005047 Etoposide Etoposide results in increased expression of BID mRNAincreases expression 19426747
C077990 flavopiridol BCL2 protein mutant form inhibits the reaction [flavopiridol results in increased cleavage of BID protein]decreases reaction|increases cleavage 12170773
C077990 flavopiridol [flavopiridol co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased cleavage of BID proteinaffects cotreatment|increases cleavage 15634644
C077990 flavopiridol flavopiridol results in increased cleavage of BID proteinincreases cleavage 12170773
D005472 Fluorouracil BCL2L1 protein inhibits the reaction [BID protein results in increased susceptibility to Fluorouracil]decreases reaction|increases response to substance 15289866
D005472 Fluorouracil BID protein mutant form results in decreased susceptibility to Fluorouracildecreases response to substance 15095271
D005472 Fluorouracil BID protein results in increased susceptibility to Fluorouracilincreases response to substance 15289866
D005620 Freund's Adjuvant [Urethane co-treated with Freund's Adjuvant] results in increased expression of BID mRNAaffects cotreatment|increases expression 12400877
D005665 Furosemide Furosemide affects the expression of BID mRNAaffects expression 17497460
D005688 Galactosamine [lipopolysaccharide, Escherichia coli 0111 B4 co-treated with Galactosamine] results in increased cleavage of BID proteinaffects cotreatment|increases cleavage 12907702
C054597 garcinol garcinol results in increased cleavage of BID proteinincreases cleavage 16052481
D019833 Genistein Genistein promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of BID protein]increases activity|increases cleavage|increases reaction 18546268
D019833 Genistein Genistein results in increased cleavage of and results in increased activity of BID proteinincreases activity|increases cleavage 18546268
D017313 Fenretinide [Fenretinide co-treated with TNFSF10 protein] results in increased cleavage of BID proteinaffects cotreatment|increases cleavage 17273769
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of BID mRNAincreases expression 14689451
D007213 Indomethacin Indomethacin results in increased cleavage of BID proteinincreases cleavage 15812552
D007213 Indomethacin [Indomethacin results in increased cleavage of BID protein] which results in increased susceptibility to Doxorubicinincreases cleavage|increases response to substance 15812552
D007530 Isoflurane Isoflurane results in decreased expression of BID mRNAdecreases expression 16978161
C440499 lipopolysaccharide, Escherichia coli 0111 B4 [lipopolysaccharide, Escherichia coli 0111 B4 co-treated with Galactosamine] results in increased cleavage of BID proteinaffects cotreatment|increases cleavage 12907702
D015735 Mifepristone Mifepristone results in increased expression of BID mRNAincreases expression 17584828
D008911 Minocycline [Minocycline results in increased expression of BCL2 protein] which binds to BID proteinaffects binding|increases expression 15004018
C406082 monomethylarsonous acid monomethylarsonous acid results in increased expression of BID mRNAincreases expression 19945496
D009151 Mustard Gas Mustard Gas results in increased expression of BID mRNAincreases expression 18955075
C029938 nickel sulfate nickel sulfate results in increased expression of BID mRNAincreases expression 16780908
D009569 Nitric Oxide Nitric Oxide results in increased cleavage of BID proteinincreases cleavage 15126337
D009589 Nitrogen Oxides Nitrogen Oxides inhibits the reaction [Benzo(a)pyrene results in increased expression of BID protein]decreases reaction|increases expression 16041517
D009637 Nordihydroguaiaretic Acid [Nordihydroguaiaretic Acid co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of BID proteinaffects cotreatment|increases activity|increases cleavage 17645780
D017239 Paclitaxel Paclitaxel results in increased expression of BID proteinincreases expression 14749477
C482884 panduratin A panduratin A results in decreased expression of BID proteindecreases expression 16497706
C002669 parthenolide parthenolide results in increased cleavage of BID proteinincreases cleavage 16024633
C526145 Phellinus linteus extract [Doxorubicin co-treated with Phellinus linteus extract] results in increased cleavage of BID proteinaffects cotreatment|increases cleavage 16868541
C058305 phenethyl isothiocyanate phenethyl isothiocyanate results in increased expression of and results in increased cleavage of BID proteinincreases cleavage|increases expression 16054126
C471183 phenoxodiol phenoxodiol results in increased activity of BID proteinincreases activity 16388521
C121565 pifithrin pifithrin inhibits the reaction [silybin results in increased cleavage of BID protein]decreases reaction|increases cleavage 16777994
C006253 pirinixic acid pirinixic acid results in decreased expression of BID mRNAdecreases expression 18445702
D010936 Plant Extracts Plant Extracts results in increased cleavage of BID proteinincreases cleavage 17619071
D011374 Progesterone Progesterone results in decreased expression of BID mRNAdecreases expression 18037150
C031280 pyrazole pyrazole results in increased expression of BID mRNAincreases expression 17945193
D011794 Quercetin Quercetin promotes the reaction [TNFSF10 protein results in increased cleavage of BID protein]increases cleavage|increases reaction 17876056
C059514 resveratrol resveratrol results in increased cleavage of BID proteinincreases cleavage 16617056
C059514 resveratrol resveratrol results in increased expression of BID proteinincreases expression 16731767
D012643 Selenium Selenium results in increased cleavage of BID proteinincreases cleavage 12432279
C440975 silybin benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [silybin results in increased cleavage of BID protein]decreases reaction|increases cleavage 16777994
C440975 silybin Caffeine inhibits the reaction [silybin results in increased cleavage of BID protein]decreases reaction|increases cleavage 16777994
C440975 silybin pifithrin inhibits the reaction [silybin results in increased cleavage of BID protein]decreases reaction|increases cleavage 16777994
C440975 silybin silybin affects the localization of BID protein modified formaffects localization 16777994
C440975 silybin silybin results in increased cleavage of BID proteinincreases cleavage 16777994
C061636 suillin suillin results in decreased expression of BID proteindecreases expression 19616521
C025462 sulindac sulfide sulindac sulfide results in increased cleavage of BID proteinincreases cleavage 12203115
C025462 sulindac sulfide sulindac sulfide results in decreased expression of BID proteindecreases expression 16886631
D013654 Taurine Taurine results in decreased expression of BID mRNAdecreases expression 16579726
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased cleavage of BID proteinincreases cleavage 15972635
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of BID mRNAincreases expression 15972635
14718646
D019772 Topotecan BID protein affects the susceptibility to Topotecanaffects response to substance 16217747
C496197 trans-10,cis-12-conjugated linoleic acid trans-10,cis-12-conjugated linoleic acid results in increased cleavage of BID proteinincreases cleavage 16005259
D014212 Tretinoin Tretinoin results in decreased expression of BID proteindecreases expression 16242776
D014222 Triamcinolone Acetonide Triamcinolone Acetonide results in increased expression of BID proteinincreases expression 15987869
C113580 U 0126 U 0126 promotes the reaction [arsenic trioxide results in increased cleavage of BID protein]increases cleavage|increases reaction 16972261
D014520 Urethane [Urethane co-treated with Freund's Adjuvant] results in increased expression of BID mRNAaffects cotreatment|increases expression 12400877
C111237 vorinostat [bortezomib co-treated with vorinostat] results in decreased expression of BID proteinaffects cotreatment|decreases expression 12893773
C111237 vorinostat TNFSF10 protein promotes the reaction [vorinostat results in increased cleavage of BID protein]increases cleavage|increases reaction 17410615
C111237 vorinostat vorinostat results in increased cleavage of BID proteinincreases cleavage 17410615
15897598
C088658 zoledronic acid zoledronic acid results in increased expression of BID mRNAincreases expression 19036117
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.1011752688 14514962 15322242
MESH:D000138 Acidosis Ammonium Chloride 2.7918287403
MESH:D000168 Acrocephalosyndactylia U 0126 4.7217694057
MESH:D058186 Acute Kidney Injury pifithrin 10.6817670903
MESH:D058186 Acute Kidney Injury resveratrol 10.6816538975
MESH:D058186 Acute Kidney Injury zoledronic acid 10.6819715164
MESH:D055371 Acute Lung Injury Acrolein 11.2721297076 20525806
MESH:D055371 Acute Lung Injury nickel sulfate 11.2716100012 19131640 12718980 11954676
MESH:D055371 Acute Lung Injury pirinixic acid 11.2718653653
MESH:D000210 Acute-Phase Reaction zoledronic acid 4.7020200999
MESH:D000230 Adenocarcinoma arsenic trioxide 23.1411798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 23.1420464547 20127859
MESH:D000230 Adenocarcinoma Doxorubicin 23.1417418594
MESH:D000230 Adenocarcinoma Estradiol 23.1411473722
MESH:D000230 Adenocarcinoma Fenretinide 23.1410697514
MESH:D000230 Adenocarcinoma Fluorouracil 23.1417638652
MESH:D000230 Adenocarcinoma Genistein 23.1411473722
MESH:D000230 Adenocarcinoma Indomethacin 23.1416537180
MESH:D000230 Adenocarcinoma Urethane 23.1418316556
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Urethane 4.9215814487
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 15.653712494
MESH:D000236 Adenoma Benzo(a)pyrene 15.656695378
MESH:D000236 Adenoma Indomethacin 15.6511497255
MESH:D000236 Adenoma resveratrol 15.6515688382
MESH:D000236 Adenoma Urethane 15.6510530776 16926031 11497255 6695378 17195641 10822126 17093202
MESH:D018248 Adenoma, Liver Cell pirinixic acid 7.3416434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 7.3416835633
MESH:D018246 Adrenocortical Adenoma Arsenic 4.4217306315
MESH:D000419 Albuminuria Doxorubicin 3.8021441931
MESH:D000505 Alopecia Tretinoin 2.9815955085
MESH:D016301 Alveolar Bone Loss Indomethacin 4.5817225004
MESH:D000544 Alzheimer Disease Acrolein 12.4817570602 15207723 14715435
MESH:D000544 Alzheimer Disease Indomethacin 12.4815579461 17627676
MESH:D000544 Alzheimer Disease Nitric Oxide 12.4817556102
MESH:D000544 Alzheimer Disease Plant Extracts 12.4816962711
MESH:D000544 Alzheimer Disease resveratrol 12.4816162502 16183991
MESH:D000544 Alzheimer Disease sulindac sulfide 12.4818759972
MESH:D000740 Anemia Fluorouracil 6.4115504547 16511603 17963324
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.4111748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.5417084956
MESH:D000799 Angioedema Acetaminophen 3.0510982225
MESH:D001014 Aortic Aneurysm Indomethacin 4.1110231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 9.1919183758
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 9.1910388637
MESH:D020261 Arsenic Poisoning Arsenic 2.5912569548 16835338 18414634 16251483
MESH:D001161 Arteriosclerosis Acrolein 4.2515014928
MESH:D018771 Arthralgia Indomethacin 4.382160914
MESH:D001169 Arthritis, Experimental Plant Extracts 9.3514686799
MESH:D001169 Arthritis, Experimental resveratrol 9.3517115116
MESH:D001169 Arthritis, Experimental Tretinoin 9.3516412693
MESH:D001172 Arthritis, Rheumatoid Indomethacin 6.1311248219
MESH:D001172 Arthritis, Rheumatoid Minocycline 6.1314528503
MESH:D001172 Arthritis, Rheumatoid Tretinoin 6.1316292516
MESH:D001249 Asthma Mustard Gas 3.9210378619
MESH:D001249 Asthma Tretinoin 3.9216456186
MESH:D001260 Ataxia Telangiectasia Quercetin 4.2015336622
MESH:D050197 Atherosclerosis Acrolein 11.4917363696 16126721 16037261
MESH:D050197 Atherosclerosis Arsenic 11.4912928151 19371607
MESH:D050197 Atherosclerosis Cadmium 11.4915687053
MESH:D050197 Atherosclerosis resveratrol 11.4917967414 16873680
MESH:D001321 Autistic Disorder Acetaminophen 1.5618445737
MESH:D001327 Autoimmune Diseases Quercetin 3.6519761891
MESH:D001471 Barrett Esophagus Tretinoin 3.6616935849
MESH:D001477 Bartter Syndrome Indomethacin 4.2210684365
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.231440618 11289319
MESH:D001768 Blister Mustard Gas 4.3819167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 16.2116206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 16.2119483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 16.2112125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 16.2116206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.0015340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.2215746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 9.5414601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 9.5414601052
MESH:D001859 Bone Neoplasms Paclitaxel 8.4415867366
MESH:D001859 Bone Neoplasms zoledronic acid 8.4417312309 11697798 15867366 16121404 16778634 19442620
MESH:D001862 Bone Resorption Freund's Adjuvant 7.9316769263
MESH:D001862 Bone Resorption zoledronic acid 7.9316769263 18496637 18404659 8053405 11869084 15845617
MESH:D001929 Brain Edema Indomethacin 4.2311481608
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.5417868700
MESH:D001930 Brain Injuries Progesterone 3.5015845082 15380490 15665606
MESH:D002545 Brain Ischemia Indomethacin 12.7012524144
MESH:D002545 Brain Ischemia Plant Extracts 12.7016041641
MESH:D002545 Brain Ischemia resveratrol 12.7017600658
MESH:D001932 Brain Neoplasms Doxorubicin 6.8517150277
MESH:D001932 Brain Neoplasms Fenretinide 6.8516187019
MESH:D001943 Breast Neoplasms 2-methoxyestradiol-3,17-bis-O,O-sulfamate 21.6917957467 15862969 17426705 14970876 12711022 12711013
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 21.6920146248 17474063
MESH:D001943 Breast Neoplasms Doxorubicin 21.6918695136 17983394 16595493 16096432 19526202 17369602 15136595 16115903 16264153 18628466 15634643 11325840 17426702 15692762 15567936 15668708 16322301 15993339 15939500 18234424 16826403 16935488 15994142 18382427
MESH:D001943 Breast Neoplasms Estradiol 21.6912948864 16675129 17289903 17261762 17018787 14630087 19861407 18497071
MESH:D001943 Breast Neoplasms Etoposide 21.6916322251
MESH:D001943 Breast Neoplasms Fenretinide 21.6916601279
MESH:D001943 Breast Neoplasms flavopiridol 21.6912517783
MESH:D001943 Breast Neoplasms Fluorouracil 21.6916110121 15136595 16557594 19217205 18357371 16595493 18608205
MESH:D001943 Breast Neoplasms Genistein 21.6917200150 16541309 16873071
MESH:D001943 Breast Neoplasms Indomethacin 21.6917401462
MESH:D001943 Breast Neoplasms Nitric Oxide 21.6915631943
MESH:D001943 Breast Neoplasms Nordihydroguaiaretic Acid 21.6918418215
MESH:D001943 Breast Neoplasms Paclitaxel 21.6918223236 16244791 18234424 16273361 16115903 18323546 11325840 15136595
MESH:D001943 Breast Neoplasms parthenolide 21.6916873071
MESH:D001943 Breast Neoplasms Progesterone 21.6917614352 16175315 15562024
MESH:D001943 Breast Neoplasms Quercetin 21.6918628248
MESH:D001943 Breast Neoplasms resveratrol 21.6917534123 16393696 17651959
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 21.6920435547
MESH:D001943 Breast Neoplasms Tretinoin 21.6916166294 16443354 16873071
MESH:D001943 Breast Neoplasms vorinostat 21.6916144943
MESH:D001943 Breast Neoplasms zoledronic acid 21.6916096432 18695136
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.3815286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.1917687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.8116813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.6011589617
MESH:D002056 Burns Indomethacin 3.9510459503
MESH:D002057 Burns, Chemical Plant Extracts 4.549625245
MESH:D002100 Cachexia Indomethacin 4.2315625704 16537180 15141370 11239499
MESH:D002105 Cadmium Poisoning Quercetin 4.7516962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.6916111702
MESH:D002276 Carcinoid Tumor Doxorubicin 9.7316051944
MESH:D002276 Carcinoid Tumor Fluorouracil 9.7316051944
MESH:D002277 Carcinoma Fluorouracil 6.0717121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.0716835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.0915504454 17687452
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.3716168501
MESH:D006528 Carcinoma, Hepatocellular marker/mechanism 15289866
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 42.8016705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 42.8016705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 42.803581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 42.803084413
MESH:D006528 Carcinoma, Hepatocellular anthra(1,9-cd)pyrazol-6(2H)-one 42.8019418558
MESH:D006528 Carcinoma, Hepatocellular Arsenic 42.8016507464 17306315
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 42.8014691202 15553829 11135700 15073043 16217749
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 42.8016234567 17876044 16023760 18059187
MESH:D006528 Carcinoma, Hepatocellular Estradiol 42.8016924424
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 42.8016270382 17159502
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 42.8018930000 17088986 16799960 17971768 16332177 17045692
MESH:D006528 Carcinoma, Hepatocellular Genistein 42.8016924424
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 42.8016391822
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 42.8016313753
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 42.8018834353
MESH:D006528 Carcinoma, Hepatocellular Quercetin 42.8012508355 19519916
MESH:D006528 Carcinoma, Hepatocellular resveratrol 42.8016227395 19321006
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 42.801917145
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 8.8511053908
MESH:D018827 Carcinoma, Lewis Lung resveratrol 8.8516675471
MESH:D018276 Carcinoma, Medullary Indomethacin 4.5714736730 18791128 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung bortezomib 7.2716052434
MESH:D002289 Carcinoma, Non-Small-Cell Lung sulindac sulfide 7.2712391285
MESH:D002289 Carcinoma, Non-Small-Cell Lung zoledronic acid 7.2719233551
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.1917234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.0819014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 15.577296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 15.5716201981 1485588
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 15.5718695887
MESH:D002292 Carcinoma, Renal Cell Indomethacin 15.5717341418
MESH:D002292 Carcinoma, Renal Cell zoledronic acid 15.5718507039
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.4312490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 20.5418922899 15504454 17687452
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 20.5420419170
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 20.546189445
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 20.5416274795
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 20.5417066447 18986760 16757204 16280240
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 20.5415482327 12636206
MESH:D002294 Carcinoma, Squamous Cell resveratrol 20.5416227395
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 20.5416096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Arsenic 3.3918640142
MESH:D006332 Cardiomegaly Plant Extracts 8.6417645561
MESH:D006332 Cardiomegaly Quercetin 8.6419794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 8.6418670907 18850075 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 2.9816364871 16242529 17329180 16612575 17131338 17382496 18627295 17308081 16651473 17519947 17351982 17924179 16109756 17007740 15811867 16455267 15505089 15476868 16269455 16952015 17928571 16731534 15792986 17974986 16278810
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.6116243910 17334414
MESH:D002318 Cardiovascular Diseases Arsenic 12.6319152805 15738583 17938729
MESH:D002318 Cardiovascular Diseases Genistein 12.6316332659
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 12.6316936243
MESH:D002318 Cardiovascular Diseases resveratrol 12.6315458977
MESH:D002340 Carotid Artery Diseases Arsenic 3.6416973168 18022660
MESH:D002386 Cataract Acetaminophen 5.5110977129
MESH:D002386 Cataract Tretinoin 5.5117460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 27.316135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 27.317505956
MESH:D002471 Cell Transformation, Neoplastic Cadmium 27.3117332340
MESH:D002471 Cell Transformation, Neoplastic cinnamic aldehyde 27.318243401
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 27.3112371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 27.3118566989
MESH:D002471 Cell Transformation, Neoplastic Galactosamine 27.317505956
MESH:D002471 Cell Transformation, Neoplastic monomethylarsonous acid 27.3119716837
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 10.4016154183
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 10.4016129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.4916835633
MESH:D002764 Cholecystitis Indomethacin 4.3811181007
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 14.3219486331 9022650
MESH:D002779 Cholestasis Cyclosporine 14.3219486331
MESH:D002779 Cholestasis Nitric Oxide 14.3216919318
MESH:D002779 Cholestasis pirinixic acid 14.3219176532
MESH:D002822 Choriocarcinoma Tretinoin 4.3716461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 7.5715340226 8697196 16354765 15668235 12621046
MESH:D002972 Cleft Palate Tretinoin 7.579407595
MESH:D002972 Cleft Palate Urethane 7.5712810352
MESH:D019970 Cocaine-Related Disorders Cocaine 4.9419606084
MESH:D003092 Colitis resveratrol 11.6916474422
MESH:D003092 Colitis Selenium 11.6917936198
MESH:D003092 Colitis Tretinoin 11.6917035595
MESH:D003093 Colitis, Ulcerative phenethyl isothiocyanate 3.3220423518
MESH:D003110 Colonic Neoplasms Butyrates 16.5915936596
MESH:D003110 Colonic Neoplasms cinnamic aldehyde 16.5917510524 16343908
MESH:D003110 Colonic Neoplasms Fluorouracil 16.5917725105 17287894 16510598 17169374 18772588 17018589 15001691 17016597 17172411 16340194
MESH:D003110 Colonic Neoplasms Genistein 16.5917182828
MESH:D003110 Colonic Neoplasms Indomethacin 16.5915625704 15786552 11260862 15936596 15637740 15963497
MESH:D003110 Colonic Neoplasms Nordihydroguaiaretic Acid 16.5915936596
MESH:D003110 Colonic Neoplasms Quercetin 16.5917148506 17191121 19440933 19056647 11134977 16640504 15741050
MESH:D003110 Colonic Neoplasms resveratrol 16.5916338953
MESH:D015179 Colorectal Neoplasms Acrolein 12.5117597105
MESH:D015179 Colorectal Neoplasms arsenic trioxide 12.5120501625
MESH:D015179 Colorectal Neoplasms Doxorubicin 12.5118259882 18802399
MESH:D015179 Colorectal Neoplasms Fenretinide 12.5117273769
MESH:D015179 Colorectal Neoplasms Fluorouracil 12.5116524972 17255274 20501625 14970324 18802399 18448328 16391804 17094418 17695437 18509181 18383874 15148649 17401013 16331619 18288408 18949393 17594712 17016601 16282729 17454858 15289873 16303861
MESH:D015179 Colorectal Neoplasms Indomethacin 12.5112606626 18059344 17054584 11197048
MESH:D015179 Colorectal Neoplasms Paclitaxel 12.5118802399
MESH:D015179 Colorectal Neoplasms Quercetin 12.5118852136 18095365
MESH:D015179 Colorectal Neoplasms resveratrol 12.5116550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.3914669216 17141729
MESH:D003327 Coronary Disease resveratrol 3.2116507316
MESH:D023903 Coronary Restenosis arsenic trioxide 3.4412609071
MESH:D018352 Coronavirus Infections Indomethacin 4.9217302372
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.0310525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.0315322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.039211117 14991402 16925845 9664655 9142499 9125849 9224671 17551590 8800419 10589399
MESH:D003490 Cyanosis 2,4-dinitrotoluene 8.3818551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 8.3818551238
MESH:D003556 Cystitis Acrolein 4.6012161096
MESH:D007644 Darier Disease Fluorouracil 4.0116733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.3715213294
MESH:D015140 Dementia, Vascular Nitric Oxide 5.1817556102
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 7.578970840 12868966 11298694 18759878 14531868 2524372 11906362 8156756
MESH:D017449 Dermatitis, Allergic Contact cinnamic aldehyde 7.5711042091
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 7.5716823706 11298694 16780908
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.0018249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 2.782952479 3621924
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 6.4019496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 6.4016873680
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 3.4416647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.4417107852
MESH:D058065 Diabetic Cardiomyopathies Taurine 5.2716025228
MESH:D003928 Diabetic Nephropathies Estradiol 11.2919279558
MESH:D003928 Diabetic Nephropathies Plant Extracts 11.2919706694
MESH:D003928 Diabetic Nephropathies resveratrol 11.2916286809
MESH:D003929 Diabetic Neuropathies Progesterone 3.7317187935
MESH:D003967 Diarrhea Indomethacin 6.157237001 7907874
MESH:D003967 Diarrhea vorinostat 6.1520479100
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 22.6321346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 22.6318551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 22.636679447 9022650 16192314 9328219 18692083 8291058 11289319 1440618 9653073 7440962 6482804 18289764 18648102
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 22.6318071297 19164858 11461765 16485898 11834606 10774834 16227642 18713872 17906064 12392966 11287661 16393943 14986274 19420014 12705907 19370779 12958197 11743745 10915739 16081117 17522070 15619225 11421492 16109766 19739265 16177239 12153990 2444490 19416960 11739529 14550746 15968718 16781746 19085960 10663392 19923254 11529661 17562736 14725611 12594235 12540782
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 22.6317416283
MESH:D056486 Drug-Induced Liver Injury Galactosamine 22.6315968718
MESH:D056486 Drug-Induced Liver Injury pyrazole 22.6312499123
MESH:D056486 Drug-Induced Liver Injury Selenium 22.6315131321
MESH:D056486 Drug-Induced Liver Injury Taurine 22.639328219
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 22.6320420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.3119426721
MESH:D004362 Drug Toxicity Doxorubicin 6.0918602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.0911462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.3716133044 17190690 16326151 12774134 18043480 18446180
MESH:D004381 Duodenal Ulcer Indomethacin 3.4111991626 11595431 10671773 17045617 11595415 17202747 17351913 17329845 16699067 11535926 17151854
MESH:D004417 Dyspnea Furosemide 4.1616935035
MESH:D004487 Edema Furosemide 22.0611834646
MESH:D004487 Edema Indomethacin 22.0616100529 7990266 7907874 8273558 19703484 8985016 10653021
MESH:D004487 Edema Mustard Gas 22.069260866 11428647 11402378 11428631
MESH:D004487 Edema pirinixic acid 22.0612083418
MESH:D004487 Edema Plant Extracts 22.0612787963
MESH:D004487 Edema resveratrol 22.068985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 22.0612711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 9.3215322242 16714409 18230668
MESH:D004489 Edema, Cardiac Tretinoin 9.3218230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Minocycline 11.4611835378
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 11.4617692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 11.4617872969
MESH:D004714 Endometrial Hyperplasia Genistein 3.8116402032
MESH:D016889 Endometrial Neoplasms Doxorubicin 13.2417359293
MESH:D016889 Endometrial Neoplasms Estradiol 13.2418566989 19148513 11473722
MESH:D016889 Endometrial Neoplasms Genistein 13.2411473722
MESH:D016889 Endometrial Neoplasms Tretinoin 13.2416569247
MESH:D004715 Endometriosis Indomethacin 16.2615652904
MESH:D004715 Endometriosis Mifepristone 16.2616134523
MESH:D004715 Endometriosis Progesterone 16.2616134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 16.269294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 11.4318037988
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 11.4315268973
MESH:D019446 Endotoxemia Indomethacin 8.5218509659
MESH:D019446 Endotoxemia lipopolysaccharide, Escherichia coli 0111 B4 8.5212954792
MESH:D004751 Enteritis Indomethacin 3.9616328016 17763956 10567023
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 9.8517980183
MESH:D020345 Enterocolitis, Necrotizing resveratrol 9.8517923197
MESH:D004802 Eosinophilia Indomethacin 3.3111298111
MESH:D004827 Epilepsy Plant Extracts 3.2719439326 19700373
MESH:D004890 Erythema Mustard Gas 4.389357497
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 13.733581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 13.7312903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 13.7316530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 13.7315173087 17638652 16481741 16785472 16337965
MESH:D004938 Esophageal Neoplasms Indomethacin 13.7311005569
MESH:D004938 Esophageal Neoplasms Paclitaxel 13.7316481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 6.8011564622
MESH:D005124 Eye Abnormalities Tretinoin 6.809664655 16938888
MESH:D005221 Fatigue vorinostat 4.8220479100
MESH:D005234 Fatty Liver arsenic trioxide 13.1015073043
MESH:D005234 Fatty Liver Cyclosporine 13.1019224547
MESH:D005234 Fatty Liver pirinixic acid 13.1020131406 19236843
MESH:D005234 Fatty Liver Plant Extracts 13.1015975614
MESH:D005264 Femoral Fractures zoledronic acid 5.0516234978
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.7011858732
MESH:D005334 Fever Indomethacin 7.5210431976 17627676 11852909
MESH:D005334 Fever lipopolysaccharide, Escherichia coli 0111 B4 7.5216997862
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.236705139
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 3.8119069698
MESH:D005354 Fibrosarcoma Indomethacin 4.1210962813
MESH:D005355 Fibrosis Cyclosporine 19.8112168785 12639820
MESH:D005355 Fibrosis Indomethacin 19.8117994277
MESH:D005355 Fibrosis Quercetin 19.8119474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 19.8120067830
MESH:D005355 Fibrosis Tretinoin 19.8117994277
MESH:D005499 Folliculitis Indomethacin 4.3811298111
MESH:D005534 Foot Diseases Arsenic 4.776392382
MESH:D005600 Fragile X Syndrome Minocycline 5.9718835858
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.5216904648
MESH:D005756 Gastritis Acetaminophen 8.5316983495
MESH:D005756 Gastritis Indomethacin 8.5315046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.448708960
MESH:D005909 Glioblastoma Doxorubicin 20.6217150277
MESH:D005909 Glioblastoma Fenretinide 20.6216187019
MESH:D005909 Glioblastoma Genistein 20.6216598420
MESH:D005909 Glioblastoma Indomethacin 20.6212870263
MESH:D005909 Glioblastoma Quercetin 20.6219804834
MESH:D005909 Glioblastoma Tretinoin 20.6217312396
MESH:D005910 Glioma Fluorouracil 7.7416145905
MESH:D005910 Glioma Indomethacin 7.7418371953 16487511
MESH:D005910 Glioma Quercetin 7.7417643826
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.6411849393
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.317505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.8010696789
MESH:D006073 Gout Indomethacin 4.5711248219
MESH:D006261 Headache Nitric Oxide 4.3911554966 11284996
MESH:D006258 Head and Neck Neoplasms Doxorubicin 13.8215692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 13.8218337622 15102660 15162350
MESH:D006258 Head and Neck Neoplasms Indomethacin 13.8215482327
MESH:D006258 Head and Neck Neoplasms Tretinoin 13.8216096774
MESH:D034381 Hearing Loss Furosemide 4.1617868369
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.3716084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 8.3220471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 8.3211294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 8.329664655 14991402
MESH:D006331 Heart Diseases Doxorubicin 9.6816879835 16707910 14766674 16330681 16244372 12587719 16495754 16144979 17875725 16244371 18006777 18674790 17888722
MESH:D006331 Heart Diseases pifithrin 9.6814766674
MESH:D006331 Heart Diseases Urethane 9.6816046796
MESH:D006333 Heart Failure Doxorubicin 16.5717481944
MESH:D006333 Heart Failure Furosemide 16.5716011733 12660669 16845234
MESH:D006333 Heart Failure pirinixic acid 16.5720558911
MESH:D006333 Heart Failure Plant Extracts 16.5718097624
MESH:D006333 Heart Failure Selenium 16.5717162251
MESH:D006394 Hemangiosarcoma Doxorubicin 3.2015692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.6415720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.6311000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 3.8615633222
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 7.296705139
MESH:D006505 Hepatitis Caffeine 7.2911394713
MESH:D019698 Hepatitis C, Chronic Indomethacin 3.9415135802
MESH:D006521 Hepatitis, Chronic Minocycline 5.3614986274
MESH:D006529 Hepatomegaly pirinixic acid 5.7719176532 18467677 19772884 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 5.7712621046 16120746 15340226
MESH:D006558 Herpes Genitalis Estradiol 4.2415709030
MESH:D006561 Herpes Simplex Etoposide 12.1110809021
MESH:D006561 Herpes Simplex Plant Extracts 12.1110715843
MESH:D006561 Herpes Simplex resveratrol 12.1116876885
MESH:D015658 HIV Infections Plant Extracts 3.2212878215
MESH:D006689 Hodgkin Disease Doxorubicin 5.5615147373 18501091 17606976
MESH:D006689 Hodgkin Disease Etoposide 5.5616200630 17606976 18180244 15147373 16135485
MESH:D019584 Hot Flashes Estradiol 7.7217088409
MESH:D019584 Hot Flashes Plant Extracts 7.7216566672 14716179 17454163
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.258697196 18606429 16959395 15340226 16354765
MESH:D006930 Hyperalgesia Acetaminophen 17.8416870215
MESH:D006930 Hyperalgesia Freund's Adjuvant 17.8416769263
MESH:D006930 Hyperalgesia Indomethacin 17.8412727271
MESH:D006930 Hyperalgesia Tretinoin 17.8416870215
MESH:D006930 Hyperalgesia zoledronic acid 17.8416769263
MESH:D034321 Hyperamylasemia Indomethacin 4.9217883296
MESH:D006934 Hypercalcemia bortezomib 14.3118089816
MESH:D006934 Hypercalcemia Furosemide 14.3117652376
MESH:D006934 Hypercalcemia zoledronic acid 14.3119622757 18089816
MESH:D053565 Hypercalciuria Furosemide 4.8717652376
MESH:D006937 Hypercholesterolemia resveratrol 3.3117188708
MESH:D006940 Hyperemia Indomethacin 10.1412524144
MESH:D006940 Hyperemia Nitric Oxide 10.1411156591
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.8116778211
MESH:D006943 Hyperglycemia pirinixic acid 6.9620558911
MESH:D006943 Hyperglycemia Quercetin 6.9618262572 11834736
MESH:D020138 Hyperhomocysteinemia Plant Extracts 3.8016484555
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 3.7717050553
MESH:D006949 Hyperlipidemias Indomethacin 11.4817546600
MESH:D006949 Hyperlipidemias Plant Extracts 11.4815268973 15975614
MESH:D006949 Hyperlipidemias resveratrol 11.4816873680
MESH:D006962 Hyperparathyroidism, Secondary Furosemide 5.0815086907
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.1815034207
MESH:D006973 Hypertension Arsenic 9.279931084 11953799 16076760
MESH:D006973 Hypertension Cyclosporine 9.2710903974
MESH:D006973 Hypertension Quercetin 9.2718356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 9.2718850075 18670907
MESH:D046110 Hypertension, Pregnancy-Induced Furosemide 4.5316612254
MESH:D006976 Hypertension, Pulmonary Nitric Oxide 3.8315838368
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.6117488730
MESH:D006987 Hypesthesia Arsenic 4.7716093927
MESH:D006996 Hypocalcemia zoledronic acid 5.4012669777
MESH:C537153 Hypomagnesemia primary Furosemide 4.8711041285
MESH:D007019 Hypoproteinemia Furosemide 5.0816096441
MESH:D007022 Hypotension Furosemide 7.4811041285
MESH:D007022 Hypotension Isoflurane 7.4812967683
MESH:D007024 Hypotension, Orthostatic Furosemide 4.6315811171
MESH:D007077 Ileal Diseases Indomethacin 4.2310574470 18306037
MESH:D007079 Ileitis Indomethacin 4.5710647630 16133968 10651667
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.5816133044
MESH:D020244 Infarction, Middle Cerebral Artery pifithrin 15.1619475672
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 15.1615869954
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 15.1617600658
MESH:D007249 Inflammation Freund's Adjuvant 17.0416793879
MESH:D007249 Inflammation Indomethacin 17.043291741 7812673 12568917
MESH:D007249 Inflammation Mustard Gas 17.049357497 11428631 11428620 11428647 9260866 16001271 8975870 11402378 17524151
MESH:D007249 Inflammation Plant Extracts 17.0419332304 12787963 16366677 15997105
MESH:D007249 Inflammation Progesterone 17.0415869954
MESH:D007249 Inflammation resveratrol 17.0416366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 17.0412200463 12878042
MESH:D007251 Influenza, Human Nordihydroguaiaretic Acid 20.2718473937
MESH:D007251 Influenza, Human Quercetin 20.2716624496
MESH:D007251 Influenza, Human resveratrol 20.2716624496
MESH:D007251 Influenza, Human Selenium 20.2716624496
MESH:D007333 Insulin Resistance Estradiol 5.3516393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 5.3516306350
MESH:D007410 Intestinal Diseases Indomethacin 12.2218236018 15831440 11713966 17329856 17994277 11686837 15610444 11855677 10210152
MESH:D007410 Intestinal Diseases Nitric Oxide 12.2211574821 10210152 11713966
MESH:D007410 Intestinal Diseases Tretinoin 12.2217994277
MESH:D007414 Intestinal Neoplasms Plant Extracts 3.9312351151 12584176 12628509
MESH:D019586 Intracranial Hypertension Indomethacin 4.5815241188
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.239022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 7.5916580747
MESH:D007569 Jaw Abnormalities Tretinoin 7.5917551590 15992940
MESH:D007579 Jejunal Diseases Indomethacin 4.2316133968 18306037 10574470
MESH:D007627 Keloid Quercetin 4.1917086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.6515604871
MESH:D007642 Keratosis Arsenic 4.2116930632 12749816
MESH:D007674 Kidney Diseases Acetaminophen 33.4015629191 12587719
MESH:D007674 Kidney Diseases Acrolein 33.4012488133
MESH:D007674 Kidney Diseases Cadmium 33.4016322080 16226777 16962696
MESH:D007674 Kidney Diseases Cadmium Chloride 33.4016962696
MESH:D007674 Kidney Diseases Cyclosporine 33.408314463 10903974 18776723
MESH:D007674 Kidney Diseases Doxorubicin 33.4015699352 15369732 16775033
MESH:D007674 Kidney Diseases Estradiol 33.4015618244
MESH:D007674 Kidney Diseases Furosemide 33.4011041285
MESH:D007674 Kidney Diseases Indomethacin 33.4017190690
MESH:D007674 Kidney Diseases Quercetin 33.4016962696
MESH:D007676 Kidney Failure, Chronic Doxorubicin 12.6816707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 12.6816518626
MESH:D007676 Kidney Failure, Chronic Selenium 12.6816518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 20.7616705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 20.7616705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 20.766582329
MESH:D007680 Kidney Neoplasms Cyclosporine 20.7612371664
MESH:D007680 Kidney Neoplasms Estradiol 20.7615610895
MESH:D007680 Kidney Neoplasms Fluorouracil 20.7616985049
MESH:D007896 Leishmaniasis Nitric Oxide 3.9917218153
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.2610320625 12228301 11703811
MESH:D007938 Leukemia arsenic trioxide 11.2015070760
MESH:D007938 Leukemia Genistein 11.2017468513 18980019
MESH:D007938 Leukemia Quercetin 11.2017468513
MESH:D007938 Leukemia Tretinoin 11.2017143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.3616085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 12.4417077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell bortezomib 12.4418089816
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell zoledronic acid 12.4418089816
MESH:D007948 Leukemia, Monocytic, Acute anthra(1,9-cd)pyrazol-6(2H)-one 15.2216972261
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 15.2216972261
MESH:D007948 Leukemia, Monocytic, Acute U 0126 15.2216972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 6.5414633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 6.5415631656 16572323 10785260
MESH:D007951 Leukemia, Myeloid arsenic trioxide 7.1419077051
MESH:D007951 Leukemia, Myeloid Tretinoin 7.1419285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 7.0120471514 19850784 16467208 17050201 16968895
MESH:D015470 Leukemia, Myeloid, Acute bortezomib 7.0120471514
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 7.0118360721
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 7.0116294345 17596541 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 13.6417339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 13.6419035177 16330433 19642359 15622746 16823087 15748426 12712474 17869043 17649720 17712046 17107899 15336539 11468182 12018890 16112521 17217047 15213294 12679006 16891316 16331271 19225113 9834237 16966277 11161223 19075265
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 13.6416087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 13.6419225113 17506722 16766008 12679006 16140955 16891316 17107899 19075265 19642359 17361223 19035177 16788101 17301526 9834237 17217047 17294898 17339181 16823087 16935935 17649720 19029980 17712046 16331271 15748426 17368321
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.6116882451
MESH:D007964 Leukocytosis Indomethacin 4.5816537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 4.9217980183
MESH:D007972 Leukoplakia, Oral Fenretinide 5.2516707609
MESH:D017880 Limb Deformities, Congenital Tretinoin 2.729224671
MESH:D008080 Liposarcoma Paclitaxel 4.1017353645
MESH:D008101 Liver Abscess, Amebic Indomethacin 4.9211479899
MESH:D008103 Liver Cirrhosis Plant Extracts 3.2617157831
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.6615034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 16.9716439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 16.9714716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 16.9717823541
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 16.9718194892
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 16.9715474484
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 16.9715479170
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 16.9712741479
MESH:D008106 Liver Cirrhosis, Experimental silybin 16.9716169303
MESH:D008106 Liver Cirrhosis, Experimental Taurine 16.9715931870 15893842
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 16.9712878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 16.9718397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 5.0219784758 16610002 19014921 16611625 12969438 12587719 19460945 11587558
MESH:D008107 Liver Diseases Arsenic 5.0211134558
MESH:D008107 Liver Diseases Plant Extracts 5.0217034775
MESH:D017093 Liver Failure Galactosamine 5.4211023982
MESH:D017114 Liver Failure, Acute Acetaminophen 2.5516871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 29.607678174
MESH:D008113 Liver Neoplasms Arsenic 29.6016368122
MESH:D008113 Liver Neoplasms arsenic trioxide 29.6014682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 29.6020195826 21137059
MESH:D008113 Liver Neoplasms Fluorouracil 29.6017045692 16603448 18383874 15113037
MESH:D008113 Liver Neoplasms pirinixic acid 29.6015890375 20007298 16377806
MESH:D008113 Liver Neoplasms Plant Extracts 29.6019168119
MESH:D008113 Liver Neoplasms Quercetin 29.6018980244
MESH:D008113 Liver Neoplasms resveratrol 29.6019321006 19073162 20405173 19812893
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 29.6016984957
MESH:D008113 Liver Neoplasms Urethane 29.6016391232 17559639 17093202
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 16.452876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 16.451399818 6587162 598648 3712494
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 16.4520377131
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 16.4516842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Quercetin 16.4519519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 16.4512151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.7415213294
MESH:D008171 Lung Diseases Acrolein 6.0511504702
MESH:D008171 Lung Diseases Mustard Gas 6.0518161513 18702808
MESH:D055370 Lung Injury Nitric Oxide 3.9811395602
MESH:D008175 Lung Neoplasms Arsenic 19.0019168569 17976673 17306315
MESH:D008175 Lung Neoplasms arsenic trioxide 19.0019825857 11798837
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 19.0018569708 20064080 18816296 20869020 20135361 17053015 6695378 20464547 18520028
MESH:D008175 Lung Neoplasms Doxorubicin 19.0017418594 6189445
MESH:D008175 Lung Neoplasms Fluorouracil 19.0015246190
MESH:D008175 Lung Neoplasms Indomethacin 19.0011497255 16537180 11053908
MESH:D008175 Lung Neoplasms Mustard Gas 19.003148597 8781369
MESH:D008175 Lung Neoplasms Plant Extracts 19.0020869020
MESH:D008175 Lung Neoplasms Quercetin 19.0016280456
MESH:D008175 Lung Neoplasms silybin 19.0016788158
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 19.0019555203 11884234
MESH:D008175 Lung Neoplasms Urethane 19.0015136453 10822126 16788158 12957351 12117781 11893704 10997738 16391232 16204055 16289808 11992545 6695378 17093202 12466968 16007126 11544531 10530776 15902970 16926031 11497255 17195641 11246140 12765245 7750092 15166089 16337739 11323394 10779650 17255336 14587096 11062179 11552296 11807781 11307925 11074608
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.0115086387
MESH:D008223 Lymphoma bortezomib 13.1916098063
MESH:D008223 Lymphoma Doxorubicin 13.1916098063
MESH:D008223 Lymphoma Etoposide 13.1912854902 12556972
MESH:D008223 Lymphoma Nitric Oxide 13.1916166326
MESH:D016393 Lymphoma, B-Cell bortezomib 8.3416675587
MESH:D016393 Lymphoma, B-Cell resveratrol 8.3417088997
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 10.8717654614
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 10.8714749477
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 10.8714749477
MESH:D016399 Lymphoma, T-Cell Doxorubicin 3.8115621674
MESH:D016410 Lymphoma, T-Cell, Cutaneous vorinostat 4.9220479100
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.4815688416
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 23.9815458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 23.9811807958 11408345 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 23.9810697514
MESH:D008325 Mammary Neoplasms, Experimental Genistein 23.9812929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 23.9817203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 23.9811606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental Selenium 23.9815318939
MESH:D008325 Mammary Neoplasms, Experimental zoledronic acid 23.9817312309
MESH:D020149 Manganese Poisoning Estradiol 3.6919453300
MESH:D008527 Medulloblastoma bortezomib 5.6119213072
MESH:D008527 Medulloblastoma Tretinoin 5.6117453147
MESH:D008545 Melanoma 2-methoxyestradiol-3,17-bis-O,O-sulfamate 9.7414970876
MESH:D008545 Melanoma Doxorubicin 9.7416827129
MESH:D008545 Melanoma Fenretinide 9.7416270382
MESH:D008545 Melanoma Paclitaxel 9.7412025231 12040289 16342250
MESH:D008545 Melanoma resveratrol 9.7417992120
MESH:D008545 Melanoma Tretinoin 9.7416752155
MESH:D008546 Melanoma, Experimental Acetaminophen 8.4719513568
MESH:D008546 Melanoma, Experimental Acrolein 8.4710803710
MESH:D008591 Meningomyelocele Tretinoin 3.6616940565
MESH:D008654 Mesothelioma Doxorubicin 8.0617638057
MESH:D008654 Mesothelioma Selenium 8.0615107826
MESH:D008654 Mesothelioma zoledronic acid 8.0616675582
MESH:D008659 Metabolic Diseases resveratrol 3.6717112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 3.9916801185
MESH:D008881 Migraine Disorders Indomethacin 6.1611903285
MESH:D008881 Migraine Disorders Nitric Oxide 6.1611701602
MESH:D020326 Migraine without Aura Nitric Oxide 4.3711304026 14659530
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.7915792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 15.4616381670
MESH:D009062 Mouth Neoplasms Fenretinide 15.4616274795
MESH:D009062 Mouth Neoplasms Fluorouracil 15.4616757204 18986760
MESH:D009062 Mouth Neoplasms Indomethacin 15.4612636206
MESH:D052016 Mucositis Doxorubicin 4.0117415656
MESH:D009101 Multiple Myeloma arsenic trioxide 16.4911468182 14977855 15949261 19417148 19549372
MESH:D009101 Multiple Myeloma bortezomib 16.4919112817 19372569 19112201
MESH:D009101 Multiple Myeloma Paclitaxel 16.4914749477
MESH:D009101 Multiple Myeloma resveratrol 16.4914749477 16490592 17935668 16267019 17049120 17164350
MESH:D009101 Multiple Myeloma zoledronic acid 16.4916996129 18089719 19621390
MESH:D020529 Multiple Sclerosis, Relapsing-Remitting Minocycline 5.9811835378
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.0917962980
MESH:D009135 Muscular Diseases pirinixic acid 2.7516239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.8818349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 5.7116105982 16882451
MESH:D009190 Myelodysplastic Syndromes Tretinoin 5.7117596541
MESH:D009203 Myocardial Infarction Cocaine 17.2118072171
MESH:D009203 Myocardial Infarction Doxorubicin 17.2119429709 15857846
MESH:D009203 Myocardial Infarction Genistein 17.2117141266
MESH:D009203 Myocardial Infarction pirinixic acid 17.2119151258
MESH:D009203 Myocardial Infarction Quercetin 17.2119595682
MESH:D009203 Myocardial Infarction resveratrol 17.2116317513 16525036 17015251 17125593 16456233 17188708
MESH:D017202 Myocardial Ischemia Arsenic 11.6115371236
MESH:D017202 Myocardial Ischemia resveratrol 11.6117125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 11.6112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 15.2016810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 15.2017141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 15.2016411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 15.2019207477
MESH:D009205 Myocarditis resveratrol 3.9817322642
MESH:D009325 Nausea vorinostat 4.7420479100
MESH:D009336 Necrosis 2,4-dinitrotoluene 7.7818551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 7.7818551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.2216624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 13.803581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 13.8018259882
MESH:D009362 Neoplasm Metastasis Indomethacin 13.8011239499 16537180 11053908
MESH:D009362 Neoplasm Metastasis Paclitaxel 13.8015867366
MESH:D009362 Neoplasm Metastasis zoledronic acid 13.8017312309 19139120 15867366
MESH:D009369 Neoplasms Acrolein 27.4617329238
MESH:D009369 Neoplasms Benzo(a)pyrene 27.4611141357
MESH:D009369 Neoplasms codonoposide 27.4615863893
MESH:D009369 Neoplasms echinocystic acid 27.4615863893
MESH:D009369 Neoplasms Fenretinide 27.4615958647 17353921
MESH:D009369 Neoplasms Fluorouracil 27.4616928823 18600527 18239605
MESH:D009369 Neoplasms pirinixic acid 27.4617405874
MESH:D009369 Neoplasms Quercetin 27.4615185748
MESH:D009369 Neoplasms Tretinoin 27.4616594593 16946489
MESH:D009369 Neoplasms Urethane 27.4615625555
MESH:D009374 Neoplasms, Experimental Indomethacin 11.1515625704 10663608
MESH:D009374 Neoplasms, Experimental resveratrol 11.158985016
MESH:D009374 Neoplasms, Experimental Urethane 11.1515582191
MESH:D009389 Neovascularization, Pathologic 2-methoxyestradiol-3,17-bis-O,O-sulfamate 12.9717426705
MESH:D009389 Neovascularization, Pathologic Estradiol 12.9717289903
MESH:D009389 Neovascularization, Pathologic parthenolide 12.9716921510
MESH:D009393 Nephritis Acrolein 5.4912653641
MESH:D009395 Nephritis, Interstitial Minocycline 5.14444868 435818
MESH:D009397 Nephrocalcinosis Furosemide 5.0815086907
MESH:D009401 Nephrosis Doxorubicin 4.0116899518 16636307
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.6517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 7.0718481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 7.0716889571 15640375
MESH:D009421 Nervous System Malformations Estradiol 17.4116427766 11399458
MESH:D009421 Nervous System Malformations Genistein 17.4116427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 17.4114600291
MESH:D009421 Nervous System Malformations Tretinoin 17.419125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 12.796679447
MESH:D009436 Neural Tube Defects Arsenic 12.7916620997
MESH:D009436 Neural Tube Defects arsenic trioxide 12.7910525206
MESH:D009436 Neural Tube Defects Tretinoin 12.799142499
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 4.4217168769
MESH:D009447 Neuroblastoma Doxorubicin 5.7315555623
MESH:D009447 Neuroblastoma Topotecan 5.7315176712
MESH:D019636 Neurodegenerative Diseases Acetaminophen 14.8418514411
MESH:D019636 Neurodegenerative Diseases Acrolein 14.8411342003
MESH:D019636 Neurodegenerative Diseases Indomethacin 14.8412349958
MESH:D019636 Neurodegenerative Diseases resveratrol 14.8417652729
MESH:D020078 Neurogenic Inflammation Arsenic 13.6517056641
MESH:D020078 Neurogenic Inflammation Quercetin 13.6517929310
MESH:D020078 Neurogenic Inflammation resveratrol 13.6517929310
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 4.9016303764
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 2.8716436463
MESH:D009503 Neutropenia Mustard Gas 3.267688884 16761898
MESH:D053206 Nocturnal Enuresis Furosemide 5.0817945291
MESH:D009765 Obesity pirinixic acid 3.8520558911
MESH:D009765 Obesity Plant Extracts 3.8520132043 19056576
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.386374098
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 11.1112819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 11.1116049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 11.116482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.233988306
MESH:D010003 Osteoarthritis Indomethacin 3.157009135
MESH:D010014 Osteolysis Paclitaxel 9.7115867366
MESH:D010014 Osteolysis zoledronic acid 9.7115867366
MESH:D010024 Osteoporosis Genistein 5.8019401787
MESH:D010024 Osteoporosis zoledronic acid 5.8017882678
MESH:D015663 Osteoporosis, Postmenopausal Genistein 12.7416169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 12.7419495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 12.7417513867
MESH:D012516 Osteosarcoma Doxorubicin 3.4715930896
MESH:D010051 Ovarian Neoplasms Arsenic 40.4517306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 40.4512452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Estradiol 40.4519401270
MESH:D010051 Ovarian Neoplasms Fenretinide 40.4516133793
MESH:D010051 Ovarian Neoplasms Genistein 40.4519005980
MESH:D010051 Ovarian Neoplasms Mifepristone 40.4516525653
MESH:D010051 Ovarian Neoplasms Paclitaxel 40.4511161223
MESH:D010051 Ovarian Neoplasms phenoxodiol 40.4516388521
MESH:D010051 Ovarian Neoplasms Progesterone 40.4517393432 16525653
MESH:D010051 Ovarian Neoplasms Quercetin 40.4519005980
MESH:D010051 Ovarian Neoplasms Tretinoin 40.4516936753
MESH:D010051 Ovarian Neoplasms U 0126 40.4516211241
MESH:D010051 Ovarian Neoplasms Urethane 40.4516391232
MESH:D010146 Pain Acetaminophen 10.9016870215
MESH:D010146 Pain Indomethacin 10.9013679232 17440234 3291741 17627676
MESH:D010146 Pain Tretinoin 10.9016870215
MESH:D010146 Pain zoledronic acid 10.9016475674
MESH:D010149 Pain, Postoperative Indomethacin 3.8918702446 12538197
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 15.8015580305
MESH:D010190 Pancreatic Neoplasms Etoposide 15.8019003803
MESH:D010190 Pancreatic Neoplasms Fenretinide 15.8015580305
MESH:D010190 Pancreatic Neoplasms Fluorouracil 15.8016929163 19003803 16500647 15113037
MESH:D010190 Pancreatic Neoplasms Quercetin 15.8016965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 15.8015976015
MESH:D010195 Pancreatitis Indomethacin 3.2217883296 15028970
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 11.307296757
MESH:D010212 Papilloma Hydrogen Peroxide 11.3012065085
MESH:D010212 Papilloma Plant Extracts 11.3016517061 15173996
MESH:D010235 Paraganglioma arsenic trioxide 3.4419927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 4.9216537180
MESH:D010300 Parkinson Disease Acrolein 3.2517690948
MESH:D020734 Parkinsonian Disorders Indomethacin 3.4412349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 4.9211903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.4612520081
MESH:D010437 Peptic Ulcer Indomethacin 4.3711148446
MESH:D010518 Periodontitis Indomethacin 4.1217225004
MESH:D010523 Peripheral Nervous System Diseases Arsenic 3.4416093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 10.516392382 15371236 16905509
MESH:D016491 Peripheral Vascular Diseases Cadmium 10.5115687053
MESH:D010538 Peritonitis Isoflurane 4.4717414419
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 10.466228378
MESH:D010787 Photosensitivity Disorders Acrolein 10.4611550810
MESH:D003557 Phyllodes Tumor Doxorubicin 4.3617983394
MESH:D010911 Pituitary Neoplasms Urethane 4.6516391232
MESH:D010954 Plasmacytoma Selenium 4.1015087411
MESH:D010997 Pleural Neoplasms Doxorubicin 4.3617638057
MESH:D011015 Pneumonia, Aspiration Nitric Oxide 4.5618573544
MESH:D011041 Poisoning Mustard Gas 3.0915727166
MESH:D011141 Polyuria Furosemide 4.8717945291
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.8218163543
MESH:D011230 Precancerous Conditions Cyclosporine 6.8812371664
MESH:D011230 Precancerous Conditions Quercetin 6.8819056647
MESH:D047928 Premature Birth Indomethacin 4.3717000239
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 7.0316679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 7.0311399792 11896295 11222880 11118676
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.1820887781
MESH:D011471 Prostatic Neoplasms Arsenic 11.9616140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 11.9619131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 11.9617292933
MESH:D011471 Prostatic Neoplasms Cadmium 11.9617075824
MESH:D011471 Prostatic Neoplasms Doxorubicin 11.9618437689 16729912 16868541 15749863 15897917 16888761
MESH:D011471 Prostatic Neoplasms Estradiol 11.9616740699
MESH:D011471 Prostatic Neoplasms Etoposide 11.9617172428
MESH:D011471 Prostatic Neoplasms Fenretinide 11.9617024972
MESH:D011471 Prostatic Neoplasms Fluorouracil 11.9619082440 18626508
MESH:D011471 Prostatic Neoplasms Genistein 11.9615256057 15378649 16925846
MESH:D011471 Prostatic Neoplasms Nordihydroguaiaretic Acid 11.9618491370
MESH:D011471 Prostatic Neoplasms Paclitaxel 11.9616729912 17136230 17172428 16356831
MESH:D011471 Prostatic Neoplasms panduratin A 11.9616497706
MESH:D011471 Prostatic Neoplasms parthenolide 11.9616921510
MESH:D011471 Prostatic Neoplasms Phellinus linteus extract 11.9616868541
MESH:D011471 Prostatic Neoplasms Plant Extracts 11.9617804756 14666653
MESH:D011471 Prostatic Neoplasms Quercetin 11.9614715546 17292933
MESH:D011471 Prostatic Neoplasms resveratrol 11.9617636462 16731767 17804756 17718901 17675339 15767336
MESH:D011471 Prostatic Neoplasms vorinostat 11.9617218635
MESH:D011471 Prostatic Neoplasms zoledronic acid 11.9619103299 12438248
MESH:D011507 Proteinuria Arsenic 11.3621343184
MESH:D011507 Proteinuria Indomethacin 11.3611849393
MESH:D011507 Proteinuria Tretinoin 11.3616636307
MESH:D011537 Pruritus Mustard Gas 3.3318058305
MESH:D011565 Psoriasis Cyclosporine 1.8916882103
MESH:D011618 Psychotic Disorders Cocaine 4.2316134406
MESH:D011625 Pterygium Tretinoin 4.0116723453
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.5717720292 10334151 17620002 17266442 17894541
MESH:D012004 Rectal Neoplasms Fluorouracil 3.3418722050 18286688 16160472 15538739
MESH:D051437 Renal Insufficiency Acrolein 8.0912732208
MESH:D051437 Renal Insufficiency Doxorubicin 8.0917922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.7916325855
MESH:D015427 Reperfusion Injury Furosemide 8.4316526316
MESH:D015427 Reperfusion Injury pirinixic acid 8.4319058328
MESH:D015427 Reperfusion Injury resveratrol 8.4317058453 17520802 16317513 15827377 16314181
MESH:D012128 Respiratory Distress Syndrome, Adult Furosemide 3.9015912074 12394941 16096441
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.0918990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 7.083692021
MESH:D012162 Retinal Degeneration Fenretinide 7.0816303925
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.3816116481 16283617
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.5118045962
MESH:D012509 Sarcoma Doxorubicin 3.3116767912 18313854 17203757 15675481 15625365 17710206
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 18.6216646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 18.6214601052 16326096
MESH:D012512 Sarcoma, Ewing's Etoposide 18.6214601052
MESH:D012512 Sarcoma, Ewing's zoledronic acid 18.6216121404
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.0117846226
MESH:D012554 Schistosomiasis japonica Quercetin 4.7516862918
MESH:D012555 Schistosomiasis mansoni Nitric Oxide 4.719673227
MESH:D012640 Seizures 2,4-dinitrotoluene 6.7318551238
MESH:D012640 Seizures 2,6-dinitrotoluene 6.7318551238
MESH:D012640 Seizures Cocaine 6.7310454489
MESH:D018805 Sepsis Isoflurane 4.3417414419
MESH:D012871 Skin Diseases Arsenic 6.4617548696 17453740 17050553 17938729 15952646 16759981 16353154 19834688 18709164 6392382 16702368
MESH:D012871 Skin Diseases monomethylarsonous acid 6.4617431481
MESH:D012871 Skin Diseases Mustard Gas 6.4616961503 15451306 12880345
MESH:D012878 Skin Neoplasms Arsenic 32.4715504454 17050553 19538983 16251483 17976673 17029826
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 32.4719755658 10029692
MESH:D012878 Skin Neoplasms Doxorubicin 32.4715692506
MESH:D012878 Skin Neoplasms Fenretinide 32.4716467112
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 32.4712065085
MESH:D012878 Skin Neoplasms Plant Extracts 32.4715173996 16517061
MESH:D012878 Skin Neoplasms resveratrol 32.4715837718 8985016
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 32.4716192470
MESH:D012878 Skin Neoplasms Tretinoin 32.4716467112
MESH:D012878 Skin Neoplasms Urethane 32.4711807781
MESH:D012893 Sleep Disorders Caffeine 4.5419395429
MESH:D007319 Sleep Initiation and Maintenance Disorders Caffeine 4.3217225163
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.8116767912 17203757 15625365
MESH:D013119 Spinal Cord Injuries Progesterone 3.5115862959 16503802
MESH:D013272 Stomach Diseases Indomethacin 3.6517207306 15038085 17160473 16113693 15472012 18545984 10486359 16184426 10215738 17638125 10192188 16280098 18209964
MESH:D013274 Stomach Neoplasms marker/mechanism 15095271
MESH:D013274 Stomach Neoplasms arsenic trioxide 8.3417007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 8.3420155912 2093021
MESH:D013274 Stomach Neoplasms Fluorouracil 8.3417498489 15786421 19015929 17172411 16951190 16424979 18567086 18396642 19084572 17522103
MESH:D013274 Stomach Neoplasms Furosemide 8.3417052386
MESH:D013274 Stomach Neoplasms Indomethacin 8.3415609394
MESH:D013274 Stomach Neoplasms Paclitaxel 8.3418396642 18506536
MESH:D013274 Stomach Neoplasms Tretinoin 8.3417261132
MESH:D013276 Stomach Ulcer Indomethacin 8.3511523592 17654042 12077510 17895592 16252198 11906479 10750652 12787963 15138204 16631530 11145282 17977527 12500499 18726076 17135157 18209962 18543354 10878458 18431645 17918041 18237397 12498302 10423059 16934674 16150113 12467913 16397915 14567935 15104355 15255614 1323529 18181030 17627676 11595431 16755016 16169175 17657623 18299717 11729361 18193104 11595415 18087811
MESH:D013276 Stomach Ulcer Nitric Oxide 8.3515138204
MESH:D013276 Stomach Ulcer Plant Extracts 8.3515255614 17135157 12787963 18237397 18193104
MESH:D020521 Stroke Acrolein 3.9216269634
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.7916321402
MESH:D013345 Subarachnoid Hemorrhage pifithrin 5.2718364113
MESH:D024801 Tauopathies Camptothecin 9.2616930453
MESH:D024801 Tauopathies Paclitaxel 9.2616930453
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 4.6917997062
MESH:D013733 Testicular Diseases phenethyl isothiocyanate 8.2915864552
MESH:D013733 Testicular Diseases pyrazole 8.296499806
MESH:D013921 Thrombocytopenia vorinostat 4.2920479100
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.1112697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 20.101399818 3712494 6587162 6582329 7505956
MESH:D013964 Thyroid Neoplasms arsenic trioxide 20.1019014326
MESH:D013964 Thyroid Neoplasms Butyrates 20.1017967635
MESH:D013964 Thyroid Neoplasms Doxorubicin 20.1016010429 17909728
MESH:D013964 Thyroid Neoplasms Indomethacin 20.1018791128 14736730 11352223
MESH:D013964 Thyroid Neoplasms Tretinoin 20.1016026305 17045167
MESH:D013978 Tibial Fractures Estradiol 3.8919048282
MESH:D014062 Tongue Neoplasms Fluorouracil 12.6216280240
MESH:D014062 Tongue Neoplasms resveratrol 12.6216227395
MESH:D014062 Tongue Neoplasms Tretinoin 12.6216051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.1915213294
MESH:D014376 Tuberculosis Tretinoin 2.6916040207
MESH:D014456 Ulcer Indomethacin 4.1217380554 10574470
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 29.1416049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 29.1416049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 29.148074119
MESH:D001749 Urinary Bladder Neoplasms Arsenic 29.1417976673 11144890 19429237 17306315 18640142 19322015 15987713
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 29.1412845720 11780464 12973940 20435036
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 29.1417053015
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 29.1417653716
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 29.1416720286
MESH:D001749 Urinary Bladder Neoplasms monomethylarsonous acid 29.1420375083
MESH:D001749 Urinary Bladder Neoplasms Quercetin 29.1416720314
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 9.4110091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 9.4110091137
MESH:D014581 Urticaria Acetaminophen 2.2710982225
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 17.0716154183
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 17.0716803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 17.0717473185
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 17.0716129372
MESH:D014594 Uterine Neoplasms resveratrol 7.5517044934
MESH:D014594 Uterine Neoplasms sulindac sulfide 7.5518645019
MESH:D014604 Uveal Neoplasms Tretinoin 3.8216752155
MESH:D014605 Uveitis Cyclosporine 3.191336536
MESH:D014652 Vascular Diseases Arsenic 3.9617056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.8012125929
MESH:D019043 Vascular Neoplasms Urethane 5.1210620525
MESH:D020301 Vasospasm, Intracranial pifithrin 4.8418364113
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 12.8817638931 17678736 16364871 17334414
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 12.8818097624
MESH:D018487 Ventricular Dysfunction, Left resveratrol 12.8817488730
MESH:D020257 Ventricular Remodeling Plant Extracts 4.5418097624
MESH:D014820 Vitiligo Tretinoin 3.3216761959
MESH:D014839 Vomiting Indomethacin 3.9611897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.4615886252
MESH:D009396 Wilms Tumor Tretinoin 3.2916287080
MESH:D014947 Wounds and Injuries Plant Extracts 3.6120213670 19894650
MESH:D014985 Xerophthalmia Cyclosporine 3.6517120751
Pathway ID Pathway Name
KEGG:05010 Alzheimer's disease
KEGG:05014 Amyotrophic lateral sclerosis (ALS)
KEGG:04210 Apoptosis
REACT:578 Apoptosis
KEGG:04650 Natural killer cell mediated cytotoxicity
KEGG:04115 p53 signaling pathway
KEGG:05200 Pathways in cancer
KEGG:05152 Tuberculosis
KEGG:05416 Viral myocarditis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA25353
    • No data
    Releated disease ID Related disease Name
    PA443622Carcinoma, Non-Small-Cell Lung
    Releated drug ID Related drug Name
    PA449780glutathione
    PA449014cisplatin
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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